Polyamine Modulation In Alcoholism: Examination Using A Novel Screening Procedure Designed To Predict Anti-Relapse And Neuroprotective Efficacy,
2011
University of Kentucky
Polyamine Modulation In Alcoholism: Examination Using A Novel Screening Procedure Designed To Predict Anti-Relapse And Neuroprotective Efficacy, J. Ben Lewis
University of Kentucky Doctoral Dissertations
Alcohol dependence is a major public health concern. Despite the FDA’s approval of multiple anti-relapse drugs, relapse rates remain unacceptably high. Furthermore, cognitive deficits among chronic drinkers are evident and are suggested to contribute to relapse risk. Current evidence suggests that several critical features of alcoholism and alcohol-associated neurodegeneration are mechanistically linked to glutamatergic actions; specifically, they appear positively affected by glutamatergic inhibition, particularly inhibition via polyamine modulation of a subpopulation of n-methyl-d-aspartate receptors. The current project was designed to evaluate the performance of two putative polyamine modulators (JR-220 and CP-101,606) in a variety of screens designed …
Effectiveness Of A Motivational Enhancement Group Treatment In A Community Treatment Program With A Substance Abusing Population,
2011
Western Michigan University
Effectiveness Of A Motivational Enhancement Group Treatment In A Community Treatment Program With A Substance Abusing Population, Matthew S. Willerick
Dissertations
Motivational interviewing (MI) is a directive, client-centered intervention to elicit behavior change by assisting clients in the exploration and resolution of ambivalence toward change. MI-inspired approaches have been used in an attempt to facilitate change in a wide variety of domains including alcohol and drug abuse, safe water handling practices, dual diagnoses, gambling, spousal abuse, health related areas, mood and anxiety disorders, and parental engagement. MI seeks to resolve ambivalence in the direction of change by increasing the client's self-efficacy. This is accomplished by combining clientcentered (e.g., reflective listening) and directive strategies (e.g., attending selectively to change statements). The origins …
Is There A Genetic Basis For Alcoholism?,
2011
Touro College
Is There A Genetic Basis For Alcoholism?, David Aharonoff
The Science Journal of the Lander College of Arts and Sciences
This paper reviews studies done on the correlation of alcoholism and genetics. Evidence of this correlation can be seen in high heritability of alcoholism. The main methods used in determining genetic risk factors are candidate gene studies and genome wide studies. This review focuses mainly on findings related to specific neurotransmitters and receptors in relation to alcoholism. Evidence has shown that specific neurotransmitters and receptors can play a role in increased susceptibility to alcoholism. The neurotransmitters and receptors discussed in this paper include GABA, glutamate, and endogenous opioids. There is also a discussion focused on mutations of specific enzymes (ADH …
Exploring The Well-Being Of Foster Children Of Parents With Substance Abuse Problems In Family Dependency Treatment Courts,
2011
Western Michigan University
Exploring The Well-Being Of Foster Children Of Parents With Substance Abuse Problems In Family Dependency Treatment Courts, Barbara M. Howes
Dissertations
The aim of this three-paper format dissertation is to explore how the well-being of foster children of parents with substance abuse problems is defined and promoted through Family Dependency Treatment Courts (FDTC) within the context of the Adoption and Safe Families Act (ASFA). The benefit to the author of the three-paper method is the task of submitting the findings of the study for publication is eased as the dissertation contains three stand-alone articles. A drawback for the reader of the three paper method is that there is redundancy in reading the same sections in each paper. The reader is encouraged …
Focus On Male Youths In Addressing Alcohol And Drug Abuse Risk In The Context Of Hiv Prevention Among Young People,
2011
Population Council
Focus On Male Youths In Addressing Alcohol And Drug Abuse Risk In The Context Of Hiv Prevention Among Young People, Population Council
Reproductive Health
Research evidence shows that people who abuse alcohol are more likely to engage in behavior that puts them at risk of HIV infection, including having unprotected sex. In 2010, the Population Council’s APHIA II Operations Research Project collaborated with the Support for Addictions Prevention and Treatment in Africa Centre in Kenya on research to identify factors associated with alcohol and drug use among out-of-school youth in Kibera, to identify specific factors contributing to HIV risk, and to assess the impact of an intervention to link youths with an alcohol and drug abuse problem to counseling and rehabilitation services. A key …
Maternal Effects On Ethanol Teratogenesis In A Cross Between A/J And C57bl/6j Mice,
2011
University of Northern Colorado
Maternal Effects On Ethanol Teratogenesis In A Cross Between A/J And C57bl/6j Mice, David Gilliam, Nate Valdez, Scott Branson, Ashley Dixon, Chris Downing
School of Psychological Sciences Faculty Publications
Genetic factors influence adverse pregnancy outcome in both humans and animal models. Animal research reveals both the maternal and fetal genetic profiles are important for determining the risk of physical birth defects and prenatal mortality. Using a reciprocal-cross breeding design, we investigated whether the mother’s genes may be more important than fetal genes in determining risk for ethanol teratogenesis. Examination of possible synergistic genetic effects on ethanol teratogenesis was made possible by using two mouse strains known to be susceptible to specific malformations. Inbred A/J (A) and C57BL/6J (B6) mice were mated to produce four fetal genotype groups: the true-bred …
Integrating Alcohol Risk Reduction Into Htc Services,
2011
Population Council
Integrating Alcohol Risk Reduction Into Htc Services, Population Council
Reproductive Health
This brief describes how screening for alcohol abuse and hosting long-term support groups through HIV testing and counseling centers (HTC) is one way to decrease high-risk sexual and alcohol behaviors among people who have tested for HIV. Findings from program activities funded by Population Council, Liverpool VCT and Support for Addiction Prevention and Treatment in Africa Center (SAPTA) found that screening HTC clients for alcohol abuse and referral to active support and counseling services is feasible. Follow up using SMS is also recommended. However, the lack of a control group in this study may hinder drawing direct causality between the …
The Effects Of Childhood Sexual Abuse On Women In Recovery For Substance Abuse,
2011
California State University, San Bernardino
The Effects Of Childhood Sexual Abuse On Women In Recovery For Substance Abuse, Barbara Eileen Egan
Theses Digitization Project
This study assessed if women who are survivors of Childhood Sexual Abuse and receive treatment for this issue, when they were in treatment for substance abuse, stayed sober longer and thus experienced a healthier and happier recovery. The benefit of this research is two-fold as it not only leads to better treatment programs for women who have this co-occurring condition, it also allows for better treatment outcomes and as a result is more cost effective for treatment agencies. The data was collected confidentially through surveys that were distributed at 10 local Alcoholic's Anonymous meetings in the Inland Empire area.
Substance Abuse Services And Their Effects On Parental Reunification With Children Within The Child Welfare System,
2011
California State University, San Bernardino
Substance Abuse Services And Their Effects On Parental Reunification With Children Within The Child Welfare System, Jacqueline Ann Myers
Theses Digitization Project
This study explained the affect of the parental substance abuse services on the reuniting of the parents with their children. Understanding the significance of parental substance abuse treatment services in regards to reunification with children within the child welfare system is necessary in providing children with a healthy and safe environment.
Gratitude Intervention And Its Effect On Substance Abusers,
2011
California State University, San Bernardino
Gratitude Intervention And Its Effect On Substance Abusers, Patricia Kelleen Mcclanahan
Theses Digitization Project
The purpose of this study is to investigate the effects of an intervention seen to increase life satisfaction in substance abuse treatment. While treatment models have improved, results remain low for long-term abstinence. The study participants were substance-abuse treatment clients at Mental Health Systems (MHS). This study will measure, in terms of increased life satisfaction, the effectiveness of a daily gratitude list on the negative mindset of substance abusers in treatment. The focus of this study will be the use of intervention that has been seen as beneficial in enhancing personal well-being.
The Stigmatization Of Methadone Maintenance Treatment And Its Effect On Social Support,
2011
California State University, San Bernardino
The Stigmatization Of Methadone Maintenance Treatment And Its Effect On Social Support, Kenia Gabriela Rivas, Franceen Mary Rosales
Theses Digitization Project
The purpose of this study was to explore the correlation between perceived stigmatization from family as well as friends and its probable effects on social support from the same. Methadone Maintenance Treatment (MMT) is a treatment modality that has been proven to help achieve abstinence. However, due to controversy over MMT, this has brought stigmatization, social injustice and powerlessness to those who seek out treatment.
Social Workers' Perceptions Regarding "At Risk" And Delinquent Foster Care Youth,
2011
California State University, San Bernardino
Social Workers' Perceptions Regarding "At Risk" And Delinquent Foster Care Youth, Laura June Deluca, Mallory Michelle Flores
Theses Digitization Project
This thesis explores the experiences of social workers within San Bernardino County's Children and Family Services who are working with delinquent and high-risk youth within foster care. Social workers were asked to describe services that are available and the potential protective risk factors that may exist. It is imperative to understand this population and the services that exist in order to address this problem and better meet the needs of youth.
2011 Annual Report,
2011
Nova Southeastern University
2011 Annual Report, Center For Applied Research On Substance Use And Health Disparities
Center for Applied Research on Substance Use and Health Disparities Annual Reports
No abstract provided.
How Do We ‘See’ Occupations? An Examination Of Visual Research Methodologies In The Study Of Human Occupation,
2010
The University of Western Ontario
How Do We ‘See’ Occupations? An Examination Of Visual Research Methodologies In The Study Of Human Occupation, L. Hartman, A. Mandich, L. Magalhaes, Treena Orchard
Dr. Treena Orchard
This article argues that visual research methodologies have potential to contribute to the study of occupation. The use of visual research methodologies is quickly growing in a number of disciplines and can help researchers to access information and reasoning not accessible through interview, log or survey. The reflexive, reflective, engaged process of creating and analysing visual materials allows for rich representations on behalf of participants, and immersion in the data on the part of researchers. This paper explores photovoice, body mapping and textual analysis of visual materials to understand how they can contribute to occupational science research. These methods were …
'What's The Use Of Getting A Cow If You Can't Make Any Money From It?': The Reproduction Of Inequality Within Contemporary Social Reforms Of Devadasis,
2010
The University of Western Ontario
'What's The Use Of Getting A Cow If You Can't Make Any Money From It?': The Reproduction Of Inequality Within Contemporary Social Reforms Of Devadasis, Treena Orchard
Dr. Treena Orchard
No abstract provided.
The Role Of Problem Orientation Cognitive Distortions In Depression And Anxiety Intervention For Young Adults.,
2010
University of Wollongong
The Role Of Problem Orientation Cognitive Distortions In Depression And Anxiety Intervention For Young Adults., Coralie Wilson
Coralie J Wilson
Interventions that aim to improve social problem-solving skills can significantly reduce the severity of anxiety and depression symptoms in young people. Anxious and depressed individuals often have a negative orientation to problem solution which acts as a barrier to implementing problem-solving skills. Research with older adults suggests that symptoms impair problem-solving abilities through cognitive processes associated with the development of anxiety and depression. In this study we extend previous investigations by assessing the extent to which specific cognitive distortions and symptoms of anxiety and depression are associated with negative problem orientation in a sample of 285 young adults aged 18 …
Rural Adolescents’ Help Seeking Intentions For Emotional Problems: The Influence Of Perceived Benefits And Stoicism.,
2010
University of Wollongong
Rural Adolescents’ Help Seeking Intentions For Emotional Problems: The Influence Of Perceived Benefits And Stoicism., Coralie Wilson
Coralie J Wilson
This paper is the second from a larger multi-cite study developed and led by the third author which explores factors that influence adolescents' help-seeking intentions. Specifically, this paper investigates the extent to which perceived benefits of help seeking, stoicism, gender and symptoms of psychological distress are associated with intentions to seek professional help for emotional problems. A cross sectional self-report questionnaire was administered to adolescents recruited from seven high schools in rural towns in the Riverina region of New South Wales. A total of 778 adolescents were recruited. The sample included 373 male and 404 female participants between 13 and …
Moral Undertow And The Passions: Two Challenges For Contemporary Emotion Regulation,
2010
The University of Western Ontario
Moral Undertow And The Passions: Two Challenges For Contemporary Emotion Regulation, Louis Charland
Louis C. Charland
No abstract provided.
Decision-Making Capacity And Responsibility In Addiction,
2010
The University of Western Ontario
Decision-Making Capacity And Responsibility In Addiction, Louis Charland
Louis C. Charland
No abstract provided.
Predicting Adolescents’ Future Intentions To Seek Help For Mental Health Problems.,
2010
University of Wollongong
Predicting Adolescents’ Future Intentions To Seek Help For Mental Health Problems., Coralie J. Wilson
Frank Deane
This study examined whether high school students’ current symptoms of general psychological distress, self-rated social problem-solving skills, and recent help-seeking experiences predict their future intentions to seek help for a mental health problem. At Time 1, 98 high school students, aged 12-17 years, completed the study self-report survey that included measures of psychological distress, social problem-solving skill, and recent help-seeking behaviour. At Time 2, three weeks later, the same students completed measures of help-seeking intentions. Students with more severe levels of distress symptoms at Time 1 had lower intentions to seek help for a mental health problem at Time 2. …
