Nutrition Commons^™

Effects Of Consuming Sugar-Sweetened Beverages For 2 Weeks On 24-H Circulating Leptin Profiles, Ad Libitum Food Intake And Body Weight In Young Adults, Desiree M. Sigala, Adrianne M. Widaman, Bettina Hieronimus, Marinelle V. Nunez, Vivien Lee, Yanet Benyam, Andrew A. Bremer, Valentina Medici, Peter J. Havel, Kimber L. Stanhope, Nancy L. Keim

Faculty Research, Scholarly, and Creative Activity

Sugar-sweetened beverage (sugar-SB) consumption is associated with body weight gain. We investigated whether the changes of (Δ) circulating leptin contribute to weight gain and ad libitum food intake in young adults consuming sugar-SB for two weeks. In a parallel, double-blinded, intervention study, participants (n = 131; BMI 18–35 kg/m2; 18–40 years) consumed three beverages/day containing aspartame or 25% energy requirement as glucose, fructose, high fructose corn syrup (HFCS) or sucrose (n = 23–28/group). Body weight, ad libitum food intake and 24-h leptin area under the curve (AUC) were assessed at Week 0 and at the end of Week …

How Minority Parents Could Help Children Develop Healthy Eating Behaviors: Parent And Child Perspectives, Chishinga Callender, Denisse Velazquez, Meheret Adera, Jayna M Dave, Norma Olvera, Tzu-An Chen, Shana Alford, Debbe Thompson

Children’s Nutrition Research Center Staff Publications

Minority children and children living in under-resourced households are at the greatest risk for obesity and diet-related disparities. Identifying effective strategies to reduce these risks is an important step in child obesity prevention. Parents influence the home environment and play a critical role in child obesity prevention. Eighteen parent–child dyads living in under-resourced Houston area communities participated in a mixed methods study (online surveys, telephone interviews). The purpose of the research reported here was to conduct a secondary analysis of the qualitative data to explore Black/African American and Hispanic parent and child perspectives of the ways in which parents could …

Brain Α-Tocopherol Concentration Is Inversely Associated With Neurofibrillary Tangle Counts In Brain Regions Affected In Earlier Braak Stages: A Cross-Sectional Finding In The Oldest Old, J. Tanprasertsuk, T.M. Scott, M.A. Johnson, L.W. Poon, P.T. Nelson, A. Davey, J.L. Woodard, R. Vishwanathan, A.K. Barbey, K. Barger, X.-D. Wang, E.J. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Objectives: Higher vitamin E status has been associated with lower risk of Alzheimer’s disease (AD). However, evidence of the association of vitamin E concentration in neural tissue with AD pathologies is limited. Design: The cross-sectional relationship between the human brain concentrations of α- and γ-tocopherol and the severity of AD pathologies – neurofibrillary tangle (NFT) and neuritic plaque (NP) – was investigated. Setting & Participants: Brains from 43 centenarians (≥ 98 years at death) enrolled in the Phase III of the Georgia Centenarian Study were collected at autopsy. Measurements: Brain α- and γ-tocopherol concentrations (previously reported) …

Holidays And Healthy Choices, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Objectives:

Healthy holiday eating

Incorporating physical activity into the holiday season

Budget friendly healthy holiday ideas

Translating Evidence-Based Guidelines Into Practice—Are We Getting It Right? A Multi-Centre Prospective International Audit Of Nutrition Care In Patients With Foregut Tumors (Inform), Merran Findlay, Judith D. Bauer, Rupinder Dhaliwal, Marian De Van Der Schueren, Alessandro Laviano, Adrianne Widaman, Lisa Martin, Andrew G. Day, Leah M. Gramlich

Faculty Research, Scholarly, and Creative Activity

Malnutrition is highly prevalent in patients with foregut tumors comprising head and neck (HNC) and esophageal (EC) cancers, negatively impacting outcomes. International evidence-based guidelines (EBGs) for nutrition care exist; however, translation of research evidence into practice commonly presents considerable challenges and consequently lags. This study aimed to describe and evaluate current international nutrition care practices compared with the best-available evidence for patients with foregut tumors who are at high risk of malnutrition. A multi-centre prospective cohort study enrolled 170 patients commencing treatment of curative intent for HNC (n = 119) or EC (n = 51) in 11 cancer …

Power Ultrasonication Improves Tenderness And Proteolysis In Beef Steak During Aging, Chandler Stafford

Fall Student Research Symposium 2020

Among the eating qualities attributed to cooked meat, tenderness is considered an essential factor in dictating consumers' overall satisfaction and future purchase. Tenderness can be influenced by several extrinsic and intrinsic factors; however, the extent of postmortem proteolysis that occurs during meat aging is the main contributor to end-product tenderness. The process involves enzymatic degradation of key cytoskeletal proteins and the signaling of cellular apoptosis, which ultimately leads to the breakdown of muscles structural integrity, resulting in tenderization. The calcium-dependent calpain system, specifically calpain-1, has been recognized as the main protease involved in postmortem tenderization. In the presence of calcium, …

Mitochondrial Pyruvate Consumption Decreases Glycolytic Flux In Postmortem Muscle, Natalie Keele

Fall Student Research Symposium 2020

Mitochondrial pyruvate consumption decreases glycolytic flux in postmortem muscleColor, water-holding capacity and tenderness are important aspects of meat quality that are impacted by pH. The pH of meat is primarily determined by the amount of anaerobic glycolysis that occurs postmortem. As glycogen is degraded, it will produce ATP, pyruvate and hydrogen ions that acidify the meat, and this acidification process is essential for proper meat quality development. In the absence of oxygen, pyruvate is converted to lactate to restore NAD+ necessary for further glycolysis. In this state of anoxia, mitochondria are often ignored due to their reliance on oxygen to …

Cytokine Indicators Of Inflammation In Mice Fed A Western Type Diet, Emily Mortensen

Fall Student Research Symposium 2020

Colorectal cancer is currently the second leading cause of cancer-related deaths in the United States and is projected to cause 53,200 deaths during 2020. The risk of colon cancer increases by 8-20% in individuals who suffer from colitis, which is inflammation of the colon lining. Colitis is common in patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. The development of colorectal cancer is complex and can be associated with dysbiosis of the gut microbiota, which has been shown to be affected by diet. Disruption of the gut microbiome can lead to the overgrowth of pathogenic bacteria …

Belief, Virtue, And Illness In Late-Nineteenth Century Domestic Manuals, Anneka Walton

Fall Student Research Symposium 2020

The belief that one's health is a result of their behavior has persisted throughout much of history. At times, these beliefs were so direct as to blame any and all illness on the "sins" of the victim. In some ways, we still see these beliefs persist today. While we now understand many of the true causes of illness, we continue to believe that poor behaviors can result in poor health outcomes, and often treat people suffering from conditions they "brought on themselves" accordingly. The object of this research is to better understand how American societal beliefs of the causes of …

Diet And Successful Aging, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Learning Objectives:

Define successful aging

Understand the components of successful aging

Learn diets and dietary patterns for successful aging

Physical activity and successful aging

Understanding Caffeine Vs. Kids, Cindy Nelson, Rachel Mcmaster

All Current Publications

Children enjoy numerous foods and drinks on a regular basis that contain caffeine: soda, chocolate candy, energy drinks, and so forth. In fact, almost 3 out of 4 children consume caffeine regularly (American Academy of Family Physicians, 2020). This is a concern because studies show caffeine can affect children and adults differently, and too much caffeine can have detrimental health effects on kids. This fact sheet defines caffeine, reviews its effects and risks, identifies popular foods containing caffeine, and how to reduce consumption of caffeine.

Relationship Between Disordered Eating Risk & Body Image Dissatisfaction Of Spirit Squad Members, Sarah Abdul Albandar

Graduate Theses

Background: Investigations into body image and disordered eating habits among aesthetic sports has shown that these athletes face pressures to be thin and to be a certain body type for their sport.

Research aim/question(s): This study sought to determine if disordered eating habits and body dissatisfaction were prevalent within this population, whether or not there is a relationship between body image and disordered eating, and to determine the current research gap on body image and disordered eating among cheerleaders and dancers.

Materials and Methods: Participants were 23 females including cheerleaders and dancers on the Spirit Squad as well as dance …

Zellweger Spectrum Disorder: A Cross-Sectional Study Of Symptom Prevalence Using Input From Family Caregivers, Mousumi Bose, David D. Cuthbertson, Marsha A. Fraser, Jean Baptiste Roullet, K. Michael Gibson, Dana R. Schules, Kelly M. Gawron, Melissa B. Gamble, Kathryn M. Sacra, Melisa J. Lopez, William B. Rizzo

Department of Nutrition and Food Studies Scholarship and Creative Works

Zellweger spectrum disorders (ZSD) are rare, debilitating genetic diseases of peroxisome biogenesis that affect multiple organ systems and present with broad clinical heterogeneity. Although many case studies have characterized the multitude of signs and symptoms associated with ZSD, there are few reports on the prevalence of symptoms to help inform the development of meaningful endpoints for future clinical trials in ZSD. In the present study, we used an online survey tool completed by family caregivers to study the occurrence, frequency and severity of symptoms in individuals diagnosed with ZSD. Responses from caregivers representing 54 living and 25 deceased individuals with …

Availability And Consumption Of Vitamin A Foods Among Southern Ethiopian And Zambian Primary Students, Trang Vuong

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Understand vitamin A food availability in open-air markets (OAM’s), and consumption of those foods by primary school children in southern Ethiopia/Zambia.

Methods: Conducted inventories of all consumable/potable items and interviewed 6-7th grade students about consumption of items with vitamin A.

Results: Students consumed most of the 14 vitamin A foods/items sold in OAM’s. Zambian students ate more liver, pumpkin, squash, watermelon, and wild fruits, while Ethiopian students almost never consumed squash, watermelon or wild fruits.

Conclusions: The availability of Vitamin A foods in Ethiopian and Zambian OAMs are varied; however, Zambian children reportedly eat more vitamin A foods. Nutrition …

The Role Of Prenatal Food Insecurity On Breastfeeding Behaviors: Findings From The United States Pregnancy Risk Assessment Monitoring System, Lauren Dinour, Elizabeth I. Rivera Rodas, Ndidiamaka Amutah-Onukagha, Laurén A. Doamekpor

Department of Nutrition and Food Studies Scholarship and Creative Works

Background

In addition to its health and nutritional benefits, breastfeeding can save low-income, food insecure mothers the cost of infant formula so that money can be spent on food and other necessities. Yet breastfeeding may exacerbate food insecurity by negatively affecting maternal employment. The relationship between food insecurity and breastfeeding has been explored previously, with varying results. The purpose of this study was to determine the relationship between prenatal food insecurity and breastfeeding initiation and early cessation (< 10 weeks) among U.S. mothers.

Methods

Data were pooled from 2012 to 2013 (Phase 7) of the Pregnancy Risk Assessment Monitoring System, a population-based cross-sectional survey of …

Effects Of Daily 24-Gram Doses Of Rice Or Whey Protein On Resistance Training Adaptations In Trained Males, Jessica M. Moon, Kayla M. Ratliff, Julia C. Blumkaitis, Patrick S. Harty, Hannah A. Zabriskie, Richard A. Stecker, Brad S. Currier, Andrew R. Jagim, Ralf Jäger, Martin Purpura, Chad M. Kerksick

Faculty Scholarship

Large (48-g), isonitrogenous doses of rice and whey protein have previously been shown to stimulate similar adaptations to resistance training, but the impact of consuming smaller doses has yet to be compared. We evaluated the ability of 24-g doses of rice or whey protein concentrate to augment adaptations following 8 weeks of resistance training.

A Theacrine-Based Supplement Increases Cellular Nad+ Levels And Affects Biomarkers Related To Sirtuin Activity In C2c12 Muscle Cells In Vitro, Petey W. Mumford, Shelby C. Osburn, Carlton D. Fox, Joshua S. Godwin, Michael D. Roberts

Faculty Scholarship

There is evidence in rodents to suggest that theacrine-based supplements modulate tissue sirtuin activity as well as other biological processes associated with aging. Herein, we examined if a theacrine-based supplement (termed NAD3) altered sirtuin activity in vitro while also affecting markers of mitochondrial biogenesis. The murine C2C12 myoblast cell line was used for experimentation. Following 7 days of differentiation, myotubes were treated with 0.45 mg/mL of NAD3 (containing ~2 mM theacrine) for 3 and 24 h (n = 6 treatment wells per time point). Relative to control (CTL)-treated cells, NAD3 treatments increased (p < 0.05) Sirt1 mRNA levels at 3 h, as well as global sirtuin activity at 3 and 24 h. Follow-up experiments comparing 24 h NAD3 or CTL treatments indicated that NAD3 increased nicotinamide phosphoribosyltransferase (NAMPT) and SIRT1 protein levels (p < 0.05). Cellular nicotinamide adenine dinucleotide (NAD+) levels were also elevated nearly two-fold after 24 h of NAD3 versus CTL treatments (p < 0.001). Markers of mitochondrial biogenesis were minimally affected. Although these data are limited to select biomarkers in vitro, these preliminary findings suggest that a theacrine-based supplement can modulate select biomarkers related to NAD+ biogenesis and sirtuin activity. However, these changes did not drive increases in mitochondrial biogenesis. While promising, these data are limited to a rodent cell line and human muscle biopsy studies are needed to validate and elucidate the significance of these findings.

Dietary Regulation Of Successful Aging, Aubree L. Hawley

Graduate Theses and Dissertations

The current growth of the older population is unprecedented in U.S. history. Chronic disease and functional limitation commonly develop prior to old age, leading to prolonged physical disability and decreased well-being. The development of chronic disease and loss of independence is associated with lean body mass (LBM) loss and fat mass gain beginning in middle age. Therefore, it is important to identify modifiable factors to mitigate deleterious shifts in body composition to promote successful aging (SA). The concept of SA is associated with longevity, the absence of disease and disability, and subjective components of well-being, however, an operational definition has …

The Effect Of Epa And Dha On Skeletal Muscle Physiology And Energy Balance, Saeed Jebor Ghnaimawi

Graduate Theses and Dissertations

Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) supplementation commonly suggested during pregnancy confers many health benefits on offspring and more recently improves fetal BAT development and induces myoblast trans-differentiation into adiopocytes through activating PPARs expression. Embryonic myoblast is a highly flexible cell showing great capacity to change its phenotype into adipocyte in response to EPA and DHA supplementation in many in vitro models. However, a little is known about the identity of derived adipocytes, whether, they change into brown or white adipocyte, and in vivo evidence is still missing. Given that the myogeneis process is initiated at the mid of …

Ionic Mechanism Of Lysosomal Function And Cell Metabolism, Jian Xiong

Dissertations and Theses (Open Access)

Two Pore Channels (TPCs) are endolysosomal ion channels that are permeable to sodium and calcium. Defects in TPCs have been implicated to impair vesicle trafficking, autophagy and cell metabolism control; however, the detailed mechanism remains largely unknown. In this study, I show that TPCs are critical for appropriate cargo delivery to the lysosomes and deletion of either TPC1 or TPC2 leads to delayed clearance of autophagosomes, resulting in enlarged lysosomes and accumulated contents inside the lysosomes. Cells with both TPC deleted also exhibit 50% reduction in lysosomal amino acids under normal culture conditions, leading to reduced homeostatic mTORC1 activation.

Glutamine …