Medicine and Health Sciences Commons^™

Repair Of An Extensive External Cervical Resorption Lesion Using Intentional Replantation With Crown Rotation., Motoki Okamoto, Yoko Asahi, Henry Fergus Duncan, Nanako Kuriki, Yusuke Takahashi, Mikako Hayashi

HPD Articles

Treatment of large external cervical resorption (ECR) lesions may be compromised, rendering the tooth unrestorable. Intentional replantation is a potential treatment option depending on the site and extent of ECR. We present a case of a large ECR successfully managed with intentional replantation with rotation of the tooth. The female patient consulted the hospital clinic, with an extensive palatal ECR on the maxillary lateral incisor. Routine planar radiographs and cone-beam computed tomography demonstrated a larger palatal than the ECR lesion (Heithersay Class III and Patel's Class 2Bp) not amenable to nonsurgical treatment. Intentional replantation after short-term extrusion was planned. The …

The Emerging Role Of Generative Artificial Intelligence In Medical Education, Research, And Practice., Mohammadali M. Shoja, J. M. Monica Van De Ridder, Vijay Rajput

HPD Articles

Recent breakthroughs in generative artificial intelligence (GAI) and the emergence of transformer-based large language models such as Chat Generative Pre-trained Transformer (ChatGPT) have the potential to transform healthcare education, research, and clinical practice. This article examines the current trends in using GAI models in medicine, outlining their strengths and limitations. It is imperative to develop further consensus-based guidelines to govern the appropriate use of GAI, not only in medical education but also in research, scholarship, and clinical practice.

Tweeting For Success: The Role Of Twitter In Enhancing Scimago Journal Rank For Specialty Surgical Journals., Heli Patel, Justin M. Camacho, Saket Pandit, Gabriella Morey, Davek Sharma, Michael Karon, Amir Behnam

HPD Articles

Background The cornerstone of surgical education and practice is the surgical journal, but the ability to disperse the vital information within their pages had previously been limited. The use of Twitter by surgical journals has increased in recent years and has allowed these journals to reach a wider audience than they previously could. In this article, we discuss the role Twitter engagement has on a journal's impact factor, visibility, and prestige.

Methods The authors compiled a list of journals using the SciMago Journal and Country rank platform. Included journals' Twitter profiles were then assessed using Twitonomy, an online platform that …

The Importance Of Gender-Neutral Terminology In Risk Evaluation And Mitigation Strategy Programs: A Call To Action., Colin Burnette, William Smithy, Daniel Strock, Torunn E. Sivesind, Robert Dellavalle

HPD Articles

The use of risk evaluation and mitigation strategy (REMS) programs is frequently required for prescriptions with potentially teratogenic effects, especially in the field of dermatology. Among these REMS programs, the most well-known example is isotretinoin, an oral retinoid that uses the iPLEDGE system. iPLEDGE has strict regulations and a lengthy approval process, and until recently, patients were grouped into 3 categories: male, female, or female of reproductive potential. This strict grouping has posed problems in the medical community, especially for gender-diverse individuals where their perceived gender conflates with their assigned grouping causing patient-specific distress. The distinction between gender-a multifactorial perception …

Chronic Venous Insufficiency With Emphasis On The Geriatric Population., Harvey N. Mayrovitz, Kawaiola C. Aoki, Jessica Colon

HPD Articles

The underpinning of Chronic Venous Insufficiency (CVI) is valvular dysfunction, which manifests on a spectrum depending on the severity of insufficiency and duration of the disease. The mainstay of treatment relies on compression therapy of a proper type and intensity. In older adults, special consideration must be taken during the patient encounter to account for age-related factors. This review discusses the clinical presentation, diagnosis, and mimicking of CVI, focusing mainly on older adults. The epidemiology, risk factors, disease burden, and grave complications -- such as thrombosis and ulceration, are reviewed. The physiological impacts of CVI are described, providing the background …

Association Between Symptoms Of Severe Periodontitis And Post-Bronchodilator Lung Function: Results From The China Pulmonary Health Study., Zhiqiang Liu, Xuan Zhou, Lirong Liang, Xiaozhe Han, Ting Yang, Kewu Huang, Yingxiang Lin, Zuomin Wang, Chen Wang

HPD Articles

BACKGROUND: The association between periodontitis and post-bronchodilator lung function is unclear. We aimed to determine the associations between symptoms of severe periodontitis (SSP) and post-bronchodilator lung function in the Chinese population.

METHODS: A cross-sectional study (China Pulmonary Health study) was conducted from 2012 to 2015 in a large Chinese nationally representative sample of 49,202 participants aged 20-89 years. Data on demographic characteristics and periodontal symptoms of participants were collected by questionnaire. Participants who had at least one of the two severe symptoms (tooth mobility and natural tooth loss) in the past year were defined to have SSP, which was set …

Periodontal Regeneration Risk Assessment In The Treatment Of Intrabony Defects., Robert A. Levine, Muhammad H A Saleh, Debora R. Dias, Jeffrey Ganeles, Maurício G. Araújo, Franck Renouard, Harold M. Pinsky, Preston D. Miller, Hom-Lay Wang

HPD Articles

BACKGROUND: Regenerative approaches performed in periodontics seems to be efficient in treating intrabony defects. There are, however, many factors that may affect the predictability of the regenerative procedures. The present article aimed to propose a new risk assessment tool for treating periodontal intrabony defects by regenerative therapy.

METHODS: Different variables that could affect the success of a regenerative procedure were considered based on their impact on (i) the wound healing potential, promoting wound stability, cells, and angiogenesis, or (ii) the ability to clean the root surface and maintain an optimal plaque control or (iii) aesthetics (risk for gingival recession).

RESULTS: …

Understanding Mental Health As Public Health, Christi M. Navarro

Faculty Proceedings, Presentations, Speeches and Lectures

In this interactive workshop, we will utilize a multi-level public health framework to illustrate factors of risk and prevention that influence mental health and well-being. We will discuss shifting the narrative of mental health as an individual issue to the responsibility of society, culture, and environment. Participants will reflect on their role and level of influence in this model as well as their potential for action and positive impact.

Noninvasive Continuous Monitoring To Improve Outcome Of Preeclamptic Women Undergoing Spinal Anesthesia For Cesarean Section, Andrea M. Regan, Molly Amin, Josue Brainin Md

Department of Health Sciences Faculty Proceedings, Presentations, Posters, Speeches, Lectures, etc.

Spinal induced hypotension is a common side effect and occurs in up to 33% of patients. Preeclamptic women have a high risk of severe hypotension related to spinal anesthesia while undergoing cesarean section Hypotension, short or cumulative episodes, increase nausea and vomiting in parturient and can potentially result in fetal acidosis, hypoxic-ischemic encephalopathy(HIE), and lower Apgar scores. The recommend standard of care is a minimum of five-minute interval blood pressure monitoring which risks late detection and treatment of hypotension. ClearSight® noninvasive continuous hemodynamic monitoring decreases the risk of hypotension-associated complications in mother and fetus and improves maternal nausea and vomiting …

Obstetric Treatment Of Post Dural Puncture Headaches (Pdph): Less Invasive Alternatives To Epidural Blood Patches (Ebp), Andrea M. Regan, Molly Amin, Josue Brainin Md, Sanjeev Patel Md

Department of Health Sciences Faculty Proceedings, Presentations, Posters, Speeches, Lectures, etc.

Neuraxial labor analgesia for vaginal delivery or cesarean section is performed in more than 71% of women in the United States. Postdural puncture headache(PDPH) is a relatively common complication of neuraxial anesthesia. Epidural blood patch (EBP) is considered the gold standard treatment, and although EBP is a highly effective intervention, it is not without risk. There is growing evidence that less invasive alternative treatments, such as combined use of atropine and neostigmine have effectively relieved PDPH where traditional, conservative methods have failed. The goal is to discover the best method in preventing PDPH and less invasive treatment alternatives compared to …

Potassium-Incorporated Titanium Oxide Nanoparticles Modulate Human Dendritic Cell Immune Response To Mycobacterium Leprae, Sam Warren, So Yoon Lee, Jose Barragan, Piya Kositangool, Hatsuko Yoshikubo, Jorge Cervantes

HPD Articles

The two polar clinical forms of leprosy, termed tuberculoid and lepromatous, have polarized cellular immune responses with complex immunological distinctions. The predominance of DCs in tuberculoid leprosy has been reported, while the lepromatous pattern of illness is associated with weak activation of local populations of DCs. TiO2 nanoparticles have previously been shown to induce maturation of these cells, leading to an inflammatory response similar to adjuvant usage in vaccine administration. We aimed to evaluate the effect of potassium-incorporated Ti oxide nanostructures, namely KTiOxs, in the response of human monocyte-derived DCs to live M. leprae. Human monocytic cell line dual THP-1, …

Barriers Of Care To Ovarian Cancer: A Scoping Review., Zehra Rizvi, Kiran C. Sharma, Viktor Kunder, Adrian Abreu

HPD Articles

Ovarian cancer is a leading cause of female cancer-related deaths, but patients continue to be diagnosed late. This subjects them to disease progression and possible death due to lack of early detection, despite earlier stage detection improving survival rates by significant percentages. Early detection and access to care are closely related. However, many barriers to high-quality care exist for patients and the majority of patients do not receive recommended care according to ovarian cancer treatment guidelines. In order to improve care for ovarian cancer patients and decrease healthcare disparities in accessing equitable care, it is important to acknowledge the current …

Preprocedural Viral Load Effects Of Oral Antiseptics On Sars-Cov-2 In Patients With Covid-19: A Systematic Review., Miriam Ting, Alex Dahlkemper, Jeremy J. Schwartz, Manzel Woodfork, Jon B. Suzuki

HPD Articles

(1) There are limited clinical trials to support the effectiveness of mouth rinses when used as a preprocedural rinse against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This systematic review aims to evaluate the efficacy of antiseptic mouth rinses as a preprocedural rinse in reducing SARS-CoV-2 oral viral load in-vivo. (2) Methods: A literature search was conducted through November 2022 for the following databases: PubMed, Web of Science, Cochrane Library, and Google Scholar. The evaluated outcomes were quantitative changes in viral load and the statistical significance of that change after using antiseptic mouth rinses. (3) Results: 14 randomized controlled trials …

Pneumocephalus With Stroke-Like Symptoms: A Rare Complication Of Mastoiditis., Shivaan C. Oomrigar, Raina K. Patel, Robert P. Mas, Jose C. Fernandez, Daniel I. Zapata

HPD Articles

Pneumocephalus is defined as the presence of gas or air in the intracranial space and typically arises as a result of neurotrauma. Clinically, pneumocephalus most often presents asymptomatically but may cause headache, nausea, vomiting, and confusion. Pneumocephalus arising from mastoiditis is an unforeseen complication with only a handful of cases reported. We report a case of an elderly male who presented with stroke-like symptoms in the setting of erosive mastoiditis with pneumocephalus.

Paravertebral Abscess Secondary To Vertebral Osteomyelitis In An Intravenous Drug User., Marianne Cortes, Taylor Mazzei, Anuj Khanna, Kira Fenton, Cristina Savu

HPD Articles

Hematogenous pyogenic vertebral osteomyelitis (VO) is a rare and often fatal complication of osteomyelitis that can affect individuals with underlying medical conditions, hospital-acquired infections, and intravenous (IV) drug abuse. Pyogenic vertebral osteomyelitis can present with generalized back pain, pyrexia, motor weakness, and neurologic deficits. The enigmatic presentation of this condition often results in delays in diagnosis and an increase in mortality. This case report aims to bring awareness to complications of hematogenous pyogenic vertebral osteomyelitis as well as highlight the need for further studies in order to establish standardized treatment. In our report, we depict a case of complicated pyogenic …

Alpl-1 Is A Target For Chimeric Antigen Receptor Therapy In Osteosarcoma., Nadia Mensali, Hakan Köksal, Sandy Joaquina, Patrik Wernhoff, Nicholas P. Casey, Paola Romecin, Carla Panisello, René Rodriguez, Lene Vimeux, Asta Juzeniene, Marit R. Myhre, Anne Fåne, Carolina Castilla Ramírez, Solrun Melkorka Maggadottir, Adil Doganay Duru, Anna-Maria Georgoudaki, Iwona Grad, Andrés Daniel Maturana, Gustav Gaudernack, Gunnar Kvalheim, Angel M. Carcaboso, Enrique De Alava, Emmanuel Donnadieu, Øyvind S. Bruland, Pablo Menendez, Else Marit Inderberg, Sébastien Wälchli

HPD Articles

Osteosarcoma (OS) remains a dismal malignancy in children and young adults, with poor outcome for metastatic and recurrent disease. Immunotherapies in OS are not as promising as in some other cancer types due to intra-tumor heterogeneity and considerable off-target expression of the potentially targetable proteins. Here we show that chimeric antigen receptor (CAR) T cells could successfully target an isoform of alkaline phosphatase, ALPL-1, which is highly and specifically expressed in primary and metastatic OS. The target recognition element of the second-generation CAR construct is based on two antibodies, previously shown to react against OS. T cells transduced with these …

Examining Movement-Specific Reinvestment And The Yips In Professional Baseball, Lazaro Gutierrez Mba, Ma, Phd, Pradeep R. Vanguri Phd, Lat, Atc

Journal for Sports Neuroscience

The sudden inability of a professional baseball player to throw the baseball accurately, a condition known as the “yips”, is considered a motor movement disruption. Movement-specific reinvestment, including movement self-consciousness (MS-C) and conscious motor processing (CMP), explains the disruption of well-learned motor movements in different performance domains such as throwing. The purpose of this quantitative, causal-comparative study is to examine movement-specific reinvestment level differences between self-reported yips-afflicted and non-afflicted professional baseball players in the United States as measured by the Movement Specific Reinvestment Scale (MSRS). A total of 130 professional baseball players (65 yips-afflicted and 65 non-afflicted) participated in the …

Community Awareness Of Youth Sport Related Concussion: A Neuropsychological Perspective, Ryan D. Bennett, Claire Stafford, Shanna K. Williams, Vijay Bajnath, Chris Burley, Alison Datoc, Alexis Hartman

Journal for Sports Neuroscience

There continues to be growing public awareness regarding concussions and the detrimental effects sustaining such an injury can have on one’s life. Of increased importance is the understanding of how concussions impact children and adolescents, particularly as a result of sport engagements. Contact sports involving youth account for 41% of the concussions seen in emergency departments (Waltzman et al., 2020). Of note, hospital estimates tend to underrepresent the total number of sport-related concussions as they do not factor patients treated in a community setting (Bazarian et al., 2020). In consideration of this public health epidemic, there is a current projection …

Lessons Learnt By An Experienced Clinician-Novice Researcher Throughout The Process Of Qualitative Research Interviewing, Heidi Lavis, Paulette Van Vliet, Meredith Tavener

The Qualitative Report

Within occupational therapy, the complex process of transitioning from clinician to clinician-researcher often presents challenges demanding critical contemplation. Methodological issues and ethical challenges can arise throughout the emergent transition into role duality, potentially impacting upon novice clinician-researcher development, influencing research processes and quality. As part of the Task-AT Home qualitative study, a reflexive critique of interview processes, guided by the reflection-on-action rubric and a typology of catalysts for dual-role experiences was conducted. The reflective critique identified commonalities and differences between clinical and research interviewing. Additionally, through three exemplars of experience, the critique provided insights into how clinical reasoning processes were …

Musculoskeletal Injury In American Football: A Bibliometric Analysis Of The Most Cited Articles., Sohil S. Desai, Craig S. Dent, Dany B. El-Najjar, Hasani W. Swindell, Charles A. Popkin

HPD Articles

BACKGROUND: Textbook knowledge and clinical dogma are often insufficient for effective evidence-based decision making when treating musculoskeletal injuries in American football players, given the variability in presentation and outcomes across different sports and different levels of competition. Key evidence can be drawn directly from high-quality published articles to make the appropriate decisions and recommendations for each athlete's unique situation.

PURPOSE: To identify and analyze the 50 most cited articles related to football-related musculoskeletal injury to provide an efficient tool in the arsenal of trainees, researchers, and evidence-based practitioners alike.

STUDY DESIGN: Cross-sectional study.

METHODS: The ISI Web of Science and …

Nanoparticle Approaches For The Renin-Angiotensin System, Sajini D. Hettiarachchi, Young M. Kwon, Yadollah Omidi, Robert C. Speth

HPD Articles

The renin-angiotensin system (RAS) is a hormonal cascade that contributes to several disorders: systemic hypertension, heart failure, kidney disease, and neurodegenerative disease. Activation of the RAS can promote inflammation and fibrosis. Drugs that target the RAS can be classified into 3 categories, AT1 angiotensin receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, and renin inhibitors. The therapeutic efficacy of current RAS-inhibiting drugs is limited by poor penetration across the blood-brain barrier, low bioavailability, and to some extent, short half-lives. Nanoparticle-mediated drug delivery systems (DDSs) are possible emerging alternatives to overcome such limitations. Nanoparticles are ideally 1-100 nm in size and are …

Nicus In The Us: Levels Of Acuity, Number Of Beds, And Relationships To Population Factors., Roberta Pineda, Kati Knudsen, Courtney C. Breault, Elizabeth E. Rogers, Wendy J. Mack, Alicia Fernandez-Fernandez

HPD Articles

OBJECTIVE: To 1) define the number and characteristics of NICUs in the United States (US) and 2) identify hospital and population characteristics related to US NICUs.

STUDY DESIGN: Cohort study of US NICUs.

RESULTS: There were 1424 NICUs identified in the US. Higher number of NICU beds was positively associated with higher NICU level (p < 0.0001). Higher acuity level and number of NICU beds related to being in a children's hospital (p < 0.0001;p < 0.0001), part of an academic center (p = 0.006;p = 0.001), and in a state with Certificate of Need legislation (p = 0.023;p = 0.046). Higher acuity level related to higher population density (p < 0.0001), and higher number of beds related to increasing proportions of minorities in the population up until 50% minorities. There was also significant variation in NICU level by region.

CONCLUSIONS: This study contributes new knowledge by describing an updated registry of NICUs in the US in 2021 that can be used for comparisons and benchmarking.

Psychometric Properties Of The Suicide Behaviors Questionnaire-Revised (Sbq-R) In American Sign Language, Jared A. Embree, Amanda M. Hinson-Enslin, Kathy Taylor, Josephine Wilson

JADARA

Limited research has focused on the risk of suicide within the deaf community, and no published studies to date report SBQ-R scores in deaf populations. The purpose of this study was to adapt the Suicide Behaviors Questionnaire-Revised into American Sign Language (SBQ-R-ASL). After the translation protocol was completed, the SBQ-R-ASL was field-tested with 340 deaf individuals in a national sample. Data analysis indicated satisfactory validity and internal consistency, and a Principal Components Analysis resulted in one factor. Field-test data revealed a mean SBQ-R-ASL score of 8.76, which is above published cutoff scores for suicide risk. These findings demonstrate a crucial …

Deaf Adults’ View Of Having Speech Language Therapy In Early Schooling, Ashley Greene, Diane Clark, G. Marissa Ramos, Caroline K. Koo, Megan B. Wimberly, Danielle Goyette

JADARA

Speech therapy and interactions with Speech Language Pathologists (SLPs) during early adolescence is a common experience of many Deaf individuals. The decision to attend speech therapy is typically made by their hearing parents in conjunction with medical and educational professionals who hold the view that deaf children need to fit into the hearing world (Harmon, 2013). With the American Speech-Language-Hearing Association (ASHA) showing that the majority of currently licensed SLPs work in school settings (ASHA, 2018) coupled with the fact that the majority of deaf children receive some speech therapy in their early schooling years, the team wanted to know …

Food Insecurity Among Deaf And Hard Of Hearing: A Scoping Review, Rylea Saunders, Laportia Jackson, Julia Vandermolen

JADARA

The authors employed a scoping review to examine peer-reviewed journal articles published between 2017 and 2020 focusing on the relationship between food insecurity among deaf and hard of hearing (DHOH) populations and language barriers using American Sign Language (ASL). Four databases yielded 257 peer-reviewed articles during the initial search. Four peer-reviewed articles were included in the review to explore the relationship between food insecurity among DHOH populations and language barriers using ASL. Multiple contributing factors create a food-insecure individual. Results indicate that income level, mental health status, and caregiver communication are all predictors of food security for DHOH. One of …

Flesh Fly Maggot-Infected Abscess In A Burn Victim Patient In The United States Without A History Of International Travel: A Case Report., Andy Aleman Espino, Erik Aleman Espino, Claudia Aleman Oliva, Gustavo Huaman, Ricardo Castrellon

HPD Articles

This case report describes an uncommon occurrence of myiasis, specifically a maggot-infected abscess, in a patient with reduced skin sensitivity resulting from severe burns. Myiasis is the infestation of live animal tissue by fly larvae, and while it is primarily associated with tropical and subtropical regions, cases acquired within the United States are rare. The presented case involves a 70-year-old male who arrived at the emergency department with an intensely painful, non-healing wound in the left elbow. Upon examination, the wound was found to be infested with numerous live maggots, and subsequent investigations revealed the larvae to be of the …

Leptomeningeal Myelomatosis: An Unusual Presentation Of Multiple Myeloma, Vasu Malhotra, Vikas Malhotra, Kenneth Shain

HPD Articles

Multiple myeloma (MM) is characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. Although neurological complications are commonly seen in MM, they most frequently occur due to spinal cord compression by bony lesions, paraprotein-related neuropathy, hypercalcemia, hyper viscosity, or amyloidosis. Less than 1% of patients with MM present with a leptomeningeal disease. We present a case of a leptomeningeal myeloma in a 61-year-old woman with known relapsed MM who presented with headaches and dysphagia. We present this case to alert clinicians to keep a high index of suspicion in cases of Multiple Myeloma presenting with non-specific neurological …

Exploring The Potential Of Nanotechnology In Pediatric Healthcare: Advances, Challenges, And Future Directions., Hossein Omidian, Kwadwo Mfoafo

HPD Articles

The utilization of nanotechnology has brought about notable advancements in the field of pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and tissue engineering. Nanotechnology involves the manipulation of materials at the nanoscale, resulting in improved drug effectiveness and decreased toxicity. Numerous nanosystems, including nanoparticles, nanocapsules, and nanotubes, have been explored for their therapeutic potential in addressing pediatric diseases such as HIV, leukemia, and neuroblastoma. Nanotechnology has also shown promise in enhancing disease diagnosis accuracy, drug availability, and overcoming the blood-brain barrier obstacle in treating medulloblastoma. It is important to acknowledge that while nanotechnology offers significant opportunities, there …

The Effect Of Doulas On Maternal And Birth Outcomes: A Scoping Review., Alexandria Sobczak, Lauren Taylor, Sydney Solomon, Jodi Ho, Scotland Kemper, Brandon Phillips, Kailey Jacobson, Courteney Castellano, Ashley Ring, Brianna Castellano, Robin J. Jacobs

HPD Articles

A source of support during birth could be the solution to negative outcomes for the mother and her baby. To improve the birthing experience and increase positive birthing outcomes, sources of support during pregnancy should be evaluated and understood. The goal of this review was to synthesize the existing literature on how doulas might improve birth outcomes. This scoping review also aimed to shed light on the positive impact emotional support during childbirth can have on the health and well-being of mother and child. PubMed and EBSCOhost were used to identify articles using the search words with Boolean operators "doulas" …

Exploring The Legal Implications Of Benign Prostatic Hyperplasia Surgeries In The United States: A Comprehensive Analysis Of Two Decades Of Lawsuits., Joao Porto, Maria Camila Suarez Arbelaez, Mohamadhusni Zarli, Mariam Ahumada, Sanjaya Swain, Robert Marcovich, Hemendra N. Shah

HPD Articles

INTRODUCTION AND OBJECTIVE: The United States (US) currently faces a medical malpractice crisis, and a survey done in 2006 informed that 63% of urologists faced an average of 2.1 medical malpractice lawsuits. Surgery for benign prostatic hyperplasia (BPH) is performed by 95% of US urologists. Hence, we postulated that these procedures might be responsible for a substantial number of medical malpractice lawsuits. We examined claims related to BPH surgery in various US courts.

MATERIALS AND METHODS: Data were collected from Westlaw and LexisNexis databases using the keywords "benign prostatic hyperplasia," "enlarged prostate," "surgery," and "malpractice" to search for cases from …