Medicine and Health Sciences Commons^™

Santa Clara Magazine, Volume 53 Number 3, Winter 2012, Santa Clara University

Santa Clara Magazine

18 - MY FIGHT, MY FAITH By Steven Boyd Saum. As head of the CIA, Leon Panetta '60, J.D. '63 restored confidence in the agency and oversaw the mission to find Osama bin Laden. Now, as secretary of defense in an age of budget austerity, he has to make sure the Pentagon doesn't break the bank-and that the nation doesn't break faith with the men and women who serve.

24 - GENERAL JOE By Sam Scott '96. When Joseph Peterson '72 signed up for ROTC as an undergrad, he planned to complete his military service and then move on. Nearly …

Vision, Falls And Fear Of Falling In An Older Irish Population: Findings From The Irish Logitudinal Study On Aging (Tilda), E. Duggan, C. Finucane, H. Cronin, G. Savva, James Loughman, R. A. Kenny

Other

No abstract provided.

The Effect Of Participating In Continuing Optometric Education: A Pilot Study, Claire E. Mcdonnell, Martina Crehan

Other

Purpose: To determine whether participation in two different post graduate optometry workshops resulted in a change in practice for the participants, in their subsequent practice.

Methods: 38 optometrists, who had attended a continuing professional development (CPD) workshop on punctal plugs and lacrimal syringing, were surveyed by email and telephone, between four and thirteen months post workshop, to ascertain if they had made a change to their practice. A second group of 32 optometrists, who had attended a continuing education and training (CET) workshop on binocular vision, were surveyed by email, telephone and postal mail between six and nine months post …

Epidemiology Of Psychiatric Disorders Across The Lifespan - Course Syllabus 2011-2012

Teaching Materials

No abstract provided.

Patient Safety, Quality Management And Quality Improvement - Course Syllabus

Teaching Materials

No abstract provided.

Introduction To Dissemination And Implementation Science - Course Syllabus 2011-2012

Teaching Materials

No abstract provided.

Introduction To Epidemiology - Course Syllabus 2011-2012

Teaching Materials

No abstract provided.

Libro De Actividades Por El Mes Nacional De La Salud Dental Infantil [Spanish Language Version: National Children's Dental Health Month Activity Book] (2012), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

Crohn’S Disease: A Brief And Elementary Overview, Dayne Sullivan

The Corinthian

Crohn’s disease (CD) is defined by chronic inflammation of an isolated portion of the gastrointestinal track. Frequently, the site of inflammation is the proximal portion of the colon, or less commonly, the terminal ileum. Other names for the disease frequently reported in medical literature and research include regional enteritis and granulomatous colitis. The specific etiology of CD is idiopathic but there are several widely accepted theories.

An Hsi Report: Industrial Farm Animal Production And Livestock Associated Mrsa (Methicillin Resistant Staphylococcus Aureus), Humane Society International

HSI REPORTS

Staphylococcus aureus is a leading cause of bacterial infection and is increasingly found to be resistant to antibiotic therapy. A newly described type of Methicillin Resistant Staphylococcus aureus carried by farm animals, Livestock Associated MRSA (LA-MRSA), is now causing infections in humans with and without direct livestock contact. A reduction in the non-therapeutic use of antibiotics in feed would likely reduce the capacity of industrial animal agriculture to continue to create, disseminate, and perpetuate a large reservoir of LA-MRSA on a global scale, but more fundamental changes in the way animals are raised for food may be necessary forestall a …

Puppy Buyer Complaints: A Five-Year Summary, 2007‐2011, The Humane Society Of The United States

PUPPY MILL REPORTS

The Humane Society of the United States receives complaints about sick puppies on a daily basis. Over a five-year period (2007-2011), our puppy mills campaign received 2,479 puppy buyer complaints. The complaint came to The HSUS via our website complaint form (www.humanesociety.org/puppycomplaint), by email, and through our puppy mills tip line. Buyers complained about sick puppies sold by a variety of sources, including pet stores, breeders (both in person and online), or middleman dealers (sometimes known as brokers). Unsatisfied buyers contact The HSUS for many reasons; some are seeking information about how to pursue their consumer complaint, others …

Veterinary Problems In Puppy Mill Dogs, The Humane Society Of The United States

PUPPY MILL REPORTS

Dogs in puppy mills often suffer from an array of painful and potentially life-shortening veterinary problems due to overcrowded, unsanitary conditions and the lack of proper oversight or veterinary care. Conditions common to puppy mills, such as the use of stacked, wire cages to house more animals than a given space should reasonably hold, as well as constant exposure to the feces and urine of other dogs, make it difficult for dogs to avoid exposure to common parasites and infectious diseases. In addition, a lack of regular, preventive veterinary care, clean food and water, basic cleaning and grooming, and careful …

Rational Engagement, Emotional Response, And The Prospects For Moral Progress In Animal Use “Debates”, Nathan Nobis

Animal Welfare Collection

This chapter is designed to help people rationally engage moral issues regarding the treatment of animals, specifically in experimentation, research, product testing, and education. Little “new” philosophy is offered here, strictly speaking. New arguments are unnecessary to help make progress in how people think about these issues. What is needed are improved abilities to engage the arguments already on the table, for example, stronger skills at identifying and evaluating the existing reasons given for and against conclusions on the morality of various uses of animals. To help improve these abilities, this chapter sets forth a set of basic but powerful …

Construct Validity Of Animal-Assisted Therapy And Activities: How Important Is The Animal In Aat?, Lori Marino

Animal-Assisted Therapy Collection

Animal-assisted therapy and animal-assisted activities involve a nonhuman animal as a key therapeutic agent in some kind of intervention that may range from highly specified, as in AAT, to more casual, as in AAA. In this review I address the question: How important is the animal in animal therapy? In other words, does the recent literature strongly support the notion that a live animal, as opposed to another novel stimulating component, is specifically necessary for therapeutic success. Two meta-analyses and 28 single empirical studies were reviewed in order to address this issue. I conclude that the effects of AAT and …

Clinical Anesthesia And Analgesia In Fish, Lynne U. Sneddon

Veterinary Science and Medicine Collection

Fish have become a popular experimental model and companion animal, and are also farmed and caught for food. Thus, surgical and invasive procedures in this animal group are common, and this review will focus on the anesthesia and analgesia of fish. A variety of anesthetic agents are commonly applied to fish via immersion. Correct dosing can result in effective anesthesia for acute procedures as well as loss of consciousness for surgical interventions. Dose and anesthetic agent vary between species of fish and are further confounded by a variety of physiological parameters (e.g., body weight, physiological stress) as well as environmental …

Characterisation Of Chemosensory Trigeminal Receptors In The Rainbow Trout, Oncorhynchus Mykiss: Responses To Chemical Irritants And Carbon Dioxide, Jessica J. Mettam, Catherine R. Mccrohan, Lynne U. Sneddon

Veterinary Science and Medicine Collection

Trigeminally innervated, mechanically sensitive chemoreceptors (M) were previously identified in rainbow trout, Oncorhynchus mykiss, but it is not known whether these receptors are responsive only to noxious, chemical irritants or have a general chemosensory function. This study aimed to characterise the stimulus–response properties of these receptors in comparison with polymodal nociceptors (P). Both P and M gave similar response profiles to acetic acid concentrations. The electrophysiological properties were similar between the two different afferent types. To determine whether the receptors have a nociceptive function, a range of chemical stimulants was applied to these receptors, including non-noxious stimuli such as ammonium …

Pursuing Medawar’S Challenge For Full Replacement, Martin Stephens

Experimentation Collection

In 1969, Nobel Prize-winning scientist Peter Medawar predicted that scientific innovation would someday fully replace the use of animals in biomedical research. Medawar correctly forecast the leveling off and subsequent decline in animal use in the last quarter of the 20th century – a period of remarkable innovation in the life sciences. A 2007 report by the U.S. National Academy of Sciences, Toxicity Testing in the 21st Century, proposed a strategy that is likely to replace all routine animal use in toxicology with innovative methods within one to two decades. Replacing animal use throughout biomedical research is more challenging given …

Prevalence Of Antibodies To Canine Parvovirus And Distemper Virus In Wolves In The Canadian Rocky Mountains, Brynn Nelson, Mark Hebblewhite, Vanessa Ezenwa, Todd Shury, Evelyn H. Merrill, Paul C. Paquet, Fiona Schmiegelow, Dale Selp, Geoff Skinner, Nathan Webb

Epidemiology Collection

Wild carnivores are often exposed to diseases via contact with peridomestic host species that travel through the wildland-urban interfaces. To determine the antibody prevalences and relationships to human activity for two common canid pathogens, we sampled 99 wolves (Canis lupus) from 2000 to 2008 for antibodies to canine parvovirus (CPV) and canine distemper virus (CDV) in Banff and Jasper National Parks and surrounding areas of the Canadian Rockies. This population was the source for wolves reintroduced into the Northern Rockies of the US. Of 99 wolves sampled, 94 had detectable antibody to CPV (95%), 24 were antibody-positive for CDV (24%), …

A Roadmap For The Development Of Alternative (Non-Animal) Methods For Systemic Toxicity Testing, David Basketter, Harvey Clewell, Ian Kimber, Annamaria Rossi, Bas Blaauboer, Robert Burrier, Mardas Daneshian, Chantra Eskes, Alan Goldberg, Nina Hasiwa, Sebastian Hoffmann, Joanna Jaworska, Thomas B. Knudsen, Robert Landsiedel, Marcel Leist, Paul Locke, Gavin Maxwell, James Mckim, Emily Mcvey, Gladys Ouédraogo, Grace Patlewicz, Olavi Pelkonen, Erwin Roggen, Costanza Rovida, Irmela Ruhdel, Michael Schwarz, Andreas Schepky, Greet Schoeters, Nigel Skinner, Kerstin Trentz, Marian Turner, Philippe Vanparys, James Yager, Joanne Zurlo, Thomas Hartung

Biomedical Research and Alternative Methods Collection

Systemic toxicity testing forms the cornerstone for the safety evaluation of substances. Pressures to move from traditional animal models to novel technologies arise from various concerns, including: the need to evaluate large numbers of previously untested chemicals and new products (such as nanoparticles or cell therapies), the limited predictivity of traditional tests for human health effects, duration and costs of current approaches, and animal welfare considerations. The latter holds especially true in the context of the scheduled 2013 marketing ban on cosmetic ingredients tested for systemic toxicity. Based on a major analysis of the status of alternative methods (Adler et …

Mammary Cell Activity And Turnover In Dairy Cows Treated With The Prolactin-Release Inhibitor Quinagolide And Milked Once Daily, M. Boutinaud, V. Lollivier, L. Finot, R. M. Bruckmaier, P. Lacasse

Physiology Collection

To assess the regulation of mammary cell activity, survival, and proliferation by prolactin (PRL), 5 Holstein cows in early lactation received daily i.m. injections of 1 mg of quinagolide, a suppressor of PRL release, for 9 wk, whereas 4 control cows received the vehicle (water) only. During the last week of treatment, one udder half was milked once a day (1×) and the other twice a day (2×). Mammary biopsies were harvested 1 wk before and 4 and 8 wk after the start of quinagolide treatment. The quinagolide injections reduced milk yield and resulted in lower levels of κ-casein and …

Fall Risk Assessments Based On Postural And Dynamic Stability Using Inertial Measurement Unit, Jian Liu, Xiaoyue Zhang, Thurmon E. Lockhart

Computer Sciences and Electrical Engineering Faculty Research

Objectives: Slip and fall accidents in the workplace are one of the top causes of work related fatalities and injuries. Previous studies have indicated that fall risk was related to postural and dynamic stability. However, the usage of this theoretical relationship was limited by laboratory based measuring instruments. The current study proposed a new method for stability assessment by use of inertial measurement units (IMUs).

Methods: Accelerations at different body parts were recorded by the IMUs. Postural and local dynamic stability was assessed from these measures and compared with that computed from the traditional method. Results: The results demonstrated: 1) …

Hispanic Maternal And Children's Perceptions Of Neighborhood Safety Related To Walking And Cycling, Norma Olvera, Dennis W. Smith, Chanam Lee, Jian Liu, Jay Lee, Stephanie Kellam, Jun-Hyun Kim

Computer Sciences and Electrical Engineering Faculty Research

This study examined neighborhood safety as perceived by children (mean age=10 years) and their mothers, and its association with children's physical activity. For all eight safety items examined, children perceived their environment as less dangerous than mothers (p<0.05). None of the multiple regression models predicting children's physical activity by safety perceptions were significant (p>0.10). The maternal perception model explained the highest percentage of variance (R²=0.26), compared to the children's perception model (R²=0.22). Findings suggest that future studies should explore relations between self-reported and objectively measured safety barriers to Hispanic youth walking and cycling.

Design And Experimental Validation Of Continuous Dna Separation Using Itp-Based Microfluidic Device, Nora C. M. Goscinski, Mary E. Rosa, Elizabeth K. Wheeler, Maxim Shusteff

Chemistry and Biochemistry

We have demonstrated a chip-based microfluidic device suitable for rapid and high-throughput DNA separation and purification for downstream analysis. The glass-based device incorporates a transverse free-flow isotachophoresis (tFF-ITP) that overcomes the volume limitations of CE approaches, and allows continuous sample processing in contrast to batch-mode solid-phase extraction (SPE). The device is able to focus DNA at flow rates up to 100 uL/min, and sample conductivity up to 2 mS/cm. Downstream of the chip, 30-40% of DNA from the input sample is recovered as a result of ITP focusing, and preliminary results indicate that this design is able to purify DNA …

Effects Of Lean Beef Supplementation On Iron Status, Body Composition And Performance Of Collegiate Distance Runners, Danielle E. Burke, Jocelyn V. Johnson, Matthew D. Vukovich, Kendra K. Kattelmann 6884045

Health and Nutritional Sciences Faculty Publications

Iron deficiency is prevalent among endurance athletes, particularly females. Low iron may compromise oxygen delivery and physical performance. Vegetarianism, desire for convenience, and perceived health risks associated with red meat contribute to low bioavailable iron intakes. The purpose of this study was to examine if lean beef supplementation would maintain iron status, improve body composition and increase performance of distance runners after 8 weeks. Twenty-eight (14 female) Division-I cross-country runners were stratified by iron status, use of iron supplements, and gender, and randomized into a control (n = 14) and intervention group. All participants maintained their typical diet and consumed …

The College Of Pharmacy, South Dakota State University

Jackrabbits Script and Scope (Formerly called College of Pharmacy and Allied Health Professions Magazine)

[Page] 2 A rural residency Liebe Drug is teaming with the College to create a rural residency program.
[Page] 4 A small-town summer Program putting P2 students in six communities this summer.
[Page] 6 Good things in small packages Rural pharmacies face serious challenges.
[Page] 8 Changing landscape Visiting dean foresees new roles for pharmacist, the industry.
[Page] 10 Jim Roeman After forty-seven years, the cornerstone of Rock Rapids, Iowa, plans to turn a corner.
[Page] 11 Brian Kaatz The 1974 grad and former dean is named Alumnus of the Year by the College.
[Page] 12 Alex VanOverschelde P2 student …

Evaluating Psychiatric Patients’ Attitudes Of A Shared Electronic Medical Record, Edward R. Norris Md, Fapa, Fapm, Julia R. Correll Ba, Jamie Bongiovi Lcsw, David Dylewski Ms, Gail Stern Msn, Michael Kaufmann Md

Department of Psychiatry

No abstract provided.

Charcot Foot Ulceration, Katelin Sievert

Physical Therapy Scholarly Projects

This case report follows the treatment of a 64 year old male with a Charcot foot ulceration of the right foot. The study was conducted to assess the outcome of wound care to the stage three pressure ulcer and the use of a Total Contact Cast (TCC) in the treatment of the Charcot foot ulceration, as well as to present more awareness to the medical field on Charcot foot pathology and diagnosis. The study was conducted over a 16 week time period. After 15 sessions with the patient, the results showed that wound care, the use of a TCC, and …

Effect Of Frontal Plane Foot Position On Lower Extremity Muscle Activation And Limb Positioning In A Single Leg Squat, Marissa N. Laddusaw

Physical Therapy Scholarly Projects

Purpose/Background: This goal of this study was to reach a bottom up understanding of ACL injury occurrence. Subtalar position during single leg stance may affect the muscles associated with the knee joint and promote ACL injury. The muscle activity of six muscles of the leg, thigh, and hip were analyzed during a single leg squat with the foot on surfaces of 10 degrees decline, five degrees decline, neutral, and 5 degrees incline, and 10 degrees incline.

Methods: Seventeen healthy participants between the ages of 18 and 30 performed five rhythmically timed repetitions of single leg squats on surfaces of 10 …

Diagnosis Of Porcine Teschovirus Encephalomyelitis In The Republic Of Haiti, Ming Y. Deng, Max Millien, Rodney Jacques-Simon, J. Keith Flanagan, Alexa J. Bracht, Consuelo Corrillo, Roger W. Barrette, Andrew Fabian, Fawzi Mohamed, Karen Moran, Jessica Rowland, Sabrina L. Swenson, Melinda Jenkins-Moore, Leo Koster, Bruce V. Thomsen, Gregory Mayr, Dave Pyburn, Paula Morales, John Shaw, Thomas Burrage, William White, Michael T. Mcintosh, Samia Metwally

Zoonotics and Wildlife Disease: Publications

In February and March 2009, approximately 1,500 backyard pigs of variable age became sick, and approximately 700 of them died or were euthanized in the Lower Artibonite Valley and the Lower Plateau of the Republic of Haiti. The main clinical sign was posterior ataxia followed by paresis and/or paralysis on the second or third day of illness. No gross lesions were observed at postmortem examinations. The morbidity and mortality were approximately 60% and 40%, respectively. Diagnostic samples (whole blood, brain, tonsil, lymph nodes, spleen, and lung) were negative for Classical swine fever virus and African swine fever virus. Porcine …

Crystal Structures Of Human Pyridoxal Kinase In Complex With The Neurotoxins, Ginkgotoxin And Theophylline: Insights Into Pyridoxal Kinase Inhibition, Amit Gandhi, Jigar V. Desai, Mohini S. Ghatge, Martino L. Di Salvo, Stefano Di Biase, Richmond Danso-Danquah, Faik N. Musayev, Roberto Contestabile, Verne Schirch, Martin A. Safo

Medicinal Chemistry Publications

Several drugs and natural compounds are known to be highly neurotoxic, triggering epileptic convulsions or seizures, and causing headaches, agitations, as well as other neuronal symptoms. The neurotoxic effects of some of these compounds, including theophylline and ginkgotoxin, have been traced to their inhibitory activity against human pyridoxal kinase (hPL kinase), resulting in deficiency of the active cofactor form of vitamin B6, pyridoxal 5′-phosphate (PLP). Pyridoxal (PL), an inactive form of vitamin B6 is converted to PLP by PL kinase. PLP is the B6 vitamer required as a cofactor for over 160 enzymatic activities essential in primary and secondary metabolism. …