Life Sciences Commons^™

Smokejumper Obituary: Holmes, Michael Alden "Mike" (Missoula 1966), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

The Neuroinflammatory Effects Of Chronic Unpredictable Stress On Zebrafish, Danio Rerio, Brandon Stewart

Master of Science in Integrative Biology Theses

Stress is a state of threatened homeostasis counteracted by various physiologic and behavioral responses aimed to maintain or restore balance. As such, stress acts as a motivator to perform during the challenges of life to survive. Chronic perturbations to the stress response homeostasis without relief can lead to dysregulation, thus attenuating organ systems and structures and causing significant damage ^{1]. Individuals who undergo psychological trauma endure an acute and transient experience, which results in minimal functional impairment, but some suffer from a chronic condition called posttraumatic stress disorder (PTSD). Individuals who have PTSD are likely to experience intense stress, …

Pd-L1 Expression On Circulating Tumor Cells May Be Predictive Of Response To Pembrolizumab In Advanced Melanoma: Results From A Pilot Study, Muhammad K. Khattak, Anna L. Reid, James Freeman, Michelle Pereira, Ashleigh Mcevoy, Johnny Lo, Markus Frank, Tarek Meniawy, Ali Didan, Isaac Spencer, Benhur Amanuel, Michael Millward, Mel Ziman, Elin Gray

Research outputs 2014 to 2021

BACKGROUND: PD-1 inhibitors are routinely used for the treatment of advanced melanoma. This study sought to determine whether PD-L1 expression on circulating tumor cells (CTCs) can serve as a predictive biomarker of clinical benefit and response to treatment with the PD-1 inhibitor pembrolizumab.

METHODS: Blood samples were collected from patients with metastatic melanoma receiving pembrolizumab, prior to treatment and 6-12 weeks after initiation of therapy. Multiparametric flow cytometry was used to identify CTCs and evaluate the expression of PD-L1.

RESULTS: CTCs were detected in 25 of 40 patients (63%). Patients with detectable PD-L1

CONCLUSION: Our results reveal the potential of …

A Comparative Study On User Satisfaction With The Information Resources And Library Facilities By Faculty Members In Three Agriculture Libraries, Abu, Futm, And Futo, In Nigeria, Lawal Mohammed Tukur, S. Kannan

Library Philosophy and Practice (e-journal)

The comparative study on user satisfaction with information resources, and library facilities by faculty members in Three Agriculture university Libraries: ABU, FUTM, AND FUTO in Nigeria; the respondents are faculty members, in Ahmadu Bello University Zaria, Federal University Technology Minna and Federal University Technology Owerri sampled by the researcher. The main objective of the study is to compare the information resources, and facilities of Agriculture University Libraries with view to examine the types of information resources, and facilities available and user’s satisfaction by the respondent’s Library. Simple random sampling was used in selecting the Agriculture University Libraries from …

An Appraisal Of Availability And Utilization Of Information Resources And Library Services By Undergraduate Students In Three Agriculture University Libraries In Northern Nigeria (Abu, Fuam, Futm), Lawal Mohammed Tukur, S. Kannan

Library Philosophy and Practice (e-journal)

The study appraisal of information resources and services in Agriculture University Libraries in Northern Nigeria; the respondents are undergraduate students in Ahmadu Bello University Zaria, Federal University Agriculture Makurdi, and Federal University Technology Minna sampled by the researcher. The main objective of the study is to evaluate information resources, services in Agriculture University Libraries in Northern Nigeria with view to examine the types of information resources, and services available, extent of utilization of the information resources by undergraduate students in Agriculture University Libraries in Northern Nigeria under study, while questionnaires were administered to the undergraduate students. The researcher …

Deciphering Functional Redundancy In The Human Microbiome., Liang Tian, Xu-Wen Wang, Ang-Kun Wu, Yuhang Fan, Jonathan Friedman, Amber Dahlin, Matthew K Waldor, George M. Weinstock, Scott T Weiss, Yang-Yu Liu

Faculty Research 2020

Although the taxonomic composition of the human microbiome varies tremendously across individuals, its gene composition or functional capacity is highly conserved - implying an ecological property known as functional redundancy. Such functional redundancy has been hypothesized to underlie the stability and resilience of the human microbiome, but this hypothesis has never been quantitatively tested. The origin of functional redundancy is still elusive. Here, we investigate the basis for functional redundancy in the human microbiome by analyzing its genomic content network - a bipartite graph that links microbes to the genes in their genomes. We find that this network exhibits several …

Diet And Successful Aging, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Learning Objectives:

Define successful aging

Understand the components of successful aging

Learn diets and dietary patterns for successful aging

Physical activity and successful aging

Resilient And Rapid Recovery Of Native Trout After Removal Of A Non-Native Trout, Phaedra E. Budy, Timothy Walsworth, Gary P. Thiede, Paul D. Thompson, Matthew D. Mckell, Paul B. Holden, Paul D. Chase, W. Carl Saunders

Watershed Sciences Faculty Publications

While the importance of reducing impacts of non-native species is increasingly recognized in conservation, the feasibility of such actions is highly dependent upon several key uncertainties including stage of invasion, size of the ecosystem being restored, and magnitude of the restoration activity. Here, we present results of a multi-year, non-native brown trout (Salmo trutta) removal and native Bonneville cutthroat trout (Oncorhynchus clarkii utah) response to this removal in a small tributary in the Intermountain West, United States. We monitored trout for 10 years prior to the onset of eradication efforts, which included 2 years of mechanical …

Evaluation Of Listeria Innocua Transfer From Personal Protective Equipment (Ppe) To The Plant Environment And Effective Sanitation Procedures To Control It In Dairy Processing Facilities, Karen Nieto

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Listeria monocytogenes can survive and grow under wet environmental conditions encountered in dairy facilities. Pasteurization of milk kills L. monocytogenes; however, recent listeriosis outbreaks have linked post-pasteurization contamination from the food environment to the final product. One of the sources of microbial contamination may include employees and their personal protective equipment (PPE), which often become in contact with equipment and food contact surfaces. To understand this issue, this study evaluates Listeria innocua, as a surrogate for Listeria monocytogenes, transfer from PPE to food products and surfaces encountered in dairy plants. Gloves, aprons, and boots were inoculated with L. …

Blenny Territoriality At Oyster Landing, North Inlet Estuary, South Carolina: Seasonal Patterns And Ecological Factors, Sydney Davis, Juliana Harding

Honors Theses

Temperate oyster reef blennies use oyster shells that are still articulated as habitat year round. During the breeding season when water temperatures are > 18-20°C, many species of blenny males use the oyster valves as nesting sites. Male blennies exhibit territorial behavior when guarding their nesting sites and can interact differently with conspecific and transient species. Striped blenny (Chasmodes bosquianus) and freckled blenny (Hypsoblennius ionthas) behavior was described from April 2020 to August 2020 at Oyster Landing, North Inlet estuary, South Carolina to quantify typical blenny behavior, general presence or absence of residents, and potential environmental parameters …

Infaunal Bivalve Density And Richness In North Inlet Estuary, South Carolina: Seasonal Patterns And Ecological Factors, Valerie M. Knowles, Juliana Harding

Honors Theses

Estuarine bivalves recruit to benthic habitats after the larvae are in the planktonic stage. The observed infaunal bivalve density relates to larval supply from adult reproduction during warmer months as well as larval and juvenile mortality post-recruitment. The purpose of this research was to examine annual and seasonal patterns of infaunal bivalve density and richness in the context of habitat water temperature and salinity. Cores were collected biweekly from Bly Creek in North Inlet estuary between January 2019 and February 2020. Temperatures ranged from 9-30 ºC and salinity ranged from ~17-36 psu. Bivalves were sieved out of the cores, counted, …

Ocean Acidification And Fish Respiration: A Study On The Anatomical, Physiological, And Behavioral Adaptations Of Fishes And Their Ability To Cope With Decreasing Seawater Ph, Mark P. Rogers

All HCAS Student Capstones, Theses, and Dissertations

Abstract

Fish stocks across the globe are increasingly being relied upon to supply the ever-growing human population with high quality protein and other nutrients. In addition to fishing pressure, stressors brought on by climate changes, including ocean acidification and hypoxic conditions, have the potential for providing substantial negative impacts on the efficiency of fish respiration, internal acid-base balance, and energy budgets. To meaningfully integrate the potential impacts of ocean acidification on fishes into management practices it is important to study the anatomical, physiological, and behavioral adaptations that enable fish to cope with decreasing seawater pH and how those mechanisms might …

Using Track Widths Of Loggerhead (Caretta Caretta) Sea Turtles As A Proxy For Predicting Nesting Characteristics, Kelly M. Detmer

All HCAS Student Capstones, Theses, and Dissertations

Global populations of sea turtles have suffered major declines over the past century. Thus, it is critical to determine accurate demographic parameters and abundance estimates to fill current data gaps and inform effective conservation and recovery strategies. Population models with greater complexity and predictive capacities are necessary to more accurately assess population trends and responses. This study examines the relationships between track width, female body size (as measured by straight and curved carapace lengths and widths), and nesting variables (chamber depth, clutch size, and hatching success) of loggerhead turtles (Caretta caretta) nesting in southeastern Florida. Track width was significantly …

Quality Of Life Among Injectable And Oral Disease-Modifying Therapy Users In The Pacific Northwest Multiple Sclerosis Registry., Tamela Stuchiner, Lindsay Lucas, Elizabeth Baraban, Kateri Spinelli, Chiayi Chen, Alden Smith, Lobat Hashemi, Stanley Cohan

Articles, Abstracts, and Reports

BACKGROUND: Nine oral disease-modifying therapies (DMTs) have been approved for the treatment of multiple sclerosis (MS) in the United States. Few studies have examined self-reported quality of life (QoL) and functional status outcomes among patients who switch to oral medications from injectable MS therapies. This study compares self-reported QoL and disability status between participants switching from injectable to oral DMTs, to those who stay on injectable DMTs continuously for the same time period.

METHODS: Longitudinal data were assessed from relapsing MS participants in the Pacific Northwest MS Registry completing a minimum of two surveys between 2012 and 2018 with a …

Systematic Comparison Of Sea Urchin And Sea Star Developmental Gene Regulatory Networks Explains How Novelty Is Incorporated In Early Development., Gregory A Cary, Brenna S Mccauley, Olga Zueva, Joseph Pattinato, William J R Longabaugh, Veronica F Hinman

Articles, Abstracts, and Reports

The extensive array of morphological diversity among animal taxa represents the product of millions of years of evolution. Morphology is the output of development, therefore phenotypic evolution arises from changes to the topology of the gene regulatory networks (GRNs) that control the highly coordinated process of embryogenesis. A particular challenge in understanding the origins of animal diversity lies in determining how GRNs incorporate novelty while preserving the overall stability of the network, and hence, embryonic viability. Here we assemble a comprehensive GRN for endomesoderm specification in the sea star from zygote through gastrulation that corresponds to the GRN for sea …

Early Life History Of Tarpon (Megalops Atlanticus) In South Carolina Estuaries: Assessment Of Juvenile Recruitment And Validity Of Aging And Back-Calculation Methods, Garrett M. Elmo

Electronic Theses and Dissertations

No abstract provided.

Residency, Diel Movement, And Tidal Patterns Of Large Juvenile Bull Sharks (Carcharhinus Leucas) In Winyah Bay, Sc, Jeremy Lee Arnt

Electronic Theses and Dissertations

No abstract provided.

An Artificial Intelligence-Based, Personalized Smartphone App To Improve Childhood Immunization Coverage And Timelines Among Children In Pakistan: Protocol For A Randomized Controlled Trial, Abdul Momin Kazi, Saad Ahmed Qazi, Sadori Khawaja, Nazia Ahsan, Rao Moueed Ahmed, Muhammad Ayub Khan Mughal, Hussain Kalimuddin, Yasir Rauf, Mehreen Raza, Saima Jamal

Department of Paediatrics and Child Health

Background: The immunization uptake rates in Pakistan are much lower than desired. Major reasons include lack of awareness, parental forgetfulness regarding schedules, and misinformation regarding vaccines. In light of the COVID-19 pandemic and distancing measures, routine childhood immunization (RCI) coverage has been adversely affected, as caregivers avoid tertiary care hospitals or primary health centers. Innovative and cost-effective measures must be taken to understand and deal with the issue of low immunization rates. However, only a few smartphone-based interventions have been carried out in low- and middle-income countries (LMICs) to improve RCI.
Objective: The primary objectives of this study are to …

The Fear Of Reptiles And How To Change It, Maxwell Lyman

Honors Projects

Reptile fear is prominent across many cultures. Anti-reptilian attitudes can lead to anti-conservation attitudes towards reptiles. Person-animal interaction has been shown to decrease fear desensitization and increase positive attitudes towards "unpopular" animals. My project demonstrates the effectiveness of live animal presentation in dispelling negative attitudes of reptiles. However, due to the sample size of the project, further research is highly suggested.

Effect Of Intrauterine Smoke Exposure On Microrna-15a Expression In Human Lung Development And Subsequent Asthma Risk., Sunita Sharma, Alvin T. Kho, Divya Chhabra, Kathleen Haley, Carrie A. Vyhlidal, R Gaedigk, J Steven Leeder, Kelan G. Tantisira, Benjamin Raby, Scott T. Weiss

Manuscripts, Articles, Book Chapters and Other Papers

Background: In utero smoke (IUS) exposure is associated with asthma susceptibility.

Objective: We sought to test the hypothesis that changes in miRNA expression by IUS exposure during human lung development is associated with asthma susceptibility.

Methods: Gene expression was profiled from 53 IUS unexposed and 51 IUS exposed human fetal lung tissues. We tested for the differential expression of miRNAs across post-conception age and by IUS using linear models with covariate adjustment. We tested the IUS-associated miRNAs for association with their gene expression targets using pair-wise inverse correlation. Using our mouse model, we investigated the persistence of the IUS-associated miRNA …

Structural Characterization And In Vitro Lipid Binding Studies Of Non-Specific Lipid Transfer Protein 1 (Nsltp1) From Fennel (Foeniculum Vulgare) Seeds, Mekdes Megeressa, Bushra Siraj, Shamshad Zarina, Aftab Ahmed

Pharmacy Faculty Articles and Research

Non-specific lipid transfer proteins (nsLTPs) are cationic proteins involved in intracellular lipid shuttling in growth and reproduction, as well as in defense against pathogenic microbes. Even though the primary and spatial structures of some nsLTPs from different plants indicate their similar features, they exhibit distinct lipid-binding specificities signifying their various biological roles that dictate further structural study. The present study determined the complete amino acid sequence, in silico 3D structure modeling, and the antiproliferative activity of nsLTP1 from fennel (Foeniculum vulgare) seeds. Fennel is a member of the family Umbelliferae (Apiaceae) native to southern Europe and the Mediterranean …

Integrated Management Of Feral Camels In Ngaanyatjarra Aboriginal Lands, Australia, Gordon Sanders, A. Knight

IGC Proceedings (1977-2023)

No abstract provided.

Effect Of Winter Closing Date And Spring Opening Date On The Dm Yield Of Perennial Ryegrass Cultivars, Emer Kennedy, M. O'Donovan, Mary Mcevoy

IGC Proceedings (1977-2023)

No abstract provided.

Effect Of Restricted Access Time To Pasture On Dairy Cow Milk Production, Grazing Behaviour And Dry Matter Intake, Emer Kennedy, M. O'Donovan

IGC Proceedings (1977-2023)

No abstract provided.

Endangered Bat Conservation In Wsu Woods, Olivia Norris, Josh Miller, Mitchell Link, Molly Nelson, Susan Fike

Runkle Woods Symposia

Our project focused on two endangered bat species in the Wright State Woods, the Indiana Bat and the Little Brown Bat. Our presentation covers topics such as general info, social behaviors, current threats, bat boxes, and conservation methods and goals.

Wright State Prairie Expansion, Kailani Sparrow, Reynold Kojo Papa Afful Ephraim

Runkle Woods Symposia

Our plan is to convert the northern edge of Wright State Woods along Kaufman Ave. into a prairie to provide a habitat for pollinator species that are declining due to habitat loss and other factors and to provide a scenic and educational area

Your Mom Isn’T Here To Pick Up After You… In Your Dorm Or On The Rest Of Campus, Madison Glass, Jonathan Hume, Mckenzie Stefanoff, Brandon Butler

Runkle Woods Symposia

Research and the litter that plagues the Wright State University Woods and what we can do about it as a campus community.

Wsu Woods Trail: Recreational Usage, Ada Compliance, Education, And Conservation, Amber Massie, Emily Ramey, Brooklyne Baldwin, Sarah (Sam) Potter, James (Tyler) Retherford

Runkle Woods Symposia

Our group will be discussing the Wright State University Woods. We will reveal tips on how to make the trails in the Wright State University Woods more accessible and ADA compliant as well as how to educate the community about wildlife and plant species in the woods.

The Honeysuckle Issue, Amanda Wibel, Madyson Vanhoose, Ava Jones, Katie Karr, Ashton Shephard

Runkle Woods Symposia

Our group will be discussing the Wright State University Woods. We will reveal tips on how to make the trails in the Wright State University Woods more accessible and ADA compliant as well as how to educate the community about wildlife and plant species in the woods.

Changes In Flowering Times In The Wsu Woods, James Runkle

Runkle Woods Symposia

Many studies have shown flowering patterns and other climate-based phenomena to be in flux. I wish to determine whether changes in first flowering dates can be shown in the Wright State University woods.