Medicine and Health Sciences Commons^™

Graduate Project To Explore Factors Affecting Completion Of Final Degree Requirements For A Master Degree In Nursing, Sharon Gentile

Theses and Graduate Projects

The purpose of this project was to explore issues that influence Master Degree completion as perceived by graduate nursing students, using focus groups. All eight graduate nursing student participants recently completed structured coursework, but had not submitted a final paper or project. Margaret Newman's Health as an Expanding Consciousness Nursing Theory was applied as the conceptual framework used to process the information obtained. Dialogue between moderator and participants occurred during accompaniment enabling valuable information to be elicited, and participants' personal clarification of concerns; therefore establishing praxis. Issues emerged related to adult learners seeking defined expectations and effective relationships with advisors. …

Evaluating Forensic Dna Evidence - A Day-Long Workshop, Dan E. Krane, William C. Thompson

Biological Sciences Faculty Publications

No abstract provided.

Enhancement Of Efficacy Of Prrsv Vaccines By Altering The Glycosylation Pattern Of Viral Glycoproteins, Asit K. Pattnaik

School of Veterinary and Biomedical Sciences: Faculty Publications

PRRSV, the causative agent of PRRS is of major economic significance to the pork industry in the USA and around the world. Current commercial vaccine does not provide adequate protection against PRRSV outbreaks. Therefore, there is an urgent need for development of more efficacious vaccine to combat PRRS. Our previous studies have suggested that (i) induction of neutralizing antibody response is an important correlate of evaluating the efficacy of a vaccine; (ii) neutralizing antibodies can be enhanced by hypoglycosylation of the major surface glycoprotein (GP5). While it is known that GP5 plays a prominent role in neutralizing antibody induction, it …

Characterization Of Mazfsa, An Endoribonuclease From Staphylococcus Aureus, Zhibiao Fu, Niles P. Donegan, Guido Memmi, Ambrose L. Cheung

Dartmouth Scholarship

The mazEF homologs of Staphylococcus aureus, designated mazEF(sa), have been shown to cotranscribe with the sigB operon under stress conditions. In this study, we showed that MazEF(Sa), as with their Escherichia coli counterparts, compose a toxin-antitoxin module wherein MazF(Sa) leads to rapid cell growth arrest and loss in viable CFU upon overexpression. MazF(Sa) is a novel sequence-specific endoribonuclease which cleaves mRNA to inhibit protein synthesis. Using ctpA mRNA as the model substrate both in vitro and in vivo, we demonstrated that MazF(Sa) cleaves single-strand RNA preferentially at the 5' side of the first U or 3' side of the second …

Inter- And Intra-Subject Variability: A Palatometric Study, Marybeth Corey Sanders

Theses and Dissertations

Electropalatometry (EPM) has proven to be a useful clinical and research tool for measuring tongue-to-palate contact. The goal of this study was to determine whether the development of a database of standardized palatometric articulation files is feasible by examining the variability which exists within and between speakers. Twenty standard American English dialect speakers were fitted with palatometer pseudopalates. Test stimuli were VCV nonsense words using a schwa in the initial position, the 15 palatal consonants, and three corner vowels, /a/, /i/, /u/. From these palatometric recordings a variability index was created to examine intra- and interspeaker variability. Different aspects of …

Dissociating Speech Perception And Comprehension At Reduced Levels Of Awareness, Matthew H Davis, Martin R Coleman, Anthony R Absalom, Jennifer M Rodd, Ingrid Johnsrude, Basil F Matta, Adrian M Owen, David K Menon

Brain and Mind Institute Researchers' Publications

We used functional MRI and the anesthetic agent propofol to assess the relationship among neural responses to speech, successful comprehension, and conscious awareness. Volunteers were scanned while listening to sentences containing ambiguous words, matched sentences without ambiguous words, and signal-correlated noise (SCN). During three scanning sessions, participants were nonsedated (awake), lightly sedated (a slowed response to conversation), and deeply sedated (no conversational response, rousable by loud command). Bilateral temporal-lobe responses for sentences compared with signal-correlated noise were observed at all three levels of sedation, although prefrontal and premotor responses to speech were absent at the deepest level of sedation. Additional …

Paraumbilical Collateral Veins On Mri As Possible Protection Against Portal Venous Thrombosis In Candidates For Liver Transplantation, Sachit Verma, Donald G. Mitchell, Yulia Lakhman, Diane Bergin, Ronald J. Dolin, Cataldo Doria, Laurence Parker

Department of Radiology Faculty Papers

Background: We retrospectively evaluate the potential protective influence of patent paraumblical vein (PUV) collaterals against portal vein (PV) thrombosis and reduced PV diameter in candidates for orthotopic liver transplant (OLT)

Methods: Dynamic 3D contrast-enhanced MRI at 1.5T was obtained in 309 patients with cirrhosis without evidence of malignancy. All MR studies were reviewed by one reader for PUV collaterals, PV thrombosis and PV diameter. Statistical analysis was performed by Fisher exact tests; 50 selected studies were reviewed independently by two additional readers to determine interobserver agreement via intraclass correlation coefficient (ICC).

Results: Patent PUV was noted in …

Improving The Teaching Skills Of Residents As Tutors/Facilitators And Addressing The Shortage Of Faculty Facilitators For Pbl Modules., Wasim Jafri, Khalid Mumtaz, William P. Burdick, Page S. Morahan, Rosslynne Freeman, Tabassum Zehra

Department of Continuing Professional Education

BACKGROUND:

Residents play an important role in teaching of medical undergraduate students. Despite their importance in teaching undergraduates they are not involved in any formal training in teaching and leadership skills. We aimed to compare the teaching skills of residents with faculty in facilitating small group Problem Based Learning (PBL) sessions.

METHODS:

This quasi experimental descriptive comparative research involved 5 postgraduate year 4 residents and five senior faculty members. The study was conducted with all phase III (Final year) students rotating in Gastroenterology. The residents and faculty members received brief training of one month in facilitation and core principles of …

Enzymatic Pathways Of The Brain Renin-Angiotensin System: Unsolved Problems And Continuing Challenges, Vardan T. Karamyan, Robert C. Speth

HPD Articles

The brain renin-angiotensin system continues to be enigmatic more than 40 years after the brain was first recognized to be a site of action of angiotensin II. This review focuses on the enzymatic pathways for the formation and degradation of the growing number of active angiotensins in the brain. A brief description and nomenclature of the peptidases involved in the processing of angiotensin peptides in the brain is given. Of primary interest is the array of enzymes that degrade radiolabeled angiotensins in receptor binding assays. This poses major challenges to studies of brain angiotensin receptors and it is debatable whether …

Using Art In Occupational Therapy With People Who Have Cancer: A Qualitative Case Study, Jennifer R. Dochod

Masters Theses

OBJECTIVE. To explore the role of art, with a small group of people who have cancer, as a means provide distraction from pain, to help express feelings, and to assist in making connections with others.

METHOD. Using a randomized sample from Gilda’s Club, a support center for those with cancer, in-house social workers recruited two participants to take part in a small group case study conducted by a master’s level occupational therapy student.

RESULTS. Two participants enrolled in the art class conducted by the researcher. Predetermined questions gathered through participant interviews and class discussions provided the data. Although the participant …

Prior Exercise And Antioxidant Supplementation: Effect On Oxidative Stress And Muscle Injury, Richard Bloomer, Michael Falvo, Brian Schilling, Webb Smith

Kinesiology and Nutrition Sciences Faculty Research

No abstract provided.

Clinical Skills Day: Preparing Third Year Medical Students For The Rural Rotation, Gwen Wagstrom Halaas, Therese M. Zink, Kathleen D. Brooks, J. Miller

Family Medicine Faculty Publications

Introduction: In order to prepare third year medical students in the Rural Physician Associate Program for a nine-month community-based continuity care experience in rural Minnesota, USA, a clinical skills day that featured human patient simulators and standardized patients was developed. Patients presenting with common urgent and routine primary-care problems were developed and presented using the objective structured clinical examination for teaching. The goals of the day were to: (1) distinguish urgent from non-urgent clinical presentation; (2) use clinical guidelines for making decisions; (3) communicate effectively in stressful situations; and (4) uncover a significant clinical issue with a different presenting complaint. …

Urgency Is A Non-Monotonic Function Of Pulse Rate, Frank A. Russo, Jeffery A. Jones

Psychology Faculty Publications

Magnitude estimation was used to assess the experience of urgency in pulse-train stimuli (pulsed white noise) ranging from 3.13 to 200 Hz. At low pulse rates, pulses were easily resolved. At high pulse rates, pulses fused together leading to a tonal sensation with a clear pitch level. Urgency ratings followed a nonmonotonic (polynomial) function with local maxima at 17.68 and 200 Hz. The same stimuli were also used in response time and pitch scaling experiments. Response times were negatively correlated with urgency ratings. Pitch scaling results indicated that urgency of pulse trains is mediated by the perceptual constructs of speed …

Nicotinamide Riboside Kinase Structures Reveal New Pathways To Nad+, Wolfram Tempel, Wael M. Rabeh, Katrina L. Bogan, Peter Belenky, Marzena Wojcik, Heather F. Seidle, Lyudmila Nedyalkova, Tianle Yang, Anthony A. Sauve, Hee-Won Park, Charles Brenner

Dartmouth Scholarship

The eukaryotic nicotinamide riboside kinase (Nrk) pathway, which is induced in response to nerve damage and promotes replicative life span in yeast, converts nicotinamide riboside to nicotinamide adenine dinucleotide (NAD+) by phosphorylation and adenylylation. Crystal structures of human Nrk1 bound to nucleoside and nucleotide substrates and products revealed an enzyme structurally similar to Rossmann fold metabolite kinases and allowed the identification of active site residues, which were shown to be essential for human Nrk1 and Nrk2 activity in vivo. Although the structures account for the 500-fold discrimination between nicotinamide riboside and pyrimidine nucleosides, no enzyme feature was identified to recognize …

Chromosomal Microdeletions And Genes' Functions: A Cluster Of Chromosomal Microdeletions And The Deleted Genes' Functions, David Tilstra Md, Kevin Martens, Inge Heulens, Sandra Meulemans

Articles

Hypotonia-cystinuria syndrome (HCS) is a recessive disorder caused by microdeletions of SLC3A1 and PREPL on chromosome 2p21. Patients present with generalized hypotonia at birth, failure to thrive, growth retardation and cystinuria type I. While the initially described HCS families live in small regions in Belgium and France, we have now identified HCS alleles in patients and carriers from the Netherlands, Italy, Canada and United States of America. Surprisingly, among the nine deletions detected in those patients, only one novel deletion was found. Furthermore, one previously described deletion was found six times, another twice. Finally, we have investigated the frequency of …

Healthnet News V.22:No.3 Fall 2007, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.

Nicotine Replacement And Behavioral Therapy For Smoking Cessation In Pregnancy, Cheryl A. Oncken

UCHC Articles - Research

Abstract

Background

This study examines whether adding nicotine replacement therapy (NRT) to cognitive behavioral therapy (CBT) for pregnant smokers increases rates of smoking cessation.

Methods

An open-label randomized trial (Baby Steps, n = 181) of CBT-only versus CBT+NRT (choice of patch, gum, or lozenge; 1:2 randomization) was used. Data were collected from 2003 through 2005; analyses were conducted in 2006 and 2007. Outcomes were biochemically validated self-reported smoking status at 7-weeks post-randomization, 38-weeks gestation, and 3-months postpartum.

Results

Women in the CBT+NRT arm were almost three times more likely than women in the CBT-only arm to have biochemically validated cessation …

V Is For Voluntary: Uptake Of Hiv Testing And Counseling In Mombasa District, Kenya, Julie Caplow

Independent Study Project (ISP) Collection

Voluntary counseling and testing (VCT) is a crucial HIV intervention strategy, promoting safe behavior, providing personalized support, and serving as an entry point for care and treatment. Experts agree that knowledge of HIV status should ideally be universal; however, as VCT is a voluntary service, certain challenges arise in promoting its uptake. Though Kenya has made remarkable headway in expanding its VCT provision, setting a leading example for the world, 80% of adult citizens still have never been tested. This project investigates the factors controlling the uptake of VCT in Mombasa district and seeks ways to reach more people with …

Mid-Atlantic Ethics Committee Newsletter, Fall 2007

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Com Outlook Fall 2007, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Knowledge Integration: The Iaims Experience At Lvh., Donald L. Levick Md, Linda M. Schwartz Mde, Ahip, Cm, Bryan G. Kane Md

Administration & Leadership

No abstract provided.

Diagnostic Classifications And Resource Utilization Of Decedents Served By The Department Of Veterans Affairs, Sonia A. Duffy, Laurel Copeland, Faith Hopp, Robert J. Zalenski

Social Work Faculty Publications

Background: Given the volume and cost of inpatient care during the last year of life, there is a critical need to identify patterns of dying as a means of planning end-of-life care services, especially for the growing number of older persons who receive services from the Veterans Health Administration (VHA).

Methods: A retrospective computerized record review was conducted of 20,933 VHA patients who died as inpatients between October 1, 2001 and September 30, 2002. Diagnoses were aggregated into one of five classification patterns of death and analyzed in terms of health care resource utilization (mean number of inpatient days and …

Febrile Response And Decrease In Circulating Lymphocytes Following Acute Infection Of White-Tailed Deer Fawns With Either A Bvdv1 Or A Bvdv2 Strain, Julia F. Ridpath, C. Scott Mark, Christopher C.L. Chase, Alanson C. Ridpath, John D. Neill

Veterinary and Biomedical Sciences Faculty Publications

Although commonly associated with infection in cattle, bovine viral diarrhea viruses (BVDV) also replicate in many domestic and wildlife species, including cervids. Bovine viral diarrhea viruses have been isolated from a number of cervids, including mule deer (Odocoileus hemionus), European roe deer (Capreolus capreolus), red deer (Cervus elaphus), white-tailed deer (Odocoileus virginianus), and mouse deer (Tragulus javanicus), but little information is available regarding clinical presentation and progression of infection in these species. In preliminary studies of experimental infection of deer with BVDV, researchers noted seroconversion but no clinical signs. In this study, we infected white-tailed deer fawns that were negative …

Air Toxics Under The Big Sky – A High School Science Teaching Tool, David Jones, Tony Ward, Diana Vanek, Nancy Marra, Curtis W. Noonan, Garon Smith, Earle Adams

Public and Community Health Sciences Faculty Publications

A project has been developed between Big Sky High School and The University of Montana (UM) which has brought together high school students and teachers, university scientists, and county environmental health officials in a multilayered research experience focusing on the collection and analysis of specific air toxics, and investigating their relationship to respiratory diseases. The Air Toxics Under the Big Sky project allows students to benefit from an independent experience linking science, research, and local environmental issues. We see this as a long term project which will be built upon and expanded by future students during each new school year …

Predicting Academic Success In Undergraduates, Mary E. Pritchard, Gregory S. Wilson

Psychological Sciences Faculty Publications and Presentations

College academic success and retention have traditionally been predicted using demographic and academic variables. This study investigated the influence of student health on GPA and intent to drop out of college. A longitudinal survey of 242 freshmen revealed that emotional and social factors (e.g., stress, living in the dorm, being in a study group) predicted second semester GPA and intentions to drop out (e.g., perfectionism, fatigue). Implications for intervention strategies are discussed.

Client And Volunteer Satisfaction With The Povorello Medical Clinic, Syracuse University. Maxwell School. Community Benchmarks Program

Community Benchmarks Program

This report presents data collected from the Poverello Medical Clinic of the Franciscan Collaborative Ministries. Two surveys were administered, one assessed client satisfaction and the second volunteer satisfaction. The information provided will help the medical clinic to meet client needs and to maintain the continued support of the volunteers.

Use Of The §1915 (C) Federal Waiver Application: The Experience Of Eight States, Maureen Booth Mrp, Ma, Julie T. Fralich Mba, Hilary Skillings

Disability & Aging

Research staff at the Muskie School of Public Service, USM were requested to evaluate the effectiveness of the revised HCBS waiver application process from the perspective of states. This report summarizes the purpose, scope, approach and findings of the evaluation. The evaluation was designed to provide qualitative information on states' experience using the new HCBS waiver application for initial and renewal waiver applications. The evaluation examined four major issues:

Clarity/Consistency

: Are the waiver application components (Application, Technical Guide, Review Criteria) clearly understood and do they promote consistent interpretation?

Relevancy/Adequacy

:Do the application components address the range of waivers and …

What Do Adolescents Know About Health?, Christy Zenner, Mary Pritchard

Psychological Sciences Faculty Publications and Presentations

The purpose of this study was to investigate what adolescents know about topies commonly covered in Health classes (eating disorders, exercise, nutrition, caffeine, and sleep) and whether students know aS much as they think thtey do about these topics. We found that 9% of the students correctly answered all of the exercise questions, 2% nutrition, 2% sleep, 3% caffeine, and 5% eating disorders. Participants did believe they knew more about their health than they actually did. Results suggest that knowledge can clearly be improved.

Ada News - 10/01/2007, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

A Review Of The Literature On End-Of-Life Care: Setting A Research Agenda For Maine, Julie T. Fralich Mba, Jennifer D. Lenardson Mhs, Hillary Skillings

Disability & Aging

In 2002, Last Acts, a national campaign of the Robert Wood Johnson Foundation, issued a report assessing the states on access to end-of-life care and policies supporting its provision. Quite striking for the hospice providers and other stakeholders of Maine, the state ranked second to last in hospice use among persons over age 65 in their last year of life. Although anecdotal and unpublished data suggest that hospice use is on the rise in Maine, concerns about the low use rate remains a concern to those interested in end-of-life care in the State.

In order to better understand the factors …