Medicine and Health Sciences Commons^™

Ketamine As An Adjunct For The Long-Term Sedation And Analgesia Of A Patient With A Left Ventricular Assist Device (Lvad) And An Open Chest, Avni Gupta, Charles S. Kato, Eugene R. Viscusi

Department of Anesthesiology Faculty Papers

Conclusion:

A multimodal sedative and analgesic regimen that incorporates ketamine offers important therapeutic advantages in select patients who require very high doses of opioids and benzodiazepines, but warrants futher study.

Single-Chain Vαvβ T Cell Receptors Function Without Mispairing With Endogenous Tcr Chains1, David H. Aggen, Adam S. Chervin, Thomas M. Schmitt, Boris Engels, Jennifer D. Stone, Sarah A. Richman, Kurt H. Piepenbrink, Brian M. Baker, Philip D. Greenberg, Hans Schreiber, David M. Kranz

Food for Health: Publications

Transduction of exogenous T cell receptor (TCR) genes into patients’ activated peripheral blood T cells is a potent strategy to generate large numbers of specific T cells for adoptive therapy of cancer and viral diseases. However, the remarkable clinical promise of this powerful approach is still being overshadowed by a serious potential consequence: mispairing of the exogenous TCR chains with endogenous TCR chains. These “mixed” heterodimers can generate new specificities that result in graft-versus-host reactions. Engineering TCR constant regions of the exogenous chains with a cysteine promotes proper pairing and reduces the mispairing, but, as we show here, does not …

Quality Of Care In Ambulatory Surgical Centers, Gina L. Campanella Jd,Mha

Petersheim Academic Exposition

No abstract provided.

Development Of A Statement On Autonomous Practice: Practice Committee, Section On Geriatrics, Jason Hardage, Stacey Zeigler, Jennifer Blackwood, Tamara Gravano, Greg Hartley, Jill Heitzman, Joe Libera, Ken Miller

Physical Therapy Faculty Research

Vision 2020 is the official vision statement of the American Physical Therapy Association (APTA). Drafted by the APTA House of Delegates in 2000, this statement contains 6 elements: autonomous physical therapist practice, direct access, Doctor of Physical Therapy and lifelong education, evidence-based practice, practitioner of choice, and professionalism. Autonomous practice has been operationally defined by the APTA primarily through its characteristics: “Physical therapists accept the responsibility to practice autonomously and collaboratively in all practice environments to provide best practice to the patient/client. Autonomous physical therapist practice is characterized by independent, self-determined, professional judgment and action.” The Section on Geriatrics has …

Cardiovascular Pharmacogenomics: Current Status And Future Directions—Report Of A National Heart, Lung, And Blood Institute Working Group, Kiran Musunuru, Dan M. Roden, Robin Boineau, Michael R. Bristow, Timothy A. Mccaffrey, Christopher Newton-Cheh, Dina N. Paltoo, Yves Rosenberg, Jay G. Wohlgemuth, Issam Zineh, Ahmed A.K. Hasan

Medicine Faculty Publications

No abstract provided.

Asymmetric Directional Microphone Fittings For Individuals With An Asymmetric Hearing Loss, Jessica White

Doctoral Dissertations

The present study investigated the effects of asymmetric directional microphone fittings on participants' acceptance of background noise and speech understanding in noise abilities. Thirteen adult, bilateral hearing aid users or non-hearing aid users with bilateral asymmetrical sensorineural hearing loss were fit binaurally with four different microphone conditions (i.e., bilateral omnidirectional, asymmetric directional poorer ear, asymmetric directional better ear, and bilateral directional) and monaurally with two microphone conditions (i.e., unilateral directional better ear and unilateral omnidirectional better ear). The amplification used was a pair of Siemens Intuis directional behind-the-ear hearing aids and comply earmolds.

The results indicated speech understanding in noise …

Effects Of Cardiovascular Exercise On The Selection Of Preferred Listening Levels Using Ipods, Jessica Leigh Ann Newman

Doctoral Dissertations

The present project evaluated the effect of cardiovascular exercise on the selection of preferred listening levels using iPods. The participants in this study included 15 Louisiana Tech University students ranging in age from 19 and 30 years. The inclusion criteria for participants was as follows: (1) normal hearing sensitivity; (2) no known neurological, cognitive, or otologic impairment; (3) removal from excessive noise for at least 48 hours prior to testing; and (4) endurance in running on a treadmill for the duration of ten minutes.

Pre-test audiometric thresholds and distortion product otoacoustic emissions (DPOAEs) were obtained in a sound treated booth. …

What's Happening: April, 2012, Maine Medical Center

What's Happening

No abstract provided.

Self-Harm And Suicidal Behaviors In Hong Kong Adolescents: Prevalence And Psychosocial Correlates, Daniel T. L. Shek, Lu Yu

Pediatrics Faculty Publications

The present paper examined the prevalence and psychosocial correlates of adolescent deliberate self-harm (DSH) and suicidal behavior in a representative sample of 3,328 secondary school students in Hong Kong. With reference to the previous year, 32.7% of the students reported at least one form of DSH, 13.7% of the respondents had suicide thoughts, 4.9% devised specific suicidal plans, and 4.7% had actually attempted suicide. Adolescent girls had significantly higher rates of DSH and suicidal behavior than did adolescent boys. Having remarried parents was related to an increased likelihood of DSH and suicide. While high levels of family functioning, overall positive …

Effects Of Leptin Replacement Alone And With Exendin-4 On Food Intake And Weight Regain In Weight-Reduced Diet-Induced Obese Rats, Roger Reidelberger, Alvin Haver, Prasanth K. Chelikani, Bettye Apenteng, Curtis Perriotte-Olson, Krista Anders, Sharalyn Steenson, James E. Blevins

United States Public Health Resources

Reidelberger R, Haver A, Chelikani PK, Apenteng B, Perriotte-Olson C, Anders K, Steenson S, Blevins JE. Effects of leptin replacement alone and with exendin-4 on food intake and weight regain in weight-reduced diet-induced obese rats. Am J Physiol Endocrinol Metab 302: E1576–E1585, 2012. First published April 17, 2012; doi:10.1152/ajpendo.00058.2012.—Weight loss in obese humans produces a relative leptin deficiency, which is postulated to activate potent orexigenic and energy conservation mechanisms to restrict weight loss and promote weight regain. Here we determined whether leptin replacement alone or with GLP-1 receptor agonist exendin-4 attenuates weight regain or promotes greater weight loss in weight-reduced …

Tailoring The Immune Response By Targeting C-Type Lectin Receptors On Alveolar Macrophages Using “Pathogen-Like” Amphiphilic Polyanhydride Nanoparticles, Ana V. Chavez-Santicoy, Rajarshi Roychoudhury, Nicola L.B. Pohl, Michael J. Wannemeuhler, Balaji Narasimhan, Amanda E. Ramer-Tait

Amanda Ramer-Tait Publications

C-type lectin receptors (CLRs) offer unique advantages for tailoring immune responses. Engagement of CLRs regulates antigen presenting cell (APC) activation and promotes delivery of antigens to specific intracellular compartments inside APCs for efficient processing and presentation. In these studies, we have designed an approach for targeted antigen delivery by decorating the surface of polyanhydride nanoparticles with specific carbohydrates to provide pathogen-like properties. Two conserved carbohydrate structures often found on the surface of respiratory pathogens, galactose and di-mannose, were used to functionalize the surface of polyanhydride nanoparticles and target CLRs on alveolar macrophages (AMϕ), a principle respiratory tract APC. Co-culture of …

Malnutrition In Young Pakistani Children, Shela Akbar Ali Hirani

School of Nursing & Midwifery

Background: Pakistan is a developing country with the second highest infant and child mortality rate in South Asia. In this region, malnutrition underlies much of the high infant and under five child morbidity and mortality rates. Although struggle to tackle the issue of malnutrition among young Pakistani children has been going on since many decades, till yet a realistic solution for this growing problem has not been found.

Objective: This paper aims at reviewing literature to analyse the biological, maternal, socio-cultural, environmental, and politico-economical determinants of malnutrition among young children in Pakistan so that need based interventions can …

2012 Cardinal Athletics Vol.6, Issue 2, Spring, Otterbein University

Cardinal Athletics Newsletter

The Cardinal Athletics Newsletter is published three times per year and covers all athletic activities at the Otterbein University.

Section Abstracts: Medical Science

Virginia Journal of Science

Abstracts of the Medical Science Section for the 90th Annual Meeting of the Virginia Academy of Science, May 23-25, 2012, Norfolk State University, Norfolk Virginia.

Library Poster For Quiet Contemplation, Education Services

Library Posters

Library poster for quiet contemplation.

Loma Linda University Dentistry - Volume 23, Number 1, Loma Linda University School Of Dentistry

Articulator (Dentistry)

Contents:

12 | Class of '62 Cruises Canada
14 | Officer Ships Out
17 | Students Meet State
22 | Desert Dental Hygiene
25 | Interdisciplinary Treatment
29 | Perio Program Celebrates
43 | Dr. Lloyd Baum's Long Shadow

Sir William Osler, M.D., C.M., Jonathan Sarik, B.S., Charles J. Yeo, Md, Pinckney J. Maxwell, Iv, Md

Department of Surgery Gibbon Society Historical Profiles

Sir William Osler impacted medical education and the practice of medicine like few other physicians. As a writer, he authored nearly 1500 publications and lent his name to numerous eponyms. As a teacher he educated vast numbers of students and through his legacy impacted countless more. Sir William Osler (Fig. 1) epitomized what a physician should be throughout his professional life.

The Appropriateness Of Long-Term Opioids To Treat Chronic Back Pain, Thomas Watanabe, Michael Salino, Adam Schreiber

Department of Rehabilitation Medicine Faculty Papers

Point/Counterpoint Case Scenario: A 55-year old man presents to a pain clinic upon referral from his primary care physician. His symptom is axial low back pain. His pain started approximately 1 year earlier without a specific inciting event. He denies radiation of pain into the lower extremities. There is no bowel or bladder involvement. There is no directional preference. He reports pain "all the time," with minimal specific exacerbating or relieving factors. There is no medical-legal involvement. His medical history is significant for hypertension, hypercholesterolemia, obesity, and sleep apnea. He is a divorced father of 2 adult children. He is …

Psychostimulant Drug Abuse And Personality Factors In Medical Students, Joshua T. Buchner, Md, Duc M. Vu, Md, Mohammadreza Hojat

CRMEHC Faculty Papers

Purpose:

This study was designed to examine the prevalence of psychostimulant drug abuse among medical students and to test the hypothesis that medical students who use psychostimulant drugs for non-medical reasons are characterized by a sensation seeking and aggressive-hostility personality and exhibit lower empathy.

Stroke Education In The Chinese Community: A Nurse Resident Project, Laura Beans, Bsn, Rn, Roisin Harvey, Bsn, Rn, Jonathan Lee, Bsn, Rn, David Lincul, Bsn, Rn, Gina Ramos, Bsn, Rn, Jodi Schantz, Bsn, Rn

Department of Nursing papers and presentations

Objectives:

To educate an urban Chinese community by creating a stroke prevention program that increases awareness of the disease.

To educate an urban Chinese community about stroke risk factors, stroke warning signs, and how to reduce modifiable stroke risk factors.

Geriatric Trauma Patients In The Emergency Department: Length Of Stay, Intensity Of Care, And Post Ed Destination", Elanor Gates, Doris Warner, Meg Bourbonniere, Patricia Williams

Department of Nursing papers and presentations

Background & Purpose: Research on emergency department length of stay (EDLOS) suggests that increased LOS may result in worse patient outcomes and increased overall LOS. Additional research suggests that increased age may not only result in lower intensity of care for some patients but might also increase EDLOS. For geriatric trauma patients, intensity of care and EDLOS may be different from non-geriatric patients. Given the nature of geriatric traumatic injury, it is important to understand if improvements can be made in geriatric trauma services.

Study/Project Design: A retrospective descriptive study utilizing the hospital’s trauma registry data was completed, including patient …

New Library Catalog-Eos, Education Services

Library Posters

Library poster for new library catalog-EOS.

Oral Microbial Biofilm Stimulation Of Epithelial Cell Responses, Rebecca Peyyala, Sreenatha S. Kirakodu, Karen F. Novak, Jeffrey L. Ebersole

Center for Oral Health Research Faculty Publications

Oral bacterial biofilms trigger chronic inflammatory responses in the host that can result in the tissue destructive events of periodontitis. However, the characteristics of the capacity of specific host cell types to respond to these biofilms remain ill-defined. This report describes the use of a novel model of bacterial biofilms to stimulate oral epithelial cells and profile select cytokines and chemokines that contribute to the local inflammatory environment in the periodontium. Monoinfection biofilms were developed with Streptococcus sanguinis, Streptococcus oralis, Streptococcus gordonii, Actinomyces naeslundii, Fusobacterium nucleatum, and Porphyromonas gingivalis on rigid gas-permeable contact lenses. Biofilms, as well as planktonic cultures …

Genome-Wide Patterns Of Arabidopsis Gene Expression In Nature, Christina L. Richards, Ulises Rosas, Joshua A. Banta, Naeha Bhambra, Michael D. Purugganan

Integrative Biology Faculty and Staff Publications

Organisms in the wild are subject to multiple, fluctuating environmental factors, and it is in complex natural environments that genetic regulatory networks actually function and evolve. We assessed genome-wide gene expression patterns in the wild in two natural accessions of the model plant Arabidopsis thaliana and examined the nature of transcriptional variation throughout its life cycle and gene expression correlations with natural environmental fluctuations. We grew plants in a natural field environment and measured genome-wide time-series gene expression from the plant shoot every three days, spanning the seedling to reproductive stages. We find that 15,352 genes were expressed in the …

Community Mental Health Services: A Way Forward To Rehabilitate Chronic Mentally Ill Client., Ambreen Tharani, Salima Farooq, Anila Naveed

School of Nursing & Midwifery

Schizophrenia and other mental illnesses produce devastating effects on a clients' personal and psychosocial wellbeing. Besides the sufferer, it has irrevocable impacts on the lives of their loved ones. With advancement in the treatment modalities, researches have proven that hospital based care and psychotropic drugs are not the sole solution in managing the client symptoms. Deinstitutionalization is the paradigm shift from hospital based to community based care model that allows client/s to spend rest of their lives in the community setting. A well-structured community care based programme that focuses on psychosocial interventions has significant contribution in treatment and rehabilitation of …

University Of New England’S College Of Osteopathic Medicine 2012 Dean's Research Fellowship Recipients, University Of New England College Of Osteopathic Medicine

Peter Morgane Research Fellowships

2012 recipients of the University of New England College of Osteopathic Medicine's Peter Morgane Research Fellowship (known then as the Dean’s Research Fellowship).

Member And Non-Member Perceptions Of The Cdpaanys Outreach And Education Grant, Kenneth B. Holmes

MPA Capstone Projects 2006 - 2015

The New York State Department of Health (DOH) recently began funding a grant to the CDPANNYS, on organization whose members focus on the delivery of self-directed home care. This grant funds outreach and education to stakeholders concerning the statewide availability of the Consumer Directed Personal Assistance Program (CDPAP), a home care program for Medicaid eligible New Yorkers. CDPAANYS is an inter-organizational membership organization, and its 14 members do not cover all of the New Yorks 62 counties. However, the DOH grant required CDPAANYS to conduct statewide outreach that promotes both member organization and non-members. This research study examined how the …

Gsbs News, Spring 2012, Graduate School Of Biomedical Sciences, University Of Texas Health Science Center At Houston/M.D. Anderson Cancer Center

GSBS News

No abstract provided.

Bluetooth Headset Specifications And Its Possible Effects On Hearing Loss, Kristi Ann Anderson

Doctoral Dissertations

The purpose of this study was to determine Bluetooth headset specifications and its potential effects on hearing loss. The following research questions were assessed: (1) what is the maximum peak output of various Bluetooth headsets coupled to a cellular phone; (2) what is the average output of various Bluetooth headsets coupled to a cellular phone; and (3) what is the frequency response of various Bluetooth headsets coupled to a cellular phone? Sixteen Bluetooth headset devices of various manufacturers were used for this study. Bluetooth headsets used for this study were determined by consumer demands and lack of output specifications provided …

The Effects Of Background Noise On Distortion Product Otoacoustic Emissions And Hearing Screenings, Amy E. Hollowell

Doctoral Dissertations

Hearing screenings are an important tool for identifying children who have, or are at risk for hearing loss in the schools. In light of a body of evidence that demonstrates the effectiveness of objective screening measures, such as otoacoustic emissions (OAEs), the American Speech Language and Hearing Association (ASHA) recommends traditional pure tone audiometric screening as the tool of choice for hearing screenings in the schools. Pure tone audiometric screenings conducted in the schools are problematic for a number of reasons, but the most significant is the presence of background noise which is routinely encountered. The main purpose of the …