Digital Commons Network^™

"Frontline In Mental Healthcare": A Discourse Analytic Clinical Ethnography Of Crisis Intervention Team Trainings For Corrections, Daniel Gruner

Electronic Theses and Dissertations

Throughout the criminal justice system operates a discourse of corrections-reform. This responds to prisoner trauma and resistance by converting them into reforms that strengthen prisons and the larger carceral system while discounting issues of race and class that might undermine institutional legitimacy. The recent adoption of Crisis Intervention Team (CIT) Trainings in corrections is exemplary of corrections-reform discourse. ‘Crisis’ comes from the Greek krinein, meaning ‘to decide.’ The crisis in mental health in prisons involves deciding when to implement what “services” or “programming” for whom.

In this discourse analytic clinical ethnographic study, I focus on the trans-disciplinary corrections …

God, Land, Identity: Divine Fluidity And A Spatial Ecclesiology In West Africa, Clement Kanu

Electronic Theses and Dissertations

African theology is burdened with a major problem of identity, which stems from the lack of African history and memory in African theology. African theologians in the face of the delicate dilemma of creating a theology that is both African and Christian, have fallen into the epistemological compulsion to impose western Christian theological categories as foundational to African theology. Inculturation thus presupposes the already alien space on which the structures of the present ecclesiology is anchored. The result is a peripheral inculturation, a consumer ecclesiology, always seeking to solve its local pastoral problems in accordance with alien incongruous codes and …

Bureaucratic Modernity And The Erosion Of Practical Reason: A Rhetorical Education As An Antidote, David Impellizzeri

Electronic Theses and Dissertations

To what extent and in what ways does modernity reveal itself through the bureaucratic? This project aims at an interpretive understanding of bureaucratic modernity. The rationalization of society and action in the (late) modern world requires that an increasing number of human activities and domains be explained in allegedly neutral, ‘rational’ terms and without reference to morally substantive ends. Ultimately, this entails a form of epistemic reductionism that elevates instrumental rationality to the exclusion of practical reason and probabilistic ways of knowing. Bureaucratic modernity signifies a decrease in choices that can be legitimized in public on some basis other …

An Exploration Of Motivational Interviewing And Strengths-Based Supervision To Improve Client Session Attendance, Jeremy Abel

Electronic Theses and Dissertations

Clients missing outpatient psychotherapy sessions is a problem that impacts clients, clinicians, and clinics. Scholarly research has shown that clinicians’ use of Motivational Interviewing (MI) may help to increase attendance rates and that most often MI training is done through a single training or workshop, which may not be a sufficient means to adequately prepare clinicians to effectively use MI. The purpose of this study was to determine whether using every other week, MI-focused, strength-based group supervision after an initial MI training can increase client attendance in two community outpatient substance use disorder and mental health treatment clinics. This study …

Voices On The Horizon: A Theory Of Ludic Rhetoric, Jeff Lohr

Electronic Theses and Dissertations

Voices on the horizon: A theory of ludic rhetoric begins with the assumption that rhetoric and play offer hope for cooperation and community in a fragmented and divided world. Rhetoric and play share an intellectual trajectory in the history of ideas. The earliest use of the terms rhetor and rhetoric in the Western tradition encouraged playful cooperation. The move toward reason and science during the Enlightenment relegated rhetoric to mere techniques for persuasion and silenced alternative avenues for seeking truth. Reclaiming traditional rhetoric as a meeting place for potential negotiation and cooperation encourages constructive civic discourse. The conclusion of this …

A Study Of Chloride Levels In Pine Creek, Allegheny County, Pa, Selina Prettner

Electronic Theses and Dissertations

Pine Creek is a 22.8-mile long tributary to the Allegheny River draining over 67 square miles of northern Allegheny County, PA. The main stem runs along Route 8 and receives extensive runoff from road salt from deicing. A site near Etna, PA sampled biweekly in 2013 consistently showed elevated conductivity that correlated with increased chloride levels. Winter road deicing runoff produced acute chloride concentrations up to 678 mg/L. Chloride fluctuated in the summer and autumn months but did not exceed the USEPA Secondary Drinking Water Standard (250 mg/L) or the aquatic life criterion for chronic concentrations (230 mg/L). Sampling throughout …

Genetic Analysis Of A Novel Ftsk Homolog, Hfka, In Streptomyces Coelicolor Development-Associated Chromosome Segregation, Sumedha Sethi

Electronic Theses and Dissertations

A quintessential phenomenon occurring during prokaryotic development is accurate segregation of the replicated genomes into the daughter cells. Key energy-dependent processes like chromosome condensation and subcellular partitioning of the genomes are driven by conserved proteins like SMC, ParB, FtsK. During its complex developmental cycle, Streptomyces coelicolor segregates its genomes into chains of unicellular spores when its multigenomic syncytial aerial hyphae undergo division.

A novel ftsK-like gene, hfkA (Homolog of FtsK protein A), was examined for function and localization during development-associated chromosome segregation. Individual deletions did not affect segregation, but a ΔhfkA ΔftsK mutant exhibited 8% anucleate …

Greening Of Catalytic Processes Using First-Row Transition Metals For Atom Transfer Radical Addition And Transfer Hydrogenation, Gabrielle Pros

Electronic Theses and Dissertations

This work focused on “greening” catalytic processes, atom transfer radical addition (ATRA), which adds an alkyl halide across and alkene, and transfer hydrogenation/dehydrogenation, which reduces a carbonyl without needing direct H₂ gas. Part of “greening” of these processes is through using abundant first row metals, Cu and Ni for catalysis. One aim was to design new ligands which would be more active in these systems; the second was investigation of additives for catalyst regeneration to reduce the catalyst loading necessary for high yields.

The TPMA^* family was investigated in ATRA. Rate constants followed the expected trend, which increased …

Transcription Regulation Of Human Il1b Gene In Monocytes And Lymphoid Cd4 T Cells, Sree H. Pulugulla

Electronic Theses and Dissertations

Cytokines are key regulators of the inflammatory response and play an important role in facilitating intercellular communication between various immune cell types. Interleukin‑1β (IL‑1β) is a potent pro-inflammatory cytokine that is required for robust initiation of innate immune response and subsequent development of adaptive immunity. IL-1β is first synthesized as an inactive cytoplasmic, non‑glycosylated, precursor molecule (proIL‑1β) by monocytes and macrophages in response to invading pathogenic microbes. The activation of caspase‑1 by inflammasomes cleaves proIL-1β into mature biologically active IL-1β that is released from cells via a non-classical, endoplasmic reticulum‑independent secretory pathway directly from the cytoplasm via Gasdermin D membrane …

State-Dependent Mapping Of Glyr-Cholesterol Interactions By Coupling Crosslinking With Mass Spectrometry, Nicholas Ferraro

Electronic Theses and Dissertations

The glycine receptor (GlyR) belongs to a superfamily of pentameric ligand-gated ion channels (pLGICs) that mediate fast neurotransmission. GlyR typically modulates inhibitory transmission by antagonizing membrane depolarization through anion influx. Allosteric interactions between the receptor and its lipid surroundings affect receptor function, and cholesterol is essential for pLGIC activity. Human α1 GlyR was purified from baculovirus infected insect cells and reconstituted in unilamellar vesicles at cholesterol: lipid ratios below and above the cholesterol activity threshold with aliquots of azi-cholesterol. State-dependent crosslinking studies of receptors primarily in its resting (no glycine), desensitized (10mM glycine) and open (F207A/A288G, 30nM ivermectin) states were …

C-Metalated Nitriles: Diastereoselective Alkylations And Arylations, Robert John Mycka

Electronic Theses and Dissertations

Development of an sp³ hybridized halogen-magnesium exchange route to Grignard reagents, chelation-controlled asymmetric induction of γ- and δ-hydroxynitriles as well as a diastereoselective arylation procedure for C-zincated nitriles have been explored. Sequential addition of i-PrMgCl and n-BuLi to 3- and 4-carbon iodoalcohols triggers a facile halogen-metal exchange to generate cyclic magnesium alkoxides capable of intercepting electrophiles to produce a diverse range of substituted alcohols. This work advances progress toward the synthesis of highly desirable chiral Grignard reagents.

Double deprotonation of γ- and δ-acyclic hydroxynitriles with i-PrMgCl effects highly diastereoselective alkylations via a singly-chelated magnesiated nitriles. …

Genetic And Biochemical Analysis Of A Conserved, Multi-Gene System Regulation Spore-Associated Proteins In Streptomyces Coelicolor, Joseph Sallmen

Electronic Theses and Dissertations

Streptomyces coelicolor is a Gram positive, filamentous soil dwelling bacterium that exhibits a complex life cycle including the transition from a vegetative mycelium to a sporulating, aerial mycelium. Early genetic studies identified two classes of genes that resulted in developmental blocks, bald and white. The bald (bld) phenotype occurs when colonies cannot produce aerial hyphae. White (whi) colonies exhibit incomplete sporulation and/or loss of production of the concurrently produced grey pigment. While some of the original mutants have been explored, the developmental functions of many of the identified genes are not well understood. Of particular interest …

Nanomedicine-Driven Neuropathic Pain Relief In Rat Model Is Associated With Macrophage Polarity And Mast Cell Activation, Muzamil Saleem

Electronic Theses and Dissertations

We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve by using a nanoemulsion-based nanomedicine as a biological probe. The nanomedicine is theranostic: both therapeutic (containing celecoxib drug) and diagnostic (containing near-infrared fluorescent (NIRF) dye) and is small enough to be phagocytosed by circulating monocytes. A model of neuropathic pain is initiated by tying four 1mm spaced knots around the sciatic nerve with chromic gut suture, which results in neuroinflammation, and a resultant pain-like behavior manifests. We show that pain-like behavior reaches a plateau of maximum hypersensitivity 8 days post-surgery, …

Characterization Of The Effect Of Exercise Dose And Integrative Nonpharmacological Therapies In The Treatment Of Chronic Pain, Anna M. Polaski

Electronic Theses and Dissertations

Chronic pain includes debilitating conditions affecting large populations of people throughout the world. These diseases are further complicated by comorbid psychological disorders which make chronic pain conditions difficult to treat. Nonpharmacological treatment options have more recently become an important mainstay of effective therapies and are currently being used to supplement or replace traditional pharmacological treatment methods. Exercise-based therapies in particular are of interest due to their demonstrated success in reducing pain symptoms as well as improving psychological outcomes. Dose is an important factor in being able to effectively prescribe treatments in the context of specific exercise interventions and specific pain …

The Ethical Justification Of Increasing Awareness Of Preventive Medicine Among Healthcare Professionals, Patients And The General Public In The United States, Karishma Ether Moazzam

Electronic Theses and Dissertations

While practiced for centuries, preventive medicine has received increased attention during the recent times. Preventive medicine has a distinct mission to protect, promote, and maintain health as well as to prevent diseases, disabilities, and premature deaths. It aims to fulfill its mission through the combined form of clinical intervention and health promotion. In the recent years, preventive medicine has begun to lean more towards the clinical interventions, taking away from the health promotion. This imbalance has caused preventive medicine to lose its effectiveness in fulfilling its mission. One of the leading causes for such imbalance is the lack of proper …

An Investigation On The Effects Of Cellulose Nanofibrils On The Performance Of Cement Based Composites, Hosain Haddad Kolour

Electronic Theses and Dissertations

Cellulose nanofibrils (CNFs) are hydrophilic biodegradable nanoparticles (typically, less than 0.2 mm in length and 20-50 nm in width) that can be extracted from various plants, trees, and recycled paper stock. Their low density, low toxicity, relatively low cost, high aspect ratio, and high specific surface enable functionalization. In this work, the effects of CNFs on selected properties of cement paste, mortar, and concrete were investigated. For the cement pastes, rheology tests using a simple rheometer showed a reduction in workability as CNF dosage increased. Free shrinkage tests showed an increase in shrinkage at high w/c ratios but a decrease …

Natural Law, The Object Of The Act, And Double Effect: Moral Methodology For Catholic Health Care Ethics, Travis Stephens

Electronic Theses and Dissertations

Pope John Paul II’s Encyclical Veritatis Splendor is the first and only magisterial document that systematically articulates a moral methodology for Catholic moral theology. This dissertation makes explicit the methodological connection between Vatican teaching and the United States Bishops’ Ethical and Religious Directives for Catholic Health Care Services. The thesis of the dissertation explains the systematic connection between Natural Law, the Moral Object of the Act, and the Principle of Double Effect and by extension the ethical Principle of Cooperation. Second, the thesis applies this complex moral method of official teaching to health care ethics.

Following the introduction, chapter …

The Potential For Dickeya Dianthicola To Be Vectored By Two Common Insect Pests Of Potatoes, Jonas K. Insinga

Electronic Theses and Dissertations

Dickeya dianthicola (Samson) causing blackleg and soft rot was first detected in potatoes grown in Maine in 2014. Previous work has suggested that insects, particularly aphids, may be able to vector bacteria in this genus between plants, but no conclusive work has been done to confirm this theory. In order to determine whether insect-mediated transmission is likely to occur in potato fields, two model potato pests common in Maine were used: the Colorado potato beetle (Leptinotarsa decimlineata Say) and the green peach aphids (Myzus persicae Sulzer). Olfactometry and recruitment experiments evaluated if either insect discriminates between infected and …

The Effects Of Sediment Acidification And Temperature On The Immune Capacity Of The Atlantic Jackknife (Razor) Clam (Ensis Leei M. Huber, 2015), Brian Preziosi

Electronic Theses and Dissertations

Sediment acidification has been shown to negatively impact clams of economic importance such as the soft-shell clam, Mya arenaria Linnaeus, 1758, and hard clam, Mercenaria mercenaria (Linnaeus, 1758). Effects of sediment acidification on razor clams, including the Atlantic jackknife clam Ensis leei M. Huber, 2015, are unknown. E. leei has been identified as a species with potential for aquaculture operations on the New England coast. E. leei may be resilient to acidification and thus persist in acidified sediments where other clams cannot. To this end, the impact of acidified surface sediment on the internal immune capacity of adult (mean shell …

Rapid Prototyping To Roll-To-Roll Manufacturing Of Microfluidic Devices, Amber Lee Boutiette

Electronic Theses and Dissertations

Microfluidics constitutes a widely applicable field of enabling technologies with great potential to revolutionize healthcare and biotechnology. The ability to miniaturize and parallelize processes with microfluidics is seen as a solution for many problems with diagnostics technologies and accessibility. Unfortunately, fabricating microfluidics often require extremely expensive, time consuming, and specialized high-precision methods, making both prototyping and commercial-scale mass manufacturing difficult to accomplish. In this work, we evaluate the feasibility of using a unique roll-to-roll (R2R) micropatterning manufacturing process coupled with Additive Manufacturing (3D printing) to rapidly prototype and produce microfluidic devices at high-volume on film or paper backings for applications …

Validation Of A Fluorescence-Based Bacteria Enumeration And Viability Determination Method Using Image Cytometry, Matthew R. Hodgkin

Electronic Theses and Dissertations

Craft beer production in the United States has been increasing significantly in recent years. As production and participation in the industry increases, so have consumer demands for more beer options. Breweries have met this call with experimentation of ingredients in their beer and also the styles they brew. One such beer, the sour beer, is an example of this experimentation and new product development. Sour beers are a style that differ from most other beers by how they are manufactured. Instead of being fermented with only yeast, both a lactic acid-producing bacteria and yeast are used. With increased competition amongst …

Design, Synthesis, & Biological Evaluation Of Novel Het-Aromatic/Aromatic Analogs For The Treatment Of Hiv, Cancer, & Cognitive Dysfunctions, Mohit Gupta

Electronic Theses and Dissertations

Cyclophilin A are a class of peptidyl-prolyl isomerases that catalyzes isomerization of the proline residue within a protein. Cyclophilin A plays an instrumental role in the pathogenesis of HIV and HCV virus. Using structure-based drug we designed and synthesized small molecule inhibitors of cyclophilin A. These inhibitors were biologically evaluated for their ability to inhibit WT HIV-1 inhibition.

Mitogen-Activated Protein Kinase signaling cascades plays a critical role in cancer cell survival, metastasis, and chemo-resistance. The MEK5/ERK5 pathway, which is a member of MAPK signaling cascade, is involved in cell survival, anti-apoptotic signaling, angiogenesis, and cell motility. It is found to …

A Laboratory Investigation Of Cement Based Materials With Cellulose Nanofibers, Parivash Takasi

Electronic Theses and Dissertations

Cellulose Nanofibers (CNFs) are used as additives in cement-based products to modify their properties. Recent studies about the effects of CNFs on cement paste showed inconsistent results for several different important properties, including compressive strength and free shrinkage. There is reason to believe that the unsystematic results of the compressive strengths were affected by the lack of uniform dispersion of CNFs. As a potential remedy, two different mixing methods were applied. The first method used a basic mixer, but aggregates were added to the cement paste mixture to improve the blending process. The second method utilized a high-speed shear mixer …

A Qualitative Representation Of Spatial Scenes In R2 With Regions And Lines, Joshua Lewis

Electronic Theses and Dissertations

Regions and lines are common geographic abstractions for geographic objects. Collections of regions, lines, and other representations of spatial objects form a spatial scene, along with their relations. For instance, the states of Maine and New Hampshire can be represented by a pair of regions and related based on their topological properties. These two states are adjacent (i.e., they meet along their shared boundary), whereas Maine and Florida are not adjacent (i.e., they are disjoint).

A detailed model for qualitatively describing spatial scenes should capture the essential properties of a configuration such that a description of the represented objects …

Evaluating The Occurrence Of Age-Related Peripheral Neuropathy In Het3 Mice And Development Of A Whole Tissue Imaging Technique For Analyzing Total Innervation In The Subcutaneous Adipose Depot, Jake Willows

Electronic Theses and Dissertations

Adipose tissue can be characterized as either being a white (energy storing) depot or a brown (energy expending) depot and both have been found to contain dense networks of neural innervation. This adipose nerve supply regulates numerous metabolic functions and likely plays an important role in the function of adipose blood vessels. Recently our lab has shown in the C57BL/6 mouse model that peripheral neuropathy, or the dying back and dysfunction of the nerves in the superficial tissues such as the skin, can extend into the subcutaneous adipose tissue in conditions commonly associated with the neuropathic phenotype (i.e. diabetes, obesity, …

Student Retention, Coping, And Communication: A Study Of Student Responses To A Common Read At A Small Liberal Arts College, Debbie Cunningham

Electronic Theses and Dissertations

College student retention has been researched for over half a century. Much of the research about student retention has examined easily quantifiable factors, such as demographic variables, or presumably objective measures of student readiness, such as SAT scores. The results of these types of studies demonstrate the complexities of retention and attrition and underscore the importance of examining retention within the local contexts of institutions.

This study adopts a communication perspective to examine the intersection of three critical constructs: student retention, student writing, and identity. By observing the ways in which students constitute their identities in essays submitted as part …

The Effects Of Timber Harvesting On Blacklegged Tick (Ixodes Scapularis) Abundance And Infection Prevalence, Christine Conte

Electronic Theses and Dissertations

The northern range of the blacklegged tick (Ixodes scapularis) is expanding, and with it, the pathogens it vectors, including Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti. As the range of I. scapularis expands, understanding the impacts of land management practices on tick habitat and the wildlife communities that impact pathogen transmission may lead to vector-borne disease management. To determine the effects of timber harvesting on tick abundance and pathogen prevalence, for two consecutive years, we conducted an observational field study at five study sites in Hancock County, Maine, a hotspot of Lyme disease incidence in humans. Each study site consisted …

Bridging The Gap: Including Cultural Science In Post-Secondary Education To Enhance Learning Within Sciences For Native And Non-Native Students, Tish Carr

Electronic Theses and Dissertations

Until seven years ago, there were few mechanisms in place within theWabanaki communities to keep Native students connected from middle school through college if an interest was sparked in the science, technology, engineering and math (STEM) fields. On average, less than 50 percent of Native Students graduate from high school. The past six years, the Wabanaki Youth in Science program (WaYS) has become a "bridge" for students to learn more at the secondary level about STEM fields. The next phase in the academic journey to aid student learning is to develop a model educational program that will increase Native youth …

Have Teacher Scholarship Programs Impacted The Critical Teacher Shortage In Mississippi?, Jensen Bosarge Jacquet

Electronic Theses and Dissertations

This research focused specifically on the impact and effectiveness of the Mississippi Excellence in Teaching Program (METP), the only teacher scholarship program currently offered in the state of Mississippi. The first research question asked to what extent METP has impacted the critical teacher shortage in Mississippi, focusing specifically on the impact of the program in attracting students to enter teacher education programs and learning opportunities that have been made available post-college. The second research question asked if METP is likely to continue impacting the critical teacher shortage in Mississippi. As the population size was limited, as well as the sample …

Teacher Professional Development Using Iterative Inquiry-Based Chemistry Workshop, Clint Eaton

Electronic Theses and Dissertations

The National Science Teachers Association recommends that all science teachers use instructional practices that support scientific inquiry, in alignment with Next Generation Science Standards that integrate content with inquiry practices. However, research has shown that many science teachers do not have robust understandings and experiences of scientific inquiry or may not manifest it successfully in their classroom practices. This study investigates teachers’ learning of inquiry elements including scientific communication skills and evidence and reasoning to support claims, through the use of iterative inquiry-based chemistry activities. The study was conducted during Professional Development (PD) in the context of a rural Mathematics …