Engineering Commons^™

Tunneling Nanotubes: An Alternate Route For Propagation Of The Bystander Effect Following Oncolytic Viral Infection, Justin Ady, Venugopal Thayanithy, Kelly Mojica, Phillip Wong, Joshua Carson, Prassanna Rao, Yuman Fong, Emil Lou

Biomedical Engineering and Sciences Faculty Publications

Tunneling nanotubes (TNTs) are ultrafine, filamentous actin-based cytoplasmic extensions which form spontaneously to connect cells at short and long-range distances. We have previously described long-range intercellular communication via TNTs connecting mesothelioma cells in vitro and demonstrated TNTs in intact tumors from patients with mesothelioma. Here, we investigate the ability of TNTs to mediate a viral thymidine kinase based bystander effect after oncolytic viral infection and administration of the nucleoside analog ganciclovir. Using confocal microscopy we assessed the ability of TNTs to propagate enhanced green fluorescent protein (eGFP), which is encoded by the herpes simplex virus NV1066, from infected to uninfected …

Isopropyl Alcohol Pump For Printed Circuit Boards Using An Arduino, Lawrence Zhu

Computer Engineering

No abstract provided.

Investigation Of The Optical Properties Of Pbse/Pbx Nanocrystals For Photodetector Applications, Haley Ann Morris

Graduate Theses and Dissertations

Lead selenide and lead selenide/lead sulfide core/shell nanocrystals were investigated for use in near infrared photodetectors. A colloidal synthesis method was used for both the core and core/shell configurations. The lead sulfide shell was examined in order to mitigate oxidation of the nanoparticle surface. Absorbance and photoluminescence spectra were measured at room temperature and 77 K, respectively. Transmission electron microscopy images were also obtained to confirm crystallography and size. Bulk lead selenide was simulated in WIEN2k utilizing the linear-augmented plane wave method of solving density functional theory to better understand the electronic structure of PbSe. The crystal structure, electron density, …

Hollow Fiber Membranes For Artificial Lung Applications, Lauren Reed

Chemical Engineering Undergraduate Honors Theses

Artificial lungs are in use, but difficult issues remain in the field of membrane development related to fouling issues. Currently there are external artificial lungs circulating blood outside the body, taking out the carbon dioxide, and inserting oxygenated blood back into the body. An example of this type of machine is the ExtraCorporeal Membrane Oxygenation (ECMO) machine currently used in hospitals. The ECMO takes over the functions for both the lungs and the heart but is only available for short term use by patients with respiratory failure due to infections [1]. The fibers in the machine develop fouling due to …

Overseas Chinese Environmental Engineers And Scientists Association (Oceesa) Report, Dec 2016., Yung-Tse Hung, Wen-Chi Ku, Lawrence K. Wang

Civil and Environmental Engineering Faculty Publications

This Overseas Chinese Environmental Engineers and Scientists Association (OCEESA) report is 2016 Directory of Overseas Chinese Environmental Engineers and Scientists Association (OCEESA), Report number: OCEESA/JL-2016/33D1, December 2016, ISSN 1072 -7248. This report was prepared by Yung-Tse Hung, Permanent Executive Director, OCEESA. This report includes OCEESA contact information, list of OCEESA Directors, list of OCEESA past presidents, OCEESA membership data, constitutions and by laws of OCEESA (5 November 2000 edition), constitutions and by laws of OCEESA (14 February 2006 edition), constitutions and by laws of OCEESA (27 October 2013 edition), membership application form, letter from Wen-Chi Ku to confirm Yung-Tse Hung …

Indoor Scene Localization To Fight Sex Trafficking In Hotels, Abigail Stylianou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Images are key to fighting sex trafficking. They are: (a) used to advertise for sex services,(b) shared among criminal networks, and (c) connect a person in an image to the place where the image was taken. This work explores the ability to link images to indoor places in order to support the investigation and prosecution of sex trafficking. We propose and develop a framework that includes a database of open-source information available on the Internet, a crowd-sourcing approach to gathering additional images, and explore a variety of matching approaches based both on hand-tuned features such as SIFT and learned features …

Examination Of Pseudomonas Fluorescence As A Recombinant Expression Host: Cloning, Expression, And Chromatography, Ahmed K.Ali Elmasheiti

Graduate Theses and Dissertations

In an effort to expand the pool of bacterium useful for biotechnology applications, Pseudomonas fluorescens, a common gram negative microbe, was examined for its ability to function in a recombinant setting. P. fluorescens is ubiquitous in nature and was initially identified as a soil bacterium found in dirt and is typically associated with plant material. Past literature indicates that it shared characteristics common to Escherichia coli and Bacillus subtilis, including simple growth conditions and potential cloning vectors, providing motivation to look into both the upstream and downstream characteristics of this bacterium. First, it was demonstrated that P. fluorescens could be …

Continuous Long-Term Health Monitoring Using Ultrasonic Wave Propagation, Ece Erdogmus

Nebraska Department of Transportation: Research Reports

No abstract provided.

Multipath And Rate Stability, Junjie Liu, Roch A. Guérin

All Computer Science and Engineering Research

Originally Published In Proc. IEEE Globecom Conference - CQRM: Communication QoS, Reliability & Modeling Symposium

Exploring The Production Of Extracellular Matrix By Astrocytes In Response To Mimetic Traumatic Brain Injury, Addison Walker

Graduate Theses and Dissertations

Following injury to the central nervous system, extracellular modulations are apparent at

the site of injury, often resulting in a glial scar. Astrocytes are mechanosensitive cells, which can create a neuroinhibitory extracellular environment in response to injury. The aim for this research was to gain a fundamental understanding of the affects a diffuse traumatic brain injury has on the astrocyte extracellular environment after injury. To accomplish this, a bioreactor culturing astrocytes in 3D constructs delivered 150G decelerations with 20% biaxial strain to mimic a traumatic brain injury. Experiments were designed to compare the potential effects of media type, number of …

Si-Based Germanium-Tin (Gesn) Emitters For Short-Wave Infrared Optoelectronics, Seyed Amir Ghetmiri

Graduate Theses and Dissertations

Conventional integrated electronics have reached a physical limit, and their efficiency has been influenced by the generated heat in the high-density electronic packages. Integrated photonic circuits based on the highly developed Si complementary-metal-oxide-semiconductor (CMOS) infrastructure was proposed as a viable solution; however, Si-based emitters are the most challenging component for the monolithic integrated photonic circuits. The indirect bandgap of silicon and germanium is a bottleneck for the further development of photonic and optoelectronic integrated circuits.

The Ge1-xSnx alloy, a group IV material system compatible with Si CMOS technology, was suggested as a desirable material that theoretically exhibits a direct bandgap …

A Genetic Algorithm Incorporating Design Choice For The Preliminary Design Of Unmanned Aerial Vehicles, Kenneth Michael Mull

Masters Theses

Unmanned Aerial Vehicles (UAVs) are currently at the forefront of aerospace technologies. The design of these aircraft is complex and often performance characteristics are coupled to multiple design attributes. At the early design phase both discrete and continuous design choices are present limiting the feasibility of traditional derivative based optimization techniques. In place of these methods, the design space can be explored using a genetic algorithm that mimics the process of natural selection, providing a capable and reliable base airframe constructed from the required performance metrics. By incorporating a genetic multidisciplinary optimization algorithm early in the conceptual design phase, aircraft …

Improved Methodology For Developing Non-Motorized Safety Perfomance Functions, Keneth Morgan Kwayu

Masters Theses

This study aimed at improving the methodology for developing statewide non-motorized safety performance functions (SPFs). Due to lack of pedestrian and bicyclist counts, the methodology proposed a procedure for developing statewide surrogate non-motorized exposure measures using data that are available at statewide level. Eleven years non-motorized crashes at signalized urban intersections joining Arterial and Collector roads in Michigan were used to test the procedure.

The study also explored the use of Bayesian approach for modeling non-motorized crashes as an alternative to traditional classical count data models. Classical count data models that were considered as potential fit to the data include; …

Modeling, Optimizing And Testing Thermoelectric Generators For Liquid-To-Liquid Low Grade Waste Heat Recovery, Ali Eyddan Hamil

Masters Theses

The use of thermoelectric generators (TEGs) for producing electricity from low grade waste heat is thought to be a great solution in the future to reduce the power generation cost because of their advantages of reliability and environmental friendliness. Therefore, the current project aims to study thermoelectric generators for low grade waste heat recovery. In this work, a single unit cell of liquid to liquid thermoelectric generator attached with heat exchangers (heat sinks) is modeled using an internal flow. Its optimum design is obtained based on heat sink optimization and the optimal design method. An analytical model of four unit …

Analytical Study Of Miniature Thermoelectric Device, Mohammed Dhannoon

Masters Theses

Miniature thermoelectric devices (TE) have been regarded as hopeful devices to attain efficient cooling in microprocessors and other small-scale devices. To recognize the performances of miniature thermoelectric coolers, a thermoelectric cooling module is theoretically analyzed. Particular attention is paid to the impact of the thermoelectric element length effect and the substrate material type influence on the cooling performance. The electrical contact resistance and thermal contact are taken into account.

Furthermore, miniature thermoelectric is compared with large thermoelectric, and effective material properties of miniature thermoelectric are studied. The obtained results also demonstrate power density (cooling/heating power per unit area of the …

Effects Of The Cooling Rate On The Shear Behavior Of Continuous Glass Fiber/Impact Polypropylene Composites (Gf-Ipp), H. Wafai, G. Lubineau, A. Yudhanto, M. Mulle, W. Schijve, N. Verghese

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Fiber-reinforced composites with improved dissipation of energy during impact loading have recently been developed based on a polypropylene copolymer commonly called impact polypropylene (IPP). Composites made of IPP reinforced with glass fibers (GF) are particularly attractive to the automotive industry due to their low cost and good impact resistance. In such composites, the cooling rate varies depending on processing techniques and manufacturing choices. Here, we study the effects of the cooling rate of GF-IPP composites on shear behavior, which is critical in impact applications, using [±45]s monotonic and cyclic (load/unload) tensile specimens. The specimens were manufactured under a wide range …

Feature Based Object Tracking: A Probabilistic Approach, Kaleb Smith

Theses and Dissertations

Video analysis is a rich research topic, due to the wide spectrum of applications such as surveillance, activity recognition, security, and event detection. One of the important challenges in video analysis is object tracking, which provides the ability to determine the exact location of an object of interest within each frame. Many challenges affect the efficiency of a tracking algorithm such as scene illumination change, occlusion, scaling change and determining a search window from which to track object(s). We present an integrated probabilistic model for object track- ing, that combines implicit dynamic shape representations and probabilistic object modeling. We demonstrate …

A Robotic Device To Assist With In-Vivo Measurement Of Human Pelvic Organ Tissue Properties, Shashank S. Kumat

Mechanical and Aerospace Engineering Theses - Archive

Measurement of the biomechanical properties of human pelvic organ tissue without undergoing minimally invasive surgery is desired for diagnostics purposes and take precautionary actions if needed. The biomechanical properties of the bladder change with age and due to diseases. Thus, identification of the viscoelastic properties of the tissue could help in detecting early stages of the disease in the bladder. A literature survey revealed that no device exists that could be used to characterize the biomechanical properties of the human bladder in-vivo. This research contributes towards the development of a diagnostic system that could be used in a medical setting …

The Influence Of Functional Weights On The Performance Of Least Squares Finite Element Formulation On Hybrid Meshes, Anirudh Rajagopal

Mechanical and Aerospace Engineering Theses - Archive

The Least-Squares Finite Element Method (LSFEM) is a numerical method for solving partial differential equations (PDE) approximately by minimizing the L-2 norm of the PDE residuals. Unlike the more common Galerkin approach, this method does not employ integration by parts to reduce the continuity requirements of the basis functions. Instead, the PDE is cast as a first-order system of differential equations, which allows for the solution of primary and secondary variables with the same order of accuracy. In addition, this approach always leads to a direct minimization problem and therefore not subject to the restrictive inf-sup condition and does not …

Application Of Artificial Neural Network For Evaporative Cooling In Data Centres, Feyisola Adejokun

Mechanical and Aerospace Engineering Theses - Archive

A data center is a facility that may be used to house telecommunication or storage devices. Because of the 24/7 required operation of a data center, large segments of a data center are geared towards evacuating heat generated from operating one. Data centers entail multiple operating configurations, great amount of constraints and nonlinear correlations. The need to effectively optimize a data center operation presents a daunting challenge. The data center considered in this research is a test bed modular data center (MDC). Comprising of an Information Technology (IT), DEC and IEC module. Typical MDC are dynamic and complex in nature …

Shape Optimization Of Helical Coil Tube For Maximizing Heat Transfer, Venkat Manoj Kandukuri

Mechanical and Aerospace Engineering Theses - Archive

Many researchers have observed the enhancement of heat transfer in coiled tubes compared to straight tubes with the same diameter and length. It is known fact, that in a helical coil tube the maximum axial velocity shifted towards the outer wall of the pipe and imbalance between centrifugal forces and inertial loads to a secondary motion of the fluid in the cross-section of the tube. This secondary motion is responsible for improved transport of heat energy to/from the tube walls. Previous conducted Experimental and computational parametric studies show the relationship between the increased heat transfer and parameters such as pitch, …

Self-Transport Of Liquid Drops Through A Functional Mesh For Removing Sweat Away From Skin, Manasvikumar Oza

Mechanical and Aerospace Engineering Theses - Archive

In this work, a functional mesh is developed to transport liquid drops from one side of the mesh to the other. A theoretical model is established, which has been used to obtain three design criteria. Based on these design criteria, functional meshes have been generated and tested with commercially available sponge attached to the mesh. Finally, such a mesh is demonstrated to be effective to remove sweat from human skin. As an application of this research, the concept of this functional mesh solves existing problems with a sport wear. The current sport wear is capable of absorbing sweat, but not …

Thermal Stress Analysis Of Unidirectional Composite Material By Fem Modeling, Gopal D. Gulwani

Mechanical and Aerospace Engineering Theses - Archive

Micromechanics of composite is study of complex mechanism of stress and strain transfer between fiber and matrix within a composite as well as distributions of physical fields inside heterogeneous medium. It was used successfully in predicting accurately physical properties like effective stiffness, effective linear thermal expansion of heterogeneous materials like composite. However, when it comes to strength characteristics of composite especially in transversal direction it failed to predict more accurate results. This thesis is focused on thermally induced stress analysis of unidirectional composite by finite element method. Thermal stresses which are dangerously ignored factor in mechanics of composite usually occur …

A Novel Supercell-Based Dielectric Grating Dual-Beam Leaky-Wave Antenna For 60-Ghz Applications, Zi Long Ma, Kung Bo Ng, Chi Hou Chan, Li (Lijun) Jun Jiang

Electrical and Computer Engineering Faculty Research & Creative Works

This communication proposes a novel dual-beam dielectric grating antenna based on the supercell (SC) concept. Through the theoretical analysis of the effective phase constants of the SC, it is found that two space harmonic modes (m=-1 and m=-2) can be simultaneously excited (above the air line) within a certain frequency range. This phenomenon leads to the generation of two radiation beams in the far-field region. At the frequency where the phase constants satisfy β-1=-β-2, the two beams are in symmetric directions with respect to the axis that is perpendicular to the azimuth plane. Different from the conventional periodic structures that …

The Prescribed Burning Impacts On Soil Water Repellency And Soil Hydrological Properties In Sagebrush-Steppe Ecosystem, Yang Cheng

Dissertations - ALL

Prescribed fire is an important tool for rangeland management in sage-steppe ecosystem, yet the long-term effects of this practice have not been well studied. Previous studies of fire-affected soil water repellency have identified the strength and persistence of SWR after burning in different types of forests but have not identified consistent timelines for post-fire recovery. This study explores the impacts of fire and plant community succession on SWR and infiltration properties to further inform rangeland managers regarding the long-term impacts of prescribed fire on SWR and infiltration properties in sagebrush-steppe ecosystems.

The objectives of this study were: 1) To explore …

Statistical Mechanical Treatments Of The Optical Properties Of Cadmium Selenide Quantum Dots, Amogh Srihari

Dissertations - ALL

Semiconductors that exist in the nanoscale are referred to as Quantum Dots (QDs). This distinction is made because in the nanoscale, semiconductors behave much differently compared to their bulk counterparts. QDs possess band gaps that change based on their size and this unique property enables them to emit different colors, rendering them useful in a number of applications. QDs are widely used in LED technology and are becoming commonplace in biological applications involving in-vivo imaging. Efforts have gone into making QDs viable for photovoltaic applications as well. Although a lot is understood about the effects of size and shape on …

Kinetics Of Ketone Hydrogenation Over Supported Ru Catalysts, Omar Abdelrahman Ali Abdelrahman

Dissertations - ALL

A kinetic investigation of the production of y-valerolactone (GVL) via the aqueous phase hydrogenation of levulinic acid (LA) over supported Ru catalysts was carried out, in order to understand how to better design a hydrogenation catalyst for such biomass catalytic strategies. At temperatures representative of biomass processing, the reaction proceeds first through the reduction of the LA ketone group to its corresponding alcohol, 4-hydroxypentanoic acid (HPA), which subsequently produces GVL via intramolecular esterification in solution. The governing kinetics of LA hydrogenation were found to be insensitive to the identity of the support material on which Ru catalysts were prepared. Conversely …

Sensor Management For Localization And Tracking In Wireless Sensor Networks, Nianxia Cao

Dissertations - ALL

Wireless sensor networks (WSNs) are very useful in many application areas including battlefield surveillance, environment monitoring and target tracking, industrial processes and health monitoring and control. The classical WSNs are composed of large number of densely deployed sensors, where sensors are battery-powered devices with limited signal processing capabilities. In the crowdsourcing based WSNs, users who carry devices with built-in sensors are recruited as sensors. In both WSNs, the sensors send their observations regarding the target to a central node called the fusion center for final inference. With limited resources, such as limited communication bandwidth among the WSNs and limited sensor …

Neuromorphic Learning Systems For Supervised And Unsupervised Applications, Qiuwen Chen

Dissertations - ALL

The advancements in high performance computing (HPC) have enabled the large-scale implementation of neuromorphic learning models and pushed the research on computational intelligence into a new era. Those bio-inspired models are constructed on top of unified building blocks, i.e. neurons, and have revealed potentials for learning of complex information. Two major challenges remain in neuromorphic computing. Firstly, sophisticated structuring methods are needed to determine the connectivity of the neurons in order to model various problems accurately. Secondly, the models need to adapt to non-traditional architectures for improved computation speed and energy efficiency. In this thesis, we address these two problems …

Selective Dynamic Analysis Of Virtualized Whole-System Guest Environments, Andrew William Henderson

Dissertations - ALL

Dynamic binary analysis is a prevalent and indispensable technique in program analysis. While several dynamic binary analysis tools and frameworks have been proposed, all suffer from one or more of: prohibitive performance degradation, a semantic gap between the analysis code and the execution under analysis, architecture/OS specificity, being user-mode only, and lacking flexibility and extendability. This dissertation describes the design of the Dynamic Executable Code Analysis Framework (DECAF), a virtual machine-based, multi-target, whole-system dynamic binary analysis framework. In short, DECAF seeks to address the shortcomings of existing whole-system dynamic analysis tools and extend the state of the art by utilizing …