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Identification Of Anti-Inflammatory Vesicle-Like Nanoparticles In Honey, Xingyi Chen, Boalong Liu, Xingzhi Li, Thuy T. An, You Zhou, Gang Li, Judy Wu-Smart, Sophie Alvarez, Michael J. Naldrett, James Eudy, Gregory Kubik, Richard A. Wilson, Stephen D. Kachman, Juan Cui, Jiujiu Yu 2021 University of Nebraska - Lincoln

Identification Of Anti-Inflammatory Vesicle-Like Nanoparticles In Honey, Xingyi Chen, Boalong Liu, Xingzhi Li, Thuy T. An, You Zhou, Gang Li, Judy Wu-Smart, Sophie Alvarez, Michael J. Naldrett, James Eudy, Gregory Kubik, Richard A. Wilson, Stephen D. Kachman, Juan Cui, Jiujiu Yu

Department of Nutrition and Health Sciences: Faculty Publications

Honey has been used as a nutrient, an ointment, and a medicine worldwide for many centuries. Modern research has demonstrated that honey has many medicinal properties, reflected in its anti-microbial, anti-oxidant, and anti-inflammatory bioactivities. Honey is composed of sugars, water and a myriad of minor components, including minerals, vitamins, proteins and polyphenols. Here, we report a new bioactive component‒vesicle-like nanoparticles‒in honey (H-VLNs). These HVLNs are membrane-bound nano-scale particles that contain lipids, proteins and small-sized RNAs. The presence of plant-originated plasma transmembrane proteins and plasma membrane-associated proteins suggests the potential vesicle-like nature of these particles. H-VLNs impede the formation and activation …


Zika Virus Infection Induces Endoplasmic Reticulum Stress And Apoptosis In Placental Trophoblasts, Philma Glora Muthuraj, Prakash K. Sahoo, Madison Kraus, Taylor Bruett, Arun S. Annamalai, Aryamav Pattnaik, Siddappa N. Byrareddy, Sathish Kumar Natarajan 2021 University of Nebraska - Lincoln

Zika Virus Infection Induces Endoplasmic Reticulum Stress And Apoptosis In Placental Trophoblasts, Philma Glora Muthuraj, Prakash K. Sahoo, Madison Kraus, Taylor Bruett, Arun S. Annamalai, Aryamav Pattnaik, Siddappa N. Byrareddy, Sathish Kumar Natarajan

Department of Nutrition and Health Sciences: Faculty Publications

Zika virus (ZIKV) infection to a pregnant woman can be vertically transmitted to the fetus via the placenta leading to Congenital Zika syndrome. This is characterized by microcephaly, retinal defects, and intrauterine growth retardation. ZIKV induces placental trophoblast apoptosis leading to severe abnormalities in the growth and development of the fetus. However, the molecular mechanism behind ZIKV-induced apoptosis in placental trophoblasts remains unclear. We hypothesize that ZIKV infection induces endoplasmic reticulum (ER) stress in the trophoblasts, and sustained ER stress results in apoptosis. HTR-8 (HTR-8/SVneo), a human normal immortalized trophoblast cell and human choriocarcinoma-derived cell lines (JEG-3 and JAR) were …


Exercise Shifts Hypothetical Food Choices Toward Greater Amounts And More Immediate Consumption, Karsten Koehler, Safiya E. Beckford, Elise Thayer, Alexandra R. Martin, Julie B. Boron, Jeffrey R. Stevens 2021 Technical University of Munich

Exercise Shifts Hypothetical Food Choices Toward Greater Amounts And More Immediate Consumption, Karsten Koehler, Safiya E. Beckford, Elise Thayer, Alexandra R. Martin, Julie B. Boron, Jeffrey R. Stevens

Department of Nutrition and Health Sciences: Faculty Publications

Although exercise modulates appetite regulation and food intake, it remains poorly understood how exercise impacts decision-making about food. The purpose of the present study was to assess the impact of an acute exercise bout on hypothetical choices related to the amount and timing of food intake. Forty-one healthy participants (22.0 ± 2.6 years; 23.7 ± 2.5 kg/m2 , 56% female) completed 45 min of aerobic exercise and a resting control condition in randomized order. Food amount preferences and intertemporal food preferences (preference for immediate vs. delayed consumption) were assessed using electronic questionnaires with visual food cues. Compared to rest, …


Applications Of The Critical Power Model To Dynamic Constant External Resistance Exercise: A Brief Review Of The Critical Load Test, Haley C. Bergstrom, Taylor K. Dinyer, Pasquale J. Succi, Caleb C. Voskuil, Terry J. Housh 2021 University of Kentucky

Applications Of The Critical Power Model To Dynamic Constant External Resistance Exercise: A Brief Review Of The Critical Load Test, Haley C. Bergstrom, Taylor K. Dinyer, Pasquale J. Succi, Caleb C. Voskuil, Terry J. Housh

Department of Nutrition and Health Sciences: Faculty Publications

The study and application of the critical power (CP) concept has spanned many decades. The CP test provides estimates of two distinct parameters, CP and W0 , that describe aerobic and anaerobic metabolic capacities, respectively. Various mathematical models have been used to estimate the CP and W0 parameters across exercise modalities. Recently, the CP model has been applied to dynamic constant external resistance (DCER) exercises. The same hyperbolic relationship that has been established across various continuous, whole-body, dynamic movements has also been demonstrated for upper-, lower-, and whole-body DCER exercises. The asymptote of the load versus repetition relationship is defined …


Reduced Mitochondrial Dna And Oxphos Protein Content In Skeletal Muscle Of Children With Cerebral Palsy, Ferdinand von Walden, Ivan J. Vechetti Jr, Davis Englund, Vandre C. Figueiredo, Rodrigo Fernandez-Gonzalo, Kevin Murach, Jessica Pingel, John J. McCarthy, Per Stal, Eva Ponten 2021 Karolinska Institute

Reduced Mitochondrial Dna And Oxphos Protein Content In Skeletal Muscle Of Children With Cerebral Palsy, Ferdinand Von Walden, Ivan J. Vechetti Jr, Davis Englund, Vandre C. Figueiredo, Rodrigo Fernandez-Gonzalo, Kevin Murach, Jessica Pingel, John J. Mccarthy, Per Stal, Eva Ponten

Department of Nutrition and Health Sciences: Faculty Publications

AIM To provide a detailed gene and protein expression analysis related to mitochondrial biogenesis and assess mitochondrial content in skeletal muscle of children with cerebral palsy (CP). METHOD Biceps brachii muscle samples were collected from 19 children with CP (mean [SD] age 15y 4mo [2y 6mo], range 9–18y, 16 males, three females) and 10 typically developing comparison children (mean [SD] age 15y [4y], range 7–21y, eight males, two females). Gene expression (quantitative reverse transcription polymerase chain reaction [PCR]), mitochondrial DNA (mtDNA) to genomic DNA ratio (quantitative PCR), and protein abundance (western blotting) were analyzed. Microarray data sets (CP/aging/bed rest) were …


Differential Effects Of Whole Red Raspberry Polyphenols And Their Gut Metabolite Urolithin A On Neuroinflammation In Bv-2 Microglia, Ashley Mulcahy Toney, Mahaa Albusharif, Duncan Works, Luke Polenz, Stacie Schlange, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung 2021 University of Nebraska - Lincoln

Differential Effects Of Whole Red Raspberry Polyphenols And Their Gut Metabolite Urolithin A On Neuroinflammation In Bv-2 Microglia, Ashley Mulcahy Toney, Mahaa Albusharif, Duncan Works, Luke Polenz, Stacie Schlange, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Whole red raspberry polyphenols (RRW), including ellagic acid, and their gut-derived metabolite, urolithin A (UroA), attenuate inflammation and confer health benefits. Although results from recent studies indicate that polyphenols and UroA also provide neuroprotective effects, these compounds differ in their bioavailability and may, therefore, have unique effects on limiting neuroinflammation. Accordingly, we aimed to compare the neuroprotective effects of RRW and UroA on BV-2 microglia under both 3 h and 12 and 24 h inflammatory conditions. In inflammation induced by lipopolysaccharide (LPS) and ATP stimulation after 3 h, RRW and UroA suppressed pro- inflammatory cytokine gene expression and regulated the …


Covid-19 Contagion Among Communities With Limited English Proficiency: Lesson From Volunteerism, Falah N. Rashoka M.S 2021 University of Nebraska - Lincoln

Covid-19 Contagion Among Communities With Limited English Proficiency: Lesson From Volunteerism, Falah N. Rashoka M.S

Department of Nutrition and Health Sciences: Faculty Publications

The COVID-19 affects all communities in the United States, but its impact differs from one community to another. Undoubtedly, the vulnerable populations are more impacted than others, especially refugees and immigrants. This study seeks to understand the impact of COVID-19 on marginalized communities and the need to communicate health-related information equally. A lesson learned from observation during an ongoing pandemic, including what I learned through my volunteer work between mid-March and August 2020. The study finds that neighbors with limited English Proficiency (LEP) and limited education could quickly transfer the COVID-19 virus to another neighbor with high income and well-educated. …


Essential Role Of Systemic Iron Mobilization And Redistribution For Adaptive Thermogenesis Through Hif2-Α/Hepcidin Axis, Jin-Seon Yook, Mikyoung You, Jiyoung Kim, University of Nebraska-Lincoln, Rong Fan, Bhanwar Lal Puniya, Tomáš Helikar, Sophie Vaulont, Jean-Christophe Deschemin, Meshail Oklar, Liwei Xie, Manik C. Ghosh, Tracey A. Rouault, Jaekwon Lee, Soonkyu Chung 2021 University of Massachusetts Amherst

Essential Role Of Systemic Iron Mobilization And Redistribution For Adaptive Thermogenesis Through Hif2-Α/Hepcidin Axis, Jin-Seon Yook, Mikyoung You, Jiyoung Kim, University Of Nebraska-Lincoln, Rong Fan, Bhanwar Lal Puniya, Tomáš Helikar, Sophie Vaulont, Jean-Christophe Deschemin, Meshail Oklar, Liwei Xie, Manik C. Ghosh, Tracey A. Rouault, Jaekwon Lee, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Iron is an essential biometal, but is toxic if it exists in excess. Therefore, iron content is tightly regulated at cellular and systemic levels to meet metabolic demands but to avoid toxicity. We have recently reported that adaptive thermogenesis, a critical metabolic pathway to maintain whole-body energy homeostasis, is an irondemanding process for rapid biogenesis of mitochondria. However, little information is available on iron mobilization from storage sites to thermogenic fat. This study aimed to determine the iron-regulatory network that underlies beige adipogenesis. We hypothesized that thermogenic stimulus initiates the signaling interplay between adipocyte iron demands and systemic iron liberation, …


Serving Refugees In A Pandemic: Insights From Yazidis In The Midwest, Falah N. Rashoka M.S, Megan S. Kelley, Marc A. Garcia 2021 University of Nebraska - Lincoln

Serving Refugees In A Pandemic: Insights From Yazidis In The Midwest, Falah N. Rashoka M.S, Megan S. Kelley, Marc A. Garcia

Department of Nutrition and Health Sciences: Faculty Publications

There is a critical need for research to examine factors that hinder or facilitate access to healthcare in the context of COVID-19. The coronavirus pandemic has exacerbated barriers to healthcare for marginalized communities globally, leaving many without access to needed health services. Resettled refugees, in particular, must grapple with added challenges to locating and obtaining culturally appropriate healthcare services.

Recent focus groups shed light on the experiences of Yazidi refugees in the U.S. Midwest during COVID-19. Yazidis are a historically persecuted religious and ethnic minority group from northern Iraq (Kizilhan, 2017). Many Yazidis migrated to the U.S. on Special Immigrant …


The Effects Of Phosphocreatine Disodium Salts Plus Blueberry Extract Supplementation On Muscular Strength, Power, And Endurance, John Paul V. Anders, Tyler J. Neltner, Robert W. Smith, Joshua L. Keller, Terry J. Housh, F Joseph Daugherty, Michael S. Tempesta, Alekha K. Dash, Daniel J. Munt, Richard J. Schmidt, Glen O. Johnson 2021 University of Nebraska - Lincoln

The Effects Of Phosphocreatine Disodium Salts Plus Blueberry Extract Supplementation On Muscular Strength, Power, And Endurance, John Paul V. Anders, Tyler J. Neltner, Robert W. Smith, Joshua L. Keller, Terry J. Housh, F Joseph Daugherty, Michael S. Tempesta, Alekha K. Dash, Daniel J. Munt, Richard J. Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Background: Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance. Furthermore, while polyphenols have antioxidant and anti-inflammatory properties, little is known regarding the influence of polyphenol supplementation on muscular strength, power, and endurance. Thus, the purpose of the present study was to compare the effects of 28 days of supplementation with phosphocreatine disodium salts plus blueberry extract (PCDSB), creatine monohydrate (CM), and placebo on measures of muscular strength, power, and endurance.

Methods: Thirty-three men were randomly assigned to consume either PCDSB, CM, …


Parents' Attitudes And Beliefs Towards Dietary Behaviors Of Children With Autism Aged 5-13 Years, Subashree Narayanan 2021 University of North Florida

Parents' Attitudes And Beliefs Towards Dietary Behaviors Of Children With Autism Aged 5-13 Years, Subashree Narayanan

UNF Graduate Theses and Dissertations

Autism is a neurodevelopmental disability that may affect nutritional management of children with autism. Parent’s attitudes and their behavior towards healthy eating reflects on the child’s eating habits and thus, their nutritional health. This study aimed to describe the diet quality of children with autism using the Healthy Eating Index (HEI) scores. It also aimed to assess the relationship between parent’s perceived barriers and self-efficacy and children’s dietary behavior and dietary intake (age 5-13 years). The relationship was assessed using 2 questionnaires, Nutrition and Health Awareness and BAMBI questionnaire for parent’s attitudes and beliefs and dietary behavior, respectively. Dietary intake …


Osteoporosis Prevention Is Linked To Education, Childhood Meals And Milk Consumption In Young Adult Females, Karen E. From 2021 University of North Florida

Osteoporosis Prevention Is Linked To Education, Childhood Meals And Milk Consumption In Young Adult Females, Karen E. From

UNF Graduate Theses and Dissertations

The three aims of the study investigated the females’ age 18-25 perception, knowledge, and health beliefs, barriers and strategies to overcoming barriers to prevent osteoporosis. The mixed method explanatory design of research was implemented. Phase one used a survey to gather demographic data, past and current behaviors, the completion of the Osteoporosis Health Behavior Scale (OHBS) questionnaire, and Short Calcium Intake List (SCaIL). Four hundred forty-nine quality survey responses were obtained. The second phase, the focus group (n=23), discussed questions designed to answer the three aims of the study. Results- Our analysis showed 90% of our 447 survey participants did …


A Review Of The Effects Of Dietary Restriction, Dehydration, And Caffeine Withdrawal On Cognition: Implications For A Disabled Submarine Scenario, Sarah Chabal 2020 Naval Submarine Medical Research Laboratory

A Review Of The Effects Of Dietary Restriction, Dehydration, And Caffeine Withdrawal On Cognition: Implications For A Disabled Submarine Scenario, Sarah Chabal

Journal of Human Performance in Extreme Environments

In the event that submariners become trapped aboard a disabled submarine (DISSUB), they must perform a multitude of cognitively demanding tasks in order to maximize their likelihood of survival. During this time, submariners will also be forced to endure poor living conditions, including drastic changes to their nutrition. These nutritional changes have the potential to impair submariners’ cognitive functioning and affect operational performance, which could jeopardize survival; however, the effects of DISSUB nutrition on cognitive performance are not well understood. This review first describes the unique nutritional conditions that submariners will experience in a DISSUB scenario, including the change to …


Brain Α-Tocopherol Concentration Is Inversely Associated With Neurofibrillary Tangle Counts In Brain Regions Affected In Earlier Braak Stages: A Cross-Sectional Finding In The Oldest Old, J. Tanprasertsuk, T.M. Scott, M.A. Johnson, L.W. Poon, P.T. Nelson, A. Davey, J.L. Woodard, R. Vishwanathan, A.K. Barbey, K. Barger, X.-D. Wang, E.J. Johnson 2020 Tufts University

Brain Α-Tocopherol Concentration Is Inversely Associated With Neurofibrillary Tangle Counts In Brain Regions Affected In Earlier Braak Stages: A Cross-Sectional Finding In The Oldest Old, J. Tanprasertsuk, T.M. Scott, M.A. Johnson, L.W. Poon, P.T. Nelson, A. Davey, J.L. Woodard, R. Vishwanathan, A.K. Barbey, K. Barger, X.-D. Wang, E.J. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Objectives: Higher vitamin E status has been associated with lower risk of Alzheimer’s disease (AD). However, evidence of the association of vitamin E concentration in neural tissue with AD pathologies is limited. Design: The cross-sectional relationship between the human brain concentrations of α- and γ-tocopherol and the severity of AD pathologies – neurofibrillary tangle (NFT) and neuritic plaque (NP) – was investigated. Setting & Participants: Brains from 43 centenarians (≥ 98 years at death) enrolled in the Phase III of the Georgia Centenarian Study were collected at autopsy. Measurements: Brain α- and γ-tocopherol concentrations (previously reported) …


Factors Associated With Minimum Dietary Diversity Among Breastfed Children Aged 6-23 Months In Indonesia (Analysis Of Indonesia Dhs 2017), Aniza Rizky Aprilya Sirait, Endang L. Achadi 2020 Undergraduate Student of Public Health Nutrition Department, Universitas Indonesia, Depok, West Java, Indonesia

Factors Associated With Minimum Dietary Diversity Among Breastfed Children Aged 6-23 Months In Indonesia (Analysis Of Indonesia Dhs 2017), Aniza Rizky Aprilya Sirait, Endang L. Achadi

Indonesian Journal of Public Health Nutrition (IJPHN)

Poor complementary feeding practices can lead to malnutrition in infants and young children. Minimum dietary diversity (MDD) is one of the determinants of children’s nutritional status and has been found to predict stunting. This study examined factors associated with MDD achievement among breastfed children aged 6-23 months based on Indonesia’s Demographic and Health Survey 2017. This study used chi-square and multiple logistic regression to analyze the data. Among 2,976 children only around 53% children met MDD recommendation. Multivariate analysis found that the diversity of diet is better among older children than younger children. Children aged 18-23 months have possibility of …


Associations Of Dietary Diversity And Other Factors With Prevalence Of Stunting Among Children Aged 6-35 Months, Kelvin Halim, Ratu Ayu Dewi Sartika, Trini Sudiarti, Primasti Nuryandari Putri, Nurul Dina Rahmawati 2020 Undergraduate Student of Public Health Nutrition Department, Universitas Indonesia, Depok, West Java, Indonesia

Associations Of Dietary Diversity And Other Factors With Prevalence Of Stunting Among Children Aged 6-35 Months, Kelvin Halim, Ratu Ayu Dewi Sartika, Trini Sudiarti, Primasti Nuryandari Putri, Nurul Dina Rahmawati

Indonesian Journal of Public Health Nutrition (IJPHN)

Prevalence of stunting among under five children in Indonesia is still considered as a public health problem. Dietary diversity, one of the important assessments in infant and child feeding practice, is one of important determinants of stunting. This study is aimed to examine associations between dietary diversity with other factors with prevalence of stunting in Babakan Madang District, Bogor Regency in 2019. A cross-sectional design study was performed in this study during April-June in 2019. A total of 149 children’s height aged 6- 35 months was measured and defined based on WHO growth standards. Dietary diversity scores were collected from …


Hypercholesterolemia Differences Based On Body Fat Percentage In Diabetic Patients At Pasar Minggu Primary Health Care 2018, Asti Shafira, Ratu Ayu Dewi Sartika, Diah Mulyawati Utari 2020 Undergraduate Student of Public Health Nutrition Department, Universitas Indonesia, Depok, West Java, Indonesia

Hypercholesterolemia Differences Based On Body Fat Percentage In Diabetic Patients At Pasar Minggu Primary Health Care 2018, Asti Shafira, Ratu Ayu Dewi Sartika, Diah Mulyawati Utari

Indonesian Journal of Public Health Nutrition (IJPHN)

Hypercholesterolemia is the leading predictor of various cardiovascular disease (CVD) which is the leading cause of death in the world. This study aims to determine whether there are any differences the incidence of hypercholesterolemia based on factors related to it in people with diabetes mellitus at Pasar Minggu Primary Health Care in 2018. This study used a cross-sectional method with a sample size of 126 respondents using consecutive sampling. Research variables studied were incidence of hypercholesterolemia, sex, duration of diabetes mellitus, family history of diabetes mellitus, smoking habit, physical activity, stress level, body fat percentage and fat intake. The results …


The Differences Of Haemoglobin Changes Between Two Methods Of Ifa Supplementations Among Anemic Female Adolescent Students Of Miftahul Huda Al Azhar Langgensari Islamic Boarding School, West Java, Syabilila Indraswari, Endang L. Achadi 2020 Magister Program of Public Health Nutrition,Faculty of Public Health Universitas Indonesia

The Differences Of Haemoglobin Changes Between Two Methods Of Ifa Supplementations Among Anemic Female Adolescent Students Of Miftahul Huda Al Azhar Langgensari Islamic Boarding School, West Java, Syabilila Indraswari, Endang L. Achadi

Indonesian Journal of Public Health Nutrition (IJPHN)

Female adolescent students in boarding schools are vulnerable in having anemia due to packed schedule and limited animal source food. The aim of this research was to compare the differences of haemoglobin level after weekly Iron Folate Acid (IFA) tablet supplementation and weekly plus daily IFA tablet supplementation during menstruation for 8 week of intervention among anemic students. This study used quasi experimental non equivalent control group design. A total of 40 anemic respondents was selected in this study, 20 of them received a weekly IFA tablet supplementation (treatment 1 group), and the 20 other respondents received weekly plus daily …


Body Weight Prediction Model Using Mid Upper Arm Circumferences And Knee Height In Adult, Katherina Katherina, Trini Sudiarti 2020 Undergraduate Student of Public Health Nutrition Department, Universitas Indonesia, Depok, West Java, Indonesia

Body Weight Prediction Model Using Mid Upper Arm Circumferences And Knee Height In Adult, Katherina Katherina, Trini Sudiarti

Indonesian Journal of Public Health Nutrition (IJPHN)

Bodyweight is one of the most common anthropometric components to determin e a prescription for diet and drugs. However, this way proved to be a challenge for individuals who are unconscious and or have disabilities. The present study aims to derive a simple equation to estimate the bodyweight of adults in Jakarta by using a cross-sectional study on data taken with simple random sample method. Measurements of body weight (BW), the mid-upper arm circumference (MUAC), and the knee height (KH) were done in 164 adults in South Jakarta in May 2017. The resulting equation, which is derived by multi linear …


Encouraging Snap Shopper Participation At Utah Farmers Markets, A Best Practices Guide, Kelsey Hall, Alicia Meiners 2020 Utah State University

Encouraging Snap Shopper Participation At Utah Farmers Markets, A Best Practices Guide, Kelsey Hall, Alicia Meiners

All Current Publications

This guide’s steps were compiled during background research for advertising acceptance of SNAP benefits using Electronic Benefits Transfer (EBT) cards and the Double Up Food Bucks (Double Up) program offered at farmers markets throughout Utah. Information in this guide will expand marketing campaigns across Utah to promote farmers markets already accepting SNAP benefits, especially to minority and low-income populations. The information, however, may be generalized to other health/food programs and to populations with low incomes in other states.


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