Medicine and Health Sciences Commons^™

Introduction, Peter J. Strauss

NYLS Law Review

No abstract provided.

The Development Of Intimate Partner Relationships Among Men Sexually Abused As Children, Laura Beltran-Medina

Antioch University Dissertations & Theses

This phenomenological study sought to understand the experience of seven men who came forward to contribute and discuss their intimate partner relationships for what relational intimacy could reveal about themselves, the meaning of intimate partnership, and their understanding of being in intimate relationships. The theoretical assumptions applied to this study are: (a) Childhood sexual abuse interferes with the ability to achieve deeper experiences of idealized love; (b) Negative effects of adult relational attachment are manifested in anxiety related to sexual intimacy, fear of emotional intimacy, and inability to fulfill dependency needs such as trust, love, and security; and (c) There …

Allied Health Evaluation Review: Practice And Education Infrastructure, Mardi Lowe-Heistad, Sandra Lowe

Internet Journal of Allied Health Sciences and Practice

The Allied Health Evaluation Review: Practice and Education Infrastructure was a detailed review of the practice progress of twenty-seven allied health professions. The key objectives of the evaluation review were to determine each profession’s practice status, measured on a common set of parameters that could be compared to one another at a given point in time, and to identify what variables, if any, were correlated with the practice progress of a given profession. Practice benchmarks were established and tools were developed to measure the practice progress of each profession relative to the others at a given point in time. The …

Isometric Force Production Symmetry And Jumping Performance In Collegiate Athletes, Chris A. Bailey, Kimitake Sato, Ryan Alexander, Chieh-Ying Chiang, Michael H. Stone

ETSU Faculty Works

Objectives: The purpose of this study was to identify the relationship between isometric force production symmetry and jumping performance in weighted and un-weighted static and countermovement jumps (SJ and CMJ). Design: Bivariate correlation between isometric force production symmetry and vertical jump performance variables. Methods: Collegiate athletes were evaluated for this study (n=36). Subjects performed SJ, CMJ, and isometric mid-thigh pulls (IMTP). Jumps were analyzed for jump height (JH) and peak power (PP). IMTP was analyzed for peak force (PF) for left and right sides, and values were calculated to produce a peak force symmetry index (PF-SI) score. Correlational statistics were …

Using Benefits Based Models To Manage Sport Performance Enhancement Groups, Anna Swisher, Andy R. Dotterweich, Sterlynn Clendenin, Mauro Palmero, Amy E. Greene, Joseph T. Abbott, Heather Habbott, Jana Hollins

ETSU Faculty Works

No abstract provided.

Predictors Of Treatments Acceptable To Patients For Late-Life Depression, Gerald J. Jogerst, Shimin Zheng, Erik Vanderlip

ETSU Faculty Works

Objectives. Describe older patients’ perceptions about depression and characteristics associated with acceptance of treatments. Design. Cross-sectional study. Setting. Three primary care clinics in Iowa. Participants. Consecutive sample of 529 primary care patients. Measurements. Depression screening tool (a 9-item patient health questionnaire [PHQ-9]) and questionnaire including sociodemographic data, patient attitudes about depression, and acceptability of different treatments. Results. Mean age was 71.9 years (range 60–93 years), 314 (59%) female. Among the 529 participants, 93 (17.5%) had history of depression and 60 (11.3%) had PHQ-9 scores of 10 or greater. Participants believed depression is a disease for which they would use medication …

Examination Of Changes In Youth Diet And Physical Activity Over The Summer Vacation Period, Meghan C. Mccue, Kara L. Marlatt, John Sirard

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was to examine weight, diet, and physical activity (PA) changes in youth over summer vacation. Methods: Thirty healthy subjects (19 male, 11 female; mean age + SEM 10.0+0.1 yrs) were assessed before the end of the 2009/2010 school year (baseline), and prior to the start of the 2010/2011 school year (post-test).Results: Significant (p< 0.05) increases in height, weight, body mass index (BMI), and BMI percentile-for-age were observed. Percent time spent in light (p=0.002) and moderate (p=0.014) PA intensities both decreased, while time spent being sedentary significantly (p=0.006) increased. No significant diet changes were reported. Conclusion: This healthy youth population increased time spent being sedentary at the expense of light and moderate PA over summer vacation. The result was an increase in BMI and BMI percentile-for-age. Future studies are needed to examine ways to prevent this decline in PA in youth over summer vacation.

“24” – Hours To Discharge After Robotic Surgery For Complex Gynecologic Malignancies (Standards Of Care Even Jack Bauer Couldn’T Achieve, Sarah R. Mason Rn, Nicole Reimer Bsn, Rn, Ocn

Patient Care Services / Nursing

No abstract provided.

A Trauma Unit’S Interprofessional Approach To Reducing Catheter Associated Urinary Tract Infections, Kai L. Bortz Rn

Patient Care Services / Nursing

No abstract provided.

Care Transition Coach, Marlene Seidel Butz

Patient Care Services / Nursing

No abstract provided.

Translating Evidence To The Bedside: Recognizing Delirium, Michaelen Panzarella Msn, Rn, Ccrn

Patient Care Services / Nursing

No abstract provided.

Enhancing Bonding Of Mother And Infant, Krista D. Thomas Rn, Bsn, Jennifer King Rnc, Bsn

Patient Care Services / Nursing

No abstract provided.

Interruptions During Medication Administration In The Emergency Department, Judith Baker Rn, Julie Albertson, Sandra Sabbatini Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Effectively Translating Venous Thromboembolism (Vte) Evidence: Effort To "Stop That Clot!", Kristina Holleran Bsn, Rn, Debra Peter Msn, Rn-Bc

Patient Care Services / Nursing

No abstract provided.

Psychiatric Nursing Care For Patients With Cardiac Disease, Gail Stern Msn, Donna Petruccelli Msn, Crnp, Np-C, Jeanne Manavizadeh Bsn, Rn, Pccn

Patient Care Services / Nursing

No abstract provided.

The Inconsistency Of Providing Ventilation With A T-Piece Style Resuscitator: A Bench Model Study, Robin L. Angus Bs, Rrt-Nps, Kenneth Miller Med, Rrt-Nps, Chris Fenstermaker Ms, Rrt-Nps

Patient Care Services / Nursing

No abstract provided.

Avoidance Disruptive Effect Of Clozapine And Olanzapine Is Potentiated By Increasing The Test Trials: Further Test Of The Motivational Salience Hypothesis, Min Feng, Nan Sui, Ming Li

Department of Psychology: Faculty Publications

Antipsychotic drugs suppress animals’ ability to avoid an aversive stimulus in the conditioned avoidance response model (CAR). This behavioral effect is thought to reflect antipsychotic activity and is suggested to be mediated by a drug’s action in attenuating the motivational salience of a conditioned stimulus (CS). In the present study, we tested whether atypical antipsychotic drugs clozapine and olanzapine act through this behavioral mechanism by manipulating the number of avoidance test trials. We reasoned that more CS trials in the present of clozapine or olanzapine would afford the drug more opportunities to decrease the motivational salience of the CS, thus …

Glutaredoxin-2 Is Required To Control Proton Leak Through Uncoupling Protein-3, Ryan J. Mailloux, Jian Ying Xuan, Brittany Beauchamp, Marjorie F. Lou, Mary-Ellen Harper

School of Veterinary and Biomedical Sciences: Faculty Publications

Glutathionylation has emerged as a key modification required for controlling protein function in response to changes in cell redox status. Recently, we showed that the glutathionylation state of uncoupling protein-3 (UCP3) modulates the leak of protons back into the mitochondrial matrix, thus controlling reactive oxygen species production. However, whether or not UCP3 glutathionylation is mediated enzymatically has remained unknown because previous work relied on the use of pharmacological agents, such as diamide, to alter the UCP3 glutathionylation state. Here, we demonstrate that glutaredoxin-2 (Grx2), a matrix oxidoreductase, is required to glutathionylate and inhibit UCP3. Analysis of bioenergetics in skeletal muscle …

Extracorporeal Membranous Oxygenation Mimics Aortic Dissection On Cat Scan., Philip Batista, Nicholas C. Cavarocchi, Hitoshi Hirose

Department of Surgery Faculty Papers

A 66 year-old female presented with refractory acute congestive heart failure, cardiogenic shock, and ventricular tachyarrhythmia. Veno-arterial extracorporeal membrane oxygenation (ECMO) was placed via femoral cannulation for salvage and stabilized. CAT scan of the chest performed as a part of heart transplant work-up, demonstrated an unequal distribution of intravenous contrast in the aortic arch (Figure 1). Radiologist’s preliminary reading was of “aortic dissection” while in fact this is truly “normal ECMO flow”.

Better Health, But Less Justice: Widening Health Disparities After National Federation Of Independent Business V. Sebelius, Emily W. Parento, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

At the time it was enacted in 2010, the Patient Protection and Affordable Care Act (ACA) was widely applauded by health activists, as it meant that the United States would at last join the overwhelming majority of industrialized countries in providing its population with guaranteed access to affordable health care. Roughly half of the increase in access to health insurance was to come from the expansion of Medicaid eligibility to all U.S. citizens and legal residents with income below 138% of the Federal Poverty Level. However, the Supreme Court’s 2012 ruling in National Federation of Independent Business v. Sebelius ( …

Towards A Framework Convention On Global Health: A Transformative Agenda For Global Health Justice, Lawrence O. Gostin, Eric A. Friedman

Georgetown Law Faculty Publications and Other Works

International law has responded weakly to the inequities in health care, public health, and the broader determinates of health that collectively cause the greatest loss of lives and human potential every year. Approximately one-third of global deaths can be attributed to enduring and unconscionable inequities. Despite significant progress in improving global health over the past several decades, these inequities persist. Current global governance for health is inadequate to the task of resolving these inequities, from lack of accountability and enforcement to inadequate funding and the absence of leadership required to respond to the threats to health that arise from other …

An Economic Model To Value Companion Diagnostics In Non-Small-Cell Lung Cancer, Robert D. Lieberthal, Kellie Dudash, Rita S. Axelrod, Neil I. Goldfarb

College of Population Health Faculty Papers

Aim: An economic model was used to evaluate the potential economic impact and cost–effectiveness of companion diagnostic testing for patients with non-small-cell lung cancer (NSCLC). Materials & methods: A decision analysis model examined alternative patient management strategies for patients with advanced NSCLC who were not amenable to surgical treatment. A review of the literature provided the variables used to develop a timely base case and sensitivity analysis. A potential future scenario was also modeled. The model includes three options: conventional treatment (CT), new treatment (NT) and companion diagnostic (CD) strategy. Results: In the base case analysis based upon current data, …

What Are The Characteristics That Explain Hospital Quality? A Longitudinal Pridit Approach, Robert D. Lieberthal, Dominique M. Comer

College of Population Health Faculty Papers

Health outcomes vary substantially between high and low quality institutions, meaning the difference between life and death in some cases. Prior literature has identified a number of variables that can be used to determine hospital quality, but methodologies for combining variables into an overall measure of hospital quality are not well developed. This analysis builds on the prior investigation of hospital quality by evaluating a method originally developed for the detection of healthcare fraud, Pridit, in the context of determining hospital quality. We developed a theoretical model to justify the application of Pridit to the hospital quality setting and then …

Genetic Diversity Of Plasmodium Vivax Clinical Isolates From Southern Pakistan Using Pvcsp And Pvmsp1 Genetic Markers, Afsheen Raza, Najia K. Ghanchi, Ali M. Thaver, Sana Jafri, Mohammad A. Beg

Department of Pathology and Laboratory Medicine

Background:
Plasmodium vivax is the prevalent malarial species accounting for 70% of malaria burden in Pakistan; however, there is no baseline data on the circulating genotypes. Studies have shown that polymorphic loci of gene encoding antigens pvcsp and pvmsp1 can be used reliably for conducting molecular epidemiological studies. Therefore, this study aimed to bridge the existing knowledge gap on population structure on P. vivax from Pakistan using these two polymorphic genes.
Methods:
During the period January 2008 to May 2009, a total of 250 blood samples were collected from patients tested slide positive for P. vivax, at the Aga Khan …

Systematic Review Of Research Into The Psychological Aspects Of Prostate Cancer In Asia: What Do We Know?, Suzanne Kathleen Chambers, Melissa Karen Hyde, David Fu-Keung Ip, Jeffrey Charles Dunn, Robert Alexander Gardiner

Research outputs 2013

Background: To review the peer reviewed literature on the psychological aspects of the prostate cancer experience of men in Asia.

Materials and Methods: Medline and PsycINFO, CINAHL, ProQuest, and Web of Science (1999 – November Week 4, 2012) were searched. Inclusion criteria were: included men with prostate cancer and/or their partners or caregivers who identify as Asian recruited in an Asian country; and assessed health-related quality of life, psychological and social adjustment relating to prostate cancer and published in English after 1st January 1999 and prior to 30th November, 2012.

Study aims: design; quality; level of evidence, and key results …

Viral Escape From Hiv-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth Through Sequential Recognition Of Multiple Epitopes And Immunotypes, Constantinos K. Wibmer, Jinal N. Bhiman, Elin S. Gray, Nancy Tumba, Salim S. Abdool Karim, Carolyn Williamson, Lynn Morris, Penny L. Moore

Research outputs 2013

Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a participant in the CAPRISA Acute Infection Cohort (CAP257) whose plasma neutralized 84% of heterologous viruses. In this study we showed that breadth in CAP257 was largely due to the sequential, transient appearance of three distinct broadly neutralizing antibody specificities spanning the first 4.5 years of infection. The first specificity targeted an epitope in the V2 region of gp120 that was also recognized by strain-specific antibodies 7 weeks earlier. Specificity …

Enhancing The Uptake Of Learning Through Simulation In Health, Cobie Rudd

Research outputs 2013

The initial reason that a simulated learning environment (SLE) was pursued was to offer university-based health students a safe and authentic environment in which to learn and practise their skills. Since that time, some eight years later, experience has shown that an SLE needed multiple dimensions to its work, based on evidence. In addition, a new approach to applying and integrating learning through simulation within health curricula, that was replicable and affordable, was required...

The Validity Of The Distress Thermometer In Prostate Cancer Populations, Suzanne Chambers, Leah Zajdlewicz, Danny R. Youlden, Jimmie C. Holland, Jeff Dunn

Research outputs 2013

Background: The Distress Thermometer (DT) is widely recommended for screening for distress after cancer. However, the validity of the DT in men with prostate cancer and over differing time points from diagnosis has not been well examined. Method: Receiver operating characteristics analyses were used to evaluate the diagnostic accuracy of the DT compared with three commonly used standardised scales in two prospective and one cross-sectional survey of men with prostate cancer (n = 740, 189 and 463, respectively). Comparison scales included the Impact of Event Scale – Revised (IES-R, Study 1), the Hospital Anxiety and Depression Scale (HADS, Study 2) …

Internet-Based Photoaging Within Australian Pharmacies To Promote Smoking Cessation: Randomized Controlled Trial, Oksana Burford, Moyez Jiwa, Owen B. Carter, Richard Parsons, Delia Hendrie

Research outputs 2013

Background: Tobacco smoking leads to death or disability and a drain on national resources. The literature suggests that cigarette smoking continues to be a major modifiable risk factor for a variety of diseases and that smokers aged 18-30 years are relatively resistant to antismoking messages due to their widely held belief that they will not be lifelong smokers. Objective: To conduct a randomized controlled trial (RCT) of a computer-generated photoaging intervention to promote smoking cessation among young adult smokers within a community pharmacy setting. Methods: A trial was designed with 80% power based on the effect size observed in a …

Predicting Optimal Cancer Rehabilitation And Supportive Care (Polaris): Rationale And Design For Meta-Analyses Of Individual Patient Data Of Randomized Controlled Trials That Evaluate The Effect Of Physical Activity And Psychosocial Interventions On Health-Related Quality Of Life In Cancer Survivors, Laurien M. Buffart, Joeri Kalter, Mai Jm Chinapaw, Martijn W. Heymans, Neil K. Aaronson, Kerry S. Courneya, Paul B. Jacobsen, Robert Newton, Irma M. Verdonck-De Leeuw, Johannes Brug

Research outputs 2013

Effective interventions to improve quality of life of cancer survivors are essential. Numerous randomized controlled trials have evaluated the effects of physical activity or psychosocial interventions on health-related quality of life of cancer survivors, with generally small sample sizes and modest effects. Better targeted interventions may result in larger effects. To realize such targeted interventions, we must determine which interventions that are presently available work for which patients, and what the underlying mechanisms are (that is, the moderators and mediators of physical activity and psychosocial interventions). Individual patient data meta-analysis has been described as the ‘gold standard’ of systematic review …