Small or Companion Animal Medicine Commons^™

Canine Emotions As Seen Through Human Social Cognition, Miiamaaria V. Kujala

Animal Sentience

It is not possible to demonstrate that dogs (Canis familiaris) feel emotions, but the same is true for all other species, including our own. The issue must therefore be approached indirectly, using premises similar to those used with humans. Recent methodological advances in canine research reveal what dogs experience and what they derive from the emotions perceptible in others. Dogs attend to social cues, they respond appropriately to the valence of human and dog facial expressions and vocalizations of emotion, and their limbic reward regions respond to the odor of their caretakers. They behave differently according to the …

Clinical Study Of Canine Tear Lacritin As A Treatment For Dry Eye, Katherine E. Kelly

Senior Honors Projects, 2010-2019

Keratoconjunctivitis sicca (KCS), the deficiency of tears also known as dry eye, is a prevalent disease that affects both humans and canines. The current treatment for dye eye, cyclosporine (Restatis®), only provides temporary relief, is often associated with discomfort and is inconsistently effective. Lacritin is a naturally occurring tear glycoprotein secreted from the human and canine lacrimal glands. It has been shown that lacritin stimulates basal tearing in rabbits when applied topically. This study characterized the amount and form of lacritin found in the tears of dogs with healthy and dry eyes—information which may be applied to the development of …

Animal-Assisted Therapy For Military Veterans With Posttraumatic Stress Disorder: An Investigation On The Positive Effects Of Attachment And Affiliation Behaviors, Sara Miele

Scholarly and Creative Works Conference (2015 - 2021)

Posttraumatic stress disorder (PTSD) develops in people who have experienced a traumatic event (nimh.nih.gov, 2016). Because PTSD is a chronic disorder, it is associated with impaired quality of life (Stern et al., 2013). A specific population at high risk for developing PTSD is military veterans. It is estimated over half a million military veterans suffer from PTSD (Stern et al., 2013). Although there are psychological services and treatments for veterans, many do not seek help because fear of the negative stigma associated with mental illness (Lanning & Krenek, 2013). Recently, efforts have been made to implement veteran friendly treatment in …

Development Of A Novel In Vivo Corneal Fibrosis Model In The Dog, K. M. Gronkiewicz, Elizabeth A. Giuliano, K. Kuroki, F. Bunyak, Ajay Sharma, L. B. C. Teixeira, C. W. Hamm, R. R. Mohan

Pharmacy Faculty Articles and Research

The aim of this study was to develop a novel in vivo corneal model of fibrosis in dogs utilizing alkali burn and determine the ability of suberanilohydroxamic acid (SAHA) to inhibit corneal fibrosis using this large animal model. To accomplish this, we used seven research Beagle dogs. An axial corneal alkali burn in dogs was created using 1 N NaOH topically. Six dogs were randomly and equally assigned into 2 groups: A) vehicle (DMSO, 2 μL/mL); B) anti-fibrotic treatment (50 μM SAHA). The degree of corneal opacity, ocular health, and anti-fibrotic effects of SAHA were determined utilizing the Fantes grading …

Molecular Mechanisms Of Suberoylanilide Hydroxamic Acid In The Inhibition Of Tgf-Β1-Mediated Canine Corneal Fibrosis, Kristina M. Gronkiewicz, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Objective—To investigate molecular mechanisms mediating anti-fibrotic effect of SAHA in the canine cornea using an in vitro model. We hypothesized that SAHA attenuates corneal fibrosis by modulating Smad-dependent and, to a lesser extent, Smad-independent signaling pathways activated by TGF-β1, as well as matrix metalloproteinase (MMP) activity.

Methods—Cultured canine corneal fibroblasts (CCF) were incubated in the presence/absence of TGF-β1 (5ng/ml) and SAHA (2.5μM) for 24hrs. Western blot analysis was used to quantify non-phosphorylated and phosphorylated isoforms of Smad2/3, p38 MAP kinase (MAPK), ERK1/2 and JNK1. Real-time PCR and zymography were utilized to quantify MMP1, MMP2, MMP8 and MMP9 mRNA expression and …

Environmental Salmonella In Agricultural Fair Poultry Exhibits In Colorado, K. L. Pabilonia, K. J. Cadmus, T. M. Lingus, D. S. Bolte, M. M. Russell, D. C. Van Metre, M. M. Erdman

United States Department of Agriculture Wildlife Services: Staff Publications

Salmonella enterica is a common zoonotic pathogen in humans. Transmission typically occurs through consumption of contaminated food products or contact with infected animals, including poultry or their environment. The objective of this study was to estimate the frequency of Salmonella contamination in the environment in poultry exhibits at agricultural fairs. Samples were collected from cages, feed, floors and tables in the exhibit and cultured for Salmonella. At least one environmental sample was positive for Salmonella in 10 of 11 fairs (91%), and Salmonella was isolated from 28 of 55 environmental samples (50.9%). Eleven different serotypes were detected. Results of …

Puppy Buyer Complaints: A Five-Year Summary, 2007‐2011, The Humane Society Of The United States

PUPPY MILL REPORTS

The Humane Society of the United States receives complaints about sick puppies on a daily basis. Over a five-year period (2007-2011), our puppy mills campaign received 2,479 puppy buyer complaints. The complaint came to The HSUS via our website complaint form (www.humanesociety.org/puppycomplaint), by email, and through our puppy mills tip line. Buyers complained about sick puppies sold by a variety of sources, including pet stores, breeders (both in person and online), or middleman dealers (sometimes known as brokers). Unsatisfied buyers contact The HSUS for many reasons; some are seeking information about how to pursue their consumer complaint, others …

Veterinary Problems In Puppy Mill Dogs, The Humane Society Of The United States

PUPPY MILL REPORTS

Dogs in puppy mills often suffer from an array of painful and potentially life-shortening veterinary problems due to overcrowded, unsanitary conditions and the lack of proper oversight or veterinary care. Conditions common to puppy mills, such as the use of stacked, wire cages to house more animals than a given space should reasonably hold, as well as constant exposure to the feces and urine of other dogs, make it difficult for dogs to avoid exposure to common parasites and infectious diseases. In addition, a lack of regular, preventive veterinary care, clean food and water, basic cleaning and grooming, and careful …

Effect Of A Direct-Fed Microbial (Eubios 1090) In The Presence Of Antibiotics (Carbadox Or Ctc-Denagard) On Post-Weaning Pig Growth Performance And Immune Response, Kimberley Santos, Charles Maxwell, Elizabeth Kegley, Charles Rosenkrans

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

A study was conducted to determine the effects of a probiotic (Eubios 1090), in the presence of two different antibiotics, on performance in nursery pigs. A total of 216 pigs were weaned at an average of 21 d, blocked by initial body weight (BW = 6.79 kg), and distributed into 32 pens of 6 to 7 pigs per pen in an offsite nursery facility. Pens were randomly assigned to 1 of 4 dietary treatments (8 pens per treatment) that were fed throughout post-weaning phase 1 (day (D) 0 to 10), phase 2 (D 10 to 20), and phase 3 (D …