Life Sciences Commons^™

Zellweger Spectrum Disorder: A Cross-Sectional Study Of Symptom Prevalence Using Input From Family Caregivers, Mousumi Bose, David D. Cuthbertson, Marsha A. Fraser, Jean Baptiste Roullet, K. Michael Gibson, Dana R. Schules, Kelly M. Gawron, Melissa B. Gamble, Kathryn M. Sacra, Melisa J. Lopez, William B. Rizzo

Department of Nutrition and Food Studies Scholarship and Creative Works

Zellweger spectrum disorders (ZSD) are rare, debilitating genetic diseases of peroxisome biogenesis that affect multiple organ systems and present with broad clinical heterogeneity. Although many case studies have characterized the multitude of signs and symptoms associated with ZSD, there are few reports on the prevalence of symptoms to help inform the development of meaningful endpoints for future clinical trials in ZSD. In the present study, we used an online survey tool completed by family caregivers to study the occurrence, frequency and severity of symptoms in individuals diagnosed with ZSD. Responses from caregivers representing 54 living and 25 deceased individuals with …

Unconventional Constituents And Shared Molecular Architecture Of The Melanized Cell Wall Of C. Neoformans And Spore Wall Of S. Cerevisiae, Christine Chrissian, Coney Pei-Chin Lin, Emma Camacho, Arturo Casadevall, Aaron M. Neiman, Ruth E. Stark

Publications and Research

The fungal cell wall serves as the interface between the cell and the environment. Fungal cell walls are composed largely of polysaccharides, primarily glucans and chitin, though in many fungi stress-resistant cell types elaborate additional cell wall structures. Here, we use solid-state nuclear magnetic resonance spectroscopy to compare the architecture of cell wall fractions isolated from Saccharomyces cerevisiae spores and Cryptococcus neoformans melanized cells. The specialized cell walls of these two divergent fungi are highly similar in composition. Both use chitosan, the deacetylated derivative of chitin, as a scaffold on which a polyaromatic polymer, dityrosine and melanin, respectively, is assembled. …

Nebline, November/December 2020

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Nebraska Extension Celebrates 20 Years of School Enrichment Nutrition Kits!

Recipe of the Month

Fun Winter Gardening Projects

Garden Guide: Things to Do This Month

Be a Master Gardener!

Upcoming Green Industry Conferences

Helping Foster a Growth Mindset in Young Children

Pesticide Applicator Trainings

Landlord/Tenant Lease & Crop Budget Workshops

Extension News

4-H Announcements for enrolled 4-H'ers or 4-H volunteers

Heart of 4-H Volunteer Award: Jodi Gabel

Heart of 4-H Volunteer Award: Sarah Lanik-Frain and Mike Frain

2020 4-H Horse Awards

Extension Calendar

Outgoing 4-H Council Members

Youth Science Day for Homeschooled Youth

Ag Society Annual Election & Meeting

Super …

Availability And Consumption Of Vitamin A Foods Among Southern Ethiopian And Zambian Primary Students, Trang Vuong

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Understand vitamin A food availability in open-air markets (OAM’s), and consumption of those foods by primary school children in southern Ethiopia/Zambia.

Methods: Conducted inventories of all consumable/potable items and interviewed 6-7th grade students about consumption of items with vitamin A.

Results: Students consumed most of the 14 vitamin A foods/items sold in OAM’s. Zambian students ate more liver, pumpkin, squash, watermelon, and wild fruits, while Ethiopian students almost never consumed squash, watermelon or wild fruits.

Conclusions: The availability of Vitamin A foods in Ethiopian and Zambian OAMs are varied; however, Zambian children reportedly eat more vitamin A foods. Nutrition …

The Virome Of Peony And The Population Structure Of Its Most Prominent Viruses, Cullen Shaffer

Graduate Theses and Dissertations

Peony (Peonia lactiflora, Pall.) is a popular ornamental that has been cultivated for millennia. Due to its popularity, plant material is frequently moved across international borders allowing for the spread of viruses. The virome of several peony plants was investigated and four viruses; namely Amazon lily mild mottle virus (ALiMMV), Cycas necrotic stunt virus (CNSV), Gentian Kobu-sho associated virus (GKaV) and Lychnis mottle virus (LycMoV) were detected for the first time in the Western Hemisphere. Incidence ranged from a few plants for ALiMMV to near universal infection for CNSV. GKaV was found in individuals that were infected with Lemoine’s disease …

Parallel Strategies To Control Bacterial Panicle Blight Of Rice, Laura Ortega

Graduate Theses and Dissertations

Bacterial Panicle Blight (BPB) of rice is a seed-borne disease caused by the bacterium Burkholderia glumae. This disease has affected rice production worldwide and its effects are likely to become more devastating with the continuous increase in global temperatures especially during the growing season. Field data has shown that the disease has been more prevalent in years when the temperatures have been unusually high especially at night possibly due to the bacterial adaptation to grow at temperatures higher than 40oC. With the continuous rise in global temperatures, it is likely that this disease will be more problematic. The bacterium can …

The Role Of Prenatal Food Insecurity On Breastfeeding Behaviors: Findings From The United States Pregnancy Risk Assessment Monitoring System, Lauren Dinour, Elizabeth I. Rivera Rodas, Ndidiamaka Amutah-Onukagha, Laurén A. Doamekpor

Department of Nutrition and Food Studies Scholarship and Creative Works

Background

In addition to its health and nutritional benefits, breastfeeding can save low-income, food insecure mothers the cost of infant formula so that money can be spent on food and other necessities. Yet breastfeeding may exacerbate food insecurity by negatively affecting maternal employment. The relationship between food insecurity and breastfeeding has been explored previously, with varying results. The purpose of this study was to determine the relationship between prenatal food insecurity and breastfeeding initiation and early cessation (< 10 weeks) among U.S. mothers.

Methods

Data were pooled from 2012 to 2013 (Phase 7) of the Pregnancy Risk Assessment Monitoring System, a population-based cross-sectional survey of …

Lung Cancer, Ahana Narayanan, Maia Peregrino, Moorea Gay

Human Diseases Graphic Novels

No abstract provided.

Celiac Disease, Maia Peregrino, Ahana Narayanan, Moorea Gay

Human Diseases Graphic Novels

No abstract provided.

Nervous System: Alzheimer’S Disease, Krisha Patel, Saachi Kumar, Delicia Chen

Human Diseases Graphic Novels

No abstract provided.

The Use Of Bacteriophages For Food Safety, Lorraine Endersen, Aidan Coffey

Department of Biological Sciences Publications

The search for natural biocontrol agents that allow the production of foods that are safe for human consumption and do not impact the taste, texture, and nutritional quality of the food, is a constant challenge for diverse food industries worldwide, particularly as the human population continues to rise globally, and multiple antibiotic resistance in pathogenic bacteria is increasingly prevalent. Bacteriophages (phages), the naturally occurring predators of bacteria, are harmless to humans and animals and are ubiquitous in the environment — and as such, have been recognised as promising antimicrobial agents to help control specific bacterial pathogens in food production. This …

Biodiversity And Ecology Of Lichens Of Kenai Fjords National Park, Alaska, Roger Rosentreter

Biology Faculty Publications and Presentations

We inventoried lichens in Kenai Fjords National Park in Alaska, USA We assembled the known information on occurrence and ecology of lichens in this park by combining field, herbarium, and literature studies. Our results provide baseline data on lichen occurrence that may be used in resource condition assessments, vulnerability assessments, long-term ecological monitoring, and resource management. We report a total of 616 taxa of lichenized fungi from the Park, plus an additional five subspecies and three varieties, all of which are new additions to the National Park Service database for this park unit. An additional five species of nonlichenized lichenicolous …

Spatial Profiling Of Gangliosides In Mouse Brain By Mass Spectrometry Imaging, Douglas A. Andres, Lyndsay E. A. Young, Matthew S. Gentry, Ramon C. Sun

Molecular and Cellular Biochemistry Faculty Publications

No abstract provided.

Resistance To Herbicides Conferred By Amaranthus Palmeri Protoporphyrinogen Ix Oxidase Mutations, Pamela Carvalho De Lima

Graduate Theses and Dissertations

Palmer amaranth (Amaranthus palmeri S. Wats.) is one of the most problematic agronomic weeds to control in fields across Arkansas. Thus far, this species has evolved resistance to several herbicides, including protoporphyrinogen IX oxidase (PPO) inhibitors. The majority of PPO-resistant Palmer amaranth populations harbor a target-site mutation (substitution or deletion of amino acids). The objective of this thesis was to identify the level of fomesafen resistance conferred by PPO2 mutations from Palmer amaranth. The experiments conducted aimed to (1) characterize the level of resistance conferred by the transgene Palmer amaranth ppo2 carrying ΔG210 mutation into the wild type rice (Oryza …

Supersize It! Developing A "Supercytoplast" Through Platelet Fusion, Taulbee B. Gunter

Animal Science Undergraduate Honors Theses

Stem cell research opens a wide range of possibilities from lab-grown tissues for medical purposes to cloned animals for livestock production. The issue with one of the most popular forms of cell recombination into a stem cell, known as somatic cell nuclear transfer (SCNT), is that it requires an oocyte. The requirement of an oocyte is often the host of public scrutiny for its economic and ethical issues. Platelets may offer a less expensive and more accessible alternative to oocytes as sources of naturally enucleated cells. Thus, the objective of this explorative research project is to isolate and fuse platelets …

Ensemble Learning With Recursive Partitioning Methods To Explore Relationships Between Mental Health And Physical Activity, Jessica Gilmore

Health, Human Performance and Recreation Undergraduate Honors Theses

Physical and mental health are imperative to maintaining a well functioning immune system, which is especially critical during a global pandemic. Moreover, physical and mental health contribute to the overall quality of life experienced by an individual. Consequently, it is important to explore factors that contribute to both physical and mental health. Physical activity has been previously shown to improve physical and mental health yet many individuals do not get enough physical activity daily. Using data collected during the larger Exercise is Medicine (EIM) study, the current study utilized ensemble learning with recursive partitioning methods to explore the relationships that …

Choice Of End State Comfort Based On Time Spent At The Beginning State And The Precision Requirement Of The End State, Tucker Gregory Gamble

Undergraduate Honors Capstone Projects

People choose actions based on many different variables. In particular, choice of posture while grasping an object typically depends upon several factors including the time spent in that posture, what postures were held prior to choosing that posture, and the precision required by the posture. The purpose of this study was to test a trade-off between choice of end-state comfort based on time spent in a posture at the beginning-state and the precision requirement of the end-state. A comfortable grasp is classified when a person has a full grasp on an object with their thumb pointing up. This posture also …

Effect Of Biocrust Development On Establishment Of Native Plants In A Salt Desert System, Merran Owen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Salt desert shrublands are semiarid, shrub-dominated ecosystems that inhabit salt- affected soils. In Great Basin salt deserts, exotic annual plants are invading and displacing native plants. Low plant productivity and slow population growth of native plants in these ecosystems makes them vulnerable to invasion and limits their ability to compete with invasive plants and return to a natural state. Active revegetation efforts, such as planting and direct seeding of native plants, are often unsuccessful for the same reasons. Biological soil crusts (communities of cyanobacteria, lichen, moss, microfungi and other microorganisms that live on the surface layer of the soil) are …

Demographics, Accuracy, And Impact Of Feed Laboratories In The United States, Jerald H. Severe

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Feed analysis is very important to modern society. In the United States feed analysis is used to optimize production of food animals. Feed analysis is also used as a tool to place value on crops. As important as feed analysis is to society, little research has been done that describes which feed laboratories are the most popular and why people use them. It has been thought by some patrons that different results from the same feed sample are obtained by different laboratories. Is this true? If so, what is the effect on those that use feed laboratories to produce animals, …

The Consequences Of Environmental Properties And Tree Spatial Neighborhood On Post-Fire Structure Of Forest In Yosemite National Park, Jelveh Tamjidi

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Separating the contribution of habitat filtering and dispersal mechanisms in forming species distribution remains a challenge in community ecology. Despite the effect of environmental variables in structuring communities, only restricted numbers of them were considered as a habitat dissimilarity.

In Chapter 2, I used topography and soil properties to define habitats within the Yosemite Forest Dynamics Plot (YFDP). The soil enzymes were added in soil samples due to their important role in releasing nutrients into the soil environment. The preference of eleven species to a specific habitat were examined. Also, the relative importance of habitat filtering and dispersal limitation were …

Classification And Prediction Models For Natural Streamflow Regimes In The Arid Southwestern Usa, Angela M. Merritt

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Understanding how natural variation in flow regimes influences stream ecosystem structure and function is critical to the development of effective stream management policies and actions. Spatial variation in flow regimes is well understood for stream reaches in mesic regions, but a more robust characterization of flow regimes in arid regions is needed, especially to support biological monitoring and assessment programs. Methods are specifically needed that can accurately predict the flow regime expected at ungauged reaches. We used long-term (41 y) records of mean daily flow from 287 stream reaches in the arid western USA to develop and compare several alternative …

Fruit Tree Responses To Water Stress: Automated Physiological Measurements And Rootstock Responses, William D. Wheeler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

New orchard plantings utilize trees grafted to dwarfing rootstocks planted close together to facilitate larger harvests. These dwarfing rootstocks have not been comprehensively studied for their ability to withstand drought. This is of special importance in the Intermountain West which has limited rainfall. Additionally, orchard growers face competition for water from a growing population and increased uncertainty in rainfall from climate change. My research examined the use of dendrometers, which measure changes in trunk diameter, and sap flow sensors, which measure how quickly sap moves, as methods to inform growers about tree water status. I also used a weighing lysimeter …

Undergraduate Students Use Moral Reasoning And Belief In Genetic Determinism In Response To A Crispr/Cas9 Socioscientific Issue., Katie M. Seiter

Electronic Theses and Dissertations

This dissertation explores how students reason about genetic engineering socioscientific issues (SSIs) related to a recently developed, powerful genome editing technology called CRISPR/Cas9. It is divided into three chapters. Chapter One describes an exploratory study that characterized students’ moral reasoning using a sociocultural theoretical framework. I used content analysis and logistic regression to investigate how academic and social factors influenced moral reasoning. Students generally opposed the use of CRISPR/Cas9 technology for non-medical enhancements, and the moral considerations used were influenced by genetics knowledge level and demographic variables such as gender and socio-economic status. Further investigation of moral perspectives for students …

Implementation Of A Guideline For Major Depressive Disorder In A Private Practice Clinic, Doreen Phillips

Doctor of Nursing Practice

Major depressive disorder (MDD) is a chief mental health illness that carries a profound economic burden. Many who suffer from MDD find little to no relief with traditional pharmacological interventions.The 2010 American Psychiatric Association Guidelines for Treatment of Patients with MDD recognized TMS as a second-line treatment choice. Several double-blind, randomized controlled trials illustrated the efficacy and safety of TMS as a viable treatment option for MDD. The purpose of this project was to implement standardized processes through the use of a treatment guideline to help provide comprehensive treatment options for patients suffering from moderate to severe major depressive disorder …

Forage News [2020-12], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

No abstract provided.

New Hints Towards A Precision Medicine Strategy For Idh Wild-Type Glioblastoma., K White, K Connor, J Clerkin, B M Murphy, M Salvucci, A C O'Farrell, M Rehm, D O'Brien, J H M Prehn, S P Niclou, M L M Lamfers, M Verreault, A Idbaih, Roel G W Verhaak, A Golebiewska, A T Byrne

Faculty Research 2020

Glioblastoma represents the most common primary malignancy of the central nervous system in adults and remains a largely incurable disease. The elucidation of disease subtypes based on mutational profiling, gene expression and DNA methylation has so far failed to translate into improved clinical outcomes. However, new knowledge emerging from the subtyping effort in the IDH-wild-type setting may provide directions for future precision therapies. Here, we review recent learnings in the field, and further consider how tumour microenvironment differences across subtypes may reveal novel contexts of vulnerability. We discuss recent treatment approaches and ongoing trials in the IDH-wild-type glioblastoma setting, and …

Biofilms Of The Non-Tuberculous Mycobacterium Chelonae Form An Extracellular Matrix And Display Distinct Expression Patterns, Perla Vega-Dominguez, Eliza Jr Peterson, Min Pan, Alessandro Di Maio, Saumya Singh, Siva Umapathy, Deepak K Saini, Nitin Baliga, Apoorva Bhatt

Articles, Abstracts, and Reports

No abstract provided.

Holt & Plyler (1984) Checklist Of The Vascular Flora Of The Robert B. Gordon Natural Area, Jack Holt, Jim Plyler

Gordon Natural Area Baseline Plant Survey Documents

This research represents the first site-wide floristic survey of the Gordon Natural Area (GNA), and consists of 348 species in 238 genera and 95 families. The survey was conducted by two West Chester University undergraduate students, Jack Holt and Jim Plyler, under the supervision of Dr. William Overlease. The bulk of the work took place during 1984; however, some woody species previously noted in the GNA by Jim Plyler were also incorporated into the list. The checklist was compiled for all vascular families encountered at the GNA, with the exception of the Grass Family (Poaceae), Rush Family (Juncaceae), and Sedge …

Fall Field Report, August-November 2020, W. Ross Silcock

Nebraska Bird Review

Two issues were of concern this fall, and both appeared to have consequences or at least similarities in Nebraska. A major die-off in New Mexico made national news: https://www.aba.org/the-data-behind-mysterious-bird-deaths-in-new-mexico/. On Sep 9, 2020, the temperature dropped from 96°F to 40°F in the Albuquerque area, a record low, winds reached 70 mph, and several inches of snow fell, killing large numbers of birds directly. Over the next few days, hundreds more dead birds were picked up. Some have linked this high mortality to birds displaced from the mountains due to fire and unfortunately being caught in the severe weather. While fire …

History Of The Seward-Branched Oak Lake Christmas Bird Count, 1993-2020, Joseph A. Gubanyi

Nebraska Bird Review

The Seward-Branched Oak Lake Christmas Bird Count (Seward-BOL CBC) began in 1993 and has been conducted every year since then except for 2010 for a total of 27 counts. Weather conditions prevented the count on the selected date in 2010 and a backup date could not be set up. The count was started for several reasons. The area west of Lincoln has a diversity of habitats including all or part of four public lakes (Branched Oak, Pawnee, Twin Lakes, and Meadowlark) as well as a diversity of terrestrial habitats on both public and private land. The circle is close to …