Nutrition Commons^™

Zika Virus Infection Induces Endoplasmic Reticulum Stress And Apoptosis In Placental Trophoblasts, Philma Glora Muthuraj, Prakash K. Sahoo, Madison Kraus, Taylor Bruett, Arun S. Annamalai, Aryamav Pattnaik, Siddappa N. Byrareddy, Sathish Kumar Natarajan

Department of Nutrition and Health Sciences: Faculty Publications

Zika virus (ZIKV) infection to a pregnant woman can be vertically transmitted to the fetus via the placenta leading to Congenital Zika syndrome. This is characterized by microcephaly, retinal defects, and intrauterine growth retardation. ZIKV induces placental trophoblast apoptosis leading to severe abnormalities in the growth and development of the fetus. However, the molecular mechanism behind ZIKV-induced apoptosis in placental trophoblasts remains unclear. We hypothesize that ZIKV infection induces endoplasmic reticulum (ER) stress in the trophoblasts, and sustained ER stress results in apoptosis. HTR-8 (HTR-8/SVneo), a human normal immortalized trophoblast cell and human choriocarcinoma-derived cell lines (JEG-3 and JAR) were …

Exercise Shifts Hypothetical Food Choices Toward Greater Amounts And More Immediate Consumption, Karsten Koehler, Safiya E. Beckford, Elise Thayer, Alexandra R. Martin, Julie B. Boron, Jeffrey R. Stevens

Department of Nutrition and Health Sciences: Faculty Publications

Although exercise modulates appetite regulation and food intake, it remains poorly understood how exercise impacts decision-making about food. The purpose of the present study was to assess the impact of an acute exercise bout on hypothetical choices related to the amount and timing of food intake. Forty-one healthy participants (22.0 ± 2.6 years; 23.7 ± 2.5 kg/m² , 56% female) completed 45 min of aerobic exercise and a resting control condition in randomized order. Food amount preferences and intertemporal food preferences (preference for immediate vs. delayed consumption) were assessed using electronic questionnaires with visual food cues. Compared to rest, …

Applications Of The Critical Power Model To Dynamic Constant External Resistance Exercise: A Brief Review Of The Critical Load Test, Haley C. Bergstrom, Taylor K. Dinyer, Pasquale J. Succi, Caleb C. Voskuil, Terry J. Housh

Department of Nutrition and Health Sciences: Faculty Publications

The study and application of the critical power (CP) concept has spanned many decades. The CP test provides estimates of two distinct parameters, CP and W0 , that describe aerobic and anaerobic metabolic capacities, respectively. Various mathematical models have been used to estimate the CP and W0 parameters across exercise modalities. Recently, the CP model has been applied to dynamic constant external resistance (DCER) exercises. The same hyperbolic relationship that has been established across various continuous, whole-body, dynamic movements has also been demonstrated for upper-, lower-, and whole-body DCER exercises. The asymptote of the load versus repetition relationship is defined …

Buy Fresh, Buy Local: Nebraska Working Together For Local Food, Margaret Milligan

Cornhusker Economics

Direct market farms in Nebraska are made up of people passionate about raising good food for their fellow Nebraskans. They grow vegetables, fruits, meat, grains, and value-added products to sell directly to consumers in their communities.

During the pandemic, these small farms have experienced restaurant sales vanishing, farmers’ market attendance de-creasing, and slots filling up at the small meat processors where they take their livestock. At the same time, there has been a renewed interest from consumers seeking reliable, transparent food produced close to home. It’s been a volatile year, and it has required quick pivoting, group coordination and action …

Excessive Intake Of Iodine And Low Prevalence Of Goiter In School Age Children Five Years After Implementation Of National Salt Iodization In Shebedino Woreda, Southern Ethiopia, Elilta Elias, Workneh Tsegaya, Barbara J. Stoecker, Tafere Gebreegziabher Belay

All Faculty Scholarship for the College of the Sciences

Background

Iodine is a trace element required for the synthesis of thyroid hormones. The multiple effects of iodine deficiency on human health are called iodine deficiency disorders (IDDs). IDDs have been common nutritional problems in Ethiopia. In 2012, Ethiopia launched a national salt iodization program to address IDDs. The objective of this study was to assess the effects of this program after 5 years by measuring urinary iodine concentration (UIC) and prevalence of goiter in school age children as well as household salt iodine concentration (SIC).

Methods

A school-based cross-sectional design was employed. After ethical approval, 408 children from eight …

Parenteral Fish-Oil Containing Lipid Emulsions Limit Initial Lipopolysaccharide-Induced Host Immune Responses In Preterm Pigs, William Yakah, David Ramiro-Cortijo, Pratibha Singh, Joanne Brown, Barbara Stoll, Madhulika Kulkarni, Berthe C Oosterloo, Doug Burrin, Krishna Rao Maddipati, Raina N Fichorova, Steven D Freedman, Camilia R Martin

Children’s Nutrition Research Center Staff Publications

Multicomponent lipid emulsions are available for critical care of preterm infants. We sought to determine the impact of different lipid emulsions on early priming of the host and its response to an acute stimulus. Pigs delivered 7d preterm (n = 59) were randomized to receive different lipid emulsions for 11 days: 100% soybean oil (SO), mixed oil emulsion (SO, medium chain olive oil and fish oil) including 15% fish oil (MO15), or 100% fish oil (FO100). On day 11, pigs received an 8-h continuous intravenous infusion of either lipopolysaccharide (LPS—lyophilized Escherichia coli) or saline. Plasma was collected for …

Role Of Lab In Silage Fermentation: Effect On Nutritional Quality And Organic Acid Production—An Overview, Da Hye Kim, Kyung Dong Lee, Ki Choon Choi

Center for Research on Environmental Disease Faculty Publications

Lactic acid bacteria (LAB) inocula play a key role in the preservation and fermentation of forage crops within inoculated silages. LAB is a significant group of the bacterial community as they successfully reduce pH, inhibit the survival of undesirable microorganisms and control nutrient loss in fermented silage. Ensiled plants and metabolites such as simple plant carbohydrates have been utilized by LAB (homo-fermentative and hetero-fermentative LAB) to initiate the production of organic acids including lactic and acetic acids. LAB as a biological silage additive provides stable feed value and secondary metabolic products during rapid anaerobic primary silage fermentation. They are able …

Agrp Neurons Trigger Long-Term Potentiation And Facilitate Food Seeking, Chunmei Wang, Wenjun Zhou, Yang He, Tiffany Yang, Pingwen Xu, Yongjie Yang, Xing Cai, Julia Wang, Hesong Liu, Meng Yu, Chen Liang, Tingting Yang, Hailan Liu, Makoto Fukuda, Qingchun Tong, Qi Wu, Zheng Sun, Yanlin He, Yong Xu

Children’s Nutrition Research Center Staff Publications

Sufficient feeding is essential for animals' survival, which requires a cognitive capability to facilitate food seeking, but the neurobiological processes regulating food seeking are not fully understood. Here we show that stimulation of agouti-related peptide-expressing (AgRP) neurons triggers a long-term depression (LTD) of spontaneous excitatory post-synaptic current (sEPSC) in adjacent pro-opiomelanocortin (POMC) neurons and in most of their distant synaptic targets, including neurons in the paraventricular nucleus of the thalamus (PVT). The AgRP-induced sEPCS LTD can be enhanced by fasting but blunted by satiety signals, e.g. leptin and insulin. Mice subjected to food-seeking tasks develop similar neural plasticity in AgRP-innervated …

Reducing The Obesity Epidemic Globally, Kimberli Pepper

Global Sustainable Development Projects

The consumption of high fructose corn syrup (HFCS) has caused a global obesity epidemic that has several health implications such as type two diabetes, fatty liver disease, kidney failure, oxidative stress, insulin resistance, multiple types of cancer, and pathogenesis of cardiometabolic diseases (Johnson et al., 2013; Malik and Hu, 2015; Romieu et al., 2017; Softic et al., 2016). The prevalence of obesity in the United States was evaluated by the Center for Disease Control (CDC) and reported that USA was at 39.8 percent, which is a significant risk factor for the development of type two diabetes mellitus (T2DM) (Mejia and …

A Narrative Review Of Grocery Store Interventions On Improving Healthy Food Purchases, Kylie Serie

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

Objective: The objective of the literature review was to understand and review current research in the area of grocery store interventions to improve purchasing of healthy foods.
Methods: PubMed and web-based searches were done for original research literature that looked at supermarket and grocery store interventions promoting healthy food choices. The literature could include qualitative and quantitative data. Keywords that were used include: “grocery store,” “interventions,” “healthy eating,” “supermarket,” “healthy foods,” “store intervention,” “food retail intervention,” “convenience store.”
Results: The review showed that there are studies on supermarket interventions. Interventions that showed positive outcomes were those that had direct …

Evaluating The Nutritional Adequacy Of Peruvian-American Children, Delainey Dietz

Honors Undergraduate Theses

As people move and integrate cultures, nutritional trends may change from those of their native country to those of their new country. With today's increasing global immigration, studies have only scratched the surface of the impact of acculturation on children's health and nutrition. Specifically, the Peruvian-American diet is one that has garnered minimal research. The purpose of this study is to evaluate the common foods and drinks that Peruvian-American children consume, assess the children's physical health, and discuss the possible causative factors of any diet trends. The population sampled is children under 18 years living in the United States whose …

Household Water Filter Distribution Reduces Diarrhea In Liberia, Sadie Kornoelje, Blerta Lika, Nathan Wang, Stacy L. De Ruiter, Randall Pruim

Summer Research

Liberian Background

• Liberia has an estimated 4.82 million citizens
• 84% have access to water
• 74% have access to drinking water within 30-minute walking radius

Research on Diarrheal Rates

• 6th leading cause of death for children under the age of 5
• In 2016, 6 out of every 1000 children in Liberia died of diarrhea
• Associated with malnutrition and stunted growth
• Hypothesis: Access to filters at the household level will be positively associated with reductions in diarrheal disease

Improvisation-Based Curriculum For Nutrition And Dietetics Undergraduate Students: An Examination In Alternative Education Methods, Megan Farris

Graduate Research Theses & Dissertations

Introduction: Medical improvisation is the use of theatrical-based games to develop interpersonal communication skills (ICS), including those applicable to telehealth communication, among health care professionals.

Purpose: The purpose of this study was to determine if implementing a medical improvisation-based workshop via a virtual classroom within an upper-level undergraduate nutrition and dietetics counseling course improved students’ self-assessed perceived capability of the following characteristics required as ICS for telehealth communication: becoming a better listener, becoming more observant of nonverbal communication, responding in the moment, increasing self-confidence in presenting, and becoming a better team member/collaborator. This study also considered the feasibility of using …

Inulin-Containing Fructo-Oligosaccharides And Anxiety Scores In College Students, Spencer Herkes

Graduate Research Theses & Dissertations

The purpose of this study was to determine the effects of inulin, in the form of fructo-oligosaccharides (FOS), on anxiety symptoms in college students. With a prevalence of 40 million adults in the United States, or 18.1% of the population, anxiety is the most common mental illness in the United States. Previous studies have viewed gut microbiota and its potential link to anxiety both in humans and in mice. However, no previous studies viewed college students. Thirteen subjects were assigned to receive either 4.9 g per day of inulin as a treatment (TX) or no supplement as a control (CON) …

Health And Nutrition Status Of Hemodialysis Patients During Ramadan In Saudi Arabia., Bayan Mansour Tashkandi

Wayne State University Dissertations

During Ramadan R month, Muslims abstain from eating, drinking, and medication from sunrise to sunset, and this causes some changes in their lifestyle and often eating habits (quantity and quality). These changes could lead to affect their health and nutritional status. Among Hemodialysis (HD) patients, malnutrition is common, and it is associated with mortality. Some HD patients opt to fast R which could have an impact on their nutritional and health status. Thus, the primary objective of this study was to document nutritional changes before, during, and after Ramadan on biochemical and health parameters in HD patients. A prospective cohort …

Instructions For Authors, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Characterization Of Clostridium Cochlearium As A Potential Probiotic For Obesity Management, Paba Edirisuriya

Wayne State University Dissertations

ABSTRACTCHARACTERIZATION OF CLOSTRIDIUM COCHLEARIUM AS A POTENTIAL PROBIOTIC FOR OBESITY MANAGEMENT

ByPABA EDIRISURIYA MAY 2021 Advisor: Dr. Kequan Zhou Major: Nutrition and food science Degree: Doctor of Philosophy Emerging evidence indicates that manipulation of gut microflora is a potential therapeutic approach for managing obesity. Probiotic effects on host weight reduction have repeatedly been revealed through previous studies. Clostridium cochlearium is a butyrate-producing, spore-forming bacteria that have been reported to present in the mammalian gut. Our simulated Invitro digestion model revealed that C. cochlearium could survive in the unfavorable conditions of the human gastrointestinal tract, including low pH (pH2), high bile …

Impact Of Acquiring Childhood Cooking Skills On Adults’ Dietary Behaviors, Suzanne Check

Graduate Research Theses & Dissertations

The ability to cook and prepare foods from fresh ingredients is a necessary life skill to improve overall diet quality and to prevent or reduce the risk of chronic diseases. Limited research exists on the appropriate time to develop these skills to have a long-term impact on diet quality and health. The primary objective of this study was to determine whether the age of learning cooking skills promotes higher cooking confidence and diet quality during adulthood. In addition, the study investigated the impact of learning cooking skills from various sources on diet quality and cooking confidence in adulthood. A cross-sectional …

Reduced Mitochondrial Dna And Oxphos Protein Content In Skeletal Muscle Of Children With Cerebral Palsy, Ferdinand Von Walden, Ivan J. Vechetti Jr, Davis Englund, Vandre C. Figueiredo, Rodrigo Fernandez-Gonzalo, Kevin Murach, Jessica Pingel, John J. Mccarthy, Per Stal, Eva Ponten

Department of Nutrition and Health Sciences: Faculty Publications

AIM To provide a detailed gene and protein expression analysis related to mitochondrial biogenesis and assess mitochondrial content in skeletal muscle of children with cerebral palsy (CP). METHOD Biceps brachii muscle samples were collected from 19 children with CP (mean [SD] age 15y 4mo [2y 6mo], range 9–18y, 16 males, three females) and 10 typically developing comparison children (mean [SD] age 15y [4y], range 7–21y, eight males, two females). Gene expression (quantitative reverse transcription polymerase chain reaction [PCR]), mitochondrial DNA (mtDNA) to genomic DNA ratio (quantitative PCR), and protein abundance (western blotting) were analyzed. Microarray data sets (CP/aging/bed rest) were …

Factors Associated With Lifestyle Modification For Type 2 Diabetes Self-Management And Prevention, Leigh Anne Koonmen

Theses and Dissertations--Nursing

Diabetes is the seventh leading cause of death in the United States, affecting roughly 13% of U.S. adults aged 18 years or older. Type 2 diabetes accounts for 90-95% of all diabetes cases and is characterized by the progressive development of insulin resistance leading to sustained elevated blood glucose levels. Management of type 2 diabetes includes risk-reduction strategies and continuous medical care to prevent the development of complications.

Lifestyle is a major contributing factor to morbidity and mortality rates in the United States. Preventative health behaviors, such as engaging in physical activity, maintaining a healthy weight, and following a healthy …