Petri Nets As A Unifying Tool To Link Physiologically Based Toxicokinetic (Pbtk) Models To Adverse Outcome Pathways (Aops),
2019
Illinois State University
Petri Nets As A Unifying Tool To Link Physiologically Based Toxicokinetic (Pbtk) Models To Adverse Outcome Pathways (Aops), Ian Edhlund
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Biophysical And Biomechanical Properties Of Neural Progenitor Cells As Indicators Of Developmental Neurotoxicity,
2019
Cleveland State University
Biophysical And Biomechanical Properties Of Neural Progenitor Cells As Indicators Of Developmental Neurotoxicity, Gautam Mahajan, Moo-Yeal Lee, Chandrasekhar R. Kothapalli
Chemical & Biomedical Engineering Faculty Publications
Conventional in vitro toxicity studies have focused on identifying IC50 and the underlying mechanisms, but how toxicants influence biophysical and biomechanical changes in human cells, especially during developmental stages, remain understudied. Here, using an atomic force microscope, we characterized changes in biophysical (cell area, actin organization) and biomechanical (Young's modulus, force of adhesion, tether force, membrane tension, tether radius) aspects of human fetal brain-derived neural progenitor cells (NPCs) induced by four classes of widely used toxic compounds, including rotenone, digoxin, N-arachidonoylethanolamide (AEA), and chlorpyrifos, under exposure up to 36 h. The sub-cellular mechanisms (apoptosis, mitochondria membrane potential, DNA damage, glutathione …
Environmentally Responsible Land Use, Spring/Summer 2010, Issue 22,
2019
University of Louisville
Environmentally Responsible Land Use, Spring/Summer 2010, Issue 22
Sustain Magazine
No abstract provided.
Sustainable Communities, Fall/Winter 2010, Issue 21,
2019
University of Louisville
Sustainable Communities, Fall/Winter 2010, Issue 21
Sustain Magazine
No abstract provided.
Sustainable Building, Spring/Summer 2009, Issue 20,
2019
University of Louisville
Sustainable Building, Spring/Summer 2009, Issue 20
Sustain Magazine
No abstract provided.
Environmental History, Fall/Winter 2009, Issue 19,
2019
University of Louisville
Environmental History, Fall/Winter 2009, Issue 19
Sustain Magazine
No abstract provided.
Student Research, Spring/Summer 2008, Issue 18,
2019
University of Louisville
Evolving Pollution Prevention, Fall/Winter 2008, Issue 17,
2019
University of Louisville
Evolving Pollution Prevention, Fall/Winter 2008, Issue 17
Sustain Magazine
No abstract provided.
Climate Change, Spring/Summer 2007, Issue 16,
2019
University of Louisville
Our Energy Future, Fall/Winter 2007, Issue 15,
2019
University of Louisville
Land Conservation, Spring/Summer 2006, Issue 14,
2019
University of Louisville
Land Conservation, Spring/Summer 2006, Issue 14
Sustain Magazine
No abstract provided.
Pollution And Heart Disease, Fall/Winter 2006, Issue 13,
2019
University of Louisville
Pollution And Heart Disease, Fall/Winter 2006, Issue 13
Sustain Magazine
No abstract provided.
Green Cities, Spring/Summer 2005, Issue 12,
2019
University of Louisville
Global Sustainability, Fall/Winter 2005, Issue 11,
2019
University of Louisville
Global Sustainability, Fall/Winter 2005, Issue 11
Sustain Magazine
No abstract provided.
Environmental Justice, Spring/Summer 2004, Issue 10,
2019
University of Louisville
Environmental Justice, Spring/Summer 2004, Issue 10
Sustain Magazine
No abstract provided.
Kentucky's Environmental Future, Fall/Winter 2004, Issue 9,
2019
University of Louisville
Kentucky's Environmental Future, Fall/Winter 2004, Issue 9
Sustain Magazine
No abstract provided.
Urban Ecology, Spring/Summer 2003, Issue 8,
2019
University of Louisville
Urban Regeneration, Fall/Winter 2003, Issue 7,
2019
University of Louisville
Urban Air Quality, Spring/Summer 2002, Issue 6,
2019
University of Louisville
Sustainability Of Industrialized Agriculture, Fall/Winter 2002, Issue 5,
2019
University of Louisville
Sustainability Of Industrialized Agriculture, Fall/Winter 2002, Issue 5
Sustain Magazine
No abstract provided.
