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Articles 6751 - 6780 of 8080
Full-Text Articles in Medicine and Health Sciences
Pneumopericardium Associated With A Steady Cough, Ahmet Özyazicioğlu, Ahmet Yavuz Balci
Pneumopericardium Associated With A Steady Cough, Ahmet Özyazicioğlu, Ahmet Yavuz Balci
Turkish Journal of Medical Sciences
YAZICIOĞLU Ahmet Yavuz BALCI Department of Cardiovascular Surgery, Faculty of Medicine, Atatürk University, Erzurum, Turkey
Analyses Of Surface Dose From High Energy Photon Beams For Different Clinical Setup Parameters, Nadi̇r Küçük, Ayhan Kiliç, Gönül Kemi̇kler, Lütfi̇ Özkan, Kayihan Engi̇n
Analyses Of Surface Dose From High Energy Photon Beams For Different Clinical Setup Parameters, Nadi̇r Küçük, Ayhan Kiliç, Gönül Kemi̇kler, Lütfi̇ Özkan, Kayihan Engi̇n
Turkish Journal of Medical Sciences
Surface and build-up region doses of 6, 15 and 25 MV photon beams were investigated for several clinical setup parameters. Evaluated setups included open fields, physical wedge (PW) fields, virtual wedge (VW) fields and blocked fields. The effects of field size, acrylic block tray, source-to-surface distance (SSD) and off-axis distance on surface dose were determined for each of these setups. Siemens Mevatron MD2 (6-15 MV) and Mevatron-KD2 (6-25 MV) linear accelerators were used to measure both the surface and build-up region doses. The surface dose increased as field size increased in open fields. There was no significant difference between 6 …
Radioimmune Imaging Of Diabetic Foot Infection -Tc-99m-Labelled Antigranulocyte Antibody In Combination With Tc-99m-Methylene Diphosphonate Bone Scintigraphy, Hripsime Artjun Bohchelian, Anelia Dimitrova Klisarova, Lidia Asenova Koeva
Radioimmune Imaging Of Diabetic Foot Infection -Tc-99m-Labelled Antigranulocyte Antibody In Combination With Tc-99m-Methylene Diphosphonate Bone Scintigraphy, Hripsime Artjun Bohchelian, Anelia Dimitrova Klisarova, Lidia Asenova Koeva
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the clinical efficacy of immunoscintigraphy with Tc-99m-labelled antigranulocyte antibody in combination with Tc-99m-methylene-diphosphonate (MDP) bone scanning in diabetic foot infection. The study group comprised 42 Type 2 diabetics with foot infection. Pre- and postprandial blood glucose level, HbA1c, urinary glucose, microalbuminuria, total cholesterol, LDL-cholesterol, HDL-cholesterol, and bacteriological cultures were analyzed. Investigation of transcutaneous oxygen tension, vibration sensation, electromyo-graphy, and Doppler ankle/brachial systolic blood pressure index was carried out. Radiographs centered on the feet were performed. All patients underwent bone scintigraphy with 370 MBq Tc-99m-MDP three hours after injection in 3 projections. Radioimmune …
Detection Of Human Cytomegalovirus Gene In Formalin-Fixed Paraffin-Embedded Fetal Tissues, Si̇bel Gündeş, Richard Mo, Nomi Konomi, Jaucheng Tzeng, Rhoda Sperling, Xiaoping Li, David Zhang
Detection Of Human Cytomegalovirus Gene In Formalin-Fixed Paraffin-Embedded Fetal Tissues, Si̇bel Gündeş, Richard Mo, Nomi Konomi, Jaucheng Tzeng, Rhoda Sperling, Xiaoping Li, David Zhang
Turkish Journal of Medical Sciences
NDEŞ^1 Richard MO^1 Nomi KONOMI^1 Jaucheng TZENG^2 Rhoda SPERLING^3 Xiaoping LI^2 David ZHANG^2 Departments of Microbiology^1, Pathology^2, Obstetrics and Gynecology^3, Mount Sinai School of Medicine, New York, New York 10021
In Vitro Esterase Activity Of Carbonic Anhydrase On Total Esterase Activity Level In Serum, Muhammet Fevzi̇ Polat, Barbaros Nalbantoğlu
In Vitro Esterase Activity Of Carbonic Anhydrase On Total Esterase Activity Level In Serum, Muhammet Fevzi̇ Polat, Barbaros Nalbantoğlu
Turkish Journal of Medical Sciences
The in vitro esterase activity of carbonic anhydrase on total esterase activity level was investigated. This effect was obtained by subtracting the value of net esterase from the value of total esterase in sera with normal (95.22 ± 8.87) and high glucose levels (208.58 ± 87.90). Total esterase activity, net esterase activity and esterase activity of carbonic anhydrase were 20.2 ± 1.9, 18.1 ± 1.8 and 2.1 ± 0.7 U/min/mL serum in sera with a normal glucose level, and 21.3 ± 2.8, 17.9 ± 2.9 and 3.4 ± 1.2 U/min/mL serum in sera with a high glucose level, respectively. Thus, …
The Effect Of Simvastatin Treatment On Plasma Ubiquinone, Blood Atp Concentrations, Total Antioxidant Capacity And Muscle Related Markers, Emel Alteki̇n, Banu Önvural, Canan Çoker, Sema Güneri̇, Sezer Çalişkan
The Effect Of Simvastatin Treatment On Plasma Ubiquinone, Blood Atp Concentrations, Total Antioxidant Capacity And Muscle Related Markers, Emel Alteki̇n, Banu Önvural, Canan Çoker, Sema Güneri̇, Sezer Çalişkan
Turkish Journal of Medical Sciences
It has been hypothesized that treating hypercholesterolemic patients with statins will lead not only to a reduction in cholesterol, but also to inhibited synthesis of other compounds that derive from the synthetic pathway of cholesterol. One important by-product is ubiquinone (CQ), which has a pivotal role in mitochondrial electron transport and antioxidant activity. We therefore investigated the effect of 2 months of simvastatin treatment (20 mg/day) on blood ATP concentration, plasma total antioxidant capacity and ubiquinone levels in 17 hypercholesterolemic patients (age range: 40 to 65). To evaluate the possible muscle-related side effects, plasma CK activity and myoglobin concentrations were …
Influence Of Cigarette Smoking On Thyroid Gland Volume: An Ultrasonographic Approach, Fatma Gül Aksoy, Özcan Kesi̇m
Influence Of Cigarette Smoking On Thyroid Gland Volume: An Ultrasonographic Approach, Fatma Gül Aksoy, Özcan Kesi̇m
Turkish Journal of Medical Sciences
The aim of the present prospective study was to investigate the influence of smoking on ultrasonographically determined thyroid gland volume and echo-texture in a large randomly selected group of 500 healthy subjects of both sexes from a non-iodine deficient area. An accurate ultrasonographic technique and the Brunn method were used to determine the thyroid volume of each volunteer. The examiners had no idea of the smoking habits of the volunteers. In 257 non-smokers the mean value of the right thyroid lobe volume and the left thyroid lobe volume were 7.97 ± 5.27 ml and 6,94 ± 4.82 ml respectively, whereas …
A Case Of Mad Honey Poisoning Presenting With Convulsion: Intoxication Instead Of Alternative Therapy, Embi̇ya Di̇lber, Mukaddes Kalyoncu, Ni̇lgün Yariş, Ayşenur Ökten
A Case Of Mad Honey Poisoning Presenting With Convulsion: Intoxication Instead Of Alternative Therapy, Embi̇ya Di̇lber, Mukaddes Kalyoncu, Ni̇lgün Yariş, Ayşenur Ökten
Turkish Journal of Medical Sciences
İLBER Mukaddes KALYONCU Nilgün YARIŞ Ayşenur ÖKTEN Department of Pediatrics, Faculty of Medicine, Karadeniz Technical University, Trabzon - Turkey
The Occurrence Of Retinopathy In 11 Eyes After A Solar Eclipse, 1999, Nuray Akyol, Turgut Yilmaz, Burak Turgut
The Occurrence Of Retinopathy In 11 Eyes After A Solar Eclipse, 1999, Nuray Akyol, Turgut Yilmaz, Burak Turgut
Turkish Journal of Medical Sciences
To present the visual outcome of patients with solar retinopathy and evaluate the effects of treatment on the visual prognosis. One hundred and eighty-eight patients with visual disturbances applied for ophthalmic examination following the solar eclipse on August 11, 1999. All patients underwent routine ophthalmologic examination; those with fundus changes also underwent fundus fluorescein angiography, Amsler grid and computerised perimetry. Among them, nine patients (11 eyes) were evaluated as having solar retinopathy with decreased visual acuity and discernible fundus findings. Mean age was 21.5 (17-34) in this group. Five patients were given treatment, three were on oral methyl prednisolon and …
Enhanced Susceptibility To In Vitro Oxidation Of Apolipoprotein B-Containing Lipoproteins And Antioxidant Status In Patients With Coronary Artery Disease, Zehra Serdar, Emre Sarandöl, Melahat Di̇ri̇can, Akin Serdar, Di̇lek Yeşi̇lbursa, Asuman Tokullugi̇l
Enhanced Susceptibility To In Vitro Oxidation Of Apolipoprotein B-Containing Lipoproteins And Antioxidant Status In Patients With Coronary Artery Disease, Zehra Serdar, Emre Sarandöl, Melahat Di̇ri̇can, Akin Serdar, Di̇lek Yeşi̇lbursa, Asuman Tokullugi̇l
Turkish Journal of Medical Sciences
Lipoprotein oxidation may play a pivotal role in the pathogenesis of atherosclerosis, and vitamin E and b-carotene have been proposed to prevent the development and progression of atherosclerosis. The aim of this study was to investigate the oxidative susceptibility of apolipoprotein B (apo B)-containing lipoproteins and their relation with vitamin E and total carotene levels. The susceptibility of apo B-containing lipoproteins to oxidation, plasma malondialdehyde (MDA), serum vitamin E, total carotene, lipid and lipoprotein levels were studied in 177 patients with coronary artery disease (CAD) and 75 non-CAD subjects. All subjects (n = 252) had undergone coronary catheterization. Student's unpaired …
The Relation Of Cerebrospinal Fluid Nitric Oxide Levels To Prognosis And Differential Diagnosis Of Meningitis, Kasim Çeti̇n, Serpi̇l Erol, Hülya Aksoy, Mehmet Akin Taşyaran
The Relation Of Cerebrospinal Fluid Nitric Oxide Levels To Prognosis And Differential Diagnosis Of Meningitis, Kasim Çeti̇n, Serpi̇l Erol, Hülya Aksoy, Mehmet Akin Taşyaran
Turkish Journal of Medical Sciences
This study was designed to investigate the role of nitric oxide (NO) in the differential diagnosis of bacterial, tuberculous and viral meningitis, and the relation between cerebrospinal fluid (CSF) NO levels and meningitis prognosis. Twenty patients with bacterial meningitis, 9 with tuberculous meningitis, 11 with viral meningitis/meningoencephalitis and 21 control patients were included in the study. CSF NO levels were investigated by measuring the levels of nitrite with a colorimetric test. Mean CSF nitrite levels were 3.9 ± 2.0 µmol/l in bacterial meningitis, 2.7 ± 1.9 µmol/l in tuberculous meningitis, 1.9 ± 1.7 µmol/l in viral meningitis/meningoencephalitis and 1.4 ± …
Oxidative Stress In Mothers And Their Newborns In Different Types Of Labour, İdri̇s Mehmetoğlu Akkuş, Ali̇ Kart, Osman Çağlayan, Meti̇n Çapar, Recep Gökçe
Oxidative Stress In Mothers And Their Newborns In Different Types Of Labour, İdri̇s Mehmetoğlu Akkuş, Ali̇ Kart, Osman Çağlayan, Meti̇n Çapar, Recep Gökçe
Turkish Journal of Medical Sciences
HMETOĞLU (AKKUŞ)^1 Ali KART^1 Osman ÇAĞLAYAN^1 Metin ÇAPAR^2 Recep GÖKÇE^1 Departments of 1Biochemistry, 2Obstetrics and Gynaecology, Faculty of Medicine, Selçuk University. Konya - Turkey
Ifn-G-Mediated Transcriptional Induction Of The Ido (Indolamine 2,3-Dioxygenase) Gene Requires Activity Of P68/Pkr Protein Kinase, Ni̇lüfer Gülmen İmi̇r, Ayşegül Nasircilar, Hakan Akça, Teki̇nalp Gelen, Mehmet Öğüş, Şeyda Karaveli̇, Osman Ni̇dai̇ Özeş
Ifn-G-Mediated Transcriptional Induction Of The Ido (Indolamine 2,3-Dioxygenase) Gene Requires Activity Of P68/Pkr Protein Kinase, Ni̇lüfer Gülmen İmi̇r, Ayşegül Nasircilar, Hakan Akça, Teki̇nalp Gelen, Mehmet Öğüş, Şeyda Karaveli̇, Osman Ni̇dai̇ Özeş
Turkish Journal of Medical Sciences
We investigated whether the activity of double-stranded RNA activated kinase (p68/PKR) is necessary for induction of IDO (indolamine 2,3 -dioxygenase) gene by IFN-\gamma. For this purpose, we planned to abrogate the function of cellular wt-PKR gene. Clones of ME180 cells expressing the dominant negative form of PKR were selected in the presence of neomycin. Then these cells were treated with IFN-\gamma and accumulation of IDO protein was determined by Western blot analysis. We found that clones expressing the dominant negative form of the PKR gene were not only resistant to IFN-\gamma-mediated killing, but were also incapable of inducing accumulation of …
Intraarticular Cyst Of The Knee, Gülay Yeği̇noğlu, Osman Aynaci, Ahmet Uğur Turhan
Intraarticular Cyst Of The Knee, Gülay Yeği̇noğlu, Osman Aynaci, Ahmet Uğur Turhan
Turkish Journal of Medical Sciences
GİNOĞLU^1 Osman AYNACI^2 Ahmet Uğur TURHAN^2 Department of ^1Anatomy, ^2Orthopedic Surgery, School of Medicine, Karadeniz Technical University, 61080 Trabzon - Turkey
Evaluation Of The Prevalence Of Temporomandibular Joint Disorder Syndrome In Dental School Students With Psychometric Analysis, Neci̇p Mutlu, Hasan Herken, Eni̇s Güray, Fati̇h Öz, Abdullah Kalayci
Evaluation Of The Prevalence Of Temporomandibular Joint Disorder Syndrome In Dental School Students With Psychometric Analysis, Neci̇p Mutlu, Hasan Herken, Eni̇s Güray, Fati̇h Öz, Abdullah Kalayci
Turkish Journal of Medical Sciences
Aim: Despite the increasing volume of evidence implicating psychological factors in patients with temporomandibular joint (TMJ) disorder syndrome, these aspects of management are frequently neglected. In the diagnosis and treatment of this syndrome, clinical examination must be accompanied by an evaluation of the patients' emotional condition. In our study, the prevalence of TMJ disorders of dental students and the relation between TMJ disorder syndrome and the emotional condition of the patient were evaluated. Methods: The study group consisted of 156 males and 105 females: a total of 261 students. For the psychometric analysis the Minnesota Multiphasic Personality Inventory (MMPI), Symptom …
Arsenic Trioxide Has Additive Cytotoxic Effects On Mcf-7 Breast Cancer Cell Line With Taxanes, Canfeza Sezgi̇n, Ulus Ali̇ Şanli, Rüçhan Uslu, Erdem Göker
Arsenic Trioxide Has Additive Cytotoxic Effects On Mcf-7 Breast Cancer Cell Line With Taxanes, Canfeza Sezgi̇n, Ulus Ali̇ Şanli, Rüçhan Uslu, Erdem Göker
Turkish Journal of Medical Sciences
Breast cancer is the most prevalent cancer in women and an important cause of both morbidity and mortality. Although long-term disease-free survival is offered to women with early stage disease by current treatment modality, some, 30-40% of patients will have metastatic disease. Treatment of patients with metastatic disease is a great challenge for oncologists. Therefore, new drugs and therapeutic options for women with metastatic breast cancer are urgently required. Arsenical compounds have cytotoxic effects on several cancer cell lines including promyelocytic leukemia, esophageal carcinoma, megakaryocytic leukemia, and malignant lymphocytic cell lines. In addition, recent studies showed that arsenic trioxide (As_2O_3) …
Protective Effect Of Nitric Oxide In Lung Injury Associated With Cerulein-Induced Acute Pancreatitis, Abdulkadi̇r Bedi̇rli̇, Erdoğan M. Sözüer, Recep Saraymen, Nai̇l Ersöz, Eser Kiliç
Protective Effect Of Nitric Oxide In Lung Injury Associated With Cerulein-Induced Acute Pancreatitis, Abdulkadi̇r Bedi̇rli̇, Erdoğan M. Sözüer, Recep Saraymen, Nai̇l Ersöz, Eser Kiliç
Turkish Journal of Medical Sciences
The aim of this study was to investigate the role of NO in the pathogenesis of lung injury associated with pancreatitis, and the relation between malondialdehyde (MDA) and myeloperoxidase (MPO). Forty Wistar male rats were divided into control or pancreatitis groups, and treated with saline, L-arginine (100 mg/kg i.v.), NO donor, or N-nitro-L-arginine methyl ester (L-NAME) (10 mg/kg i.v.), an inhibitor of NO synthase. Pancreatitis was induced in rats intravenously via the administration of cerulein (10 µg/kg/h) for 4 h). Eight hours after the induction of acute pancreatitis (AP), amylase and lipase in plasma significantly increased in all animals in …
The Problem Of Lipid Exchange In Vessel Walls In Insulin Deficit, Gulchekhra M. Irgasheva, Lyudmila Sergeevna Klemesheva, Karim Tadjibaevich Almatov
The Problem Of Lipid Exchange In Vessel Walls In Insulin Deficit, Gulchekhra M. Irgasheva, Lyudmila Sergeevna Klemesheva, Karim Tadjibaevich Almatov
Turkish Journal of Medical Sciences
It has been revealed that in alloxane diabetes the content of the main phospholipids - phosphatidylcholine, phosphatidyletanolamine and phosphatidyl-phosphatidylinosite -decreases in the cells of the vascular wall, whereas the content of the methyl ethers of the fatty acids is not changed, and the content of the fractions of lipids (monoglycerides, diglycerides, triglycerides, cholesterol, free fatty acids, and cholesterol ethers) and phospholipids (phosphatidylserine, cardiolipin, lysophosphatidyletanolamine, lysocardiolipin, sphingomyelin, phosphatide acid and lysophosphatide acid) increase. The depth of these changes correlates with the heaviness of the pathological process.
Effects Of Short-Term Orlistat Therapy On Maximal Power Production Capacity In Obese Patients, Oğuz Özçeli̇k, Rami̇s Çolak, A. Baki̇ Türkoğlu
Effects Of Short-Term Orlistat Therapy On Maximal Power Production Capacity In Obese Patients, Oğuz Özçeli̇k, Rami̇s Çolak, A. Baki̇ Türkoğlu
Turkish Journal of Medical Sciences
The aim of this study was to examine the effects of weight loss induced by hypocaloric diet and orlistat therapy for a four-week period on maximal work rate (Wmax) production capacity and aerobic fitness in obese patients. Fifteen obese subjects were given an integrated energy restricted diet and orlistat supplement (DO). Each patient performed two incremental ramp exercise tests using an electromagnetically braked cycle ergometer: one at the beginning and one at the end of the four-weeks to determine Wmax production capacity. Four weeks of DO therapy resulted in a significant reduction in total body weight (93.7 ± 14.6 kg …
Nondecidualized And Decidualized Endometriosis Of The Abdominal Wall (A Report Of Two Cases Secondary To Cesarean Section), Ni̇hal Kilinç, Ahmet Yalinkaya, Mehmet Özaydin
Nondecidualized And Decidualized Endometriosis Of The Abdominal Wall (A Report Of Two Cases Secondary To Cesarean Section), Ni̇hal Kilinç, Ahmet Yalinkaya, Mehmet Özaydin
Turkish Journal of Medical Sciences
LINÇ Ahmet YALINKAYA Mehmet ÖZAYDIN Department of Pathology, Faculty of Medicine, Dicle University, Diyarbakır - TURKEY
Investigation Of The Antiviral Effect Of Vepesid On Hsv Type 2, Adi̇l M. Allahverdi̇yev, Ni̇zami̇ Duran, Öznur Uyanik
Investigation Of The Antiviral Effect Of Vepesid On Hsv Type 2, Adi̇l M. Allahverdi̇yev, Ni̇zami̇ Duran, Öznur Uyanik
Turkish Journal of Medical Sciences
Objective: Vepesid is a semisynthetic derivative of phodophylotoxin extracted from Phodophylum peltatum, which is in the group of plant alkaloids. In this study, the antiviral effect of Vepesid against herpes simplex virus type 2 (HSV-2) in in vitro conditions was investigated. Materials and Methods: In this investigation, a HEp-2 continuous cell line that was derived from human larynx cancer cells was used. The experiments were done in culture plates with smooth bases consisting of 96 wells. Cultivation of cells was realized in EMEM medium with 10% fetal bovine serum at an atmosphere of 37°C with 5% CO_2. The toxicity of …
Invasive Pulmonary Aspergillosis In Solid-Organ Transplant Recipients: Postmortem Histopathologic Findings, Banu Bi̇lezi̇kçi̇, Beyhan Demi̇rhan, Asuman Ni̇han Haberal, Ünser Arikan
Invasive Pulmonary Aspergillosis In Solid-Organ Transplant Recipients: Postmortem Histopathologic Findings, Banu Bi̇lezi̇kçi̇, Beyhan Demi̇rhan, Asuman Ni̇han Haberal, Ünser Arikan
Turkish Journal of Medical Sciences
Invasive aspergillosis is often lethal in transplant recipients. The mortality associated with this disease after organ transplantation approaches 100%, partly because it is difficult to recognize and diagnose early on. The clinical course and histological findings in invasive pulmonary aspergillosis in immunocompromised hosts differ from those seen in patients who develop classic aspergillomas. In immunosuppressed patients, the predominant pathologic abnormalities are tissue invasion, abscess formation, and angioinvasion with or without infarction. In this study, we examined cases of invasive pulmonary aspergillosis in one kidney recipient and three liver transplant recipients. All the patients were male, and their mean age was …
A Survey Of Patients With Acute Poisoning In The Sivas Region, Turkey, Between 1994 And 1998, Hakan Alagözlü, Hafi̇ze Sezer, Ferhan Candan, Ertan Tabak, Nazi̇f Elaldi
A Survey Of Patients With Acute Poisoning In The Sivas Region, Turkey, Between 1994 And 1998, Hakan Alagözlü, Hafi̇ze Sezer, Ferhan Candan, Ertan Tabak, Nazi̇f Elaldi
Turkish Journal of Medical Sciences
This study was carried out over the period 1994-1998 for the purpose of observing the poisoning incidence and of presenting a poisoning profile of the Sivas region, Turkey. During the study period, 1521 patients were admitted to hospitals with various poisonings in Sivas and these were retrospectively analyzed. The results were evaluated by a chi-square test. In 1521 (1054 females, 467 males) poisoning cases, the mean annual incidence of poisonings was found to be 0.048%. When poisoning cases were assessed etiologically, drug poisonings rated first (54.8%). The most commonly ingested drugs were antidepressants (39%), analgesic-antiinflammatories (31%), antihypertensives (7%) and miscellaneous …
Effects Of Increased Respiratory Resistance On Maximal O_2 Uptake And Anaerobic Threshold During Incremental Exercise Tests, Oğuz Özçeli̇k, Rami̇s Çolak
Effects Of Increased Respiratory Resistance On Maximal O_2 Uptake And Anaerobic Threshold During Incremental Exercise Tests, Oğuz Özçeli̇k, Rami̇s Çolak
Turkish Journal of Medical Sciences
This study was undertaken to assess whether maximal O_2 uptake (VO_2max) can be used as an index of measuring aerobic capacity under the condition of increased respiratory resistance. Seven male subjects performed two incremental exercise tests on a cycle ergometer on different days: one control (C) and one breathing through an 8 mm bore diameter respiratory resistance (R). Ventilatory and gas exchange responses were measured with a turbine volume transducer and mass spectrometry, and processed breath-by-breath. VO_2max was measured and anaerobic threshold (AT) was estimated non-invasively using the V-slope method. Maximal exercise performance was reduced significantly (by paired t-test, P
The Effects Of Three Neurosurgical Anaesthetic Methods On Hla-Dr Expression, Nusa Tuna, Meti̇n Tuna, Demet Koca, Şebnem Atici, Aniş Ariboğan
The Effects Of Three Neurosurgical Anaesthetic Methods On Hla-Dr Expression, Nusa Tuna, Meti̇n Tuna, Demet Koca, Şebnem Atici, Aniş Ariboğan
Turkish Journal of Medical Sciences
Expression of human leukocyte antigen-DR (HLA-DR) is considered a meaningful indicator of immune response because of the important role that HLA-DR plays in presenting antigen to T-lymphocytes. The aim of this study was to evaluate the effects of three anaesthetic methods (intravenous anaesthesia with propofol-fentanyl and balanced anaesthesia with isoflurane-fentanyl or sevoflurane-fentanyl) on monocytic HLA-DR expression in neurosurgical patients who underwent craniotomy. Thirty patients were divided into 3 groups of 10, and each group was the subject of one of the anaesthetic regimes noted above during craniotomy procedures. Blood samples were collected and HLA-DR expression was measured by flow cytometry …
Congenital Pseudoarthrosis Of The Clavicle With Multiple Vertebral Anomalies, Ahmet Yi̇ği̇t Göktay, Mustafa Seçi̇l, Erki̇n Çeti̇nkol, Di̇nç Özaksoy
Congenital Pseudoarthrosis Of The Clavicle With Multiple Vertebral Anomalies, Ahmet Yi̇ği̇t Göktay, Mustafa Seçi̇l, Erki̇n Çeti̇nkol, Di̇nç Özaksoy
Turkish Journal of Medical Sciences
ğit GÖKTAY Mustafa SEÇİL Erkin ÇETİNKOL Dinç ÖZAKSOY Department of Radiology, Faculty of Medicine, Dokuz Eylül University, İzmir - TURKEY
Psoas Abscess Secondary To Brucellar Spondylitis, Bi̇lgehan Aygen, Duygu Eşel, Nuri̇ Erdoğan, Orhan Yildiz, Bülent Sümerkan, Mehmet Doğanay
Psoas Abscess Secondary To Brucellar Spondylitis, Bi̇lgehan Aygen, Duygu Eşel, Nuri̇ Erdoğan, Orhan Yildiz, Bülent Sümerkan, Mehmet Doğanay
Turkish Journal of Medical Sciences
No abstract provided.
Production And Purification Of Monoclonal Antibodies To Human Interleukin-2 And Their Use For Immunoaffinity Purification Of Recombinant Human Interleukin-2, Cemaletti̇n Aybay
Production And Purification Of Monoclonal Antibodies To Human Interleukin-2 And Their Use For Immunoaffinity Purification Of Recombinant Human Interleukin-2, Cemaletti̇n Aybay
Turkish Journal of Medical Sciences
Monoclonal antibodies (mAbs) are a powerful immunochemical tool. Today, the availability of mAbs with desired specificity enables ligand separation based upon the immunoaffinity technique. By using the high selectivity of mAbs, immunoaffinity purification offers the possibility of isolating compounds even from complex samples with a selectivity which cannot be achieved by other methods. This paper reports the preparation and identification of monoclonal antibodies against human interleukin-2 (IL-2) and the establishment of an immunoaffinity method for purifying human IL-2 (hIL-2). Hybridomas were generated by the fusion of NSO or FO myelomas and spleen cells from immunized mice. Hypoxanthine-aminopterin-thymidine-resistant hybridomas secreting antibodies …
The Relation Between Low-Density Lipoprotein (Ldl) Oxidation And Hemodialysis With Respect To Membrane Types Protective Effects Of Vitamin E-Bonded Membrane, Selda Demi̇rtaş, Gökhan Nergi̇soğlu, Ayşegül Akbay Yarpuzlu, Levent Karaca
The Relation Between Low-Density Lipoprotein (Ldl) Oxidation And Hemodialysis With Respect To Membrane Types Protective Effects Of Vitamin E-Bonded Membrane, Selda Demi̇rtaş, Gökhan Nergi̇soğlu, Ayşegül Akbay Yarpuzlu, Levent Karaca
Turkish Journal of Medical Sciences
Plasma total antioxidant (TAO) levels, LDL (low density lipoprotein), antioxidant defense potential (AOP) and the resistance to oxidation of LDL fractions were studied in chronic hemodialysis patients. The differences with respect to dialyzer membrane types before and after hemodialysis were also assessed. After isolation of LDL from plasma by precipitation, AOP was measured based on the determination of TBARS (thiobarbituric acid reactive substance), and resistance to oxidation was assessed by the metal-catalyzed peroxidation of LDL followed by the determination of the values of the peroxidation product malondialdehide (MDA) before and after peroxidation. The assay principle of TAO was based on …
Discrimination Between The Acidic And Molecular Effects Of Lactate On Muscle Tension Development, Şeref Erdoğan, Sanli Sadi̇ Kurdak, Ni̇lay Ergen, Ayşe Doğan
Discrimination Between The Acidic And Molecular Effects Of Lactate On Muscle Tension Development, Şeref Erdoğan, Sanli Sadi̇ Kurdak, Ni̇lay Ergen, Ayşe Doğan
Turkish Journal of Medical Sciences
Fatigue can be defined as the decrease in the genesis of maximal muscle tension, and it may develop when metabolic end-products cannot be readily washed out. During anaerobic exercises, lactate accumulates in the muscle and blood, resulting in acidic pH in these tissues. Fatigue during lactate accumulation is generally attributed to its acidifying property; however, the inverse effect of lactate on muscle tension also at isopH values may be due to the molecular as well as the acidifying effects of this metabolite. In this study, we aimed to distinguish the molecular and acidifying effects of high lactate, both of which …