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Chulalongkorn Medical Journal

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Articles 331 - 360 of 4154

Full-Text Articles in Medicine and Health Sciences

Bipolarity Among Pregnant Women At King Chulalongkorn Memorial Hospital And Relationship With Depression Score During Pregnancy And Postpartum Periods, Ratsamimarn Siripalanon, Chutima Roomruangwong Jan 2020

Bipolarity Among Pregnant Women At King Chulalongkorn Memorial Hospital And Relationship With Depression Score During Pregnancy And Postpartum Periods, Ratsamimarn Siripalanon, Chutima Roomruangwong

Chulalongkorn Medical Journal

No abstract provided.


Incidences And Characteristics Of Monkey-Related Injuries Among Locals And Tourists In Mueng District, Lopburi Province, 2013 - 2017, Anothai Juttuporn, Sarunya Hengpraprom, Thanapoom Rattananupong Jan 2020

Incidences And Characteristics Of Monkey-Related Injuries Among Locals And Tourists In Mueng District, Lopburi Province, 2013 - 2017, Anothai Juttuporn, Sarunya Hengpraprom, Thanapoom Rattananupong

Chulalongkorn Medical Journal

No abstract provided.


Personality Change And Associated Factors In Patients With Mild Cognitive Impairment, Chawin Promchaiwattana, Daruj Aniwattanapong Jan 2020

Personality Change And Associated Factors In Patients With Mild Cognitive Impairment, Chawin Promchaiwattana, Daruj Aniwattanapong

Chulalongkorn Medical Journal

No abstract provided.


Volumetric Kinetic Assessment In Dynamic Contrast Enhanced-Mri (Dce-Mri) Of Breast Cancer: A New Method For Evaluation Of Whole Tumor Enhancing Pattern, Jatuporn Chayakulkheeree, Krittika Tongin, Darunee Boonjunwetwat Jan 2020

Volumetric Kinetic Assessment In Dynamic Contrast Enhanced-Mri (Dce-Mri) Of Breast Cancer: A New Method For Evaluation Of Whole Tumor Enhancing Pattern, Jatuporn Chayakulkheeree, Krittika Tongin, Darunee Boonjunwetwat

Chulalongkorn Medical Journal

No abstract provided.


Accuracy Of Ultrasound-Guided Vacuum-Assisted Fineneedle Aspiration For Diagnosis And Management Of Bi-Rads 4 Lesion, Somchanin Pipatpajong, Panida Wongsansuk Jan 2020

Accuracy Of Ultrasound-Guided Vacuum-Assisted Fineneedle Aspiration For Diagnosis And Management Of Bi-Rads 4 Lesion, Somchanin Pipatpajong, Panida Wongsansuk

Chulalongkorn Medical Journal

No abstract provided.


Effect Of Board Games To Enhance Visuospatial Working Memory In Preschool Children In Foundation For Children, Thawanrat Sriwilas, Manika Wisessathorn Jan 2020

Effect Of Board Games To Enhance Visuospatial Working Memory In Preschool Children In Foundation For Children, Thawanrat Sriwilas, Manika Wisessathorn

Chulalongkorn Medical Journal

No abstract provided.


Effects Of A Self-Efficacy Enhancement Program On Recurrence Prevention Behaviors Among Patients With Urolithiasis, Kanokporn Trongmatee, Rapin Polsook Jan 2020

Effects Of A Self-Efficacy Enhancement Program On Recurrence Prevention Behaviors Among Patients With Urolithiasis, Kanokporn Trongmatee, Rapin Polsook

Chulalongkorn Medical Journal

No abstract provided.


Primary Biliary Cholangitis In Thai Woman: A Case Report, Likhasit Sanglutong, Somchai Insiripong Jan 2020

Primary Biliary Cholangitis In Thai Woman: A Case Report, Likhasit Sanglutong, Somchai Insiripong

Chulalongkorn Medical Journal

No abstract provided.


Workplace Violence In Convenience Stores, Piyapat Pandee, Wiroj Jiamjarasrangsi Jan 2020

Workplace Violence In Convenience Stores, Piyapat Pandee, Wiroj Jiamjarasrangsi

Chulalongkorn Medical Journal

No abstract provided.


Effects Of Family Members’ Empowerment Program On Family Members’ Food Preparing Behaviors For Elderly Diabetic Patients, Jintana Attaprajong, Yupa Jewpattanakul, Kerada Krainuwut Jan 2020

Effects Of Family Members’ Empowerment Program On Family Members’ Food Preparing Behaviors For Elderly Diabetic Patients, Jintana Attaprajong, Yupa Jewpattanakul, Kerada Krainuwut

Chulalongkorn Medical Journal

No abstract provided.


Multiple Primary Gists: Unusual Presentation As Jejuno-Jejunal Intussusception, Busaba Jiruppabha Oct 2019

Multiple Primary Gists: Unusual Presentation As Jejuno-Jejunal Intussusception, Busaba Jiruppabha

Chulalongkorn Medical Journal

Gastrointestinal stromal tumors (GISTs) are rare, occurring in 10 - 15 per million, and 0.2% of all gastrointestinaltumors, and is generally considered a solitary tumor. This study presented a 57 year-old female with abdominalpain and intermittent vomiting for 6 months. Acute abdomen series did not show any evidence of a small bowelobstruction. Esophagogastroduodenoscopy (EGD) suggested partial small bowel obstruction. A contrast enhancedCT scan (CECT) of the abdomen demonstrated jejuno-jejunal intussusception induced by an intraluminal tumorand another two mesenteric tumors confirmed by histopathology and immunohistochemistry as GISTs. Thepatient had complete resection for treatment. She recovered without complication and remained well. This …


Protective Effect Of Alpha Lipoic Acid Loaded Calcium Citrate Nanoparticles On Oxidative Stress-Induced Cellular Damage In Human Epidermal Keratinocytes, Boonyaras Bukkavesa, Kanidta Sooklert, Amornpun Sereemaspun Oct 2019

Protective Effect Of Alpha Lipoic Acid Loaded Calcium Citrate Nanoparticles On Oxidative Stress-Induced Cellular Damage In Human Epidermal Keratinocytes, Boonyaras Bukkavesa, Kanidta Sooklert, Amornpun Sereemaspun

Chulalongkorn Medical Journal

Background: Prolonged oxidative stress leads to apoptosis of keratinocytes and, consequently, results in skincell damage.Objective: To investigate the in vitro effects of alpha lipoic acid (LA) and lipoic acid loaded calcium citratenanoparticles (LA loaded CaCitNPs) in terms of cell protection against oxidative stress-induced cellular damage.Methods: HaCaT cells were preincubated with and without LA and LA loaded CaCitNPs before oxidative stressinduction by H2O2. The protective effects of both LA and LA loaded CaCitNPs on HaCaT cells were assessedby the percentage of cell viability, percentage of proliferated cells, type of cell death, and ROS generation. Inaddition, we evaluated the effect of LA …


A Glass Marble Ball In The Maxillary Sinus, Transorbital Floor Penetration: A Case Report, Krissanaporn Jirawarakul Oct 2019

A Glass Marble Ball In The Maxillary Sinus, Transorbital Floor Penetration: A Case Report, Krissanaporn Jirawarakul

Chulalongkorn Medical Journal

Foreign bodies in the sinus are uncommon and transorbital foreign bodies in the maxillary sinus are veryrare. We hereby described a case of a glass marble ball about 1.6 cm in diameter that penetrated into the rightmaxillary sinus through the orbital floor without globe rupture. The foreign body in the sinus should be removedto prevent further infection and other complications. In this case, the glass marble ball was removed by a transnasalendoscopic technique with a widened maxillary antrum after guarding of orbital ball upward in order to preventthe orbital injury. There were no immediate and long term postoperative complications.


The 105th Anniversary Of King Chulalongkorn Memorial Hospital: Proud Of Our Past, Preparing For Our Future, Sittisak Honsawek Oct 2019

The 105th Anniversary Of King Chulalongkorn Memorial Hospital: Proud Of Our Past, Preparing For Our Future, Sittisak Honsawek

Chulalongkorn Medical Journal

No abstract provided.


Evaluation Of T2 Value For Detection Of Metastatic Cervical Lymph Node In Head And Neck Squamous Cell Carcinoma Compared With 18f-Fdg Pet/Ct, Netsiri Dumrongpisutikul, Vorada Sonthithavorn Oct 2019

Evaluation Of T2 Value For Detection Of Metastatic Cervical Lymph Node In Head And Neck Squamous Cell Carcinoma Compared With 18f-Fdg Pet/Ct, Netsiri Dumrongpisutikul, Vorada Sonthithavorn

Chulalongkorn Medical Journal

Background: Difference in the staging of head and neck cancer leads to different treatments and managementsof the patients to minimize mortality and improve long-term health and social consequences.Objective: This study aimed to utilize the T2 signal value on T2WI for early detection of metastatic lymph nodes.Methods: We retrospectively reviewed 18-fluoro-deoxyglucose positron emission tomography/computedtomography (18F-FDG PET/CT) and magnetic resonance imaging (MRI) results of patients with head and necksquamous cell carcinomas, from January 2012 to February 2018. The ratio between the T2 signal values of thelymph nodes and sternocleidomastoid muscles were calculated for each lymph node. Analytical comparisonsbetween T2 signal value ratios …


Impact Of Shift Work On Sleep Quality Among Nursing Staff, Patthrarawalai Sirinara, Nitt Hanprathet, Krit Pongpirul, Wiroj Jiamjarasrangsi Oct 2019

Impact Of Shift Work On Sleep Quality Among Nursing Staff, Patthrarawalai Sirinara, Nitt Hanprathet, Krit Pongpirul, Wiroj Jiamjarasrangsi

Chulalongkorn Medical Journal

Background: Shift work is common among nurses because health care is the industry that covers 24 hoursa day, 7 days a week. How a healthcare organization alters staffing patterns to reduce fatigue among nursing staffis challenging. This study aimed to understand whether poor sleep quality persisted in nursing staff who didshift work and whether there were any specific risk factors for poor sleep quality among nursing staff. The studyused a validated tool called the Pittsburgh Sleep Quality Index (PSQI) in Thai version for sleep quality assessment.Methods: This study was a cross-sectional study. Semi-structured questionnaires were used to interviewnursing staff who …


Exercise Training Improves Age-Related Changes In Cerebral Capillary Vascularity Through The Upregulation Of Pi3k / Akt Signaling, Channipa Chanpakdee, Sheepsumon Viboolvorakul, Suthiluk Patumraj Oct 2019

Exercise Training Improves Age-Related Changes In Cerebral Capillary Vascularity Through The Upregulation Of Pi3k / Akt Signaling, Channipa Chanpakdee, Sheepsumon Viboolvorakul, Suthiluk Patumraj

Chulalongkorn Medical Journal

Background: Currently, the number of the elderly has been rising sharply worldwide. Seemingly, age-inducedcerebral endothelial dysfunction may lead to vascular abnormality that can later progress to cerebrovascularand neurodegenerative diseases. Moreover, several evidences have shown that age-related oxidative stress anddecline in cellular function appeared in the vascular system both in humans and laboratory animals. The role ofexercise training in the regulation of age-related oxidative stress and endothelial functions have been reported.Objectives: To investigate whether exercise training can prevent age-induced cerebral endothelial dysfunctionassociated to PI3K/Akt signaling.Methods: Male Wistar rats were randomly divided into 3 groups: sedentary-young group (SE-Young, 4 months),sedentary-aged group (SE-Aged, …


Association Of Vitamin D-Related Genetic Variations And The Susceptibility Among Thai Children With Biliary Atresia, Kanjaporn Sirisomboonlarp, Natthaya Chuaypen, Sittisak Honsawek, Palittiya Sintusek, Voranush Chongsrisawat, Pisit Tangkijvanich Oct 2019

Association Of Vitamin D-Related Genetic Variations And The Susceptibility Among Thai Children With Biliary Atresia, Kanjaporn Sirisomboonlarp, Natthaya Chuaypen, Sittisak Honsawek, Palittiya Sintusek, Voranush Chongsrisawat, Pisit Tangkijvanich

Chulalongkorn Medical Journal

Background: Vitamin D deficiency is commonly found in children with biliary atresia (BA). Single nucleotidepolymorphisms (SNPs) in vitamin D-related genes are linked to circulating vitamin D levels in various chronicliver diseases.Objective: This study aimed to investigate whether vitamin D related SNPs were associated with diseasesusceptibility and clinical manifestations in Thai children with BA.Methods: DNA specimens from 85 Thai children with BA and 90 age and gender matched healthy controlswere genotyped for DHCR7 rs12800438, CYP2R1 rs10741657 and GC rs7041 using TaqMan polymerase chainreactions.Results: The frequency of the T allele of GC rs7041 was significantly higher in children with BA compared withhealthy …


Lung Function And Exercise Performance Assessment After Inhalation Of Naturally Essential Oils: A Descriptive Observational Study, Hamzeh Al Zabadi, Azmi Hussein, Jamal Shaker, Belal Rahhal, Nidal Amin Jaradat, Malik Al Qub Oct 2019

Lung Function And Exercise Performance Assessment After Inhalation Of Naturally Essential Oils: A Descriptive Observational Study, Hamzeh Al Zabadi, Azmi Hussein, Jamal Shaker, Belal Rahhal, Nidal Amin Jaradat, Malik Al Qub

Chulalongkorn Medical Journal

Background: Essential oils have gained massive attention. We aimed to assess the effects of inhalation ofClinopodium serpyllifolium and Cymbopogon citratus volatile oils on exercise performance and lung function.Methods: Twenty physical education students were randomly assigned into two groups: Clinopodiumserpyllifolium and Cymbopogon citratus (10 participants each). One group was nebulized with Clinopodiumserpyllifolium oil and the other by Cymbopogon citratus oil at a concentration of (0.02 ml/kg of body mass)which was mixed with 2 ml of normal saline before 800 m running tests. Lung function tests were measured usinga spirometer pre and post nebulization.Results: There was a significant increase in Forced Expiratory …


An Exploratory Factor Analysis Of Post-Concussion Syndromes In Thai People After Head Injury: A Psychometric Properties Study, Chanokporn Jitpanya, Kanjana Kinklaykan, Tanita Puengching Oct 2019

An Exploratory Factor Analysis Of Post-Concussion Syndromes In Thai People After Head Injury: A Psychometric Properties Study, Chanokporn Jitpanya, Kanjana Kinklaykan, Tanita Puengching

Chulalongkorn Medical Journal

Background: Thousands of patients suffer a head injury in Thailand. Some might recover completely but manyare still at risk of having post-concussion syndromes (PCS) for months or years after injury. PCS has a poordiagnosis. The Rivermead Post-Concussion Symptoms Questionnaire (RPQ) is one of the instruments usedfor evaluating PCS.Objectives: This study aimed to analyze the factors of PCS, and to validate the psychometric properties of RPQin Thai people after a head injury.Method: In a secondary analysis of data drawn from two original studies, 253 head injury patients who visitedNeurosurgical Clinics of King Bhumibol Adulyadej Hospital, and the Police General Hospital, Thailand …


Indoor Air Microbial Counts In Dormitory Of Nursing Students, Bangkok, Pipat Luksamijarulkul, Maneenut Wutthikarn, Poolsuk Janepanish Visudtibhan, Pisit Vatanasomboon Oct 2019

Indoor Air Microbial Counts In Dormitory Of Nursing Students, Bangkok, Pipat Luksamijarulkul, Maneenut Wutthikarn, Poolsuk Janepanish Visudtibhan, Pisit Vatanasomboon

Chulalongkorn Medical Journal

Background: Most medical and nursing students live in institute dormitories located in a university hospitalwhere a variety of biological and chemical hazards are used and probably diffuse into the dormitory environments.Objectives: This study aimed to investigate bacterial and fungal counts, and microbial groups in a dormitory ofnursing students in Bangkok, Thailand.Methods: Two-time assessments of bacterial and fungal counts in indoor air samples collected from a dormitoryof nursing students including 8 floors with 95 rooms were carried out. A total of 380 indoor air samples (190 forbacteria and 190 for fungi) were collected from all dormitory rooms using a BioStage Impactor …


Depression In Patients With Type 2 Diabetes Attending At Chao Phya Abhaibhubejhr Hospital, Amporn Nueangjaknak, Siriluck Suppapitiporn Jul 2019

Depression In Patients With Type 2 Diabetes Attending At Chao Phya Abhaibhubejhr Hospital, Amporn Nueangjaknak, Siriluck Suppapitiporn

Chulalongkorn Medical Journal

Background: Diabetes mellitus (DM) is one of the most common public health problems worldwide. It is achronic, debilitating disease that needs lifelong care for both physical and psychological aspects. Previousstudies on depression in diabetic patients are scant in Thailand.Objective: To determine the prevalence of depression and its associated factors in patients with type 2 diabetes at Chao Phya Abhaibhubejhr Hospital, Prachinburi Province.Methods: A cross-sectional descriptive study was conducted among patients with type 2 diabetes at the Outpatient Clinic of Chao Phya Abhaibhubejhr Hospital, Prachinburi Province, Thailand from August to December 2017. The instruments were demographic and clinical characteristics questionnaires, the …


Comparison Of Lower Extremity Range Of Motion During Walking Between Children With Cerebral Palsy And Normal Children, Parinnapak Mahasup, Siriluck Kanchanomai Jul 2019

Comparison Of Lower Extremity Range Of Motion During Walking Between Children With Cerebral Palsy And Normal Children, Parinnapak Mahasup, Siriluck Kanchanomai

Chulalongkorn Medical Journal

Background: Walking is very important for children with cerebral palsy but they lack voluntary coordination ofmuscle movements. Moreover, affected children have their own pattern of walking which is different from normal walking. Thus, gait analysis is a great tool for diagnosis with the aim to rehabilitate the children as best as possible.Objective: To compare lower extremity range of motion during walking between children with cerebral palsy and normal children.Methods: The participants were 15 children with cerebral palsy (5 - 15 years of age). Their motor abilities wereclassified at level 1 - 3 on the Gross Motor Function Classification System. The …


Effects Of General Obesity On Heart Rate Variability In Thai People With Physical Inactivity, Jantakan Saechee, Kanita Wannasamai, Pattharaporn Jaimanee, Decha Pinkeaw, Kroekkiat Chinda, Tharnwimol Inthachai Jul 2019

Effects Of General Obesity On Heart Rate Variability In Thai People With Physical Inactivity, Jantakan Saechee, Kanita Wannasamai, Pattharaporn Jaimanee, Decha Pinkeaw, Kroekkiat Chinda, Tharnwimol Inthachai

Chulalongkorn Medical Journal

Background: Obesity is an important risk factor of cardiovascular diseases. Heart rate variability (HRV), andmaximum oxygen consumption (VO2max) are parameters of cardiorespiratory function for determining aerobic capacity. However, the studies that investigated the effects of obesity on HRV, pulmonary function and VO2 max in male participants aged 40 and 50 years, have been limited.Objectives: This study aimed to compare HRV, pulmonary function and VO2max in male participants with normal body mass index (BMI) (18.5 – 22.9 kg/m2, n = 10), and Class I obesity (25 - 29.9 kg/m2, n = 10) and also to use HRV to assess cardiopulmonary function …


Cytotoxicity And Apoptotic Mechanisms Of Different Solvent Extracts From Ipomoea Pes-Caprae On Human Nasopharyngeal Cells, Chantarawan Saengkhae, Napaporn Uawongyart, Sunantha Osiri Jul 2019

Cytotoxicity And Apoptotic Mechanisms Of Different Solvent Extracts From Ipomoea Pes-Caprae On Human Nasopharyngeal Cells, Chantarawan Saengkhae, Napaporn Uawongyart, Sunantha Osiri

Chulalongkorn Medical Journal

Background: Ipomoea pes-caprae serves as a valuable medicinal plant with pharmacological activities including antioxidant, analgesic, anti-inflammatory, antispasmodic, and anticancer activities. Although some scientific literatures have demonstrated its anticancer activities, the exact mechanism has not been fully elucidated.Objectives: To study the cytotoxicity and apoptotic mechanisms of different solvent extracts from Ipomoeapes-caprae on human nasopharyngeal (KB) cells.Methods: The dried plant was macerated in hexane (Hex) or ethanol: water (EtOH). The supercritical fluidextraction process used carbon dioxide (SCO2) as the extracting solvent. Cytotoxic activity was determined byMTT assay. The apoptotic mechanism and its effect on mitochondrial membrane potential was measured byDNA agarose gel …


Characteristics And Physical Outcomes Of Kratom Users At A Substance Abuse Treatment Center, Somreudee Eaimchaloay, Rasmon Kalayasiri, Sujira Prechawit Jul 2019

Characteristics And Physical Outcomes Of Kratom Users At A Substance Abuse Treatment Center, Somreudee Eaimchaloay, Rasmon Kalayasiri, Sujira Prechawit

Chulalongkorn Medical Journal

Background: Despite many disadvantages such as physical and mental disorders, family disruption, crime, etc., substance use disorder is continuously reported worldwide. Twenty - nine million people were reported to suffer from substance abuse. In addition, the survey found that only 1/6 of substance abusers throughout the world were able to access medical services. Kratom (Mitragyna speciosa Korth) has been used not only as medicine, but also as psychedelic drug for a long time.Objective: To study behavioral and physical consequences of kratom use.Methods: One hundred and six kratom users were recruited into this study at the Princess Mother NationalInstitute on Drug …


Prevalence Of Hypertension And Associated Factors Among Healthcare Workers: A Cross-Sectional Study, Patthrarawalai Sirinara, Nitt Hanprathet, Wiroj Jiamjarasrangsi Jul 2019

Prevalence Of Hypertension And Associated Factors Among Healthcare Workers: A Cross-Sectional Study, Patthrarawalai Sirinara, Nitt Hanprathet, Wiroj Jiamjarasrangsi

Chulalongkorn Medical Journal

Background: Hypertension is an important public health challenge in Thailand. Whether shift work and typesof working patterns in healthcare workers is linked to increased risk of high blood pressure remains controversial. The aim of this study was to quantify the prevalence of hypertension and to determine the effect of shift work and working patterns in healthcare workers of a large tertiary, university-based hospital in Bangkok, Thailand.Methods: A cross-sectional study was conducted using the annual health examination results and occupational health questionnaires of 6,014 healthcare workers at a large tertiary, university-based hospital. Sleep quality was measured using the Pittsburgh Sleep Quality …


Ecmo Support After Arterial Switch Operation: A Case Report Series From A Single Institution, Kanyarad Boonthim, Jule Namchaisiri, Vichai Benjacholamas Jul 2019

Ecmo Support After Arterial Switch Operation: A Case Report Series From A Single Institution, Kanyarad Boonthim, Jule Namchaisiri, Vichai Benjacholamas

Chulalongkorn Medical Journal

Extracorporeal membrane oxygenators (ECMO) after arterial switch operation (ASO) is a rescue therapy forpatients who cannot wean from cardiopulmonary bypass as a bridge to recovery and/or transplantation. We,hereby, present a case report series of four patients from an institute who underwent ECMO after ASO fordextro-transposition of the great arteries (d-TGA). Two patients subsequently weaned off ECMO but only onepatient survived to discharge. ASO is a complex surgery that requires an approach of a multi-disciplinary teamwhere ECMO is a useful adjunct for recovery in difficult cases. Nevertheless, ECMO after ASO involvesdiscriminating patient selection, prompt timing to initiate and good care team …


Marking The 102nd Anniversary Of Chulalongkorn University, Sittisak Honsawek Jul 2019

Marking The 102nd Anniversary Of Chulalongkorn University, Sittisak Honsawek

Chulalongkorn Medical Journal

Chulalongkorn University, as the country’s first university, continues to uphold the royal intent of HMKing Chulalongkorn (RAMA V) and HM King Vajiravudh (RAMA VI) to be the “cornerstone of the capital city,” while aspiring towards sustainably becoming a world-class university. The university was originally founded during King Chulalongkorn’s reign as a school for training royal pages and civil servants in 1899 (B.E. 2442) at the Grand Palace of Thailand. It was later established as a national university in 1917, making it the oldest institute of higher education in Thailand. During the reign of Chulalongkorn’s son, King Vajiravudh, the Royal Pages …


Correlation Between Trans Rectal Ultrasound Guided Prostate Biopsy And Radical Prostatectomy Specimen And Risk Factors For Upgraded Gleason Score In Prostate Cancer, Aekgarin Palakho, Apirak Santi-Ngamkun, Julin Opanuraks, Kavirach Tantiwongse, Supoj Ratchanon, Kamol Panumatrassamee Jul 2019

Correlation Between Trans Rectal Ultrasound Guided Prostate Biopsy And Radical Prostatectomy Specimen And Risk Factors For Upgraded Gleason Score In Prostate Cancer, Aekgarin Palakho, Apirak Santi-Ngamkun, Julin Opanuraks, Kavirach Tantiwongse, Supoj Ratchanon, Kamol Panumatrassamee

Chulalongkorn Medical Journal

Background: Gleason score is an important pathologic factor for risk stratification in prostate cancer. Upgraded Gleason score is not uncommon after radical prostatectomyObjectives: This study aimed to investigate the prevalence of upgraded Gleason scores between trans rectalultrasound guided prostate biopsy (TRUS-biopsy) and radical prostatectomy (RP) specimen and to determinethe predictive factors for increased Gleason scores.Methods: We retrospectively reviewed the medical records of prostate cancer patients who underwent RP from June 2006 – June 2016 at King Chulalongkorn Memorial Hospital (KCMH). Gleason scores from TRUS-biopsy and RP were compared. Pre-operative clinical parameters were analyzed to determine the risk factors of upgraded …