Medicine and Health Sciences Commons^™

Epilepsy In Pakistan, Hasan Aziz

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Genes And Epilepsies, Khurram A Siddiqui, Iram Siddiqui, Rehan Ali, Hani Benamer

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Neuroradiology, Zafar Sajjad

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Serotonin Syndrome, Naila Bhutto, Muhammad Naim Siddiqi

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Coexistence Of Neurotransmitters Inparkinson's Disease, G. Ali Qureshi, Aftab A. Qureshi, Shuja Ali Syed, S.H. Parvez

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Diarrea Viral Bovina Y Animales Portadores Del Virus En Hatos Productores De Leche De La Irrigación De Majes, Arequipa, John C. Huaman G., Hermelinda G. Rivera, Mariluz Araínga, Cesar Gavidia Ch., Alberto Manchego S.

Journal Articles: Pharmacology & Experimental Neuroscience

The objective of this study was to determine the prevalence of bovine viral diarrhea virus (BVDV) and persistently infected (PI) animals in dairy herds located in Majes, Arequipa, Peru. In the first phase, 204 bulk tank milk samples from herds were collected and sent to the local commercial processing plant in Majes for detection of antibodies against BVDV by indirect ELISA test. In the second phase, 286 blood samples from 57 were collected strong positive (Optical Density [OD] ≥ 0.900) for the detection of herds antibodies against BVDV and in PI animals by the indirect and capture ELISAs respectively. In …

Download Full Pdf Issue Of Thomas Jefferson University Mph Public Health Link Newsletter, Vol. 3, Iss. 6, July 2007

Public Health Link

This issue includes an article written by Dr. James Plumb on "Public Health Perspective: Linking Public Health and Medical Education at Jefferson" along with thesis presenters and other program announcements.

Autocrine Prolactin Promotes Prostate Cancer Cell Growth Via Janus Kinase-2-Signal Transducer And Activator Of Transcription-5a/B Signaling Pathway., Ayush Dagvadorj, Sean Collins, Jean-Baptiste Jomain, Junaid Abdulghani, James Karras, Tobias Zellweger, Hongzhen Li, Martti Nurmi, Kalle Alanen, Tuomas Mirtti, Tapio Visakorpi, Lukas Bubendorf, Vincent Goffin, Marja T Nevalainen

Department of Cancer Biology Faculty Papers

The molecular mechanisms that promote progression of localized prostate cancer to hormone-refractory and disseminated disease are poorly understood. Prolactin (Prl) is a local growth factor produced in high-grade prostate cancer, and exogenously added Prl in tissue or explant cultures of normal and malignant prostate is a strong mitogen and survival factor for prostate epithelium. The key signaling proteins that mediate the biological effects of Prl in prostate cancer are Signal Transducer and Activator of Transcription (Stat)-5a/5b via activation of Janus kinase-2. Importantly, inhibition of Stat5a/b in prostate cancer cells induces apoptotic death. Using a specific Prl receptor antagonist (Delta1-9G129R-hPRL), we …

Craniocerebral Aspergillosis In Immunocompetent Hosts: Surgical Perspective, Muhammad Shahzad Shamim, Arshad A. Siddiqui, Ather Enam, Ahmed Ali Shah, Rashid Jooma, Saleha Anwar

Section of Neurosurgery

Craniocerebral aspergillosis is a rare but dangerous variety of central nervous system infections. Surgery is being widely recognized as the cornerstone of management. Due to the rarity of the disease, difficulty and delay in diagnosis and poor outcome, there is very little in the literature regarding the various surgical strategies that may be adopted in these patients. Early aggressive surgery followed by chemotherapy offers the best chances. Surgical planning would depend upon the type and location of the disease process as well as the condition of the patient. Perioperative care holds immense importance and knowledge of possible complications is essential. …

Role Of Surgery In The Management Of Low Grade Glioma, Faraz Kazim, Ather Enam

Section of Neurosurgery

No abstract provided.

Jefferson Alumni Bulletin – Volume 56, Number 3, Summer 2007

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 56, Number 3, Summer 2007

Dean’s Column: Estrangement; Page 2

Findings: Targeting Adrenal Gland Could Be Key Strategy Against Heart Failure, Rabies-based Vaccine Could Be Effective Against HIV; Page 6

On Campus; Page 8

Tackling the Tough Questions; Page 11

How Microscopic is Microscopic Anatomy? Page 20

Class Notes; Page 22

In Memoriam; Page 24

Match Day; Page 26

By The Numbers; Match Day; Page 29

Weekend And Weekday Patterns Of Physical Activity In Overweight And Normal-Weight Adolescent Girls, Margarita S. Treuth, Diane J. Catellier, Kathryn H. Schmitz, Russell R. Pate, John P. Elder, Robert G. Mcmurray, Robert M. Blew, Song Yang, Larry S. Webber

Faculty Publications

Objective - To describe the patterns (specifically comparing weekdays and weekends classified by intensities) of physical activity (PA) measured by accelerometry in adolescent girls.

Research Methods and Procedures - Healthy sixth grade girls (n=1603), 11 to 12 years old, were randomly recruited from 36 schools participating in the Trial of Activity in Adolescent Girls. Age, ethnicity, socioeconomic status, weight, and height were taken. PA patterns were measured for 6 days using accelerometry.

Results - Adolescent girls spend most of their time in sedentary (52% to 57% of the day) and light activity (40% to 45% of the day) …

Perceived Individual, Social, And Environmental Factors For Physical Activity And Walking, Michelle L. Granner, Patricia A. Sharpe, Brent E. Hutto, Sarah Wilcox, Cheryl L. Addy

Faculty Publications

Background: Few studies have explored associations of individual, social, and environmental factors with physical and walking behavior. Methods: A random-digit-dial questionnaire, which included selected individual, social, and environmental variables, was administered to 2025 adults, age 18 y and older, in two adjacent counties in a southeastern state. Logistic regressions were conducted adjusting for age, race, sex, education, and employment. Results: In multivariate models, somewhat different variables were associated with physical activity versus regular walking. Self-efficacy (OR = 19.19), having an exercise partner (OR = 1.47), recreation facilities (OR = 1.54), and safety of trails from crime (OR = 0.72) were …

Retinol Binding Protein 4 Expression In Humans: Relationship To Insulin Resistance, Inflammation, And Response To Pioglitazone, Aiwei Yao-Borengasser, Vijayalakshmi Varma, Angela M. Bodles, Neda Rasouli, Bounleut Phanavanh, Mi-Jeong Lee, Tasha Starks, Leslie M. Kern, Horace J. Spencer Iii, Amir Adel Rashidi, Robert E. Mcgehee Jr., Susan K. Fried, Philip A. Kern

Clinical and Translational Science Faculty Publications

Context: Retinol binding protein 4 (RBP4) was recently found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance.

Objective: The aim was to determine the relationship between RBP4 and obesity, insulin resistance, and other markers of insulin resistance in humans.

Design and Patients: RBP4 mRNA levels in adipose tissue and muscle of nondiabetic human subjects with either normal or impaired glucose tolerance (IGT) were studied, along with plasma RBP4. RBP4 gene expression was also measured in adipose tissue fractions, and from visceral and sc adipose tissue (SAT) from surgical patients.

Setting: The study was …

Resected Serous Cystic Neoplasms Of The Pancreas: Locally Aggressive Behavior As A Predictor Of Malignant Disease? A Review Of 158 Patients With Recommendations For Treatment., Charles Galanis, Amir Zamani, John L. Cameron, Kurtis A. Campbell, Keith D. Lillemoe, David Caparrelli, David Chang, Ralph H. Hruban, Charles Yeo

Department of Surgery Faculty Papers

Background: Serous cystic neoplasms of the pancreas are regarded as a benign entity with rare malignant potential. Surgical resection is generally considered curative. Objective: To perform the largest single institution review of patients who underwent surgical resection for serous cystic neoplasms of the pancreas in the hopes of guiding future management. Methods: Between June 1988 and January 2005, 158 patients with serous cystic neoplasms of the pancreas underwent surgical resection. A retrospective analysis was performed. Univariate and multivariate models were used to determine factors influencing perioperative morbidity and mortality. Major complications were defined as pancreatic fistula or anastomotic leak, postoperative …

Collaboration Addresses Information And Education Needs Of An Urban Public Health Workforce, Deborah H. Charbonneau, Ellen B. Marks, Annette M. Healy, Carrie F. Croatt-Moore

Library Scholarly Publications

Addressing the health information needs of diverse, multiethnic, and multilingual communities can be both a challenge and an opportunity for libraries. The Vera P. Shiffman Medical Library at Wayne State University in Detroit, Michigan, is the only academic medical library in the Detroit area open to the public. The library provides services to many communities in southeastern Michigan. The diverse geographic area served by the library includes the nation’s highest concentration of Arab Americans. A review of the literature reveals that limited research has addressed how libraries can meet the health information needs of this target community. An understanding of …

Examining The Ability Of The Halstead -Reitan Battery And The Wide Range Achievement Test To Utilize Severity In Discriminating Among Alzheimer's Dementia Patients, Gina Gibson-Beverly

Doctoral Dissertations

Measuring change in cognitive status is essential for the diagnosis, prognosis, and treatment of brain dysfunction. Psychological abilities are differentially affected by brain dysfunction severity, as some abilities are more vulnerable to brain dysfunction than others. Neuropsychological assessments can be viewed as a continuum of "hold" and "don't hold" tests. "Hold" tests assess abilities that remain stable in spite of brain dysfunction, while "don't hold" tests measure skills that are significantly compromised by brain impairment. The present study ranks the Halstead-Reitan Battery (HRB) and the Wide Range Achievement Test (WRAT) subtests based on their ability to discriminate between two levels …

Evaluation Of A Sleep Hygiene Program To Improve Inmate Sleep Quality, Jennifer F. Hodges-Crowder

Doctoral Dissertations

Research investigating the effectiveness of treatments for inmates with poor sleep quality appears minimal. Some difficulties related to poor sleep quality can be addressed effectively with little time and expense. Studies show that psychoeducational interventions are effective in reducing sleep complaints and improving sleep quality in a variety of populations including college students and adults. However, the effect of sleep hygiene interventions on inmate sleep complaints is unknown. Thus, the purpose of this study was to evaluate a psychoeducational intervention program aimed at improving prison inmate sleep habits, length, and quality.

Participants of this study were inmates at a department …

Nonlinear Dynamical Analysis Of Brain Electrical Activity Due To Exposure To Weak Environmentally Relevant Electromagnetic Fields, Erik Alfonso Nilsen

Doctoral Dissertations

The reports dealing with the effects of weak electromagnetic fields (EMFs) on brain electrical activity have been inconsistent. We suspected that the use of linear models and their associated methods accounted for some of the variability, and we explored the issue by using a novel approach to study the effects of EMFs on the electroencephalogram (EEG) from rabbits and humans. The EEG was embedded in phase space and local recurrence plots were calculated and quantified to permit comparisons between exposed and control epochs from individual subjects. Statistically significant alterations in brain activity were observed in each subject when exposed to …

Keeping Insects At Bay: Beyond Deet, Thomas P. Rooney

Biological Sciences Faculty Publications

No abstract provided.

Comparison Of C. Elegans And C. Briggsae Genome Sequences Reveals Extensive Conservation Of Chromosome Organization And Synteny, Ladeana W. Hiller, Raymond D. Miller, Scott Everet Baird, Asif Chinwalla, Lucinda A. Fulton, Daniel C. Koboldt, Robert H. Waterston

Biological Sciences Faculty Publications

To determine whether the distinctive features of Caenorhabditis elegans chromosomal organization are shared with the C. briggsae genome, we constructed a single nucleotide polymorphism-based genetic map to order and orient the whole genome shotgun assembly along the six C. briggsae chromosomes. Although these species are of the same genus, their most recent common ancestor existed 80-110 million years ago, and thus they are more evolutionarily distant than, for example, human and mouse. We found that, like C. elegans chromosomes, C. briggsae chromosomes exhibit high levels of recombination on the arms along with higher repeat density, a higher fraction of intronic …

The Kentucky Plan Revisited: Lessons Learned From An Innovative Doctoral Education Program., Joel M. Lee, F. Douglas Scutchfield, Raymond Hill

Preventive Medicine and Environmental Health Faculty Publications

In the first doctoral education special issue of the Journal of Health Administration Education, the authors presented the University of Kentucky College of Public Health's plans for an innovative new Doctor of Public Health (Dr. P.H.) degree. The degree as designed, prepares graduates for professional practice, and included extensive supervised field experience as part of the academic training linking theory with practice. Based upon the interest that the Kentucky Dr.P.H. degree program received, the authors will share the experience of the degree's initial years of operation through a "lessons learned" paper. As the program evolved there have been many lessons …

The Importance Of Gender And Readiness To Change In The Prediction Of Drinking And Negative Consequences Of First-Year Student Drinkers, Margot E. Ackermann

Psychology Theses & Dissertations

College drinking is widespread, and binge drinkers can experience serious consequences. The present study examined the effectiveness of two interventions, expressive writing and behavioral monitoring, as well a combined condition, in reducing drinking and negative consequences associated with drinking. Gender differences and differences in readiness to change binge drinking were also assessed. Participants (N = 97) completed a pretest, eight weekly intervention activities, and a posttest during their first semester of college. An ANOVA tested the hypothesis that individuals higher in readiness to change binge drinking participated in more of the weekly intervention activities; this hypothesis was not supported. A …

The Depiction Of Alcohol Tobacco And Other Substances In Children's G & Pg-Rated Animated Films Post 2000, Lindsay F. Graham

Sociology & Criminal Justice Theses & Dissertations

This study will analyze the depiction of alcohol, tobacco, and other substances in G and PG-rated animated films from November 1, 2000 to December 31, 2005. These films will include those released in theaters and video in English, at least 60 minutes in length, and of the animated genre during this five-year window. There is evidence that due to recent societal pressures facing the Motion Picture Association of America and their rating guidelines, the presence of alcohol and tobacco in children's animated Grated films has lessened. These incidents of exposure have since moved up the rating totem pole to receive …

The Effect Of Intensity Of Aerobic Vo2max Resting Heart Rate And Blood Pressure, Shannan Elizabeth Gormley

Human Movement Studies & Special Education Theses & Dissertations

The AGSM recommends 20 to 60 minutes of continuous or intermittent activity 3 to 5 times per week to maintain cardio respiratory fitness (Pollock et al., 1998). The 1996 Surgeon General's Report on Physical Activity and Health indicates that Americans are not meeting these physical activity recommendations (DHHS). Several clear consequences of physical inactivity are the appearance of cardiovascular disease risk factors, such as hypertension, hyperlipidemia and obesity. Two recent review articles suggested that higher intensity exercise will elicit a greater reduction in cardiovascular disease risk factors (Swain and Franklin, 2002; Swain and Franklin, 2006). In order to determine whether …

Evidence For Disease Mediated Extinction: Correlation Between An Introduced Pathogen And Extinction Of Rattus Macleari On Christmas Island, Kelly B. Wyatt

Biological Sciences Theses & Dissertations

The Durham Collection and the Cambridge and Oxford University Museums provided the materials to investigate the possibility that the extinction of indigenous rats of Christmas Island was a result of disease introduced by infected ship rats (R. rattus) in 1899. The collections of H.E. Durham in 1901-1902 reveal that R. macleari was present on Christmas Island up to then and includes specimens of R. rattus together with specimens that exhibit characteristics of both R. rattus and R. macleari. Durham's notes indicate both R. rattus and R. macleari specimens were heavily infected with trypanosomes at the time of collection. In …

Migraine And Risk Of Stroke In Young Women, Theresa A. Nacey

Internet Journal of Allied Health Sciences and Practice

Purpose: To explore the relationship between migraine and incidence of stroke in young women by analyzing variables of oral contraceptive use, hypercoagulability, cardiac abnormalities, and silent brain infarcts. Method:Variables were reviewed through computerized databases and current literature examining evidence-based medicine studies specific to analyzing the incidence of strokes in women with migraines. Results: Six recent studies, four case control and two cohort studies, were identified. Research outcomes indicate that the risk of stroke is greater in women less than 35 years of age who had migraine with aura and who used oral contraceptives. Other pathophysiologic variables, which may link migraine …

Physical Therapy Students' Perspectives On Disability, Renee M. Williams

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this qualitative study was to examine physical therapy students’ learning about disability through an Exploring Perspectives on Disability (EPOD) learning event that was developed by School of Rehabilitative Science, McMaster University. EPOD consists of two scheduled classes discussing disability, a shadowing experience with an individual with a disability living in the community, and writing a reflective summary assignment about their learning. The EPOD was developed to broaden students’ perspectives regarding disability, promote a positive attitude about disability, and facilitate best practice approaches in community-based care. Method: Fifty-seven students in the first semester of a Master’s entry …

For Falls Sake: Older Carers' Perceptions Of Falls And Falls Risk Factors, Shylie Mackintosh, Caroline Fryer, Michele Sutherland

Internet Journal of Allied Health Sciences and Practice

Purpose: Older carers play an important role in falls prevention through their influence over their dependent’s actions and by their own behaviour. This study aimed to determine the perceptions of falls and fall-related risk factors by older carers in an Australian metropolitan community to inform the development of effective falls prevention strategies in this population. Method: A questionnaire was mailed to all members of a carers group in January 2003 and responses from carers aged 60 years or above were included in the study (n=121). Results: The majority of older carers (85%) understood that falls are a problem for their …

'It's All Part Of The Package' In Rural Allied Health Work: A Pilot Study Of Rewards And Barriers In Rural Pharmacy And Social Work, Julaine Allan, Judith Crockett, Patrick Ball, Margaret Alston, Kerri Whittenbury

Internet Journal of Allied Health Sciences and Practice

Objective: The objective of this pilot study was to identify personal and professional factors that influence health workers’ commitment to remaining in rural and remote areas with the aim of identifying research directions for a larger study and informing workforce recruitment and retention strategies. Design: Accidental sampling then qualitative interviews with pharmacists and social workers. Setting: Six rural communities with populations less than 5,000 in New South Wales, Australia. Methodology: Deductive and inductive analysis of data. Results: Common rewards included the value attached to pharmacists’ and social workers’ contributions to rural communities, ability to assist people to solve problems, and …