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Full-Text Articles in Chemistry

Determination Of The Traits In Leguminous Crops Under Saline Condition, Tojiddin Kuliev, Karomat Ismailova Apr 2021

Determination Of The Traits In Leguminous Crops Under Saline Condition, Tojiddin Kuliev, Karomat Ismailova

Karakalpak Scientific Journal

In this study, the variability and determination of genetic traits for winter legume crop varieties the Vostok-55 (Pisum arvense L) and Mirzachul-1 (Vicia villoza Roth L) were investigated under moderate saline soil condition. Results show that the weight of the bean was marked as variable and highly deterministic, and the height of the plants was the most stable. The selection of plants based on these traits is the most effective way of salinity. Both variety the forage pea Vostok-55 and vetch Mirzachul-1 is highly recommended as a sideration and forage crop in saline lands.


College Of Natural Sciences Newsletter, April 2021, College Of Natural Sciences Apr 2021

College Of Natural Sciences Newsletter, April 2021, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

Volume 2, Issue 4

Page 1 Dean's Message
Page 2 & 3 Awards & Recognition
Page 4 Student Spotlight: Allsion Bjornstad
Page 5 Research Spotlight: Dr. Vondruska & Students
Page 6 Department Head Interviews
Page 7 Media Coverage of CNS
Page 8 Open PRAIRIE Data
Page 9 Student Club Spotlight: BMGSA
Page 10 Then & Now: Urban Geography


Food Security As A Factor Of Sustainable Development Of The Country, Timur Nurimbetov Mar 2021

Food Security As A Factor Of Sustainable Development Of The Country, Timur Nurimbetov

Karakalpak Scientific Journal

The article examines the state of the food market and the trends in ensuring the country’s food security. The article also analyzes the regional characteristics of the agricultural products market in the Republic of Karakalpakstan. The saturation level of regional food markets has been studied. Scientific conclusions and practical recommendations on the supply of food to the population have been made.


Influence Of Laterial State Of Pair Impurity Complex On Recombination Processes In Semiconductors, L Yu Leyderman, R A. Ayukhanov, Abat Uteniyazov, E S. Esenbaeva, Sh X. Annayeva Mar 2021

Influence Of Laterial State Of Pair Impurity Complex On Recombination Processes In Semiconductors, L Yu Leyderman, R A. Ayukhanov, Abat Uteniyazov, E S. Esenbaeva, Sh X. Annayeva

Karakalpak Scientific Journal

The paper analyzes the question of the possible influence of the lateral state of a paired impurity complex on the recombination processes. It is shown that the lateral state of the paired impurity complex does not affect the recombination processes of nonequilibrium carriers - they go through that component of the impurity complex that exchanges carriers with both bands (in this particular case, through the component). The second component of the complex () can apparently play some role in the processes of carrier attachment.


Organization Of Compact Spinning Technology In Textile Clusters, Baxtiyar Aralbaevich Paluanov, Abdimalik Pirmatovich Pirmatov Mar 2021

Organization Of Compact Spinning Technology In Textile Clusters, Baxtiyar Aralbaevich Paluanov, Abdimalik Pirmatovich Pirmatov

Karakalpak Scientific Journal

The article proposes a system of continuous supply of raw cotton in continuous spinning technology and methods of maximizing the preservation of the natural properties of the fiber and obtaining high-quality yarn.


Anticancer And Antiangiogenic Activities Of Alkaloids Isolated From Lantana Camara By Adsorption On The Magnetic Nanoparticles, Hussein Kadhem Al-Hakeim, Rahman Sahib Al-Zabibah, Huda Falah Alzihari, Ali Khudhair Almensoori, Hazim A. Al-Zubaidi, Loiy Elsir Ahmed Hassan Hassan Mar 2021

Anticancer And Antiangiogenic Activities Of Alkaloids Isolated From Lantana Camara By Adsorption On The Magnetic Nanoparticles, Hussein Kadhem Al-Hakeim, Rahman Sahib Al-Zabibah, Huda Falah Alzihari, Ali Khudhair Almensoori, Hazim A. Al-Zubaidi, Loiy Elsir Ahmed Hassan Hassan

Karbala International Journal of Modern Science

Lantana camara L. (L. camara) is a perennial shrub that contains low amounts of alkaloids. In the present study, the magnetic nanoparticles (MNPs) were used to isolate positively charged alkaloids from the methanolic extract of L. camara leaves. The crude alkaloid was fractionated using HPLC to separate the highest peak of the alkaloid fraction (HPAF). The crude alkaloids (CA) and HPAF were tested for their antiproliferative effect against cancer cell lines (MCF-7, HCT-116, and HeLa) and endothelial cells line (EA.hy926) as a standard cell line. Antiangiogenic properties were examined using rat aortic ring assay. …


Mach-Zehnder Quantum Interference Rules In Hydrocarbons With Substituents, Alaa Al-Jobory, Zainelabideen Y. Mijbil Mar 2021

Mach-Zehnder Quantum Interference Rules In Hydrocarbons With Substituents, Alaa Al-Jobory, Zainelabideen Y. Mijbil

Karbala International Journal of Modern Science

We have investigated the conditions of quantum interferences in hydrocarbons with substituents using density functional theory and tight binding approximation combined with non-equilibrium Green’s function technique. The chosen model systems, namely benzene and tripyridyl–triazine molecules, have elucidated three prominent rules. The ‘first rule’ is the occurrence of inevitable, destructive quantum interference when 1,3-benzene ring incorporates single substituent at the fifth site. The ‘second rule’ is the chaotic occurrence of quantum interferences due the position and/or type of the substituents. The ‘third rule’: the substituents decrease (increase) the probability of destructive (constructive) interferences


Physical-Chemical Characterization And Heavy Metals Assessment Of Waters And Sediments Of Sebou Watershed (Top Sebou, Morocco), Mohamed Kabriti, Eda Mahougnon Léonce, Chaimaa Merbouh, Bensaber Abdelfattah, Abdelmajid Achkir, Abdlhakim Aouragh, Iounes Nadia Mar 2021

Physical-Chemical Characterization And Heavy Metals Assessment Of Waters And Sediments Of Sebou Watershed (Top Sebou, Morocco), Mohamed Kabriti, Eda Mahougnon Léonce, Chaimaa Merbouh, Bensaber Abdelfattah, Abdelmajid Achkir, Abdlhakim Aouragh, Iounes Nadia

Karbala International Journal of Modern Science

The main purpose of this study was to investigate the impact of human activities, geochemical background and seasons on pollutant pathway. Surface water, groundwater and sediments were assessed to highlight and confirm those impacts. Sixteen physico-chemical parameters were measured (T°, pH, O2, salinity, conductivity, BOD5, COD, SM, Cl-, NO2-, NO3-, NH4+, TAC, TH, SO₄²- and PO43-) and twelve metallic trace elements were analyzed (Ar, Cr, Zn, Mn, Ni, Fe, Al, Cd, Cu, Pb, K and Na). Five sampling campaigns were carried out in 18 sampling points for over one year, between July 2018 and July 2019 in the upstream part …


Molecular Structure Vibrational & Electronic Properties Of Some Isatin Derivatives, Fatma K. Fkandermili Prof, Fatma M. Aldibashi S, Hakan S. Sayiner Prof Mar 2021

Molecular Structure Vibrational & Electronic Properties Of Some Isatin Derivatives, Fatma K. Fkandermili Prof, Fatma M. Aldibashi S, Hakan S. Sayiner Prof

Karbala International Journal of Modern Science

Abstract

In this study, Natural Bonding Orbitals (NBOs) were applied to isatin, 5‑fluoroisatin, 5‑chloroisatin, 5‑methylisatin and 5‑methoxyisatin using the Lee-Yang-Parr correlation functional B3LYP with 6‑311++G(2d,2p) basis set. Natural bonding analysis was performed to consider the transfer interactions of intra-molecular charge, pre-hybridization and electron density within the isatin, 5‑fluoroisatin, 5‑chloroisatin, 5‑methylisatin and 5‑methoxyisatin. In natural bonding orbital analysis, the wave functions of the electrons were explicated in sets of occupied Lewis type terms, (bonds or lone pairs) and sets of unoccupied non‑Lewis (anti‑bond and Rydberg) localized natural bonding orbitals. The electron density between these orbitals was correlated to stabilize the interaction …


Editorial Board Mar 2021

Editorial Board

Karbala International Journal of Modern Science

No abstract provided.


Neglected Nematodes: The Neurolenin Solution, Kevin M. Shea, Steven Williams Mar 2021

Neglected Nematodes: The Neurolenin Solution, Kevin M. Shea, Steven Williams

Chemistry: Faculty Publications

Over 1 billion people worldwide are affected by Neglected Topical Diseases (NTDs). This group of pathogens encapsulates viruses, bacteria and parasites, and disproportionately affects the world’s poorest and most vulnerable communities in Africa, Asia and Latin America. Lymphatic Filariasis (LF) is an NTD caused by a parasitic nematode infection. The larvae of these filarial nematode worms are transmitted via mosquito bites and disrupt the functioning of the infected individual’s lymphatic system. LF can be caused by three types of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, which are transmitted by the Culex, Anopheles and Aedes mosquito families. Symptomatic …


College Of Natural Sciences Newsletter, March 2021, College Of Natural Sciences Mar 2021

College Of Natural Sciences Newsletter, March 2021, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

Volume 2. Issue 3

Contents:

Page 1 Dean's Message
Page 2-3 Awards and Recognition
Page 4 Student Club Spotlight: MICROBIOLOGY CLUB
Page 5 Research Spotlight: Dr. Chakravarty
Page 6 Open PRAIRIE Data; Grants Awarded in CNS; Research Collquia
Page 7 A Busy Month in Review; Media Coverage of the College


The C. Neoformans Cell Wall: A Scaffold For Virulence, Christine Chrissian Feb 2021

The C. Neoformans Cell Wall: A Scaffold For Virulence, Christine Chrissian

Dissertations, Theses, and Capstone Projects

Cryptococcus neoformans is a globally distributed opportunistic fungal pathogen and the causative agent of life threatening cryptococcal meningoencephalitis in immunocompromised individuals, resulting in ~180,000 deaths each year worldwide. A primary virulence-associated trait of this organism is the production of melanin. Melanins are a class of diverse pigments produced via the oxidation and polymerization of aromatic ring compounds that have a characteristically complex, heterogenous, and amorphous structure. They are synthesized by representatives of all biological kingdoms and share a multitude of remarkable properties such as the ability to absorb ultraviolet (UV) light and protect against ionizing radiation. Melanin production in fungi …


The Effect Of Alcalase Concentration On The Proteins From The Shells Of Litopenaeus Setiferus (White Shrimp), Liam T. Quan Jan 2021

The Effect Of Alcalase Concentration On The Proteins From The Shells Of Litopenaeus Setiferus (White Shrimp), Liam T. Quan

Journal of the South Carolina Academy of Science

Chitin is a naturally abundant polymer that also happens to be biodegradable. Chitin can be used in a variety of different products such as biodegradable plastics, papers, medical products, foods, and medical treatments. To extract chitin, shells must be demineralized and deproteinized. The goal of this experiment was to examine the effect of the protease Alcalase in the deproteinization of litopenaeus setiferus shells. The hypothesis was that if the concentration of Alcalase increased, then the absorbance of proteins in the spectrophotometer reading would increase. The null hypothesis was that if the concentration increased there would be no change in absorption. …


Regulation Of Kv11.1 Isoform Expression By Polyadenylate Binding Protein Nuclear 1, Matthew R. Stump, Rachel T. Nguyen, Rachel H. Drgastin, Delaney Search, Quiming Gong, Zhengfeng Zhou Jan 2021

Regulation Of Kv11.1 Isoform Expression By Polyadenylate Binding Protein Nuclear 1, Matthew R. Stump, Rachel T. Nguyen, Rachel H. Drgastin, Delaney Search, Quiming Gong, Zhengfeng Zhou

Faculty Publications - Department of Biological & Molecular Science

The Kv11.1 voltage-gated potassium channel, encoded by the KCNH2 gene, conducts the rapidly activating delayed rectifier current in the heart. KCNH2 pre-mRNA undergoes alternative polyadenylation to generate two C-terminal Kv11.1 isoforms in the heart. Utilization of a poly(A) signal in exon 15 produces the full-length, functional Kv11.1a isoform, while intron 9 polyadenylation generates the C-terminally truncated, nonfunctional Kv11.1a-USO isoform. The relative expression of Kv11.1a and Kv11.1a-USO isoforms plays an important role in the regulation of Kv11.1 channel function. In this study, we tested the hypothesis that the RNA polyadenylate binding protein nuclear 1 (PABPN1) interacts with a unique 22 nt …


Synthetic Pathways For Potential Platinum 1,10-Phenanthroline Compounds, Jacob Young Jan 2021

Synthetic Pathways For Potential Platinum 1,10-Phenanthroline Compounds, Jacob Young

Mahurin Honors College Capstone Experience/Thesis Projects

There are extremely important uses for platinum when it comes to the treatment of cancers and dementias. One potential therapeutic combines platinum with a structure known as phenanthroline. This platinum phenanthroline structure is normally extremely water-insoluble, rendering it difficult to study and use in biological systems. The Williams’ Biochemistry Laboratory endeavored to find a simpler synthetic pathway for a water-soluble phenanthroline product. While unsuccessful in identifying a product as of yet, many synthetic pathways have been ruled out, and more hypothetical pathways are being formulated for testing.

Among the strategies analyzed are varying solvent, reagents, apparatus, methodology, and temperature in …


Characterization Of Microbial Populations In Landfill Leachate, Umut M. Bicim, Hanna Fulford, Lori A. Hoagland, Alejandro R. Sanchez, Amisha D. Shah, Inez Hua Jan 2021

Characterization Of Microbial Populations In Landfill Leachate, Umut M. Bicim, Hanna Fulford, Lori A. Hoagland, Alejandro R. Sanchez, Amisha D. Shah, Inez Hua

Discovery Undergraduate Interdisciplinary Research Internship

In the United States, municipal solid waste (MSW) landfills remain a potential mining source of recoverable materials, including but not limited to critical, precious, and rare earth metals found in electronic waste. This is possible due to collectible leachate that filters through MSW landfills, carrying metals, nutrients of value, and microbes—some of which may hold key metal bioleaching properties—within. The purpose of this study is to begin analyzing leachate from MSW landfills in the American Midwest to understand the composition of microbial communities within these landfills. Landfill leachate samples sourced in northern Indiana, representing the landfill process during unique times …


College Of Natural Sciences 2021 Year-End Publication, College Of Natural Sciences Jan 2021

College Of Natural Sciences 2021 Year-End Publication, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

Page 2 Welcome, Table of Contents
Page 3 Our Departments: Highlights From 2021
Page 4 Overview of the College
Page 5 Overview of Bold & Blue
Pages 6, 7 Announcing the First Endowed Professorship in the College of Natural Sciences
Page 8 Spooky Science, Astronomy Outreach, SDSU Chemistry Research Features on Journal Cover
Page 9 Students Win Business Plan Competition With Aims to Improve Shelf Life of Produce, Summer Researchers
Page 10 NIH Grant Helps Unravel Rare Inflammatory Genetic Disorders, International Excellence in South Dakota
Page 11 The Next Frontier of Science Education: Virtual Reality, SDSU Researchers Uncover how Cancer …


Identification Of Compounds Causing Cellular Autofluorescence In Touch Samples, Elora C. Wall Jan 2021

Identification Of Compounds Causing Cellular Autofluorescence In Touch Samples, Elora C. Wall

Master of Science in Forensic Science Directed Research Projects

As DNA analysis has advanced and produced tests with higher sensitivities, attention has turned toward obtaining DNA profiles from cells left with fingermarks. Recent studies have reported that cells deposited within fingermarks can exhibit differences in autofluorescence emission in the ‘red’ region of the visible spectrum (e.g., between 650-670 nm), which can be used to differentiate contributor cell population and separate them before DNA profiles. Interestingly, this emission was not consistent to the individual day-to-day and likely not a genetically-controlled attribute of the contributor. Instead, this emission signature results from extended exposure of the skin to certain materials such as …


Editorial Board Dec 2020

Editorial Board

Karbala International Journal of Modern Science

No abstract provided.


Otolith Age Validation And Microchemical Investigation Of The Northern Stock F Atlantic Black Sea Bass (Centropristis Striata), Elise R. Koob Dec 2020

Otolith Age Validation And Microchemical Investigation Of The Northern Stock F Atlantic Black Sea Bass (Centropristis Striata), Elise R. Koob

Graduate Masters Theses

Black sea bass (Centropristis striata) is a demersal marine species that supports extensive commercial and recreational fisheries along the Atlantic coast. A recent expansion into the Gulf of Maine raises questions about this species’ movement and population dynamics in the region. Additionally, the 2016 catch-at-age stock assessment model for the northern stock incorporated a population split at the Hudson Canyon. Though this model better accounts for differences in populations, several issues remain. First, validation of the otolith ageing technique for this stock is incomplete; and, second, the origin of fish that moved into the northern ranges of the Gulf of …


Microbiological, Physicochemical, And Immunological Analysis Of A Commercial Cashew Nut-Based Yogurt, Christopher P. Mattison, Kayanush Aryana, Kristen Clermont, Eric Prestenburg, Steven W. Lloyd, Casey .. Grimm, Richard L. Wasserman Nov 2020

Microbiological, Physicochemical, And Immunological Analysis Of A Commercial Cashew Nut-Based Yogurt, Christopher P. Mattison, Kayanush Aryana, Kristen Clermont, Eric Prestenburg, Steven W. Lloyd, Casey .. Grimm, Richard L. Wasserman

Faculty Publications

Nut-based milks and yogurts are gaining popularity, but may not offer the same benefits as dairy yogurts to consumers. Cashew nuts often cause severe allergic reactions, and cashew nut allergens are stable to several types of processing. To compare its characteristics to dairy yogurt and characterize the effects of fermentation on the Ana o 1-3 cashew nut allergens, a commercial yogurt made from cashew nuts (Cashewgurt) was evaluated for microbiological, physiochemical, and immunological properties. Average counts for lactobacilli and Streptococcus thermophilus were greater than 10 million colony forming units per milliliter, indicating the capacity to provide a health benefit. Cashewgurt …


Population Genetics Of Rhizophora Apiculata In Peninsular Malaysia Using Microsatellite Markers, Amelia Azman Oct 2020

Population Genetics Of Rhizophora Apiculata In Peninsular Malaysia Using Microsatellite Markers, Amelia Azman

Student Works (2020-2029)

Rampant illegal logging, overharvesting and deforestation coupled with climate change, pose significant threats to the natural stands of Rhizophora apiculata, or locally known as Bakau Minyak; one of the most economically and ecologically important species of mangroves in Peninsular Malaysia. Despite being a dominant mangrove species, the reduction in the number of R. apiculata in its habitat has resulted in concerns over the long-term survival potential of the species. In Malaysia, genetic information to develop effective guidelines for the conservation and management of mangrove species has been lacking, and hence, further research should be conducted to fill this gap. The …


A Fuzzy Assessment Model For Hospitals Services Quality Based On Patient Experience, Mohamed Khodyer Alkafaji, Eman Salih Al-Shamery Oct 2020

A Fuzzy Assessment Model For Hospitals Services Quality Based On Patient Experience, Mohamed Khodyer Alkafaji, Eman Salih Al-Shamery

Karbala International Journal of Modern Science

The patient's experience is a lens for services assessment that provide from healthcare institutions because the patient is the first and the last recipient for the service. The patient's experience carries a lot of uncertainty and an ultimate decision cannot be taken from the patient about the services, but it carries the partial truth. Many artificial intelligence technologies deal with the concept of partial truth, such as genetic algorithms and neural networks, but the fuzzy logic remains pioneering to deal with uncertainty. This paper aims to develop an assessment model by using fuzzy inference that is able to assess the …


A Systematic Mapping Study On The Risk Factors Leading To Type Ii Diabetes Mellitus, Karar N. J Musafer, Fahrul Zaman Huyop, Mufeed J Ewadh, Eko Supriyanto, Mohammad Rava Oct 2020

A Systematic Mapping Study On The Risk Factors Leading To Type Ii Diabetes Mellitus, Karar N. J Musafer, Fahrul Zaman Huyop, Mufeed J Ewadh, Eko Supriyanto, Mohammad Rava

Karbala International Journal of Modern Science

Diabetes is one of the most common diseases that has had devastating effects on the general population. It is also among the most popular research trends in modern medicine. Thus, due to the complexity and desirability of this particular affliction, there is a lot of demand towards understanding this disease better, so that it can pave the way towards better solutions in combating diabetes. The aim of this review is to provide a categorization of the risk factors leading to Type II Diabetes. In order to provide a justification for the type of diabetes, an explanation is provided which covers …


Chemical Composition And Antibacterial Activity Of The Essential Oil Of Myrtus Communis Leaves, Hajar El Hartiti, Amine El Mostaphi, Mariam Barrahi, Aouatif Ben Ali, Nabila Chahboun, Rajaa Amiyare, Abdelkader Zarrouk, Brahim Bourkhiss, Mohammed Ouhssine Oct 2020

Chemical Composition And Antibacterial Activity Of The Essential Oil Of Myrtus Communis Leaves, Hajar El Hartiti, Amine El Mostaphi, Mariam Barrahi, Aouatif Ben Ali, Nabila Chahboun, Rajaa Amiyare, Abdelkader Zarrouk, Brahim Bourkhiss, Mohammed Ouhssine

Karbala International Journal of Modern Science

The aim of this work is to determine the yield of the essential oil of the Myrtus communis leaves, to identify its chemical composition and to evaluate its antibacterial properties. The plant is harvested from Sidi Ahmed Chrif, a region in Ouazzane, Morocco. The extraction of the essential oil was carried out by hydrodistillation in a Clevenger apparatus type. The average yield was 0.7%. The analysis of this oil by Gas Chromatography coupled with Mass Spectrum (GC/MS) allows the identification of 32 compounds. Eucalyptol was the main compound with 42.43%, followed by myrtenyl acetate (21.25%) and α-pinene (19.39%). Myrtle essential …


Hormones Of Maize Crop As Affected By Potassium Fertilization , Water Quality And Ascobin Foliar Application ., Qais Hussain Al-Samak Prof., Fatima Karim Khudair Alasadi Oct 2020

Hormones Of Maize Crop As Affected By Potassium Fertilization , Water Quality And Ascobin Foliar Application ., Qais Hussain Al-Samak Prof., Fatima Karim Khudair Alasadi

Karbala International Journal of Modern Science

A pot assay on the plastic container of the wire sunshade in the University of Kerbala's Agricultural Division was conducted to research the impact of potassium treatment, the salinity of irrigation water and ascobin sprinkling, just as their connections, on the some plant hormones activities (auxin, gibberellin and abscisic acid) in developing Zea mays crops in a soil with sandy texture during the farming fall period of 2017–2018. The trial was planned as a factorial one with three factors, Potassium adding are 0, 100 and 200 Kg K.ha–1 . the irrigation water salinity are 1, 3 and 6 ds.m …


Editorial Board Oct 2020

Editorial Board

Karbala International Journal of Modern Science

No abstract provided.


All-Atomic Molecular Dynamic Studies Of Human And Drosophila Cdk8: Insights Into Their Kinase Domains, The Lxxll Motifs, And Drug Binding Site, Wu Xu, Xiao-Jun Xie, Ali K. Faust, Mengmeng Liu, Xiao Li, Feng Chen, Ashlin A. Naquin, Avery C. Walton, Peter W. Kishbaugh, Jun-Yuan Ji Oct 2020

All-Atomic Molecular Dynamic Studies Of Human And Drosophila Cdk8: Insights Into Their Kinase Domains, The Lxxll Motifs, And Drug Binding Site, Wu Xu, Xiao-Jun Xie, Ali K. Faust, Mengmeng Liu, Xiao Li, Feng Chen, Ashlin A. Naquin, Avery C. Walton, Peter W. Kishbaugh, Jun-Yuan Ji

Faculty Publications

Cyclin-dependent kinase 8 (CDK8) and its regulatory partner Cyclin C (CycC) play conserved roles in modulating RNA polymerase II (Pol II)-dependent gene expression. To understand the structure and function relations of CDK8, we analyzed the structures of human and Drosophila CDK8 proteins using molecular dynamics simulations, combined with functional analyses in Drosophila. Specifically, we evaluated the structural differences between hCDK8 and dCDK8 to predict the effects of the LXXLL motif mutation (AQKAA), the P154L mutations, and drug binding on local structures of the CDK8 proteins. First, we have observed that both the LXXLL motif and the kinase activity of CDK8 …


A Review Of The Preclinical And Clinical Efficacy Of Remdesivir, Hydroxychloroquine, And Lopinavir-Ritonavir Treatments Against Covid-19, Dawid Maciorowski, Samir Z. El Idrissi, Yash Gupta, Brian J. Medernach, Michael B. Burns, Daniel P. Becker Ph.D., Ravi Durvasula, Prakasha Kempaiah Sep 2020

A Review Of The Preclinical And Clinical Efficacy Of Remdesivir, Hydroxychloroquine, And Lopinavir-Ritonavir Treatments Against Covid-19, Dawid Maciorowski, Samir Z. El Idrissi, Yash Gupta, Brian J. Medernach, Michael B. Burns, Daniel P. Becker Ph.D., Ravi Durvasula, Prakasha Kempaiah

Chemistry: Faculty Publications and Other Works

In December of 2019, an outbreak of a novel coronavirus flared in Wuhan, the capital city of the Hubei Province, China. The pathogen has been identified as a novel enveloped RNA beta-coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus SARS-CoV-2 is associated with a disease characterized by severe atypical pneumonia known as coronavirus 2019 (COVID-19). Typical symptoms of this disease include cough, fever, malaise, shortness of breath, gastrointestinal symptoms, anosmia, and, in severe cases, pneumonia.1 The high-risk group of COVID-19 patients includes people over the age of 60 years as well as people with existing cardiovascular …