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Articles 4111 - 4140 of 8080
Full-Text Articles in Medicine and Health Sciences
Ocular Surface Culture Changes In Patients After Septoplasty, Mahmut Özkiriş, Zeli̇ha Kapusuz Gencer, Çi̇ğdem Kader, Levent Saydam
Ocular Surface Culture Changes In Patients After Septoplasty, Mahmut Özkiriş, Zeli̇ha Kapusuz Gencer, Çi̇ğdem Kader, Levent Saydam
Turkish Journal of Medical Sciences
To investigate the interrelationships between pre- and postoperative microbiological changes by taking samples from both eyes of 40 patients who underwent septoplasty due to septal deviation. Materials and methods: Forty patients diagnosed with septal deviation who underwent a septoplasty operation under general anesthesia were enrolled in this study. The study was conducted on 40 patients who met the inclusion criteria and attended follow-up visits. One day before the operation and 48 h after the operation, cultures were taken individually from the conjunctivas and puncta of both eyes and sent to the microbiology laboratory. Results: Patients who were candidates for nasal …
An Investigation Of Pulmonary Findings Of Crimean-Congo Haemorrhagic Fever Patients, Gülden Bi̇lgi̇n, Çi̇ğdem Ataman Hati̇poğlu, Şeri̇fe Altun, Cemal Bulut, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz
An Investigation Of Pulmonary Findings Of Crimean-Congo Haemorrhagic Fever Patients, Gülden Bi̇lgi̇n, Çi̇ğdem Ataman Hati̇poğlu, Şeri̇fe Altun, Cemal Bulut, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
Crimean-Congo haemorrhagic fever (CCHF) generally affects many organs. In this study a retrospective evaluation of the pulmonary findings of CCHF patients was made. Materials and methods: The records of patients were retrospectively analysed. For each patient an evaluation was made of age, sex, occupation, place of residence, contact with ticks, smoking history, and pulmonary radiological and laboratory findings. A confirmed diagnosis of CCHF was made on determination by enzyme-linked immunosorbent assay or polymerase chain reaction. Results: Of the 128 patients, 48.4% were female. Symptoms of coughing were determined in 18% of patients, sputum in 4.7%, chest pain in 3.9%, dyspnoea …
Right-Sided Double-Lumen Tubes: Need For Design Improvement And Better Insertion Technique?, Jean S. Bussieres, Jérôme Lemieux, Jacques Somma
Right-Sided Double-Lumen Tubes: Need For Design Improvement And Better Insertion Technique?, Jean S. Bussieres, Jérôme Lemieux, Jacques Somma
Turkish Journal of Medical Sciences
No abstract provided.
Cystatin C As Biomarker Of Contrast-Induced Nephropathy In Pediatric Cardiac Angiography, Osman Özdemi̇r, Ayşe Deni̇z Oğuz, Abdülkadi̇r Eren, Ci̇hat Şanli, Hüsnü Oğuz Söylemezoğlu, Ayşe Banu Çayci
Cystatin C As Biomarker Of Contrast-Induced Nephropathy In Pediatric Cardiac Angiography, Osman Özdemi̇r, Ayşe Deni̇z Oğuz, Abdülkadi̇r Eren, Ci̇hat Şanli, Hüsnü Oğuz Söylemezoğlu, Ayşe Banu Çayci
Turkish Journal of Medical Sciences
The purpose of this study is to find the frequency of contrast-induced nephropathy (CIN) and to show the risk factors in the development of CIN and the diagnostic utility of serum cystatin C (CysC) and serum and urine neutrophil gelatinase-associated lipocalin (NGAL) during childhood following cardiac angiography. Materials and methods: In this prospective study, we studied 46 children with congenital heart disease. The levels of serum creatinine, serum CysC, and serum NGAL were measured at 4, 24, and 48 h, while levels of urine NGAL and urine creatinine were measured at 4 to 8 and 48 h following cardiac angiography. …
Clinical Manifestations, Complications, And Treatment Of Brucellosis: Evaluation Of 72 Cases, Şükran Köse, Süheyla Seri̇n Senger, Gülgün Akkoçlu, Lütfi̇ye Kuzucu, Yildiz Ulu, Gürsel Ersan, Fi̇li̇z Oğuz
Clinical Manifestations, Complications, And Treatment Of Brucellosis: Evaluation Of 72 Cases, Şükran Köse, Süheyla Seri̇n Senger, Gülgün Akkoçlu, Lütfi̇ye Kuzucu, Yildiz Ulu, Gürsel Ersan, Fi̇li̇z Oğuz
Turkish Journal of Medical Sciences
Brucellosis is an important disease in developing countries. We aimed to determine the epidemiologic, clinical, and laboratory characteristics of brucellosis, which still has a high morbidity in Turkey. Materials and methods: Seventy-two patients with brucellosis, monitored at our clinic from January 2004 to July 2010, were reviewed retrospectively. Results: The average age was determined to be 44.8 ± 18 years, and 40 of the patients were female (55.6%). The most frequent transmission route was the use of raw milk and dairy products, in 45 of the patients (62.5%). The most frequent complaints were joint pain, high fever, weakness, low back …
Thromboelastography In The Evaluation Of Coagulation Disorders In Patients With Sepsis, Yeli̇z Kiliç, İsmet Topçu, Hamza Bambal, Melek Çi̇vi̇
Thromboelastography In The Evaluation Of Coagulation Disorders In Patients With Sepsis, Yeli̇z Kiliç, İsmet Topçu, Hamza Bambal, Melek Çi̇vi̇
Turkish Journal of Medical Sciences
Unbalanced hemostasis and disseminated intravenous coagulopathy serve as key participants in organ dysfunction and disability. In this study we evaluated the coagulation profiles of patients diagnosed with systemic inflammatory syndrome (SIRS)-sepsis and multiple organ dysfunction syndrome. We also researched coagulation in sepsis by comparing thromboelastography (TEG) data with those of nonsepsis patients to determine the usefulness of the TEG device. Materials and methods: Data were collected from 55 anesthesiology and surgery intensive care unit (ICU) patients: 21 with SIRS-sepsis (Group S) and 34 patients without SIRS-sepsis (Group C). Blood samples were taken upon admission to the ICU (t1) and on …
Epidemiology Of Organophosphate Intoxication And Predictors Of Intermediate Syndrome, Şahi̇n Çolak, Mehmet Özgür Erdoğan, Ahmet Baydin, Mustafa Ahmet Afacan, Celal Kati, Lati̇f Duran
Epidemiology Of Organophosphate Intoxication And Predictors Of Intermediate Syndrome, Şahi̇n Çolak, Mehmet Özgür Erdoğan, Ahmet Baydin, Mustafa Ahmet Afacan, Celal Kati, Lati̇f Duran
Turkish Journal of Medical Sciences
To evaluate the usefulness of plasma glucose and serum cholinesterase levels as predictors of organophosphate-induced intermediate syndrome. Materials and methods: Seventy-one organophosphate poisoning patients who were admitted to our emergency department during a 4-year period were evaluated retrospectively. Four patients were excluded from the study due to a lack of medical records. Categorical variables were analyzed using the chi-square test and nonparametric variables were analyzed using the Mann-Whitney U test. Results: Thirty-five (52.2%) patients were male and 32(47.8%) were female. Patients had a mean age of 39.4 ± 15.9 years and 70.1% of the patients were married. Oral intake (68.7%) …
Efficacy Of Resuscitation With Intralipid In A Levobupivacaine-Induced Cardiac Arrest Model, Murat Karcioğlu, Kasim Tuzcu, Fati̇h Sefi̇l, Işil Davarci, Suzan Aydin, Ali̇ Sari, Akin Aydoğan, Rai̇f Özden
Efficacy Of Resuscitation With Intralipid In A Levobupivacaine-Induced Cardiac Arrest Model, Murat Karcioğlu, Kasim Tuzcu, Fati̇h Sefi̇l, Işil Davarci, Suzan Aydin, Ali̇ Sari, Akin Aydoğan, Rai̇f Özden
Turkish Journal of Medical Sciences
Cardiac toxicity due to the administration of local anesthetics may be fatal. In this study, we evaluated the efficacy of a 20% lipid solution combined with epinephrine in a levobupivacaine-induced cardiac arrest model. Materials and methods: A total of 14 New Zealand rabbits were sedated and mechanically ventilated. Asystole was induced with intravenous levobupivacaine injection. The rabbits were randomized into groups receiving the same volume of either 0.9% saline (CR group) or a 20% lipid solution (LE group) along with a 100 µg/kg epinephrine bolus, which were administered immediately upon asystole. Standard advanced cardiac life support protocols were performed. Results: …
The Expression Of Egfr, Cerbb2, P16, And P53 And Their Relationship With Conventional Parameters In Squamous Cell Carcinoma Of The Larynx, Hülya Şi̇mşek, Ünsal Han, Bi̇nnur Önal, Gülçi̇n Şi̇mşek
The Expression Of Egfr, Cerbb2, P16, And P53 And Their Relationship With Conventional Parameters In Squamous Cell Carcinoma Of The Larynx, Hülya Şi̇mşek, Ünsal Han, Bi̇nnur Önal, Gülçi̇n Şi̇mşek
Turkish Journal of Medical Sciences
To investigate the expression of epidermal growth factor receptor¬-HER1 (EGFR), cerbB2 (HER2), p16, and p53, as well as the relationship of the expression of these genes with conventional parameters in squamous cell carcinoma (SCC) of the larynx. Materials and methods: Samples from 92 cases of diagnosed laryngeal SCC between 2001 and 2011 from the Pathology Department of Ministry of Health Ankara Dışkapı Yıldırım Beyazıt Teaching & Research Hospital were studied by immunohistochemistry using EGFR, cerbB2, p16, and p53 antibodies. Results: An increase in the TNM stage and pathological tumor size status correlated with an increase in EGFR and cerbB2 expression. …
Immunohistochemical Investigation Of Galectin-3 In The Skin Of Mice Applied With Origanum Hypericifolium Essential Oil And Irradiated With Ultraviolet B, Pinar İli̇, Nazan Keski̇n
Immunohistochemical Investigation Of Galectin-3 In The Skin Of Mice Applied With Origanum Hypericifolium Essential Oil And Irradiated With Ultraviolet B, Pinar İli̇, Nazan Keski̇n
Turkish Journal of Medical Sciences
To demonstrate galectin-3-immunoreactivity in the undiluted essential oil of Origanum hypericifolium when applied to the ultraviolet B (UVB) irradiated skin of mice. Materials and methods: Female BALB/c mice were allocated to 4 groups, each comprising 6 mice (Group 1: control; Group 2: UVB irradiated control; Group 3: undiluted O. hypericifolium essential oil applied; Group 4: undiluted O. hypericifolium essential oil applied before UVB irradiation). One week prior to UVB irradiation, the undiluted O. hypericifolium essential oil was applied to the shaved dorsal skin of mice 3 times a week. Subsequently, the mice were irradiated 3 times per week with UVB …
Comparison Of Cutaneous Mastocytosis With Onset In Children And Adults, Serap Güneş Bi̇lgi̇li̇, Ayşe Serap Karadağ, Zennure Takci, Ömer Çalka, Mustafa Kösem
Comparison Of Cutaneous Mastocytosis With Onset In Children And Adults, Serap Güneş Bi̇lgi̇li̇, Ayşe Serap Karadağ, Zennure Takci, Ömer Çalka, Mustafa Kösem
Turkish Journal of Medical Sciences
Mastocytosis is a heterogeneous group of diseases characterized by the abnormal infiltration of mast cells in the skin and sometimes other organs. This study aimed to compare the demographic, clinical, and histopathological findings of cutaneous mastocytosis with onset in children and in adults. Materials and methods: Patients diagnosed with cutaneous mastocytosis in 2 different dermatology clinics between 2007 and 2011 were included in the study. Demographic characteristics of the patients as well as localization and type of the cutaneous lesions, presence of symptoms, Darier's sign, family history, systemic involvement, and histopathological evaluations were retrospectively examined. Results: Out of the 30 …
Effects Of Linoleic Acid On Generalized Convulsive And Nonconvulsive Epileptic Seizures, Fati̇h Eki̇ci̇, Gönül Gürol, Nurbay Ateş
Effects Of Linoleic Acid On Generalized Convulsive And Nonconvulsive Epileptic Seizures, Fati̇h Eki̇ci̇, Gönül Gürol, Nurbay Ateş
Turkish Journal of Medical Sciences
To comparatively investigate the effects of linoleic acid on convulsive and nonconvulsive epileptic seizures. Materials and methods: Rats were divided into 3 groups: convulsive epileptic rats receiving only pentylentetrazole (PTZ) injections (group 1), convulsive epileptic rats receiving PTZ and linoleic acid (group 2), and Wistar Albino Glaxo rats from Rijswijk with genetic absence epilepsy receiving linoleic acid (group 3). The duration and severity of convulsive activity were determined in groups in which convulsive seizures were induced by PTZ. In group 3, intravenous linoleic acid was administered after 1-h baseline electroencephalography (EEG) recordings. The EEG recordings were analyzed. Results: When groups …
Endocrine Abnormalities Of Patients With Cleft Lip And/Or Cleft Palate During The Neonatal Period, Mustafa Ali̇ Akin, Seli̇m Kurtoğlu, Di̇lek Sarici, Leyla Akin, Ni̇hal Hati̇poğlu, Levent Korkmaz, Tamer Güneş, Mehmet Adnan Öztürk, Mustafa Akçakuş
Endocrine Abnormalities Of Patients With Cleft Lip And/Or Cleft Palate During The Neonatal Period, Mustafa Ali̇ Akin, Seli̇m Kurtoğlu, Di̇lek Sarici, Leyla Akin, Ni̇hal Hati̇poğlu, Levent Korkmaz, Tamer Güneş, Mehmet Adnan Öztürk, Mustafa Akçakuş
Turkish Journal of Medical Sciences
There are close interactions among the developing oral cavity, pituitary gland, and central nervous system (CNS) in early embryonic life. In this study we aimed to screen endocrine abnormalities in patients with orofacial clefts in the neonatal period. Materials and methods: Thirty-one patients with isolated orofacial median clefts were included in the study. Pituitary, thyroid, and adrenal hormones were measured at the first week and remeasured in the third or fourth weeks. Imaging studies were done for detection of CNS anomalies in all patients. Results: Endocrine abnormality was detected in 22 (70.9%) patients. The number of patients with single and …
Anesthetic Management And Perioperative Complications In Transcatheter Aortic Valve Implantation: The Turkish Experience, Tüli̇n Gümüş, Elvi̇n Kesi̇mci̇, Cem Soykut, Orhan Kanbak, Abdulkadi̇r But
Anesthetic Management And Perioperative Complications In Transcatheter Aortic Valve Implantation: The Turkish Experience, Tüli̇n Gümüş, Elvi̇n Kesi̇mci̇, Cem Soykut, Orhan Kanbak, Abdulkadi̇r But
Turkish Journal of Medical Sciences
To describe the anesthetic management and early results of transcatheter aortic valve implantation (TAVI) in a single center in Turkey. Materials and methods: We evaluated 79 (54 females, 25 males; mean age: 76 ± 9 years) consecutive symptomatic patients with severe aortic stenosis who underwent TAVI under general anesthesia between July 2011 and September 2012. We preferred a transfemoral approach as the first option. Results: The duration of anesthesia was 149 ± 49 min. Thirty-eight percent of the patients were extubated in the cardiac catheterization laboratory. Three patients required a permanent pacemaker, while 8 patients required inotropic support in the …
The Effect Of Dietary Salt Restriction On Hypertension In Peritoneal Dialysis Patients, Sali̇h İnal, Yasemi̇n Erten, Ni̇lüfer Tek, Gülay Ulusal Okyay, Kürşad Öneç, Gamze Akbulut, Nevi̇n Şanlier
The Effect Of Dietary Salt Restriction On Hypertension In Peritoneal Dialysis Patients, Sali̇h İnal, Yasemi̇n Erten, Ni̇lüfer Tek, Gülay Ulusal Okyay, Kürşad Öneç, Gamze Akbulut, Nevi̇n Şanlier
Turkish Journal of Medical Sciences
To investigate the effect of dietary salt restriction on blood pressure levels, total sodium removal, and hydration status of peritoneal dialysis (PD) patients. Materials and methods: Thirty-one stable PD patients who consulted a renal dietitian monthly for dietary recommendations, including restricted salt intake 0.05) for the whole sample, and from 164.3 ± 70.9 to 154.2 ± 72.3 mmol/day (P > 0.05) for the hypertensive subgroup (n: 17). Systolic blood pressure (from 134.3 ± 20.1 to 127.2 ± 19.5 mmHg, P: 0.01), diastolic blood pressure (from 83.2 ± 12.0 to 77.4 ± 10.5 mmHg, P: 0.01) and total body water (from 39.2 …
Discovering Missing Heritability And Early Risk Prediction For Type 2 Diabetes: A New Perspective For Genome-Wide Association Study Analysis With The Nurses' Health Study And The Health Professionals' Follow-Up Study, Hüsametti̇n Gül, Yeşi̇m Aydin Son, Cengi̇zhan Açikel
Discovering Missing Heritability And Early Risk Prediction For Type 2 Diabetes: A New Perspective For Genome-Wide Association Study Analysis With The Nurses' Health Study And The Health Professionals' Follow-Up Study, Hüsametti̇n Gül, Yeşi̇m Aydin Son, Cengi̇zhan Açikel
Turkish Journal of Medical Sciences
Despite the rise in type 2 diabetes prevalence worldwide, we do not have a method for early risk prediction. The predictive ability of genetic models has been found to be little or negligible so far. In this study, we aimed to develop a better early risk prediction method for type 2 diabetes. Materials and methods: We used phenotypic and genotypic data from the Nurses' Health Study and Health Professionals' Follow-up Study cohorts and analyzed them by using binary logistic regression. Results: Phenotypic variables yielded 70.7% overall correctness and an area under the curve (AUC) of 0.77. With regard to genotype, …
The Validity And Reliability Of The Turkish Version Of The University Of Toronto Atrial Fibrillation Severity Scale, Ni̇han Kahya Eren, Selcen Yakar Tülüce, Bariş Kiliçaslan, Cem Nazli, Asim Oktay Ergene
The Validity And Reliability Of The Turkish Version Of The University Of Toronto Atrial Fibrillation Severity Scale, Ni̇han Kahya Eren, Selcen Yakar Tülüce, Bariş Kiliçaslan, Cem Nazli, Asim Oktay Ergene
Turkish Journal of Medical Sciences
There are various instruments to assess quality of life (QoL) in patients with atrial fibrillation (AF). The aim of this study is to determine the reliability and validity of the Turkish version of the University of Toronto Atrial Fibrillation Severity Scale (AFSS). Materials and methods: The AFSS and Short Form-36 (SF-36) were completed by 130 patients with documented AF. The Canadian Cardiovascular Society Severity in Atrial Fibrillation (SAF) scale and European Heart Rhythm Association (EHRA) scale were also utilized by the attending physicians. To assess test-retest reliability, the AFSS was readministered to 47 clinically stable patients at a 1-month follow-up …
Evaluation Of Ovsynch Protocols For Timed Artificial Insemination In Water Buffaloes In Bangladesh, Md Nazmul Hoque, Anup Kumar Talukder, Masuma Akter, Mohammed Shamsuddin
Evaluation Of Ovsynch Protocols For Timed Artificial Insemination In Water Buffaloes In Bangladesh, Md Nazmul Hoque, Anup Kumar Talukder, Masuma Akter, Mohammed Shamsuddin
Turkish Journal of Veterinary & Animal Sciences
A total of 65 water buffaloes (groups A, B, and C) at =>60 days postpartum with a body condition score (BCS) of =>2.5 were selected to evaluate ovsynch protocols for timed artificial insemination (TAI). The group A buffaloes (n = 25) were treated with a simple ovsynch protocol (GnRH - Day 7 - PGF2 alpha - Day 2 - GnRH -16 h - TAI). The group B buffaloes (n = 22) received PGF2 alpha treatment 12 days before the initiation of simple ovsynch (PGF2 alpha at Day -12 + simple ovsynch; modified ovsynch). The group C buffaloes (n …
Application Of Dietary Fish Oil In Dairy Cow Reproduction, Anna Zwyrzykowska, Robert Kupczynski
Application Of Dietary Fish Oil In Dairy Cow Reproduction, Anna Zwyrzykowska, Robert Kupczynski
Turkish Journal of Veterinary & Animal Sciences
Feed fats are commonly used as a component of high-yielding cow diet rations. Many studies have been conducted on the effects of fat supplementation on metabolism, milk composition, and improvements in dairy cow reproduction. The positive effects on fat (vegetable oil) and energy supplementation on improvements in reproduction are well documented. Consumption of polyunsaturated fatty acids (PUFAs), including n-3 acids, in appropriate feed doses improves fertility of dairy cows. A fat source with high levels of acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is marine oil, especially fish and algae. By modification of cow rations, EPA and …
Molecular, Cellular, And Physiological Determinants Of Bull Fertility, Alexis Marie Parisi, Shannon Kate Thompson, Abdullah Kaya, Erdoğan Memi̇li̇
Molecular, Cellular, And Physiological Determinants Of Bull Fertility, Alexis Marie Parisi, Shannon Kate Thompson, Abdullah Kaya, Erdoğan Memi̇li̇
Turkish Journal of Veterinary & Animal Sciences
Bull fertility, defined as the ability of the spermatozoon to fertilize and activate the ovum and then support embryonic and even fetal development, is a crucial factor influencing animal reproduction and production efficiency. Despite significant influences of fertility on herd genetic improvement and efficient cattle production, the mechanisms regulating this phenotype and reliable biomarkers associated with bull fertility are poorly defined. Specifically, there is a broad lack of knowledge in bull fertility. In this paper, bull fertility is reviewed within the context of animal systems physiology, and system biology markers associated with bull fertility are provided. This mini-review is intended …
Cholesterol Efflux From Sperm: Approaches And Applications, Zahid Naseer, Ejaz Ahmad, Meli̇h Aksoy
Cholesterol Efflux From Sperm: Approaches And Applications, Zahid Naseer, Ejaz Ahmad, Meli̇h Aksoy
Turkish Journal of Veterinary & Animal Sciences
Following ejaculation, sperm appear morphologically mature, but functionally they are inactive. To attain functional capability or capacitation in vivo, sperm must reside in the female reproductive tract for a certain period of time before fertilization. In the female reproductive tract, cholesterol efflux from the sperm plasma membrane is considered vital for the initiation of capacitation. A number of in vitro studies have used biological and nonphysiological means to understand the phenomenon of cholesterol efflux and capacitation. In this review, we present a short overview of the role of cholesterol efflux in regulating sperm capacitation using various agents. This review provides …
The Effect Of Short-Term Lupin (Lupinus Angustifolius) Feed Supplementation On Serum Steroid Hormones, Insulin-Like Growth Factor I, And Ovarian Follicular Development And Atresia In Merino Ewes, Radoslava Vlckova, Jan Posivak, Igor Valocky, Zuzana Kravcova, Andrea Eibenová, Drahomia Sopkova
The Effect Of Short-Term Lupin (Lupinus Angustifolius) Feed Supplementation On Serum Steroid Hormones, Insulin-Like Growth Factor I, And Ovarian Follicular Development And Atresia In Merino Ewes, Radoslava Vlckova, Jan Posivak, Igor Valocky, Zuzana Kravcova, Andrea Eibenová, Drahomia Sopkova
Turkish Journal of Veterinary & Animal Sciences
The effects of short-term lupin supplementation on ovulation rate in ewes during oestrous season are well known. In this study, we tested the effects of an 8-day lupin supplementation on folliculogenesis during anoestrus applied over the hormonal treatment of ewes. Fourteen anoestrous Merino ewes were assigned into 2 groups (n = 7 for each) in which the control group was fed a basal diet and the experimental group was supplemented with lupin groats (500 g per head per day). Both groups were treated intramuscularly with 12.5 µg/head lecirelinum (luteinising hormone releasing hormone super analogue) on the first day of supplementation …
Expression Of Vascular Endothelial Growth Factor And Hypoxia-Inducible Factor-1 Alpha During The Periovulatory Period In Goats, Chainarong Navanukraw, Jiratti Thammasiri, Tossapol Moonmanee, Jaruk Nutthakornkul
Expression Of Vascular Endothelial Growth Factor And Hypoxia-Inducible Factor-1 Alpha During The Periovulatory Period In Goats, Chainarong Navanukraw, Jiratti Thammasiri, Tossapol Moonmanee, Jaruk Nutthakornkul
Turkish Journal of Veterinary & Animal Sciences
To evaluate the expression of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor-1 alpha (HIF-1 alpha) during the periovulatory period, goat ovaries were collected at 0, 4, 8, 12, 24, and 48 h after treatment with 300 IU hCG. Total cellular RNA was isolated and VEGF and HIF-1 alpha were quantified using real-time RT-PCR. The mRNA levels of VEGF in thecal tissue remained unchanged prior to ovulation. However, the mRNA levels of VEGF in thecal tissues at 48 h increased to 7.5-fold of the level at 0 h (P < 0.05). In granulosa tissue, the VEGF mRNA levels were not detected in granulosa cells at 48 h. In thecal tissue, the mRNA level of HIF-1 1 alpha at 4 h was 1.5-fold of the level at 0 h and remained unchanged during 8-24 h; however the levels were significantly increased at 48 h. The mRNA levels of HIF-1 alpha in granulosa at 4 h was not changed but levels were increased (P < 0.05) at 8 h and at 12 h and then decreased at 24 and 48 h, respectively. These data describe the relationships of VEGF- and HIF-1 alpha -dependent angiogenesis during the periovulatory periods by which hypoxia during ovulation is crucial for establishing the thecal new vasculature.
Activity Of 3\Beta-Hydroxysteroid Dehydrogenase Associated With Progesterone Production In Bovine Granulosa Cells Cultured Under Different Concentrations Of Serum, Insulin-Like Growth Factor I, And Gonadotropin, Özkan Şi̇mşek, Monika Mihm
Activity Of 3\Beta-Hydroxysteroid Dehydrogenase Associated With Progesterone Production In Bovine Granulosa Cells Cultured Under Different Concentrations Of Serum, Insulin-Like Growth Factor I, And Gonadotropin, Özkan Şi̇mşek, Monika Mihm
Turkish Journal of Veterinary & Animal Sciences
Three-\beta-hydroxysteroid dehydrogenase (3\beta-HSD) is the enzyme responsible for progesterone production. This study aimed to determine whether 3\beta-HSD activity can be shown to reflect progesterone production by granulosa cells cultured under different serum conditions and follicle stimulating hormone (FSH), luteinising hormone (LH), and insulin-like growth factor I (IGF-I) concentrations. Large bovine follicles were dissected from abattoir ovaries to recover granulosa cells. Cells were washed, stained for viability, and plated for 48 h in basic medium with or without 5% foetal calf serum (FCS). Subsequently, cells were exposed to FSH (1 ng/mL), LH (10 or 100 ng/mL), or FSH (1 ng/mL) + …
Calving Assistance Influences The Occurrence Of Umbilical Cord Pathologies Treated Surgically In Calves, Carlos Moscuzza, Horacio Milicich, Guadalupe Alvarez, Betiana Gutierrez, Mariano Nahum
Calving Assistance Influences The Occurrence Of Umbilical Cord Pathologies Treated Surgically In Calves, Carlos Moscuzza, Horacio Milicich, Guadalupe Alvarez, Betiana Gutierrez, Mariano Nahum
Turkish Journal of Veterinary & Animal Sciences
Ninety-two umbilical pathologies were surgically treated in Holstein, Aberdeen Angus, and Polled Hereford calves, both males and females, whose ages ranged between 2 and 8 months. The pathology diagnosis was performed considering the main anatomical elements involved in the umbilical cord, the inflammation progression, and the macroscopic characteristics of injuries. The umbilical cord pathologies were related to calving characteristics. The proportion of affected umbilical cords in calves born via assisted calving (77%) was significantly higher than that observed in calves born from normal parturition. The umbilical cord pathology of highest occurrence was omphalophlebitis (53.2%). A considerable proportion of infectious diseases …
Association Of Molecular Polymorphism In Exon 2 Of Ovar-Drb1 Gene With Weight Traits In Iranian Makuie Sheep Breed, Fereshteh Ashrafi, Karim Mardani, Ali Hashemi, Reza Darvishzadeh, Mohammad Farhadian
Association Of Molecular Polymorphism In Exon 2 Of Ovar-Drb1 Gene With Weight Traits In Iranian Makuie Sheep Breed, Fereshteh Ashrafi, Karim Mardani, Ali Hashemi, Reza Darvishzadeh, Mohammad Farhadian
Turkish Journal of Veterinary & Animal Sciences
Exon 2 of the Ovar-DRB1 gene of 90 Makuie sheep was amplified and analyzed by polymerase chain reaction and restriction fragment length polymorphism techniques. Ten alleles and 18 genotypes were identified. The frequencies of the genotypes were 0.317, 0.1585, 0.0121, 0.0365, 0.0121, 0.0243, 0.0243, 0.1097, 0.0121, 0.0487, 0.0121, 0.0365, 0.0365, 0.0487, 0.0121, 0.0121, 0.0487, and 0.0365 for AA, AB, AE, FF, AM, BO, EO, IO, OM, AP, BP, OP, PP, AQ, OQ, PQ, QQ, and AV, respectively. Allele frequencies were 0.4756, 0.0976, 0.0183, 0.0366, 0.0549, 0.0122, 0.1098, 0.0915, 0.0854, and 0.0183 for A, B, E, F, I, M, O, P, …
Early Clinical Predictors Of Intractable Epilepsy In Childhood, Semra Saygi, İlknur Erol, Füsun Alehan
Early Clinical Predictors Of Intractable Epilepsy In Childhood, Semra Saygi, İlknur Erol, Füsun Alehan
Turkish Journal of Medical Sciences
In this retrospective study, we evaluated the clinical responses to antiepileptic drug (AED) therapy in pediatric epilepsy patients treated at a single center. Materials and methods: We identified 28 children with intractable epilepsy and 213 patients with drug-responsive epilepsy. Results: Univariate analysis showed that age at onset, high (daily) initial seizure frequency, infantile spasm, history of neonatal seizures, abnormal neurodevelopmental status, neurological abnormalities, mental retardation, remote symptomatic etiology, and abnormal brain imaging results were significant risk factors for the development of intractable epilepsy (P < 0.05). Multivariate logistic regression analysis revealed that high (daily) initial seizure frequency and remote symptomatic etiology were significant and independent risk factors for intractable epilepsy (P < 0.05). Conclusion: Our study suggests that the risk of developing intractable epilepsy in childhood may be predicted, to some extent, by the early clinical course. Early identification of patients at high risk of developing intractable epilepsy will guide appropriate therapy and reduce exposure to ineffectual treatments.
Leiomyoma Of The Esophagus: Open Versus Thoracoscopic Enucleation, Sedat Zi̇yade, Hüseyi̇n Kadioğlu, Şenel Yedi̇yildiz, Nur Büyükpinarbaşili, Ömer Soysal
Leiomyoma Of The Esophagus: Open Versus Thoracoscopic Enucleation, Sedat Zi̇yade, Hüseyi̇n Kadioğlu, Şenel Yedi̇yildiz, Nur Büyükpinarbaşili, Ömer Soysal
Turkish Journal of Medical Sciences
To describe a novel, easy, and secure thoracoscopic surgical approach for esophageal leiomyomas. Materials and methods: We retrospectively analyzed 18 cases in which patients were treated at a single center between 1991 and 2011 for esophageal leiomyoma. We compared our results of patients who were treated by open surgery with those who were treated by the thoracoscopic approach, and we also compared our results with the results of resection of the leiomyoma of the esophagus in the literature. Results: Eighteen patients were studied. Eight patients were treated with 3-port thoracoscopic surgery, 8 with open thoracotomy, 1 with surgical incision, and …
A Pilot Experimental Study Of A Catheter To Facilitate Treatment For Penetrating Cardiac Injury, Mahmut Tokur, Mehmet Ergi̇n, İbrahi̇m Can Kürkçüoğlu, Zerri̇n Defne Dündar
A Pilot Experimental Study Of A Catheter To Facilitate Treatment For Penetrating Cardiac Injury, Mahmut Tokur, Mehmet Ergi̇n, İbrahi̇m Can Kürkçüoğlu, Zerri̇n Defne Dündar
Turkish Journal of Medical Sciences
Penetrating heart injuries result in high mortality. We designed a new catheter to facilitate the treatment of penetrating cardiac injuries and provide more effective initial bleeding control and fluid replacement. Materials and methods: The cardiac injury model was applied to 8 female 1-year-old Sus domesticus pigs. Subjects were grouped according to whether a Foley catheter or a newly designed catheter was placed into the heart through cardiac lacerations. Changes in systolic blood pressures, mortality, and problems encountered during surgery and other intraoperative findings were recorded. Results: There were higher mean blood pressure measurements in the newly designed catheter group during …
Investigation Into The Frequency Of Helicobacter Pylori Infection With Carbon 14 Urea Breath Test In Patients With Vitiligo, Emi̇ne Nur Ri̇fai̇oğlu, Füsun Aydoğan, Bi̇lge Bülbül Şen, Tuğba Şen, Özlem Eki̇z
Investigation Into The Frequency Of Helicobacter Pylori Infection With Carbon 14 Urea Breath Test In Patients With Vitiligo, Emi̇ne Nur Ri̇fai̇oğlu, Füsun Aydoğan, Bi̇lge Bülbül Şen, Tuğba Şen, Özlem Eki̇z
Turkish Journal of Medical Sciences
Vitiligo is a common, acquired depigmenting skin disorder. The relationship between Helicobacter pylori (HP) infection and autoimmune dermatological disease has been previously reported. However, the frequency of HP infection in patients with vitiligo has not been reported. In this study, we aimed to investigate the frequency of HP infection with the carbon 14 (C14) urea breath test (UBT) in patients with vitiligo. Materials and methods: This study included 34 patients (18 males and 16 females) with vitiligo and 30 age- and sex-matched healthy controls. HP infection was diagnosed using the C14 UBT (Heliprobe). Statistical analysis was performed using SPSS 19. …