Physical Sciences and Mathematics Commons^™

Amyloid Aggregation-Mitigating Peptides As Potential Alzheimer's Drugs, Cyrus Kipkurui Bett

LSU Doctoral Dissertations

Neuronal cytotoxicity observed in Alzheimer¡¦s disease (AD) is linked to the aggregation of £]-amyloid peptide (A£]) into toxic forms. Increasing evidence points to oligomeric species as the neurotoxic species compared to fibrils; disruption or inhibition of A£]ƒnself-assembly into oligomeric or fibrillar forms remains a viable therapeutic strategy to reduce A£] neurotoxicity. Amyloid aggregation mitigating peptides (AAMPs) were designed based on the A£]ƒn¡§hydrophobic core¡¨ A£]17-20, with C£\,£\-disubstituted amino acidsƒnƒv£\£\AAs) added into this core as disrupting agents. The number, distribution, and side chain functionality of £\£\AAs incorporated into the mitigator sequence was found influences the resultant aggregate morphology as indicated by ex-situ …

Substituted Bis(Beta-Diketones) For Molecular Squares, Jace Sandifer

LSU Master's Theses

Our group has been synthesizing porous supramolecular metal-organic molecules using multidentate β-diketones as ligands. For example, m-phenylenebis(acetylacetone) (m-pbaH2, 1) and m-phenylenebis(dipropionylmethane) (m-pbprH2, 2) were readily converted to the molecular squares Cu4(m-pba)4 (6) and Cu4(m-pbpr)4 (7), which bind guests such as 4,4’-bpy and C60.1 However, 6 and 7 are only soluble in a few solvents, limiting their use in practical applications. It is therefore necessary to derivatize the ligand with different functional groups in order to improve solubility and adjust host-guest properties. Simple alkoxy derivatives should prove useful in testing this idea as they would be relatively chemically inert and should …

Remediating Impacts Of Global Climate Change-Induced Submergence On Salt Marsh Ecosystem Functions, Camille Lafosse Stagg

LSU Doctoral Dissertations

Impacts of global climate change, such as sea level rise and severe drought, have altered the hydrology of coastal salt marshes resulting in submergence and subsequent degradation of ecosystem function. A potential method of rehabilitating these systems is the addition of sediment-slurries to increase the elevation of the marsh surface, thus ameliorating the effects of excessive inundation. Although this technique is growing in popularity, the successful restoration of ecological function after sediment addition has received little attention. The purpose of this research was to determine if sediment subsidized salt marshes are functionally equivalent to natural marshes and whether salt marshes …

Convolution Semigroups, Kevin W. Zito

LSU Doctoral Dissertations

In this dissertation we investigate, compute, and approximate convolution powers of functions (often probability densities) with compact support in the positive real numbers. Extending results of Ursula Westphal from 1974 concerning the characteristic function on the interval $[0,1]$, it is shown that positive, decreasing step functions with compact support can be embedded in a convolution semigroup in $L^1(0,infty)$ and that any decreasing, positive function $pin L^1(0,infty)$ can be embedded in a convolution semigroup of distributions. As an application to the study of evolution equations, we consider an evolutionary system that is described by a bounded, strongly continuous semigroup ${T(t)}_{tgeq0}$ in …

Cbod₅ Treatment And Nitrogen Transformations Of The Marshland Upwelling System In Intermediate And Saltwater Marshes, Lorna Anne Putnam

LSU Doctoral Dissertations

The marshland upwelling system (MUS) was designed to treat domestic wastewater from coastal dwellings where conventional methods are inadequate due to high water tables, poor hydraulic soil conditions, anaerobic soils, and saline groundwater. Currently there is no adequate treatment system available and coastal dwellings are contributing to water quality problems. This study focused on determining the treatment effectiveness of the MUS for organic matter and understanding the specific processes involved in nitrogen treatment.

The treatment of organic matter, measured as five-day carbonaceous biological oxygen demand (CBOD₅), was effective in field tests for both saltwater and intermediate marshes. Global …

Integrated Technology: Does It Affect Learner Outcomes?, Adam Ross Barrett

LSU Master's Theses

Because technology has become prevalent in classrooms, this study was undertaken to test whether the use of integrated technology, specifically computers and online activities, affects learner outcomes in a classroom setting. The outcomes from classes taught using integrated technology were compared to classes taught with traditional teaching strategies. Students in a 7th grade life-science class were given pre-tests and post-tests to determine their learning gains on the topics of genetics and photosynthesis. Each class was assigned different activities based on the subject. Each unit was covered in four 90 minute periods. When one set of classes was using integrated technology …

A Study Of The Self-Assembly Of Water-Soluble Porphyrins In Aqueous Solution, Javoris Hollingsworth

LSU Master's Theses

In nature, self-assembly processes of biologically active organic molecules often occur, resulting in formation of dimers and higher oligomers of various and sometimes complex structures. This natural occurrence of self-organization has been the subject of research, with the aim of understanding and possibly modulating the aggregation behavior of biological molecules. The meso-tetrakis(4-phosphonatophenyl) porphyrin, H2TPPP was synthesized, purified, and characterized. Its self-assembly was studied in aqueous solutions as a function of pH and time. The variations on the λmax and shape of the Soret band of this porphyrin in the absorption spectra when altering the pH indicated the pH dependency in …

Translocation Success Of Adult Red-Cockaded Woodpeckers, Erin Herbez

LSU Master's Theses

The red-cockaded woodpecker (Picoides borealis; hereafter RCW) is a cooperative breeder endemic to open old-growth pine savannah ecosystems in the southeastern United States (Jackson 1994). The RCW was listed as federally endangered in 1973, after a population decline due to habitat loss. Habitat fragmentation produces isolated populations of RCWs, which in turn ultimately limits the success of the species. RCW biologists and managers counteract effects of fragmentation by aggregating recruitment clusters and translocation. Although several studies examined subadult RCW translocation, detailed studies examining adult translocation have been limited. My study was conducted on a 3500 ha area owned by Plum …

Holocene Evolution And Avulsion History Of The Lower Mississippi River, Yazoo Basin, Ms, Eric Prokocki

LSU Master's Theses

Optically stimulated luminescence dates coupled with paleohydrological estimations from lower Mississippi River (LMR) meander belts within the Yazoo Basin, MS provide new insight into the geochronological and hydrologic history of the LMR throughout the Holocene period. According to OSL dates, there are only three temporally equivalent LMR meandering river regime sediment packages, and not five as previously assumed from past geochronological research initiatives within the lower Mississippi Valley (LMV). The three geochronological sediment packages from oldest to youngest are thus represented by the following LMR meander belts: Early Holocene Chronostratigraphic Package – ca. 9.19 to 8.07 ka represented by the …

Comparisons Of Boosted Regression Tree, Glm And Gam Performance In The Standardization Of Yellowfin Tuna Catch-Rate Data From The Gulf Of Mexico Lonline [Sic] Fishery, Shane Abeare

LSU Master's Theses

Recent advances in statistical understanding have focused fisheries research attention on addressing the theoretical and statistical issues encountered in standardizing catch-rate data. Similarly, the present study evaluates the performance of boosted regression trees (BRT), the product of recent progress in machine learning technology, as a potential tool for catch-rate standardization. The BRT method provides a number of advantages over the traditional GLM and GAM approaches including, but not limited to: robust parameter estimates as a result of the integrated stochastic gradient boosting algorithm; model structure learned from data and not determined a priori, thereby avoiding assumptions required for model specification; …

M. Effects Of Land Use And Habitat On Stream Fish Assemblages In Tributaries Of The Lower Bogue Chitto Watershed, Washington Parish, Louisiana, Brian Michael Ward

LSU Master's Theses

My research focused on how fish communities are responding to watershed land use and instream habitat in tributaries of the Lower Bogue Chitto River. To address this question I electrofished and seined 10 sites in four tributaries of the Bogue Chitto River a total of 4 times each over the course of 15 months in 2007 and 2008. I characterized habitat by measuring water flow, water depth, substrate size, woody debris, temperature, and dissolved oxygen, and quantified heterotrophic plate counts, nutrients, and chlorophyll a concentrations at the end of the sampling period each year. Watershed land cover was measured with …

Role Of Shelf Morphology In Grounding-Line Stability: A Numerical Approach, Rhonika Robinson

LSU Master's Theses

The main concern of this study is to discover how the transition from a shallow to an overdeepened, foredeepened shelf might affect grounding-line translation of the West Antarctic Ice Sheet (WAIS). Deep shelves permit a larger influx of relatively warm Circumpolar Deep Water (CDW), which melts the ice at grounding lines, and thereby, create a potentially unstable situation in which ice retreat may accelerate. Numerical analysis of the responses of marine ice sheets on various shelf profiles confirmed that a change in shelf morphology changes ice sheet dynamics. Ice sheet retreat on an overdeepened, foredeepened shelf is, at least, 3 …

Seasonal Variability In Absorption And Fluorescence Properties Of Chromophoric Dissolved Organic Matter In The Barataria Basin, Louisiana, Usa, Shatrughan Singh

LSU Master's Theses

Absorption and fluorescence measurements of chromophoric dissolved organic matter (CDOM) were examined along a transect containing 36 sampling stations in the Barataria Basin during high and low conditions to observe seasonal variation in these optical properties. The objectives of this study were (i) to observe CDOM variability in Barataria Basin in variable flow (high and low) conditions, and to characterize the CDOM, (ii) to identify the constituents of CDOM and to model CDOM compositional variability in the Barataria Basin using parallel factor analysis (PARAFAC). CDOM–salinity relationships were non-conservative in lower and upper part of the transect; however a conservative inverse …

Subaqueous, Hurricane-Initiated Shelf Failure Morphodynamics Along The Mississippi River Delta Front, North-Central Gulf Of Mexico, Walter Scott Guidroz

LSU Doctoral Dissertations

Seafloor instability along the Mississippi River Delta Front (MRDF) gained renewed attention with the landfall of Hurricanes Ivan (2004) and Katrina (2005). Traditional root causes for MRDF shelf failure were exacerbated by sea-state conditions associated with these severe tropical cyclones and their interaction with the seafloor. These conditions were characterized by large waves, long wave periods and wave-induced turbulence in the bottom boundary layer and throughout the water column. An evaluation of local and regional MRDF bathymetry data revealed substantial changes in seafloor elevation and the immediate subsurface sediment profile, hypothesized as the end result of cyclic wave-seafloor interaction, seafloor …

Studies On The Effect Of Natural Organic Matter And Hydration On The Sorption And Desorption Of Trifluorinated Pesticides, Charisma Vinarao Lattao

LSU Doctoral Dissertations

This work was done in order to deepen our molecular level understanding of how soil organic matter (SOM) is assembled in a whole soil and to provide further insight on the effect of SOM assembly on the uptake and release of hydrophobic organic compounds. Various techniques, including ultraviolet absorbance, fluorescence, and total carbon analysis, demonstrate that hydration/solvation of SOM is kinetically controlled. Initial wetting of a soil releases the hydrophobic moieties that are located at the outer surface of SOM, and longer wetting times exfoliate more hydrophobic quinone type moieties that are present in the middle layer, which in turn …

Matter Sources Interacting With A Black Hole: Dynamics And Observable Signatures, Miguel Megevand

LSU Doctoral Dissertations

Dynamical systems involving black holes are one of the most promising sources of detectable gravitational waves. Additionally, one expects strong electromagnetic signals whenever matter sources are present. In this dissertation, we study different astrophysical scenarios pertaining the interaction of matter with a black hole. We first investigate the possibility to localize scalar field configurations surrounding a (dynamic) black hole. The analytical study is illustrated by performing numerical simulations that show the evolution of a Klein-Gordon-like scalar field shell surrounding a black hole. Second, we present a method to estimate the gravitational wave frequency at the end of the inspiral phase …

The Influence Of Familism On Descriptive And Injunctive Norms In Predicting The Intention To Eat A Vegetarian Diet Among Chinese Seventh-Day Adventists, See Wei Toh

Loma Linda University Electronic Theses, Dissertations & Projects

According to the theory of planned behavior (TpB), one determinant of intention to engage in a behavior is the subjective norm. Various studies have found that subjective norm is often the weaker predictor of intention compared to perceived behavioral control and attitude. This study examined whether familism (emphasis on the family rather than the individual) would contribute positively to the predictive power of the TpB model through interactions with the family portion of descriptive and injunctive norms. Descriptive and injunctive norms are component variables of the subjective norm. A sample of 284 adult Chinese Seventh-day Adventists 18 years and older …

Patterns Of Spiny Lobster (Panulirus Argus) Postlarval Recruitment In The Carribbean: A Crtr Project, Mark J. Butler Iv, Angela M. Mojica, Eloy Sosa-Cordero, Marines Millet, Paul Sanchez-Navarro, Miguel A. Maldonado, Juan Posada, Bladimir Rodriguez, Carlos M. Rivas, Adrian Oviedo, Marcio Arrone, Martha Prada, Nick Bach, Nilda Jimenez, Maria Del Carmen Garcia-Rivas, Kirah Forman, Donald C. Behringer Jr., Thomas Matthews, Claire Paris, Robert Cowen

Biological Sciences Faculty Publications

As part of the Coral Reef Targeted Research (CRTR) Program, a partnership between the Global Environment Facility and the World Bank, our research team examined the recruitment patterns of Caribbean spiny lobster (Panulirus argus) postlarvae among regions in the Caribbean, with a particular focus on Mesoamerica. Our goal was to collect comparable information on postlarval supply among regions and to provide data to test predictions of connectivity generated from a coupled biophysical oceanographic model of lobster larval dispersal. Here we present the results of the postlarval recruitment monitoring program. We monitored the catch of postlarvae on Witham-style collectors …

Dc Electrokinetic Transport Of Cylindrical Cells In Straight Microchannels, Ye Ai, Ali Beskok, David T. Gauthier, Sang W. Joo, Shizhi Qian

Biological Sciences Faculty Publications

Electrokinetic transport of cylindrical cells under dc electric fields in a straight microfluidic channel is experimentally and numerically investigated with emphasis on the dielectrophoretic (DEP) effect on their orientation variations. A two-dimensional multiphysics model, composed of the Navier-Stokes equations for the fluid flow and the Laplace equation for the electric potential defined in an arbitrary Lagrangian-Eulerian framework, is employed to capture the transient electrokinetic motion of cylindrical cells. The numerical predictions of the particle transport are in quantitative agreement with the obtained experimental results, suggesting that the DEP effect should be taken into account to study the electrokinetic transport of …

Is Seagrass An Important Nursery Habitat For The Caribbean Spiny Lobster, Panulirus Argus, In Florida?, Donald C. Behringer, Mark J. Butler Iv, William Herrnkind, John H. Hunt, Charles A. Acosta, William C. Sharp

Biological Sciences Faculty Publications

Caribbean spiny lobster (Panulirus argus) settle preferentially in macroalgal-covered hard-bottom habitat, but seagrass is more prevalent in Florida (United States) and the Caribbean, so even low settlement of lobsters within seagrass could contribute substantially to recruitment if post-settlement survival and growth were high. We tested the role of seagrass and hard-bottom habitats for P. argus recruitment in three ways. We first explored possible density-dependent regulation of early benthic juvenile lobster survival within cages deployed in seagrass and hard-bottom habitats. Second, we compared settlement and survival of P. argus in both habitats, by comparing the recovery of microwire-tagged early …

The Effects Of Climate Change On Biodiversity: Pressing Issues And Research Priorities, Friedhelm Krupp, Lytton J. Musselman, Mohammed M.A. Kotb, Ilka Weidig

Biological Sciences Faculty Publications

No abstract provided.

Coarser Connected Topologies And Non-Normality Points, Lynne Yengulalp

Mathematics Faculty Publications

We investigate two topics, coarser connected topologies and non-normality points. The motivating question in the first topic is:

Question 0.0.1. When does a space have a coarser connected topology with a nice topological property? We will discuss some results when the property is Hausdorff and prove that if X is a non-compact metric space that has weight at least c, then it has a coarser connected metrizable topology. The second topic is concerned with the following question:

Question 0.0.2. When is a point y ∈ β X\X a non-normality point of β X\X? We will discuss the question in the …

Discrete Fractional Calculus With The Nabla Operator, Ferhan M. Atici, Paul W. Eloe

Mathematics Faculty Publications

Properties of discrete fractional calculus in the sense of a backward difference are introduced and developed. Exponential laws and a product rule are developed and relations to the forward fractional calculus are explored. Properties of the Laplace transform for the nabla derivative on the time scale of integers are developed and a fractional finite difference equation is solved with a transform method. As a corollary, two new identities for the gamma function are exhibited.

A Phenomenographic Study Of Introductory Physics Students: Approaches To Problem Solving And Conceptualisation Of Knowledge., Laura Walsh

Doctoral

This phenomenographic study presents a description of the approaches to problem solving and conceptualisation of physics knowledge of introductory physics students, specifically in the context of the Irish higher education system. Much research has been carried out that has shown that physics students are not developing the conceptual knowledge necessary to become adept problem-solvers. This may be due to the traditional physics education assumption that students will develop an understanding of the conceptual nature of physics by repetitively solving quantitative problems. However, research has shown that this is not the case and that education and the curriculum needs to explicitly …

Holographic Liquid Crystal Devices, Kotakonda Pavani

Doctoral

Liquid crystals have become natural candidates for use in electro-optic devices for their ability to change the orientation of the director with the application of an electric field, and exhibiting large range of refractive index. The aim of the work presented in this thesis is to fabricate liquid crystal optoelectronic devices such as electrically switchable liquid crystal diffraction gratings and polarization rotators by exploiting the holographic surface relief effect in photopolymer and by developing novel polymer dispersed liquid crystals (PDLCs). Alignment of liquid crystals is commercially achieved by creating grooves on a conducting layer such as polyimide or indium tin …

Quantitative Analyses Of Dispersion, Doping And Electronic Separation Of Single Wall Hipco Carbon Nanotubes, Priya Baskar Rao

Doctoral

As prepared SWNTs are obtained in bundles with a mixture of both metallic and semi conducting tubes. For many specific applications, electronically separated single individual tubes are required and in order to reach these application criteria, the tubes should be processed. This thesis reports on a systematic exploration of methods to routinely process, electronically separate and characterise commercially available single walled carbon nanotubes (SWNTs). Commercially available HiPco SWNTs were dispersed in water with the assistance of 1 % by weight sodium dodecyl benzene sulphate (SDBS). The tubes were dispersed in the water surfactant system through the aid of sonication and …

Enhanced Absorption Metal Oxides For Photocatalytic Applications, Reenamole Georgekutty

Doctoral

Environmental pollution and industrialization on a global scale has drawn attention to the vital need for developing new hygienic and environmentally friendly purification technologies. The most common indoor and outdoor purification process have their corresponding limitations of electricity and/or other energy sources. To address such enormous tasks, advance oxidation technology like heterogeneous photocatalytic systems via metal oxide semiconductors such as TiO2, ZnO, that are capable to operate effectively and efficiently under UV and visible light must be established. Due to the wide band gap of semiconductors, they are unable to absorb visible light. Hence, numerous research efforts have been done …

Two Component Integrable Systems Modelling Shallow Water Waves: The Constant Vorticity Case, Rossen Ivanov

Articles

In this contribution we describe the role of several two-component integrable systems in the classical problem of shallow water waves. The starting point in our derivation is the Euler equation for an incompressible fluid, the equation of mass conservation, the simplest bottom and surface conditions and the constant vorticity condition. The approximate model equations are generated by introduction of suitable scalings and by truncating asymptotic expansions of the quantities to appropriate order. The so obtained equations can be related to three different integrable systems: a two component generalization of the Camassa-Holm equation, the Zakharov-Ito system and the Kaup-Boussinesq system. The …

The Epidemiological Status Of Pav1, And The Effects Of Infection On Caribbean Spiny Lobster (Panulirus Argus) Condition, Olfaction, And Predation Risk, Donald C. Behringer, Mark J. Butler Iv, Jeffrey D. Shields

Biological Sciences Faculty Publications

No abstract provided.

Mapping The Dark Side With Deimos: Globular Clusters, X-Ray Gas, And Dark Matter In The Ngc 1407 Group, Aaron J. Romanowsky, J. Strader, L. Spitler, R. Johnson, J. P. Brodie, D. A. Forbes, T. Ponman

Aaron J. Romanowsky

NGC 1407 is the central elliptical in a nearby evolved group of galaxies apparently destined to become a galaxy cluster core. We use the kinematics of globular clusters (GCs) to probe the dynamics and mass profile of the group's center, out to a radius of 60 kpc (~10 galaxy effective radii)—the most extended data set to date around an early-type galaxy. This sample consists of 172 GC line-of-sight velocities, most of them newly obtained using Keck/DEIMOS, with a few additional objects identified as dwarf-globular transition objects or as intragroup GCs. We find weak rotation for the outer parts of the …