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Chulalongkorn Medical Journal

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Full-Text Articles in Medicine and Health Sciences

Application Of Roy's Adaptation Model In Nursing Care For Patients With End Stage Renal Disease Requiring Hemodialysis, K Yodchai, A Oumtanee, Y Matchim, N. Niyomthai May 2011

Application Of Roy's Adaptation Model In Nursing Care For Patients With End Stage Renal Disease Requiring Hemodialysis, K Yodchai, A Oumtanee, Y Matchim, N. Niyomthai

Chulalongkorn Medical Journal

This article details an application of Roy’s Adaptation Model (RAM) in providing nursing care for patients with end stage renal disease (ESRD) experiencing changes associated with required haemodialysis (HD). RAM guides the assessment of the patients’ levels of adaptation and facilitates the management of stimuli to promote their adaptation. The nursing intervention focuses on issues surrounding the adverse effects of HD treatment including physical, psychological, and social changes.


Stress And Associated Factors Among Ruamkatanyu Rescue Workers In Bangkok Mmetropolis, P Somboon, C. Roomruangwong May 2011

Stress And Associated Factors Among Ruamkatanyu Rescue Workers In Bangkok Mmetropolis, P Somboon, C. Roomruangwong

Chulalongkorn Medical Journal

Background : Ruamkatanyu rescue workers is a special properties and especial individual occupation. They are working with injured and emergency patients which may have additional work danger that have effect on physical, emotional and any pressure. However, the prevalence and predictors of stress in this group of subject have not been studied. This aim of study was to assess the prevalence and risk factors of stress among Ruamkatanyu rescue workers in Bangkok Metropolis. Objective : To study stress and associated factors among Ruamkatanyu rescue workers in Bangkok Metropolis. Design : A cross – sectional descriptive study. Setting : Ruamkatanyu rescue …


Characteristics Of Gafchromictm Ebt Film For Dosimetric Verification For High Energy Photon Beams, P Wongjom, S Suriyapee, T Sanghangthum, S Oonsiri, P. Insang May 2011

Characteristics Of Gafchromictm Ebt Film For Dosimetric Verification For High Energy Photon Beams, P Wongjom, S Suriyapee, T Sanghangthum, S Oonsiri, P. Insang

Chulalongkorn Medical Journal

Objective : The objectives of this research are to study the characteristics of GafchromicTM EBT film for 6 MV x-ray beams and to verify isodose distribution of advanced radiation treatment techniques. Study design : Observational descriptive study. Setting : Division of Therapeutic Radiology and Oncology, Department of Radiology, Faculty of Medicine, Chulalongkorn University. Materials and Methods : The characteristics of Epson perfection V700 flat-bed color CCD were observed for the response, the repeatability, the reproducibility and color band. The characteristics of GafchromicTM EBT film were studied for speed of film development, polarization, uniformity, field size and dose rate effects. The …


Sufficient Activity Is Important For Mobility Of Well-Functioning Elderly, S Amatachaya, T Thaweewannakij, K Srisim, S Wongsa, K Phiwjinda, L Mato, W. Siritarathiwat May 2011

Sufficient Activity Is Important For Mobility Of Well-Functioning Elderly, S Amatachaya, T Thaweewannakij, K Srisim, S Wongsa, K Phiwjinda, L Mato, W. Siritarathiwat

Chulalongkorn Medical Journal

Background : The number of the elderly has been increasing but most of them are not sufficiently active. Thus the information to confirm the importance of sufficient mobility is crucial in order to delay impaired movements and decrease the number of dependent individuals. Objective : To investigate the differences of walking speed and distance, balance control and falls of sufficiently active (exercise and lifestyle active) and the eldery who are not sufficiently active. Setting : Several communities in Khon Kaen province. Research design : A cross-sectional study Subjects : One-hundred and fifty well-functioning elderly, aged 65 - 80 years old. …


Catch-Up Growth In A Girl With Prolonged Autoimmune Hypothyroidism Complicated By Precocious Puberty After Thyroid Hormone Replacement, V Supornsilchai, C Kongkanka, S. Wacharasindhu May 2011

Catch-Up Growth In A Girl With Prolonged Autoimmune Hypothyroidism Complicated By Precocious Puberty After Thyroid Hormone Replacement, V Supornsilchai, C Kongkanka, S. Wacharasindhu

Chulalongkorn Medical Journal

Decreased height velocity (HV), one of the clinical manifestations of hypothyroidism which is completely reversed by appropriate thyroid hormone replacement, is called catchup growth. The objective of this report is to determine the longitudinal growth of a girl with prolonged hypothyroidism due to Hashimoto's thyroiditis complicated by precocious puberty. A 9-year-and-6-month-old girl presented with vaginal bleeding, growth failure and the typical physical signs of hypothyroidism due to Hashimoto's thyroiditis. She received Eltroxin replacement. The height has gained a total of 33 cm during 2 years and 6 months of treatment without additional treatment by GnRHa or any combination of GH …


Common Ct Findings Of Cholangiocarcinoma At King Chulalongkorn Memorial Hospital (Kcmh), C Paiboon, L Vajragupta, N. Tanpaopong Mar 2011

Common Ct Findings Of Cholangiocarcinoma At King Chulalongkorn Memorial Hospital (Kcmh), C Paiboon, L Vajragupta, N. Tanpaopong

Chulalongkorn Medical Journal

Background : We evaluated CT findings of 45 patients with cholangiocarcinomas. Objective To evaluate CT findings and pattern enhancement of cholangiocarcinoma at King Chulalongkorn Memorial Hospital (KCMH). Methods : The contrast-enhanced CT images of the abdomen of 45 patients (29 males, 16 females were retrospective reviewed. The mean age of the subject was 56 years. Their age range was 26-81 years old. The subject were pathologically proven cases of cholangiocarcinoma diagnosed from 2004-2006. The CT findings were analyzed as follows: (1) location and macroscopic appearance (mass-forming, periductal infiltrating, intraductal and extrahepatic cholangiocarcinoma); (2) tumor size; (3) pattern of enhancement; (4) …


Mental Health Problems Of New Thai Army Recruits In Phra Mongkutklao Hospital, P Khantong, C. Nimnuan Mar 2011

Mental Health Problems Of New Thai Army Recruits In Phra Mongkutklao Hospital, P Khantong, C. Nimnuan

Chulalongkorn Medical Journal

Problem/Background : Mental illness in Thai army privates has increased during last year. This problem costs the military a lot of health care budget. The researcher was therefore, interested to study mental health problems of the new Thai army recruits so that the obtained data can be used in promoting and preventing their mental health problems. Objective : To study mental health problems and related factors of the new Thai army recruits at Phra Mongkutklao Hospital in 2009. Research Design : Cross-sectional descriptive study. Setting : Phra Mongkutklao Hospital. Materials and Methods : The participants were 220 new Thai army …


Factors Affecting Depression In Workplace: Marital Status, Bmi, Stress Level, Work Duration, Job Pattern, And Daytime Sleepiness, K. Kongsomboon Mar 2011

Factors Affecting Depression In Workplace: Marital Status, Bmi, Stress Level, Work Duration, Job Pattern, And Daytime Sleepiness, K. Kongsomboon

Chulalongkorn Medical Journal

Background : It has been reported that Thai people have high prevalence of depression in workplace. Its impact is highest on individual-level effect of work performance. Employers who identify the risk factors and promote effective treatment may improve both the clinical and corporate outcomes. Objective : To determine risk factors of personnel's depression of the Faculty of Medicine of Srinakharinwirot University, consisted of career group, gender, age group, marital status, underlying disease, BMI, work time, work duration, sleep duration, excessive daytime sleepiness, job pattern, and stress level. Design : Cross-sectional study Material and Method : Staff and officers of the …


Effects Of Meloxicam And Etoricoxib On Blood Pressure And Vascular Reactivity In Rats, P Trongtorsak, S Sukpat, D Buapool, K. Thornola Mar 2011

Effects Of Meloxicam And Etoricoxib On Blood Pressure And Vascular Reactivity In Rats, P Trongtorsak, S Sukpat, D Buapool, K. Thornola

Chulalongkorn Medical Journal

Background : Treatment with selective cyclooxygenase-2 (COX-2) inhibitor is associated with increased risk of cardiovascular events. Inhibition of COX-2 reduces vascular prostacyclin synthesis without disrupting COX-1-derived thromboxane synthesis, which may alter vascular tone and responsiveness. Objective : To examine the effects of two COX-2 inhibitors, meloxicam and etoricoxib, on blood pressure and vascular reactivity in rats. Methods : Unconscious blood pressure was obtained from Sprague Dawley rats by a tail-cuff method, and then the rats were divided into 3 groups (n = 9 in all groups): 1) non - treated control, 2) meloxicam 1 mg/kg/d, 3) etoricoxib 3 mg/kg/d. Drugs …


Anti-R-Huepo Associated Pure Red Cell Aplasia: Information Update, K. Praditpornsilpa Mar 2011

Anti-R-Huepo Associated Pure Red Cell Aplasia: Information Update, K. Praditpornsilpa

Chulalongkorn Medical Journal

Recombinant Epo (r-HuEpo) ถูกสังเคราะห์เป็นยาที่ใช้รักษาภาวะซีดในผู้ป่วยไตวายเรื้อรังโดยกระบวนการ biotechnology การค้นพบยานี้ช่วยทำให้ผู้ป่วยไตวายเรื้อรังมีคุณภาพชีวิตที่ดี และมีอัตราการเกิด cardiovascular morbidity ลดลง ผู้ป่วยบางรายที่ได้รับยาอาจเกิดภาวะ pure red cellaplasia (PRCA) ซึ่งเกิดจาก anti-r-HuEpo antibody ทำให้เกิดภาวะซีดรุนแรงจนอาจทำให้เกิดภาวะแทรกซ้อนทางหัวใจและหลอดเลือดจนอาจทำให้ผู้ป่วยเสียชีวิต เกณฑ์ในการวินิจฉัยที่สำคัญที่สุดในการระบุภาวะ anti-r-HuEpo associated PRCA ได้แก่ การตรวจ anti-r-HuEpo และพิสูจน์พบว่าanti-r-HuEpo มี neutralization effect ด้วย neutralization assay ยังไม่ทราบสาเหตุของ anti-r-HuEpoassociated PRCA ที่แน่ชัด อย่างไรก็ตามมีสมมุติฐานที่น่าสนใจหลายสาเหตุ ได้แก่ สมมุติฐานleacheat therapy, บทบาทของ cold chain, และบทบาทของปัจจัยทางพันธุกรรม ปัจจุบันยังไม่มีการศึกษาในลักษณะ clinical trial ถึงแนวทางการรักษาผู้ป่วยภาวะ anti-r-HuEpo associated PRCAมีข้อแนะนำให้ผู้ป่วยทุกรายหยุดยา r-HuEpo โดยไม่ควรเปลี่ยนยี่ห้อผลิตภัณฑ์ และควรพิจารณาปลูกถ่ายไตแก่ผู้ป่วยในผู้ป่วยที่ไม่มีข้อห้าม ในผู้ป่วยที่ไม่สามารถปลูกถ่ายไตควรได้รับยากดภูมิคุ้มกันข้อมูลที่มีอยู่แสดงให้เห็นว่ายากดภูมิคุ้มกันอาจมีประสิทธิภาพในการรักษา ทั้งนี้ขึ้นกับ regimenในการใช้ยา.


Severity Of Methamphetamine Relapses Of Individuals Receiving Substance-Dependency Treatment At Thanyarak Institute, W Jitpong, V Verachai, R. Kalayasiri Mar 2011

Severity Of Methamphetamine Relapses Of Individuals Receiving Substance-Dependency Treatment At Thanyarak Institute, W Jitpong, V Verachai, R. Kalayasiri

Chulalongkorn Medical Journal

Objective : To study the severity relapse of methamphetamine or ya-ba use and its related factors. Methods : Data from 250 methamphetamine users who reported sustained cessation for at least one month but got relapse and receiving inpatient treatment at Thanyarak Institute was collected retrospectively by using three questionnaires, namely; 1) General Background Questionnaire; 2) Severity of Dependence Scale (SDS) Thai version; and 3) Mini International Neuropsychiatric Interview - lifetime (MINI-lifetime) Thai version. Demographics, family/social variables, diagnosis, and treatments were analyzed for association with methamphetamine relapse severity by using Chi-Squares test, Fisher’s Exact Test and logistic regression analysis. Results : …


Correlation Between Nerve Conduction Study (Ncs) And Clinical Improvement In Carpal Tunnel Syndrome (Cts), J Boonhong, K. Somsud Mar 2011

Correlation Between Nerve Conduction Study (Ncs) And Clinical Improvement In Carpal Tunnel Syndrome (Cts), J Boonhong, K. Somsud

Chulalongkorn Medical Journal

Objective : To determine the correlation between the changing of parameters of nerve conduction study (NCS) and clinical symptoms in carpal tunnel syndrome (CTS) patients after conservative treatments. Design : Retrospective study. Setting : Electrodiagnosis Laboratory Unit, the Department of Rehabilitation Medicine, King Chulalongkorn Memorial Hospital. Methods : All NCS reports from 1 Jan 2006 to 31 Dec 2008 were reviewed and studies that met the inclusion criteria were recruited into the study. All parameters of NCS included distal sensory latency (DSL), sensory nerve action potential (SNAP) amplitude, distal motor latency (DML) and compound muscle action potential (CMAP) amplitude of …


A Study Of Bacteria In Autopsy Room At Chulalongkorn Forensic Center, Faculty Of Medicine, Chulalongkorn University, G Thepsitthar, U Hoonwijit, Chatsuwant, S. Nilgate Mar 2011

A Study Of Bacteria In Autopsy Room At Chulalongkorn Forensic Center, Faculty Of Medicine, Chulalongkorn University, G Thepsitthar, U Hoonwijit, Chatsuwant, S. Nilgate

Chulalongkorn Medical Journal

Background : Postmortem culture of forensic cases shows some difficulty in interpretation. Many contaminated organisms may be isolated from the specimens. One of the most important sources of these contaminants may include the environment of the autopsy room. This study of bacteria culture in the autopsy room is therefore made in order to identify colonized bacteria which are able to contaminate in the forensic specimen. Objective : To identify colonized bacteria for assisting in interpretation of postmortem culture. Design : Descriptive study Setting : Department of Forensic Medicine, Faculty of Medicine, Chulalongkorn University. Materials and methods : Three areas of …


Reduction Of Stress, Depression And Overweight By Awareness Of Problems In Thai Medical Students, Srinakharinwirot University, K Kongsomboon, D. Pattarathitinan Jan 2011

Reduction Of Stress, Depression And Overweight By Awareness Of Problems In Thai Medical Students, Srinakharinwirot University, K Kongsomboon, D. Pattarathitinan

Chulalongkorn Medical Journal

Objective : To determine the effect of awareness in reducing the stress, depression and overweight in medical students of Srinakharinwirot University. Design : Cohort study. Materials and Methods : All 646 medical students of Srinakharinwirot University were recruited, and the response rate was 86%. The study was done from September 2007 to March 2008. Each participant was evaluated at twice; at the end of the first and second semester. The diagnostic screening test for depression was from the Department of Mental Health, Ministry of Public Health, Thailand and the stress test of Suanprung Hospital, Thailand. After evaluation at the end …


Clinical Application Of Pharmacogenetic Markers For Drug Dosing, C. Sukasem Jan 2011

Clinical Application Of Pharmacogenetic Markers For Drug Dosing, C. Sukasem

Chulalongkorn Medical Journal

Human polymorphic nature has an effect on individual drug response and adverse drug reactions (ADR). These variations include insertions, deletions, copy number variations and single nucleotide polymorphisms (SNPs) that affect gene expression and activity of drug metabolizing enzymes. Currently, there have been extensively studies and well characterized relationships between genetic variations and drug metabolism, and drug toxicity. Consequently, the application of patient genetic background to individualized therapy has been achieved at the practical level. Moreover, information on pharmacogenetics will be a crucial factor in medical practices in the near future. Therefore, the focus of this article will be on recent …


Quality Of Life Of Pregnant Women Who Decide To Terminate Their Pregnancy, N Rattanaprasop, C. Nimnuan Jan 2011

Quality Of Life Of Pregnant Women Who Decide To Terminate Their Pregnancy, N Rattanaprasop, C. Nimnuan

Chulalongkorn Medical Journal

Objective : To study the quality of life (QOL) and related factors of pregnant women who decided to terminate their pregnancy. Design : Cross-sectional descriptive study. Setting : A private clinic in Bangkok. Materials and Methods : One hundred and forty-one women who decided to terminate their pregnancy took part. Demographic data were collected using self-complete questionnaire. The WHOQOL- BREF-THAI questionnaire was used to determine QOL. Result : The QOL score of women who terminated pregnancy was quite low in every dimension especially in mental health. Using reference value; about one-fifth had poor QOL-mental health and one-fourth had poor QOL- …


Functional Improvement Of Stroke Patients At Thai Red Cross Rehabilitation Center, N Tantisiriwat, A. Srinkapaibulaya Jan 2011

Functional Improvement Of Stroke Patients At Thai Red Cross Rehabilitation Center, N Tantisiriwat, A. Srinkapaibulaya

Chulalongkorn Medical Journal

Objective : To determine functional outcome as well as correlations between functional status at admission and length of hospital stay (LOHS) of stroke patients who completely attended rehabilitation program at Thai Red Cross Rehabilitation Center from year 2006 to 2008. Method : Reviewed medical record of stroke patients admitted during August 1, 2006 to December 31, 2008. LOHS, location after discharge and functional status as the following; modified Barthel activity of daily living index (BAI), household and community ambulation were obtained. BAI at admission and discharge were compared. The correlations between functional status at admission and LOHS were determined. Result …


Happiness And Related Factors Of Managing Directors In Industrial Plants In Bangkok, J Wattanasup, R. Kalayasiri Jan 2011

Happiness And Related Factors Of Managing Directors In Industrial Plants In Bangkok, J Wattanasup, R. Kalayasiri

Chulalongkorn Medical Journal

Objective : To study levels of happiness and related factors of managing directors in industrial plants in Bangkok. Participants : Four hundred and thirty-one subjects from industrial plants in Bangkok. Methods : Levels of happiness were obtained by using the Thai Mental Health Indicators-66 (TMHI-66). Demographic, work, and social data were also collected. Managing directors with different levels of happiness were compared with respect to their demographic, work, and social variables by using chi-square tests. Then, the variables that were statistically significantly associated with the level of happiness in the initial analysis were analyzed by using multiple logistic regression analysis. …


Pupil Sizes Of Bodies With Variant Post-Mortem Intervals, P Sinpajakpon, K. Vongpaisarnsin Jan 2011

Pupil Sizes Of Bodies With Variant Post-Mortem Intervals, P Sinpajakpon, K. Vongpaisarnsin

Chulalongkorn Medical Journal

Objective : To determine the relationship between the pupil sizes and the post- mortem intervals in order to estimate the time of death. Setting : Chulalongkorn Forensics Center, Faculty of Medicine, Chulalongkorn University Research design : Prospective descriptive study Materials and Methods : The pupil sizes of the bodies are measured by using pupil gauge with 2, 3, 4, 5, 6, 7, 8 and 9 millimeters scale. Results : Pupils of 171 bodies (141 males and 30 females) with age ranging from 20 to 70 years old are measured by using pupil gauge in particular post-mortem intervals. The average pupil …


Drugs And Promotions: Basic Arguments On Their Controversial Areas, V. Vatjanapukka Jan 2011

Drugs And Promotions: Basic Arguments On Their Controversial Areas, V. Vatjanapukka

Chulalongkorn Medical Journal

“Drugs” are essential for human life. Pharmaceutical companies must have a higher responsibility than other businesses because drugs directly affect lives and health of the consumers. Sometimes, their unwanted impacts cannot be compensated or resolved. Therefore, the pharmaceutical industry should adopt a different framework of thought from other types of marketing. When drug companies run their promotions or lunch any advertising program, doctors and consumers have to be aware of their risks and benefits of the marketing strategies. This paper tries to identify the possible risks and potential benefits of Direct-toConsumer Advertising (DTCA) that may arise. It will allow consumers …


Effects Of Aquatic Exercise On Pulmonary Functionin Healthy Thai Subjects, T Janyacharoen, J Chaichanawongsa, S Namsiri, Y Thongduang, P. Arayawichanond Jan 2011

Effects Of Aquatic Exercise On Pulmonary Functionin Healthy Thai Subjects, T Janyacharoen, J Chaichanawongsa, S Namsiri, Y Thongduang, P. Arayawichanond

Chulalongkorn Medical Journal

Background : Aquatic exercise is an important exercise for people who want to be strong. The warmth and pressure of the water may further assist pain relief, swelling reduction, and ease the physical movement. However, in Thailand no researcher has studied the effects of aquatic exercise on pulmonary function. Objective : This study is aimed to compare the forced vital capacity (FVC) and forced expiratory in one second (FEV1) before (week 0), and immediately after the completion of the aquatic exercise program (week 6) in healthy Thai subjects. Setting : The Faculty of Associated Medical Sciences, Khon Kaen University. Design …


Canine Heartworm (Dirofilaria Immitis, Leidy) And Risk Of Infection In Human, S. Tiawsirisup Nov 2010

Canine Heartworm (Dirofilaria Immitis, Leidy) And Risk Of Infection In Human, S. Tiawsirisup

Chulalongkorn Medical Journal

Canine heartworm (Dirofilaria immitis) is a filarial nematode which dogs, cats and some wildlife creatures are definitive hosts, and humans are accidental hosts. Life cycle of this nematode involves the development in the mosquito vector. Microfilaria released from a female nematode can be found in the definitive host's blood circulation and is required to develop into the third or infective stage larva in the mosquito. Infective stage larva will be released from infected mosquito's mouthpart into the host's skin during the course of taking the blood meal, develop into an adult stage in the definitive host, and reside in the …


ย่อวารสาร, อลิสา จันทร์ปี, สุรางค์ นุชประยูร Nov 2010

ย่อวารสาร, อลิสา จันทร์ปี, สุรางค์ นุชประยูร

Chulalongkorn Medical Journal

No abstract provided.


ดรรชนีผู้แต่งจุฬาลงกรณ์เวชสาร 2010, N/A Nov 2010

ดรรชนีผู้แต่งจุฬาลงกรณ์เวชสาร 2010, N/A

Chulalongkorn Medical Journal

No abstract provided.


ดรรชนีบทความจุฬาลงกรณ์เวชสาร 201, N/A Nov 2010

ดรรชนีบทความจุฬาลงกรณ์เวชสาร 201, N/A

Chulalongkorn Medical Journal

No abstract provided.


Boeck And Drbohlav Locke Egg Serum Medium For Detection Of Blastocystis Hominis, W Saksirisampant, S Nuchprayoon, P Pradniwat, D. Lamchuan Nov 2010

Boeck And Drbohlav Locke Egg Serum Medium For Detection Of Blastocystis Hominis, W Saksirisampant, S Nuchprayoon, P Pradniwat, D. Lamchuan

Chulalongkorn Medical Journal

Objective : To study Blastocystis hominis infection, positivity by using Boeck and Drbohlav Locke egg serum medium (LE) cultivation and Jones' medium. Design : Cross-sectional study. Setting : Bann Kew Savag Mai, Mae Chame District, Chiang Mai Province and Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Materials : One hundred and fifty-eight stool specimens from hill-tribe children, aged 1-18 years old. Methods : All 158 stool specimens were cultivated in Jones' and LE media, transported to the laboratory and examined for B.hominis under the microscope. The parasites were detected after a 72 hr incubation at 37C. Each …


Wolbachia Isolation By Fractioned Centrifugation From Dirofilaria Immitis For Protein Analysis, V Sanprasert, S Sungpradit, S. Nuchprayoon Nov 2010

Wolbachia Isolation By Fractioned Centrifugation From Dirofilaria Immitis For Protein Analysis, V Sanprasert, S Sungpradit, S. Nuchprayoon

Chulalongkorn Medical Journal

Objective : The biological roles of Wolbachia, a filarial intracellular bacteria, have promoted applied researches in lymphatic filariasis. Analysis of Wolbachia proteins will provide complementary information on the biology of Wolbachia, as well as the immune mechanisms against filarial nematodes. We therefore developed a Wolbachia isolation method from Dirofilaria immitis (dog heartworm) for protein analysis. Methods : Wolbachia bacteria were homogenized and isolated by fractioned centrifugation by using 0.85% NaCl supplemented with varying concentration of Nonidet P-40 (NP-40) as the homogenization buffer. The purity of Wolbachia extracts were analyzed by sodium dodecyl sulfate polyacrylamide-gel electrophoresis (SDS-PAGE), and by quantitative polymerase …


Cost-Effectiveness Analysis Of Alkaline Lysis, Magna Pure, And Phenol-Chloroform Dna Extraction Methods Followed By Measurement Of Single Gene Copy Number Using Quantitative Real-Time Pcr For Dirofilaria Immitis Microfilaria, S Sungpradit, S Nuchprayoon, T. Chatsuwan Nov 2010

Cost-Effectiveness Analysis Of Alkaline Lysis, Magna Pure, And Phenol-Chloroform Dna Extraction Methods Followed By Measurement Of Single Gene Copy Number Using Quantitative Real-Time Pcr For Dirofilaria Immitis Microfilaria, S Sungpradit, S Nuchprayoon, T. Chatsuwan

Chulalongkorn Medical Journal

Objective : Dirofilariasis or heartworm disease, a mosquito-borne parasitic disease, continues to be a serious problem in canine (dogs) and feline (cats) species. The disease is caused mainly by the filarial nematode, Dirofilaria immitis. In canine dirofilariasis, the adult worms, present in the pulmonary arteries and the right ventricle, causing damages and leading to pulmonary hypertension and right-sided congestive heart failure. In addition, acute death in feline dirofilariasis causes lung injury resulting in respiratory distress. Being critical to transmission and complex disease pathology, the microfilarial stage is useful in laboratory diagnosis; however, the microfilaria identification process is laborious, difficult and …


Ct Findings Of Pancreatic Ductal Adenocarcinoma At King Chulalongkorn Memorial Hospital: A Study Of 40 Cases With Histological Verification, E Swangjitmetta, L Vajragupta, N Wisedopas, N. Tanpowpong Nov 2010

Ct Findings Of Pancreatic Ductal Adenocarcinoma At King Chulalongkorn Memorial Hospital: A Study Of 40 Cases With Histological Verification, E Swangjitmetta, L Vajragupta, N Wisedopas, N. Tanpowpong

Chulalongkorn Medical Journal

Background : The incidence of pancreatic cancer has been increasing. CT scan is effective and standard modality for imaging of pancreatic cancer. Objective : To describe CT findings in pancreatic ductal adenocarcinoma at King Chulalongkorn Memorial Hospital and to subgroup analyze the enhancement patterns and presence of metastasis of each histological grading. Setting : Department of Radiology and Department of Pathology, Faculty of Medicine, Chulalongkorn University Design : Retrospective descriptive study Materials and Methods : Preoperative dual phase abdominal CT scans and pathological reports of 40 patients with pancreatic adenocarcinoma in King Chulalongkorn Memorial Hospital from 2003 to 2008 were …


Active Management Of The Third Stage Of Labor (Amtsl) Without Controlled Cord Traction At Nongkai Hospital, S. Densiriaksorn Nov 2010

Active Management Of The Third Stage Of Labor (Amtsl) Without Controlled Cord Traction At Nongkai Hospital, S. Densiriaksorn

Chulalongkorn Medical Journal

Objective : To compare simplified active management of the third stage of labor (AMTSL) package with the full AMTSL package in the active management of the third stage of labor with respect to the amount of bleeding. Design : Randomized controlled trial. Setting : Nongkai Hospital. Materials and Methods : Two hundred women with imminent vaginal delivery were randomized into two groups, namely: the study and control groups in the study group, simplified package of the third-stagelabor management [oxytocin injection, cord clamping, uterine message, without controlled cord traction (CCT)] were performed. In the control group, full package of the third-stage-management …