Human and Clinical Nutrition Commons^™

Plum Supplementation And Lipid Profile: A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Moein Askarpour, Hamid Ghalandari, Leila Setayesh, Ehsan Ghaedi

Department of Nutrition and Health Sciences: Faculty Publications

Plums are abundant in bioactive compounds which have been associated with numerous health benefits. In the present study, we aimed at examining the impact of plum supplementation on lipid profile of individuals. Electronic bibliographical databases were searched for relevant randomised clinical trials. Articles meeting our eligibility criteria were included for data extraction and final analysis. Weighted mean difference (WMD) was estimated using a random-effect model. Of the total articles retrieved in the initial search, nine articles were found to be eligible to be included in the analysis. Our results show that plum supplementation significantly improves total cholesterols levels in the …

Microgreens Outreach In The Community - Applying A Novel Diet-Related Disease Prevention Tool, Jessica Nwabeke, Vibhuti Mishra, Rayna Marshall, Simone Udeh, Swaksha Rachuri, Ben Haslund-Gourley, Annette Gadegbeku

Tower Health Research Day

No abstract provided.

Webinars As A Tool For Increasing Awareness Of Diabetes Prevention And Management Programs, Cindy Jenkins, Carrie Durward, April Litchford, Catherine Hansen, Annette Prall, Caitlyn Jasumback

Outcomes and Impact Quarterly

Stakeholders sought to reduce the burden of preventable diabetes among adults in Utah via a “Food as Medicine” webinar series. The “Food as Medicine” webinar series sought to increase awareness of and enrollment in public diabetes programs. Evaluation results from the webinar series indicated an increase in awareness of diabetes programs and nutrition information needed to improve personal diabetes management.

The Go Wild With Whole Grains! School-Based Program: Positive Impacts Among Children, Joshua Bailey, Sara Van Offelen, Hyunjun Kim, Marla Reicks

Journal of Extension

Whole grain foods have been associated with health benefits, yet are underconsumed by youth compared to recommendations. This study evaluated impacts of a school-based curriculum among children in grades 3-5 to address barriers to intake (2018-2019) (n = 1,748). Surveys before and after the program indicated youth were more willing to try and better able to identify whole grain foods. Open-ended responses confirmed findings regarding increased ability to identify whole grain foods, increased preferences and perceptions of availability. Together, these impacts could increase the likelihood that youth can meet whole grain intake recommendations to improve diet quality and health.

Multi-Transcriptome Analysis Following An Acute Skeletal Muscle Growth Stimulus Yields Tools For Discerning Global And Myc Regulatory Networks, Kevin A. Murach, Zhengye Liu, Baptiste Jude, Vandre C. Figueiredo, Yuan Wen, Sabin Khadgi, Seongkyun Lim, Francielly Morena Da Silva, Nicholas P. Greene, Johanna T. Lanner, John J. Mccarthy, Ivan Jose Vechetti Jr, Ferdinand Von Walden

Department of Nutrition and Health Sciences: Faculty Publications

Myc is a powerful transcription factor implicated in epigenetic reprogramming, cellular plasticity, and rapid growth as well as tumorigenesis. Cancer in skeletal muscle is extremely rare despite marked and sustained Myc induction during loading-induced hypertrophy. Here, we investigated global, actively transcribed, stable, and myonucleus-specific transcriptomes following an acute hypertrophic stimulus in mouse plantaris. With these datasets, we define global and Myc-specific dynamics at the onset of mechanical overload-induced muscle fiber growth. Data collation across analyses reveals an under-appreciated role for the muscle fiber in extracellular matrix remodeling during adaptation, along with the contribution of mRNA stability to epigenetic-related transcript …

Can Body Mass Index Influence The Skin Temperature Of Adolescents? A Preliminary Study With The Use Of Infrared Thermography, Hamilton Henrique Teixeira Reis, Ciro José Brito, Alisson Gomes Da Silva, Manuel Sillero-Quintana, Victória Esther Teixeria Reis, Francisco Zacaron Werneck, Ismael Fernández-Cuevas, Matheus Santos Cerqueira, João Carlos Bouzas Marins

Department of Nutrition and Health Sciences: Faculty Publications

– Infrared thermography (IRT) has been used to assess skin temperature (Tsk), especially during the COVID-19 pandemic, as an important tool in medical screening not only of the general population, but also of young athletes. However, the subcutaneous adipose tissue can act as an insulator when the Tsk is assessed by IRT, modifying the normal Tsk data and leading to their misinterpretation. Considering that the body mass index (BMI) is an important predictor of obesity, the objective of this study was to verify if the Tsk measured by IRT is affected by the BMI in adolescents. A preliminary study was …

Dietary Approaches To The Treatment Of Autism Spectrum Disorders, Dhira Patel

Loma Linda University Electronic Theses, Dissertations & Projects

This chapter reviews the literature surrounding autism spectrum disorders (ASD) and their relation to gastrointestinal (GI), behavioral, neurological, and immunological functioning. Individuals with ASDs often have poor GI health, including bowel motility issues, autoimmune and/or other adverse responses to certain foods, and lack of necessary nutrient absorption. These issues may be caused or exacerbated by restrictive behavioral patterns (e.g., preference for sweet and salty foods and/or refusal of healthy foods). Those individuals with GI issues tend to demonstrate more behavioral deficits (e.g., irritability, agitation, hyperactivity) and also tend to have an imbalance in overall gut microbiome composition, thus corroborating several …

Body Image Perception And Its Association With Food Intake Among Undergraduate Students In Kuala Lumpur, Malaysia, Christie Loke Sin Mun, Roslee Rajikan, Hanis Mastura Yahya

Makara Journal of Health Research

Background: Body image dissatisfaction may lead to the practice of imbalanced diet to achieve the desired body weight. This study aimed to determine the association between body image perception and food intake among undergraduate students.

Methods: This cross-sectional study was conducted on the data of 155 students from three faculties located at National University of Malaysia, Kuala Lumpur. Assessments included demographic data, body mass index, Contour Drawing Rating Scale, and 3-day food records.

Results: The majority of the subjects were categorized as normal weight (64.5%), and the remaining were classified as underweight (26.5%), overweight (7.7%), and obese …

Continuous Glucose Monitoring Metrics For Earlier Identification Of Pre-Diabetes: Protocol For A Systematic Review And Meta-Analysis, Sara Gottfried, Laura Pontiggia, Andrew B. Newberg, Gregory Laynor, Daniel A. Monti

Institute of Emerging Health Professions Faculty Papers

Introduction: Glycaemic variability and other metrics are not well characterised in subjects without diabetes. More comprehensive sampling as obtained with continuous glucose monitoring (CGM) may improve diagnostic accuracy of the transition from health to pre-diabetes. Our goal is to investigate the glycaemic system as it shifts from health to pre-disease in adult patients without diabetes using CGM metrics. New insights may offer therapeutic promise for reversing dysglycaemia more successfully with dietary, nutritional and lifestyle change before progression occurs to pre-diabetes and diabetes.

Methods and analysis: This systematic review will include comprehensive searches of the PubMed, Scopus, Cochrane Library and ClinicalTrials.gov …

Metabolic Model Of Necrotizing Enterocolitis In The Premature Newborn Gut Resulting From Enteric Dysbiosis, Giorgio Casaburi, Jingjing Wei, Sufyan Kazi, Junlin Liu, Kewei Wang, Guo-Zhong Tao, Po-Yu Lin, James C. Y. Dunn, Bethany M. Henrick, Steven A. Frese, Karl G. Sylvester

Department of Nutrition and Health Sciences: Faculty Publications

Necrotizing enterocolitis (NEC) is a leading cause of premature newborn morbidity and mortality. The clinical features of NEC consistently include prematurity, gut dysbiosis and enteral inflammation, yet the pathogenesis remains obscure. Herein we combine metagenomics and targeted metabolomics, with functional in vivo and in vitro assessment, to define a novel molecular mechanism of NEC. One thousand six hundred and forty seven publicly available metagenomics datasets were analyzed (NEC = 245; healthy = 1,402) using artificial intelligence methodologies. Targeted metabolomic profiling was used to quantify the concentration of specified fecal metabolites at NEC onset (n = 8), during recovery ( …

Differential Progression Of Unhealthy Dietinduced Hepatocellular Carcinoma In Obese And Non-Obese Mice, Emma Hymel, Elizabeth Vlock, Kurt W. Fisher, Paraskevi A. Farazi

Department of Nutrition and Health Sciences: Faculty Publications

Background Non-alcoholic fatty liver disease (NAFLD) ranks first among liver diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops in lean individuals without metabolic syndrome. The prevalence of lean NAFLD is 7 percent in the U.S. and 25–30 percent in some Asian countries. NAFLD starts with excess liver fat accumulation (NAFL), progresses to nonalcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC). The pathogenesis of lean NASH-HCC and how it differs from obese NASH-HCC is not well understood.

Methods In this work, we generated a mouse model of lean and obese NASH-HCC using a …

Markers Of Fungal Translocation Are Elevated During Post-Acute Sequelae Of Sars-Cov-2 And Induce Nf-Κb Signaling, Leila B. Giron, Michael J. Peluso, Jianyi Ding, Grace Kenny, Netanel F. Zilberstein, Jane Koshy, Kai Ying Hong, Heather Rasmussen, Gregory E. Miller, Faraz Bishehsari, Robert A. Balk, James N. Moy, Rebecca Hoh, Scott Lu, Aaron R. Goldman, Hsin Yao Tang, Brandon C. Yee, Ahmed Chenna, John W. Winslow, Christos J. Petropoulos, J. Daniel Kelly, Haimanot Wasse, Jeffrey N. Martin, Qin Liu, Ali Keshavarzian, Alan Landay, Steven G. Deeks, Timothy J. Henrich, Mohamed Abdel-Mohsen

Department of Nutrition and Health Sciences: Faculty Publications

Long COVID, a type of post-acute sequelae of SARS-CoV-2 (PASC), has been associated with sustained elevated levels of immune activation and inflammation. However, the mechanisms that drive this inflammation remain unknown. Inflammation during acute coronavirus disease 2019 could be exacerbated by microbial translocation (from the gut and/or lung) to blood. Whether microbial translocation contributes to inflammation during PASC is unknown. We did not observe a significant elevation in plasma markers of bacterial translocation during PASC. However, we observed higher levels of fungal translocation - measured as β-glucan, a fungal cell wall polysaccharide - in the plasma of individuals experiencing PASC …

Active Consideration Of Health And Nutritional Quality Of Food Choices, Christopher R. Gustafson

Cornhusker Economics

Everyone can be positively influenced by effective interventions promoting healthier food choices. A handful of recent papers have documented positive impacts on dietary quality resulting from interventions that remind people to consider health through prompt messages or subtle priming in supermarkets and in controlled, online experiments. These studies have focused on the impact of reminders on nutritional quality rather than explaining how reminders work. An exception, Arslain, Gustafson, and Rose (2021), collected data on multiple elements of individuals' choice processes to trace the impact of reminders on decisions, showing that reminder messages led people to consider a healthier set of …

Qualifying Factors That Predict Weight Loss Success Within Diet Interventions, Jordan Losavio

LSU Master's Theses

Evidence-based diet strategies lead to weight loss for some, while for others, the same diet approach could result in trivial weight loss or even in weight gain. This prompts the underlying research question: what factors predict that a given diet strategy will be efficacious for some, but not for others? This research was a secondary analysis of clinical weight loss studies to determine which factors influence an individual’s weight loss success for three diet intervention strategies: low-carbohydrate, low-fat, and low-calorie. A combination of physiological, psychological, behavioral, and dietary factors was evaluated for each diet study. Multiple linear regression and logistic …

Sweet Taste Signaling: The Core Pathways And Regulatory Mechanisms, Sunil Kumar Sukumaran, Salin Raj Palayyan

Department of Nutrition and Health Sciences: Faculty Publications

Sweet taste, a proxy for sugar-derived calories, is an important driver of food intake, and animals have evolved robust molecular and cellular machinery for sweet taste signaling. The overconsumption of sugar-derived calories is a major driver of obesity and other metabolic diseases. A fine-grained appreciation of the dynamic regulation of sweet taste signaling mechanisms will be required for designing novel noncaloric sweeteners with better hedonic and metabolic profiles and improved consumer acceptance. Sweet taste receptor cells express at least two signaling pathways, one mediated by a heterodimeric G-protein coupled receptor encoded by taste 1 receptor members 2 and 3 (TAS1R2 …

Lisdexamfetamine Is An Effective Monotherapy For Moderate To Severe Binge Eating Disorder, Benjamin Young

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using

McElroy SL, Hudson J, Ferreira-Cornwell MC, Radewonuk J, Whitaker T, Gasior M. Lisdexamfetamine dimesylate for adults with moderate to severe binge eating disorder: Results of two pivotal phase 3 randomized controlled trials. Neuropsychopharmacology. 2016;41(5):1251-1260. https://doi.org/10.1038/npp.2015.275

for a young woman requesting a novel pharmacological intervention for a Binge Eating Disorder (BED).

Urinary Aflatoxin M1 Concentration And Its Determinants In School-Age Children In Southern Ethiopia, Tafere Gebreegziabher Belay, Melanie Dean, Elilta Elias, Workneh Tsegaye, Barbara J. Stoecker

All Faculty Scholarship for the College of Education and Professional Studies

Aflatoxins are mycotoxins that can contaminate grains, legumes, and oil seeds. These toxic compounds are an especially serious problem in tropical and sub-tropical climates. The objective of this study was to raise awareness of aflatoxin exposure among primary school children in Shebedino woreda, southern Ethiopia, by measuring urinary aflatoxin M1 (AFM1). The study employed a cross-sectional design and systematic random sampling of children from eight schools in the district. The mean ± SD age of the children was 9.0 ± 1.8 years. Most (84.6%) households were food insecure with 17.9% severely food insecure. Urinary AFM1 was detected in more than …

An Analysis Of Available European Food Composition Databases To Enable The Development Of A Technology-Based Dietary Assessment Tool, Hannah Al-Sehaim

ORBioM (Open Research BioSciences Meeting)

DIETARY DEAL is an EU-project led by MTU, tasked to develop an open-source dietary assessment tool (DAT) to harmonise collection and analysis of dietary data across Europe⁽¹⁾. A key component of all DATs is integrated food composition databases (FCD) containing energy and nutrient information (per 100g food) for translation of food intake data into nutrient estimates.

This preliminary research aimed to identify and quantify available FCD in European countries for inclusion in the new DAT.

Search terms such as [European Food Composition Databases], [Available Food Composition Databases in Europe] and [Recent European Food Composition Databases Published] were used …

The Effects Of Vitamin D Supplementation On Athletic Performance And Injury Prevention, Amani Adeeb Abushamma

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Vitamin D supplementation has numerous effects on athletic performance and plays a significant role in preventing an athlete’s risk of getting injuries. Vitamin D has an impact on numerous physiological functions such as: bone health, muscle function, inflammatory response, and immune function. An athlete’s bone and muscle health are essential for maximum performance and career success. A bone fracture due to vitamin D deficiency can delay an athlete’s training and ultimately inhibit obtaining a collegiate scholarship and/or contract. A cross sectional study found that more than half of athletic trainers did not view 25-hydroxyvitamin D(25[OH]) testing and vitamin D supplementation …

Food Insecurity And Health-Related Concerns Among Elementary Schoolteachers During The Covid-19 Pandemic, Fangyu Li, Nivedhitha Parthasarathy, Feng Zhang, Ru-Jye Chuang, Mallika Mathur, Mike Pomeroy, Jacqueline Noyola, Christine M Markham, Shreela V Sharma

Faculty, Staff and Student Publications

INTRODUCTION: US school systems underwent major upheaval, including closures, implementation of virtual and/or hybrid learning, and stringent infection mitigation protocols, during the initial phase of the COVID-19 pandemic. We aimed to examine the association between food insecurity and perceived health, perceived stress, and social determinants of health concerns among elementary schoolteachers serving predominantly low-income children during the COVID-19 pandemic.

METHODS: Brighter Bites, a nonprofit organization that weekly distributes fresh fruits and vegetables and nutrition education materials to more than 300 schools serving racial and ethnic minority populations with low income, conducts annual surveys of participating teachers to help determine subsequent …