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Articles 1831 - 1831 of 1831
Full-Text Articles in Cancer Biology
The Effects Of Intraperitoneal Injections Of Methylene Blue On Sarcoma 37 In Mice, Jennifer Sullivan
The Effects Of Intraperitoneal Injections Of Methylene Blue On Sarcoma 37 In Mice, Jennifer Sullivan
Student Scholarship
This research investigates the quantitative effects of methylene blue on the growth of transplanted sarcoma 37 in Swiss mice. While some previous literature suggested that oral administration of this thiazine dye could inhibit certain carcinomas, this study focuses on the results of direct intraperitoneal injections. The experimental process involved injecting mice with varying concentrations of the dye and allowing a nine-day growth period before removing the tumors for microscopic analysis. The primary metric for determining growth effects was the mitotic count, which involved averaging the number of dividing cells across multiple sections and fields for each tumor.
The results indicate …