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2017

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Articles 1981 - 2010 of 8353

Full-Text Articles in Engineering

Modelling Catalytic Structures With Python And Ase, Tommie L. Day, Peilin Liao, Pilsun Yoo Aug 2017

Modelling Catalytic Structures With Python And Ase, Tommie L. Day, Peilin Liao, Pilsun Yoo

The Summer Undergraduate Research Fellowship (SURF) Symposium

Voltaic cells hold great potential as a source of clean electricity generation. These fuel sources are more efficient than combustion engines, and they do not produce environmentally harmful by-products. The electrochemical reaction which occurs within the cell is typically catalyzed by platinum, which increases the cost. The search for a better performing, less expensive catalyst is hindered by the lack of a complete, predictive theory of catalysis. Using Quantum Espresso and the Atomic Simulation Environment library for Python, we created a tool for nanoHUB.org which can visually and computationally model catalytic surfaces. This tool can simulate nanoparticles and metallic surfaces …

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Separation Of Rare Earth Elements From Aluminum Using Ion-Exchange Chromatography, Shabrina Nurfitriani, Hoon Choi, Nien-Hwa Linda Wang Aug 2017

Separation Of Rare Earth Elements From Aluminum Using Ion-Exchange Chromatography, Shabrina Nurfitriani, Hoon Choi, Nien-Hwa Linda Wang

The Summer Undergraduate Research Fellowship (SURF) Symposium

Demand of rare earth elements (REEs) has increased tremendously due to their key roles in electronics and emerging technology. Recently, new technology was developed at Purdue to extract REEs from coal fly ash. This study is focused on the separation of aluminum ions (Al), a major impurity in the extract, from REEs. The goal is to test the feasibility of an ion-exchange process for separating REEs from a highly-concentrated Al solution. First, we reduced the resin particle size to decrease dispersion and diffusion effects, to increase resin productivity, and to reduce the amounts of REEs and the ion-exchange resin required …

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Using High Resolution Images To Investigate Fatigue Crack Initiation Of Alloys At The Microstructural Level, Michael P. Reinhold, Alberto Mello, Michael Sangid Aug 2017

Using High Resolution Images To Investigate Fatigue Crack Initiation Of Alloys At The Microstructural Level, Michael P. Reinhold, Alberto Mello, Michael Sangid

The Summer Undergraduate Research Fellowship (SURF) Symposium

Microstructural features within a material dictate the material’s mechanical behavior and lead to localized strains as the sample is deformed. In order to further understand structural failure, an improved understanding of how microstructural features influence failure is necessary. Fatigue is one common mode of failure for aerospace applications, and a better understanding of the conditions of crack initiation can provide information that ultimately may increase longevity of aerospace systems. This paper investigates the hypothesis that fatigue crack initiation for a cyclically loaded sample is correlated to areas of higher localized strain. The experiment was conducted using a Ti-6Al-4V sample subjected …

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Carbon Removal And Optoelectronic Property Tuning In Copper Arsenic Sulfide Thin Films Through Ligand Exchange And Alloying, Louis R. Schroeder, Scott Mcclary, Rakesh Agrawal Aug 2017

Carbon Removal And Optoelectronic Property Tuning In Copper Arsenic Sulfide Thin Films Through Ligand Exchange And Alloying, Louis R. Schroeder, Scott Mcclary, Rakesh Agrawal

The Summer Undergraduate Research Fellowship (SURF) Symposium

Solution processed thin film solar cells are attractive alternatives to conventional energy sources due to low waste generation, flexibility in substrate choice, and scalability. The novel semiconductor Cu3AsS4 in the enargite phase has a near ideal band gap of 1.4 eV and has earth abundant constituent elements; yet single-junction solar cells have yielded low efficiencies due to a secondary carbonaceous phase present, among other issues. This carbonaceous phase may be eliminated by exchanging the carbonaceous ligands with molecular metal chalcogenides. To characterize the ligand exchanged particles, UV-Vis-NIR spectroscopy, Raman spectroscopy, X-ray diffraction, scanning electron microscopy, energy dispersive X-ray spectroscopy, and …

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Irradiation-Induced Nanocluster Evolution, Didier Ishimwe, Matthew J. Swenson, Janelle P. Wharry Aug 2017

Irradiation-Induced Nanocluster Evolution, Didier Ishimwe, Matthew J. Swenson, Janelle P. Wharry

The Summer Undergraduate Research Fellowship (SURF) Symposium

Oxide dispersion strengthened steel (ODS) and commercial ferritic-martensitic (F-M) alloys are widely accepted candidate structural materials for designing advanced nuclear reactors. Nanoclusters embedded in the steel matrix are key microstructural features of both alloy types. Irradiation from nuclear fusion and fission affects the morphology of these nanoparticles, altering the performance of the alloys and potentially decreasing their usable lifetime. Thus, it is important to understand the effect of irradiation on these nanoparticles in order to predict long-term nuclear reactor performance. It was found that the evolution of nanoclusters in each material is different depending on the experimental irradiation parameters. The …

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Full-Water Column Turbulence Parameterization Of Stratified Waters In Southern Lake Michigan, Kyla A. Prendergast, Cary D. Troy, David Cannon Aug 2017

Full-Water Column Turbulence Parameterization Of Stratified Waters In Southern Lake Michigan, Kyla A. Prendergast, Cary D. Troy, David Cannon

The Summer Undergraduate Research Fellowship (SURF) Symposium

Full water column mean flow and turbulence structure was characterized at two stratified locations in Lake Michigan (a. Muskegon, MI; b. Michigan City, IN) in order to better understand the filtration potential of invasive quagga mussels. Invasive quagga mussels in Lake Michigan are filter feeders and can dramatically alter clarity as well as the biological/chemical characteristics of the water column. This filtering capacity is highly contingent on turbulence characteristics throughout the water column, which is poorly understood in the Great Lakes. Using velocity, temperature, and turbulence data collected from these locations, the structure of the water column turbulence was modeled …

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Thermal Characterization Of Magnetic Components, Jiazhou Zhong, Veda Samhitha Duppalli, Scott D. Sudhoff Professor Aug 2017

Thermal Characterization Of Magnetic Components, Jiazhou Zhong, Veda Samhitha Duppalli, Scott D. Sudhoff Professor

The Summer Undergraduate Research Fellowship (SURF) Symposium

Thermal limits are crucial constraints in the design of power magnetic components. As the power density of magnetic components continues to increase, cooling becomes more critical. Our research focuses on solving for the amount of cooling needed for a particular magnetic component. During the research process, a low-velocity wind tunnel designed and built from the ground up is used to form uniform and controlled conditions for the test components. Thermal Equivalent Circuit (TEC) and parameter identification techniques are used in conjunction to yield temperature distribution results. The expected result is temperature data on various areas of the component under different …

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Operation Of The T-100 Hall Effect Thruster, Glynn Smith, Omar Dary, Alexey Shashurin Aug 2017

Operation Of The T-100 Hall Effect Thruster, Glynn Smith, Omar Dary, Alexey Shashurin

The Summer Undergraduate Research Fellowship (SURF) Symposium

The introduction of Hall Effect Thrusters from the former Soviet Union to the United States generated considerable interest in using the propulsion system aboard Western spacecraft. The established programs evaluated the SPT-100, and TAL-55 Hall Effect Thrusters for efficiency, lifetime, and performance characteristics. The T-100 model garnered only minor interest during this time compared with the same generation counterparts, the SPT-100, and TAL-55. This gap in knowledge on the efficiency, and performance of the T-100 warrants investigation into the design, and operation of the thruster. Operational characteristics will be measured on a restored T-100 Hall Thruster, using argon as a …

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Three-Dimensional Microfluidic Tumor Vascular Model For Investigating Breast Cancer Metastasis, Anastasiia Vasiukhina, Brian H. Jun, Luis Solorio, Pavlos P. Vlachos Aug 2017

Three-Dimensional Microfluidic Tumor Vascular Model For Investigating Breast Cancer Metastasis, Anastasiia Vasiukhina, Brian H. Jun, Luis Solorio, Pavlos P. Vlachos

The Summer Undergraduate Research Fellowship (SURF) Symposium

Metastasis is one of the primary reasons for the high mortality rates in female patients diagnosed with breast cancer. It involves the migration of cancer cells into the circulatory system allowing for the dissemination of cancer cells in distal tissues. Understanding the major processes that occur in cells and tissues during metastasis can help improve currently existing therapeutic methods. In order to understand such mechanisms, developing physiologically relevant tissue models is crucial. Advancements in microfluidics have led to the fabrication of 3D culture models with shear stress gradients and flow control that can recapitulate aspects of the tumor microenvironment in …

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Development Of An Unmanned Aerial System For Radiation Mapping In Nuclear Facilities, Jackson Ball, Guangying Jiang, Robert Bean Aug 2017

Development Of An Unmanned Aerial System For Radiation Mapping In Nuclear Facilities, Jackson Ball, Guangying Jiang, Robert Bean

The Summer Undergraduate Research Fellowship (SURF) Symposium

Efficiently planning a decontamination and decommissioning (D&D) operation at a nuclear facility requires detailed information on the conditions present. In the wake of a disaster, or just years of abandonment, a facility’s layout may have dramatically changed, making previous facility drawings unreliable, and radioactive particles may have been spread over the site, contaminating equipment and structures. Rather than tasking workers with mapping and characterizing the contamination, which can take days or weeks and poses a health and safety risk to the workers, mapping the site and locating contamination can be done remotely by an unmanned aerial vehicle (UAV), which would …

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Localized Immunosuppression Therapy For Islet Cell Encapsulation, Madeline Mclaughlin, Clarissa Stephens, Sherry Voytik-Harbin Aug 2017

Localized Immunosuppression Therapy For Islet Cell Encapsulation, Madeline Mclaughlin, Clarissa Stephens, Sherry Voytik-Harbin

The Summer Undergraduate Research Fellowship (SURF) Symposium

Type 1 diabetes, an autoimmune disease in which the body’s immune system destroys the insulin-producing beta cells necessary for managing a person’s blood glucose levels, affects 1.25 million Americans. A potential treatment for this disease is islet cell transplantation where Islets of Langerhans, containing the beta cells, are transplanted from a normal donor to a diabetic recipient to regulate blood glucose levels and provide insulin independence. Similar to whole organ transplantation, immune modulation through immunosuppression therapy is necessary for successful transplantation of islets without rejection. However, long-term systemic immunosuppression therapy can be toxic to the patient and the islets. Because …

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Assessing The Hydraulics Of Water Heaters By Adding Fluoride As A Tracer To Inform Its Overall Effect On Water Quality, Christian A. Guerrero, William Schmidt, Antoine Aubeneau, Amisha D. Shah Aug 2017

Assessing The Hydraulics Of Water Heaters By Adding Fluoride As A Tracer To Inform Its Overall Effect On Water Quality, Christian A. Guerrero, William Schmidt, Antoine Aubeneau, Amisha D. Shah

The Summer Undergraduate Research Fellowship (SURF) Symposium

As residential water heaters are the primary source of waterborne disease outbreaks in the U.S. there is a need to better understand how they are contributing to decreased water quality in buildings. Previous work has indicated that intermittent stagnation, low disinfection residual and operation temperatures promote the growth of pathogens in water heaters. The overall effect of hydrodynamics of water heaters on these factors remains unclear. Therefore, a tracer study was performed to determine the effect of and characterize hydraulics of the typical residential water heater on water quality. Controlling temperature and flow rate, a pilot-scale hot water system (50 …

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Acoustic Analysis Of Vocalizations For Detecting Separation Anxiety In Dogs, Karina Sequera, Nan Kong, Niwako Ogata Aug 2017

Acoustic Analysis Of Vocalizations For Detecting Separation Anxiety In Dogs, Karina Sequera, Nan Kong, Niwako Ogata

The Summer Undergraduate Research Fellowship (SURF) Symposium

Separation anxiety in dogs is a clinical condition in which a dog develops an intense dependence on their caretaker. It manifests itself in maladaptive physical and psychological behaviors that are similar to that of panic attacks in humans when the dog is isolated from its owner. These include excessive vocalizations, destructive behaviors, and in more extreme cases, self-mutilation. Currently, there are no direct ways to diagnose separation anxiety without the aid an owner’s report. To ease this diagnostic process, it would be useful to utilize a tool that can distinguish between certain vocalization patterns in dogs. Literature suggests that some …

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Co-Modulation Masking Release Begins In The Auditory Periphery, Kareem R. Hussein, Agudemu Borjigan, Mark Sayles Aug 2017

Co-Modulation Masking Release Begins In The Auditory Periphery, Kareem R. Hussein, Agudemu Borjigan, Mark Sayles

The Summer Undergraduate Research Fellowship (SURF) Symposium

Understanding speech in noisy environments can be difficult, especially for people with hearing loss. The background noise can cover up the sounds of interest. Normally, the auditory system works to alleviate this problem by tagging and then cancelling the noise. Our experiments are aimed at understanding the mechanism of this noise cancellation process. We hypothesize that non-linear signal processing in the mammalian cochlea (the most peripheral part of the auditory system) is the basis of noise cancellation. To test this hypothesis, we measured the responses of auditory-nerve fibers (ANFs) to sounds embedded in background noise with different statistical properties. ANFs …

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Development Of Portable Hyperspectral Imaging Device, Chenxi Li, Youngkee Jung, Iyll-Joon Doh, Euiwon Bae Aug 2017

Development Of Portable Hyperspectral Imaging Device, Chenxi Li, Youngkee Jung, Iyll-Joon Doh, Euiwon Bae

The Summer Undergraduate Research Fellowship (SURF) Symposium

Most of the conventional hyperspectral imaging devices require sophisticated optical components, occupy a large footprint, and requires an initial capital investment for laboratories which mostly suits for laboratories benchtop system. The requirement of shipping the sample and waiting an extended period of time to get the results are the main downsides of this traditional approach. Capitalize in many specific field applications and diagnosis, portable devices provide both convenience and on-site results which are desirable for government agencies and food safety inspectors. This project was aimed to develop a low-cost, portable hyperspectral device for food safety applications. A smartphone was used …

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Development Of A Water Quality Status And Trend Detection Tool*, Ruchir Aggarwal, Valeria Mijares, Margaret W. Gitau Aug 2017

Development Of A Water Quality Status And Trend Detection Tool*, Ruchir Aggarwal, Valeria Mijares, Margaret W. Gitau

The Summer Undergraduate Research Fellowship (SURF) Symposium

Water Quality Index (WQI) models have been developed since the early 1970s. They present a means by which water quality status and trends can be compared across time and space on the basis of a composite value computed using existing water quality data. There is a need for a tool that can bring the different water quality parameters together and calculate the WQIs so as to facilitate data use in predictive modeling and water quality management. We are developing a software tool that can be used by water quality managers and others with different technical backgrounds to calculate WQI of …

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The Effect Of Reinforcing Bar Bend Radius On The Strength And Behavior Of Knee Joints, Xitong Zhou, Christopher S. Williams, Hwa Ching Wang Aug 2017

The Effect Of Reinforcing Bar Bend Radius On The Strength And Behavior Of Knee Joints, Xitong Zhou, Christopher S. Williams, Hwa Ching Wang

The Summer Undergraduate Research Fellowship (SURF) Symposium

The strut-and-tie method (STM) is used by structural engineers to design discontinuity regions of reinforced concrete structures. Using STM, the stress distribution in a concrete member is expressed as a set of struts, ties, and nodes in a strut-and-tie model. These components are then proportioned and evaluated to develop an appropriate design. One type of node that appears in knee joints (i.e., frame corners) subjected to closing moments is referred to as a curved-bar node. Although curved-bar nodes represent a unique concentration of stresses in a structure, little research focused on curved-bar node design has been conducted. In response to …

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Hazard Assessment Of Meteoroid Impact For The Design Of Lunar Habitats, Herta Paola Montoya, Shirley Dyke, Julio A. Ramirez, Antonio Bobet, H. Jay Melosh, Daniel Gomez Aug 2017

Hazard Assessment Of Meteoroid Impact For The Design Of Lunar Habitats, Herta Paola Montoya, Shirley Dyke, Julio A. Ramirez, Antonio Bobet, H. Jay Melosh, Daniel Gomez

The Summer Undergraduate Research Fellowship (SURF) Symposium

The design of self-sustaining lunar habitats is a challenge primarily due to the Moon’s lack of atmospheric protection and hazardous environment. To assure safe habitats that will lead to further lunar and space exploration, it is necessary to assess the different hazards faced on the Moon such as meteoroid impacts, extreme temperatures, and radiation. In particular, meteoroids pose a risk to lunar structures due to their high frequency of occurrence and hypervelocity impact. Continuous meteoroid impacts can harm structural elements and vital equipment compromising the well-being of lunar inhabitants. This study is focused on the hazard conceptualization and quantification of …

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Ocean Wind Speed Measurement Using Wideband Gnss-R Signals, Brandon J. Kozel, Han Zhang, James L. Garrison, Benjamin Nold Aug 2017

Ocean Wind Speed Measurement Using Wideband Gnss-R Signals, Brandon J. Kozel, Han Zhang, James L. Garrison, Benjamin Nold

The Summer Undergraduate Research Fellowship (SURF) Symposium

The use of Global Navigation Satellite System-Reflectometry (GNSS-R) for remote sensing of ocean wind speeds has been explored for nearly two decades and has become an important passive remote sensing technique for verification of hurricane formation models. To obtain wind speed measurements, reflected GNSS signals are first cross-correlated with locally generated copies to construct delay-doppler maps (DDMs). Through statistical models, DDMs can provide information about the mean-square slope (MSS) of the ocean surface, which is related to wind speed. Previous studies have focused on legacy signals such as GPS L1. However, it is expected that the MSS relationship with ocean …

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Intrinsic Regulators Of Actomyosin Contractility Engendering Pulsatile Behaviors, Qilin Yu, Jing Li, Taeyoon Kim Aug 2017

Intrinsic Regulators Of Actomyosin Contractility Engendering Pulsatile Behaviors, Qilin Yu, Jing Li, Taeyoon Kim

The Summer Undergraduate Research Fellowship (SURF) Symposium

Actomyosin contractility regulates various biological processes including cell migration, muscle contraction, and tissue morphogenesis. Cell cortex underlying a membrane, which is a representative actomyosin network in eukaryote cells, exhibits dynamic contractile behaviors. Interestingly, the cell cortex shows reversible aggregation of actin and myosin called pulsatile contraction in diverse cellular phenomena, such as embryogenesis and tissue morphogenesis. While contractile behaviors have been studied in several in vitro experiments and computational studies, none of them demonstrated the pulsatile contraction of actomyosin networks observed in vivo. Here, we used an agent-based computational model based on Brownian dynamics to identify factors facilitating the pulsatile …

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Establishing A Lung Model For Evaluation Of Engineered Lung Microbiome Therapies, Kathryn F. Atherton, Stephen Miloro, Jenna Rickus Aug 2017

Establishing A Lung Model For Evaluation Of Engineered Lung Microbiome Therapies, Kathryn F. Atherton, Stephen Miloro, Jenna Rickus

The Summer Undergraduate Research Fellowship (SURF) Symposium

Benzene, a toxin and carcinogen found in air polluted by cigarette smoke, car exhaust, and industrial processes, is associated with the development of leukemia and lymphoma. Other than avoiding exposure, there is no current method to deter the effects of benzene. One potential strategy to prevent these effects is to engineer the bacteria of the human lung microbiome to degrade benzene. To evaluate this novel approach, we must verify that the bacteria remain viable within the lung microenvironment. To do so, lungs were harvested from rats and swabbed to determine the contents of the original lung microbiome. Then green fluorescent …

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Core-Shell Copper And Nickel Nanofoam: Uniform Electroplating And Properties, Hassan Zbib, David Bahr Aug 2017

Core-Shell Copper And Nickel Nanofoam: Uniform Electroplating And Properties, Hassan Zbib, David Bahr

The Summer Undergraduate Research Fellowship (SURF) Symposium

Characterizing materials on the nanoscale is a key factor to enhance nanotechnology in diverse applications, ranging from electronics to energy fields. However, controlling the structure of the material at the nanoscale or mimicking the nanoscale features of a structure that already exists requires linking processing conditions to the nanostructure. This work focuses on solids that show porous patterns at the nano-micro scale; these are often called cellular solids and classified into two categories: honeycombs and foams. This study focuses on nanofoams; with ligament dimensions in the sub-micron scale. Electrospinning has been developed to produce nanofoam structures of polymers with controlled …

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Modelling Of Phase Transforming Cellular Material (Pxcm), Chidubem N. Enebechi, Yunlan Zhang, David Restrepo Arango, Pablo Zavattieri Aug 2017

Modelling Of Phase Transforming Cellular Material (Pxcm), Chidubem N. Enebechi, Yunlan Zhang, David Restrepo Arango, Pablo Zavattieri

The Summer Undergraduate Research Fellowship (SURF) Symposium

Phase transforming cellular materials (PXCMs) are a new class of materials that can go through large deformation and return to their original configuration. Currently, there are reliable cellular materials that can resist large deformation, for example, honey comb; however, when these materials are compared to PXCMs, they cannot stay in their elastic range. The biggest advantage about PXCMs is that they are not only inexpensive materials, but they are also highly-durable and they absorb and dissipate high amounts of energy. The main concept behind PXCMs is that they contain unit cells that have stable configurations. Each stable configuration of the …

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Purdue Airsense: An Affordable Way To Measure And Study Air Pollution, Stephane Junior Nouafo Wanko, Shadi Tariq Azouz, Ruihang Du, Brandon Boor, Greg Michalski Aug 2017

Purdue Airsense: An Affordable Way To Measure And Study Air Pollution, Stephane Junior Nouafo Wanko, Shadi Tariq Azouz, Ruihang Du, Brandon Boor, Greg Michalski

The Summer Undergraduate Research Fellowship (SURF) Symposium

Air pollution is a major health hazard worldwide, accounting for one-eighth of all deaths in 2012 (World Health Organization). Globally, there is a severe lack of ground-based spatiotemporal monitoring of gaseous and particulate air pollutants, particularly in Africa, South and Central America, and the Middle East. This is in great part due to the high costs of air quality instrumentation that meet accuracy and reliability criteria set by monitoring agencies. The air quality data that is available is often not presented to the public in a user-friendly manner. Taking advantage of recent developments in low-cost sensing technologies, an integrated sensor …

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Numerical Simulations Of Transcritical Natural Convection, Ruiwen Wei, Carlo Scalo, Mario Tindaro Migliorino, Kukjin Kim, Jean-Pierre Hickey Aug 2017

Numerical Simulations Of Transcritical Natural Convection, Ruiwen Wei, Carlo Scalo, Mario Tindaro Migliorino, Kukjin Kim, Jean-Pierre Hickey

The Summer Undergraduate Research Fellowship (SURF) Symposium

In modern engineering applications, system overheating is a key issue that needs to be solved with efficient and reliable cooling technologies. Among the possible mechanisms that these are based on, natural convection cooling is one of the most frequently employed, with applications ranging from cooling of computer micro-components to large nuclear reactors. While many studies have been performed on natural convection employing supercritical or subcritical fluids, little attention has been given to fluids in their transcritical regime. The latter has the potential to yield high performances while avoiding detrimental effects of two-phase systems (e.g. cavitation). In the present study, 2D …

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Surface Tension, Interfacial Tension And Phase Behavior: Interactions Of Surfactant/Polymer Solutions With Crude Oil, Michael A. Steinerd, Jaeyub Chung, Bryan W. Boudouris, Nathan C. Schultheiss, Elias I. Franses Aug 2017

Surface Tension, Interfacial Tension And Phase Behavior: Interactions Of Surfactant/Polymer Solutions With Crude Oil, Michael A. Steinerd, Jaeyub Chung, Bryan W. Boudouris, Nathan C. Schultheiss, Elias I. Franses

The Summer Undergraduate Research Fellowship (SURF) Symposium

Advanced oil recovery techniques, beyond primary and secondary recovery, are required in order to produce additional oil in existing reservoir rock. Here, we evaluated a combination of polymer and surfactant aqueous solutions, in order to generate a working fluid capable of achieving high-performance enhanced oil recovery (EOR). In this recovery process, surfactant is added to the water flooding mixture in order to lower the interfacial tension between the oil and the water. If the interfacial tension can be decreased by ~1,000-fold, then the aqueous solution can mobilize and displace the oil. Moreover, a polymer is added to the aqueous solution …

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Thermodynamics Of Coherent Structures Near Phase Transitions, Julia M. Meyer, Ivan Christov Aug 2017

Thermodynamics Of Coherent Structures Near Phase Transitions, Julia M. Meyer, Ivan Christov

The Summer Undergraduate Research Fellowship (SURF) Symposium

Phase transitions within large-scale systems may be modeled by nonlinear stochastic partial differential equations in which system dynamics are captured by appropriate potentials. Coherent structures in these systems evolve randomly through time; thus, statistical behavior of these fields is of greater interest than particular system realizations. The ability to simulate and predict phase transition behavior has many applications, from material behaviors (e.g., crystallographic phase transformations and coherent movement of granular materials) to traffic congestion. Past research focused on deriving solutions to the system probability density function (PDF), which is the ground-state wave function squared. Until recently, the extent to which …

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A Novel High-Throughput, High-Content Three-Dimensional Assay For Determination Of Tumor Invasion And Dormancy, Mahera M. Husain, Theodore J. Puls, Sherry Voytik-Harbin Aug 2017

A Novel High-Throughput, High-Content Three-Dimensional Assay For Determination Of Tumor Invasion And Dormancy, Mahera M. Husain, Theodore J. Puls, Sherry Voytik-Harbin

The Summer Undergraduate Research Fellowship (SURF) Symposium

Metastasis accounts for most cancer deaths, while dormancy of tumor cells leads to unexpected cancer recurrence. These two aspects of cancer remain relatively untreatable in part because current two-dimensional (2D) methods of high-throughput drug screening cannot quantify outcomes related to these phenotypes. Three-dimensional (3D) in-vitro tumor models are a promising alternative because they better recreate the tumor microenvironment and relevant phenotypes. However, outcome measures for high-throughput screening of these systems are often limited to single measures such as metabolic activity using assays that are not standardized or optimized for 3D models. To address this gap, the objective of this work …

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Analytical Solution Of Microbes Interacting With Surfaces, Junyuan Li, Arezoo M. Ardekani Aug 2017

Analytical Solution Of Microbes Interacting With Surfaces, Junyuan Li, Arezoo M. Ardekani

The Summer Undergraduate Research Fellowship (SURF) Symposium

Nowadays, there is a rising interest in studying the behavior of microbes and their interactions with flow and surfaces. In order to explore the velocity field, pressure and forces around the microbes, the solution of Stokes equations, which is called a Stokeslet, is used. This solution represents a singular velocity field due to a concentrated external force acting on fluid at a single point. This singularity could cause the expression of velocity not integrable. We use the Regularized Stokeslet Method and Method of Images to deal with this problem. The expression of force is replaced by a radially symmetric function, …

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A Parametric Study Of The Mechanics Of Different Skin Flap Techniques, Steven J. Meza, Adrián Tepole Buganza Aug 2017

A Parametric Study Of The Mechanics Of Different Skin Flap Techniques, Steven J. Meza, Adrián Tepole Buganza

The Summer Undergraduate Research Fellowship (SURF) Symposium

In modern day plastic and reconstructive surgeries numerous skin flap designs have been developed and are used to close open wounds. Skin flaps are developed with the intention of imposing minimal tension in skin closure. Excessive tension can lead to poor blood flow that result in post-surgery complications such as necrosis. Currently there is no standard in choosing a skin flap design and a surgeon's choice is based personal experience. A comparison of the mechanical loading in these various designs has not yet been done. We have developed a parametric study, using finite element analysis, of two advancement skin flaps …

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