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The Pre-Application Of Hydrocortisone Cream And Its Effect On Transdermal Drug Delivery By Phonophoresis, Patrick Thomas Webb 2012 Brigham Young University - Provo

The Pre-Application Of Hydrocortisone Cream And Its Effect On Transdermal Drug Delivery By Phonophoresis, Patrick Thomas Webb

Theses and Dissertations

Context: Transdermal delivery of hydrocortisone by phonophoresis is used for the treatment of musculoskeletal conditions. Research shows hydrocortisone and other white or opaque topical preparations transmit ultrasound energy poorly. Effective transmission of ultrasound is important in phonophoresis. Main Outcome measured: Samples of subcutaneous interstitial fluid were collected during and for 20 minutes following phonophoresis treatment. Cortisol concentrations were analyzed by an enzyme linked immune-assay (ELISA) test. Objective: Determine the subcutaneous cortisol concentration after two different phonophoresis treatments using a 2.5% hydrocortisone preparation. Design: Randomized design in which 22 healthy participants were assigned to receive a phonophoresis treatment where: 1) hydrocortisone …


Mtor Pathway Activation Following Sciatic Stimulation In Wild-Type And Desmin Knockout Mice, Daniel S. Nelson 2012 Brigham Young University - Provo

Mtor Pathway Activation Following Sciatic Stimulation In Wild-Type And Desmin Knockout Mice, Daniel S. Nelson

Theses and Dissertations

The 52 kDa intermediate filament protein desmin plays an important role in force transmission in skeletal muscle by connecting myofibrils at Z-lines and to the sarcolemma. Desmin content in muscle adapts to contractile activity and may be involved in cellular signaling mechanisms responsible for muscle growth. Purpose: To compare signaling responses of the mTOR pathway in wild type (WT) vs desmin knock out (KO) mice. Methods: WT (n=12) and KO (n=12) mice were exposed to high frequency electric stimulation of the left hindlimb to elicit an acute response of the mTOR pathway. Non-stimulated right hindlimbs were used as a within …


Psychological Well-Being And Dietary Quality Of College Women: Examining The Confounding Influence Of Sleep And Physical Activity, Whitney Ann Hebbert 2012 Brigham Young University - Provo

Psychological Well-Being And Dietary Quality Of College Women: Examining The Confounding Influence Of Sleep And Physical Activity, Whitney Ann Hebbert

Theses and Dissertations

Objective. To determine the relationship between overall psychological well-being and stress on diet quality among young adult women and to examine the potential confounding influence of season, physical activity and sleep on these relationships. Design/Participants. The study used a cross-sectional design. Three hundred and fifty-one women were recruited to participate in the study. All participants were university students (20.2 ± 1.6 y). Overall psychological well-being was assessed using the General Well-being Schedule (GWB) and the Perceived Stress Scale (PSS). Diet intake was measured using three 24-hour recalls over a seven day period. The Healthy Eating Index (HEI) was calculated to …


Determination Of Repetitive Jumping Intensity Relative To Measured Vo2max, Laura Igaune 2012 Western Kentucky University

Determination Of Repetitive Jumping Intensity Relative To Measured Vo2max, Laura Igaune

Masters Theses & Specialist Projects

To regular exercise and a healthy diet, the American Heart Association (AHA) strongly recommends rope jumping, and according to previous studies, rope jumping is considered a very strenuous exercise. Therefore the purpose of this study was to determine the steady state metabolic cost of repetitive jumping on the Digi-Jump machine, and to determine if exercise on this device is more or less strenuous than similar exercise with a jump rope. We also evaluated relative intensity of this type of exercise, based on each person’s VO2max as measured on a treadmill. Twenty – seven subjects completed two trials, one jumping …


Impaired Skeletal Muscle Blood Flow Control With Advancing Age In Humans: Attenuated Atp Release And Local Vasodilation During Erythrocyte Deoxygenation, Brett S. Kirby, Anne R. Crecelius, Wyatt F. Voyles, Frank A. Dinenno 2012 Duke University Medical Center

Impaired Skeletal Muscle Blood Flow Control With Advancing Age In Humans: Attenuated Atp Release And Local Vasodilation During Erythrocyte Deoxygenation, Brett S. Kirby, Anne R. Crecelius, Wyatt F. Voyles, Frank A. Dinenno

Health and Sport Science Faculty Publications

Rationale: Skeletal muscle blood flow is coupled with the oxygenation state of hemoglobin in young adults, whereby the erythrocyte functions as an oxygen sensor and releases ATP during deoxygenation to evoke vasodilation. Whether this function is impaired in humans of advanced age is unknown.

Objective: To test the hypothesis that older adults demonstrate impaired muscle blood flow and lower intravascular ATP during conditions of erythrocyte deoxygenation.

Methods and Results: We showed impaired forearm blood flow responses during 2 conditions of erythrocyte deoxygenation (systemic hypoxia and graded handgrip exercise) with age, which was caused by reduced local vasodilation. In young adults, …


External Work Is Deficient In Both Limbs Of Patients With Unilateral Pad, Shane R. Wurdeman, Sara A. Myers, Jason Johanning, Iraklis Pipinos, Nikolaos Stergiou 2012 University of Nebraska at Omaha

External Work Is Deficient In Both Limbs Of Patients With Unilateral Pad, Shane R. Wurdeman, Sara A. Myers, Jason Johanning, Iraklis Pipinos, Nikolaos Stergiou

Journal Articles

External work was utilized to measure differences between the unaffected and the affected limb in patients with unilateral peripheral arterial disease compared to healthy controls. Patients with unilateral peripheral arterial disease have shown deficits in peak joint powers during walking in the unaffected and affected legs. However, no research has detailed the amount of work that is being performed by each leg compared to healthy controls even though such an analysis would provide valuable information on the energy output from the affected and the unaffected legs. Two hypotheses were tested: a) the unaffected and affected leg would perform less work …


Effect Of Body Size And Exercise On Mood State, Alexandra Lachance 2012 University of Arkansas, Fayetteville

Effect Of Body Size And Exercise On Mood State, Alexandra Lachance

Graduate Theses and Dissertations

Exercising in the presence of nature (i.e., "green exercise"), has been shown to heighten the physiological and mental benefits of traditional exercise on non-obese individuals. The effects of green exercise on obese individuals are unknown. It is hypothesized that green exercise is more beneficial for obese (greater positive improvements in mental health scores), compared to non-obese individuals. For example, the benefits of green exercise could help lower feelings of depression, improve mood and self-esteem to increase the propensity of obese individuals to meet exercise recommendations. Accordingly, this study investigated the physiological and psychological effects of green exercise on 12 obese …


An Examination Of Finish Time Variation For Collegiate Cross Country National Championships By Gender, Kevin Riley Peters 2012 Boise State University

An Examination Of Finish Time Variation For Collegiate Cross Country National Championships By Gender, Kevin Riley Peters

Boise State University Theses and Dissertations

In cross country, women compete over shorter distances than men with little justification for these differences. The purpose of this study was to assess gender differences for the spread of finishing times and examine the appropriateness of shorter competition distances for females. Forty-six cross country national championship data sets (nmales = 10,788; nfemales = 10,884) from the NCAA (1999-2011) and NAIA (2005-2011) were utilized for analyses. Several measures of variation were computed to assess spread of finishing times data (i.e., Coefficient of Variation [CV]; Interpercentile Ranges [IR], and Rates of Separation [RS; IR divided by the distance …


Sensitivity Of The Wolf’S And Rosenstein’S Algorithms To Evaluate Local Dynamic Stability From Small Gait Data Sets: Response To Commentaries By Bruijn Et Al., Fabien Cignetti, Leslie M. Decker, Nikolaos Stergiou 2012 University of Nebraska at Omaha

Sensitivity Of The Wolf’S And Rosenstein’S Algorithms To Evaluate Local Dynamic Stability From Small Gait Data Sets: Response To Commentaries By Bruijn Et Al., Fabien Cignetti, Leslie M. Decker, Nikolaos Stergiou

Journal Articles

Assessing gait stability using the Largest Lyapunov Exponent (λ1) has become popular, especially because it may be a key measure in evaluating gait abnormalities in patient populations. However, clinical settings usually involve having small gait data sets and accurate determination of λ1 estimates from such sets is difficult. In an effort to address this issue, Cignetti et al.2 recently identified that λ1 estimates using the algorithm of Wolf et al.9 (W-algorithm) were more sensitive than those using the algorithm of Rosenstein et al.7 (R-algorithm) in order to capture age-related …


Peripheral Arterial Disease Affects The Frequency Response Of Ground Reaction Forces During Walking, Denise McGrath, Timothy N. Judkins, Iraklis Pipinos, Jason Johanning 2012 University of Nebraska at Omaha

Peripheral Arterial Disease Affects The Frequency Response Of Ground Reaction Forces During Walking, Denise Mcgrath, Timothy N. Judkins, Iraklis Pipinos, Jason Johanning

Journal Articles

Background—Walking is problematic for patients with Peripheral Arterial Disease. The purpose of this study was to investigate the frequency domain of the ground reaction forces during walking to further elucidate the ambulatory impairment of these patients.

Methods—Nineteen bilateral peripheral arterial disease patients and nineteen controls were included in this study. Subjects were matched for age and gait speed. Participants walked over a force plate sampling at 600Hz. PAD patients were tested before (pain-free condition) after the onset of claudication symptoms (pain). We calculated median frequency, frequency bandwidth, and frequency containing 99.5% of the signal for the vertical and …


Neural Responses To Food Pictures And Their Association With Dietary Intake, Edward Christenson 2012 Brigham Young University - Provo

Neural Responses To Food Pictures And Their Association With Dietary Intake, Edward Christenson

Theses and Dissertations

BACKGROUND: Food-related visual cues may affect eating behavior and energy intake. The purpose of this study was to determine the neural response to pictures of food and whether or not the neural responses were associated with energy intake. METHODS: Using a cross-sectional design, 60 adults participated in this study. Each participant reported to the laboratory in a fasted state, were fitted with a 128-electrode electroencephalogram (EEG) net, and were shown pictures grouped into three categories: high-calorie foods, low-calorie foods, and distractor pictures. These pictures were shown in random order. Furthermore, participants were shown these pictures in one passive condition and …


Shock Attenuation In Landing, Bryon Christopher Applequist 2012 University of Nevada, Las Vegas

Shock Attenuation In Landing, Bryon Christopher Applequist

UNLV Theses, Dissertations, Professional Papers, and Capstones

Shock attenuation (SA) has been well studied in activities such as walking and running (Chu, et al. 2004; Derrick, et al. 2004; Mercer, et al. 2003); however, there is a lack of research regarding SA during landing. Furthermore, there is lack of information regarding which structures attenuate shock. The purpose of this study was to examine SA among the leg-hip, hip-head, and leg-head segments during landing. Each subject (n=10, Age 26.3 ± 2.71 years, Height 1.68 ± 0.08 m, Mass 70.49 ± 16.03 kg) was instrumented with accelerometers at the leg, hip and forehead. Subjects then performed landings from three …


Frictional Forces Of A Fixed, Esthetic Orthodontic Appliance System, Brady Michael Nance 2012 University of Nevada, Las Vegas

Frictional Forces Of A Fixed, Esthetic Orthodontic Appliance System, Brady Michael Nance

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose: The demands of an all esthetic fixed orthodontic appliance system are ever increasing in today's world. Frictional values of an esthetic, fixed orthodontic appliance system are needed to evaluate their clinical effectiveness for orthodontic treatment. The aim of this study is to evaluate the frictional values of various esthetic orthodontic archwires ligated to an esthetic orthodontic bracket.

Methods: Three types of stainless steel and nickel titanium alloy (niti) esthetic orthodontic archwires (epoxy, poly, plastic) in four sizes (.016, .018, .017 x .025, .019 x .025 inches) were ligated to both a stainless steel bracket system and a ceramic (esthetic) …


Effects Of Obesity On Thermoregulation And Cardiovascular Function During Exercise In Females, Jon David Adams 2012 University of Arkansas, Fayetteville

Effects Of Obesity On Thermoregulation And Cardiovascular Function During Exercise In Females, Jon David Adams

Graduate Theses and Dissertations

Previous research has shown that obese individuals are at greater risk for heat illnesses because of impaired thermoregulation. However, laboratory studies investigating cardiovascular and thermoregulatory function in obese individuals are difficult to interpret because of low sample sizes and methodological concerns. The purpose of this study was to determine if there are differences in thermoregulatory and cardiovascular function between obese and non-obese females. Twenty-four females, 13 obese (43.3 ± 4 .3 % fat, 77.2 ± 13.7 kg) and 11 non-obese (27.8 ± 6.0 % fat, 55.7±6.7 kg), cycled for 60 min in a warm environment (~40°C, 30% humidity) at a …


The Relationship Between Sleep Deprivation, Food Motivation, And Energy Intake In Normal-Weight And Obese Females, Lora Light Romney 2012 Brigham Young University

The Relationship Between Sleep Deprivation, Food Motivation, And Energy Intake In Normal-Weight And Obese Females, Lora Light Romney

Theses and Dissertations

Objective: Sleep deprivation has been proposed as a potential correlate of obesity, particularly influencing energy intake. Therefore, the purpose of this study was to compare neural indices of attention related to food motivation and energy intake in normal-weight and obese women under two separate sleep conditions: 1) sleep-restricted (<5 hours) and 2) recommended sleep (~8 hours). This study used a combined cross-over and ex post facto design with condition order counter-balanced. Methods: Twenty-two normal-weight (age=30.9±9.5y, BMI=22.0±1.6 kg/m2) and 18 obese (age=29.7±10.7 y, BMI=36.4±5.3 kg/m2) women completed both sleep conditions. To confirm sleep levels, participants recorded sleep quality and quantity via sleep logs and wore a wrist actigraph. Following each condition, participants reported to the laboratory under the same fed state (energy shake ~10% of total daily needs) to verify they followed the sleep protocol. Subsequently, motivation for food was tested using electroencephalogram (EEG); participants completed a computerized passive-viewing task of food and flowers, while event-related brain potentials (ERPs) were recorded. After EEG testing, participants continued their normal routine but recorded all energy intake using weighed food scales. There were no instructions or limitations on dietary intake. Analyses included P300 and LPP amplitudes in response to picture type, total next day energy intake, and energy intake by several periods of the day. Results: Participants averaged 4.7±0.4 hours of sleep during the sleep-restricted condition and 7.7±0.3 hours during the recommended sleep condition (F=1057.02; P<0.0001). There was no group*condition interaction for next day food motivation (P300: F<2.896, P>0.09; LPP: F<2.967, P>0.093). Next day total energy intake also did not differ by group*condition (F=1.81; P=0.187). When participants were pooled, there was no difference in energy intake by sleep condition (F=0.00; P=0.953). However, when participants’ energy intake was analyzed during the lunch period (following testing to 1:30pm) there was a …


11/10/2012 Swosu Vs Harding (Wide Angle), Southwestern Oklahoma State University 2012 Southwestern Oklahoma State University

11/10/2012 Swosu Vs Harding (Wide Angle), Southwestern Oklahoma State University

Football Videos

Football video of the SWOSU vs Harding game on November 10, 2012 in Searcy, Ark. Footage is compiled from individual clips and has no audio.

Also attached is a PDF of the stats from the game, collected from: https://static.swosuathletics.com/custompages/stats/football/foot2012/12-11-10.htm


11/10/2012 Swosu Vs Harding (Endzone Angle), Southwestern Oklahoma State University 2012 Southwestern Oklahoma State University

11/10/2012 Swosu Vs Harding (Endzone Angle), Southwestern Oklahoma State University

Football Videos

Football video of the SWOSU vs Harding game on November 10, 2012 in Searcy, Ark. Footage is compiled from individual clips and has no audio.

Also attached is a PDF of the stats from the game, collected from: https://static.swosuathletics.com/custompages/stats/football/foot2012/12-11-10.htm


Patterns Of Genomic Loss Of Heterozygosity Predict Homologous Recombination Repair Defects In Epithelial Ovarian Cancer, V. Abkevich, K. M. Timms, B. T. Hennessey, M. S. Carey, Julie A. DeLoia, +15 additional authors 2012 Myriad Genetics, Inc.

Patterns Of Genomic Loss Of Heterozygosity Predict Homologous Recombination Repair Defects In Epithelial Ovarian Cancer, V. Abkevich, K. M. Timms, B. T. Hennessey, M. S. Carey, Julie A. Deloia, +15 Additional Authors

Exercise and Nutrition Sciences Faculty Publications

Background:

Defects in BRCA1, BRCA2, and other members of the homologous recombination pathway have potential therapeutic relevance when used to support agents that introduce or exploit double-stranded DNA breaks. This study examines the association between homologous recombination defects and genomic patterns of loss of heterozygosity (LOH).

Methods:

Ovarian tumours from two independent data sets were characterised for defects in BRCA1,BRCA2, and RAD51C, and LOH profiles were generated. Publically available data were downloaded for a third independent data set. The same analyses were performed on 57 cancer cell lines.

Results:

Loss of heterozygosity regions of …


11/03/2012 University Of Arkansas Monticello Vs Swosu (Wide Angle), Southwestern Oklahoma State University 2012 Southwestern Oklahoma State University

11/03/2012 University Of Arkansas Monticello Vs Swosu (Wide Angle), Southwestern Oklahoma State University

Football Videos

Football video of the University of Arkansas Monticello vs SWOSU game on November 3, 2012 in Weatherford, OK. Footage is compiled from individual clips and has no audio.

Also attached is a PDF of the stats from the game, collected from: https://static.swosuathletics.com/custompages/stats/football/foot2012/12-11-03.htm


11/03/2012 University Of Arkansas Monticello Vs Swosu (Tight Angle), Southwestern Oklahoma State University 2012 Southwestern Oklahoma State University

11/03/2012 University Of Arkansas Monticello Vs Swosu (Tight Angle), Southwestern Oklahoma State University

Football Videos

Football video of the University of Arkansas Monticello vs SWOSU game on November 3, 2012 in Weatherford, OK. Footage is compiled from individual clips and has no audio.

Also attached is a PDF of the stats from the game, collected from: https://static.swosuathletics.com/custompages/stats/football/foot2012/12-11-03.htm


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