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Nutrition Derived Advanced Glycation End Products Are Bio-Social Determinants Of Health That Inform On Cancer Disparities, David P. Turner, Victoria J. Findlay, Bradley A. Krisanits 2023 Department of surgery

Nutrition Derived Advanced Glycation End Products Are Bio-Social Determinants Of Health That Inform On Cancer Disparities, David P. Turner, Victoria J. Findlay, Bradley A. Krisanits

Surgery Presentations

Objectives

Through their ability to perpetuate a reactive stroma, the objective was to define the increased nutritional bioavailability of advanced glycation end products (AGEs) as a pro-tumorigenic consequence of interrelated health inequity risk factors that can influence ancestry specific tumor biology.

Methods

In vivo, ex vivo, and in vitro models were used to define the molecular effects of nutrition associated AGEs on the ancestry specific tumor microenvironment and tumor growth.

Results

The PI’s work provides the first in vivo evidence supporting an oncogenic role for AGEs. In mouse allograft models, both the chronic consumption of AGEs and pre-treatment …


Gut Microbial Metabolite Indole: A Stimulator Of Enteroendocrine Cell Differentiation Via Activation Of Aryl Hydrocarbon Receptor, James Hart 2023 Marshall University

Gut Microbial Metabolite Indole: A Stimulator Of Enteroendocrine Cell Differentiation Via Activation Of Aryl Hydrocarbon Receptor, James Hart

Theses, Dissertations and Capstones

Enteroendocrine cells (EECs) regulate energy balance and glucose homeostasis by releasing hormones in response to food intake. Dysregulated EEC differentiation is observed in obesity, while gut microbiota metabolites influence this process. Here, we investigated the role of indole, a biologically active gut microbial metabolite, in EEC differentiation through aryl hydrocarbon receptor (AhR) activation. Human intestinal organoids derived from jejunal mucosal biopsies were exposed to indole. Indole treatment significantly increased mRNA levels of chromogranin A, an EEC marker. The effect was reversed by an AhR antagonist, indicating AhR involvement. Indole also upregulated AhR target gene mRNA levels. These findings highlight the …


Featured Faculty Mentor/Student Team, Gisela Erf, Alessandro Rocchi 2023 University of Arkansas, Fayetteville

Featured Faculty Mentor/Student Team, Gisela Erf, Alessandro Rocchi

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Letter From The Faculty Editor, Beth Kegley 2023 University of Arkansas, Fayetteville

Letter From The Faculty Editor, Beth Kegley

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Effects Of Time-Restricted Feeding And Whey Protein Isolate Supplementation On Dietary Intake, Mood, And Sleep In A 12-Week Randomized Controlled Trial, Sydney E. Boudrey, Aubree L. Hawley 2023 University of Arkansas, Fayetteville

Effects Of Time-Restricted Feeding And Whey Protein Isolate Supplementation On Dietary Intake, Mood, And Sleep In A 12-Week Randomized Controlled Trial, Sydney E. Boudrey, Aubree L. Hawley

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Obesity affects adults in the United States, leading to chronic diseases and reduced well-being. Time-Restricted Feeding (TRF) is a type of dietary intervention lacking current data regarding the effectiveness on facets of well-being. This study’s objective was to determine the effect of time-restricted feeding supplemented with whey protein isolate on food intake, sleep, and mood in overweight or obese adults. Nineteen participants were randomly assigned to the control or experimental group: 1) control, TRF, and 2) experimental, TRF with whey protein supplementation. Participants followed the assigned dietary intervention for 12 weeks. Every 4 weeks (baseline, week 4, week 8, and …


Rice Biomass Response To Various Phosphorus Fertilizers In A Phosphorus-Deficient Soil Under Simulated Furrow-Irrigation, Jonathan B. Brye, Kristofor R. Brye, Diego Della Lunga 2023 University of Arkansas, Fayetteville

Rice Biomass Response To Various Phosphorus Fertilizers In A Phosphorus-Deficient Soil Under Simulated Furrow-Irrigation, Jonathan B. Brye, Kristofor R. Brye, Diego Della Lunga

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Wastewater-recovered phosphorus (P), in the form of the mineral struvite (MgNH4PO4∙6H2O), may provide a sustainable alternative to decreasing rock-phosphate reserves. Struvite can be generated via precipitation methods, potentially reducing the amount of P runoff to aquatic ecosystems. The objective of this greenhouse tub study was to evaluate the effects of chemically and electrochemically precipitated struvite (CPST and ECST, respectively) on aboveground plant response in a hybrid rice cultivar grown using furrow-irrigation compared to other common fertilizer-P sources [i.e., triple super phosphate (TSP) and diammonium phosphate (DAP)] using three replications of fertilizer treatment in a P-deficient silt loam (Typic Glossaqualfs). Aboveground …


Fostering Infant And Toddler Music Competence At The Jean Tyson Child Development Study Center, Ellen Mathews, Laura Herold, Shelley McNally, Donia Timby 2023 University of Arkansas, Fayetteville

Fostering Infant And Toddler Music Competence At The Jean Tyson Child Development Study Center, Ellen Mathews, Laura Herold, Shelley Mcnally, Donia Timby

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

This paper presents a creative research project that introduced musical instruments in an outdoor setting to infants and toddlers ages 0-to-3 years old. It was grounded in research suggesting that music plays a vital component in expanding development in the early childhood years, helping to promote learning across many domains. This project began with a survey distributed to 7 infant and toddler classroom educators, after which responses were analyzed for themes regarding perceived infant interests. Subsequent observations were conducted to evaluate the best fit for the implementation of an outdoor experiential music space. Based on the findings, a developmentally appropriate …


Effects Of Cyclic Heat Stress On The Acute Inflammatory Response In Broilers, Alessandro J. Rocchi, Chrysta N. Beck, Jossie M. Santamaria, Gisela F. Erf 2023 University of Arkansas, Fayetteville

Effects Of Cyclic Heat Stress On The Acute Inflammatory Response In Broilers, Alessandro J. Rocchi, Chrysta N. Beck, Jossie M. Santamaria, Gisela F. Erf

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Heat stress (HS) is a growing concern in broiler production. Little is known regarding the effect of HS on immune function. To examine the effects of HS on innate immunity, the local- and systemic-inflammatory responses to lipopolysaccharide (LPS) were examined in Cobb 500 male broiler chicks reared under thermoneutral (TN) or cyclic HS conditions. Beginning at four days of age, HS birds were subjected to 35 °C from 8:00 a.m. to 10:00 p.m. and TN temperatures from 10:00 p.m. to 8:00 a.m. At 37 days of age, four groups of broilers were formed: LPS-TN (8 broilers), phosphate-buffered saline (PBS)-TN (4 …


An Inclusive Playground For Infant And Toddler Development, Amanda M. Swartz, Jacquelyn D. Wiersma-Mosley, Donia Timby, Shelley McNally, Caitlyn Daniel 2023 University of Arkansas, Fayetteville

An Inclusive Playground For Infant And Toddler Development, Amanda M. Swartz, Jacquelyn D. Wiersma-Mosley, Donia Timby, Shelley Mcnally, Caitlyn Daniel

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

The purpose of this project was to help children reach more developmental goals and to make outdoor play at the Jean Tyson Child Development Study Center more inclusive for all children. Children gain many developmental goals from playing outside and being exposed to other environments as compared to just being inside the classroom. Outdoor play should be as inclusive as indoor play and offer many different activities and outlets, just as the indoor classroom does. The implementation of this service-learning creative project was to add more versatility to the outdoor area at the University of Arkansas Jean Tyson Child Development …


Curriculum Strategy To Increase College Student’S Motivation, Ability And Opportunity Resulting In Reduction In Wasted Food, Sarah D. Brunnig 2023 University of North Florida

Curriculum Strategy To Increase College Student’S Motivation, Ability And Opportunity Resulting In Reduction In Wasted Food, Sarah D. Brunnig

UNF Graduate Theses and Dissertations

Concerns about Food Loss and Waste (FLW) have been rapidly growing worldwide as it came to be understood how the loss of about one-third of the edible food produced globally leads to environmental damage, leads to loss of about USD 1 trillion and keeps food from hungry people. Consumers in developed countries account for the largest majority of food that is wasted. College presents an excellent opportunity to reach young adults as they are developing their identity, self-efficacy and life skills. Utilizing the Motivation-Ability-Opportunity Framework, this research’s overall goal was to find a Curriculum Strategy to engage allied health students …


Dietitians’ Self-Efficacy For Implementation Strategies And Evidence-Based Practice Guideline Implementation Behaviors: A Mixed Methods Study, Lisa Moloney 2023 Northern Illinois University

Dietitians’ Self-Efficacy For Implementation Strategies And Evidence-Based Practice Guideline Implementation Behaviors: A Mixed Methods Study, Lisa Moloney

Graduate Research Theses & Dissertations

Background: Evidence-based practice (EBP) guidelines are valuable tools that can help promote the implementation of research into practice. Implementation of EBP guidelines can improve the standardization and quality of healthcare, but unfortunately, they are not routinely used in daily practice. Evidence-based practice is a core component of nutrition and dietetics practice, yet little is known about registered dietitian nutritionists’ (RDNs’) implementation of EBP guidelines. Purpose: The purpose of this study was to investigate RDNs’ reported self-efficacy for using implementation strategies and their reported implementation behaviors for EBP guidelines. Methods: An explanatory mixed methods study guided by the Theory of Planned …


The Relationship Between Alpha-Defensin 1 And Gut Microbiome Composition In A Population Of Bhutanese Refugee Adults With A High Prevalence Of Type 2 Diabetes, Daisha Alana Drake 2023 University of New Hampshire, Durham

The Relationship Between Alpha-Defensin 1 And Gut Microbiome Composition In A Population Of Bhutanese Refugee Adults With A High Prevalence Of Type 2 Diabetes, Daisha Alana Drake

Honors Theses and Capstones

The New Hampshire Bhutanese refugee population is disproportionately affected by obesity and metabolic disorders such as type 2 diabetes. The gut microbiome is important for overall human health, with high microbial richness and diversity being associated with reduced chronic inflammation and type 2 diabetes risk. Microbial richness and diversity have been shown to decrease in United States (U.S.) immigrant populations, but have not been measured in refugee populations. One of the anti-inflammatory functions of the gut microbiome is related to the production of short-chain fatty acids (SCFAs), which regulate pro-inflammatory cytokine production. Alpha-defensin 1 is an antimicrobial peptide that is …


Maize, Fish, And Leafy Greens: Agricultural Diversity In Rural Zambia, CLAIRE Gillespie 2023 University of Nebraska - Lincoln

Maize, Fish, And Leafy Greens: Agricultural Diversity In Rural Zambia, Claire Gillespie

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

In Zambia, where 40% of children are stunted, there is limited interest in farming among primary school children as they consider their future. As grocery stores replace open-air markets, access to indigenous foods will become more difficult. Although 73 different types of foods were found in open-air markets, Zambian diets tend to be monotonous. Maize is the staple food and maize-based foods such as nshima are consumed daily, perpetuating low nutritional intake. Increasing crop diversity can increase balanced diets in Zambian school children and better support a growing population.


Running From Malnutrition: Zambian Children And Growth In The Eastern And Southern Provinces, Cole Murphy 2023 University of Nebraska-Lincoln

Running From Malnutrition: Zambian Children And Growth In The Eastern And Southern Provinces, Cole Murphy

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Although malnutrition rates remain high in Zambia, there are limited data for primary school children on factors that contribute to poor growth. This study was designed to examine one factor rarely considered in research about stunting, i.e., energy expenditure among primary school children and its contribution to short stature. § §Historically, stunting has been a major public health issue in much of sub-Saharan Africa and continues to yield severe consequences for physical and mental development throughout the lifespan (Iversen et al., 2022). §Both household food insecurity and dietary diversity are significantly associated with stunting in Sub-Saharan Africa (Gassara et al., …


Site-Specific Incidence Rate Of Blastocystis Hominis And Its Association With Childhood Malnutrition: Findings From A Multi-Country Birth Cohort Study, Barbie Zaman Wahid, Ahshanul Haque, Amran Gazi, Shah Mohammad Fahim, Abu Syed Golam Faruque, Mustafa Mahfuz, Tahmeed Ahmed 2023 International Centre for Diarrhoeal Disease Research, University of Nebraska-Lincoln

Site-Specific Incidence Rate Of Blastocystis Hominis And Its Association With Childhood Malnutrition: Findings From A Multi-Country Birth Cohort Study, Barbie Zaman Wahid, Ahshanul Haque, Amran Gazi, Shah Mohammad Fahim, Abu Syed Golam Faruque, Mustafa Mahfuz, Tahmeed Ahmed

Department of Nutrition and Health Sciences: Faculty Publications

In this study, we investigated the potential association between the burden of asymptomatic Blastocystis spp. (Blastocystis hominis) infection and nutritional status among children under 2 years of age using the data collected from 1,715 children from eight distinct geographic locations, including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. Childhood stunting, wasting, and underweight were the outcome variables, and B. hominis infection was the exposure variable of this present study. The presence of B. hominis in nondiarrheal stools was evaluated by TaqMan Array Cards. Site-specific incidence rates were estimated using Poisson regression, and multiple generalized estimating …


The Paradox Of Child Poverty And Welfare, Tirna Purkait 2023 University of Nebraska-Lincoln

The Paradox Of Child Poverty And Welfare, Tirna Purkait

Department of Nutrition and Health Sciences: Faculty Publications

The United States confronts persistent child welfare issues rooted in poverty. The age-old debate vacillates between advocating personal responsibility and bolstering social safety nets. Current welfare programs, aiming to mitigate child poverty, often fall short given the deep nexus of poverty and child maltreatment. This paper probes the intricate ties between child poverty and welfare, emphasizing state legislative variances, inherent system paradoxes, and potential policy enhancements. Exploring historical contexts, existing societal frameworks, and future reforms, this research emphasizes the urgency for all-encompassing solutions. These should tackle poverty’s core while fortifying child welfare, safeguarding the well-being of forthcoming American generations.


Site-Specific Analysis Of The Incidence Rate Of Enterotoxigenic Escherichia Coli Infection Elucidates An Association With Childhood Stunting, Wasting, And Being Underweight: A Secondary Analysis Of The Mal-Ed Birth Cohort, Ahshanul Haque, Sabiha Nasrin, Parag Palit, Rina Das, Barbie Zaman Wahid, Amran Gazi, Mustafa Mahfuz, Abu Syed Golam Faruque, Tahmeed Ahmed 2023 International Centre for Diarrhoeal Disease Research

Site-Specific Analysis Of The Incidence Rate Of Enterotoxigenic Escherichia Coli Infection Elucidates An Association With Childhood Stunting, Wasting, And Being Underweight: A Secondary Analysis Of The Mal-Ed Birth Cohort, Ahshanul Haque, Sabiha Nasrin, Parag Palit, Rina Das, Barbie Zaman Wahid, Amran Gazi, Mustafa Mahfuz, Abu Syed Golam Faruque, Tahmeed Ahmed

Department of Nutrition and Health Sciences: Faculty Publications

Asymptomatic infection by fecal enteropathogens is a major contributor to childhood malnutrition. Here, we investigated the incidence rate of asymptomatic infection by enterotoxigenic Escherichia coli (ETEC) and assessed its association with childhood stunting, wasting, and being underweight among children under 2 years of age. The Malnutrition and Enteric Disease birth cohort study included 1,715 children who were followed from birth to 24 months of age from eight distinct geographic locations including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. The TaqMan array card assay was used to determine the presence of ETEC in the nondiarrheal stool samples collected …


The Inverse Association Between Prebiotic Consumption And Depression Status In American Adult Females, But Not The Greater Population Or In Males: Nhanes 2015-2018, Cassandra L. Boyd 2023 San Jose State University

The Inverse Association Between Prebiotic Consumption And Depression Status In American Adult Females, But Not The Greater Population Or In Males: Nhanes 2015-2018, Cassandra L. Boyd

Master's Theses

It is unknown if a relationship exists between prebiotic intake and depression status. Using 2015-2018 National Health and Nutrition Examination Survey cycles data, adult American estimated mean daily prebiotic intake across demographic groups, gender, and depression status were reported. Additionally, the 10 highest prebiotic content Food and Nutrient Database for Dietary Studies foods were identified. Adults (≥ 18 years) with adequate sleep and at least one day of dietary recall data were included. Participants with excessive alcohol intake, BMI ≤ 18, BMI ≥ 30, or current depression medication use were excluded. The confounding variables were inadequate sleep, unemployment, and age. …


Food Security, Factors Influencing Food Acceptance, And Preferred Food Assistance Delivery Modalities: A Survey Of Students Attending A Medium Sized, Primarily Residential Emerging Research Institution, Amy Caroline Martin 2023 Northern Illinois University

Food Security, Factors Influencing Food Acceptance, And Preferred Food Assistance Delivery Modalities: A Survey Of Students Attending A Medium Sized, Primarily Residential Emerging Research Institution, Amy Caroline Martin

Graduate Research Theses & Dissertations

Food pantries are the most common form of food assistance provided on college campuses. However, there are several barriers that prevent college students from utilizing pantry resources, leading to low campus food pantry utilization and awareness. Barriers, poor pantry utilization, and awareness have been well documented. However, there is little information currently available regarding factors that facilitate college students’ acceptance of food assistance, and the food distribution modalities that food insecure college students prefer. The purpose of this study was to determine these factors and preferences so they may be used to improve food assistance programs on college campuses.To investigate …


The Role That Diet And Lifestyle Factor Plays In An Increased Risk For Cardiovascular Disease In Asians And Pacific Islanders, Ethan Caragan 2023 Dominican University of California

The Role That Diet And Lifestyle Factor Plays In An Increased Risk For Cardiovascular Disease In Asians And Pacific Islanders, Ethan Caragan

Nursing | Student Research Posters

Cardiovascular disease is the leading global cause of mortality, often resulting in heart attacks and strokes due to obstructed blood flow to vital organs. The risk of these events is influenced by dietary choices, smoking, and physical activity. Despite preventative measures, the impact of diet and lifestyle on cardiovascular health varies across ethnic groups. This thesis aims to evaluate how variations in dietary traditions and lifestyle among Asians and Pacific Islanders contribute to increased or decreased cardiovascular disease risks compared to other racial groups. The study focuses on the dietary and lifestyle factors of Asian Americans and Pacific Islanders in …


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