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Articles 211 - 219 of 219
Full-Text Articles in Medicine and Health Sciences
Impaired Cognitive Performance And Hippocampal Atrophy In Parkinson Disease, Demet Yildiz, Sevda Erer, Mehmet Zari̇foğlu, Bahatti̇n Hakyemez, Mustafa Bakar, Necdet Karli, Zeynep Ni̇gar Varlibaş, Fati̇h Tufan
Impaired Cognitive Performance And Hippocampal Atrophy In Parkinson Disease, Demet Yildiz, Sevda Erer, Mehmet Zari̇foğlu, Bahatti̇n Hakyemez, Mustafa Bakar, Necdet Karli, Zeynep Ni̇gar Varlibaş, Fati̇h Tufan
Turkish Journal of Medical Sciences
Background/aim: Dementia is common in Parkinson disease (PD). Since magnetic resonance imaging has been used, hippocampal atrophy has been shown in PD patients with or without dementia. In this study we sought the correlation of cognitive decline with bilateral hippocampal volume in PD patients. Materials and methods: Thirty-three patients with diagnosis of idiopathic PD and 16 healthy subjects were included in this study. PD patients were divided into two groups as normal cognitive function and mild cognitive impairment (MCI). The Mini-Mental State Examination and detailed cognitive assessment tests were performed for all patients for cognitive analyses. Depression was excluded by …
Test Your Memory-Turkish Version (Tym-Tr): Reliability And Validity Study Of A Cognitive Screening Test, İlknur Mavi̇ş, Belgi̇n Demet Özbabalik Adapinar, Çinar Yeni̇lmez, Ayşe Aydin, Engi̇n Olgun, Cengi̇z Bal
Test Your Memory-Turkish Version (Tym-Tr): Reliability And Validity Study Of A Cognitive Screening Test, İlknur Mavi̇ş, Belgi̇n Demet Özbabalik Adapinar, Çinar Yeni̇lmez, Ayşe Aydin, Engi̇n Olgun, Cengi̇z Bal
Turkish Journal of Medical Sciences
Background/aim: The test your memory (TYM) is reported to be a sensitive cognitive function assessment scale for people with dementia. The aim of the present study was to investigate the reliability and validity of an adapted Turkish version of the TYM (TYM-TR) among Turkish dementia patients. Materials and methods: The TYM-TR was given to 59 patients with dementia aged 60+ and 336 normal controls aged 23-75+. The diagnostic utility of the TYM-TR was compared with that of the mini-mental state examination (MMSE) to validate it. Results: The internal consistency of the TYM-TR was α = 0.85. The test-retest reliability was …
The Effectiveness Of Ultrasound Treatment For The Management Of Kneeosteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study, Serap Kapci Yildiz, Feyza Ünlü Özkan, İlknur Aktaş, Ayşe Duygu Şi̇lte, Meryem Yilmaz Kaysin, Naci̇ye Bi̇lgi̇n Badur
The Effectiveness Of Ultrasound Treatment For The Management Of Kneeosteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study, Serap Kapci Yildiz, Feyza Ünlü Özkan, İlknur Aktaş, Ayşe Duygu Şi̇lte, Meryem Yilmaz Kaysin, Naci̇ye Bi̇lgi̇n Badur
Turkish Journal of Medical Sciences
Background/aim: A randomized, placebo-controlled, double-blind study was designed to investigate the effectiveness of ultrasound therapy in primary knee osteoarthritis. Materials and methods: Ninety patients between 40 and 65 years of age having grade 2 and 3 bilateral knee osteoarthritis enrolled in the study were randomly assigned into 3 groups: continuous ultrasound, pulsed ultrasound, and placebo ultrasound. All patients were given a home exercise program. Patients were evaluated at baseline, at the end of the treatment, and at the second month after the treatment by a range of motion measurement, visual analog scale, Lequesne index for knee osteoarthritis, and Short Form-36 …
Investigation Of The Diagnostic Value Of Chromosome Analysis And Bacterial Artificial Chromosome-Based Array Comparative Genomic Hybridization In Prenatal Diagnosis, Hakan Savli, Seda Eren Keski̇n, Naci̇ Çi̇ne
Investigation Of The Diagnostic Value Of Chromosome Analysis And Bacterial Artificial Chromosome-Based Array Comparative Genomic Hybridization In Prenatal Diagnosis, Hakan Savli, Seda Eren Keski̇n, Naci̇ Çi̇ne
Turkish Journal of Medical Sciences
Background/aim: To investigate the diagnostic value of bacterial artificial chromosome (BAC)-based array comparative genomic hybridization (CGH) and chromosome analysis in prenatal diagnosis. Materials and methods: This study included the chromosome analysis and BAC-based array CGH analysis of 140 amniocentesis samples with prenatal diagnosis indications. Results: Karyotype analysis showed trisomy 21 in 4 patients, trisomy 18 in 5 patients, monosomy X in 1 patient, and other anomalies in 3 patients. The BAC-based array CGH analysis showed 4 patients with trisomy 21, 4 patients with trisomy 18, and 1 patient with monosomy X as a numerical chromosome anomaly, while partial duplication was …
Hypogastric Artery Ligation For Obstetrical Hemorrhage: Clinical Experiencein A Tertiary Care Center, Çağlar Yildiz, Özlem Bozoklu Akkar, Savaş Karakuş, Ali̇ Çeti̇n, Ali̇ Yanik
Hypogastric Artery Ligation For Obstetrical Hemorrhage: Clinical Experiencein A Tertiary Care Center, Çağlar Yildiz, Özlem Bozoklu Akkar, Savaş Karakuş, Ali̇ Çeti̇n, Ali̇ Yanik
Turkish Journal of Medical Sciences
Background/aim: Several authorities advocate the use of hypogastric artery ligation (HAL) in the treatment of cases of obstetrical hemorrhage related to uterine atony or placenta accreta. We assessed the morbidity and mortality of patients who underwent HAL as a component of emergency procedures to control life-threatening uterine bleeding in a tertiary-care university hospital. Materials and methods: In this retrospective study, the clinical data of 24 eligible patients who underwent HAL between 2010 and 2013 in a university hospital to prevent or control severe uterine bleeding were collected and analyzed with regard to intraoperative and postoperative findings. Results: In the study …
Workplace Physical Violence, Verbal Violence, And Mobbing Experiencedby Nurses At A University Hospital, Fatma Nur Baran Aksakal, Emi̇ne Füsun Karaşahi̇n, Asi̇ye Uğraş Di̇kmen, Emi̇ne Avci, Seçi̇l Özkan
Workplace Physical Violence, Verbal Violence, And Mobbing Experiencedby Nurses At A University Hospital, Fatma Nur Baran Aksakal, Emi̇ne Füsun Karaşahi̇n, Asi̇ye Uğraş Di̇kmen, Emi̇ne Avci, Seçi̇l Özkan
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the frequency of and risk factors for physical violence, verbal violence, and mobbing experienced by nurses in a university hospital. Materials and methods: This was a cross-sectional study conducted at Gazi University Medical Faculty Hospital. A questionnaire form recommended by the WHO and the International Labor Organization was administered through face-to-face interviews to determine the violence experienced in the past 12 months by nurses. Results: The prevalence of physical violence, verbal violence, and mobbing was 13.9%, 41.8%, and 17.1%, respectively. Working more than 40 h per week increased the risk of …
An Anatomical Study Of The Supratrochlear Foramen Of The Jining Population, Jing Li, Qinghua Mao, Wenyuan Li, Xiaoyan Li
An Anatomical Study Of The Supratrochlear Foramen Of The Jining Population, Jing Li, Qinghua Mao, Wenyuan Li, Xiaoyan Li
Turkish Journal of Medical Sciences
Background/aim: The supratrochlear foramen (STF) is an important variation in the lower end of the humerus where the septum separating the coronoid and olecranon fossa is perforated. There are no studies in the literature on the STF of the Jining population. This study will make a contribution to anatomy and anthropology by adding new data. Materials and methods: STF was studied in detail in 262 adult dried humeri of unknown sex and age. The topographical anatomy of the STF was studied, morphometric measurements were taken, and the specimens were photographed with a digital camera. Results: The prevalence of the STF …
Investigation Of The Protective Effect Of Erdosteine Against Cyclosporine-Inducedinjury In Rat Liver With Histological And Biochemical Methods, Ahmet Nacar, İhsan Karaboğa, Hamza Mali̇k Okuyan, Nebi̇hat Kaplan Sefi̇l, Emel Nacar, Sedat Motor, Seçki̇n Akküçük, Orhan Veli̇ Özkan
Investigation Of The Protective Effect Of Erdosteine Against Cyclosporine-Inducedinjury In Rat Liver With Histological And Biochemical Methods, Ahmet Nacar, İhsan Karaboğa, Hamza Mali̇k Okuyan, Nebi̇hat Kaplan Sefi̇l, Emel Nacar, Sedat Motor, Seçki̇n Akküçük, Orhan Veli̇ Özkan
Turkish Journal of Medical Sciences
Background/aim: In the present study, the protective effect of erdosteine against cyclosporine-induced injury in rat liver was investigated with histological and biochemical methods. Materials and methods: Thirty-two Wistar albino male rats were randomly divided into 4 groups: control (n = 8), cyclosporine (n = 8, 20 mg kg-1 day-1 i.p.), cyclosporine + erdosteine (n = 8, erdosteine 12 mg kg-1 day-1 orally), and erdosteine (n = 8). At the end of day 12, liver tissues were removed for histological and biochemical analysis. After liver tissues were fixed in 10% buffered neutral formalin, routine histological processes were applied and tissue sections …
Immunogenicity Of Conserved Cork And Ss-Barrel Domains Of Baumannii Acinetobactin Utilization Protein In An Animal Model, Yaqub Hajiaghatabar Sangroodi, Iraj Rasooli, Shahram Nazarian, Walead Ebrahimizadeh, Fatemeh Sefid
Immunogenicity Of Conserved Cork And Ss-Barrel Domains Of Baumannii Acinetobactin Utilization Protein In An Animal Model, Yaqub Hajiaghatabar Sangroodi, Iraj Rasooli, Shahram Nazarian, Walead Ebrahimizadeh, Fatemeh Sefid
Turkish Journal of Medical Sciences
Background/aim: The uptake of the ferric-acinetobactin complex into the periplasmic space relies on the baumannii acinetobactin utilization (BauA) protein. BauA is composed of cork and the β-barrel domains. We constructed a recombinant protein from conserved antigenic domains of cork and the β-barrel of BauA to evaluate their immunogenic role in an animal model. Materials and methods: The selected bauA domains were amplified from a purified genome of Acinetobacter baumannii ATCC 19606. The domains were then cloned into pET28a and the proteins expressed in E. coli BL21 (DE3) were purified using nickel nitrilotriacetic acid chromatography. Mice and rabbits were immunized with …