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Full-Text Articles in Biological Psychology

Cognitive Functioning In Well-Controlled Asthma, Erin Walsh Jan 2024

Cognitive Functioning In Well-Controlled Asthma, Erin Walsh

West Chester University Doctoral Projects

Asthma is a common lung disease that impacts lung functioning through inflammatory based mechanisms. Past research suggests that decreased blood oxygenation due to asthma attacks may impair cognitive capabilities (Irani et al., 2017). Moreover, the observed differences in cognition between those with and without asthma may be associated with disease severity or asthma control respectively in asthma populations. The current study explored differences in cognitive functioning between college students with and without self-reported asthma. Sociodemographic data, self-reported asthma severity, and measures of asthma control were collected. The current study did not find significant differences in measures of cognitive efficiency between …


Simulated Effects Of Postpartum Depression On Maternal-Infant Bonding: Mediated By Reward-Related Responses To Infant Facial Cuteness, Caitlin Harp Jan 2024

Simulated Effects Of Postpartum Depression On Maternal-Infant Bonding: Mediated By Reward-Related Responses To Infant Facial Cuteness, Caitlin Harp

Cal Poly Humboldt theses and projects

Infant cuteness (facial cuteness in particular) is linked to evolutionary adaptations to motivate caretaking and protective behaviors (Kringelbach et al., 2008). Previous neuroimaging work has demonstrated that infant cuteness activates reward-related regions in the brain (Glocker et al., 2009) and behavioral work suggests that the reward value of cuteness is linked to maternal tendencies (Hahn et al., 2015). It is estimated that 15% of new mothers experience postpartum depression (PPD) (Wisner et al., 2013), which impacts the mesolimbic system and is linked to anhedonia (i.e., reduced ability to experience pleasure). Based on the above literature, this study used a simulated …


Cerebrospinal Fluid Biomarkers Not Associated With Neurologic Compromise Among Mild Cognitively Impaired Reverters With Parkinson's Disease, Cameron Ryczek Dec 2023

Cerebrospinal Fluid Biomarkers Not Associated With Neurologic Compromise Among Mild Cognitively Impaired Reverters With Parkinson's Disease, Cameron Ryczek

Electronic Theses, Projects, and Dissertations

Parkinson's Disease (PD) is a neurodegenerative disease characterized by motor (e.g. tremors) and non-motor symptoms (e.g. cognitive impairment). PD patients' change in cognitive functioning can be observed using the following classifications: cognitively intact, mild cognitive impairment (MCI), or dementia (PDD). MCI has many subtypes, one of which is MCI reversion which is defined as those with MCI at one time point reverting to cognitively intact later. While there is limited research into the utility of MCI reversion and its relationship with cerebrospinal fluid (CSF) biomarkers in PD, this study will begin to elucidate this relationship. To this end, data from …


The Effects Of Transcranial Direct Current Stimulation (Tdcs) On Facial Expression Approach/Avoidance In College Students And Faculty With Broad Autism Phenotype, Nicole R. Baker Aug 2023

The Effects Of Transcranial Direct Current Stimulation (Tdcs) On Facial Expression Approach/Avoidance In College Students And Faculty With Broad Autism Phenotype, Nicole R. Baker

Electronic Theses and Dissertations

Transcranial Direct Current Stimulation (tDCS) has been proposed as an alternative noninvasive therapy for individuals with autism. This study trained brain activity in college students and / or faculty with Broad Autism Phenotype (BAP) while eye tracking data was collected. The purpose of this study was to determine if tDCS training to the frontal lobes could increase approach toward social interactions in adults classified as BAP as demonstrated by eye-tracking measures in response to faces and gaze fixation. The study included 21 total participants recruited from the Science, Technology, Engineering, and Math (STEM) courses / professions at a Regional East …


Examination Of Performance Validity And The Relationship To Cognition And Symptoms In Schizophrenia Spectrum Disorders, Erick A. Rogers Aug 2023

Examination Of Performance Validity And The Relationship To Cognition And Symptoms In Schizophrenia Spectrum Disorders, Erick A. Rogers

UNLV Theses, Dissertations, Professional Papers, and Capstones

Approximately one-in-five individuals with psychotic disorders (i.e., schizophrenia spectrum disorders [SSD]) fail performance validity indicators (PVIs) during neurocognitive testing. Ensuring the validity of neurocognitive test results is necessary if the test scores are to be of use for diagnostic consideration, intervention selection and planning, predicting outcomes, and following changes in cognition over time in response to intervention, spontaneous recovery, or disease progression. PVIs are designed to require only a minimum level of engagement with the evaluation, which means nearly everyone is expected to “pass,” even those with moderate to severe brain damage. Traditional interpretations of PVI failure suggest a noncredible …


Adverse Childhood Experiences(Aces) And Nonverbal Reasoning Skills, Monika Malinowska Jun 2023

Adverse Childhood Experiences(Aces) And Nonverbal Reasoning Skills, Monika Malinowska

Dissertations

Severe stress and interpersonal traumatic experience in childhood have a cascade effect on an individual's physical and mental health. There is evidence that people with complex adverse childhood experiences have diminished cognitive abilities. However, there are few studies on the effects of Adverse Childhood Experiences (ACE) on non-verbal reasoning skills. This study aimed to assess the relationships between ACEs, non-verbal reasoning skills, and academic achievement.


Does A Single Night Of Mindfulness Meditation Improve Sleep And Stress In Female College Students?, Koushik Thudi May 2023

Does A Single Night Of Mindfulness Meditation Improve Sleep And Stress In Female College Students?, Koushik Thudi

Psychological Science Undergraduate Honors Theses

Several recent studies have shown that mindfulness-based practices have been effective in treating sleep problems. However, these studies have primarily looked at multi-component interventions that take place over several weeks or months. No studies have evaluated the efficacy of short-term mindfulness-based practices on sleep the same night. This study aims to do just that. The sample consisted of 10 students attending the University of Arkansas. All participants slept in a sleep laboratory on two consecutive weekday nights. During one night, they completed a mindfulness-based exercise. The other night, they completed a similar control task (counterbalanced). Polysomnography-based sleep data were collected …


Do Traits Of Autism Spectrum Disorder In The Typically Developing Population Relate To Early Face Processing As Measured By The N170 And N250 Neural Signals?, Anna Murdock Apr 2023

Do Traits Of Autism Spectrum Disorder In The Typically Developing Population Relate To Early Face Processing As Measured By The N170 And N250 Neural Signals?, Anna Murdock

Honors Theses

This exploratory study used electrophysiology to examine whether traits associated with autism spectrum disorder (ASD) in the typically developing population are related to early face processing. Previous literature has found mixed results about whether event-related potential (ERP) components appear differently in people with ASD, but two components that might be related to the observed deficit in face processing are the N170 component, which reflects the structural encoding of faces, and the N250 component, which reflects the individuation of faces. The present study analyzed data collected as part of the PURSUE EEG database. As part of the database, participants completed the …


Mechanisms Linking Threat- And Deprivation-Related Childhood Adversity And Depression: The Biopsychosocial Model, Cut N. Kemala, Marijtje L.A. Jongsma, Donny Hendrawan, Eni Becker Apr 2023

Mechanisms Linking Threat- And Deprivation-Related Childhood Adversity And Depression: The Biopsychosocial Model, Cut N. Kemala, Marijtje L.A. Jongsma, Donny Hendrawan, Eni Becker

Psychological Research on Urban Society

Childhood adversity involves a wide range of negative experiences that pose a serious threat to a child’s wellbeing. It has been consistently shown to predict (chronic) depression in subsequent stages of development, but mechanisms underlying the relationship are still less clear. Moving from a cumulative approach of lumping heterogeneous categories of childhood adversity to a dimensional approach of classifying negative experiences into two major dimensions (threat and deprivation) has facilitated the identification of specific processes by which childhood adversity can predict depression. This review aims to provide an integrative overview of how childhood adversity increases the risk for depression using …


A Theoretical Basis For Understanding And Researching The Relationship Between Music, Stress, And Biofeedback, Frederick Wang Jan 2023

A Theoretical Basis For Understanding And Researching The Relationship Between Music, Stress, And Biofeedback, Frederick Wang

Antioch University Dissertations & Theses

Music’s ability to influence emotional states and physical arousal has become an increasingly popular area of study. The wealth of literature around music and stress suggests a significant amount of interest in leveraging music to manage stress. However, as attention increases, the robustness of research becomes an increasing concern. This study investigates the current literature and proposes recommendations for the future studying of the psychological and physiological impacts of music as it relates to stress reduction. Existing literature was reviewed with a focus on the operationalization of key concepts of music and stress. The analysis showed considerable discrepancies in research …


Barriers To Care, Depressive Symptoms, And Moderating Factors Among Patients With Esrd, Amarachukwu O. Nwangwu Apr 2022

Barriers To Care, Depressive Symptoms, And Moderating Factors Among Patients With Esrd, Amarachukwu O. Nwangwu

Honors Theses

End-Stage Renal Disease (ESRD) is the fifth and final stage of Chronic Kidney Disease (CKD) and has been reported to have the highest prevalence rate in the United States, with about 2,242 cases per million in the total population in 2017 (Johansen et al., 2021). Current studies document a high prevalence of depression among patients with ESRD which may lead to increased mortality (Shirazian et al., 2017). Additionally, barriers in access to care, which may be understood as the barriers that prevent individuals from seeking mental health services, has been linked to increased levels of undertreatment (Clement et al., 2012). …


Borderline Personality Symptoms And Relationship Threat: The Moderating Role Of Perceived Parental Rejection, Elsa Baumgartner Apr 2022

Borderline Personality Symptoms And Relationship Threat: The Moderating Role Of Perceived Parental Rejection, Elsa Baumgartner

Departmental Honors & Graduate Capstone Projects

Individuals with borderline personality disorder (BPD) often perceive relationship threats more intensely, resulting in increased emotional reactivity. However, this link has never been examined with physiological measures in “real time,” nor have reports of perceived parental rejection ever been investigated as a potential moderator of this link. To fill this gap, the present study induced romantic relationship threat, after which participants completed an emotional reactivity task while electroencephalography data were recorded. Results reveal that higher levels of BPD features were associated with increased emotional reactivity, indicated by larger late positive potential (LPP) amplitudes, to negative stimuli in the face of …


Heart Rate Variability Following Treatment For Ptsd: Testing The Polyvagal Theory, Brittany F. Goodman Apr 2022

Heart Rate Variability Following Treatment For Ptsd: Testing The Polyvagal Theory, Brittany F. Goodman

Dissertations

Posttraumatic stress disorder (PTSD) has been linked to lower heart rate variability (HRV), including measures of vagal tone. Treatments targeting the autonomic nervous system (ANS) have demonstrated efficacy in improving vagal tone, but it is less clear whether similar effects can also be achieved with cognitive therapies. The polyvagal theory has suggested that symptoms of social dysfunction are linked to vagal tone through a phylogenetically organized response to stress. HRV was collected during rest, reactivity (exposure to personalized trauma scripts), and recovery using a scripted imagery paradigm in female PTSD positive physical and sexual assault survivors (N = 41) …


Parent-Prompted Dysregulation: Do Parents Serve As Cues For Dysregulation In Some Children?, Daniel Lee Jan 2022

Parent-Prompted Dysregulation: Do Parents Serve As Cues For Dysregulation In Some Children?, Daniel Lee

Pitzer Senior Theses

Children occasionally encounter dysregulation when interacting with their parents in relatively neutral or positive scenarios. Given that the cause of dysregulation is usually relational, meaning it is often cued by someone who is seen to have power or control over the person, children could be particularly susceptible to dysregulation in the presence of their parents. However, when examining the existing literature, there appeared to be a lack of research and knowledge concerning this topic, with much of the literature focusing on the effect of child stressors on parental dysregulation. As a result, the term parent-prompted dysregulation was developed to refer …


The Influence Of Emotion Regulation And Neural Cognitive Control On Distress Tolerance, Alicia L. Milam Dec 2021

The Influence Of Emotion Regulation And Neural Cognitive Control On Distress Tolerance, Alicia L. Milam

Psychology Theses & Dissertations

Tolerance of negative emotions has been associated with transdiagnostic negative mental health outcomes. Theory and research implicate emotion regulation and cognitive control as factors in tolerance of negative emotions. But their unique contributions to tolerance of negative emotions and interdependency have been unclear due to methodological limitations. This study aimed to explicate cognitive and emotional factors affecting distress tolerance in a non-clinical sample of emerging adults. Undergraduate psychology students completed self-report measures of emotion regulation ability and tolerance of negative emotions. The N2 ERP component elicited by a Go-NoGo task was also used as a neurophysiological marker of cognitive control …


A Randomized Controlled Trial Of Psychological Outcomes Of Mobile Guided Resonant Frequency Breathing In Young Adults With Elevated Stress During The Covid-19 Pandemic, Al Amira Safa Shehab Sep 2021

A Randomized Controlled Trial Of Psychological Outcomes Of Mobile Guided Resonant Frequency Breathing In Young Adults With Elevated Stress During The Covid-19 Pandemic, Al Amira Safa Shehab

Dissertations, Theses, and Capstone Projects

Deep breathing practices have shown promise in reducing stress, anxiety, and depression in different populations, including young adults. Specifically, resonant frequency breathing can exert an impact on stress response systems through the vagus nerve and the hypothalamo-pituitary-adrenal (HPA) axis. This may induce reductions in stress and improvement in emotion regulation. Young adults, including college students, tend to be at a higher risk for psychological distress, as they face several psychosocial challenges. The COVID-19 pandemic has imposed new and unique stressors that resulted in higher levels of stress and emotional symptoms and it has been shown that this may have placed …


Exploration Of Patient Variables And Characteristics Best Suited For Medical Marijuana Treatment For Anxiety And Depressive Disorders, Corey Gazoo Aug 2021

Exploration Of Patient Variables And Characteristics Best Suited For Medical Marijuana Treatment For Anxiety And Depressive Disorders, Corey Gazoo

Dissertations

Individuals with posttraumatic stress, anxiety and depressive disorders are currently being prescribed medical marijuana as a treatment in many states across the United States. However, marijuana is still considered a schedule one narcotic by the Drug Enforcement Administration and federal government, which provides several barriers and challenges to conduct research such as approval from the U.S. Food and Drug Administration and following guidelines from the National Institute on Drug Abuse issued by the DEA. Additionally, individuals prescribed medical marijuana for mental health disorders are not always thoroughly instructed on the type of medical marijuana, the dosage, and how frequently to …


Medication Versus Brain-Based Treatment: Evaluation Treatment Preferences Of Parents Of Children With Adhd, Rebecca Recio-Swift Jul 2021

Medication Versus Brain-Based Treatment: Evaluation Treatment Preferences Of Parents Of Children With Adhd, Rebecca Recio-Swift

Electronic Theses and Dissertations

Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most prevalent neurodevelopmental disorders across the world. Currently, treatment for ADHD mostly consists of either medication or behavioral therapy or a combination of both. However, research has shown that medication used as therapy for the treatment of ADHD has side effects which parents deem undesirable for their children. Therefore, recent research has focused on patient and parent preferences. Studies have found that behavioral or other treatment options may often be chosen over medications. These same studies have documented the characteristics of parents that prefer certain treatments for their children. The purpose of this …


Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell Jul 2021

Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell

All NMU Master's Theses

Anxiety and anxiety related disorders are increasing at a drastic rate in the past decade, with the NIMH reporting that 31.1% of U.S. adults will experience an anxiety disorder at some point in their lives. Anxiety is commonly characterized by increased attention bias to threat. Attention Bias Modification (ABM) is a new treatment used to reduce individual’s attention bias towards threat. The extent to which ABM leads to underlying neural changes is still unknown. The cerebellum is a neglected brain structure, with new research provides evidence that cerebellum’s functional connectivity and shared networks with threat processing regions has a direct …


Learning To Feel Safe: A Translational Study Of The Influence Of Safety Learning On Anxiety-Related Overgeneralized Fear, Hyein Cho Jun 2021

Learning To Feel Safe: A Translational Study Of The Influence Of Safety Learning On Anxiety-Related Overgeneralized Fear, Hyein Cho

Dissertations, Theses, and Capstone Projects

Anxiety disorders are among the most common mental health diagnoses, affecting about a third of the population in their lifetime. However, approximately a third of individuals with anxiety do not respond to current treatment approaches, highlighting the need to identify additional potential therapeutic mechanisms. Safety learning is one such mechanism, but methodological challenges and a dearth of research have prevented the field from advancing the understanding of the role of safety learning in the etiology and remediation of anxiety disorders. Animal research, using single-cued safety learning paradigms, has yielded promising early findings, demonstrating that safety learning directly reduces anxiety-related behaviors …


Exploring Tactile Art-Making With Deafblind Students And Their Families: An Opportunity For Creative Play, Alice Rodgers May 2021

Exploring Tactile Art-Making With Deafblind Students And Their Families: An Opportunity For Creative Play, Alice Rodgers

Expressive Therapies Capstone Theses

The impact of a deafblind diagnosis on an individual’s mental health and the well-being of the family involved can be profound. However, current research and available literature for the mental health treatment and therapy practices of deafblind persons and their families is limited (Kyzar et al., 2016; “WFDB Global Report 2018,” n.d.). This thesis used the Leeds Family Psychology and Therapy Service principles (Leeds FPTS) and the Expressive Therapies Continuum with established deafblind teaching strategies to facilitate an original arts-based community project entitled: “Things We Like.” This project provided an opportunity for deafblind students (ages three to 22) and their …


Reiki For Recovery: Incorporating Japanese Health Practices To Increase Contemporary Resiliency In American Health, Leif Peterson May 2021

Reiki For Recovery: Incorporating Japanese Health Practices To Increase Contemporary Resiliency In American Health, Leif Peterson

Master's Projects and Capstones

The Japanese health practice of Reiki attempts to maximize the latent ability of the human system to heal itself. The Reiki system, established over a century ago, combines multiple Asian health traditions, experimenting with practices that maximize the natural processes of the body to perform its own repairs. Reiki encourages healthy behaviors that balance the mind and body, return the human system to a lowered stress level, and allow for an optimal recovery state for the patient. This paper illustrates how this Japanese health-affirming method can be integrated and utilized within existing health and medical practices. An area that is …


Everyday Memory In People With Down Syndrome, Yingying Jennifer Yang, Zachary M. Himmelberger, Trent Robinson, Megan Davis, Frances Conners, Edward Merrill Apr 2021

Everyday Memory In People With Down Syndrome, Yingying Jennifer Yang, Zachary M. Himmelberger, Trent Robinson, Megan Davis, Frances Conners, Edward Merrill

Department of Psychology Faculty Scholarship and Creative Works

Although memory functions in people with Down Syndrome (DS) have been studied extensively, how well people with DS remember things about everyday life is not well understood. In the current study, 31 adolescents/young adults with DS and 26 with intellectual disabilities (ID) of mixed etiology (not DS) participated. They completed an everyday memory questionnaire about personal facts and recent events (e.g., school name, breakfast). They also completed a standard laboratory task of verbal long-term memory (LTM) where they recalled a list of unrelated words over trials. Results did not indicate impaired everyday memory, but impaired verbal LTM, in people with …


The Human Instinct To Resilience: Clinical And Evolutionary Efficacy Of Intrinsically Motivated Stressor Exposure, Brady Barley Feb 2021

The Human Instinct To Resilience: Clinical And Evolutionary Efficacy Of Intrinsically Motivated Stressor Exposure, Brady Barley

Ramifications

Environmental stressors threaten optimal behavioral functioning, and thus contribute to the development of psychopathology and exert evolutionary selection pressure. Voluntary stressor exposure has the efficacious effect of increasing resilience to future stressors in humans and other animals. This theoretical paper considers the hypothesis that intrinsic motivation toward behaviors requiring voluntary stressor exposure mitigates evolutionary selection pressure exerted by environmental stressors by inducing neural and neuroendocrine plasticity which results in increased resilience. In this view, intrinsically motivated stressor exposure is both efficacious and innate. Empirical and theoretical support for this hypothesis suggest that humans possess an instinct to resilience. Stress-related disorders …


Antecedents Of Borderline Personality Disorder And Antisocial Personality Disorder: An Examination Of Gene X Environment Interactions, Amy L. Medina Feb 2021

Antecedents Of Borderline Personality Disorder And Antisocial Personality Disorder: An Examination Of Gene X Environment Interactions, Amy L. Medina

Dissertations, Theses, and Capstone Projects

Current thinking suggests that genotypes associated with impulse-control disorders and negative emotionality, such as monoamine oxidase-a (MAOA), interact with negative early environmental factors like childhood maltreatment and develop into the disorders know as Borderline Personality Disorder (BPD) and Antisocial Personality Disorder (ASPD). Using existing data from a prospective cohort design study of the consequences of child abuse and neglect, participants (N = 896 represent individuals with documented histories of child abuse and neglect and a matched comparison group that were followed up into adulthood and interviewed. A subsample of 631 participants gave permission for DNA extraction and analyses during …


The Interactive Effects Of Brain-Derived Neurotrophic Factor (Bdnf) Polymorphisms And Posttraumatic Stress Disorder On Neurocognitive Functioning In U.S. Military Veterans, Colton Shafer Rippey Jan 2021

The Interactive Effects Of Brain-Derived Neurotrophic Factor (Bdnf) Polymorphisms And Posttraumatic Stress Disorder On Neurocognitive Functioning In U.S. Military Veterans, Colton Shafer Rippey

Theses and Dissertations--Psychology

Posttraumatic Stress Disorder (PTSD) is associated with mild-to-moderate deficits in neurocognitive functioning. Single nucleotide polymorphisms (SNPs) in the brain-derived neurotrophic factor (BDNF) gene, namely, the Met allele, may also be associated with mild deficits in neurocognitive functioning. However, findings are inconsistent and may be sensitive to environmental epigenetic moderators such as psychopathology.

The current study analyzed data from European-American U.S. military veterans (n = 1,244) who participated in the 2011 National Health and Resilience in Veterans Study (NHRVS). Multivariate analyses of covariances were conducted to evaluate the unique and interactive effects of the Met allele and probable PTSD on …


The Impact Of Exercise On Adolescents With Depression: A Systematic Review Of The Literature, Matthew P. Kloeris Jan 2021

The Impact Of Exercise On Adolescents With Depression: A Systematic Review Of The Literature, Matthew P. Kloeris

Theses and Dissertations

The purpose of the present study was to summarize and synthesize the research that pertains to the impact of aerobic exercise on adolescents with depression. This review addressed aerobic exercise as a mental health treatment, such as differences between (a) post-intervention and follow-up response and remission rates; (b) exercise in lieu of psychotherapy or exercise as an adjunct to psychotherapy; and (c) response and remission rates amongst minority gender and racial and ethnic groups. The search results produced a total of 2,122 articles. Of which, eight articles were eligible for the present systematic review. Based on the results, it appears …


Do You Copy? Post-Traumatic Stress Disorder, Auditory Processing, And Heart Rate Variability, Lyndsey Johnson Jan 2021

Do You Copy? Post-Traumatic Stress Disorder, Auditory Processing, And Heart Rate Variability, Lyndsey Johnson

UNF Graduate Theses and Dissertations

Self -report measures used in PTSD research have the potential to limit the degree of symptom severity in military veterans, especially as there is often underreporting in this population (Kline, Falca-Dodson, Susner et al., 2010). Polyvagal Theory provides a framework assessing if physiological measures can tap into PTSD Symptomology (Porges, 1995). It is therefore hypothesized that lower scores on auditory processing tests will be positively correlated with higher scores on Stress and PTSD measures. Additionally, it is thought that lower scores on auditory processing tedts as well as higher scores on PTSD and Stress Measures will be positively correlated with …


Complex Trauma In Childhood And Its Relationship To Emotion Regulation And Distress Tolerance In College Students, Elizabeth Lombardo Dec 2020

Complex Trauma In Childhood And Its Relationship To Emotion Regulation And Distress Tolerance In College Students, Elizabeth Lombardo

USC Aiken Psychology Theses

Objective: The influence of childhood trauma has been found to be related to difficulties in emotion regulation and distress tolerance in young adulthood (Berenz et al., 2018a, 2018b). Research has shown that childhood abuse and adversities such as neglect or emotional abuse results in impaired processes related to the development of emotion regulation and efficient interpersonal skills, while also resulting in symptoms reflecting disordered affective self-regulation (Cloitre et al., 2009; Shipman, Edwards, Brown, Swisher, & Jennings, 2005; Shipman, Zeman, Penza, & Champion, 2000). Research has examined emotional regulation and distress tolerance in the context of childhood trauma but has not …


Neurodevelopmental Mechanisms Of Adverse Trauma Outcomes In Emerging Adulthood, Olena Kleshchova Sep 2020

Neurodevelopmental Mechanisms Of Adverse Trauma Outcomes In Emerging Adulthood, Olena Kleshchova

Dissertations, Theses, and Capstone Projects

Background: Exposure to traumatic stress and adversity during the formative years of development can have adverse effects on mental health, neuroendocrine stress system function, and the brain, that persist into adulthood. One candidate mechanism that might confer vulnerability to enduring adverse outcomes of early life trauma is disruption of normal brain maturation. As the brain matures, functional interactions among brain regions change until the functional brain architecture (i.e., the functional connectome) reaches a mature state in adulthood. Given that different neural circuits have distinct developmental trajectories and sensitive periods, traumatic stress at a given point in development might have …