Food Science Commons^™

Human Breast Milk-Based Nutritherapy: A Blueprint For Pediatric Healthcare, Pravin Shende, Bhakti Khanolkar

Journal of Food and Drug Analysis

Human Breast Milk (HBM) is a storehouse of micronutrients, macronutrients, immune factors, microbiota and numerous other bioactive macromolecules. Fulfilment of optimum nutritional requirements of more than 240 million malnourished infants worldwide is possible via adequate amount (570-900 mL/d) of breast milk administration to infants in first few years of life. Technological advancements enable study of multiple components of HBM like stem cells, bioactive proteins, micro RNAs, immunoglobulins and epithelial cells to understand their role in enhancement of nutritional value of HBM. Furthermore, immunological and protective functions of HBM against various illnesses like diabetes, anemia, respiratory and cardiovascular abnormalities, otitis media …

Current And Potential Applications Of Simultaneous Dsc-Ftir Microspectroscopy For Pharmaceutical Analysis, Shan-Yang Lin

Journal of Food and Drug Analysis

Quality control (QC) is the most important key issue in the pharmaceutical industry to ensure the quality of drug products. Many analytical instruments and techniques in pharmaceutical analysis are applied to assess the quality and quantity of the drugs. In the current and future trends, a combination of digitization, automation and hyphenation with high throughput on-line performance will be the topics for the future of pharmaceutical QC. The hyphenated analytical techniques have recently received great attention as unique means to solve complex analytical problems in a short period of time. This review article is an update on the recent potential …

Comparative Metabolites Profiling And Fingerprinting Via A Multiplex Approach Of Uv And Lc/Ms Of Coffee Seeds In The Middle East And In Relation To Their Antioxidant Effects, Enas Elhawary

Theses and Dissertations

Coffee is a worldwide beverage of increasing consumption owing to its unique flavor and several health benefits. The current research aimed at investigating multiple bioactive compounds in coffee belonging to the two major species of Coffea, including C. arabica and C. canephora or C. Robusta, either green or roasted, along with 15 commercial specimens collected from the Middle East. Two platforms were employed, including ultra-high-performance liquid chromatography coupled to mass spectrometry (UHPLC/MS) and UV for profiling and fingerprinting, respectively. Identification of the UPLC/MS dataset was aided by using the global natural product social molecular networking (GNPS). A total of 91 …

Formulation Of Coffee Extract As Polymeric Nanoparticles And Studying Their Potential Biological Activities, Nouran Sharaf

Theses and Dissertations

Coffee extract was prepared and optimized (by solvent extraction) and subsequently entrapped into PLGA nanoparticles using single emulsion-solvent evaporation method (using Design Expert software). Dynamic Light Scattering, Scanning Electron Microscope, Fourier Transform-Infrared Spectroscopy and Folin Ciocalteau assay were used to characterize the NPs and to aid in selecting the optimum formulation conditions. The optimized NPs were in-vitro evaluated for their antimicrobial (by agar-well diffusion method), antioxidant (by DPPH assay) and anticancer (by MTT assay) activities. Finally, the release rate study was conducted for the NP sample showing the highly promising results.

The succeeded NP sample, in terms of the most …

Improvement Of Gut Barrier Function By Potato Anthocyanins Is Dependent On Gut Microbiota, Shiyu Li, Lavanya Reddivari

Department of Food Science Faculty Publications

Ulcerative colitis (UC) is characterized by chronic colonic inflammation, impaired barrier function and gut bacterial dysbiosis. Anthocyanin-containing potatoes have been shown to maintain the intestinal barrier function in colitic mice. However, the role of gut microbiota in the anti-colitic effects of anthocyanin- containing potatoes is not clear. This study evaluated the gut barrier protective efficacy of purple- and red-fleshed potatoes using a DSS- induced murine model of colitis with the intact and antibiotic-depleted microbiota.

Complexation With Polysaccharides Enhanced Polyphenol Gastrointestinal Stability And Activity, Wenyi Fu, Shiyu Li, Lavanya Reddivari

Department of Food Science Faculty Publications

Fruits and vegetables contain dietary polyphenols and polysaccharides. Accumulating evidence suggests that polyphenol- containing whole foods are protective against inflammation-promoted chronic colonic diseases. However, isolated polyphenols are less stable and may not confer the same gastrointestinal health benefits as that of the whole food matrix. Therefore, we hypothesized that the complex- ation of anthocyanins, a class of polypheonols, with polysaccharides would enhance colonic concentration and stability of anthocyanins, and attenuate impaired barrier function.

Partial Removal Of Phenolics Coupled With Alkaline Ph Shift Improves Canola Protein Interfacial Properties And Emulsion In In Vitro Digestibility, Jiang Jiang, Yunqing Nie, Xuemei Sun, Youling L. Xiong

Animal and Food Sciences Faculty Publications

The effect of polyphenol removal (“dephenol”) combined with an alkaline pH shift treatment on the O/W interfacial and emulsifying properties of canola seed protein isolate (CPI) was investigated. Canola seed flour was subjected to solvent extraction to remove phenolic compounds, from which prepared CPI was exposed to a pH₁₂ shift to modify the protein structure. Dephenoled CPI had a light color when compared with an intense dark color for the control CPI. Up to 53% of phenolics were removed from the CPI after the extraction with 70% ethanol. Dephenoled CPI showed a partially unfolded structure and increased surface hydrophobicity …

Impact Of Dry Hopping On Beer Flavor Stability, Bradley M. Titus, Larry A. Lerno, Jordan Beaver, Nadia K. Byrnes, H. Heymann, A. Oberholster

Chemistry Faculty Publications and Presentations

To investigate the chemical and sensorial impact of dry hopping time on typical pale ale, a standardized beer was produced and separated into ten vessels. Nine vessels were dry hopped, and one vessel remained un-hopped as a control. Impact of dry hopping contact time was investigated over 96 h. Polyphenols and iso-α-acid t/c ratio were analyzed in both Young and Aged beer samples. Total polyphenol content generally increased in both young and aged treatments compared to controls. Analysis of the t/c ratio suggests that both Young and Aged beers were chemically preserved to some degree after approximately 12 h at …

Zbulimi I Baktereve Listeria Monocytogenes Në Mostrat E Qumështit Në Rajonin E Prizrenit Sipas Metodës “Hytech Slide”, Vlera Dorambari

Theses and Dissertations

Në këtë studim, prania dhe prevalenca e Listeria monocytogenes u hetua në 10 mostrat e qumështit të lopës së papërpunuar të blerë nga tregjet e rrugëve në qendër të Prizrenit. Prania e L. monocitogjenes u zbulua duke përdorur metodën e Hytech Slide në L. monocitogjene u zbulua në 80% (8/10) të 10 mostrave të qumështit të analizuara.

Rezultatet e hulumtimit zbuluan se qumështi i papërpunuar i shitur në tregjet e rrugëve në qendër të Prizrenit mund të jetë burim i ndotjes me L. monocitogjene dhe të paraqesë një kërcënim të mundshëm për shëndetin publik.

Insects As A Sustainable Food Ingredient – Utilization Of Carrot Pomace, Identification Of Early Adopters, And Evaluation Of Mealworm Acceptability, Dominic Rovai

Master's Theses

Insects have been proposed as a sustainable alternative to livestock to help feed the growing population. Edible insects such as mealworms require less land and resources and can utilize food by-products to grow. While insects are consumed by over 2 billion people worldwide, they are not widely accepted in developed countries like the United States because of their unfamiliarity and the perception of disgust associated with entomophagy. The objectives of this research are to 1) grow mealworms using carrot pomace and determine an optimum diet for growth and nutritional composition, 2) identify and classify early adopters of insects, and propose …

Insects As A Source Of Phenolic Compounds And Potential Health Benefits, M C. Nino, Lavanya Reddivari, C Osorio, I Kaplan, A M. Liceaga

Department of Food Science Faculty Publications

The use of insects in traditional medicine and unveiling the chemical structure of the bright pigments in butterfly wings led to the discovery of bioactive phenolic compounds in the insect bodies. These metabolites have been found not only due to the insect absorption and metabolisation of the plant-derived phenolic present in their diet, but also from the ability of insects to synthesise phenolic compounds de novo through the sclerotisation process. Plant phenolics are secondary metabolites involved in the protection of tissues against UV radiation, herbivores, and pathogens, as well as pigmentation of fruits and flowers. These bioactive compounds exhibit antioxidant, …

Implementation Of Childhood Obesity Prevention And Control Policies In The United States And Latin America: Lessons For Cross-Border Research And Practice, Rafael Perez-Escamilla, Mireya Vilar-Compte, Elizabeth Rhodes, Olga L. Sarmiento, Camila Corvalan, Rachel Sturke, Susan Vorkoper

Department of Public Health Scholarship and Creative Works

Progress has been made in the development and widespread implementation of effective interventions to address childhood obesity, yet important challenges remain. To understand how the United States and Latin American countries achieved success in implementing obesity policies and programs (PAPs) and identify improvement opportunities using implementation science principles. We identified three comparative case studies: (1) front-of-food package labeling (Mexico and Chile); (2) Open Streets/play streets (Colombia and the United States); and (3) the Baby-Friendly Hospital Initiative (Brazil and the United States). Information from multiple sources (e.g., scientific and gray literature and key informant interviews) was synthesized to describe barriers, facilitators, …

Peanut Allergen Reaction Thresholds During Controlled Food Challenges In 2 Canadian Randomized Studies (Canada-Arm1 And Pisces), Derek K. Chu, Joseph L. Baumert, Steve L. Taylor, Julie A. Nordlee, Tina Nham, Jonathan Bramson, Sébastien La Vieille, Michael A. Abbott, Paul Spill, Andrea Marrin, Manel Jordana, Susan Waserman

Department of Food Science and Technology: Faculty Publications

In 2 randomized studies addressing peanut allergy (Canada-Food Allergy Risk Management 1 [NCT01812798] and Peanut Immunotherapy Starting in Canada, Evaluation and DiScovery [NCT0 1601522]), we quantified peanut allergen thresholds to food challenge using Bayesian stacked model averaging to inform policy and clinical practice. About 50% of patients tolerated more than 70 mg (~ ¼ peanut).

Overview Of The Microbiome Among Nurses Study (Micro-N) As An Example Of Prospective Characterization Of The Microbiome Within Cohort Studies, Christine Everett, Chengchen Li, Jeremy E. Wilkinson, Long H. Nguyen, Lauren J. Mciver, Kerry Ivey, Jacques Izard, Natalia Palacios, A. Heather Eliassen, Walter C. Willett, Alberto Ascherio, Qi Sun, Shelley S. Tworoger, Andrew T. Chan, Wendy S. Garrett, Curtis Huttenhower, Eric B. Rimm, Mingyang Song

Department of Food Science and Technology: Faculty Publications

A lack of prospective studies has been a major barrier for assessing the role of the microbiome in human health and disease on a population-wide scale. To address this significant knowledge gap, we have launched a large-scale collection targeting fecal and oral microbiome specimens from 20,000 women within the Nurses’ Health Study II cohort (the Microbiome Among Nurses study, or Micro-N). Leveraging the rich epidemiologic data that have been repeatedly collected from this cohort since 1989; the established biorepository of archived blood, urine, buccal cell, and tumor tissue specimens; the available genetic and biomarker data; the cohort’s ongoing follow-up; and …

Development Of A Portable Low-Moisture Food Pasteurization Device Using Rf Heating, Eric Jason Ohata

Master's Theses

Bacterial presence in low-moisture foods such as flour, cereals, baby formula, and spices, have become a concern due to sanitizing challenges. The food industry currently focuses on wet food sanitation as opposed to low-moisture foods because of bacteria’s inability to reproduce in low water activity media. Traditionally, food processing RF heating pasteurizes in mass quantities while an equivalent consumer device does not exist the market today. A consumer product would help eliminate food waste by providing an easy way to sanitize food and extend shelf life. The Portable Food Pasteurization (PFP) project is an interdisciplinary project involving the Electrical Engineering, …

A Meta-Analysis Of The Protein Components In Rattlesnake Venom, Anant Deshwal, Phuc Phan, Jyotishka Datta, Ragupathy Kannan, Suresh Kumar Thallapuranam

Chemistry & Biochemistry Faculty Publications and Presentations

The specificity and potency of venom components give them a unique advantage in developing various pharmaceutical drugs. Though venom is a cocktail of proteins, rarely are the synergy and association between various venom components studied. Understanding the relationship between various components of venom is critical in medical research. Using meta-analysis, we observed underlying patterns and associations in the appearance of the toxin families. For Crotalus, Dis has the most associations with the following toxins: PDE; BPP; CRL; CRiSP; LAAO; SVMP P-I and LAAO; SVMP P-III and LAAO. In Sistrurus venom, CTL and NGF have the most associations. These associations …

In Vitro Fecal Fermentation Patterns Of Arabinoxylan From Rice Bran On Fecal Microbiota From Normal-Weight And Overweight/Obese Subjects, Inah Gu, Wing Shun Lam, Daya Marasini, Cindi Brownmiller, Brett J. Savary, Jung Ae Lee, Franck Carbonero, Sun-Ok Lee

Food Science Faculty Publications and Presentations

Arabinoxylan (AX) is a structural polysaccharide found in wheat, rice and other cereal grains. Diets high in AX-containing fiber may promote gut health in obesity through prebiotic function. Thus, the impact of soluble AX isolated from rice bran fiber on human gut microbiota phylogenetic composition and short-chain fatty acid (SCFA) production patterns from normal-weight and overweight/obese subjects was investigated through in vitro fecal fermentation. Results showed that rice bran arabinoxylan modified the microbiota in fecal samples from both weight classes compared to control, significantly increasing Collinsella, Blautia and Bifidobacterium, and decreasing Sutterella, Bilophila and Parabacteroides. Rice …

Solanum Jamesii As A Food Crop: History And Current Status Of A Unique Potato, David Kinder, John Bamberg, Lisbeth Louderback, Bruce Pavlik, Alfonso Del Rio

Pharmacy Faculty Scholarship

Solanum jamesii is a wild potato found in the US southwest. There is ample evidence that this potato was used by ancestral Puebloans as a food source, where some researchers think it was used as a starvation food while others consider it to be regular food source. Currently this potato is being grown by Native Americans, notably the Navajo, as a specialty food as well as a food crop. There are several attributes to this potato that make it especially suitable for development as our climate changes and food needs become more demanding, including its drought tolerance and ability to …

Coupled Effects Of Hydrophilic Nano Silica Oxide And Anatase Nano Titanium Oxide On Strengths Of Oilwell Cement, Petro E Mabeyo, Jun Gu

Tanzania Journal of Science

The life of oilwells depends on the stability of cement sheath and bond strength with the formation and casing. Extreme subsurface conditions cause substantial stresses on the cement sheath resulting in a serious impact on well integrity. The recommended API cement for oilwell fails to provide the required durability of the cemented well due to such conditions. Supplementary cementitious materials such as nanoparticles are added to improve the cement for long-lasting zonal isolation. In this study, the compressive and shear bond strengths of oilwell cement containing nano-SiO2 and nano-TiO2 were studied at 80 °C for 3, 7, 14, and 28 …

Effects Of Xanthan Gum On Rheological Properties Of Aloe Vera-Moringa Leaf Juice Blends, Victor V Matabura, Leonard Mp Rweyemamu

Tanzania Journal of Science

Understanding the impacts of hydrocolloid agents on the rheological properties of nutraceutical beverages like Aloe vera-moringa juice blend is very useful for functional properties and product stability. To this end, the effects of xanthan gum on rheological properties in Aloe vera-moringa leaf juice blends were investigated using a Brookfield rheometer. Aloe vera-moringa leaf juice blends were prepared and then incorporated with xanthan gum at different ratios (w/w) of 0.2%, 0.4%, 0.6%, 0.8%, and 1%. The results revealed that the viscosity of Aloe vera-moringa juice blend was strongly affected by the xanthan gum addition. The viscosity profiles depicted a decreasing trend …