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2012

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Articles 6031 - 6060 of 7308

Full-Text Articles in Medicine and Health Sciences

Optimum Temperature And Growth Performance Of Hatchery Reared Black Sea Flounder (Platichthys Flesus Luscus Pallas, 1814), İlhan Aydin, Orhan Ak, Ercan Küçük, Hamza Polat, Bi̇nnur Ceylan Jan 2012

Optimum Temperature And Growth Performance Of Hatchery Reared Black Sea Flounder (Platichthys Flesus Luscus Pallas, 1814), İlhan Aydin, Orhan Ak, Ercan Küçük, Hamza Polat, Bi̇nnur Ceylan

Turkish Journal of Veterinary & Animal Sciences

The present study focused on the effect of water temperature on growth and feed conversion ratio of juvenile Black Sea flounder (Platichthys flesus luscus; initial weight: 2.0 g ± 0.01 g). The experiment was carried out for 84 days with the following range of water temperatures: 13, 17, 21, and 25 °C. Growth, food consumption, and feed conversion ratio were the highest at 21 °C and the lowest at 13 °C. The growth rate of the fish increased with water temperatures up to 21 °C and it decreased significantly with a further increase in temperature. The conclusion of this study …


Full Length Cdna Synthesis Of Differentially Displayed Ests During Lactation In The Indian Buffalo (Bubalus Bubalis), Ajai Tripathi, Krishna M. Singh, Makrand N. Vaze, Umed V. Ramani, Dharamsi N. Rank, Chaitanya G. Joshi Jan 2012

Full Length Cdna Synthesis Of Differentially Displayed Ests During Lactation In The Indian Buffalo (Bubalus Bubalis), Ajai Tripathi, Krishna M. Singh, Makrand N. Vaze, Umed V. Ramani, Dharamsi N. Rank, Chaitanya G. Joshi

Turkish Journal of Veterinary & Animal Sciences

In the present study, antisense primers were designed from 7 differentially displayed expressed sequence tags (ESTs) previously identified at our laboratory. Total RNA was isolated from the mammary gland tissue of lactating buffalo to carry out 5' rapid amplification cDNA ends (RACE) PCR. 5' RACE PCR amplicons, ranging from 161 bp to 336 bp, were cloned and sequenced. These 5' RACE sequences were analyzed using the blastn (Megablast) bioinformatics tool available from NCBI. Of these 7, only one 5' mRNA sequence did not show a match in the available database and another 1 failed to show a match with any …


Seasonal And Group Effects On Dairy Cow Behavior In Large Yards, Akbar Nikkhah, Rasool Kowsar Jan 2012

Seasonal And Group Effects On Dairy Cow Behavior In Large Yards, Akbar Nikkhah, Rasool Kowsar

Turkish Journal of Veterinary & Animal Sciences

In mechanized modern dairy facilities with competitive environments, monitoring behavior provides opportunities to manipulate and optimize the nutritional, health, and social status of high-merit cows. The objective of the current study was to determine seasonal and cow group effects on the eating, ruminating, standing, and lying behaviors of dairy cows in large yards. Seasonal data on various behaviors of lactating cows in different production and lactation stages were collected continuously for 26 months, from December 2006 through February 2008. The herd had approximately 3000 dairy cattle housed in groups within specific yards. A total of 415 multiparous high-producing cows (MH), …


A Retrospective Study Of Anaplasma In Minnesota Cattle, Aneela Durrani, Sagar Goyal Jan 2012

A Retrospective Study Of Anaplasma In Minnesota Cattle, Aneela Durrani, Sagar Goyal

Turkish Journal of Veterinary & Animal Sciences

To determine the seroprevalence of Anaplasma in Minnesota cattle, the database of the Veterinary Diagnostic Laboratory (VDL), University of Minnesota was searched over a 10 year period (2001 to July 2010). A total of 438,407 bovine serum samples were tested by complement fixation test (CFT) and competitive enzyme linked immunosorbent test (cELISA). The positive rate of seroprevalence by CFT was 2.4% out of 211,484 samples, with a 0.13% anticomplementary result. The VDL at the University of Minnesota started using cELISA after 2002, and CFT application was suspended as diagnostic test for anaplasmosis after 2005 due to its complexity. With cELISA, …


Effect Of Fermented Protein Feedstuffs On Pig Production Performance, Nutrient Digestibility, And Fecal Microbes, Juan Chang, Qingqiang Yin, Pengpeng Wang, Weimin Wang, Ruiyu Zuo, Qiuhong Zheng, Junxi Liu Jan 2012

Effect Of Fermented Protein Feedstuffs On Pig Production Performance, Nutrient Digestibility, And Fecal Microbes, Juan Chang, Qingqiang Yin, Pengpeng Wang, Weimin Wang, Ruiyu Zuo, Qiuhong Zheng, Junxi Liu

Turkish Journal of Veterinary & Animal Sciences

In order to determine the availability of fermented protein feedstuffs (FPFS)-such as cottonseed, blood, and feather meals—with Aspergillus oryzae, 2 phases of feeding experiments were adopted for 7 weeks. Sixty 58-day-old crossbred pigs were assigned to 6 groups, 10 pigs per group. Group 1 was the control; groups 2, 3, and 4 were supplemented with 6%-7%, 12%-14%, and 18%-21% FPFS, respectively, by replacing the same percentage of soybean meal (SBM); group 5 was supplemented with 12%-14% unfermented protein feedstuffs (UFPFS) by replacing the same percentage of SBM; group 6 was on the same base as group 3 with digestive energy …


Detection, Cloning, And Sequencing Of The Enterotoxin Gene Of Clostridium Perfringens Type C Isolated From Goat, Yuan Tang, Ming Wen, Bin Lian, Jianzhong Cheng, Kaigong Wang, Bijun Zhou Jan 2012

Detection, Cloning, And Sequencing Of The Enterotoxin Gene Of Clostridium Perfringens Type C Isolated From Goat, Yuan Tang, Ming Wen, Bin Lian, Jianzhong Cheng, Kaigong Wang, Bijun Zhou

Turkish Journal of Veterinary & Animal Sciences

Clostridium perfringens enterotoxin (CPE) is an important virulence factor involved in C. perfringens food poisoning and other gastrointestinal illnesses. In our experiment a Clostridium perfringens enterotoxin gene (cpe) positive type C strain was obtained by multiplex PCR from 34 C. perfringens isolates from goat in Guizhou Province, China. Then a pair of specific primers was designed and synthesized according to the published cpe gene, and the complete cpe gene was amplified from the genomic DNA of the cpe-positive C. perfringens isolate. The PCR product was cloned into pMD18-T vectors and transformed into competent cell DH5a. The recombinant plasmid was identified …


The Effect Of Bleeding On Peripheral Blood And Head Kidney Hematopoietic Tissue In Common Carp (Cyprinus Carpio), Elzbieta Kondera, Aneta Dmowska, Monika Rosa, Malgorzata Witeska Jan 2012

The Effect Of Bleeding On Peripheral Blood And Head Kidney Hematopoietic Tissue In Common Carp (Cyprinus Carpio), Elzbieta Kondera, Aneta Dmowska, Monika Rosa, Malgorzata Witeska

Turkish Journal of Veterinary & Animal Sciences

Adverse environmental conditions (contamination of water with nitrite, pesticides, or other pollutants), nutritional deficiencies, bacterial and viral infections, and parasitic invasions may induce anemia in fish, in both natural and aquaculture conditions. Changes in hematological values and cellular composition of peripheral blood and head kidney hematopoietic tissue of bled common carp (Cyprinus carpio L.) were evaluated over a 4 week period post-bleeding (30% blood loss). The results showed that fish very quickly compensated for anemia. Erythrocyte count (RBC), hemoglobin concentration (Hb), and hematocrit (Ht) gradually increased to values significantly higher than they were before bleeding; this was accompanied by an …


The Effect Of Different Extenders On The Motility And Morphology Of Ram Sperm Frozen Or Stored At 4 °C, Recai̇ Kulaksiz, Çi̇ğdem Çebi̇, Ergün Akçay Jan 2012

The Effect Of Different Extenders On The Motility And Morphology Of Ram Sperm Frozen Or Stored At 4 °C, Recai̇ Kulaksiz, Çi̇ğdem Çebi̇, Ergün Akçay

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to evaluate the effects on sperm motility and abnormality in ram semen extended with skimmed milk (M), sodium citrate (SC), Tris (T), and Bioxcell® (B) after storage in liquid form at 4 °C and in frozen form. Ejaculates were collected from 3 Akkaraman rams by artificial vagina twice a week during the non-breeding season. After pooling, each pooled ejaculate was split into 4 equal aliquots and diluted with skimmed milk (M), sodium citrate (SC), Tris (T), and Bioxcell® (B) extenders. Sperm motility was significantly higher (P < 0.05) in M compared with B, SC, and T on the first and second days (48 h) of storage. With regard to the percentage of total abnormal spermatozoa, the results in M were different from (P < 0.05) from those of SC and T on the first day (24 h) of storage but no different from B. Differences among extenders were found to be significant post-thawing for spermatozoa motility and the percentage of total abnormal spermatozoa. The total abnormality of semen diluted with M was significantly lower than that observed in the other extenders. Consequently, it was found that skimmed milk was better than the other extenders in terms of the sperm parameters evaluated during liquid storage and post-thaw.


Dust And Endotoxin In Laying Hen Dwellings, Kristina Matkovic, Marija Vucemilo, Bara Vinkovic Jan 2012

Dust And Endotoxin In Laying Hen Dwellings, Kristina Matkovic, Marija Vucemilo, Bara Vinkovic

Turkish Journal of Veterinary & Animal Sciences

Only healthy laying hens are capable of producing an average of 280 eggs in 1 year of exploitation. Production of consume eggs takes place in intensive housing systems where the laying hens are still mainly kept in cages under controlled conditions. Technical infrastructure and hygiene quality do not guarantee a production atmosphere completely free from pollutants, including potential pathological risk factors. Laying hens and farm workers are exposed to large quantities of bioaerosols in henhouses. Bioaerosols represent a mixture of different biological particles which can, under certain circumstances, cause health and welfare problems in animals. The most important components are …


Reproductive Performance Of Primiparous And Multiparous Saanen Goats After Laparoscopic Intrauterine Insemination: A Field Study, Recai̇ Kulaksiz, Ali̇ Daşkin Jan 2012

Reproductive Performance Of Primiparous And Multiparous Saanen Goats After Laparoscopic Intrauterine Insemination: A Field Study, Recai̇ Kulaksiz, Ali̇ Daşkin

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to evaluate the reproductive performance of primiparous and multiparous Saanen goats after intrauterine laparoscopic artificial insemination with frozen semen. Twenty-four Saanen goats, divided in 2 groups: group 1 consisted of 11 primiparous goats and group 2 consisted of 13 multiparous goats. Estrus was synchronized by 20 mg fluorogestone acetate (FGA)-impregnated intravaginal sponges and the IM administration of 125 mg of cloprostenol (PGF2\alpha) and eCG (400 IU), 48 h before sponge removal. Intrauterine fixed time artificial insemination (AI) was carried out 55 h after removal of the FGA sponges. Results of the present study indicate …


A Loop-Mediated Isothermal Amplification (Lamp) Assay For Rapid Detection Of Anaplasma Phagocytophilum Infection In Dogs, Chungchen Lee, Yungchang Lin, Chauloong Tsang, Yangtsung Chung Jan 2012

A Loop-Mediated Isothermal Amplification (Lamp) Assay For Rapid Detection Of Anaplasma Phagocytophilum Infection In Dogs, Chungchen Lee, Yungchang Lin, Chauloong Tsang, Yangtsung Chung

Turkish Journal of Veterinary & Animal Sciences

A simple and rapid diagnostic method of Anaplasma phagocytophilum infection was established, employing the loop-mediated isothermal amplification (LAMP) reaction. With 1 set of 4 specific primers targeting the citrate synthase (gltA) gene of A. phagocytophilum, the LAMP assay rapidly amplified the target DNA sequence in a single tube in 1 h, requiring only a water bath for reaction. When visualized by gel electrophoresis, the LAMP products appeared as a ladder-like pattern, with many bands of different sizes from 180 base pairs up to the loading well. The results obtained from testing 32 clinical blood samples of dogs demonstrated that the …


A Punishment-Free, Toilet-Training Protocol For Children With Developmental Disabilities, Chelsea Lynn Pearsall Jan 2012

A Punishment-Free, Toilet-Training Protocol For Children With Developmental Disabilities, Chelsea Lynn Pearsall

All Master's Theses

The present investigation adapted a behaviorally-based toilet-training protocol for use with two male children with developmental disabilities. Positive practice and verbal reprimands were eliminated, and reinforcement, scheduled sits, and a urine alarm were utilized. Data were collected on the number of intoilet urinations, urinary accidents, and self-initiations. Results show that both participants exhibited significant improvement in their toileting skills and met the final success criteria rapidly. These results were maintained through follow-up. Implications for the elimination of punishment procedures in future toilet training protocols are discussed.


The Role Of Notch Receptors And Ligands In Regulation Of Immune Responses, Gerard F. Hoyne Jan 2012

The Role Of Notch Receptors And Ligands In Regulation Of Immune Responses, Gerard F. Hoyne

Health Sciences Papers and Journal Articles

Notch signalling has an important role in the immune system in directing cell fate decisions in a range of diverse cell types. We are beginning to obtain a better understanding of the roles that the different Notch ligands and receptors play in both cellular differentiation of precursor cells and the regulation of immune responses by mature lymphocytes in the periphery. This review will examine the key findings that have emerged in relation to function of Notch in differentiation of T cells, B cells and dendritic cells and how modulation of Notch signalling seems to have potential for therapeutic applications in …


The Phenomenology Of Court-Ordered Treatment: From The Perspective Of Methamphetamine Dependent Adults, Justin Steffener Jan 2012

The Phenomenology Of Court-Ordered Treatment: From The Perspective Of Methamphetamine Dependent Adults, Justin Steffener

Antioch University Dissertations & Theses

This phenomenological study was designed to explore with a sample of methamphetamine dependent adults their perceptions of the process involved in their experiences of court-ordered treatment. The motivation for this study derives from the researcher's wish to unearth ways to better understand and support the needs of adults suffering from addiction. A significant amount of research has already been conducted in regards to the treatment of methamphetamine addiction from the standpoint of quantitative measurements of treatment outcomes, but limited information is presently available from the perspective of the suffers. The stringent selection of the sample was composed of six individuals …


Ride The Wave: A Guide For Implementing Biofeedback In Occupation-Based Interventions In A Rehabilitation Setting, Sarah Averett, Johanna Meister Jan 2012

Ride The Wave: A Guide For Implementing Biofeedback In Occupation-Based Interventions In A Rehabilitation Setting, Sarah Averett, Johanna Meister

Occupational Therapy Capstones

Historical and current research studying EMG biofeedback has shown this method to be an effective adjunct to occupational therapy intervention. Utilizing EMG biofeedback has been shown through research as effective in improving functional gains. The use of biofeedback allows an individual to visualize unseen physiological processes which are unique to each individual and provide better understanding of otherwise unseen functions (Laurenção, Battistella, Moran de Britto, Tsukimoto, & Mayizaki, 2008). An extensive literature review and students’ observations of clinical occupational therapy practice led the investigators to conclude that EMG biofeedback was a viable treatment method which has not been utilized to …


A Lifetime Of Work: A Guide To Health Promotion And Wellness On The Farm, Andrea Hensrud, Gregory Holubok Jan 2012

A Lifetime Of Work: A Guide To Health Promotion And Wellness On The Farm, Andrea Hensrud, Gregory Holubok

Occupational Therapy Capstones

The purpose of this project is to develop a guide to health promotion, wellness and adapting to life changes on the farm from an occupational therapy perspective to enhance quality of life for aging farmers and rural community dwellers. The authors completed a focused literature review on topics related to health promotion, wellness, adapting to life changes, making changes and aging in place. Data was collected through an extensive study of relevant information through professional journals, clinical text books, class discussion and related state and national associations. Upon completion of the review of literature, it was determined that older adults …


Report Of The Voucher And Accreditation Evaluation Project Meeting, Reproductive Health Vouchers Evaluation Team, Population Council Jan 2012

Report Of The Voucher And Accreditation Evaluation Project Meeting, Reproductive Health Vouchers Evaluation Team, Population Council

Reproductive Health

This is a report on a technical advisory meeting that brought together 45 participants from the five country programs being evaluated through the Reproductive Health Voucher and Accreditation (V&A) project, which is implemented by the Population Council with financial support from the Bill and Melinda Gates Foundation. This group met for the first time as a newly emerging “voucher community” to learn from the successes and challenges faced in this early growth phase of emerging V&A programs that deliver maternal and reproductive health services. In addition to standardizing the collection of performance and financing metrics, who would use such data …


Msh2 Acts In Medium-Spiny Striatal Neurons As An Enhancer Of Cag Instability And Mutant Huntingtin Phenotypes In Huntington's Disease Knock-In Mice., Marina Kovalenko, Ella Dragileva, Jason St Claire, Tammy Gillis, Jolene R Guide, Jaclyn New, Hualing Dong, Raju Kucherlapati, Melanie H Kucherlapati, Michelle E Ehrlich, Jong-Min Lee, Vanessa C Wheeler Jan 2012

Msh2 Acts In Medium-Spiny Striatal Neurons As An Enhancer Of Cag Instability And Mutant Huntingtin Phenotypes In Huntington's Disease Knock-In Mice., Marina Kovalenko, Ella Dragileva, Jason St Claire, Tammy Gillis, Jolene R Guide, Jaclyn New, Hualing Dong, Raju Kucherlapati, Melanie H Kucherlapati, Michelle E Ehrlich, Jong-Min Lee, Vanessa C Wheeler

Farber Institute for Neuroscience Faculty Papers

The CAG trinucleotide repeat mutation in the Huntington's disease gene (HTT) exhibits age-dependent tissue-specific expansion that correlates with disease onset in patients, implicating somatic expansion as a disease modifier and potential therapeutic target. Somatic HTT CAG expansion is critically dependent on proteins in the mismatch repair (MMR) pathway. To gain further insight into mechanisms of somatic expansion and the relationship of somatic expansion to the disease process in selectively vulnerable MSNs we have crossed HTT CAG knock-in mice (HdhQ111) with mice carrying a conditional (floxed) Msh2 allele and D9-Cre transgenic mice, in which Cre recombinase is expressed specifically in MSNs …


How Vats Has Changed The Management Of Spontaneous Pneumothorax In The 21st Century, Saulat H. Fatimi, Hashim Muhammad Hanif, Sana Mansoor, Marium Muzaffar Jan 2012

How Vats Has Changed The Management Of Spontaneous Pneumothorax In The 21st Century, Saulat H. Fatimi, Hashim Muhammad Hanif, Sana Mansoor, Marium Muzaffar

Section of Cardiothoracic Surgery

Objective: To determine the outcome of patients having undergone Video Assisted Thoracoscopic Surgery (VATS) for spontaneous pneumothrox in terms of hospital stay, complications and recurrence.
Methods:
The netrospective study included the review of 39 cases who had presented with spontaneous pneumothorax at the Aga Khan University Hospital, Karachi, Pakistan, between January 2001 to November 2008 and had undergone video assisted thoracoscopic surgery (VATS).
Results:
The duration of hospital stay (had a range of 3 to 9 days), and the length of chest tube in place (a range of 2 to 8 days), 2 (5.1%) patients developed recurrence after VATS while …


Dextrocardia With Situs Inversus Totalis: Coronary Artery Bypass Grafting, Salila Hashmi, Mariam Anis, Umer Darr Jan 2012

Dextrocardia With Situs Inversus Totalis: Coronary Artery Bypass Grafting, Salila Hashmi, Mariam Anis, Umer Darr

Section of Cardiothoracic Surgery

Dextrocardia with situs inversus is a rare congenital abnormality involving a left-handed mal rotation of the visceral organs. The incidence of coronary artery disease is the same as that in the general population. Performing coronary artery bypass surgery on patients with dextrocardia poses a more challenging task. It is recommended that the right internal mammary artery be the first choice of graft for the anterior descending artery for a "situs inversus" situation. We report 2 cases of patients with Dextrocardia who developed coronary artery disease and underwent coronary artery bypass grafting. Also mentioned is the slight difference in our technique.


Subclavian Steal Syndrome Secondary To Subclavian Artery Thrombosis In A Patient With Homocysteinemia And Its Successful Treatment, Marium Muzaffar, Hashim Muhammed Hanif, Saulat H. Fatimi, M. Tariq Jan 2012

Subclavian Steal Syndrome Secondary To Subclavian Artery Thrombosis In A Patient With Homocysteinemia And Its Successful Treatment, Marium Muzaffar, Hashim Muhammed Hanif, Saulat H. Fatimi, M. Tariq

Section of Cardiothoracic Surgery

Subclavian steal syndrome (SSS) is a rare condition. It results from subclavian artery (SA) stenosis proximal to the origin of the vertebral artery. It is characterized by cerebral ischaemia with associated symptoms of vertebrobasilar hypoperfusion and/or symptoms of brainstem or arm ischaemia. We describe a case of a 35 year old male who presented with persistent vertigo for two months, blue discoloration and pain in the left fingers for two weeks. A diagnosis of SSS was made and patient was treated with a gortex graft from the arch of the aorta to the second portion of the left subclavian artery. …


Tissue Sampling Methods And Standards For Vertebrate Genomics, Pamela B. Y. Wong, Edward O. Wiley, Warren E. Johnson, Oliver A. Ryder, Stephen J. O'Brien, David Haussler, Klaus-Peter Koepfli, Marlys L. Houck, Polina L. Perelman, Gabriela Mastromonaco, Andrew C. Bentley, Byrappa Venkatesh, Ya-Ping Zhang, Robert W. Murphy, Genome 10k Project Community Of Scientists Jan 2012

Tissue Sampling Methods And Standards For Vertebrate Genomics, Pamela B. Y. Wong, Edward O. Wiley, Warren E. Johnson, Oliver A. Ryder, Stephen J. O'Brien, David Haussler, Klaus-Peter Koepfli, Marlys L. Houck, Polina L. Perelman, Gabriela Mastromonaco, Andrew C. Bentley, Byrappa Venkatesh, Ya-Ping Zhang, Robert W. Murphy, Genome 10k Project Community Of Scientists

Biology Faculty Articles

The recent rise in speed and efficiency of new sequencing technologies have facilitated high-throughput sequencing, assembly and analyses of genomes, advancing ongoing efforts to analyze genetic sequences across major vertebrate groups. Standardized procedures in acquiring high quality DNA and RNA and establishing cell lines from target species will facilitate these initiatives. We provide a legal and methodological guide according to four standards of acquiring and storing tissue for the Genome 10K Project and similar initiatives as follows: four-star (banked tissue/cell cultures, RNA from multiple types of tissue for transcriptomes, and sufficient flash-frozen tissue for 1 mg of DNA, all from …


Long Term Weight Variability In Adults Of Adventist Health Study 1 And 2, Namgyal Lhawang Kyulo Jan 2012

Long Term Weight Variability In Adults Of Adventist Health Study 1 And 2, Namgyal Lhawang Kyulo

Loma Linda University Electronic Theses, Dissertations & Projects

Background: The effect of overweight and obesity on the risk of fatal disease tends to attenuate with age. One plausible explanation is that a proportion of elderly people in the ideal weight category (19 to 25 kg/m ) experienced disease-related weight loss - an effect that will attenuate health risk related to overweight and obesity. One potential approach to controlling for this bias would be to examine fluctuations in weight during the adult lifespan by considering multiple measures of weight or recall of body weight during adulthood. Some of these measures are available in the Adventist Health Study cohorts and …


Onabotulinumtoxin A In The Treatment Of Migraine Headache, Carrie O. Dougherty, Md, Stephen Silberstein, Md Jan 2012

Onabotulinumtoxin A In The Treatment Of Migraine Headache, Carrie O. Dougherty, Md, Stephen Silberstein, Md

Department of Jefferson Headache Center Papers and Presentations

Recent trials have demonstrated that onabotulinumtoxinA is a safe and effective treatment for the prevention of chronic migraine headaches. Although the exact effect of the toxin on the pathophysiology of migraine is not clear, several in-vivo and in-vitro models have shown that onabotulinumtoxinA inhibits the release of neurotransmitters and neuropeptides involved in pain signaling pathways with resulting attenuation of both peripheral and central sensitization in migraine. Limited systemic adverse effects and physician administered treatments that eliminate concerns for patient compliance have made onabotulinumtoxin A an appealing alternative to oral prophylactic medications for migraine. This article is designed to provide an …


Mir-128 Inhibits Tumor Growth And Angiogenesis By Targeting P70s6k1., Zhu-Mei Shi, Jing Wang, Zhiping Yan, Yong-Ping You, Chong-Yong Li, Xu Qian, Yu Yin, Peng Zhao, Ying-Ying Wang, Xie-Feng Wang, Ming-Na Li, Ling-Zhi Liu, Ning Liu, Bing-Hua Jiang Jan 2012

Mir-128 Inhibits Tumor Growth And Angiogenesis By Targeting P70s6k1., Zhu-Mei Shi, Jing Wang, Zhiping Yan, Yong-Ping You, Chong-Yong Li, Xu Qian, Yu Yin, Peng Zhao, Ying-Ying Wang, Xie-Feng Wang, Ming-Na Li, Ling-Zhi Liu, Ning Liu, Bing-Hua Jiang

Kimmel Cancer Center Faculty Papers

MicroRNAs are a class of small noncoding RNAs that function as critical gene regulators through targeting mRNAs for translational repression or degradation. In this study, we showed that miR-128 expression levels were decreased in glioma, and identified p70S6K1 as a novel direct target of miR-128. Overexpression of miR-128 suppressed p70S6K1 and its downstream signaling molecules such as HIF-1 and VEGF expression, and attenuated cell proliferation, tumor growth and angiogenesis. Forced expression of p70S6K1 can partly rescue the inhibitory effect of miR-128 in the cells. Taken together, these findings will shed light to the role and mechanism of miR-128 in regulating …


Table Of Contents Jan 2012

Table Of Contents

Michigan Journal of Public Health

No abstract provided.


Educate Your Patients About Hpv, Constance R. Sharuga, Tabitha Price, Deborah Dotson Jan 2012

Educate Your Patients About Hpv, Constance R. Sharuga, Tabitha Price, Deborah Dotson

ETSU Faculty Works

Excerpt: According to the United States Centers for Disease Control and Prevention (CDC), approximately 20 million Americans are currently infected with human papillomavirus (HPV), and another 6 million will become newly infected each year.


Force Output Comparison Between Six U.S. Collegiate Athletic Teams., Caleb D. Bazyler, George Beckham, Howard Gray, Guy Hornsby, Ashley A. Kavanaugh, Christopher Macdonald, Satoshi Mizuguchi, Michael H. Stone, Michael H. Stone Jan 2012

Force Output Comparison Between Six U.S. Collegiate Athletic Teams., Caleb D. Bazyler, George Beckham, Howard Gray, Guy Hornsby, Ashley A. Kavanaugh, Christopher Macdonald, Satoshi Mizuguchi, Michael H. Stone, Michael H. Stone

ETSU Faculty Works

The aim of the study was to compare allometrically scaled peak force and the force at 250 ms between six U.S. collegiate sport teams using isometric mid-thigh pull. Ninety subjects performed maximum effort of isometric mid-thigh pull to measure force output. The data were averaged within the teams, and statistically compared between teams using one-way ANOVA (p=.01). Significant difference was found that men’s soccer and baseball produced higher allometrically scaled peak force, and men’s soccer, tennis, and baseball produced higher allometrically scaled force at 250 ms. The data indicates that not all sports possess similar strength characteristics because of the …


Predictors Of Clinician Tobacco Intervention Counseling In Six North Carolina Free Clinics, Joe G. Spangler, Eun-Young Song, Jessica Richardson Pockey, Erin L. Sutfin, Donald W. Helme, Cindy Jones, Kristie L. Foley Jan 2012

Predictors Of Clinician Tobacco Intervention Counseling In Six North Carolina Free Clinics, Joe G. Spangler, Eun-Young Song, Jessica Richardson Pockey, Erin L. Sutfin, Donald W. Helme, Cindy Jones, Kristie L. Foley

Communication Faculty Publications

While the poor and the uninsured are at increased risk for tobacco use, up to two thirds of these patients express interest in near-term quitting. Nonetheless, tobacco counseling rates remain low in clinics serving these patients. As part of a larger tobacco intervention project in North Carolina free clinics, we gathered baseline data on patient characteristics in six randomly selected facilities affiliated with the North Carolina Association of Free Clinics. An exit interview was completed by 231 patients; 126 (54%) were tobacco users. Among all patients, 71% had been asked by a clinician about tobacco use in the past 3 …


A Successful Patient Rounding Redesign: Staff Empowerment Blended With A Research Project (Poster), Jody Shigo Rn, Cmsrn, Holly Tavianini Rn, Bsn, Mshsa, Cnrn, Lynn M. Deitrick Rn, Phd, Kathy Baker Mph, Rn, Hannah D. Paxton Bsn, Rn, Michelle D. Flores Jan 2012

A Successful Patient Rounding Redesign: Staff Empowerment Blended With A Research Project (Poster), Jody Shigo Rn, Cmsrn, Holly Tavianini Rn, Bsn, Mshsa, Cnrn, Lynn M. Deitrick Rn, Phd, Kathy Baker Mph, Rn, Hannah D. Paxton Bsn, Rn, Michelle D. Flores

Patient Care Services / Nursing

No abstract provided.