Biomechanics Commons^™

An Investigation Of The Relationship Between Axonal Injury, Biomarker Expression And Mechanical Response In A Rodent Head Impact Acceleration Model, Yan Li

Wayne State University Dissertations

In the United States 1.4 million people sustain traumatic brain injury (TBI) each year, resulting in 235,000 hospitalizations and 50,000 fatalities annually. Traumatic axonal injury (TAI) is a serious outcome of TBI that accounts for 40-50% of hospitalizations due to head injury and one third of the mortality due to TBI, and it is difficult to diagnose and evaluate. The purpose of this dissertation is to determine mechanical injury predictors for TAI and identify potential biomarkers to evaluate TAI.

In this dissertation, a modified Marmarou impact acceleration injury model was developed to allow the monitoring of velocity of the impactor …

Dog Paddle Footfall Data, Frank E. Fish

Biology Data Repository

No abstract provided.

Dog Paddle Data Averages, Frank E. Fish

Biology Data Repository

No abstract provided.

Gait Intervention For Improvements In Human Top Speed Running, Michelle Buechner

Graduate Student Theses, Dissertations, & Professional Papers

Between individuals faster sprinting speeds are achieved by applying greater stance average forces against the running surface. Recent evidence further indicates that elite level performers also strike the ground with leg kinematics that differ from those of non-elites and that these leg movements act to enhance the force transients occurring in the milliseconds following foot-ground impact. I investigated whether sprint performance could be enhanced through a short term gait intervention, consisting of 3 laboratory training sessions wherein subjects (n = 6) completed 5 high-speed runs on an instrumented force treadmill at 90% of their measured top sprint. The subjects received …

A Multi-Directional Treadmill Training Program For Improving Gait, Balance, And Mobility In Individuals With Parkinson’S Disease: A Case Series, Kimberly Smith, Kurt Jackson, Kimberly Edginton Bigelow, Lloyd L. Laubach

Mechanical and Aerospace Engineering Faculty Publications

Treadmill training is a commonly used intervention for improving gait in people with Parkinson’s disease (PD). However, little is known about how treadmill training may also influence balance and other aspects of mobility.

The purpose of this case series was to explore the feasibility and possible benefits of multi-directional treadmill training for individuals with PD. Four participants (62.3 ± 6.5 yrs, Hoehn & Yahr 2-4) performed 8 weeks of treadmill training 3 times per week. Weeks 1-4 included forward walking only, while weeks 5-8 included forward and multi-directional walking. Participants were tested every 4 weeks on 4 separate occasions. Outcome …

The Relationship Between Axonal Injury, Biomarker Expression And Mechanical Response In A Rodent Head Impact Acceleration Model, Yan Li

Wayne State University Dissertations

In the United States 1.4 million people sustain traumatic brain injury (TBI) each year, resulting in 235,000 hospitalizations and 50,000 fatalities annually. Traumatic axonal injury (TAI) is a serious outcome of TBI that accounts for 40-50% of hospitalizations due to head injury and one third of the mortality due to TBI, and it is difficult to diagnose and evaluate. The purpose of this dissertation is to determine mechanical injury predictors for TAI and identify potential biomarkers to evaluate TAI.

In this dissertation, a modified Marmarou impact acceleration injury model was developed to allow the monitoring of velocity of the impactor …

Human Feeding Biomechanics : Intraspecific Variation And Evolution, Justin Ledogar

Legacy Theses & Dissertations (2009 - 2024)

This study examines feeding biomechanics in modern human crania and those of extinct early members of the human lineage in order to better understand the selective pressures that influenced human craniofacial evolution. Specifically, this study uses finite element analysis to examine: 1) human feeding performance, in terms bite force production and craniofacial strength; 2) intraspecific variation in human feeding biomechanics; 3) feeding biomechanics in fossil hominins, including Australopithecus sediba and Homo habilis, species that are potentially at the root of modern human lineage, and 4) the functional role of purported facial buttresses.

Methodology For Performing Whole Body Pmhs Underbody Blast Impact Testing, And The Corresponding Response Of The Hybrid Iii Dummy And The Finite Element Dummy Model Under Similar Loading Condition, Karthik Somasundaram

Wayne State University Theses

In recent wars, the use of improvised explosive devices and landmines has dramatically increased as a tactical measure to counter armored vehicles. These weapons not only deform and damage the vehicle structure but also produce serious vertical deceleration injuries to mounted occupants. The reported injury patterns largely differ from those in an automotive crash and are often more severe than those in other vertical loading scenarios such as pilot seat ejection, helicopter crash, parachute landing and fall from height. High kinetic energy predominately along the principal vertical (Z-axis) over a short duration makes the underbody blast (UBB) loading conditions unique …

Oncology Section Edge Task Force On Breast Cancer Outcomes: A Systematic Review Of Outcome Measures For Functional Mobility, Mary Insana Fisher, Jeannette Lee, Claire Davies, Hannah Geyer, Genevieve Colon, Lucinda Pfalzer

Physical Therapy Faculty Publications

Background: Breast cancer treatments in women with breast cancer often result in physical impairments that lead to activity limitations and participation restrictions. These limitations and restrictions manifest in impaired functional mobility skills that may impact survivorship. Thus, evaluation of functional mobility is an important part of survivorship care.

Purpose: To identify functional mobility outcome measures that possess strong psychometric properties and are clinically useful for examination of women treated for breast cancer.

Methods: Multiple electronic databases were searched for articles published after 1995. Studies were included if they reported psychometric properties, used clinically feasible methods, were performed on adults, and …

The Effects Of Home-Based Pilates In Healthy College-Age Females, Betsy Donahoe-Fillmore, Mary Insana Fisher, C. Jayne Brahler

Physical Therapy Faculty Publications

Objectives: To quantify and determine the effects of Pilates on core endurance, hamstring flexibility, balance, body composition/mass and perceived stress level in healthy college age females.

Study Design: Randomized controlled trial design.

Background: Emerging research on the Pilates technique is inconclusive regarding benefits to core endurance, flexibility, balance, body mass, and perceived stress.

Methods and Measures: Female college students (n=57; 18-35 years old) were randomly assigned to a Pilates group, who exercised at home with a DVD, or a control group who did not engage in Pilates practice. Core endurance, hamstring flexibility, balance, body composition and stress measurements were taken …

Flow Through The Nasal Cavity Of The Spiny Dogfish, Squalus Acanthias, L. L. Timm-Davis, Frank E. Fish

Biology Faculty Publications

The nasal cavity of spiny dogfish is a blind capsule with no internal connection to the oral cavity. Water is envisioned to flow through the cavity in a smooth, continuous flow pattern; however, this assumption is based on previous descriptions of the morphology of the olfactory cavity. No experimentation on the flow through the internal nasal cavity has been reported. Morphology of the head of the spiny dogfish (Squalus acanthias) does not suggest a close external connection between the oral and nasal systems. However, dye visualization showed that there was flow through the nasal apparatus and from the excurrent nostril …

Six Degree-Of-Freedom Analysis Of Hip, Knee, Ankle And Foot Provides Updated Understanding Of Biomechanical Work During Human Walking, Karl E. Zelik, Kota Z. Takahashi, Gregory S. Sawicki

Journal Articles

Measuring biomechanical work performed by humans and other animals is critical for understanding muscle–tendon function, jointspecific contributions and energy-saving mechanisms during locomotion. Inverse dynamics is often employed to estimate jointlevel contributions, and deformable body estimates can be used to study work performed by the foot. We recently discovered that these commonly used experimental estimates fail to explain whole-body energy changes observed during human walking. By re-analyzing previously published data, we found that about 25% (8 J) of total positive energy changes of/about the body’s center-of-mass and >30% of the energy changes during the Push-off phase of walking were not explained …

A Neuromechanics-Based Powered Ankle Exoskeleton To Assist Walking Post-Stroke: A Feasibility Study, Kota Z. Takahashi, Michael D. Lewek, Gregory S. Sawicki

Journal Articles

Background: In persons post-stroke, diminished ankle joint function can contribute to inadequate gait propulsion. To target paretic ankle impairments, we developed a neuromechanics-based powered ankle exoskeleton. Specifically, this exoskeleton supplies plantarflexion assistance that is proportional to the user’s paretic soleus electromyography (EMG) amplitude only during a phase of gait when the stance limb is subjected to an anteriorly directed ground reaction force (GRF). The purpose of this feasibility study was to examine the short-term effects of the powered ankle exoskeleton on the mechanics and energetics of gait.

Methods: Five subjects with stroke walked with a powered ankle exoskeleton …

A Pilot Study Investigating The Reasons For Playing Through Pain And Injury: Emerging Themes In Men’S And Women’S Collegiate Rugby, Leilani Madrigal, Jamie Robbins, Diane L. Gill, Katherine Wurst

Athletic Performance Research

Collegiate rugby is a competitive, collision sport, yet insufficient empirical evidence exists regarding participants’ perspectives on pain and injury. This study addressed male and female rugby players’ experiences with injury, and their views about playing through pain and injury. Eleven rugby players (five male; six female) competing in USA Rugby’s National College 7’s tournament participated in semi structured interviews, which were recorded, transcribed, and content-analyzed. Two major themes emerged: passion for sport and sport ethic. Passion for sport was composed of (a) love of the sport, (b) meaning of the sport, and (c) desire to be on the field. Sport …

A Methodology For Physically-Based Contact And Meniscus Properties In Rigid-Body Computational Knee Modeling, Stephen Wilson

Open Access Theses & Dissertations

Determining natural inner knee mechanics is a longstanding goal for researchers with applications to prevention and treatment of knee trauma and osteoarthritis. Physical testing has only provided limited information of knee mechanics due to technical challenges and cost. Modeling has been used for decades to obtain some of this otherwise inaccessible information, and recently finite element analysis (FEA) has become a popular means to this end. However, FEA requires time intensive mesh-creation and has large computational requirements. Ideally, model creation should be easy and simulations should be fast to allow for sensitivity analysis. Although allowing easier model creation and offering …

Effects Of Controlled Whole-Body Vibration Training On Reducing Risk Of Falls Among Young Adults With Obesity, Jose Jesus Munoz

Open Access Theses & Dissertations

Introduction: Among people with obesity, several factors increase the risk of falls: an abnormal body mass distribution, muscle weakness, and postural instability. Although standard exercise-based training could change these factors, a significant portion of people with obesity may be unable or unwilling to comply with long duration and high intensity training programs. Therefore, alternative training methods are highly demanded. Growing evidence supports that controlled whole-body vibration (CWBV) training can reduce risk of falls among older adults. No study has yet investigated the potential effect of CWBV training on reducing risk of falls among obese populations. The purpose of this study …

Trunk Postural Control In Unstable Sitting: Effect Of Sex And Low Back Pain Status, Christian Larivière, Dany H. Gagnon, Hakim Mecheri

Études primaires

Background

Adequate neuromuscular control of the lumbar spine is required to prevent lumbar injuries. A trunk postural control test protocol, controlling for the influence of body size on performance, was implemented to carry out between-subject comparisons. The aim of this study was to assess the effect of sex and low back pain status with the use of two measures of trunk postural control, the first based on chair motion, and the second based on trunk motion.

Methods

Thirty-six subjects (with and without low back pain) performed three 60-s trunk postural control trials with their eyes closed while seated on an …

Spatiotemporal Changes Posttreatment In Peripheral Arterial Disease, Sara A. Myers, Neil B. Huben, Jennifer M. Yentes, John D. Mccamley, Elizabeth E. Lyden, Iraklis I. Pipinos, Jason M. Johanning

Journal Articles

Accumulating evidence suggests revascularization of peripheral arterial disease (PAD) limbs results in limited improvement in functional gait parameters, suggesting underlying locomotor system pathology. Spatial and temporal (ST) gait parameters are well studied in patients with PAD at baseline and are abnormal when compared to controls. The purpose of this study was to systematically review and critically analyze the available data on ST gait parameters before and after interventions. A full review of literature was conducted and articles were included which examined ST gait parameters before and after intervention (revascularization and exercise). Thirty-three intervention articles were identified based on 154 articles …

The Effects Of Muscle Cross-Sectional Area On The Physical Working Capacity At The Fatigue Threshold, Meghan B. Barry, Jorge M. Zuniga, Makenna M. Brown, William M. Garnett, Zachary V. Hadden, Paul K. Nguyen, Geoffrey A. Supplee, Claire J. Svobada

Journal Articles

Purpose: The purpose of this study was to examine the effects of quadriceps cross-sectional area (CSA) of the dominant quadriceps muscle in the assessment of the physical working capacity at the fatigue threshold (PWCFT) during incremental cycle ergometry. Methods: Eighteen adults (9 men and 9 women; mean age ± SD = 20.5 ± 1.04 yr; mean body weight ± SD = 73.9 ± 18.2 kg; mean height ± SD = 172.3 ± 11.5 cm; mean dominant quadriceps CSA ± SD = 68.7 ± 14.5 cm2) performed an incremental cycle ergometry test to exhaustion while the electromyographic (EMG) signals …

Identification Of Intrinsic And Reflexive Contributions To Low-Back Stiffness: Medium-Term Reliability And Construct Validity, Christian Lariviere, Daniel Ludvig, Robert Kearney, Hakim Mecheri, Jean-Maxime Caron, Richard Preuss

Études primaires

This study aimed at testing the reliability and construct validity of a trunk perturbation protocol (TPP) that estimates the intrinsic and reflexive contributions to low-back stiffness. The TPP consists of a series of pseudorandom position-controlled trunk perturbations in an apparatus measuring forces and displacements at the harness surrounding the thorax. Intrinsic and reflexive contributions to low-back stiffness were estimated using a system identification procedure, leading to 12 parameters. Study 1 methods (reliability): 30 subjects performed five 75- s trials, on each of two separate days (eight weeks apart). Reliability was assessed using the generalizability theory, which allowed computing indexes of …