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Articles 1 - 26 of 26
Full-Text Articles in Medicine and Health Sciences
Feline Immunodeficiency Virus Integration In B-Cell Lymphoma Identifies A Candidate Tumor Suppressor Gene On Human Chromosome 15q151, Julia Beatty, Anne Terry, Julie Macdonald, Elizabeth Gault, Stanley Cevario, Stephen J. O'Brien, Ewan Cameron, James C. Neil
Feline Immunodeficiency Virus Integration In B-Cell Lymphoma Identifies A Candidate Tumor Suppressor Gene On Human Chromosome 15q151, Julia Beatty, Anne Terry, Julie Macdonald, Elizabeth Gault, Stanley Cevario, Stephen J. O'Brien, Ewan Cameron, James C. Neil
Biology Faculty Articles
Infection with immunosuppressive lentiviruses is associated with increased cancer risk,but most studies have implicated indirect mechanisms as the tumor cells generally lack integrated viral sequences.An exception wasfound in a B-cell lymphoma (Q254) where the tumor cells contained a single integrated feline immunodeficiency virus genome. Additional analysis now indicates that feline immunodeficiency virus integration in lymphoma Q254 resulted in promoter insertion and truncation of a conserved gene on feline chromosome B3, whereas the unaffected allele of the gene appeared to be transcriptionally down-regulated. The orthologous human gene (FLJ12973), is expressed ubiquitously and encodes a WD-repeat protein with structural similarity …
Medical Education Digest, Vol. 4 No. 6 (November 15, 2002), Nova Southeastern University
Medical Education Digest, Vol. 4 No. 6 (November 15, 2002), Nova Southeastern University
Medical Education Digest
No abstract provided.
Com Outlook Fall 2002, College Of Osteopathic Medicine
Com Outlook Fall 2002, College Of Osteopathic Medicine
COM Outlook
No abstract provided.
Ang Ii At(1) And At(2) Receptors In Developing Kidney Of Normal Microswine, Susan P. Bagby, Linda S. Lebard, Zaiming Luo, Bryan E. Ogden, Christopher Corless, Elizabeth D. Mcpherson, Robert C. Speth
Ang Ii At(1) And At(2) Receptors In Developing Kidney Of Normal Microswine, Susan P. Bagby, Linda S. Lebard, Zaiming Luo, Bryan E. Ogden, Christopher Corless, Elizabeth D. Mcpherson, Robert C. Speth
HPD Articles
To identify an appropriate model of human renin-angiotensin system (RAS) involvement in fetal origins of adult disease, we quantitated renal ANG II AT(1) and AT(2) receptors (AT1R and AT2R, respectively) in fetal (90-day gestation, n = 14), neonatal (3-wk, n = 5), and adult (6-mo, n = 8) microswine by autoradiography ((125)I-labeled [Sar(1)Ile(8)]ANG II+cold CGP-42112 for AT1R, (125)I-CGP-42112 for AT2R) and by whole kidney radioligand binding. The developmental pattern of renal AT1R in microswine, like many species, exhibited a 10-fold increase postnatally (P < 0.001), with maximal postnatal density in glomeruli and lower density AT1R in extraglomerular cortical and outer medullary sites. With aging, postnatal AT1R glomerular profiles increased in size (P < 0.001) and fractional area occupied (P < 0.04), with no change in the number per unit area. Cortical levels of AT2R by autoradiography fell with age from congruent with 5,000 fmol/g in fetal kidneys to congruent with 60 and 20% of fetal levels in neonatal and adult cortex, respectively (P < 0.0001). The pattern of AT2R binding in postnatal pig kidney mimicked that described in human and simian, but not rodent, species: dense AT2R confined to discrete cortical structures, including pre- and juxtaglomerular, but not intraglomerular, vasculature. Our results provide a quantitative assessment of ANG II receptors in developing pig kidney and document the concordance of pigs and primates in developmental regulation of renal AT1R and AT2R.
Medical Education Digest, Vol. 4 No. 5 (September 15, 2002), Nova Southeastern University
Medical Education Digest, Vol. 4 No. 5 (September 15, 2002), Nova Southeastern University
Medical Education Digest
No abstract provided.
College Of Optometry Course Of Study 2002, Nova Southeastern University
College Of Optometry Course Of Study 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Medical Education Digest, Vol. 4 No. 4 (July 15, 2002), Nova Southeastern University
Medical Education Digest, Vol. 4 No. 4 (July 15, 2002), Nova Southeastern University
Medical Education Digest
No abstract provided.
Com Outlook Summer 2002, College Of Osteopathic Medicine
Com Outlook Summer 2002, College Of Osteopathic Medicine
COM Outlook
No abstract provided.
College Of Optometry Student Handbook July 2002, Nova Southeastern University
College Of Optometry Student Handbook July 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Allied Health Student Handbook July 2002, Nova Southeastern University
College Of Allied Health Student Handbook July 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Medical Education Digest, Vol. 4 No. 3 (May 15, 2002), Nova Southeastern University
Medical Education Digest, Vol. 4 No. 3 (May 15, 2002), Nova Southeastern University
Medical Education Digest
No abstract provided.
Hla-Cw*04 And Hepatitis C Virus Persistence, Chloe L. Thio, Xiaojiang Gao, James J. Goedert, David Vlahov, Kenrad E. Nelson, Margaret Hilgartner, Stephen J. O'Brien, Peter Karacki, Jacquie Astemborski, Mary Carrington, David L. Thomas
Hla-Cw*04 And Hepatitis C Virus Persistence, Chloe L. Thio, Xiaojiang Gao, James J. Goedert, David Vlahov, Kenrad E. Nelson, Margaret Hilgartner, Stephen J. O'Brien, Peter Karacki, Jacquie Astemborski, Mary Carrington, David L. Thomas
Biology Faculty Articles
In studies of acute hepatitis C virus (HCV) infection, the early host immune response is one of the determinants of viral persistence. The class I human leukocyte antigens (HLA), which present foreign antigen to cytolytic T cells, are integral components of this response. We hypothesized that the highly polymorphic HLA genes affect the outcome of an HCV infection. To test this hypothesis, we molecularly typed 231 persons with well-documented clearance of an HCV infection and 444 matched persistently infected persons. HLA-A*1101 (odds ratio [OR], 0.49; 95% confidence interval [95% CI], 0.27 to 0.89), HLA-B*57 (OR, 0.62; 95% CI, 0.39 to …
Com Outlook Summer 2004, College Of Osteopathic Medicine
Com Outlook Summer 2004, College Of Osteopathic Medicine
COM Outlook
No abstract provided.
Medical Education Digest, Vol. 4 No. 2 (March 15, 2002), Nova Southeastern University
Medical Education Digest, Vol. 4 No. 2 (March 15, 2002), Nova Southeastern University
Medical Education Digest
No abstract provided.
Medical Education Digest, Vol. 4 No. 1 (January 15, 2002), Nova Southeastern University
Medical Education Digest, Vol. 4 No. 1 (January 15, 2002), Nova Southeastern University
Medical Education Digest
No abstract provided.
Com Outlook Winter 2001-2002, College Of Osteopathic Medicine
Com Outlook Winter 2001-2002, College Of Osteopathic Medicine
COM Outlook
No abstract provided.
College Of Dental Medicine Student Handbook July 2002, Nova Southeastern University
College Of Dental Medicine Student Handbook July 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Health Professions Division Catalog Academic Year 2002-2003, Nova Southeastern University
Health Professions Division Catalog Academic Year 2002-2003, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Pharmacy Overview In Ponce, Puerto Rico, Nova Southeastern University
College Of Pharmacy Overview In Ponce, Puerto Rico, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Pharmacy Student Handbook July 2002, Nova Southeastern University
College Of Pharmacy Student Handbook July 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Osteopathic Medicine Student Handbook July 2002, Nova Southeastern University
College Of Osteopathic Medicine Student Handbook July 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Osteopathic Medicine Program Overview, Nova Southeastern University
College Of Osteopathic Medicine Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Occupational Therapy Program 2002, Nova Southeastern University
Occupational Therapy Program 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Optometry Program Overview, Nova Southeastern University
College Of Optometry Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Dental Medicine Overview 2002, Nova Southeastern University
College Of Dental Medicine Overview 2002, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Pharmacy Program Overview, Nova Southeastern University
College Of Pharmacy Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.