Medicine and Health Sciences Commons^™

Multidrug-Resistant Esbl-Producing Escherichia Coli Coexisting With Colistin-Resistance Genes In Pig Farms, Central Thailand, Wipawee Songsaeng, Nutthee Am-In, Nuvee Prapasarakul, Wandee Sirichokchatchawan

The Thai Journal of Veterinary Medicine

The presence of extended-spectrum beta-lactamase and colistin resistance E. coli in food-producing animals is a public health concern. This study was conducted using a rigorous methodology to survey the prevalence of ESBL-producing and colistin-resistant E. coli from pig farms in the central part of Thailand. A total of 519 samples were collected from fecal, feed, and waste in 53 farms located in central Thailand. All samples were inoculated onto selective agar, and species identification was performed using biochemical assays and MAlDI-TOF MS. Antimicrobial susceptibility was determined by broth microdilution, and ESBL production was confirmed by the combination disc diffusion method. …

A Preliminary Study Of Lasia Spinosa Thw. Feed Supplementation Improving Semen Quality Of Subfertile Purebred Boars, Supitcha Kaewma, Junpen Suwimonteerabutr, Nutthee Am-In, Saritvich Panyaboriban, Mongkol Techakumphu, Theerawat Swangchan-Uthai

The Thai Journal of Veterinary Medicine

Poor semen quality is a significant issue among imported purebred boars in Thailand, affecting both semen quality itself and reducing productivity at AI stations. The present study investigated the effects of dietary supplementation with Lasia spinosa Thw. (LST) on improving boar semen quality. A group of boars experiencing poor semen quality were monitored, and three were selected due to their persistent low semen profiles for the supplementation experiment. Dried LST powder was prepared in small bags at a dosage of 4 g per 100 kg body weight and added to the regular feed for daily oral administration over an 8-week …

Quantitative Evaluation Of Different Fixatives For Masson Trichrome Staining In Canine Intestinal Tissue: An Image Analysis-Based Comparative Study, Siriluck Juntausa, Kongkiat Srisuwatanasagul, Kittipot Kongsonthana, Punnarat Vibulchan, Sayamon Srisuwatanasagul

The Thai Journal of Veterinary Medicine

Neutral buffer formalin (NBF) has been widely used as a fixative for histological staining for ages. However, for some special staining, such as Masson trichrome staining, it has been proposed that the suitable fixative was Bouin’s solution. The purpose of the present study was to compare the different fixatives and post-fixative protocols on the quality of Masson trichrome staining. The canine intestines (n = 10), which were the duodenum and colon, were used as the candidate organs since they comprised of various tissue components. The fixatives and staining protocols were divided into four groups, which were Groups 1 and 2; …

Metabolite Biomarker Discovery For Lung Cancer Using Machine Learning, Ariski Fajarido, Linda Erlina, Aryo Tedjo, Fadilah Fadilah, Wawaimuli Arozal

Indonesian Journal of Medical Chemistry and Bioinformatics

Lung cancer is the leading cause of cancer death worldwide. About 2.1 million lung cancer patients were diagnosed in 2018, accounting for about 11.6% of all newly diagnosed cancer cases. For lung cancer, blood is the first choice as a source of screening biomarker candidates. Blood biomarkers provide a snapshot of the patient's entire body, including the primary tumor, metastatic disease, immune response, and peritumoral stroma. However, sputum sampling, bronchial lavage or aspiration, exhaled breath (EB), and airway epithelial sampling represent unique samples for lung cancer and other airway cancers as potential sources for alternative biomarkers. Metabolites are products of …

Complete Dose Of Hepatitis B Vaccination Among Children In Indonesia And Factors Associated: A Community-Based Study, Putri Bungsu Machmud, Dwi Gayatri, Erni Astutik

Kesmas

Hepatitis B vaccination is widely recognized as the most effective way to prevent hepatitis B infection, yet the rate of complete vaccination among Indonesian children remains low. This study aimed to evaluate the extent of hepatitis B vaccination coverage among children and identify potential associated factors in Indonesia. A community-based cross-sectional study was conducted. The study involved 7,860 Indonesian mothers of children aged 12-59 months, providing data on their children's hepatitis B vaccination status and other relevant factors from the 2017 Indonesian Demographic Health Survey. Overall, the rate of complete hepatitis B vaccination among children was relatively high (89.8%). Several …

Exploration Of Positive Deviance In Prevention Of Underweight In The Under-Five: A Qualitative Study On Low-Income Urban Families, Irwan Budiono, Lukman Fauzi, Dewi Sari Rochmayani

Kesmas

Children under the age of five (the under-five) from low-income families are more vulnerable to experience underweight. This nutritional vulnerability is evident in the preliminary study, where 35.1% of the under-five experience underweight, and 28.48% are low-income families. This study aimed to explore Positive Deviance (PD) behaviors in preventing underweight among the under-five. The study applied a qualitative approach with a case study design. Data collection took place in July-August 2022, focusing on low-income families in the Gunung Brintik area. Data were collected through two focus group discussions, seven in-depth interviews, and five key informant interviews. Coding, subtheme, and theme …

Exploring Informal Caregivers’ Perspectives On Oral Care For Stroke Patients, Haslina Rani, Saidatul Najibah Muhammad Zamzuri, Ezzah Omar, Tuti Ningseh Mohd-Dom, Aznida Firzah Abdul Aziz, Mohd Fairuz Ali

Kesmas

Stroke often results in physical disability and functional impairment, which may severely limit patients' ability to care for personal hygiene, including oral care. This study aimed to identify the challenges faced by informal caregivers in managing the oral health of stroke patients. This study conducted semi-structured individual interviews with eight home-based caregivers of stroke patients recruited from a community-based clinic facility of a public university in Malaysia. The interviews took 30-45 minutes to complete and were transcribed verbatim. Transcripts were analyzed thematically using a phenomenological approach. Relevant themes that emerged were variations in oral hygiene care, caregivers’ concerns in providing …

Risk Factors For Cognitive Impairment In Adult Population Of Coastal Area: A Cross-Sectional Study In Maringkik Island, Indonesia, Herpan Syafii Harahap, Arina Windri Rivarti, Nurhidayati Nurhidayati, Fitriannisa Faradina Zubaidi, Dini Suryani, Legis Ocktaviana Saputri, Yanna Indrayana, Athalita Andhera, Muhammad Hilam, Abiyyu Didar Haq

Kesmas

Cognitive impairment is a medical condition commonly found in elderly populations, which can be due to vascular risk factors in patients. There remains limited data on risk factors for cognitive impairment among coastal region populations. This study aimed to investigate risk factors for cognitive impairment in the adult population of Maringkik Island, West Nusa Tenggara Province, Indonesia. Data collected were age, sex, education level, hypertension, antihypertensive treatment, diabetes mellitus, cigarette smoking, and body mass index status. A total of 114 participants were recruited using a consecutive sampling method. The participants’ cognitive function assessment used the Mini-Cog instrument. The cognitive impairment …

Food Hygiene And Sanitation At The Jakarta Pondok Gede Hajj Embarkation Dormitory: Food Safety Efforts For The Hajj Pilgrims, Fauziah Hayati, Al Asyary, Bambang Wispriyono, Harunor Rashid, Z Memish

Kesmas

Several health risks are associated with performing Hajj pilgrimage. Food poisoning is a major cause of diarrhea and vomiting during Hajj. Food hygiene is an effort to control aspects of food, people, places, and equipment that could cause disease or health problems. This study aimed to describe food hygiene and sanitation efforts implemented in 2023 at the Jakarta Pondok Gede Hajj Embarkation Dormitory in Jakarta, implemented in 2023 to safeguard foods for the Hajj pilgrims. Using a descriptive qualitative design with a document analysis approach, this study examined activities during the pre-embarkation and embarkation periods. Pre-embarkation efforts included inspecting the …

Variation And Predictors Of Covid-19 Mortality In Hospitalized Cases In West Sumatra Province, Indonesia: A Retrospective Observational Study, Defriman Djafri, Ade Suzana Eka Putri, Yudi Pradipta

Kesmas

During 2020, the year of the COVID-19 pandemic, different Indonesian provinces had different numbers of COVID-19 infections and fatalities, particularly in West Sumatra Province. This study aimed to investigate the variation of confirmed COVID-19 cases and determine predictors of mortality in hospitalized patients across districts in West Sumatra Province. A retrospective observational study was conducted during the COVID-19 pandemic. From March 2020 to June 2021, 46,005 confirmed cases were collected in the province, of which 42,308 were hospitalized and analyzed. Confirmed cases and deaths were compared by geographic location using spatial analysis. The risk predictors of death were estimated using …

The Open Defecation Free Program Evaluation Using The Context, Input, Process, And Product Model In Jambi, Indonesia, Guspianto Guspianto, Willia Novita Eka Rini, Rizalia Wardiah, Susi Desmaryani, Herlina Herlina

Kesmas

The Open Defecation Free (ODF) program was initiated by the government to increase access to healthy latrines. This study aimed to evaluate the ODF program using the CIPP evaluation model. A qualitative and exploratory descriptive method was adopted to investigate informants' experiences regarding the program's implementation. Data was explored through semi-structured interviews with 17 informants and analyzed using content analysis. The results showed that the program was crucial as numerous people engaged in open defecation due to economic, geographical, cultural, and knowledge factors. The absence of ODF policy was due to lack of priority, limited government and private support, insufficient …

“Two Is Company, Three Is A Crowd” – A Case Presentation Of Cardiac Amyloidosis, Hypertrophic Cardiomyopathy Plus Coronary Heart Disease, ​Carolina Miguel Gonçalves, Mariana Carvalho, Celia Domingues, Fatima Saraiva, ​​Joao ​ ​​Morais​

Journal of the Saudi Heart Association

A 76-year-old man was referred to our appointment with complaints of exertional dyspnea. He had a medical history consisting of chronic coronary syndrome, hypertrophic cardiomyopathy, and an implantable cardioverter-defibrillator for primary prevention. A transthoracic echocardiogram revealed features suspicious for cardiac amyloidosis. Haematologic and genetic tests were negative, and scintigraphy was positive, confirming wild-type transthyretin amyloidosis, not eligible for tafamidis. Several months later with optimized medical therapy, he had two worsening heart failure events.

This clinical case highlights the importance of differential diagnosis. Our patient had both hypertrophic cardiomyopathy and transthyretin amyloidosis, a rare association that constitutes a diagnostic and treatment …

The Potential Renoprotective Effects Of Ticagrelor In Rhabdomyolysis-Induced Acute Kidney Injury In Rat, Zahraa Talib Hussein, Ayad Ali Hussein

Maaen Journal for Medical Sciences

Background: Rhabdomyolysis is a potentially lethal range of symptoms results from muscle cell destruction. It is recognized by the escape of cell contents such as myoglobin, creatine kinase, and electrolyte into the bloodstream then undergo glomeruli filtering. Therefore, among the most dangerous complication of rhabdomyolysis is acute renal injury. The complex and interrelated processes underlying rhabdomyolysis that ends with acute kidney injury include obstruction and damage of tubules, inflammation, and intrarenal vasoconstriction (activation of the sympathetic, renin-angiotensin).Glycerol is frequently used to inflict this kind of harm when used as a single dose injection that given intramuscularly to an animal …

Heartmate 3 As A Bridge To Transplant In An Adult With Failing Fontan Circulation, Kengo Z. Soghoyan, Stephen Cook, Maya Guglin

The VAD Journal

Mechanical circulatory support devices have demonstrated efficacy in adult congenital patients with biventricular repairs. The off-label use of ventricular assist devices may be invaluable for managing end-stage single ventricle failure. We present the case of a 27-year-old male who developed heart failure, congestive hepatopathy, and, ultimately, cardiogenic shock. He received a HeartMate 3 (Abbott, Chicago, IL, USA) without complications one year after the surgery.

Saudi Heart Association / National Heart Center / Saudi Arabian Cardiac Interventional Society / Saudi Society For Cardiac Surgeons / Saudi Cardiac Imaging Group 2023 Tavi Guidelines, Turki Albacker, Adel Tash, Hussein Alamri, Mirvat Alasnag, Wail Alkashkari, Fawaz Almutairi, Faisal Alqoofi, Ahmed Alsaileek, Uthman Aluthman, Ghormallah Alzahrani, Mohammed Balghith, Fahd Makhdom

Journal of the Saudi Heart Association

Saudi Arabia has seen a significant improvement in its healthcare system over the past four decades resulting in an increase in life-expectancy. Transcatheter aortic valve implantation (TAVI) has spread widely in Saudi Arabia and has become a routine procedure in many centers. The expanding clinical indications and the availability of the technology have made it possible for many large and intermediate centers all over the country to commence their own TAVI programs. So, the aim of this document is to standardize TAVI practices in different Saudi Arabian centers through reasonable guidelines based on the evaluation and summarization of the best …

Team-Centered Care After Trauma Patient Death: Promoting Healers’ Healing By Humanizing Our Roles, Sydni Au Hoy, Carlie J. Arbaugh, Caitlin P. Bungo, Amanda J. Deutsch, Bonnie E. Chow, Kristen Gallegos, Nerissa Alansalon, Emmanuel Jisrawi, Al’Ai Alvarez, Brooke Gurland, Joseph Forrester

Journal of Wellness

Introduction: Recurrent exposures to adverse patient events, including death, affect all members of the care team and can have long-term effects on clinician performance, personal well-being, and patient safety. Recognizing the impact of patient deaths on care teams is essential to mitigating potential risks of increased clinician burnout. We share the outcomes of a three-month pilot wellness intervention implemented at a busy academic hospital, directed explicitly toward resuscitation care teams managing patients who die from traumatic injuries.

Approach: A collaborative group from Stanford’s Trauma Surgery, Emergency Department (ED), and well-being leadership developed an integrated workflow to connect with …

Teacher Implementation Profiles: A Response To Top-Down Mandate Of Movement Integration, Zack Beddoes, Jeanne Barcelona, Darla Castelli

International Journal of Physical Activity and Health

This study examined teacher implementation practices to meet a state mandate requiring 135 minutes of student physical activity (PA) weekly. Teachers were required to implement a video-based movement integration (MI) program. Using an embedded mixed-methods design, provider characteristics of 42 teachers and the organizational capacity of six schools were developed from interviews, surveys, observations, and artifacts. Data analysis revealed three teacher profiles (a) Dynamic Experientialists, (b) Coachable Constructivists, and (c) Cautious Behaviorists, and three school profiles (a) Whole Child Approach, (b) Grade Level Champions, and (c) Back to Basics. Findings suggest that school, teacher, …

Socioeconomic Status, Physical Inactivity, And Bmi In Transitional Urban China: Contextualizing The Theory Of Fundamental Causes, Jun Xu, Fang Gong, Wei Zhao

International Journal of Physical Activity and Health

Drawing insights from the theory of fundamental causes of disease, this study examined the relationships between socioeconomic status (SES) and selected risk factors in transitional urban China. Specifically, under China’s distinct institutional and sociocultural environment, we examined how contextualized SES (i.e., party membership, hukou status, housing ownership, and subjective social status) and conventional SES indicators (i.e., education, income, and occupation) were associated with physical inactivity and body mass index (BMI). Utilizing the urban subsample of the 2017 Chinese General Social Survey (CGSS), we found that individuals with higher education, income, Communist Party membership, and urban hukou status had lower risks …

Cell-Based Medicinal Products: Progress And Perspectives, Lijian Hui, Xiang Yuan, Jingqi Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Cell-based medicinal products are a breakthrough that has been proven to treat previously incurable diseases, making them a topic of global interest. This review delves into the current state and progress of cell therapy, highlighting the remarkable therapeutic effects of various types of cell-based medicinal products. We specifically explore the potential development of cell-based medicinal products in China, focusing on promoting clinical translation and commercialization. We propose necessary actions to achieve these goals, such as fostering cutting-edge basic research, innovative therapeutic approaches, scalable manufacturing processes, and policy changes.

Comprehensive Technical Analysis Of A Kickboxing Fight In K1 Format Based On Observation, Marta Niewczas, Wojciech Wąsacz, Wiesław Chwała, Tomasz Pałka, Ewa Sobiło-Rydzik, Tadeusz Ambroży, Kristína Němá, Łukasz Rydzik

Baltic Journal of Health and Physical Activity

Introduction: Observation and specialized analysis of confrontations in combat sports are fundamental for introducing corrections in training programs and for modifying the individual technical-tactical profiles of athletes in these types of activities. These actions comprehensively assess the progress of sports activities, ultimately inspiring and guiding the direction of training in sports clubs. The aim of this study was to analyze and assess the level of the offensive structure of Kickboxing sport fights in the K1 format, in terms of global simulated sparring, in selected thematic sets. Materials and Methods: The research material consisted of a multimedia recording of 10 simulated …

Interprofessional Collaboration As A Feminist Pedagogy: A Call For The Unsettling Of Care In Health Professions Education, Ivana Guarrasi, Rhonda Cornell, Sally Clemenson

Feminist Pedagogy

No abstract provided.

The Why, The Who, And The How: Launching The Society Of Critical Care Cardiology, Balimkiz Senman, David M. Dudzinski, Ann Gage, P. Elliott Miller, Jason N. Katz

Journal of Shock and Hemodynamics

None.

Parkinson’S Disease: Traditional And Emerging Approaches To Therapy, Emily Vernon

The Kabod

Honors Petition submitted to NURS 306: Pharmacology.II.

Natural Remedy Use During Pregnancy, Labor, And Breastfeeding, Christine Lyford

The Kabod

Honors Petition submitted to NURS 306: Pharmacology.

To Heal A Mind: A Functional Approach To The Treatment Of Major Depressive Disorder, Gillian Chambers

The Kabod

Honors Petition submitted to NURS 306: Pharmacology II.

Companion Dogs And Depression, Anxiety, And Posttraumatic Stress Disorder In Adult Icu Survivors: A Scoping Review, Lindsey Nelson, Sue Lasiter, Amanda Emerson

People and Animals: The International Journal of Research and Practice

Intensive care unit (ICU) survivors are at risk for developing persistent psychological sequelae that have been linked to decreased quality of life and increased mortality after hospital discharge. Standardized evidence-based treatments are lacking, mainly focus on physical rather than psychological recovery, and often occur in formal settings. Benefits of human– companion dog relationships have not been explored in the ICU survivor population before. Thus, the purposes of our review were to summarize the literature focused on the influence of companion dogs on depression, anxiety, and posttraumatic stress disorder (PTSD); identify what is known about the potential role companion dogs play …

Relationship Between Parental Involvement And Infant Bonding Among Families Of Barangay Tambacan, Tubod, And Santiago, Iligan City, Samantha Colegado Templado, Jezneel C. Cale, Ian C. Abordo Phd, Donna Belle P. Sumugat Rn, Man, Ma. Almira P. Nebres Rn, Man, Phd, Angelica N. Sarsaba

Pacific Journal of Health

Background and Aim: This study explored and assesses the extent of parental involvement and its relationship to infant bonding. It aimed to determine how varying levels of engagement from parents influence the development of a strong bond with their infants.

Design: We employed a descriptive correlational design and utilized questionnaires to collect data from 150 families living in Iligan City. Respondents were specifically from squatter areas of Iligan City.

Results: The findings of this study reveal that fathers tend to show indirect care that happens monthly, which relates to the infant’s soothing level. Mothers generally understand their infants' basic mental …

Cost-Utility Analysis Of Adding Daratumumab To Bortezomib Plus Dexamethasone To Treat Relapsed/Refractory Multiple Myeloma In Egypt, Menna M. Elsherbiny, Ahmed M. Kamel, Samar F. Farid

Bulletin of Faculty of Pharmacy Cairo University

Background: According to the CASTOR trial, DARA is shown to be effective as a second line for RRMM patients either as monotherapy or in combination with the gold standard regimen. The current study is the first to evaluate the cost-effectiveness of DARA based on the full results (~80-month follow-up) of the CASTOR trial. The study aimed to assess the cost-effectiveness of incorporating DARA, with bortezomib and dexamethasone, in treating patients from the perspective of a healthcare payer over a lifetime horizon.

Methods: A partition survival model (PSM) was adopted. The alternative arms chosen were daratumumab added to bortezomib plus …

Yoga As A Didactic Tool For Musculoskeletal Anatomy For First Year Medical Students, Jennnifer Brueckner-Collins, Scott P. Stuckey

Journal of Wellness

Introduction: Medical education requires students to adjust their study habits. Active learning has been shown to enhance understanding, especially regarding anatomy. Wellness has become increasingly emphasized for medical professionals; thus, it is important for medical students to develop wellness habits to mitigate burnout. Yoga is commonly practiced with a focus on wellness and flow of movements. Yoga as an educational and wellness tool integrated into medical gross anatomy is a worthwhile pursuit. This study describes a series of anatomy-based yoga videos designed to meld wellness activities with musculoskeletal anatomy review for preclinical medical students.

Approach: Six novel yoga …

Tirzepatide Protects Against Hepatic Oxidative Stress In High-Fat Induced Obesity In Male Rats, Ashraf Jameel Alathary, Zahraa Jawad Kadhim

Maaen Journal for Medical Sciences

Background

Obesity is a prevalent health issue that affects people of all ages at a high rate. Tirzepatide (TZP) is a hypoglycemic medication that acts as a dual antagonist for both the GIP-1 and GIP receptors. Previous reports have shown that TZP treatment demonstrated substantial weight reduction as well as lipid-modulating effects in obese and overweight individuals.

Objective

The aim from this study is to examine the potential protective effect of TZP on oxidative stress status and HFD induced obesity in male rats.

Methods

This research employed a total of 28 adult male Sprague-Dawley rats. Normal control group involved seven …