Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Public Health (564)
- Medical Specialties (517)
- Social and Behavioral Sciences (391)
- Medical Sciences (350)
- Life Sciences (290)
-
- Psychiatry and Psychology (248)
- Veterinary Medicine (185)
- Sociology (173)
- Dentistry (169)
- Rehabilitation and Therapy (157)
- Nursing (140)
- Arts and Humanities (139)
- Education (137)
- Other Psychiatry and Psychology (137)
- Physical Sciences and Mathematics (118)
- International Public Health (116)
- Demography, Population, and Ecology (107)
- Diseases (102)
- Family, Life Course, and Society (101)
- Animal Sciences (97)
- Mental and Social Health (97)
- History (88)
- Psychology (88)
- Medicine and Health (86)
- Surgery (80)
- Public Affairs, Public Policy and Public Administration (72)
- Business (71)
- Medical Education (71)
- Law (70)
- Institution
-
- Thomas Jefferson University (237)
- Aga Khan University (188)
- Wright State University (165)
- TÜBİTAK (147)
- Washington University School of Medicine (145)
-
- University of Nebraska - Lincoln (126)
- Chulalongkorn University (118)
- Population Council (112)
- The Texas Medical Center Library (76)
- University of Alabama at Birmingham (76)
- Virginia Commonwealth University (75)
- University of North Dakota (63)
- Loma Linda University (62)
- Nova Southeastern University (62)
- Old Dominion University (61)
- University of Kentucky (57)
- Marquette University (48)
- Western Kentucky University (48)
- American Dental Association (43)
- Western University (39)
- Dartmouth College (37)
- Marshall University (35)
- University of South Carolina (33)
- Taiwan Academy of Physical Medicine and Rehabilitation (32)
- Universitas Indonesia (32)
- University of Northern Iowa (30)
- Edith Cowan University (29)
- LSU Health New Orleans (29)
- University of Tennessee Health Science Center (29)
- Louisiana State University (24)
- Keyword
-
- Humans (159)
- English (96)
- Animals (76)
- Female (67)
- Male (62)
-
- Adult (45)
- Newsletter (44)
- Doctor of Philosophy (PhD) Heersink School of Medicine (40)
- Thomas Jefferson University (38)
- Mice (36)
- Reproductive Health (35)
- Metabolism (34)
- Genetics (30)
- Oral health (29)
- Newspaper (28)
- Poverty Gender and Youth (27)
- Broadsheet (26)
- Hurricane Katrina (26)
- Paper (26)
- Professional association (26)
- Public health (26)
- Models (25)
- Bacterial (22)
- Child (21)
- India (21)
- Genetic (20)
- HIV and AIDS (20)
- Youth (20)
- Adolescent (19)
- Mutation (19)
- Publication
-
- International Symposium on Aviation Psychology - 2007 (134)
- Open Access Publications (81)
- All ETDs from UAB (75)
- Turkish Journal of Veterinary & Animal Sciences (74)
- Turkish Journal of Medical Sciences (73)
-
- Theses and Dissertations (68)
- Faculty, Staff and Student Publications (67)
- Chulalongkorn Medical Journal (49)
- Reproductive Health (49)
- Faculty Publications (47)
- Department of Psychology: Faculty Publications (45)
- Loma Linda University Electronic Theses, Dissertations & Projects (45)
- The Thai Journal of Veterinary Medicine (42)
- Pakistan Journal of Neurological Sciences (PJNS) (39)
- Dartmouth Scholarship (37)
- Jefferson Surgical Solutions (37)
- Poverty, Gender, and Youth (34)
- Internet Journal of Allied Health Sciences and Practice (33)
- Physical Therapy Scholarly Projects (32)
- Rehabilitation Practice and Science (32)
- Occupational Therapy Capstones (30)
- HIV and AIDS (29)
- Posters (29)
- Kesmas (28)
- Theses and Dissertations (ETD) (28)
- Chulalongkorn University Dental Journal (27)
- ADA News (26)
- Electronic Theses and Dissertations (26)
- Dissertations (24)
- Population Health Matters (Formerly Health Policy Newsletter) (24)
- Publication Type
- File Type
Articles 421 - 450 of 3121
Full-Text Articles in Medicine and Health Sciences
Human Genetics Studies: The Case For Group Rights, Laura S. Underkuffler
Human Genetics Studies: The Case For Group Rights, Laura S. Underkuffler
Cornell Law Faculty Publications
No abstract provided.
Debate: A Teaching-Learning Strategy For Developing Competence In Communication And Critical Thinking, Michele Darby
Debate: A Teaching-Learning Strategy For Developing Competence In Communication And Critical Thinking, Michele Darby
Dental Hygiene Faculty Publications
The article highlights key benefits from debate as a teaching-learning strategy for developing critical thinking and analytical skills while fostering teamwork and communication. According to the author, it is an effective pedagogical strategy because of the level of responsibility for learning and active involvement required by all student debaters. She also notes that the debate strategy can be used as a method to achieve competencies in baccalaureate and graduate dental hygiene programs.
In Vitro Evaluation Of The Reciprocating Disposable Prophylaxis Angle Versus The Rotating Disposable Prophylaxis Angle In Extrinsic Stain Removal Effectiveness, Inma Lacross, Michele Darby, Sharon S. Stull, Carlene M. Lynch
In Vitro Evaluation Of The Reciprocating Disposable Prophylaxis Angle Versus The Rotating Disposable Prophylaxis Angle In Extrinsic Stain Removal Effectiveness, Inma Lacross, Michele Darby, Sharon S. Stull, Carlene M. Lynch
Dental Hygiene Faculty Publications
This study determined the extrinsic tooth stain removing effectiveness of a 90° counter-rotational disposable prophylaxis angle (DPA) with rubber cup compared to the traditional 360° unirotational DPA with rubber cup. Four randomly-assigned groups of cleaned, sterilized, extracted human teeth, artificially stained with coffee, tea, tobacco, and red wine, were polished on the buccal and lingual surfaces using one of the 2 DPAs. Each dependent variable (4 different stain types) was tested 4 times with each prophylaxis angle, using 4 prophylaxis paste conditions, and 3 different rpm; therefore, 2 trials x 2 angles x 3 speeds x 4 stains x 4 …
Bactericidal Effects Of Cold Plasma Technology On Geobacillus Stearothermophilus And Bacillus Cereus Microorganisms, Angela D. Morris, Gayle B. Mccombs, Susan L. Tolle, Mounir Laroussi, Wayne L. Hynes
Bactericidal Effects Of Cold Plasma Technology On Geobacillus Stearothermophilus And Bacillus Cereus Microorganisms, Angela D. Morris, Gayle B. Mccombs, Susan L. Tolle, Mounir Laroussi, Wayne L. Hynes
Dental Hygiene Faculty Publications
Cold plasma is a state of matter that contains a large number of particles that are electrically charged. Plasmas generate chemically reactive species and ultraviolet radiation making them useful in decontamination applications (Kong & Laroussi, 2003). Research regarding the inactivation of gram-positive bacteria by cold plasma has been studied by Laroussi et al (2003); however, there is limited research regarding the germicidal effectiveness of cold plasma on Geobacillus stearothermophilus and Bacillus cereus microorganisms. The purpose of this study was to determine if cold plasma technology inactivates Geobacillus stearothermophilus and Bacillus cereus vegetative cells and spores. This study consisted of 981 …
The Effectiveness Of Prophylactic Eye Drops On The Reversal Of Uv-Light Induced Cataracts, Contessa Bly Bowman
The Effectiveness Of Prophylactic Eye Drops On The Reversal Of Uv-Light Induced Cataracts, Contessa Bly Bowman
Theses and Dissertations
Cataracts are a cloudiness of the lens within the eye which obstructs vision. They are found in many species including rats, dogs, and humans. Vision is hindered where this "cloudiness", made of water build up and broken crystalline, proteins take form. Oculvet is an eye medication, used by veterinarians, containing carnosine as its active ingredient. Topical application of carnosine is reported to be an effective treatment for the prevention and removal of pre-existing cataracts. For this experiment, Sprague- Dawley rats were anesthetized and exposed to ultraviolet radiation, UVB and UVC. They were divided into four groups (n = 32), three …
Simulation To Augment Standardized Patients In Obstetric Ultrasound Training, Scott Richard Guirlinger
Simulation To Augment Standardized Patients In Obstetric Ultrasound Training, Scott Richard Guirlinger
Computational Modeling & Simulation Engineering Theses & Dissertations
Standardized patients are actors used in medical training to teach and eval11atc clinical skills of students prior to their using these skills on an actual patient. Augmented Reality is a relatively new technology that can be used to augment standardized patients with abnonnalitie8 and pathologies that they cannot portray themselves as normal healthy human beings. In our project, we sought to augment standardized patients with a 12-week- old fetus in order to train and possibly evaluate medical students and professionals in performing obstetric ultrasound procedures and interpreting the corresponding ultrasound image results.
The software library ARToolkit provided the framework for …
Antimicrobial Activity Screening Of Recombinant And Synthetic Varasin A Defensin From The Hard Tick Dermacentor Variabilis Against Various Bacteria, Julia A. Sharp
Biological Sciences Theses & Dissertations
Hematophagous arthropods, such as ticks and mosquitoes, rely on their innate immune system for defense against pathogens ingested in a blood meal as well as those acquired through injury. In response to pathogen recognition, the production of antimicrobial peptides, such as defensin, is typically upregulated. Varisin, a defensin, is thought to be a key component in the immunocompetence of the hard tick D. variabilis against Borrelia burgdorferi, the causative agent of Lyme disease. To study the antimicrobial effects of varisin, recombinant varisin was expressed by both insect cells and E coli. Purification of the protein followed by enterokinase treatment yielded …
Teaching With Cultural Competence Requires Gender Sensitivity., Marna R. Greenberg Do, Mph, Facep, Jessica Pierog Do
Teaching With Cultural Competence Requires Gender Sensitivity., Marna R. Greenberg Do, Mph, Facep, Jessica Pierog Do
Department of Emergency Medicine
No abstract provided.
Teaching Case: Occipital Neuralgia In A Young Patient - Expert Commentary, Avi Ashkenazi
Teaching Case: Occipital Neuralgia In A Young Patient - Expert Commentary, Avi Ashkenazi
Department of Neurology Faculty Papers
Expert commentary on Carayannopoulos, AG. Teaching case: Occipital neuralgia in a young patient, 47(9):1367-1368, October 2007.
T Cells Expressing Allograft Inflammatory Factor 1 Display Increased Chemotaxis And Induce A Profibrotic Phenotype In Normal Fibroblasts In Vitro, Francesco Del Galdo M.D., Ph.D., Sergio A. Jimenez M.D.
T Cells Expressing Allograft Inflammatory Factor 1 Display Increased Chemotaxis And Induce A Profibrotic Phenotype In Normal Fibroblasts In Vitro, Francesco Del Galdo M.D., Ph.D., Sergio A. Jimenez M.D.
Department of Dermatology and Cutaneous Biology Faculty Papers
Objective. Allograft inflammatory factor 1 (AIF-1) was first identified in rat cardiac allografts undergoing chronic rejection. The vasculopathy of chronic allograft rejection is strikingly similar to that seen in patients with systemic sclerosis (SSc). We previously demonstrated AIF-1 expression in inflammatory cells infiltrating skin and lungs from SSc patients, but its role in SSc pathogenesis is unknown. The present study was undertaken to investigate the effects of AIF-1 on T cell migration and production of cytokines capable of modulating normal dermal fibroblast functions.
Methods. Stably transfected Jurkat T cells expressing 2 AIF-1 splicing variants were prepared, and their migration toward …
Acculturation, Gender, And Alcohol Use Among Mexican American College Students, Marcela Raffaelli, Rosalie A. Torres Stone, Maria I. Iturbide, Meredith Mcginley, Gustavo Carlo, Lisa J. Crockett
Acculturation, Gender, And Alcohol Use Among Mexican American College Students, Marcela Raffaelli, Rosalie A. Torres Stone, Maria I. Iturbide, Meredith Mcginley, Gustavo Carlo, Lisa J. Crockett
Department of Psychology: Faculty Publications
Prior research with non-college samples of Mexican Americans has demonstrated that gender moderates the association between acculturation and alcohol use. We replicated this finding in a college student sample and attempted to account for the differential impact of acculturation on Mexican American men and women by examining the mediating effects of social context, family conflict and psychological functioning. Participants were 148 Mexican Americans (67% female; M age 23 years) from three state universities in California and Texas who completed self-report surveys. In multivariate analyses controlling for age, maternal education, living situation, and site, linguistic acculturation was associated with increased alcohol …
The Evolutionary Origins Of Human Patience: Temporal Preferences In Chimpanzees, Bonobos, And Human Adults, Alexandra G. Rosati, Jeffrey R. Stevens, Brian Hare, Marc D. Hauser
The Evolutionary Origins Of Human Patience: Temporal Preferences In Chimpanzees, Bonobos, And Human Adults, Alexandra G. Rosati, Jeffrey R. Stevens, Brian Hare, Marc D. Hauser
Department of Psychology: Faculty Publications
To make adaptive choices, individuals must sometimes exhibit patience, forgoing immediate benefits to acquire more valuable future rewards [1–3]. Although humans account for future consequences when making temporal decisions [4], many animal species wait only a few seconds for delayed benefits [5– 10]. Current research thus suggests a phylogenetic gap between patient humans and impulsive, present-oriented animals [9, 11], a distinction with implications for our understanding of economic decision making [12] and the origins of human cooperation [13]. On the basis of a series of experimental results, we reject this conclusion. First, bonobos (Pan paniscus) and chimpanzees ( …
Toward A Population Health Model Of Segmented Assimilation: The Case Of Low Birth Weight In Los Angeles, Brian K. Finch, Nelson Lim, William Perez, D. Phuong Do
Toward A Population Health Model Of Segmented Assimilation: The Case Of Low Birth Weight In Los Angeles, Brian K. Finch, Nelson Lim, William Perez, D. Phuong Do
Faculty Publications
The authors adapt the segmented assimilation theory to a model population health, which posits that assimilation is actually harmful to migrants' health. The authors also specify models of individual and contextual factors to indirectly test the theory of segmented assimilation - a theory that posits interactions between individual and residential circumstances. Using Year 2000 vital statistics data merged with 2000 U.S. census data from Los Angeles County, the authors model the probability of being born low birth weight among the native and foreign born. Results confirm an immigrant advantage at the individual level and protective effects of immigrant coresidence at …
Unlv Magazine, Cate Weeks, Erin O'Donnell, Shane Bevell, Barbara Cloud, Joy Drohan, Adam Baer, Holly Ivy De Vore, Gian Galassi, Eric Leake
Unlv Magazine, Cate Weeks, Erin O'Donnell, Shane Bevell, Barbara Cloud, Joy Drohan, Adam Baer, Holly Ivy De Vore, Gian Galassi, Eric Leake
UNLV Magazine
No abstract provided.
Osmotic Demyelination Syndrome: Case Report, Mzee Ngunga, R. Harania, K. Hameed, J. O. Jowi
Osmotic Demyelination Syndrome: Case Report, Mzee Ngunga, R. Harania, K. Hameed, J. O. Jowi
Internal Medicine, East Africa
We present a 40 year old man who was admitted to the hospital with convulsions. His final diagnosis was osmotic demyelination syndrome (ODS).We discuss the diagnostic and management challenges and the possible complications of this rare diagnosis.
Lsu Health Sciences Center New Orleans Update, Larry H. Hollier Md
Lsu Health Sciences Center New Orleans Update, Larry H. Hollier Md
LSUHSC Hurricane Katrina Archive: Reports & Presentations
"LSU Health Sciences Center New Orleans Update" is a PowerPoint presentation of 52 slides presented by Larry H. Hollier, MD, FACS (Dean of the School of Medicine 2004-2007, Chancellor 2006-2021) to the LSUHSC Board of Supervisors in October 2007.
This presentation includes academic program updates, facilities updates, student enrollment numbers, and faculty recruitment details two years after Hurricane Katrina forced the temporary closure and relocation of LSU Health Sciences Center - New Orleans.
Lsuhsc Facilities Daily Update: October 2007, Lsuhsc Property And Facilities Management
Lsuhsc Facilities Daily Update: October 2007, Lsuhsc Property And Facilities Management
LSUHSC Facilities Daily Updates: 2007
LSUHSC Facilities Daily Updates from October 2007.
These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.
Lsuhsc Facilities Biweekly Update: October 2007, Lsuhsc Property And Facilities Management
Lsuhsc Facilities Biweekly Update: October 2007, Lsuhsc Property And Facilities Management
LSUHSC Facilities Biweekly Updates: 2007
LSUHSC Facilities Biweekly Updates from October 12 and 26, 2006.
These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.
Clinical Indicators For Success Of Misoprostol Treatment After Early Pregnancy Failure, Candace Robledo, J. Zhang, J Troendle, K. Barnhart, M. D. Creinin, C. Westhoff, X. Huang, M. Frederick
Clinical Indicators For Success Of Misoprostol Treatment After Early Pregnancy Failure, Candace Robledo, J. Zhang, J Troendle, K. Barnhart, M. D. Creinin, C. Westhoff, X. Huang, M. Frederick
School of Medicine Publications
Objective
To identify clinical indicators for success of misoprostol treatment after early pregnancy failure.
Methods
A total of 473 women with early pregnancy failure received 800 μg of vaginal misoprostol on treatment day 1. At the follow-up visit on day 3, a second dose was given if expulsion was incomplete. On day 8, vacuum aspiration was offered if expulsion had not occurred. Ultrasonography was used as gold standard for success. A Classification and Regression Tree analysis was undertaken to derive two decision trees for the success of misoprostol treatment on study days 3 and 8.
Results
Heavy bleeding after the …
Jefferson Alumni Bulletin – Volume 56, Number 4, Fall 2007
Jefferson Alumni Bulletin – Volume 56, Number 4, Fall 2007
The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)
Jefferson Alumni Bulletin – Volume 56, Number 4, Fall 2007
Dean’s Column: My Story; Page 2
Findings: Gene Therapy Used to Reverse Heart Failure in Animals, Colon Cancer: A Hormone Deficiency Disease, Breast Cancers More Aggressive in African Americans; Page 5
On Campus; Page 8
A Dedication to the Future of Clinical Care; Page 11
Class Notes; Page 26
In Memoriam; Page 30
Alumni Weekend; Page 32
Alumni Giving; Page 34
The Bulletin Celebrates 85 Years; Page 48
By the Numbers: Eighty Five…
Gender Differences In Acute Cardiac Care: Where It's Not., Marna R. Greenberg Do, Mph, Facep
Gender Differences In Acute Cardiac Care: Where It's Not., Marna R. Greenberg Do, Mph, Facep
Department of Emergency Medicine
No abstract provided.
A Standardized Orientation Course On Central Line Placement Leads To Persistent Knowledge Improvement., Andrew C. Miller Do
A Standardized Orientation Course On Central Line Placement Leads To Persistent Knowledge Improvement., Andrew C. Miller Do
Department of Emergency Medicine
No abstract provided.
Successful Cessation: Exploring Quit Attempts At Lehigh Valley Hopital's Tabacco Treatment Program., Suzanne L. Smith Bs, Rrt-Nps, Mba, Sharon Kimmel Mha, Phd, Ascepi, Rebecca Johnston Sn, Tas, Dianna Mulhern Ms, Lpc, Judith Sabino
Successful Cessation: Exploring Quit Attempts At Lehigh Valley Hopital's Tabacco Treatment Program., Suzanne L. Smith Bs, Rrt-Nps, Mba, Sharon Kimmel Mha, Phd, Ascepi, Rebecca Johnston Sn, Tas, Dianna Mulhern Ms, Lpc, Judith Sabino
Department of Emergency Medicine
No abstract provided.
Local And National Health Advancement Using The Power Of Sport In South Africa, Lisa Zook
Local And National Health Advancement Using The Power Of Sport In South Africa, Lisa Zook
Independent Study Project (ISP) Collection
South Africa currently suffers greatly from disease and poverty. In particular, the country has a remarkably high prevalence of HIV/AIDS. This study looks at how the popularity of sport is being used to combat these social and health concerns. Many believe the power of sport is one means by which educational messages can be communicated to the public. Over a period of one month, three different sports related non-governmental organizations (NGOs) were examined. Two of the organizations, PeacePlayers International, which uses basketball to teach HIV/AIDS education and personal development, and loveLife Games, which uses sport to attract youth to their …
The Realization Of The Rights To Health, Education And Social Welfare Among Disabled Youth In Ingwavuma And Bhambanana, Kwazulu Natal, Ali Mumford
Independent Study Project (ISP) Collection
This practicum based study was completed in an effort to explore the realization of the rights to health, education and social welfare for disabled children in Ingwavuma and Bhambana, KwaZulu Natal. Very little research has been done on disabled children in South Africa, and estimations of prevalence range from 3.3-6.4%. The absence of accurate data creates a situation where implementation of policy and delivery of services is slow and does not always address the most urgent needs. The new South Africa aimed to bring rights and freedom to all groups of people, but the question which this study attempts to …
Faith As A Means Of Healing: Traditional Medicine And The Ethiopian Orthodox Church In And Around Lalibela, Lauren Anderson
Faith As A Means Of Healing: Traditional Medicine And The Ethiopian Orthodox Church In And Around Lalibela, Lauren Anderson
Independent Study Project (ISP) Collection
This paper examines and explores the relationship between indigenous medical traditions in Ethiopia and the healing rituals of the Ethiopian Orthodox Church. The practices still upheld by the Church today are explored in depth as is the prevalence of debtera, church educated traditional healers in Ethiopia. The relationship between traditional and modern modes of medical treatment in Ethiopia is explored as well as the legitimacy of both church healing and alternative medicine worldwide. Present research into the benefits of complementary and alternative medicine (CAM) including mind/body healing is also examined.
Buscando La Luz: Changes In Partería And The Loss Of Feminine Autonomy In Oaxaca, Mexico, Hannah Ewert-Krocker
Buscando La Luz: Changes In Partería And The Loss Of Feminine Autonomy In Oaxaca, Mexico, Hannah Ewert-Krocker
Independent Study Project (ISP) Collection
Birth is one of the most fundamental moments of every human being’s life, and women have long been honored in the world’s societies as sacred and vital due to their important roles as life-givers. Because of the importance of birth in the lives and societies of human beings, birth and birthing practices can reveal many values of a culture and of the women within that culture and also demonstrate how and why those values are changing. The choices women make between traditional health care and more “modern” Western models are almost always influenced by the socio-economic and cultural conditions of …
Risk Factors For Hiv Transmission Among Hispanic Men Who Have Sex With Men In Atlanta, Valerie A. Hepburn, Denyse N. Nanan
Risk Factors For Hiv Transmission Among Hispanic Men Who Have Sex With Men In Atlanta, Valerie A. Hepburn, Denyse N. Nanan
Journal of the Georgia Public Health Association
This study assessed and compared demographic factors, psychosocial factors, health seeking behavior, and sexual practices of two convenience samples of Hispanic/Latino gay men and men who have sex with men (MSM) in the metropolitan Atlanta region. The aim was to obtain data on emerging HIV/AIDS patterns in this group. Bilingual surveys were conducted in 2000 and 2006 at local gay bars. Discrepancies observed between HIV/AIDS knowledge and sexual behaviors in 2000 were replicated in 2006. Contrary to expected improvements due to enhanced HIV/AIDS education and awareness, risk behavior for HIV/STDs increased significantly between 2000 and 2006. These findings should inform …
Versatile Applications Of Transcriptional Pulsing To Study Mrna Turnover In Mammalian Cells, Chyi-Ying A Chen, Yukiko Yamashita, Tsung-Cheng Chang, Akio Yamashita, Wenmiao Zhu, Zhenping Zhong, Ann-Bin Shyu
Versatile Applications Of Transcriptional Pulsing To Study Mrna Turnover In Mammalian Cells, Chyi-Ying A Chen, Yukiko Yamashita, Tsung-Cheng Chang, Akio Yamashita, Wenmiao Zhu, Zhenping Zhong, Ann-Bin Shyu
Faculty, Staff and Student Publications
Development of transcriptional pulsing approaches using the c-fos and Tet-off promoter systems greatly facilitated studies of mRNA turnover in mammalian cells. However, optimal protocols for these approaches vary for different cell types and/or physiological conditions, limiting their widespread application. In this study, we have further optimized transcriptional pulsing systems for different cell lines and developed new protocols to facilitate investigation of various aspects of mRNA turnover. We apply the Tet-off transcriptional pulsing strategy to investigate ARE-mediated mRNA decay in human erythroleukemic K562 cells arrested at various phases of the cell cycle by pharmacological inhibitors. This application facilitates studies of the …
Computational Identification And Functional Validation Of Regulatory Motifs In Cartilage-Expressed Genes, Sherri R Davies, Li-Wei Chang, Debabrata Patra, Xiaoyun Xing, Karen Posey, Jacqueline Hecht, Gary D Stormo, Linda J Sandell
Computational Identification And Functional Validation Of Regulatory Motifs In Cartilage-Expressed Genes, Sherri R Davies, Li-Wei Chang, Debabrata Patra, Xiaoyun Xing, Karen Posey, Jacqueline Hecht, Gary D Stormo, Linda J Sandell
Faculty, Staff and Student Publications
Chondrocyte gene regulation is important for the generation and maintenance of cartilage tissues. Several regulatory factors have been identified that play a role in chondrogenesis, including the positive transacting factors of the SOX family such as SOX9, SOX5, and SOX6, as well as negative transacting factors such as C/EBP and delta EF1. However, a complete understanding of the intricate regulatory network that governs the tissue-specific expression of cartilage genes is not yet available. We have taken a computational approach to identify cis-regulatory, transcription factor (TF) binding motifs in a set of cartilage characteristic genes to better define the transcriptional regulatory …