Artificial Intelligence and Robotics Commons^™

Clinicians In The Loop Of Medical Ai, W. Nicholson Price Ii

Articles

As medical AI begins to mature as a health-care tool, the task of governance grows increasingly important. Ensuring that medical AI works, works where it’s used, and works for the patient in the moment is a challenging, multifaceted task. Some of this governance can be centralized—in review by FDA or by national accreditation labs, for instance. Some must be local, performed by the hospital or health system about to use the product in their own, unique environment. But a large amount of governance is left to the individual provider in the room, the human in the loop who presumably knows …

Do Specialized Medical Llms Demand A Radically New Approach Under The Eu's Medical Device Regulation, Hannah Louise Smith, W. Nicholson Price Ii

Articles

We examine the arguments made by Onitiu and colleagues concerning the need to adopt a “backward-walking logic” to manage the risks arising from the use of Large Language Models (LLMs) adapted for a medical purpose. We examine what lessons can be learned from existing multi-use technologies and applied to specialized LLMs, notwithstanding their novelty, and explore the appropriate respective roles of device providers and regulators within the ecosystem of technological oversight.

Boden Lecture: Taxation Of Autonomous Artificial Intelligence, Reuven S. Avi-Yonah, Lucas Brasil Salama, Herbert Snitz, W. Robert Thomas

Articles

This Article proposes that tax can be a useful supplement to other measures to regulate Autonomous Artificial Intelligence (AAI) and limit its potential harmful effects. This proposal differs from command-and-control regulation of AAI along the lines of European Union legislation that may unduly limit the development of AAI. It also differs from existing proposals to tax AAI to generate revenue to help workers displaced by AAI programs, or to tax the data used by AAI The proposal is based on granting AAI programs like ChatGPT separate legal personhood, like corporate personhood, while incentivizing or requiring their corporate owner to place …

Synthetic Data Generation Of Health And Demographic Surveillance Systems Data: A Case Study In A Low- And Middle-Income Country, Dorcas G. Mwigereri, Nigel T. Kamotho, Akbar K. Waljee, Ryan T. Rego, Eileen M. Weinheimer-Haus, Farhana Alarakhiya, Anthony K. Ngugi, W. Nicholson Price, Ji Zhu, Stephen Peter Wong, Geoffrey H. Siwo

Articles

Objective: To evaluate effectiveness of open-source generative models in producing high-quality tabular synthetic data using a Health and Demographic Surveillance System (HDSS) dataset from rural Kenya, as a proof of concept in a low- and middle-income (LMIC) setting.

Materials and Methods: Three open-source models (CTGAN, TableGAN, and CopulaGAN) were used to generate synthetic data from the Kaloleni/ Rabai HDSS dataset. To assess the quality of the synthetic datasets generated by each model, we performed fidelity, utility, and privacy tests.

Results: CTGAN outperformed the other models, producing synthetic data that closely mirrored the statistical properties of the real dataset while preserving …

The Future Of Ai Regulation In Drug Development: A Comparative Analysis, Gabriela Lenarczyk, Timo Minssen, W. Nicholson Price Ii, Arti Rai

Articles

As artificial intelligence (AI) transforms drug development, regulatory frameworks are evolving to oversee its implementation, particularly at the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). This paper makes three contributions to understanding emerging regulatory approaches. First, we offer a comparative analysis of how these agencies have responded to AI-driven advances, incorporating new US executive orders and the European Union (EU)’s AI Act. Second, we propose a novel analytical framework to understand regulatory divergence: the FDA’s flexible, dialog-driven model contrasts with the EMA’s structured, risk-tiered approach, reflecting broader institutional and political-economic differences. While the former encourages …

Neural And Computational Approach To Understanding Environmental Modulation Of Behavioral Identity In Zebrafish, John W. Hageter

Graduate Theses, Dissertations, and Problem Reports (ETD)

Organisms rely on behavior for survival. Animals engage in behaviors that allow for feeding, mating, exploring and navigating their environment among others. Necessary for these behaviors to develop are the environmental factors and underlying circuitry which make behavior possible. Specifically, how the environment guides underlying neural circuitry to develop unique facets or phenotypes of a larger behavior are key to understanding why unique behaviors exist. In this thesis, I build foundational evidence for determining these mechanisms through the use of the zebrafish local search behavior. This is a behavior that zebrafish employ following the loss of environmental illumination where they …

Using Visual Prompts To Analyze Ejection Fraction In Echocardiograms, Kevin Reisch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Left ventricular ejection fraction (LVEF) is a critical biomarker for heart failure, but manual estimation from echocardiograms is time-consuming. Artificial intelligence can be used to accelerate this process, allowing clinicians to focus on other critical tasks. Current methods typically train models from scratch on echocardiogram datasets; however, this approach is limited by the scarcity of large medical imaging datasets, which are expensive and difficult to acquire. We present a transfer learning approach that leverages pretrained models from massive datasets, enabling continuous improvement as foundation models advance. Our method employs visual prompting to generate trainable masks for echocardiogram videos, transforming the …

Generalizing Medical Image Segmentation Task With Efficient Deep Learning Models, Abel A. Reyes-Angulo

Dissertations, Master's Theses and Master's Reports

Medical Image Segmentation is a critical task in the field of medical imaging, playing a crucial role in diagnostics, treatment planning, and disease monitoring. The emergence of Deep Learning (DL) has ushered in a new era in Artificial Intelligence (AI), propelling remarkable advancements in key domains like language translation, object recognition, and recommendation systems. This evolution has been accompanied by continuous enhancements in computational efficiency and improvements in predictive accuracy. The introduction of sophisticated algorithms, such as convolutional neural networks (CNNs) and transformers, exemplifies these advancements. DL algorithms have demonstrated exceptional efficacy in medical image segmentation tasks, showcasing the potential …

Digital Platform Transitions In The Finance Industry: Three Essays, Cheryll-Ann Wilson

2025

This three-paper dissertation is motivated by an emerging dichotomy in the financial sector: an increasing use of an open-source digital platform—the Python platform—in an industry that historically has been wedded to proprietary systems.

Chapter 1 is a qualitative pilot study to ascertain which factors are likely to motivate investment professionals to select Python versus other tools and/or technologies. I find that efficiency and access to industry-specific libraries—notably Pandas and NumPy—are significant motivators in their selection of Python over Excel. Chapters 2 and 3 examine the issues through a sequential, exploratory mixed methods approach.

Chapter 2—the qualitative field study—investigates how and …

Tiered Coalition Formation Game Variants, Stability, And Simulation, Nathan Arnold

Theses and Dissertations--Computer Science

Tiered coalition formation games (TCFGs) have been proposed for modeling the ordering of power in intransitive structures. Furthering our understanding of the usefulness of this concept requires a close examination of this game and its variants, as well as the delineation between stability concepts and methods of finding stable outcomes. Derived from a simulation of the performance of characters in the games Pokémon Red and Blue Versions, we present an approximation of its power structure found via machine learning. We compare our findings to the community consensus ranking presented on a fan-run website, and further comment on the stability of …

Information-Theoretic Methods For Efficient Training And Robust Evaluations In Self-Supervised Learning, Oscar Skean

Theses and Dissertations--Computer Science

Self-supervised learning (SSL) has become a cornerstone of modern machine learning, offering a scalable alternative to costly human annotation by constructing pretext tasks directly from raw data. While SSL has delivered strong results across vision, language, and multimodal domains, two major limitations persist: (1) SSL methods are often significantly slower to train than supervised counterparts, and (2) evaluation protocols remain narrow, with most studies relying on linear probing accuracy on the pretraining dataset. . These challenges are particularly acute for large language models (LLMs), where training costs and interpretability of intermediate representations are critical concerns.

In this work, we propose …

Predicting Mental Health Disparities Using Machine Learning For African Americans In Southeastern Virginia, Ismail El Moudden, Michael C. Bittner, Matvey V. Karpov, Isaac O. Osunmakinde, Akosua Acheamponmaa, Breshell J. Nevels, Mamadou T. Mbaye, Tonya L. Fields, Karthiga Jordan, Messaoud Bahoura

Department of Obstetrics & Gynecology Faculty Publications

This study examined mental health disparities among African Americans using AI and machine learning for outcome prediction. Analyzing data from African American adults (18–85) in Southeastern Virginia (2016–2020), we found Mood Affective Disorders were most prevalent (41.66%), followed by Schizophrenia Spectrum and Other Psychotic Disorders. Females predominantly experienced mood disorders, with patient ages typically ranging from late thirties to mid-forties. Medicare coverage was notably high among schizophrenia patients, while emergency admissions and comorbidities significantly impacted total healthcare charges. Machine learning models, including gradient boosting, random forest, neural networks, logistic regression, and Naive Bayes, were validated through 100 repeated 5-fold cross-validations. …

Training Set Augmentation And Harmonization Enables Radiomic Models To Detect Early Onset Of Lung Cancer, Claire Huchthausen, Menglin Shi, Gabriel L.A. Sousa, James Larner, Einsley Janowski, Jonathan Colen, Krishni Wijesooriya

Data Science Faculty Publications

Radiomics-based machine learning models have the potential to detect lung cancer at inception from CT scans and transform patient outcomes. Low malignancy rates in early-development pulmonary nodules (PNs) and variable image acquisition hinder development of clinically applicable radiomics-based early detection models. To address these challenges, we augmented training using later-development PNs and harmonized for acquisition effects. We first trained machine learning models to predict PN malignancy using radiomic features from scans of early-development benign and malignant PNs (n = 187) harmonized using ComBat. Observing near-chance performance, we augmented training with later-development benign and malignant PNs (n = 225). We evaluated …

Method Entity And Relation Extraction Based On Automatically Generated Syntactic Templates: A Case Study Of Csdn Artificial Intelligence Blog, Kuiliang Li, Bolin Huang

Journal of Scientific Information Research

[Purpose/significance]There are many relationships between method entities and application scenarios, problems,organizations and other entities. Extracting these entity relationships helps to capture the development trend of technology and promote the improvement of innovation ability.[Method/process]This paper discusses a method for extracting method entities and relations based on automatically generated syntactic templates. By designing a new adaptive template, the method improves flexibility and adaptability, reducing dependence on large-scale labeled data. Using a small number of seed triples, the method iteratively generates syntactic templates and extracts method entities and relations for the CSDN artificial intelligence topic blog. It also improves the extraction quality using …

A Proposed Ehrenfeucht-Fraïssé Game Model For Natural Language Processing Generative Adversarial Networks, Don Li

Anthós

Large Language Models (LLM’s) (e.g., ChatGPT) constitute both a significant research area and commercial application of AI. Current major LLM’s are built on Generative Pre-Trained Transformer (GPT) neural network architecture to perform natural language processing (NLP) tasks. Generative Adversarial Network (GAN) is another popular neural network architecture, which leverages a zero-sum game between constituent neural networks within the architecture to train the GAN, and is widely used for visual data applications. This article proposes a new GAN architecture for NLP: an EF-GAN whose underlying algorithm uses Ehrenfeucht–Fraïssé (EF) games, a game-theoretic approach from model theory to determine elementary equivalence of …

A Happy Medium?: Using Image Generators To Explore Solution-Focused Art Therapy’S Miracle Question, Daniel A. Hernried

Art Therapy | Master's Theses

This mixed methods, randomized, single-session study tested whether integrating text-to-image generations into Solution-Focused Brief Art Therapy alters therapeutic rapport and short-term outcomes relative to traditional artmaking materials. Participants were assigned by coin flip to create using either a text-to-image generator or convention media (23 per group), completing immediate and three-day follow-ups. Alliance was measured using DREAM (Dimensions of Regard, Empathy, and Authenticity Metric), and problems were rated pre/post; groups did not differ significantly on DREAM total or facets, and both modalities produced reliable pre-to-post reductions in problem severity. At the same time, process differences were pronounced: the AI condition showed …

Guiding Evolutionary Algorithms With Large Language Models To Learn Fuzzy Cognitive Maps, Ryan Schuerkamp, Philippe J. Giabbanelli

VMASC Publications

Fuzzy Cognitive Maps (FCMs) are interpretable simulation models that represent causal relationships between concepts as a weighted digraph with labeled nodes. They serve to examine a system’s structure (e.g., what concepts are critical to spreading an intervention’s effects?) and long-term behavior (e.g., if we increase fruit availability, how will its consumption change?). When modelers build FCMs by leveraging participants’ knowledge, the resulting participant-built FCMs can be analyzed and interpreted since participants report perceived causality. However, engaging enough knowledgeable participants to construct an FCM can be challenging. Alternatively, machine learning algorithms derive FCMs from data by selecting relationships to maximize a …

A Spine-Specific Lexicon For The Sentiment Analysis Of Interviews With Adult Spinal Deformity Patients Correlate With Sf-36, Sf-36, And Odi Scores: A Pilot Study Of 25 Patients, Ross Gore, Michael M. Safaee, Christopher J. Lynch, Christopher P. Ames

VMASC Publications

Classic health-related quality of life (HRQOL) metrics are cumbersome, time-intensive, and subject to biases based on the patient’s native language, educational level, and cultural values. Natural language processing (NLP) converts text into quantitative metrics. Sentiment analysis enables subject matter experts to construct domain-specific lexicons that assign a value of either negative (−1) or positive (1) to certain words. The growth of telehealth provides opportunities to apply sentiment analysis to transcripts of adult spinal deformity patients’ visits to derive a novel and less biased HRQOL metric. In this study, we demonstrate the feasibility of constructing a spine-specific lexicon for sentiment analysis …

Quantum-Augmented Ai/Ml For O-Ran: Hierarchical Threat Detection For Synergistic Intelligence And Interpretability, Tan Le, Vanessa Le, Sachin Shetty

VMASC Publications

Open Radio Access Networks (O-RAN) enhance modularity and telemetry granularity but also widen the cybersecurity attack surface across disaggregated control, user and management planes. We propose a hierarchical defense framework with three coordinated layers—anomaly detection, intrusion confirmation, and multiattack classification—each aligned with O-RAN’s telemetry stack. Our approach integrates hybrid quantum computing and machine learning, leveraging amplitude- and entanglement-based feature encodings with deep and ensemble classifiers. We conduct extensive benchmarking across synthetic and real-world telemetry, evaluating encoding depth, architectural variants, and diagnostic fidelity. The framework consistently achieves near-perfect accuracy, high recall, and strong class separability. Multi-faceted evaluation across decision boundaries, probabilistic …

Towards Robust Multimodal Land Use Classification: A Convolutional Embedded Transformer, Muhammad Zia Ur Rehman, Syed Mohammed Shamsul Islam, Anwaar Ulhaq, David Blake, Naeem Janjua

Research outputs 2022 to 2026

Multisource remote sensing data has gained significant attention in land use classification. However, effectively extracting both local and global features from various modalities and fusing them to leverage their complementary information remains a substantial challenge. In this paper, we address this by exploring the use of transformers for simultaneous local and global feature extraction while enabling cross-modality learning to improve the integration of complementary information from HSI and LiDAR data modalities. We propose a spatial feature enhancer module (SFEM) that efficiently captures features across spectral bands while preserving spatial integrity for downstream learning tasks. Building on this, we introduce a …

Genai’S Impact On Global It Management: A Multi-Expert Perspective And Research Agenda, Yogesh K. Dwivedi, Laurie Hughes, Mohammad S. Al-Ahmadi, Vincent Dutot, Syed Q. Ahmed, Shahriar Akter, Rahul De’, Keyao Li, Nitish Singh, Paul Walton

Research outputs 2022 to 2026

Generative AI (GenAI) is disrupting global IT management and challenging established practice. The increasing use of GenAI technology is redefining localization, transforming existing workforce roles, outsourcing strategy, and team dynamics. Simultaneously, GenAI’s security complexities have prompted the rethinking of existing risk frameworks to meet a new set of challenges from GenAI enhanced cyber threats. This article explores these complex and converging factors, providing a roadmap to address GenAI’s significant impact on global IT management. We advocate the responsible adoption of GenAI and importance of building resilient, value-driven, globally consistent IT ecosystems able to adapt to the significant challenges and opportunities …

Gans And Synthetic Financial Data: Calculating Var*, David E. Allen, Leonard Mushunje, Shelton Peiris

Research outputs 2022 to 2026

Generative Adversarial Neural nets (GANs) are a new branch of machine learning techniques. A GAN learns to generate new data from the training data set. We examine the characteristics of the fake financial data using GANs trained on samples of daily S&P 500 and FTSE 100 index values. GANs feature two competing neural networks in a game theoretic context. The Generator net generates pseudo data that is presented to the discriminator net which then attempts to distinguish between the real and the fake data. This facilitates unsupervised learning on the dataset. The generative network generates data sets, while the discriminative …

Ensemble Learning For Mri-Based Brain Tumor Classification: A Weighted Voting Approach, Ha Anh Vu

All Master's Theses

MRI is essential for detecting and diagnosing brain tumors, where accurately distinguishing glioma, meningioma, and pituitary tumors is vital for effective treatment planning. However, tumors' complex morphology and MRI imaging variations present significant challenges for reliable classification. Deep learning models, particularly Convolutional Neural Networks (CNN) and ResNet architectures, have demonstrated impressive performance in medical image analysis but often struggle with generalization across different datasets. On the other hand, traditional classifiers such as Support Vector Machines (SVM) and K-Nearest Neighbors (KNN) leverage handcrafted features like Histogram of Oriented Gradients (HOG), which can effectively capture structural details but may lack the adaptability …

On-Device Recommender Systems: A Comprehensive Survey, Hongzhi Yin, Liang Qu, Tong Chen, Wei Yuan, Ruiqi Zheng, Jing Long, Xin Xia, Yuhui Shi, Chengqi Zhang

Research outputs 2022 to 2026

Recommender systems have been widely deployed in various real-world applications to help users identify content of interest from massive amounts of information. Traditional recommender systems work by collecting user-item interaction data in a cloud-based data center and training a centralized model to perform the recommendation service. However, such cloud-based recommender systems (CloudRSs) inevitably suffer from excessive resource consumption, response latency, as well as privacy and security risks concerning both data and models. Recently, driven by the advances in storage, communication, and computation capabilities of edge devices, there has been a shift of focus from CloudRSs to on-device recommender systems (DeviceRSs), …

Novel Digital Twin Deployment Approaches: Local And Distributed Digital Twin, Shahid Rauf, Fazal Muhammad, Akhtar Badshah, Hisham Alasmary, Muhammad Waqas, Sheng Chen

Research outputs 2022 to 2026

The Digital Twin (DT) technology is considered as a backbone in the Industrial 4.0 revolution as it is playing a vital role in the digitization of various industries. A DT is a virtual representation of a physical entity, thus having the ability to simulate real data generated at physical space to optimize, estimate, control, monitor and forecast states/configurations. Despite enormous benefits, DT technology has several implementation challenges. Although deploying DT on edge or cloud platforms yields a plethora of services, its implementation in both spaces faces certain limitations. These limitations include latency, data communication overload, transmission energy consumption, privacy concerns, …

Panoscu: A Simulation-Based Dataset For Panoramic Indoor Scene Understanding, Mariia Khan, Yue Qiu, Yuren Cong, Jumana Abu-Khalaf, David Suter, Bodo Rosenhahn

Research outputs 2022 to 2026

Panoramic images offer a comprehensive spatial view that is crucial for indoor robotics tasks such as visual room rearrangement, where an agent must restore objects to their original positions or states. Unlike existing 2D scene change understanding datasets, which rely on single-view images, panoramic views capture richer spatial context, object relationships, and occlusions—making them better suited for embodied artificial intelligence (AI) applications. To address this, we introduce Panoramic Scene Change Understanding (PanoSCU), a dataset specifically designed to enhance the visual object rearrangement task. Our dataset comprises 5,300 panoramas generated in an embodied simulator, encompassing 48 common indoor object classes. PanoSCU …

Machine Learning Methods For Intrusion Detection And Response In Network Security, Ayomide Oyemaja

College of Graduate Studies: Theses & Dissertations

Intrusion Detection Systems (IDS) play a crucial role in computer network security by identifying malicious activities and potential cyberattacks. This thesis combines machine learning and cybersecurity by applying Reinforcement Learning (RL) in intrusion detection and response using the NSL-KDD dataset.

We designed and implemented a Q-learning framework where an agent learns to classify network traffic over time by interacting with the environment and receiving rewards based on detection accuracy. We also look at the importance of feature selection and classification techniques and how effective they are in improving model performance, reducing the complexity of computation, and producing more desirable results. …

Evaluating Multimodal Ai Systems: A Comparative Analysis Of Large Languagel Model-Based Models For Text, Image, And Video Generation, Azeezat O. Akinola

College of Graduate Studies: Theses & Dissertations

In the era of rapid technological advancement, efficient content generation, application development, and data management are crucial for meeting the demands of dynamic digital environments. This thesis uses state-of-the-art models to explore three core areas: AI-driven video content creation, text-to-image-to-text consistency, and automatic text summarization. The first study investigates the potential of AI-powered text-to-video generation to democratize video production and enhance storytelling. By comparing the performance of three models—ModelScope, Text2Video (Zero), and Motion Consistency—this study assessed the quality of generated videos using CLIP scores. It evaluated statistical significance through t-tests and homogeneity tests. Results indicate that ModelScope outperformed the others, …

Enhancing Adhd Diagnosis In College Students Using Multimodal Integration Of Nicats And Iva-2 Tools, Rushmila Shabneen

College of Graduate Studies: Theses & Dissertations

This study explores enhanced methods for accurately identifying Attention Deficit Hyperactivity Disorder (ADHD) indicators in college students. ADHD, a neurodevelopmental disorder, impacts attention, impulse control, and emotional regulation, often leading to academic and social difficulties. Many students remain undiagnosed due to symptom overlap with stress and other factors. Traditional tools like the IVA-2 assess behavioral responses but may not fully capture ADHD complexity. This research integrates IVA-2 data with multimodal metrics from the Non-Intrusive Classroom Attention Tracking System (NiCATS), which monitors facial expressions, eye movements, and computer interactions. Preliminary results show that combining these tools improves ADHD detection, reduces false …

Generative Ai And Finding The Law, Paul D. Callister

Faculty Works

Legal information science requires, among other things, principles and theories. The article states six principles or considerations that any discussion of generative AI large language models and their role in finding the law must include. The article concludes that law librarianship will increasingly become legal information science and require new paradigms. In addition to the six principles, the article applies ecological holistic media theory to understand the relationship of the legal community’s cognitive authority, institutions, techné (technology, medium and method), geopolitical factors, and the past and future to understand the changes in this information milieu. The article also explains generative …