Medicine and Health Sciences Commons^™

Direct Phenotypic Screening In Mice: Identification Of Individual, Novel Antinociceptive Compounds From A Library Of 734 821 Pyrrolidine Bis-Piperazines, Richard A. Houghten, Michelle L. Ganno, Jay P. Mclaughlin, Colette T. Dooley, Shainnel O. Eans Torrey Pines Institute For Molecular Studies, Radleigh Santos, Travis Lavoi, Adel Nefzi, Greg Welmaker, Marc A. Giulianotti, Lawrence Toll

Mathematics Faculty Articles

The hypothesis in the current study is that the simultaneous direct in vivo testing of thousands to millions of systematically arranged mixture-based libraries will facilitate the identification of enhanced individual compounds. Individual compounds identified from such libraries may have increased specificity and decreased side effects early in the discovery phase. Testing began by screening ten diverse scaffolds as single mixtures (ranging from 17 340 to 4 879 681 compounds) for analgesia directly in the mouse tail withdrawal model. The “all X” mixture representing the library TPI-1954 was found to produce significant antinociception and lacked respiratory depression and hyperlocomotor effects using …

Assessing Orthodontic-Bracket Impacts On Lip Profile At Bonding And Debonding Stages, Martin Trockel

Student Theses, Dissertations and Capstones

Introduction: One factor that contributes greatly to the lower face appearance and orthodontists have the ability to affect is lip profile. Clinical assessment of the lip profile is an important element in the decision of orthodontic treatment planning and in the evaluation of treatment progress and outcome. Three known factors influence the lip profile; the lip thickness, the underlying bone, and the tooth position. The positions and inclinations of the anterior teeth can affect the lip position, but it is unclear whether orthodontic brackets bonded to the labial surface of anterior teeth move the lip position and thereafter change the …

Effects Of Sodium Hypochlorite On Enamel Composition, Sonni Pellillo

Student Theses, Dissertations and Capstones

The purpose of this study was to evaluate the effects of sodium hypochlorite on the organic and inorganic composition of enamel. Background: With the advent of enamel bonding for orthodontic appliances in the late 1970s, it has been shown that traditional phosphoric acid etching affects the inorganic portion of the enamel.1, 2 In an attempt to enhance the acid etching pattern and, furthermore, the bond strength, additional pretreatment techniques that target the organic components of the enamel biofilm have been proposed. One such method is the non-invasive enamel pretreatment with 5.25% sodium hypochlorite (NaOCl) prior to phosphoric acid etching.3, 4 …

Evaluation Of Frictional Forces Between Brackets Of Different Types At Various Angulations And An Arch Wire: With And Without Pulsating Vibration, Benjamin M. Christman

Student Theses, Dissertations and Capstones

Objective: The objective of this study was to determine the effect of pulsating vibration on the sliding resistance between orthodontic brackets and stainless steel wires. Brackets were placed at two different angulations (0° and 5°) to simulate leveling of a tipped tooth during tooth movement. Pulsating vibration was delivered via the AcceleDent device.

Background: Friction is defined as a force that retards or resists the relative motion of two objects in contact, and its direction is tangential to the common boundary of the two surfaces in contact. This has been of interest to the orthodontist since the mid-20th century. Since …

Humeral Retrotorsion In Developing Children And Its Relationship To Throwing Sports, Elliot M. Greenberg

Department of Physical Therapy Student Theses, Dissertations and Capstones

Background: Baseball players exhibit a more posteriorly oriented humeral head or humeral retrotorsion (HRT) in the dominant arm, likely representing an adaptive response to the stress of throwing. This adaptation is thought to occur while skeletally immature, however there is limited research detailing how throwing while young influences the development HRT. In addition, it is currently unclear how this changing osseous orientation influences shoulder motion within young athletes. Purpose: To determine the influence of throwing and age on the development of asymmetry in HRT and shoulder range of motion (ROM); and analyze the relationship between HRT and ROM. Study Design: …

Investigating The Role Of The Host Multidrug Resistance Associated Protein Transporter Family In Burkholderia Cepacia Complex Pathogenicity Using A Caenorhabditis Elegans Infection Model, Pietro Tedesco, Marco Visone, Ermenegilda Parrilli, Maria Luisa Tutino, Elena Perrin, Isabel Maida, Renato Fani, Francesco Ballestriero, Radleigh Santos, Clemencia Pinilla, Elia Di Schiavi, George Tegos, Donatella De Pascale

Mathematics Faculty Articles

This study investigated the relationship between host efflux system of the non-vertebrate nematode Caenorhabditis elegans and Burkholderia cepacia complex (Bcc) strain virulence. This is the first comprehensive effort to profile host-transporters within the context of Bcc infection. With this aim, two different toxicity tests were performed: a slow killing assay that monitors mortality of the host by intestinal colonization and a fast killing assay that assesses production of toxins. A Virulence Ranking scheme was defined, that expressed the toxicity of the Bcc panel members, based on the percentage of surviving worms. According to this ranking the 18 Bcc strains were …

The Genome Russia Project: Closing The Largest Remaining Omission On The World Genome Map, T. K. Oleksyk, Vladimir Brukhin, Stephen J. O'Brien

Biology Faculty Articles

We are witnessing the great era of genome exploration of the world, as genetic variation in people is being detailed across multiple varied world populations in an effort unprecedented since the first human genome sequence appeared in 2001. However, these efforts have yet to produce a comprehensive mapping of humankind, because important regions of modern human civilization remain unexplored. The Genome Russia Project promises to fill one of the largest gaps, the expansive regions across the Russian Federation, informing not just medical genomics of the territories, but also the migration settlements of historic and pre-historic Eurasian peoples.

Color Of Porcelain Veneer After Final Cementation In Comparison To Try-In Paste And Permanent Cement: An In Vitro Study, Abdulelah Aldahlawi

Student Theses, Dissertations and Capstones

Objectives: To evaluate and compare the color of porcelain veneers with try-in paste in relation to porcelain veneers with permanent cement. Also, to evaluate and compare combinations of three different shades and thicknesses of porcelain veneers and three cement shades before and after final cementation. Additionally, to evaluate and compare the color of porcelain veneers with cured permanent cement before and after aging. Background: Porcelain veneers and ceramic restorations have become one of the most popular approaches in the anterior area due to their natural appearance and esthetics. However, more conservative approaches have led to thinner restorations with increased translucency. …

Ex Vivo Effects Of An Orthodontic-Specific Bleaching System On Tooth Color And Existing Bracket Bonding, Kirk James Bean

Student Theses, Dissertations and Capstones

Objective: The purpose of this ex vivo study was to assess the changes in tooth color and existing orthodontic bracket bonding when exposed to a bleaching agent. Methods: 120 freshly extracted human premolars were equally divided into 4 groups: a negative-control group, a positive-control bleaching group, a bracket-bonded group, and a bracket bonded-bleached group. The bleaching protocol was carried out as recommended by the manufacturer of Opalescence Go® – 30 minutes each day for 10 consecutive days. The color value of each tooth was measured daily by spectrophotometry for the negative-control group and the positive-control bleaching group in 6 different …

Adjunctive Appliance Wear And Gender Affect Patients' Oral Health-Related Quality Of Life During The Late Stage Of Orthodontic Treatment In Adolescents, Monica Dinh

Student Theses, Dissertations and Capstones

Objective: This study was conducted to determine how oral health-related quality of life (OHQoL) changes during the late stage of comprehensive fixed orthodontic treatment in adolescents and what factors may be involved. Background: Completion of orthodontic treatment has been shown to improve patients’ OHQoL due to the changes in esthetics, function and emotional well-being. The levels of OHQoL fluctuate throughout treatment where an initial decrease within the first 6 months occurs followed by an improvement towards patients’ pre-treatment levels. At 18 months of fixed orthodontic treatment, the level is unclear. The aims of this study were to clarify the changes …

Medical Education Digest, Vol. 17 No. 6 (November-December 2015), Nova Southeastern University

Medical Education Digest

No abstract provided.

Living The Implicit Curriculum, Leaving A Legacy, Ricardo Carrasco

OCCUPATION: A Medium of Inquiry about Health through Occupation

This paper introduces the inaugural issue of OCCUPATION: A Medium of Inquiry for Stu dents, Faculty & Other Practitioners Advocating for Health through Occupational Studies. The paper asserts that implicit or hidden curriculum partners with the implicit curriculum, especially in health care education that promotes the students’ journey that employs doing, in the transfor - mative process in being and becoming entry-level practitioners.

November 2015 Issue, Occupation: A Medium Of Inquiry For Students, Faculty & Other Practitioners Advocating For Health Through Occupational Studies

OCCUPATION: A Medium of Inquiry about Health through Occupation

No abstract provided.

Global Issue Of Clean Water As It Impacts Occupation, Hillary E. W. Anderson

OCCUPATION: A Medium of Inquiry about Health through Occupation

The purpose of this position paper is to explore the global impact of the lack or limited access to clean water on occupational engagement. The majority of the developed world has access to clean water, however, an alarming number of individuals do not have access to s governs, and impedes occupational engagement of millions globally. In order to enforce occupational justice, afforded from clean water, on a global scale, a fueling passion for change must be experienced by a collaborative force in a focused effort. Ultimately, access to clean water should be a basic human right propagated to all.

The Occupational Benefits Of Children Farming, Ellie Edrissi

OCCUPATION: A Medium of Inquiry about Health through Occupation

This paper analyses the positive outcomes of youth responsibilities, routines, autonomy, youth programs and scholarships, cultural identity, educational and life experiences through the occupation of farming during seasonal and/or after school hours. The multidimensional context of children willingly working in the agricultural industry allows positive psychological, economical, and cultural experiences while building a stronger family unity. The occupation of farming allows youth participation with the environment, social skills, inter-generational transfer of skills, and increased confidence for future aspirations as they mature to adulthood.

Societal Statement On The Role Of Occupational Therapy With Survivors Of Human Sex Trafficking In The United States, Chelsea Bryant, Lillian Freeman, Meghan Granata, Annie He, Hillarie Hough, Shree Patel, Ashley Stedman, Stephanie Silvia, My-Lynn Tran

OCCUPATION: A Medium of Inquiry about Health through Occupation

As part of a specialized course, OTD 8340 Wellness and Health Promotion in Occupational Therapy, students from the Nova Southeastern University Entry Level Doctor of Occupational Therapy program, drafted a Societal Statement on the role of occupational therapy with survivors of human sex trafficking in the United States. The students explored the issue of domestic human sex trafficking from an occupational perspective, under the guidance of their professor, Mirtha Montejo Whaley, PhD, OTR/L. As of the publication of this journal, the document is under review by the American Occupational Therapy Association (AOTA)

Access Denied: Barriers For Unauthorized Immigrants Pursuing The American Dream, Kristin Mcmillen

OCCUPATION: A Medium of Inquiry about Health through Occupation

Millions of immigrants from all around the world are living in the United States without legal authorization. Most have come in search of a better life for themselves or their children, with the belief that through enough hard work, they can achieve the “American Dream.” However, upon arrival, many unauthorized immigrants face cultural, economic, and political barriers that limit their opportunities for community participation and lead many individuals to live their lives in fear. This paper aims to: (a) explore the barriers encountered by unauthorized immigrants in the United States; (b) consider the occupational significance of these barriers; and (c) …

Clinical Supervision In Allied Health In Australia: A Model Of Allied Health Clinical Supervision Based On Practitioner Experience, Sue Fitzpatrick, Megan Smith, Clare Wilding

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this manuscript is to identify key elements of allied health clinical supervision based on allied health practitioner’s experiences. Method: This study was conducted with qualitative methodology, including content analysis, and draws on hermeneutic interpretation of texts. Data were collected through an online survey in an Australian health service and subsequent focus groups. Results: Findings revealed four key dimensions including accessibility of regular clinical supervision, relationships between the supervisor and supervisee, clarity about the purpose, and roles and a focus on meeting the supervisee’s needs; these dimensions were central to the allied health practitioner’s …

Analysis Of Speech-Language Pathology Graduate Students' Experience With Thickened Liquids, Mary Gorham-Rowan, Jade Coston

Internet Journal of Allied Health Sciences and Practice

Purpose: Thickened liquids are frequently recommended for patients with dysphagia to minimize aspiration. When discussing the use of thickened liquids with graduate students in Communication Sciences & Disorders (CSD), it is beneficial to discuss the potential effect(s) of this dietary recommendation. Graduate level preparation involving first-hand experience with thickened liquids may help future speech-language pathologists (SLPs) develop a more complete understanding of the effects of diet modification. The purpose of the current study was to examine the reactions of graduate students in CSD to a brief period of thickened liquid use as an experiential learning activity. Methods: Sixty-eight graduate students …

A Comparison Of Static Stretching Versus Combined Static And Ballistic Stretching In Active Knee Range Of Motion, Nathan R. Blackhurst, James C. Peterson, Valerie W. Herzog, Ericka P. Zimmerman

Internet Journal of Allied Health Sciences and Practice

Background: There is continued controversy related to flexibility gains from different stretching protocols and within single protocols. Stretching methods include static, ballistic, dynamic, and proprioceptive neuromuscular facilitation (PNF). A combination of stretching methods may be an improved way to increase active knee range of motion (ROM). This study evaluated a single program formulated with static and ballistic components. Objective: To compare active knee ROM following stretching programs which either included combined static and ballistic stretching (CSBS) or static stretching (SS) alone. It was hypothesized that CSBS would show a greater increase in active knee ROM than SS. Setting …

Faculty And Student Perceptions Of A Physical Therapy Professional Behavior Mentoring Program, Ethel Frese, Cheryl Cavallo, Kelly Hawthorne, Ginge Kettenback, Barbara Yemm

Internet Journal of Allied Health Sciences and Practice

Purpose: Mentoring is a process and a relationship between a novice and an expert that fosters intellectual, personal, and professional growth. The purposes and scope of this article are to describe 1) the structured professional development component of a comprehensive mentoring program for students in a physical therapy program; and 2) the perceptions of faculty and students regarding this mentoring program. Method: Faculty and students completed electronic questionnaires developed specifically for each group. Results: Return rate was 54.50% (N=286) for physical therapist students and 100% (N=18) for physical therapy faculty. Student positive ratings regarding the mentoring program exceeded 89.00%. Additionally, …

Training Hospital Readiness In Speech-Language Pathology Students Through Simulation, Anna Miles, Selena Donaldson, Philippa Friary

Internet Journal of Allied Health Sciences and Practice

Simulated learning environments allow students to develop technical and clinical decision-making skills in a safe and realistic setting. The aim of this study was to evaluate speech-language pathology students’ perception of hospital readiness following a one-day simulation-based training day on swallowing management. Nineteen students attended the training day. Training included part-task skill learning and immersive simulated scenarios. Students were asked to complete course evaluation forms and participated in focus groups immediately after the day. Seven students participated in a further focus group after a five-week hospital placement within a month of the training day. Four students participated in a focus …

Physical Therapy Clinical Instructor Self-Reported Evidence-Based Practice Use, Debra Bierwas, Joan Leafman, Lisa Wallace, Donald Shaw, Steven Fehrer

Internet Journal of Allied Health Sciences and Practice

Introduction: Evidence-based practice is a required component of student physical therapist education. Practice applying the five steps of evidence-based practice to patient care (formulate question, retrieve evidence, appraise evidence, integrate evidence, evaluate outcomes), most effectively performed during clinical education, must occur for students to become proficient. Clinical instructor use of evidence-based practice is essential to assure that student physical therapist practice occurs during clinical education. Purpose: The purpose of this study was to assess self-reported evidence-based practice use by physical therapy clinical instructors and examine whether an association exists between professional characteristics and evidence-based practice use. Methods: This study …

Healthcare Student Immunizations: An Overview, Douglas Gardenhire

Internet Journal of Allied Health Sciences and Practice

All clinical healthcare programs (CHP) in the United States require documentation of many types of immunizations and health information. The key for CHP personnel is to determine if immunization and health information is valid or if immunity exists. Documentation alone does not guarantee a student will be protected. This document will review common immunization and health information collected by many CHP and provide recommendations that programs may consider when adopting or changing polices on student immunization and health information.

A Description Of Current Curricular Design Models Used In Physical Therapy Clinical Education And Their Relationship To Pass Rates On The National Physical Therapy Examination, Chalee Engelhard, Christine Mccallum

Internet Journal of Allied Health Sciences and Practice

Purpose. The purpose of this study was to develop descriptions and identify commonalities of current clinical education models used in physical therapy programs; then, using this information, to examine differences in first-time and ultimate pass rates among the derived formula from Commission on Accreditation in Physical Therapy Education (CAPTE) accredited programs in 2011-2013. Methods. This mixed methods study captured qualitative and quantitative data from the 204 PT programs located in the United States and Puerto Rico from 2011 to 2013. The data were coded into 11 different clinical education models which represented all programs. The models were then linked to …

Church Pew Exercise Integrated With Conventional Physical Therapy Following Total Knee Arthroplasty (Tka): Case Report, Randell Gonzales, Jerome Danoff

Internet Journal of Allied Health Sciences and Practice

Background and Purpose: Physical therapy treatment following Total knee Arthroplasty (TKA) consists of a combination of strengthening and range of motion exercises. The exercise technique, church pew exercise (CPE), has been proposed to enhance quadriceps facilitation and improve function. This is a technique that has the patient standing and rocking forward/back. The backward motion is arrested by engagement of the upper calf against a solid object, creating a sudden flexion torque at the knee and a sudden extension torque at the hip. The combination of CPE with standard physical therapy is claimed to provide better quadriceps control and faster walking …

Perspectives Volume 3: Number 2, Fall 2015, College Of Health Care Sciences

Perspectives

No abstract provided.

The Lli Chronicle Volume 6 Number 3, Nova Southeastern University

Lifelong Learning Institute Newsletters

No abstract provided.

Lasting Impressions, Fall 2015, College Of Dental Medicine

Newsletters

No abstract provided.

Selective C1 Lesioning Slightly Decreases Angiotensin Ii Type I Receptor Expression In The Rat Rostral Ventrolateral Medulla (Rvlm)., Erick A Bourassa, Kristen A Stedenfeld, Alan F Sved, Robert Charles Speth

Faculty Articles

Cardiovascular homeostasis is regulated in large part by the rostral ventrolateral medulla (RVLM) in mammals. Projections from the RVLM to the intermediolateral column of the thoracolumbar spinal cord innervate preganglionic neurons of the sympathetic nervous system causing elevation of blood pressure and heart rate. A large proportion, but not all, of the neurons in the RVLM contain the enzymes necessary for the production of epinephrine and are identified as the C1 cell group. Angiotensin II (Ang II) activates the RVLM acting upon AT1 receptors. To assess the proportion of AT1 receptors that are located on C1 neurons in the rat …