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Articles 211 - 240 of 334
Full-Text Articles in Medicine and Health Sciences
Cardiac Factors Affecting The Success Of Vardenafil In Erectile Dysfunction, Kürşad Zengi̇n, Hüseyi̇n Ede, Serhat Tanik, Sebahatti̇n Albayrak, Savaş Sarikaya, Ali̇riza Erbay, Muhammet Abdurrahi̇m İmamoğlu, Mesut Gürdal
Cardiac Factors Affecting The Success Of Vardenafil In Erectile Dysfunction, Kürşad Zengi̇n, Hüseyi̇n Ede, Serhat Tanik, Sebahatti̇n Albayrak, Savaş Sarikaya, Ali̇riza Erbay, Muhammet Abdurrahi̇m İmamoğlu, Mesut Gürdal
Turkish Journal of Medical Sciences
Background/aim: To evaluate the predictability of vardenafil success in patients with erectile dysfunction (ED) by using cardiological tests. Materials and methods: Patients diagnosed with ED who did not benefit from lifestyle changes (n = 68) were evaluated with an abridged 5-item version of the International Index of Erectile Function (IIEF-5). The pretreatment and posttreatment IIEF-5 scores were compared with pretreatment data obtained from cardiological examinations. Results: When pretreatment scores were compared with test parameters, mitral flow E/A ratio and tissue Doppler imaging (TDI) E?/A?, exercise test duration, exercise capacity in MET, and percentage of maximum heart rate were found to …
Sexuality And Sexual Dysfunction In Spinal Cord-Injured Men In Turkey, Ramazan Yavuz Akman, Evri̇m Coşkun Çeli̇k, Meti̇n Karataş
Sexuality And Sexual Dysfunction In Spinal Cord-Injured Men In Turkey, Ramazan Yavuz Akman, Evri̇m Coşkun Çeli̇k, Meti̇n Karataş
Turkish Journal of Medical Sciences
Background/aim: To provide a comprehensive evaluation of sexual function and dysfunction in spinal cord-injured men based on self-reports of patients. Materials and methods: Forty-seven spinal cord-injured men who completed the spinal shock and rehabilitation period were included. Patients were asked to complete a questionnaire developed to assess social status, sexual activities, abilities, and sexuality education after injury. Neurologic levels of patients were classified according to American Spinal Cord Injury Association protocol. Erectile function was evaluated by International Index of Erectile Function-5 (IIEF-5) questionnaire. Results: Patients were aged between 20 and 62 years (mean: 35.2). Twenty-eight patients had T10 and above, …
Esophageal Replacement By Hydroxylated Bacterial Cellulose Patch In A Rabbit Model, Changlai Zhu, Fang Liu, Wenbo Qian, Yingjie Wang, Qingsheng You, Tianyi Zhang, Feng Li
Esophageal Replacement By Hydroxylated Bacterial Cellulose Patch In A Rabbit Model, Changlai Zhu, Fang Liu, Wenbo Qian, Yingjie Wang, Qingsheng You, Tianyi Zhang, Feng Li
Turkish Journal of Medical Sciences
Background/aim: To repair esophageal defects by hydroxylated and kombucha -synthesized bacterial cellulose (HKBC) patch in a rabbit model. Materials and methods: Semicircular esophageal defects 1 cm in length of the cervical esophagus were initially created in 18 Japanese big-ear rabbits and then repaired with HKBC patch grafts. The clinical outcomes including survival rate, weight change, food intake, and hematological and radiologic evaluation were observed. After X-ray evaluation, the rabbits were sacrificed sequentially at 1, 3, and 6 months for histopathologic analysis with light microscopy and scanning electron microscopy. Results: Survival rate during the first month was 88.9% (n = 16). …
Multidrug Resistance And Integron Carriage In Clinical Isolates Ofpseudomonas Aeruginosa In Tehran, Iran, Somayeh Moazami Goudarzi, Fereshteh Eftekhar
Multidrug Resistance And Integron Carriage In Clinical Isolates Ofpseudomonas Aeruginosa In Tehran, Iran, Somayeh Moazami Goudarzi, Fereshteh Eftekhar
Turkish Journal of Medical Sciences
Background/aim: Pseudomonas aeruginosa is the cause of 10% of hospital-acquired infections. The organisms are often multidrug-resistant, mediated mostly by antibiotic-resistant integrons. The aim of this research was to study integron carriage and its association with multidrug resistance in burn and nonburn clinical isolates of P. aeruginosa. Materials and methods: A total of 112 P. aeruginosa clinical isolates were collected from the Motahari and Shohadaye Tajrish hospitals in Tehran between July and December 2011. Antibiotic susceptibility to 13 antibiotics was determined by disk diffusion. Detection of integron classes 1 and 2 and amplifications of internal variable regions (IVRs) of class 1 …
The Effects Of Aspirin, Flurbiprofen, And No-Donating Acetylsalicylic Acid(Ncx 4016) On Mice Models Of Endotoxic And Septic Shock, Nadi̇r Ulu, Alper Bektaş İski̇t, Cenk Sökmensüer, Mustafa Oğuz Güç
The Effects Of Aspirin, Flurbiprofen, And No-Donating Acetylsalicylic Acid(Ncx 4016) On Mice Models Of Endotoxic And Septic Shock, Nadi̇r Ulu, Alper Bektaş İski̇t, Cenk Sökmensüer, Mustafa Oğuz Güç
Turkish Journal of Medical Sciences
Background/aim: Nitric oxide-donating nonsteroidal antiinflammatory drugs (NO-NSAIDs) are a promising new class of antiinflammatory agents, which are obtained by adding NO-donating moieties to the existing conventional NSAID molecules. The aim of this study was to investigate the effects of aspirin, flurbiprofen, and NO-donating acetylsalicylic acid (NCX 4016) on cecal ligation and puncture (CLP) and endotoxin-induced septic shock (LPS) models in mice. Materials and methods: Overall survival and spleen and liver weights were monitored in LPS and CLP models. Histopathological examinations of liver and spleen were performed at the end of the experimental protocols. Results: NCX 4016 was able to reverse …
Epidemiology, Causative Agents, And Risk Factors Affecting Humanotomycosis Infections, Metwally Abdelazeem, Ahmed Gamea, Hanan Mubarak, Nessma Elzawawy
Epidemiology, Causative Agents, And Risk Factors Affecting Humanotomycosis Infections, Metwally Abdelazeem, Ahmed Gamea, Hanan Mubarak, Nessma Elzawawy
Turkish Journal of Medical Sciences
Background/aim: Otomycosis, or fungal otitis externa, has typically been described as fungal infection of the external auditory canal, with infrequent complications involving the middle ear. This study assessed a mycological analysis of fungal debris from external auditory canals of patients at Tanta University Hospital, Gharbia Governorate, Egypt. Materials and methods: The samples were collected over a year from the 110 patients that were clinically diagnosed to have otomycosis. The samples were then inoculated and culture plates were examined for the presence of fungal growth. Results: The results showed that Aspergillus niger was the most common fungus causing otomycosis. It was …
A Case-Control Study: Evaluation Of Vitamin D Metabolism In Patients With Vitiligo, Zennure Takci, Özlem Teki̇n, Derun Taner Ertuğrul, Ayşe Serap Karadağ, Kadi̇r Okhan Akin
A Case-Control Study: Evaluation Of Vitamin D Metabolism In Patients With Vitiligo, Zennure Takci, Özlem Teki̇n, Derun Taner Ertuğrul, Ayşe Serap Karadağ, Kadi̇r Okhan Akin
Turkish Journal of Medical Sciences
Background/aim: Reduced vitamin D is considered as one of the environmental factors that can increase the prevalence of certain autoimmune diseases. This study aimed to assess vitamin D metabolism in patients with vitiligo. Materials and methods: A prospective case-control study was conducted on 44 consecutive patients with vitiligo vulgaris and 43 healthy controls. Their plasma 25-hydroxyvitamin D (25(OH)D), parathormone (PTH), calcium, magnesium, and phosphate levels were measured. Results: There was no significant difference in the mean age, sex and Fitzpatrick skin phototype between the patient and control groups (P > 0.05). The plasma levels of 25(OH)D and calcium were signi?cantly decreased …
Effects Of Melatonin And Theanine Administration On Pentylenetetrazole-Inducedseizures And Brain Tissue Oxidative Damage In Ovariectomized Rats, Shadi Choopankareh, Farzaneh Vafaee, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Reza Salarinia, Leila Zarepoor, Mahmoud Hosseini
Effects Of Melatonin And Theanine Administration On Pentylenetetrazole-Inducedseizures And Brain Tissue Oxidative Damage In Ovariectomized Rats, Shadi Choopankareh, Farzaneh Vafaee, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Reza Salarinia, Leila Zarepoor, Mahmoud Hosseini
Turkish Journal of Medical Sciences
Background/aim: The effects of coadministration of melatonin and theanine (Mel/Thea) on pentylenetetrazole (PTZ)-induced seizures and brain tissue oxidative damage were investigated in ovariectomized (OVX) and sham-operated rats. Materials and methods: The rats were divided into the following groups: 1) sham, 2) ovariectomized (OVX), 3) sham-PTZ, 4) OVX-PTZ, 5) sham-Mel/Thea-PTZ, and 6) OVX-Mel/Thea-PTZ. Groups 1-4 received saline, while groups 5 and 6 received a combination of Mel/Thea for 6 weeks. All animals except for those in groups 1 and 2 received a single injection of PTZ. Results: The OVX-PTZ group had higher generalized tonic-clonic seizure (GTCS) latency compared to the sham-PTZ …
Hepatoprotective And Antioxidant Effects Of Lycopene In Acute Cholestasis, Mehmet Tokaç, Sevtap Aydin, Gökçe Taner, Alper Bi̇lal Özkardeş, Mi̇ne Yavuz Taşlipinar, Mehmet Doğan, Hali̇t Zi̇ya Dündar, Mehmet Kiliç, Ari̇f Ahmet Başaran, Ayşe Nurşen Başaran
Hepatoprotective And Antioxidant Effects Of Lycopene In Acute Cholestasis, Mehmet Tokaç, Sevtap Aydin, Gökçe Taner, Alper Bi̇lal Özkardeş, Mi̇ne Yavuz Taşlipinar, Mehmet Doğan, Hali̇t Zi̇ya Dündar, Mehmet Kiliç, Ari̇f Ahmet Başaran, Ayşe Nurşen Başaran
Turkish Journal of Medical Sciences
Background/aim: Lycopene, which is suggested to be a potent antioxidant, may play a protective role in diseases related to oxidative stress. In order to understand the effects of lycopene in the pathogenesis of cholestasis, we investigated the effects of lycopene on oxidative stress parameters and DNA damage induced by experimental biliary obstruction in the liver tissues and the lymphocytes of Wistar albino rats. Materials and methods: The animals were randomized into 3 groups. The sham group was subjected to a sham operation, the BDL group was subjected to bile duct ligation (BDL), and the BDL+L group was subjected to BDL …
Determination Of Apoptosis And Cell Cycle Modulators (P16, P21, P27, P53, Bcl-2,Bax, Bcl-Xl, And Cyclin D1) In Thyroid Follicular Carcinoma, Follicular Adenoma,And Adenomatous Nodules Via A Tissue Microarray Method, Peyker Temi̇z, Gi̇zem Akkaş, Nalan Neşe, Fazi̇let Uğur Duman, Cansu Karakaş, Yamaç Erhan
Determination Of Apoptosis And Cell Cycle Modulators (P16, P21, P27, P53, Bcl-2,Bax, Bcl-Xl, And Cyclin D1) In Thyroid Follicular Carcinoma, Follicular Adenoma,And Adenomatous Nodules Via A Tissue Microarray Method, Peyker Temi̇z, Gi̇zem Akkaş, Nalan Neşe, Fazi̇let Uğur Duman, Cansu Karakaş, Yamaç Erhan
Turkish Journal of Medical Sciences
Background/aim: To identify the role of gene products associated with apoptosis and cell cycle in the pathogenesis of thyroid follicular neoplasm. Materials and methods: Thirty follicular adenomas (FAs), 16 follicular carcinomas (FCs), and 20 adenomatous nodules (ANs) were investigated with immunohistochemical staining of p16, p21, p27, p53, Bcl-2, Bax, Bcl-xL, and cyclin D1 via a tissue microarray method. Results: Bcl-2 showed a significant difference between the benign groups (AN and FA) and the malignant group (FC). Bax was significantly higher in the FC group. p53 was lowest in the AN group and highest in the FC group with significant differences …
The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu
The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu
Turkish Journal of Medical Sciences
Background/aim: Mediastinoscopy is an invasive procedure that is used in the diagnosis of mediastinal diseases and in staging lung cancer. Tumor cell seeding during mediastinoscopy along the mediastinum and the incision line is a very rare complication. This study aimed to test the safety of mediastinoscopy in terms of tumor seeding by cytological evaluation of mediastinal lavage samples taken before and after biopsy. Materials and methods: The patients who underwent mediastinoscopy in our hospital between 2011 and 2014 were studied prospectively. Seventy-three patients with a diagnosis of lung or mediastinal malignancy were included in the study. All patients underwent classical …
Does Atraucan Cause More Postdural Puncture Backache?, Ruslan Abdullayev, Ömer Burak Küçükebe, Bülent Çeli̇k, Ni̇hal Ki̇rman, Hami̇t Si̇nan Hati̇poğlu, Fi̇li̇z Akaltun Hati̇poğlu
Does Atraucan Cause More Postdural Puncture Backache?, Ruslan Abdullayev, Ömer Burak Küçükebe, Bülent Çeli̇k, Ni̇hal Ki̇rman, Hami̇t Si̇nan Hati̇poğlu, Fi̇li̇z Akaltun Hati̇poğlu
Turkish Journal of Medical Sciences
Background/aim: Postdural puncture backache (PDPB) is the most frequent complaint after spinal anesthesia. In the literature its importance is generally overshadowed by postdural puncture headache. We studied two different kinds of spinal anesthesia needles to compare their technical handling capacities and incidences of PDPB. Materials and methods: Data of 256 pregnant female patients undergoing cesarean delivery under spinal anesthesia were collected for the study. Patients were divided into two groups as Group A (n = 109) and Group Q (n = 147) according to the spinal needle used for spinal anesthesia (i.e. 26-gauge atraumatic and 26-gauge Quincke needles, respectively). Backache …
Healthy Subjects' Knowledge Of Surgical Complications: A Hospital-Based Survey, Abdussamed Yalçin, Ersi̇n Gürkan Dumlu, Mehmet Tokaç, Ömer Parlak, Levent Öztürk, Mehmet Kiliç
Healthy Subjects' Knowledge Of Surgical Complications: A Hospital-Based Survey, Abdussamed Yalçin, Ersi̇n Gürkan Dumlu, Mehmet Tokaç, Ömer Parlak, Levent Öztürk, Mehmet Kiliç
Turkish Journal of Medical Sciences
Background/aim: There is an ongoing debate about how much a patient should know about serious or frequently occurring risks of their surgery. In this study, we evaluated healthy subjects' perspectives on knowledge of serious surgical complications. Materials and methods: Three hundred and thirty healthy subjects (151 women, 179 men; mean age: 43.6 ± 17.3 years) were surveyed with the study questionnaire. Social profile, surgical history of the healthy subjects, and presence of a relative while giving preoperative consent were assessed. Results: Only 23.5% (39/166) of the subjects were informed about all the potential complications of their previous surgical operation and …
Smoking Cessation And The Effect Of Nicotine Dependence Onrelapse Rate In İzmir, Turkey, Özlem Pekel, Gül Ergör, Türkan Günay, Hakan Baydur, Beri̇l Choussein, Refi̇k Budak, Si̇nem Doğanay
Smoking Cessation And The Effect Of Nicotine Dependence Onrelapse Rate In İzmir, Turkey, Özlem Pekel, Gül Ergör, Türkan Günay, Hakan Baydur, Beri̇l Choussein, Refi̇k Budak, Si̇nem Doğanay
Turkish Journal of Medical Sciences
Background/aim: Smoking is the leading preventable cause of death in the world. There is growing evidence of the need for community-based programs on smoking cessation. The main purpose of this study is to establish the rate of smoking cessation and restarting in 1 year at the Balçova Smoking Cessation Center. Materials and methods: This is a prospective study with a study group of 359 individuals who quit smoking at the Balçova Smoking Cessation Center for at least 4 weeks between October 2009 and April 2010. The outcomes of the study were 1-year cessation rate and relapse rate. Individuals who reported …
Epidemiological And Clinical Characteristics And Management Of Oropharyngeal Tularemia Outbreak, Mustafa Önder Uzun, Kerametti̇n Yanik, Müge Erdem, Uğur Kostakoğlu, Gürdal Yilmaz, Yeli̇z Tanriverdi̇ Çayci
Epidemiological And Clinical Characteristics And Management Of Oropharyngeal Tularemia Outbreak, Mustafa Önder Uzun, Kerametti̇n Yanik, Müge Erdem, Uğur Kostakoğlu, Gürdal Yilmaz, Yeli̇z Tanriverdi̇ Çayci
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to determine the epidemiological and clinical characteristics of patients diagnosed with tularemia and the effectiveness of the administered treatments. Materials and methods: Patients treated in our hospital between January 2009 and March 2011 and diagnosed with tularemia were evaluated retrospectively. Patients' epidemiological and clinical characteristics, administered treatments, and posttreatment findings were recorded on patient monitoring forms. Results: At anamnesis, 29% of patients used water from wells and 71% used water from the network supply; moreover, 48.4% had a history of contact with animals and 87.1% a history of lethargy. At physical examination, 96.8% …
Prevalence Of Hypertension And Its Association With Obesity Among Schoolchildren Aged 6-15 Living In Sakarya Province In Turkey, Fati̇h Muhammed Önsüz, Fi̇gen Demi̇r
Prevalence Of Hypertension And Its Association With Obesity Among Schoolchildren Aged 6-15 Living In Sakarya Province In Turkey, Fati̇h Muhammed Önsüz, Fi̇gen Demi̇r
Turkish Journal of Medical Sciences
Background/aim: Childhood hypertension and its association with obesity are becoming important issues worldwide. The prevalence of hypertension and obesity are growing in both developed and developing countries. This paper aimed to determine the prevalence of hypertension among school-aged children in Sakarya (western part of Turkey) and to determine whether or not obesity is associated with hypertension. Materials and methods: Twelve schools were randomly selected from an area in the center of the Sakarya. A total of 2166 students participated in the study. The students were visited at school, and their weights, heights, and blood pressures were measured. The World Health …
Vkorc1 And Cyp2c9 Genotypic Data-Based Dose Prediction Alone Does Not Accurately Predict Warfarin Dose Requirements In Some Malaysian Patients, Yung An Chua, Wan Zaidah Abdullah, Zurkurnai Yusof, Siew Hua Gan
Vkorc1 And Cyp2c9 Genotypic Data-Based Dose Prediction Alone Does Not Accurately Predict Warfarin Dose Requirements In Some Malaysian Patients, Yung An Chua, Wan Zaidah Abdullah, Zurkurnai Yusof, Siew Hua Gan
Turkish Journal of Medical Sciences
Background/aim: VKORC1 and CYP2C9 genetic polymorphisms may not accurately predict warfarin dose requirements. We evaluated an existing warfarin dosing algorithm developed for Malaysian patients that was based only on VKORC1 and CYP2C9 genes. Materials and methods: Five Malay patients receiving warfarin maintenance therapy were investigated for their CYP2C9*2, CYP2C9*3, and VKORC1-1639G>A genotypes and their vitamin K-dependent (VKD) clotting factor activities. The records of their daily warfarin doses and international normalized ratio (INR) 2 years prior to and after the measurement of VKD clotting factors activities were acquired. The mean warfarin doses were compared with predicted warfarin doses calculated from …
Antibiofilm Activity Of Trans-Cinnamaldehyde, P-Coumaric, And Ferulic Acids On Uropathogenic Escherichia Coli, Barbara Kot, Jolanta Wicha, Malgorzata Piechota, Katarzyna Wolska, Agata Gruzewska
Antibiofilm Activity Of Trans-Cinnamaldehyde, P-Coumaric, And Ferulic Acids On Uropathogenic Escherichia Coli, Barbara Kot, Jolanta Wicha, Malgorzata Piechota, Katarzyna Wolska, Agata Gruzewska
Turkish Journal of Medical Sciences
Background/aim: Biofilm on urinary catheters results in persistent infections that are resistant to antibiotics. In this study, phytochemicals were assessed as alternative antimicrobials in preventing and inactivating E. coli biofilm on urinary catheters. Materials and methods: Biofilm prevention was tested using catheter fragments inoculated with E. coli and treated with trans-cinnamaldehyde, p-coumaric, and ferulic acids (0%, 0.1%, 0.25%, and 0.5%) for 0, 1, 3, and 5 days. Inactivation of E. coli biofilm with the same agents at concentrations of 0%, 1%, 1.25%, or 1.5% used for 0, 1, 3, or 5 days was also evaluated. Results: All used concentrations of …
Prevalence Of Helicobacter Pylori Caga, Baba2, And Dupa Genotypes Andcorrelation With Clinical Outcome In Malaysian Patients With Dyspepsia, Hussein Ali Osman, Habsah Hasan, Rapeah Suppian, Syed Hassan, Dzulkarnaen Zakaria Andee, Noorizan Abdul Majid, Bin Alwi Zilfalil
Prevalence Of Helicobacter Pylori Caga, Baba2, And Dupa Genotypes Andcorrelation With Clinical Outcome In Malaysian Patients With Dyspepsia, Hussein Ali Osman, Habsah Hasan, Rapeah Suppian, Syed Hassan, Dzulkarnaen Zakaria Andee, Noorizan Abdul Majid, Bin Alwi Zilfalil
Turkish Journal of Medical Sciences
Background/aim: The severity of disease outcome in dyspepsia has been attributed to Helicobacter pylori virulence genes. The aim of this study was to determine the distribution of H. pylori virulence genes (cagA, babA2, and dupA) and to determine whether or not there arises a significant correlation with clinical dyspepsia outcomes. Materials and methods: H. pylori genotypes cagA, babA2, and dupA were identified by polymerase chain reactions from gastric biopsy samples in 105 H. pylori-positive patients. Results: The positive rates for cagA, babA2, and dupA genes in H. pylori dyspeptic patients were 69.5%, 41.0%, and 22.9%, respectively. cagA was more prevalent …
Effects Of Pretreatment With Esmolol And Lidocaine On Injection Pain Androcuronium-Induced Withdrawal Response, Jüli̇de Ergi̇l, Fatma Kavak Akelma, Derya Özkan, Gözde Bumi̇n Aydin, Ayşe Gürel, Meli̇h Akinci
Effects Of Pretreatment With Esmolol And Lidocaine On Injection Pain Androcuronium-Induced Withdrawal Response, Jüli̇de Ergi̇l, Fatma Kavak Akelma, Derya Özkan, Gözde Bumi̇n Aydin, Ayşe Gürel, Meli̇h Akinci
Turkish Journal of Medical Sciences
Background/aim: We aimed to compare the effectiveness of esmolol 1 mg/kg and lidocaine 1 mg/kg for injection pain and for the prevention of rocuronium-induced withdrawal response. Materials and methods: We enrolled a total of 81 patients in the study. Patients were randomly assigned to receive either 10 mL of 0.9% NaCl (Group P), esmolol 1 mg/kg (Group E), or lidocaine 1.0 mg/kg (Group L). A subparalyzing dose of rocuronium 0.05 mg/kg was administered to all patients and its effects were recorded. Anesthesia was induced with intravenous propofol and intravenous rocuronium 0.5 mg/kg in all groups. The withdrawal movements of the …
Evaluation Of Patency Following Revision Technique Ofhigh-Velocity Arteriovenous Fistula, Ümi̇t Halici, Mehmet Ali̇ Kaygin, Özgür Dağ, Ahmet Aydin, Hüsnü Kami̇l Li̇mandal, Ümi̇t Arslan, Eyüp Serhat Çalik, Bi̇lgehan Erkut
Evaluation Of Patency Following Revision Technique Ofhigh-Velocity Arteriovenous Fistula, Ümi̇t Halici, Mehmet Ali̇ Kaygin, Özgür Dağ, Ahmet Aydin, Hüsnü Kami̇l Li̇mandal, Ümi̇t Arslan, Eyüp Serhat Çalik, Bi̇lgehan Erkut
Turkish Journal of Medical Sciences
Background/aim: The objective of this study is to report our experience with surgical revision of dialysis access-induced ischemia syndrome. Materials and methods: Between January 2005 and July 2013, 1254 patients underwent arteriovenous fistula operation, and 86 of them [53 males, mean age: 55 ± 25 (range: 25 to 75) years; 33 females, mean age: 50 ± 20 (range: 30 to 70) years] subsequently developed steal syndrome. These patients were treated with arterial pressure-controlled polytetrafluoroethylene banding or constriction with polypropylene suturing technique. Patients were followed in the outpatient clinic at regular intervals. Results: Symptoms were not relieved during the first 15 …
Investigation Of The Effect Of Changes In Muscle Strength In Gestational Ageupon Fear Of Falling And Quality Of Life, Emrah Atay, Fatma Başalan İz
Investigation Of The Effect Of Changes In Muscle Strength In Gestational Ageupon Fear Of Falling And Quality Of Life, Emrah Atay, Fatma Başalan İz
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is the investigation of the effect of changes in muscle strength in gestational age upon fear of falling and quality of life. Materials and methods: This longitudinal, descriptive study included a sample of 37 pregnant women who volunteered to participate. The research data were collected at 20 and 32 weeks of gestation. Data collection instruments included a newly developed questionnaire form, the Tinetti Falls Efficacy Scale, a visual analog scale, and the Turkish language version of the WHO Quality of Life Scale. Upper body flexibility was measured by the back scratch test, while muscle …
Risk Factors And Maximum Standardized Uptake Values Within Lymph Nodes Of Anthracosis Diagnosed By Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration, Ni̇lgün Yilmaz Demi̇rci̇, İbrahi̇m Onur Alici, Aydin Yilmaz, Funda Demi̇rağ, Ebru Tatci, Yurdanur Erdoğan
Risk Factors And Maximum Standardized Uptake Values Within Lymph Nodes Of Anthracosis Diagnosed By Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration, Ni̇lgün Yilmaz Demi̇rci̇, İbrahi̇m Onur Alici, Aydin Yilmaz, Funda Demi̇rağ, Ebru Tatci, Yurdanur Erdoğan
Turkish Journal of Medical Sciences
Background/aim: Enlarged mediastinal lymph nodes can result from serious etiologies including granulomatous disease, neoplasia, etc., and a rare condition called anthracosis . The aim of this study was to determine the incidence of risk factors and the uptake values within the anthracotic lymph nodes. Materials and methods: 106 patients who underwent endobronchial ultrasound transbronchial needle aspiration and were diagnosed as having anthracosis were analyzed retrospectively. Patients with positive confirmation by surgical biopsies or a 1-year follow-up period were enrolled. Results: 201 lymph nodes were sampled from 106 patients. Subcarinal and interlobar lymph nodes were the most commonly affected stations (36.8% …
Value Of Prealbumin In Assessment Of Nutrition For Critically Ill Patients, Mehmet Ağilli, Şafak Eki̇nci̇
Value Of Prealbumin In Assessment Of Nutrition For Critically Ill Patients, Mehmet Ağilli, Şafak Eki̇nci̇
Turkish Journal of Medical Sciences
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Role Of Autophagy In The Pathogenesis Of Alzheimer Disease, Muhammet Cemal Kizilarslanoğlu, Zekeri̇ya Ülger
Role Of Autophagy In The Pathogenesis Of Alzheimer Disease, Muhammet Cemal Kizilarslanoğlu, Zekeri̇ya Ülger
Turkish Journal of Medical Sciences
Alzheimer disease (AD) is the most common progressive neurodegenerative disorder causing increased morbidity and mortality. It is characterized by accumulation of amyloid-β in neurons. As there is no known definitive treatment of this disorder, studies trying to determine its exact pathogenetic pathways and target therapies for these specific pathways are being rapidly conducted. Autophagy is one of the areas of interest in studies on the pathogenesis of AD. It is a process of self-digestion that is thought to be a response to stressors and allows cells to adapt to environmental changes. There is accumulating evidence showing an association between autophagy …
Why Is Alzheimer's Disease Confused With Other Dementias?, Dursun Aygün, İbrahi̇m Levent Güngör
Why Is Alzheimer's Disease Confused With Other Dementias?, Dursun Aygün, İbrahi̇m Levent Güngör
Turkish Journal of Medical Sciences
Alzheimer disease (AD) is the most common cause of dementia. The cardinal manifestation of AD is progressive loss of memory. However, there are some nonamnestic presentations of AD, also called atypical AD. Symptoms of AD can sometimes start suddenly. In the presence of atypical symptoms or sudden onset, it may be difficult to distinguish AD from other dementias. We would like to discuss the confusing features of atypical AD that mimic other dementias. In this review, the literature associated with confusing features of AD, suggesting other dementia syndromes, is reviewed. In addition, a case of semantic dementia (SD) with the …
Postoperative Cognitive Dysfunction And Alzheimer Disease, Berri̇n Işik
Postoperative Cognitive Dysfunction And Alzheimer Disease, Berri̇n Işik
Turkish Journal of Medical Sciences
Alzheimer disease (AD) is the most prevalent neurodegenerative disorder in elderly people. Patients with AD appear to be particularly at risk for cognitive deterioration following anesthesia. Some in vitro studies suggest that exposure to general anesthesia (GA) promotes the AD process. On the other hand, there are no clinical studies that clearly demonstrate that GA is a cause of cognitive dysfunction in patients with probable AD. The aim of this research was to discuss the relation between postoperative cognitive dysfunction (POCD) and AD according to the literature. In vivo studies examining AD biomarkers postoperatively and in vitro studies exploring amyloid-β …
Nutritional Issues In Dementia Patients, Mustafa Kemal Kiliç, Fati̇h Sümer, Zekeri̇ya Ülger
Nutritional Issues In Dementia Patients, Mustafa Kemal Kiliç, Fati̇h Sümer, Zekeri̇ya Ülger
Turkish Journal of Medical Sciences
Dementia is an inevitable disease of aging, leading not only to diminished cognitive ability but also behavioral changes, malnutrition, pressure sores, and infections. Acknowledging common problems and their solutions is essential for any health service worker who deals with demented geriatric patients.
Alzheimer Disease And Anesthesia, Gözde İnan, Zerri̇n Özköse Şatirlar
Alzheimer Disease And Anesthesia, Gözde İnan, Zerri̇n Özköse Şatirlar
Turkish Journal of Medical Sciences
Alzheimer disease (AD) is one of the most common neurodegenerative diseases and the most prevalent form of dementia. Some factors in the development of AD, age being the best-known one, have been suggested; however, no causes have been found yet. The pathophysiology of the disease is highly complex, current therapies are palliative, and a cure is still lacking. Adverse effects of anesthetics in the elderly have been reported since the 1950s; however, awareness of this old problem has recently gained importance again. Whether exposure to surgery and general anesthesia (GA) is associated with the development of AD has been questioned. …
A Comparison Of Hair And Serum Trace Elements In Patients With Alzheimer Disease And Healthy Participants, Emi̇ne Rabi̇a Koç, Ati̇lla İlhan, Zübeyde Aytürk, Burcu Acar, Mukaddes Gürler, Aynur Altuntaş, Mustafa Karapi̇rli̇, Abdurrahman Sai̇d Bodur
A Comparison Of Hair And Serum Trace Elements In Patients With Alzheimer Disease And Healthy Participants, Emi̇ne Rabi̇a Koç, Ati̇lla İlhan, Zübeyde Aytürk, Burcu Acar, Mukaddes Gürler, Aynur Altuntaş, Mustafa Karapi̇rli̇, Abdurrahman Sai̇d Bodur
Turkish Journal of Medical Sciences
Background/aim: To determine whether there was a difference between serum and hair trace elements' concentrations in patients with Alzheimer disease (AD) and healthy participants. Materials and methods: Hair and serum copper, selenium, zinc, magnesium, manganese, and iron levels were measured by inductively coupled plasma-mass spectrometry in patients with AD and healthy participants, and the obtained results were statistically compared. Results: The mean hair selenium and zinc levels of patients with AD were significantly lower than the levels found for control participants (P < 0.05). Patients with AD had significantly higher mean hair copper and manganese levels than the controls. There were no significant differences between AD patients and controls with respect to the hair iron and magnesium levels (P > 0.05). Hair and serum trace element (copper, selenium, zinc, magnesium, manganese, and iron) levels in patients with AD …