Biology Commons^™

Development Of Mouse Melanoma Model To Evaluate Oncolytic Viral Therapy Using Osv, Kelli A. Clemons

Honors Theses

No abstract provided.

Seed Germination Requirements For Four Fire-Recruiter Chaparral Shrubs, Kati Mcclain

Senior Honors Projects

Wildfires are a natural part of chaparral ecosystems, as they are essential to vegetative regrowth and plant recruitment. For many chaparral species, fire stimulates germination of dormant seeds in the seed bank. This study explored fire-related cues necessary for seed to break dormancy, germinate, and emerge in four chaparral species (Ceanothus cuneatus, C. jepsonii, Arctostaphylos manzanita, A. viscida). Seed were exposed to various treatments mimicking wildfire conditions, including boiling water and charred wood (charate), as well as physical scarification by concentrated acid, and monitored for germination. Our data indicate that Ceanothus seed require heat cues to germinate, but fire-related chemical …

An Analysis Of The Allelopathic Relationship Between Basil (Ocimum Basilicum) And Tomatoes (Solanum Lycopersicum) As An Alternative To Fertilizer, Keondra Jenkins

Student Writing

Allelopathy is a trait within certain organisms that allows them to produce and secrete certain biochemical that have various effects on other organism’s growth, survival, and reproduction processes. This study compared the growth results of the allelopathic relationship between basil and tomatoes against fertilized tomatoes and untreated tomatoes. With the information from this study and conclusions can be made about whether or not allelopathic or “companion planting” can serve as a viable alternative for fertilizer.

After nearly 5 months of growth, the allelopathic properties of basil were found to be equal, if not more, beneficial to the growth of the …

Volume 08, Meghan Enzinna, Casey Dawn Gailey, Raven Collins, Chiara Enriquez, Amelia Mcconnell, Alexander Morton, Emma Beckett, Leah G. Parr, Briana Adhikusuma, Taylor Embrey, Rowan Davis, Danielle Sisson, Bianca Cherry, Melissa Cacho, Chloe Woodward, Catherine Rollins, Carson Reeher, Landon Cooper, Haley Vasquez, Marlisha Stewart, Eric Whitehead, Sabrina Walker, James Bates

Incite: The Journal of Undergraduate Scholarship

Introduction from Interim Dean Dr. Jennifer Apperson

Indigenous Peoples and the Modern Era by Meghan Enzinna

"Who Says": How Selena Gomez and the Scene Attempt to Subvert the Popular Standards of Beauty by Casey Dawn Gailey

Art by Raven Collins

Meltdown on Social Media: Amy's Baking Company Meets Kitchen Nightmares by Nathena Haddrill

Art by Chiara Enriquez

Design by Amelia Mcconnell

Worth More Than a Thousand Words: A Visual Rhetorical Discussion of Virtual Reality by Examining "Clouds Over Sidra" by Alexander Morton

Design by Emma Beckett

The Sonata: An Analysis of Piano Sonata No. 14 in C Minor, K. …

Brain Tumor In A Dish: Glioma/Astrocyte Co-Cultures As A Model For In Vitro Studies, Erin Eickman, Christina Wilson, Srivatsan Kidambi

UCARE Research Products

This study seeks to engineer an in vitro co-culture model to elucidate the role of glioma-astrocyte interactions on molecular changes in the tumor microenvironment. The use of patterned co-cultures created with polyelectrolyte multilayers and micromolding in capillaries will allow tthe investigation of cell-cell communication. This study will lead to better understanding of the role of healthy cells in cancer progression and potential treatment options.

Computational Modeling Intervention: Using Dynamical Models To Teach Complex Biological Processes, Audrey J. Crowther, Tomáš Helikar, Nicholas Galt, Joseph Dauer, Heather Berganr, Bryan Kowal

UCARE Research Products

The Unites States, while being one of the richest countries in the world, ranks 17th in science proficiency out of 31 countries. New techniques for teaching are needed if the US wants to keep up with increasing global competition. Often the problem with traditional methods for teaching biological processes is that they present the material as linear or causal, when in fact there is a much wider network at play. For example, cellular respiration is often represented as a linear process that always starts with glucose and always ends with ATP and water. However, there are several entry and exit …

What Are The Genes That Cause Male Sterility In Hybrid Offspring Between Drosophila Mauritiana And Drosophila Simulans?, Naznaz J. Majid, Colin D. Meiklejohn

UCARE Research Products

The purpose of this research project is to better understand speciation -- the process by which new species arise. To better understand how species form we will investigate how reproductive barriers come about-specifically the sterility of hybrid offspring will be the focus of this research. The species under investigation are Drosophila mauritiana and D. simulans that produce sterile hybrid males. These species are used specifically because they produce fertile hybrid females which allow genes to be moved between them. There are also published genome sequences for both species, which makes it is easier to identify candidate genes. These species are …

Amp Expression In Energetic Hybrid D. Melanogaster Infected With P. Rettgeri, Cassandra K. Treu, Justin Buchanan, Kristi Montooth

UCARE Research Products

The purpose of this experiment was to investigate immune function and energy metabolism, particularly the levels of antimicrobial peptides produced in Drosophila energetically compromised genotypes. This will provide the ability to investigate energetics of immunity without changing diet. Flies were infected with the bacteria P. rettgeri and the resulting immune response was investigated. Females did not mount as effective an immune response as males. All flies exhibited decreased survivorship from infection. Control flies survived at higher levels and showed no mitochondrial:nuclear interaction.

Using Alien Resources: Caribbean Dwarf Geckos Nesting Communally In Invasive Flora, Justin M. Bernstein, Aaron H. Griffing, Juan D. Daza, Tony Gamble, Aaron M. Bauer

Biological Sciences Faculty Research and Publications

No abstract provided.

Lactate Dehydrogenase Is Crucial For Tumor Associated Macrophage Protection Of Multiple Myeloma Cells Against Chemotherapy, Carolyn Stierhoff

Celebration of Scholarship 2012-2017

Multiple myeloma (MM) is a cancer characterized by an accumulation of malignant plasma cells in the bone marrow. Although chemotherapy is the most effective treatment, the majority of patients experience relapse. The major cause of treatment failure is the development of multidrug resistance. Thus, overcoming drug resistance will greatly improve patient survival. The enzyme lactate dehydrogenase (LDH) plays an important role in anaerobic respiration by converting pyruvate into lactate in the absence or low supply of oxygen. It has been observed that tumor-associated macrophages (TAMs) present in tumor environments can protect MM from chemotherapy treatment. We discovered that an LDH …

Epigeal Fauna Of Bosque Protector Cerro Candelaria, Justine Albers

Independent Study Project (ISP) Collection

Pitfall traps are commonly used to sample epigeal fauna, and are especially utilized for the collection of ground-dwelling arthropods; however, this sampling method has yet to be employed in Cerro Candelaria, a protected cloud forest reserve in Tungurahua, Ecuador. Pitfall trap systems were established at two different sites in the reserve that differed in elevation and forest type. Although individuals from 4 different phlya, 11 classes and 17 orders were encountered over the duration of the study, pitfalls were most effective at sampling Coleoptera, which comprised 40% of the total catch across both sites. The two communities of beetle …

Identification And Characterization Of Ion Channel Activity Of The M2 Protein From Influenza Virus D (Dm2), Jianing Liu

School of Biological Sciences: Dissertations, Theses, and Student Research

Viral ion channels are membrane proteins of influenza viruses that play essential roles in the replication cycle, which enables them to be targeted by antiviral drugs. M2 of influenza type A virus, BM2 of influenza type B virus, and CM2 from influenza type C virus have been characterized as ion channel proteins and antiviral drug amantadine was developed to control influenza type A virus. However, few studies have been conducted to clarify the properties of the M2 protein (DM2) of influenza type D virus, a novel influenza virus genus identified in 2014. To identify the ion channel activity of DM2, …

The Influence Of Spines On Predation And Survivorship Of Devonian Brachiopods, Broc S. Kokesh

Undergraduate Research Symposium 2016

Brachiopods are small animals that live on the seafloor and are abundant in the Devonian fossil record (420 to 360 million years ago), making them excellent subjects for studying evolution in ancient marine environments. Some species sported large spines that cover their exterior surfaces, although these spines are typically broken off during fossilization. Paleontologists have hypothesized that these spines developed as an evolutionary response to predation, yet few studies have tested this idea due to the scarcity of specimens with intact spines. Recent work has been able to get around this problem by examining injury markings caused by predators that …

Molecular Analysis Confirming The Introduction Of Nile Crocodiles, Crocodylus Niloticus Laurenti 1768 (Crocodylidae), In Southern Florida, With An Assessment Of Potential For Establishment, Spread, And Impacts., Michael R. Rochford, Kenneth L. Krysko, Frank J. Mazzotti, Matthew W. Shirley, Mark W. Parry, Joseph A. Wasilewski, Jeffrey S. Beauchamp, Christpher R. Gillette, Edward F. Metzger Iii, Michiko A. Squires, Louis A. Somma

Papers in Herpetology

The state of Florida, USA, has more introduced herpetofauna than any other governmental region on Earth. Four species of nonnative crocodilians have been introduced to Florida (all since 1960), one of which is established. Between 2000–2014 we field-collected three nonnative crocodilians in Miami-Dade County, Florida, and one in Hendry County, Florida. We used DNA barcoding and molecular phylogenetics to determine species identification and native range origin. Also, we described diet, movement, and growth for one crocodile. Our molecular analyses illustrated that two of the crocodiles we collected are most closely related to Nile Crocodiles (Crocodylus niloticus) from South Africa, suggesting …

Non-Thermal Atmospheric-Pressure Plasma For Sterilization Of Surfaces And Biofilms, Johanna Ursula Neuber

Electrical & Computer Engineering Theses & Dissertations

Bacterial resistance to antimicrobial methods is a critical issue in many fields of medicine. This work describes the studies performed to characterize and optimize the bacterial inactivation effects of a non-thermal atmospheric-pressure plasma brush and plasma jet on a laminate surface inoculated with Acinetobacter baumannii and Staphylococcus aureus, and a cultivated Enterococcus faecalis biofilm, respectively. These treatments are pilot studies for eventual application to surface sterilization in hospitals and root canal disinfection. To evaluate bacterial inactivation, after treatment and recovery, the bacterial colony forming units (CFUs) are counted. Several different methods are used to optimize the antimicrobial effect. For the …

A Hitchhiker’S Guide To Invasion Biology: Describing The Ecological Mechanisms Underlying The Range Expansions Of Two Ixodid Tick Species, Robyn M. Nadolny

Biological Sciences Theses & Dissertations

Increasing incidence of many tick-borne diseases have been linked to recent expansions of tick species distributions. Many tick species are expanding their ranges because of anthropogenic changes in the landscape, shifting climatic variables, and increasing populations of suitable host species and tick habitat. Few empirical studies have been performed, however, investigating the ecological mechanisms underlying these range expansions. Ticks are parasitic organisms that disperse across landscape by hitchhiking on hosts, but must then survive in the environment for long periods of time between bloodmeals. Two species of ixodid tick, Ixodes affinis and Amblyomma maculatum, are simultaneously expanding their ranges throughout …

Naturalization Of Salt Marsh Restoration Sites In The Elizabeth River, Virginia, Assessed By Feeding Activity And Trophic Level Of Mummichogs (Fundulus Heteroclitus), Moriah Anne Good

Biological Sciences Theses & Dissertations

Recent efforts to mitigate environmental issues within the Southern Branch of the Elizabeth River, Virginia, designated a “Region of Concern” by the Chesapeake Bay Program, include several salt marsh restorations. By examining gut contents and stable isotopes values (δ13C and δ15N) from mummichogs (Fundulus heteroclitus), the functional equivalency of restored salt marshes compared to natural marshes was measured. In July 2013 I collected mummichogs from three restored and three reference salt marshes in the Southern Branch. Fish were collected for gut content analysis and were analyzed for stable isotopes (δ13C and δ15N).

I removed gut contents from 16 fish per …

Anti-Predator Responses Of Squid Throughout Ontogeny, Carly Anne York

Biological Sciences Theses & Dissertations

Multiple sensory modalities and a complex array of escape behaviors have evolved as components of anti-predator responses in squids. The goals of this study include: (1) examine the role of the lateral line analogue and vision in successful predator evasion; (2) measure kinematics of escape jetting; (3) document how chromatic patterning, posturing and inking in squid change in response to predators; and (4) investigate escape jet hydrodynamics of squid. Given that squids undergo considerable morphological, ecological, and behavioral changes throughout ontogeny, the goals above were all investigated across different life history stages. To test the respective roles of vision and …

Characterization Of Soundscapes In Shallow Water Habitats Of The Florida Keys (Usa) And Their Influence On The Settlement Of Larval Fish And Invertebrates, John R. Butler

Biological Sciences Theses & Dissertations

In recent decades, changes in climate and water quality in Florida Bay and the Florida Keys (FL, USA) caused expansive cyanobacteria blooms that in turn precipitated massive sponge die-offs that drastically altered sponge-dominated hard-bottom communities in south-central Florida Bay. This area served as a model system to explore the effect of ecosystem change and habitat restoration on underwater soundscapes and larval recruitment. I had four main objectives: (1) characterize the underwater soundscapes of three near-shore, benthic habitats: mangrove islands, seagrass meadows, and hard-bottom (Chapter 2); (2) quantify larval settlement within healthy, degraded, and restored hard-bottom areas to test whether habitat …

Multivariate Analysis Of Genotype-Phenotype Association, James M. Cheverud, Philipp Mitteroecker, Mihaela Pavlicev

James Cheverud