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Articles 5251 - 5280 of 6767
Full-Text Articles in Medicine and Health Sciences
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Turkish Journal of Medical Sciences
The effect of 50 Hz electric field (EF) on developing neural tissues is not known. We aimed to determine whether there would be any oxidative stress effect of 50 Hz EF on developing spinal cord tissues of pup rats by evaluating malondialdehyde (MDA), nitric oxide (NO) levels, and antioxidant enzyme activities such as superoxide dismutase (SOD) and catalase (CAT) measurement. Materials and methods: In the prenatal+postnatal group, the pregnant rat was exposed to continuous EF at 50 Hz 10 kV/s until delivery. Then the female pups of this group (n = 7) were exposed to EF at the same doses …
Efficacy Of Hyaluronic Acid - Carboxymethyl Cellulose Membrane (Seprafilm®) And Polylactic Acid Barrier Film (Surgiwrap™) For The Prevention Of Adhesions After Thyroid Surgery: An Experimental Model, Gökhan Çi̇pe, Hakan Mustafa Köksal, Sadik Yildirim, Mustafa Fevzi̇ Celayi̇r, Adi̇l Baykan
Efficacy Of Hyaluronic Acid - Carboxymethyl Cellulose Membrane (Seprafilm®) And Polylactic Acid Barrier Film (Surgiwrap™) For The Prevention Of Adhesions After Thyroid Surgery: An Experimental Model, Gökhan Çi̇pe, Hakan Mustafa Köksal, Sadik Yildirim, Mustafa Fevzi̇ Celayi̇r, Adi̇l Baykan
Turkish Journal of Medical Sciences
Adhesions occurring after initial surgery increase complications in secondary thyroid operations. Therefore use of anti-adhesive barriers may reduce complication rates of secondary thyroid operations. In this study, we investigated the efficacy of hyaluronic acid-carboxymethyl cellulose membrane (HA-CMC, Seprafilm®) and polylactic acid barrier film (PLA, Surgiwrap™) in reducing adhesions after thyroid surgery. Materials and methods: A randomized-controlled experimental animal model was utilized. Forty-eight male Wistar Albino rats were randomly divided into 3 equal groups, forming study and control groups. Thyroid surgery was performed in all subjects. HA-CMC and PLA were applied between the thyroid zone and strap muscles after thyroid surgery …
Adverse Events Associated With Exchange Transfusion And Etiology Of Severe Hyperbilirubinemia In Near-Term And Term Newborns, Ali̇ Bülbül, Feri̇de Füsun Okan, Emel Kabakoğlu Ünsür, Asi̇ye Nuhoğlu
Adverse Events Associated With Exchange Transfusion And Etiology Of Severe Hyperbilirubinemia In Near-Term And Term Newborns, Ali̇ Bülbül, Feri̇de Füsun Okan, Emel Kabakoğlu Ünsür, Asi̇ye Nuhoğlu
Turkish Journal of Medical Sciences
To assess clinical features, etiology, and complications in term and near-term newborns who received exchange transfusion. Materials and methods: Infants with >=35 gestational weeks admitted to our neonatal intensive care unit in the first 30 days of life and underwent exchange transfusion due to severe hyperbilirubinemia between 2002 and 2008 were included. Clinical features, etiology of hyperbilirubinemia, and complications of exchange transfusion were assessed. Results: Exchange transfusion was performed 86 times in a total of 73 patients. Eleven patients received exchange transfusion twice, and 1 patient 3 times. A great proportion of the patients (61.6%) were male, and mean (± …
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Turkish Journal of Medical Sciences
Urginea maritima (Um) is a plant native to especially Turkey and the Mediterranean area. In this study, we investigated whether Um extract exerted cytotoxicity on cancer cells. Materials and methods: We made various extracts of Um. These extracts in varying concentrations were added to an A549 NSCLC cell culture, alone or with gemcitabine and/or cisplatin. Growth inhibition was tested by the MTT assay and an Annexin V-FITC apoptosis detection kit Results: The onion Um extract (1 µg/mL) was more cytotoxic than cisplatin (1 µg/mL), gemcitabine (1 nm/mL), and leaf Um extract (1 µg/mL) with P < 0.001, P = 0.097, and P < 0.001, respectively. The efficacy of Um extract was further improved by the addition of an antioxidant cocktail to an IC_{50} value of 0.02 µg/mL. Conclusion: Um extract has been shown for the first time to be a strong candidate for drug development in solid tumors. Our studies continue to further define the specific antitumor compound(s) in this extract.
Ex Vivo Produced Oral Mucosa Equivalent Preliminary Report: A Technical Note, Gürkan Raşi̇t Bayar
Ex Vivo Produced Oral Mucosa Equivalent Preliminary Report: A Technical Note, Gürkan Raşi̇t Bayar
Turkish Journal of Medical Sciences
The aim of this study was to produce of ex vivo oral mucosal equivalent. The continuous stratified layer of human oral keratinocytes was grown on a cadaveric human dermal matrix in a defined culture medium without a feeder layer. Materials and methods: Human oral keratinocytes from a keratinized oral mucosa biopsy specimen were enzymatically dissociated and cultured in a serum-free defined culture medium, "EpiLife" (Cascade Biologics, Portland, OR, USA), containing a low calcium concentration of 0.06 mM. Oral keratinocytes were expanded one passage. Once a sufficient population of keratinocytes was reached, they were seeded onto the type IV collagen coated …
Evaluation Of Gdx Parameters By Using Information Theory, Umut Arslan, Banu Bozkurt, Ahmet Ergun Karaağaoğlu, Murat Tanju İrkeç
Evaluation Of Gdx Parameters By Using Information Theory, Umut Arslan, Banu Bozkurt, Ahmet Ergun Karaağaoğlu, Murat Tanju İrkeç
Turkish Journal of Medical Sciences
To evaluate the performance of GDx parameters in the diagnosis of glaucoma by using information theory and compare the results obtained using receiver operating characteristic (ROC) curve analysis, which is a traditional method. Materials and methods: Retinal nerve fiber layer thickness was measured in 270 eyes with glaucoma and 81 normal eyes with scanning laser polarimeter (NFA GDx version, 1.0.08), and 14 GDx parameters were calculated. Both ROC curve analysis and information theory were used to determine the best GDx parameters. The best cut-off points of these parameters were obtained using information theory for glaucoma prevalence (Pr) of 1%, 2%, …
Which Predicts The Cardiovascular Risk Best In Elderly Metabolic Syndrome Patients: Atp Iii Or Idf?, Serpi̇l Aydin, Ayfer Gemalmaz, Tufan Nayi̇r, Şule Özkan
Which Predicts The Cardiovascular Risk Best In Elderly Metabolic Syndrome Patients: Atp Iii Or Idf?, Serpi̇l Aydin, Ayfer Gemalmaz, Tufan Nayi̇r, Şule Özkan
Turkish Journal of Medical Sciences
As metabolic syndrome (MetS) is one of the major determinants of cardiovascular disease, it is important to detect and intervene with MetS in order to minimize cardiovascular risk. The objectives of this study were to identify the prevalence of MetS in our elderly patients and to evaluate the ability IDF and ATP III to predict the cardiovascular risk. Materials and methods: This cross-sectional study included patients above 65 years attending the outpatient clinic of a hospital over a 4-year period and who gave oral informed consent for participation in the study. ATP III and IDF criteria were compared according to …
Invasive Device-Associated Nosocomial Infections Of A Teaching Hospital In Turkey; Four Years’ Experience, Aslihan Candevi̇r, Behi̇ce Kurtaran, Fi̇li̇z Ki̇bar, Emre Karakoç, Hasan Sali̇h Zeki̇ Aksu, Yeşi̇m Taşova
Invasive Device-Associated Nosocomial Infections Of A Teaching Hospital In Turkey; Four Years’ Experience, Aslihan Candevi̇r, Behi̇ce Kurtaran, Fi̇li̇z Ki̇bar, Emre Karakoç, Hasan Sali̇h Zeki̇ Aksu, Yeşi̇m Taşova
Turkish Journal of Medical Sciences
To determine our setting's IDAI rates, infecting microorganisms, and their resistance patterns to achieve standardization and make comparisons among other Turkish and developed country hospitals all over the world. Materials and methods: The numbers of total patient days, ventilator days, central catheter days and, urinary catheter days in the ICUs were recorded and IDAI rates were calculated. Clinical specimens were obtained from patients, cultivated at appropriate culture media, and infecting microorganisms and resistance patterns were determined. Results: Totally 1450 invasive device-associated infection episodes were determined (16.4% of patients) with a rate of 21.12/1000 days. Ventilator associated pneumonia rate was 22.05/1000 …
Evaluation Of Rubella, Toxoplasma Gondii, And Cytomegalovirus Seroprevalences Among Pregnant Women In Denizli Province, Aysun Karabulut, Yusuf Polat, Meral Türk, Yasemi̇n Işik Balci
Evaluation Of Rubella, Toxoplasma Gondii, And Cytomegalovirus Seroprevalences Among Pregnant Women In Denizli Province, Aysun Karabulut, Yusuf Polat, Meral Türk, Yasemi̇n Işik Balci
Turkish Journal of Medical Sciences
There is no national screening program for rubella, Toxoplasma gondii, and cytomegalovirus (CMV) infections for pregnant women in Turkey. The purpose of this study was to determine the prevalence of these infections among pregnant women in Denizli province, and to review seroprevalences reported from different regions of Turkey. Materials and methods: Between April 2008 and April 2009, 1268 women were investigated for rubella, 1102 for toxoplasma, and 1000 women for CMV seroprevalences in the first trimester of pregnancy. Toxoplasma and rubella IgM and IgG antibodies were assayed by the automated Vitros ECiQ system based on an immunometric technique. Cytomegalovirus IgM …
Relationship Between Pon1 Phenotype And Headache Duration In Migraine Patients, Şahbetti̇n Selek, Recep Alp, Selen İlhan Alp, Abdullah Taşkin
Relationship Between Pon1 Phenotype And Headache Duration In Migraine Patients, Şahbetti̇n Selek, Recep Alp, Selen İlhan Alp, Abdullah Taşkin
Turkish Journal of Medical Sciences
The available data on the activity of paraoxonase-1 (PON1) in patients suffering from migraine without aura (MWoA) is scarce. The present study was conducted to fulfill the objective of investigating the probability of an association between PON1 phenotype distribution and headache duration in patients suffering from MWoA. Materials and methods: Seventy-six patients who suffer from MWoA and were not experiencing attacks at the time and 65 healthy volunteers were enrolled for the purpose of evaluation in the present study. Results: The levels of serum paraoxonase, arylesterase activities, and lipid hydroperoxide (LOOH) were determined for these subjects. The results obtained revealed …
Serum Paraoxonase And Arylesterase Activities In Iron Deficiency Anemia During Pregnancy, Hakan Camuzcuoğlu, Harun Toy, Mehmet Vural, Aysun Camuzcuoğlu, Abdullah Taşkin, Haki̇m Çeli̇k
Serum Paraoxonase And Arylesterase Activities In Iron Deficiency Anemia During Pregnancy, Hakan Camuzcuoğlu, Harun Toy, Mehmet Vural, Aysun Camuzcuoğlu, Abdullah Taşkin, Haki̇m Çeli̇k
Turkish Journal of Medical Sciences
To investigate serum paraoxonase and arylesterase activities, and lipid hydroperoxide levels in pregnant women with iron deficiency anemia. Materials and methods: Paraoxonase and arylesterase activities, and lipid hydroperoxide levels were assessed for pregnant women with iron deficiency anemia (n = 50) and controls (n = 70). Serum basal and salt-stimulated paraoxonase, and arylesterase activities were measured spectrophotometrically. The lipid hydroperoxide levels were measured by ferrous ion oxidation xylenol orange assay. In addition, lipid parameters were determined by routine laboratory methods. Results: Basal and salt-stimulated paraoxonase, and arylesterase activities were significantly lower (P = 0.026, P = 0.031, and P = …
The Cytomorphological Analysis Of Buccal Mucosa Cells In Smokers, Mustafa Göregen, Hayati̇ Murat Akgül, Cemal Gündoğdu
The Cytomorphological Analysis Of Buccal Mucosa Cells In Smokers, Mustafa Göregen, Hayati̇ Murat Akgül, Cemal Gündoğdu
Turkish Journal of Medical Sciences
To examine the effect of smoking on normal buccal mucosa cytomorphologically. Materials and methods: Forty individuals aged between 40 and 60, comprising 23 smokers (14 male, 9 female) and 17 and non-smokers (10 male, 7 female), were included in the study. The buccal epithelial cells of these individuals were collected with a brush and the cells were measured cytomorphometrically using software. Results: The average nuclear area (NA), nuclear perimeter (NP), minimal nuclear diameter (D-min), and maximal nuclear diameter (D-max) were 46.00 ± 11.31, 28.18 ± 2.43, 6.18 ± 0.88, and 10.00 ± 0.94, respectively, in the control group, and 53.61 …
In Vitro Effect Of Resveratrol Against Oxidative Injury Of Human Coronary Artery Endothelial Cells, Oya Sayin, Nur Arslan, Zeki̇ye Sultan Altun, Gül Akdoğan
In Vitro Effect Of Resveratrol Against Oxidative Injury Of Human Coronary Artery Endothelial Cells, Oya Sayin, Nur Arslan, Zeki̇ye Sultan Altun, Gül Akdoğan
Turkish Journal of Medical Sciences
Reactive oxygen species induce oxidative stress that may contribute to endothelial dysfunction. In addition to endogen antioxidants, adding antioxidants to diet has been used to reduce oxidative-stress-induced endothelial dysfunction. Resveratrol is a natural phytoalexin which has many effects including antioxidant activity. The aim of this study was to investigate whether resveratrol could protect human coronary artery endothelial cells against in vitro oxidative-stress-mediated injury. Materials and methods: Human coronary artery endothelial cells were treated with varying concentrations of hydrogen peroxide for different durations and hydrogen peroxide plus varying concentrations of resveratrol. Then cell death was measured using lactate dehydrogenase release. Human …
The Role Of Red Cell Distribution Width As A Marker In Inflammatory Bowel Disease, Mehmet Arhan, İbrahi̇m Koral Önal, Adnan Taş, Mevlüt Kurt, İsmai̇l Hakki Kalkan, Yasemi̇n Özi̇n, Bi̇lge Tunç, Aysel Ülker
The Role Of Red Cell Distribution Width As A Marker In Inflammatory Bowel Disease, Mehmet Arhan, İbrahi̇m Koral Önal, Adnan Taş, Mevlüt Kurt, İsmai̇l Hakki Kalkan, Yasemi̇n Özi̇n, Bi̇lge Tunç, Aysel Ülker
Turkish Journal of Medical Sciences
To determine whether red cell distribution width could be used for the assessment of disease activity in patients with inflammatory bowel disease. Materials and methods: A total of 165 patients with inflammatory bowel disease (105 ulcerative colitis; 60 Crohn's disease) and 43 healthy blood donors were included in this retrospective study in a tertiary care setting. The medical records of the patients were reviewed to note clinical activity indices, red cell distribution width, serum C reactive protein, erythrocyte sedimentation rates, leukocyte, and platelet counts. Results: Red cell distribution width, serum C reactive protein, erythrocyte sedimentation rate, platelet count, and the …
Immunomodulatory Role Of Leptin Treatment In Experimental Sepsis Caused By Gram Negative Bacteria, Cemi̇le Koca, Havva Şahi̇n Kavakli, Özlem Alici
Immunomodulatory Role Of Leptin Treatment In Experimental Sepsis Caused By Gram Negative Bacteria, Cemi̇le Koca, Havva Şahi̇n Kavakli, Özlem Alici
Turkish Journal of Medical Sciences
To investigate the effect of leptin treatment on circulating inflammatory cytokines and on tissue damage in experimental rat model of gram-negative sepsis. Materials and methods: Adult male Wistar rats, 28 in total, were randomly divided into 4 groups (n = 7): sham, leptin, sepsis, and sepsis group treated with leptin (sepsis+leptin). Sepsis was induced by intraperitoneal (ip) injection of 2 × 10^{10} CFU of Escherichia coli ATCC 25922. Leptin and sepsis+leptin groups received a single dose ip 0.1 mg/kg leptin, while sham group received 1 mL of ip saline. Rats were sacrificed 24 h after the induction of sepsis. Blood …
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Turkish Journal of Medical Sciences
The purpose of this study was comparison of the glutamate dehydrogenase (gdh) and triose phosphate isomerase (tpi) genes for detection and genetic characterization of Giardia lamblia (G. lamblia) in human stool by polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism (RFLP). Our assay was specific and distinguished between G. lamblia assemblages A and B. Materials and methods: Among the 325 stool samples obtained from patients with acute gastroenteritis hospitalized in the Pediatric Hospital and infected humans referred to the Tabriz Reference Laboratory (TRL), 34 Giardia-positive stool samples were identified by conventional techniques. Two assays-PCR and PCR-RFLP-targeting the tpi and …
Prevalence Of Cutaneous Mycoses Among Workers, Ali Zarei Mahmoudabadi, Baharea Izadi
Prevalence Of Cutaneous Mycoses Among Workers, Ali Zarei Mahmoudabadi, Baharea Izadi
Turkish Journal of Medical Sciences
The aim of present study was to determine the prevalence of cutaneous mycoses in workers employed in different areas of the Ahvaz Jundishapur University of Medical Sciences. Materials and methods: In the present study 128 employees who held different positions (gardeners, lab cleaners, sanitary workers, repair workers, dishwashers, and cooks) at the Ahvaz Jundishapur University of Medical Sciences were studied. All workers were visited by a physician and 34 (26.6%) were suspected of having cutaneous fungal diseases. Several skin scraping and nail clipping samples were collected from the study participants. In addition, the Scotch Tape method was used for sampling …
A Determination Of The Factors That Affect The Level Of Pediatric Nurses' Liking Of Children, Yurdagül Erdem, Veli̇ Duyan
A Determination Of The Factors That Affect The Level Of Pediatric Nurses' Liking Of Children, Yurdagül Erdem, Veli̇ Duyan
Turkish Journal of Medical Sciences
Every person under the age of 18 is a child. One's attitude towards children is made up of the person's basic beliefs about children and their reaction to the idea of being with children. Pediatric nurses are expected to understand children's physical, intellectual, emotional, and social development, to advocate for children, and to show affection towards and interest in children. This study is conducted to determine the level of liking of children of nurses who are working at pediatric clinics. Materials and methods: This descriptive study was conducted on 207 nurses employed at pediatric clinics of university and state hospitals. …
Evaluation Of Health-Related Quality Of Life Of Women Living In A City Center In The East Of Turkey, Nüket Paksoy Erbaydar, Nazmi̇ Bi̇li̇r, Lütfi̇ye Hi̇lal Özcebe, Songül Vai̇zoğlu, Di̇lek Aslan
Evaluation Of Health-Related Quality Of Life Of Women Living In A City Center In The East Of Turkey, Nüket Paksoy Erbaydar, Nazmi̇ Bi̇li̇r, Lütfi̇ye Hi̇lal Özcebe, Songül Vai̇zoğlu, Di̇lek Aslan
Turkish Journal of Medical Sciences
To evaluate the health-related quality of life of women living in Van city center by SF-36 and its association with the women's characteristics. Materials and methods: The women (n = 1527) answered a questionnaire through a face-to-face interview, and some measurements were made. The variations of physical component score (PCS) and mental component score (MCS) of SF-36 were investigated by non-parametric tests, and by linear regression analysis. Results: The percentage of early marriages among married women was 55.6. Number of pregnancies per married woman was 4.5 ± 2.8, the lowest mean in vitality (44.0 ± 20.6) and the highest mean …
Distribution Of Coronary Artery Risk Factors: A Regional Analysis, Mehmet Bostan, Ömer Şatiroğlu, Hüseyi̇n Avni̇ Uydu, Yüksel Çi̇çek, Aytun Çanga, Zaki̇r Karadağ, Ahmet Temi̇z, Yavuz Uğurlu, Mehtap Atak, Engi̇n Bozkurt
Distribution Of Coronary Artery Risk Factors: A Regional Analysis, Mehmet Bostan, Ömer Şatiroğlu, Hüseyi̇n Avni̇ Uydu, Yüksel Çi̇çek, Aytun Çanga, Zaki̇r Karadağ, Ahmet Temi̇z, Yavuz Uğurlu, Mehtap Atak, Engi̇n Bozkurt
Turkish Journal of Medical Sciences
To analyze the frequency and distribution of coronary artery risk factors in the city of Rize and its surrounding areas. Materials and methods: This observational study included 452 patients (333 men, 119 women). In addition to demographic characteristics of the patients, conventional risk factors were also recorded. The patients were grouped according to their ages, gender, and electrocardiographic characteristics. Results: The mean age of participants was 63 ± 13 years and 74% were male. Smoking and hypertension (HT) were seen more often (71%) in younger male patients. No difference among age groups was detected with regard to the occurrence of …
Hepatitis B, Hepatitis C, Hiv, And Vdrl Seroprevalence Of Blood Donors In Mersin, Turkey, Seva Öner, Gülçi̇n Yapici, Caferi̇ Tayyar Şaşmaz, Ahmet Öner Kurt, Resul Buğdayci
Hepatitis B, Hepatitis C, Hiv, And Vdrl Seroprevalence Of Blood Donors In Mersin, Turkey, Seva Öner, Gülçi̇n Yapici, Caferi̇ Tayyar Şaşmaz, Ahmet Öner Kurt, Resul Buğdayci
Turkish Journal of Medical Sciences
The aim of this study was to determine the seroprevalence and affecting factors of Hepatitis B surface antigen (HbsAg), hepatitis C virus antibody (anti-HCV), anti human immunodeficiency virus (anti-HIV), and VDRL in blood donors in Mersin. Materials and methods: This was a retrospective, descriptive study. All blood centers in Mersin were included in the study. The medical records of 30,716 blood donors were evaluated. The data were analyzed using descriptive analysis, linear-by-linear association test, and the Pearson chi-square significance test. Results: Of the donors, 691 (2.2%) had positive HbsAg, 125 (0.4%) had positive anti-HCV, and 46 (0.1%) had positive VDRL …
Investigation Of Toxin Genes In Staphylococcus Aureus Strains Isolated In Mustafa Kemal University Hospital, Cemi̇l Demi̇r, Özkan Aslantaş, Ni̇zami̇ Duran, Sabahatti̇n Ocak, Burçi̇n Özer
Investigation Of Toxin Genes In Staphylococcus Aureus Strains Isolated In Mustafa Kemal University Hospital, Cemi̇l Demi̇r, Özkan Aslantaş, Ni̇zami̇ Duran, Sabahatti̇n Ocak, Burçi̇n Özer
Turkish Journal of Medical Sciences
The aim of this study was to investigate the presence of genes encoding staphylococcal enterotoxins (SEs), exfoliative toxins (ETAs, ETBs), and toxic shock syndrome toxin-1 (TSST-1) by polymerase chain reaction (PCR) in Staphylococcus aureus strains isolated from various clinical samples from the Mustafa Kemal University Hospital. In addition, PCR-based restriction fragment length polymorphism (RFLP) analysis of the coa gene was employed to genotype the isolates. Materials and methods: A total of 120 S. aureus strains isolated from various clinical samples (blood, wounds, urine, conjuctival swabs, and tracheal aspirate) over a 1 year period, 2007-2008, were used in this study. Results: …
Dimensions Of Water Contamination In The Subprovinces Of Adana Province, Turkey, Ferdi̇ Tanir, Beri̇l Akçi̇men, Fati̇h Köksal, Necdet Aytaç, İbrahi̇m Cengi̇zler
Dimensions Of Water Contamination In The Subprovinces Of Adana Province, Turkey, Ferdi̇ Tanir, Beri̇l Akçi̇men, Fati̇h Köksal, Necdet Aytaç, İbrahi̇m Cengi̇zler
Turkish Journal of Medical Sciences
To determine the dimension of the contamination of the drinking and utility water in the touristic Bahçe district of the Karataş subprovince of Adana province, and to share our views on how to raise the quality of the water in the district. Materials and methods: In 2007 and 2008, 80 samples were taken 8 times, on a seasonal basis, from the drinking water and sea water of the Bahçe district. Eleven organic and inorganic parameters were measured and presented following a comparison with criteria values Results: Ni, Zn, Cu, Pb, NO3-N, COD, and phenol contamination parameters were found to be …
The Causes Of Deaths In An Industry-Dense Area: Example Of Dilovası (Kocaeli)*, Onur Hamzaoğlu, Ni̇lay Eti̇ler, Cavi̇t Işik Yavuz, Çi̇ğdem Çağlayan
The Causes Of Deaths In An Industry-Dense Area: Example Of Dilovası (Kocaeli)*, Onur Hamzaoğlu, Ni̇lay Eti̇ler, Cavi̇t Işik Yavuz, Çi̇ğdem Çağlayan
Turkish Journal of Medical Sciences
Chemical pollutants caused by the industry have changed both mortality rates and morbidity patterns causing new illnesses over the last few decades. This study aimed to determine the causes and characteristics of deaths related to cancer in 2004 in Dilovası, Kocaeli, which was mainly used as a production, storage, and transfer area for a variety of industries, such as chemical, metal and metal products, energy, and machinery. Materials and methods: In this cross-sectional study, death records of 8 different registry/record screenings belonging to 4 public institutions in Dilovası in 2004 were investigated. The study population included deaths in 2004 and …
Serum Osteoprotegerin (Opg) Measurement In Behçet's Disease, Nafi̇ye Fulya İlhan, Nesri̇n Demi̇r, Tamer Demi̇r, Ahmet Gödekmerdan
Serum Osteoprotegerin (Opg) Measurement In Behçet's Disease, Nafi̇ye Fulya İlhan, Nesri̇n Demi̇r, Tamer Demi̇r, Ahmet Gödekmerdan
Turkish Journal of Medical Sciences
Recent studies indicate that osteoprotegerin (OPG) acts as an important molecule in the development of vascular diseases. The aim of the present study was to examine the association between serum OPG levels and Behcet's disease (BD). Materials and methods: Twenty-five patients with BD and 20 healthy control subjects, matched for age and sex, were included in this study. Serum levels of OPG were determined using ELISA. Results: We found that serum levels of OPG were significantly higher in patients with BD than in healthy control subjects (813.75 ± 11 vs. 655.56 ± 17 pg/mL, P = 0.002). There was no …
Effects Of Different Propofol Injection Speeds On Blood Pressure, Dose, And Time Of Induction, Şennur Uzun, Burcu Akbay Özkaya, Ömer Savaş Yilbaş, Banu Ayhan, Altan Şahi̇n, Ülkü Aypar
Effects Of Different Propofol Injection Speeds On Blood Pressure, Dose, And Time Of Induction, Şennur Uzun, Burcu Akbay Özkaya, Ömer Savaş Yilbaş, Banu Ayhan, Altan Şahi̇n, Ülkü Aypar
Turkish Journal of Medical Sciences
Blood concentration of propofol depends on many factors, such as age, gender, body weight, dose, infusion rate, and cardiac output. This study primarily investigated the effect of infusion rate on blood pressure changes. Secondarily induction time and induction dose were studied. Materials and methods: Propofol was administered at 200 (P200), 300 (P300), or 400 mL h-1 (P400) until loss of consciousness using bispectral index (BIS) monitoring in 72 adult patients. Change in blood pressure, induction time, and dose of propofol were compared among 3 groups. Results: The decreases in systolic and mean arterial pressure were statistically significant in the P200 …
The Effects Of Taping And Foot Exercises On Patients With Hallux Valgus: A Preliminary Study, Banu Bayar, Suat Erel, İbrahi̇m Engi̇n Şi̇mşek, Erkan Sümer, Kiliçhan Bayar
The Effects Of Taping And Foot Exercises On Patients With Hallux Valgus: A Preliminary Study, Banu Bayar, Suat Erel, İbrahi̇m Engi̇n Şi̇mşek, Erkan Sümer, Kiliçhan Bayar
Turkish Journal of Medical Sciences
To determine the effects of taping and foot exercises on patients with hallux valgus. Materials and methods: The study included 20 female patients. The subjects were divided into 2 groups, the study and control groups. The study group was treated with taping and foot exercises, and the control group was treated only with foot exercises. A goniometer was used to determine the angle of hallux valgus. Foot pain intensity was assessed by the visual analog scale (VAS), and walking ability was evaluated using the walking ability scale (WAS). Results: At the end of the 8-week treatment period, a significant decrease …
The Effects Of Sequential Treatment As A First-Line Therapy For Helicobacter Pylori Eradication, Mehmet Demi̇r, Hi̇lmi̇ Ataseven
The Effects Of Sequential Treatment As A First-Line Therapy For Helicobacter Pylori Eradication, Mehmet Demi̇r, Hi̇lmi̇ Ataseven
Turkish Journal of Medical Sciences
There is no effective eradication regimen for Helicobacter pylori (HP) in Turkey. Recent studies have shown that sequential therapy may be superior to the standard triple therapy in terms of the eradication of HP. In this study, we aim to assess the efficacy of a 14-day sequential treatment regimen as a first-line therapy for HP eradication. Materials and methods: This is a prospective, open-label, single-centre study. The study involved 86 consecutive patients with nonulcer dyspepsia. All patients were randomly assigned into 2 study groups at a 2:1 ratio using random sampling numbers. The first group of patients were administered a …
The Protective Effect Of Dexamethasone And Lactate Against Cisplatin-Induced Ototoxicity, Ari̇f Şanli, Sedat Aydin, Zeynep Alev Sarisoy, Mustafa Paksoy, Emi̇n Ayduran, Özlem Çelebi̇ Erdi̇vanli
The Protective Effect Of Dexamethasone And Lactate Against Cisplatin-Induced Ototoxicity, Ari̇f Şanli, Sedat Aydin, Zeynep Alev Sarisoy, Mustafa Paksoy, Emi̇n Ayduran, Özlem Çelebi̇ Erdi̇vanli
Turkish Journal of Medical Sciences
To compare the protective effect of dexamethasone and lactate against cisplatin-induced ototoxicity. Materials and methods: Thirty Wistar rats were randomly divided into 4 groups. After the rats were sedated with intraperitoneal (IP) ketamine hydrochloride (50 mg/kg) and xylazine (7.5 mg/kg), baseline ABRs (auditory brainstem evoked responses) were measured in response to clicks and tone pips of 4, 8, 12, and 16 kHz. After auditory thresholds were determined, the animals received drug administration as follows: Group 1 (n: 6) received intratympanic (IT) saline (0.9% NaCl) solution, Group 2 (n: 8) IP cisplatin (20 mg/kg) alone, Group 3 (n: 8) IT dexamethasone …
A Comparison Of The Diagnostic Value Of 19-Gauge Histology And 22-Gauge Cytology Needles In Bronchoscopy For The Evaluation Of Endobronchial Lesions, Eli̇f Yilmazel Uçar, Mehmet Meral, Meti̇n Akgün, Sare Şi̇pal, Hasan Kaynar, Leyla Sağlam, Ali̇ Meti̇n Görgüner
A Comparison Of The Diagnostic Value Of 19-Gauge Histology And 22-Gauge Cytology Needles In Bronchoscopy For The Evaluation Of Endobronchial Lesions, Eli̇f Yilmazel Uçar, Mehmet Meral, Meti̇n Akgün, Sare Şi̇pal, Hasan Kaynar, Leyla Sağlam, Ali̇ Meti̇n Görgüner
Turkish Journal of Medical Sciences
To prospectively compare the sensitivity of Wang 22-gauge needle aspiration and 19-gauge needle aspiration with bronchial biopsy and determine whether there was difference between 22-gauge and 19-gauge needle aspirations in the diagnosis of endobronchial malignancies. Materials and methods: All patients (63 patients) in the study underwent fiberoptic bronchoscopy that included 22-gauge needle aspiration and 19-gauge needle aspiration. In 50 patients bronchial biopsy was done. The sensitivities of the individual techniques were compared. Results: Cancer was diagnosed in 48 patients by 22-gauge needle aspiration and 19-gauge needle aspiration, and in 43 patients by bronchial biopsy. The sensitivity of bronchial biopsy was …