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2017

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Articles 91 - 120 of 8344

Full-Text Articles in Engineering

Material State Awareness For Composites Part Ii: Precursor Damage Analysis And Quantification Of Degraded Material Properties Using Quantitative Ultrasonic Image Correlation (Quic), Subir Patra, Sourav Banerjee Dec 2017

Material State Awareness For Composites Part Ii: Precursor Damage Analysis And Quantification Of Degraded Material Properties Using Quantitative Ultrasonic Image Correlation (Quic), Subir Patra, Sourav Banerjee

Faculty Publications

Material state awareness of composites using conventional Nondestructive Evaluation (NDE) method is limited by finding the size and the locations of the cracks and the delamination in a composite structure. To aid the progressive failure models using the slow growth criteria, the awareness of the precursor damage state and quantification of the degraded material properties is necessary, which is challenging using the current NDE methods. To quantify the material state, a new offline NDE method is reported herein. The new method named Quantitative Ultrasonic Image Correlation (QUIC) is devised, where the concept of microcontinuum mechanics is hybrid with the experimentally …


Effect Of Aggregate Mineralogy And Concrete Microstructure On Thermal Expansion And Strength Properties Of Concrete, Jinwoo An, S. Sonny Kim, Boo Hyun Nam, Stephan A. Durham Dec 2017

Effect Of Aggregate Mineralogy And Concrete Microstructure On Thermal Expansion And Strength Properties Of Concrete, Jinwoo An, S. Sonny Kim, Boo Hyun Nam, Stephan A. Durham

Civil Engineering Faculty Publications

Aggregate type and mineralogy are critical factors that influence the engineering properties of concrete. Temperature variations result in internal volume changes could potentially cause a network of micro-cracks leading to a reduction in the concrete's compressive strength. The study specifically studied the effect of the type and mineralogy of fine and coarse aggregates in the normal strength concrete properties. As performance measures, the coefficient of thermal expansion (CTE) and compressive strength were tested with concrete specimens containing different types of fine aggregates (manufactured and natural sands) and coarse aggregates (dolomite and granite). Petrographic examinations were then performed to determine the …


Spatial Transferability Assessment Of A Composite Walkability Index: The Pedestrian Index Of The Environment (Pie), Gabriel Lefebvre-Ropars, Catherine Morency, Patrick A. Singleton, Kelly J. Clifton Dec 2017

Spatial Transferability Assessment Of A Composite Walkability Index: The Pedestrian Index Of The Environment (Pie), Gabriel Lefebvre-Ropars, Catherine Morency, Patrick A. Singleton, Kelly J. Clifton

Civil and Environmental Engineering Faculty Publications and Presentations

This paper analyzes the transferability of a composite walkability index, the Pedestrian Index of the Environment (PIE), to the Greater Montréal Area (GMA). The PIE was developed in Portland, Oregon, and is based on proprietary data. It combines six urban form variables into a score ranging from 20 to 100. The measure introduces several methodological refinements which have not been applied concurrently in previous efforts: a wide coverage of the different dimensions of the urban form, together with the use of a distance-based decay function and modelling-based weighing of the variables.


Micro-Architectured Metamaterials: Design And Analysis, Li Ai Dec 2017

Micro-Architectured Metamaterials: Design And Analysis, Li Ai

Mechanical Engineering Research Theses and Dissertations

Metamaterials are engineered materials with unusual properties deriving mainly from their micro-architectures rather than composition. They have attracted increasing attention owing to their tailorable multi-functional properties that cannot be exhibited by naturally-occurring or traditionally-manufactured materials. Materials with a negative Poisson’s ratio (PR) and materials with a non-positive coefficient of thermal expansion (CTE) are examples of mechanical metamaterials. In this dissertation, metamaterials with negative Poisson’s ratios and negative coefficients of thermal expansion are designed using both heuristic approaches and topology optimization methods.

Firstly, based on a star-shaped re-entrant structure, three two-dimensional (2-D) periodic cellular materials are developed, which can be tailored …


Material State Awareness For Composites Part I: Precursor Damage Analysis Using Ultrasonic Guided Coda Wave Interferometry (Cwi), Subir Patra, Sourav Banerjee Dec 2017

Material State Awareness For Composites Part I: Precursor Damage Analysis Using Ultrasonic Guided Coda Wave Interferometry (Cwi), Subir Patra, Sourav Banerjee

Faculty Publications

Detection of precursor damage followed by the quantification of the degraded material properties could lead to more accurate progressive failure models for composite materials. However, such information is not readily available. In composite materials, the precursor damages—for example matrix cracking, microcracks, voids, interlaminar pre-delamination crack joining matrix cracks, fiber micro-buckling, local fiber breakage, local debonding, etc.—are insensitive to the low-frequency ultrasonic guided-wave-based online nondestructive evaluation (NDE) or Structural Health Monitoring (SHM) (~100–~500 kHz) systems. Overcoming this barrier, in this article, an online ultrasonic technique is proposed using the coda part of the guided wave signal, which is often neglected. Although …


A Low Power High Speed Mobile Memory I/O Interface Using Reconfigurable Multi-Band Multi-Modulation Signaling, Yue Yu Dec 2017

A Low Power High Speed Mobile Memory I/O Interface Using Reconfigurable Multi-Band Multi-Modulation Signaling, Yue Yu

Electrical Engineering Theses and Dissertations

This research mainly focuses on the design of a novel memory I/O interface with high bandwidth and high energy-efficient for mobile computing systems in order to dramatically enhance the circuit and system bandwidth and power efficiency. The proposed memory I/O interface, exploiting multi-modulation and multi-band signaling, is capable of supporting simultaneous bidirectional data transition of 4 separate data streams across a single-ended off-chip transmission line to achieve both high speed data rate and low power consumption. This multi-band multi-modulation interface (MMI) consists of multiple RF-band transceivers which utilize ASK modulation, and baseband transceivers which utilize 4-PAM modulation to increase the …


Design, Fabrication, And Demonstration Of Square Holey Dielectric Thz Waveguides, Nafiseh Aflakian Dec 2017

Design, Fabrication, And Demonstration Of Square Holey Dielectric Thz Waveguides, Nafiseh Aflakian

Electrical Engineering Theses and Dissertations

A variety of novel dielectric THz waveguides were demonstrated to increase a channel capacity in a chip-to-chip communication system. Square holey cladding dielectric THz waveguides were designed, fabricated, and characterized. The single material holey cladding waveguide is low loss and easy to fabricate compared to doped core fibers. The square geometry supports two states of polarization with minimum cross-talk for polarization division multiplexing applications. Simulations show the waveguide supports two states of polarization across the frequency range of 180 GHz to 360 GHz. In addition, simulations show good mode isolation and low bending losses. Holey cladding square waveguide was fabricated …


Implementation Of Switching Circuit Models As Vector Space Transformations, David Kebo Houngninou Dec 2017

Implementation Of Switching Circuit Models As Vector Space Transformations, David Kebo Houngninou

Computer Science and Engineering Theses and Dissertations

Modeling of switching circuits is the foundation for many Electronic Design Automation (EDA) tasks and is commonly used at various phases of the design flow for tasks such as simulation, justification, and other analyses. State-of-the-art simulation tools are based on discrete event algorithms using switching algebraic models and are highly optimized and mature. Symbolic simulation may also be implemented using a discrete event approach, or other approaches based on extracted functional models. The common foundation of modern simulation tools is that of a switching or Boolean algebraic model that may be augmented with timing information. Justification using switching circuit models …


Moving Bed Biofilm Reactors: Evaluation Of Geometry, Attachment Surface Material And Biofilm Populations On The Uptake Of Ammonia And Synthetic Organic Contaminants In Wastewater., Patrick D. Mclee Dec 2017

Moving Bed Biofilm Reactors: Evaluation Of Geometry, Attachment Surface Material And Biofilm Populations On The Uptake Of Ammonia And Synthetic Organic Contaminants In Wastewater., Patrick D. Mclee

Civil Engineering ETDs

Plastic biofilm carriers are used in biological wastewater treatment to encourage the attachment and retention of microorganisms that metabolize pollutants. The following research was conducted to better understand how different characteristics of the biofilm carrier affect the treatment performance of the attached biofilms in moving bed bioreactors. Lab scale reactors were used in this study to grow nitrifying biofilms in reactors with contrasting and controlled conditions. The effect of surface geometry on nitrification performance was evaluated by testing commercially available moving bed bioreactor media that contrast in physical design, and by varying operational parameters. Additionally, mature biofilm from a similar …


Brain Motion, Deformation, And Potential Injury During Soccer Heading, Charles F. Babbs Dec 2017

Brain Motion, Deformation, And Potential Injury During Soccer Heading, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

This paper addresses the problem of what is happening physically inside the skull during head-ball contact. Mathematical models based upon Newton’s laws of motion and numerical methods are used to create animations of brain motion and deformation inside the skull.

Initially a 1 cm gap filled with cerebrospinal fluid (CSF) separates the brain from the rigid skull in adults and older children. Whole head acceleration induces a pulse of artificial gravity within the skull. Because brain density differs slightly from that of CSF, the brain accelerates and strikes the inner aspect of the skull, undergoing viscoelastic deformation, ranging from 1 …


Quantifying The Effect Of Construction Site Factors On Concrete Quality, Costs And Production Rates, Jorge L. Santamaria Dec 2017

Quantifying The Effect Of Construction Site Factors On Concrete Quality, Costs And Production Rates, Jorge L. Santamaria

Civil Engineering ETDs

Factors affecting concrete can be categorized as structured factors or unstructured factors. The first group of factors consists of those related to the production process of concrete including water-cement ratio, properties of raw materials and mix proportions. Unstructured factors or construction site factors are related to labor skills and local conditions during the construction process of a project. Concrete compressive strength as a quality metric, costs and production rates may be affected significantly by such factors while performing concrete operations at the jobsite. Several prior studies have investigated the effect of structured factors on concrete. However literature is limited regarding …


Outer Space: A Steam Voyage, Jancy Mcphee Dec 2017

Outer Space: A Steam Voyage, Jancy Mcphee

The Transdisciplinary STEAM+ Journal

SciArt Exchange offers multi-disciplinary art contests, artwork events, consulting, training and community resources to support science and technology education, collaboration, and innovation. Using a science-integrated- with-art approach, SciArt Exchange supports, prepares, and convenes people of all ages, backgrounds and affiliations to discuss and potentially solve space, science, and technology challenges. This field note shares the Humans in Space Art Program and the Project Mars Competition.


3d Printing – An Insider’S Perspective, Siddharth Sah Dec 2017

3d Printing – An Insider’S Perspective, Siddharth Sah

The Transdisciplinary STEAM+ Journal

The 3D printing market globally is still at its infancy, - or some might argue that there isn’t really a market yet. The knowledge of 3D printing design is still largely limited to engineering design – not product design. At MakeWhale, we are constantly pushing the boundaries of the application of 3D printing technology to consumer products resulting in a beautiful mix of technology and art.


Mitochondrial Dynamics And Respiration Within Cells With Increased Open Pore Cytoskeletal Meshes, David H. Jang, Sarah C. Seeger, Martha E. Grady, Frances S. Shofer, David M. Eckmann Dec 2017

Mitochondrial Dynamics And Respiration Within Cells With Increased Open Pore Cytoskeletal Meshes, David H. Jang, Sarah C. Seeger, Martha E. Grady, Frances S. Shofer, David M. Eckmann

Mechanical Engineering Faculty Publications

The cytoskeletal architecture directly affects the morphology, motility, and tensional homeostasis of the cell. In addition, the cytoskeleton is important for mitosis, intracellular traffic, organelle motility, and even cellular respiration. The organelle responsible for a majority of the energy conversion for the cell, the mitochondrion, has a dependence on the cytoskeleton for mobility and function. In previous studies, we established that cytoskeletal inhibitors altered the movement of the mitochondria, their morphology, and their respiration in human dermal fibroblasts. Here, we use this protocol to investigate applicability of power law diffusion to describe mitochondrial locomotion, assessment of rates of fission and …


Development Of A Curriculum Analysis And Simulation Library With Applications In Curricular Analytics, Michael S. Hickman Dec 2017

Development Of A Curriculum Analysis And Simulation Library With Applications In Curricular Analytics, Michael S. Hickman

Electrical and Computer Engineering ETDs

Higher education institutions are currently investing significant resources in attempts to improve student success by improving instruction quality, implementing tutoring programs, and providing other services to help students. While these are all worth- while, one area that tends to be overlooked is the structure of the curricula that are offered. When viewing curricula as data, or more specifically, a graph, it is intuitive to see how its structure can influence a student’s ability to move through it. How- ever, there are currently no tools to analyze a curriculum’s structural properties and how they might affect student success. This thesis describes …


Identification Of Prognostic Cancer Biomarkers Through The Application Of Rna-Seq Technologies And Bioinformatics, Nathan Wong Dec 2017

Identification Of Prognostic Cancer Biomarkers Through The Application Of Rna-Seq Technologies And Bioinformatics, Nathan Wong

McKelvey School of Engineering Graduate Student Theses & Dissertations

MicroRNAs (miRNAs) are short single-stranded RNAs that function as the guide sequence of the post-transcriptional regulatory process known as the RNA-induced silencing complex (RISC), which targets mRNA sequences for degradation through complementary binding to the guide miRNA. Changes in miRNA expression have been reported as correlated with numerous biological processes, including embryonic development, cellular differentiation, and disease manifestation. In the latter case, dysregulation has been observed in response to infection by human papillomavirus (HPV), which has also been established as both oncogenic in cervical cancers and oropharyngeal cancers and favorable for overall patient survival after tumor formation. The identification of …


Multi-Scale Studies To Develop A Holistic Understanding Of Solid Fuel Combustion At Residential Scale, Sameer Patel Dec 2017

Multi-Scale Studies To Develop A Holistic Understanding Of Solid Fuel Combustion At Residential Scale, Sameer Patel

McKelvey School of Engineering Graduate Student Theses & Dissertations

Nearly 3 billion people rely on solid fuels for their cooking and heating needs, classifying them as “energy poor”. This poverty can be attributed to several factors, including a lack of resources (fuel), inefficient infrastructure (production and distribution), limited purchasing power (poverty), and ill-devised policies. Solid fuels, such as biomass, coal, and dung cakes, are burned in inefficient cookstoves. They generate products of incomplete combustion (PIC), such as CO, particulate matter (PM), and CH4, causing household air pollution (HAP) whose adverse impacts on both health and the environment have been well established.

HAP causes diseases such as chronic obstructive pulmonary …


Functional Bio-Nano Hybrids Through A Precise Control Of Interfacial Interactions At The Nanoscale, Sirimuvva Tadepalli Dec 2017

Functional Bio-Nano Hybrids Through A Precise Control Of Interfacial Interactions At The Nanoscale, Sirimuvva Tadepalli

McKelvey School of Engineering Graduate Student Theses & Dissertations

During the course of evolution, proteins have evolved to perform exquisite functions including structural support, signal transduction, actuation, sensing, catalysis, trafficking, gating, light-harvesting, charge transfer, molecular recognition, self-assembly, self-organization, or combinations of two or more of these functions. A precise control and manipulation of the structure and function of proteins is conceivable with the advent of nanotechnology, which has facilitated the integration of nanomaterials with functional biomolecules to realize bio-nano hybrids with synergistically enhanced functionalities.

At the genesis of bionanotechnology, a paucity in the fundamental understanding of the bio-nano interfaces is a grave impediment to the progress of the field. …


The Inter-Laminar Shearing Effect On Wrinkle Development In Composite Forming Processes, David Sundquist Dec 2017

The Inter-Laminar Shearing Effect On Wrinkle Development In Composite Forming Processes, David Sundquist

McKelvey School of Engineering Graduate Student Theses & Dissertations

Composite materials are becoming prevalent in aerospace industries as the uniqueness of the composite structure allows the composite to be tailored specifically for individual applications. Many fabrication techniques produce defects in composite parts such as wrinkles, fiber waviness, fiber misalignment, and porosity. The driving mechanisms behind these defects occurring during forming processes are not fully understood and, thus, characterization formation of these defects in a uncured state is beneficial to optimize composite processing. This work primarily investigated the influence of how uncured pre-impregnated carbon ply properties affect the wrinkling behavior of a composite laminates. Several factors affecting composite ply forming …


Development Of In Vitro Drug Screening Platforms Using Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells, Yosuke Kurokawa Dec 2017

Development Of In Vitro Drug Screening Platforms Using Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells, Yosuke Kurokawa

McKelvey School of Engineering Graduate Student Theses & Dissertations

Drug-induced cardiotoxicity is a critical challenge in the development of new drugs. Since the advent of human pluripotent stem cell-derived cardiomyocytes (CMs), researchers have explored ways to utilize these cells for in vitro preclinical drug screening applications. One area of interest is microphysiological systems (i.e. organ-on-a-chip), which aims to create more complex in vitro models of human organ systems, thus improving drug response predictions. In this dissertation, we investigated novel analysis methods and model platforms for detecting drug-induced cardiotoxicity using human induced pluripotent stem cell (iPSC)-derived cardiovascular cells.

First, we utilized human iPSC-derived CMs (iPS-CMs) to establish optical methods of …


Extrinsic And Intrinsic Control Of Integrative Processes In Neural Systems, Anirban Nandi Dec 2017

Extrinsic And Intrinsic Control Of Integrative Processes In Neural Systems, Anirban Nandi

McKelvey School of Engineering Graduate Student Theses & Dissertations

At the simplest dynamical level, neurons can be understood as integrators. That is, neurons accumulate excitation from afferent neurons until, eventually, a threshold is reached and they produce a spike. Here, we consider the control of integrative processes in neural circuits in two contexts. First, we consider the problem of extrinsic neurocontrol, or modulating the spiking activity of neural circuits using stimulation, as is desired in a wide range of neural engineering applications. From a control-theoretic standpoint, such a problem presents several interesting nuances, including discontinuity in the dynamics due to the spiking process, and the technological limitations associated with …


The Effect Of Z-Binding Yarns On The Electrical Properties Of 3d Woven Composites, Mohamed Nasr Saleh, Arief Yudhanto, Gilles Lubineau, Constantinos Soutis Dec 2017

The Effect Of Z-Binding Yarns On The Electrical Properties Of 3d Woven Composites, Mohamed Nasr Saleh, Arief Yudhanto, Gilles Lubineau, Constantinos Soutis

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Electrical resistance monitoring (ERM) has been used to study the effect of the z-binding yarns on the initial electrical resistance (ER) and its change of three architectures of 3D woven carbon fiber composites namely (orthogonal "ORT", layer-to-layer "LTL" and angle interlock "AI") when tested in tension. Specimens are loaded in on-axis "warp" and off-axis "45°" directions. In situ ERM is achieved using the four-probe technique. Monotonic and cyclic "load/unload" tests are performed to investigate the effect of piezo-resistivity and residual plasticity on resistance variation. The resistance increases for the off-axis loaded specimens (∼90%) is found to be higher than that …


The Future Of Nuclear Security: A Medical Physicist’S Perspective, Katharine E. Thomson Dec 2017

The Future Of Nuclear Security: A Medical Physicist’S Perspective, Katharine E. Thomson

International Journal of Nuclear Security

Planning for the future of nuclear security is a vital and complex task, requiring cooperation and contribution from many disciplines and industries. This diversity of expertise should include the medical sector, which faces many of the same challenges as the nuclear industry: controlling access to dangerous material, creating a strong security culture, cooperating with the wider world and engaging the public.

Medical physicists, of which the author is one, oversee all aspects of small-scale radiation use. This paper discusses three key areas increasingly important to both medical and nuclear uses of radioactive materials: public engagement, prevention of nuclear and radiological …


The Future Of Nuclear Security In Moroccan Territory After The Creation Of The New Moroccan Agency Of Nuclear And Radiological Safety And Security: Opportunities And Challenges, Amal Touarsi, Amina Kharchaf Dec 2017

The Future Of Nuclear Security In Moroccan Territory After The Creation Of The New Moroccan Agency Of Nuclear And Radiological Safety And Security: Opportunities And Challenges, Amal Touarsi, Amina Kharchaf

International Journal of Nuclear Security

Nowadays, a security regime for protecting nuclear and radiological material—providing an intelligent national regulatory institution and establishing national security laws—is necessary in order for a state to ensure security of nuclear and radiological materials used within its borders.

This paper focuses on discussing the opportunities and challenges facing the future of nuclear security after the creation of the new Moroccan Agency of Nuclear and Radiological Safety and Security.


System Characterizations And Optimized Reconstruction Methods For Novel X-Ray Imaging, Huifeng Guan Dec 2017

System Characterizations And Optimized Reconstruction Methods For Novel X-Ray Imaging, Huifeng Guan

McKelvey School of Engineering Graduate Student Theses & Dissertations

In the past decade there have been many new emerging X-ray based imaging technologies developed for different diagnostic purposes or imaging tasks. However, there exist one or more specific problems that prevent them from being effectively or efficiently employed. In this dissertation, four different novel X-ray based imaging technologies are discussed, including propagation-based phase-contrast (PB-XPC) tomosynthesis, differential X-ray phase-contrast tomography (D-XPCT), projection-based dual-energy computed radiography (DECR), and tetrahedron beam computed tomography (TBCT). System characteristics are analyzed or optimized reconstruction methods are proposed for these imaging modalities. In the first part, we investigated the unique properties of propagation-based phase-contrast imaging technique …


System Optimization And Iterative Image Reconstruction In Photoacoustic Computed Tomography For Breast Imaging, Yang Lou Dec 2017

System Optimization And Iterative Image Reconstruction In Photoacoustic Computed Tomography For Breast Imaging, Yang Lou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoacoustic computed tomography(PACT), also known as optoacoustic tomography (OAT), is an emerging imaging technique that has developed rapidly in recent years. The combination of the high optical contrast and the high acoustic resolution of this hybrid imaging technique makes it a promising candidate for human breast imaging, where conventional imaging techniques including X-ray mammography, B-mode ultrasound, and MRI suffer from low contrast, low specificity for certain breast types, and additional risks related to ionizing radiation. Though significant works have been done to push the frontier of PACT breast imaging, it is still challenging to successfully build a PACT breast imaging …


Image Reconstruction Of The Speed Of Sound And Initial Pressure Distributions In Ultrasound Computed Tomography And Photoacoustic Computed Tomography, Thomas Paul Matthews Dec 2017

Image Reconstruction Of The Speed Of Sound And Initial Pressure Distributions In Ultrasound Computed Tomography And Photoacoustic Computed Tomography, Thomas Paul Matthews

McKelvey School of Engineering Graduate Student Theses & Dissertations

Ultrasound computed tomography (USCT) and photoacoustic computed tomography (PACT) are two emerging imaging modalities that have a wide range of potential applications from pre-clinical small animal imaging to cancer screening in human subjects. USCT is typically employed to measure acoustic contrasts, including the speed of sound (SOS) distribution, while PACT typically measures optical contrasts or some related quantity such as the initial pressure distribution. Their complementary contrasts and similar implementations make USCT and PACT a natural fit for a hybrid imaging system. Still, much work remains to realize this promise. First, USCT image reconstruction methods based on the acoustic wave …


Reconstruction Algorithms For Novel Joint Imaging Techniques In Pet, Homayoon Ranjbar Dec 2017

Reconstruction Algorithms For Novel Joint Imaging Techniques In Pet, Homayoon Ranjbar

McKelvey School of Engineering Graduate Student Theses & Dissertations

Positron emission tomography (PET) is an important functional in vivo imaging modality with many clinical applications. Its enormously wide range of applications has made both research and industry combine it with other imaging modalities such as X-ray computed tomography (CT) or magnetic resonance imaging (MRI). The general purpose of this work is to study two cases in PET where the goal is to perform image reconstruction jointly on two data types.

The first case is the Beta-Gamma image reconstruction. Positron emitting isotopes, such as 11C, 13N, and 18F, can be used to label molecules, and tracers, such …


Binding Affinity And Specificity Of Sh2 Domain Interactions In Receptor Tyrosine Kinase Signaling Networks, Tom Ronan Dec 2017

Binding Affinity And Specificity Of Sh2 Domain Interactions In Receptor Tyrosine Kinase Signaling Networks, Tom Ronan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Receptor tyrosine kinase (RTK) signaling mechanisms play a central role in intracellular signaling and control development of multicellular organisms, cell growth, cell migration, and programmed cell death. Dysregulation of these signaling mechanisms results in defects of development and diseases such as cancer. Control of this network relies on the specificity and selectivity of Src Homology 2 (SH2) domain interactions with phosphorylated target peptides. In this work, we review and identify the limitations of current quantitative understanding of SH2 domain interactions, and identify severe limitations in accuracy and availability of SH2 domain interaction data. We propose a framework to address some …


Impact Of Flow Direction On Local Flow Behavior In Biologically-Inspired Flow Passages, Derrick Dewayne Herrin Dec 2017

Impact Of Flow Direction On Local Flow Behavior In Biologically-Inspired Flow Passages, Derrick Dewayne Herrin

Honors College Theses

ABSTRACT

A computational fluid dynamics model was utilized to study the effect of flow direction on local flow behavior in biologically-inspired microscale flow networks. Biologically-inspired flow networks have been found to offer numerous advantages when compared with parallel flow networks, particularly in thermal management applications. Flow behavior was examined for a range of bifurcation angles and laminar inlet Reynolds numbers. The computational model was validated with existing theoretical solutions and verified for grid independence. As the bifurcation angle increased, the pressure drop, and thus pumping power, across the biologically-inspired flow networks increased. In addition, as the inlet Reynolds number increased, …