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Articles 181 - 210 of 18216
Full-Text Articles in Physical Sciences and Mathematics
Determination Of Total Ammonia Nitrogen By Gas-Diffusion Flow Injection Analysis (Gd-Fia)-Spectrophotometry Using Minnieroot Flower (Ruellia Tuberosa) As Natural Reagent, Lani Artana Putri, Puspita Mufidah Sari, Hermin Sulistyarti, Akhmad Sabarudin, Erwin Sulistyo
Determination Of Total Ammonia Nitrogen By Gas-Diffusion Flow Injection Analysis (Gd-Fia)-Spectrophotometry Using Minnieroot Flower (Ruellia Tuberosa) As Natural Reagent, Lani Artana Putri, Puspita Mufidah Sari, Hermin Sulistyarti, Akhmad Sabarudin, Erwin Sulistyo
Makara Journal of Science
Total ammonia nitrogen (TAN) is a pollutant agent found in water and generated from the metabolisms of living organisms and the decomposition of organic matter. This research aims to develop an efficient, low-cost, and environmentally friendly TAN analysis method. The principle of this method is based on the reaction of TAN injected in the donor stream with NaOH to form alkaline gaseous ammonia. The gaseous ammonia diffuses through a hydrophobic membrane into an acceptor stream containing Ruellia tuberosa extract. The presence of NH3 gas in the acceptor stream changes the extract color from pinkish to green, which is monitored …
Relative Importance Of Radar Variables For Nowcasting Heavy Rainfall: A Machine Learning Approach, Yi Victor Wang, Seung Hee Kim, Geunsu Lyu, Choeng-Lyong Lee, Gyuwon Lee, Ki-Hong Min, Menas C. Kafatos
Relative Importance Of Radar Variables For Nowcasting Heavy Rainfall: A Machine Learning Approach, Yi Victor Wang, Seung Hee Kim, Geunsu Lyu, Choeng-Lyong Lee, Gyuwon Lee, Ki-Hong Min, Menas C. Kafatos
Institute for ECHO Articles and Research
Highly short-term forecasting, or nowcasting, of heavy rainfall due to rapidly evolving mesoscale convective systems (MCSs) is particularly challenging for traditional numerical weather prediction models. To overcome such a challenge, a growing number of studies have shown significant advantages of using machine learning (ML) modeling techniques with remote sensing data, especially weather radar data, for high-resolution rainfall nowcasting. To improve ML model performance, it is essential first and foremost to quantify the importance of radar variables and identify pertinent predictors of rainfall that can also be associated with domain knowledge. In this study, a set of MCS types consisting of …
Digital Technology Enables Construction Of National Governance Modernization, Yue Hao, Kaihua Chen, Jin Kang, Xiaoguang Yang, Chao Zhang, Xiaolong Zheng
Digital Technology Enables Construction Of National Governance Modernization, Yue Hao, Kaihua Chen, Jin Kang, Xiaoguang Yang, Chao Zhang, Xiaolong Zheng
Bulletin of Chinese Academy of Sciences (Chinese Version)
As digital technologies continue to be integrated into the whole process of economic and social development, promoting the modernization of digital technology-enabled national governance systems and capabilities has become an important way to seize the strategic initiative in the future world competitive landscape, and has attracted the attention of countries around the world. The rapid development of digital technologies such as big data collection, storage, processing, and analysis is constantly optimizing the organizational system structure of national governance, upgrading and perfecting the quality and methods of national governance personnel, and accelerating the process of making national governance efficient, scientific, intelligent …
Challenges And Measurements For Governance Of Modern Cyber Space Society, Pinghui Wang, Hongbin Pei, Junzhou Zhao, Tao Qin, Chao Shen, Dongliang Liu, Xiaohong Guan
Challenges And Measurements For Governance Of Modern Cyber Space Society, Pinghui Wang, Hongbin Pei, Junzhou Zhao, Tao Qin, Chao Shen, Dongliang Liu, Xiaohong Guan
Bulletin of Chinese Academy of Sciences (Chinese Version)
The rapid development of information technology has unprecedentedly created a prosperous cyber society and greatly enhanced productivity facilitated by social interaction. At the same time, many problems emerge in the cyber society, such as telecom fraud, privacy leakage, Internet pollution, and algorithmic discrimination. The problems bring new challenges to social order and security. In order to find the way of cyber society governance and promote the modernization of national governance, this paper first presents the analyses on the new problems encountered in the cyber society in three typical scenarios, i.e., identity governance, behavior governance, and algorithm governance, as well as …
Deepening Digital Technologies To Enable Modernization Of China’S Governance Of Health, Tara Qia Sun, Xia Feng, Yuntao Long, Zongben Xu
Deepening Digital Technologies To Enable Modernization Of China’S Governance Of Health, Tara Qia Sun, Xia Feng, Yuntao Long, Zongben Xu
Bulletin of Chinese Academy of Sciences (Chinese Version)
One significant goal of science and technology innovation is to set our sights on the health and safety of the people. The rapid development of digital technologies provides multiple potentials and path to achieve the modernization of China's health governance. the role of digital technologies on enabling multiple stakeholders (i.e., hospitals, doctors, government, and social groups) to improve the supply capacity, the inclusiveness, fairness, friendliness, and convenience of health service. Second, we explore the four key issues of using digital technologies to enable the governance of health construction of digital health infrastructures, the factors affecting the adoption of digital technologies, …
Strategic Perspective Of Leveraging New Generation Information Technology To Enable Modernization Of Emergency Management, Haibo Zhang, Xinyu Dai, Depei Qian, Jian Lyu
Strategic Perspective Of Leveraging New Generation Information Technology To Enable Modernization Of Emergency Management, Haibo Zhang, Xinyu Dai, Depei Qian, Jian Lyu
Bulletin of Chinese Academy of Sciences (Chinese Version)
The application and development of the new generation information technology is a vital support to realize the modernization of emergency management. At present, the new generation information technology such as big data and artificial intelligence has been widely used in natural disasters, safe production, and other fields. It has improved the monitoring and early warning, regulation and law enforcement, command and decision support, rescue, and social mobilization capabilities of governments, promoted the level of intrinsic safety of enterprises, provided important support for the precise prevention and control of the COVID-19, and increased the efficiency of China’s emergency management and sense …
Digital Technology Enables Modernization Of National Statistics, Zongben Xu, Yanyun Zhao, Liping Zhu, Guang Chen, Hongyun Zhang
Digital Technology Enables Modernization Of National Statistics, Zongben Xu, Yanyun Zhao, Liping Zhu, Guang Chen, Hongyun Zhang
Bulletin of Chinese Academy of Sciences (Chinese Version)
The modernization of national statistics is part of the modernization of national governance. Digital technology has provided power for the transformation of statistical production mode, the improvement of statistical productivity, and the reconstruction of statistical production relations. Digital technology has become an important prerequisite for the promotion of statistical modernization reform. This study summarizes the international experience of digital technology enabling government statistics, the top-level design of national statistical legal system, and the importance of digital technology in promoting the modernization of statistics. This study also analyzes the main challenges existing in the current national statistics and data work. Finally, …
Compatibility Of Crude Oil Blends─Processing Issues Related To Asphaltene Precipitation, Methods Of Instability Prediction─A Review, Krzysztof Bambinek, Andrzej Przyjazny, Grzegorz Boczkaj
Compatibility Of Crude Oil Blends─Processing Issues Related To Asphaltene Precipitation, Methods Of Instability Prediction─A Review, Krzysztof Bambinek, Andrzej Przyjazny, Grzegorz Boczkaj
Natural Sciences Publications
Processing crude oil of variable composition, especially due to the need to process crude oil blends obtained from various sources, presents a tremendous process challenge. This is mainly due to the destabilization of the colloidal system manifested mostly by the precipitation of the asphaltene fraction. The precipitation of asphaltenes from crude oil is a serious problem during extraction, transport, and processing. In the latter case, engineers and scientists have spent a lot of time determining what mechanisms are conducive to the occurrence of this phenomenon. On the one hand, there was a scientific curiosity about the principles of the nanoworld …
Creating Data From Unstructured Text With Context Rule Assisted Machine Learning (Craml), Stephen Meisenbacher, Peter Norlander
Creating Data From Unstructured Text With Context Rule Assisted Machine Learning (Craml), Stephen Meisenbacher, Peter Norlander
School of Business: Faculty Publications and Other Works
Popular approaches to building data from unstructured text come with limitations, such as scalability, interpretability, replicability, and real-world applicability. These can be overcome with Context Rule Assisted Machine Learning (CRAML), a method and no-code suite of software tools that builds structured, labeled datasets which are accurate and reproducible. CRAML enables domain experts to access uncommon constructs within a document corpus in a low-resource, transparent, and flexible manner. CRAML produces document-level datasets for quantitative research and makes qualitative classification schemes scalable over large volumes of text. We demonstrate that the method is useful for bibliographic analysis, transparent analysis of proprietary data, …
Phase I Activities Of The Earth Mapping Resources Initiative (Earth Mri) In The Western Kentucky Fluorspar District, Georgina Lukoczki, Craig Dietsch, John B. Hickman, Emily Morris, Douglas C. Curl, Carrie Pulliam, Stephanie Vicroy, William M. Andrews Jr.
Phase I Activities Of The Earth Mapping Resources Initiative (Earth Mri) In The Western Kentucky Fluorspar District, Georgina Lukoczki, Craig Dietsch, John B. Hickman, Emily Morris, Douglas C. Curl, Carrie Pulliam, Stephanie Vicroy, William M. Andrews Jr.
Report of Investigations--KGS
The Western Kentucky Fluorspar District (WKFD), which comprises the Kentucky portion of the Illinois–Kentucky Fluorspar District, is well known for the occurrence of strategically important critical mineral resources, such as fluorite (fluorspar) and rare earth elements (REEs). Due to technological advances, demand has increased for critical minerals used in cell phones, magnets in wind turbines, batteries for electric vehicles, smart weapons, and other devices and systems. The overall objective of the Earth Mapping Resources Initiative (Earth MRI) program, directed by the U.S. Geological Survey (USGS), is to gather information that will help better understand the distribution of critical minerals in …
Cenozoic Extension Of The Lake Tanganyika Rift, East Africa: Structures, Tectonostratigraphy And Paleoenvironmental Reconstruction, Shaidu Shaban
Cenozoic Extension Of The Lake Tanganyika Rift, East Africa: Structures, Tectonostratigraphy And Paleoenvironmental Reconstruction, Shaidu Shaban
Dissertations - ALL
Active continental rifts are ideal sites for understanding the break-up of continents, and long-lived rift lake environments are known as important reservoirs for endemic communities and biodiversity. The sedimentary fill of extensional continental rifts within the East Africa Rift System (EARS) records a long history of continental extension and variable tropical climate that is unparalleled in its duration and fidelity. Continental extensional basins are sensitive to variations caused by the interplay between tectonics, sedimentary processes, and climate change. However, to discern the sedimentary fill history and its related tectonostratigraphy, as well as for reconstructing past climate changes, high-fidelity data such …
A Coherence-Colored Look Inside Reverse Micelles: Advancing Magnetic Resonance Relaxometry To Characterize Internal Water Pool Dynamics, Alec Beaton
Dissertations - ALL
Traditional data acquisition methods in Nuclear Magnetic Resonance (NMR) collect a subset of the total amount of generated data and discard the rest. In this work, a modified approach toward NMR data acquisition and analysis is formalized and applied in a series of different contexts, ultimately illustrating the utility of collecting and considering this traditionally discarded data. In particular, it is shown that this approach both facilitates and improves NMR data acquisition capabilities at low field (15 MHz), enabling one to overcome challenges arising from, for example, fluctuations in the static magnetic field.With these developments in hand, the dual resonance …
The Unexpected Effectiveness Of Strategically Sparse Cooperation, Neal D. Munson
The Unexpected Effectiveness Of Strategically Sparse Cooperation, Neal D. Munson
Theses and Dissertations
In this work, we will show a result derived from a class of economically inspired multi-agent differential games. The result shows that in the class of games we present, only a sparse cooperation structure is needed by the agents to achieve an outcome that is in a particular sense "optimal". One may expect that to achieve such an outcome, a centralized control or full cooperation would be necessary; it is not. Not only is it not necessary - it is never necessary. We precisely characterize what kind of cooperation IS necessary to attain that kind of optimality. Only the sparsest …
Hamilton Cycles In Bidirected Complete Graphs, Arthur Busch, Mohammed A. Mutar, Daniel Slilaty
Hamilton Cycles In Bidirected Complete Graphs, Arthur Busch, Mohammed A. Mutar, Daniel Slilaty
Mathematics and Statistics Faculty Publications
Zaslavsky observed that the topics of directed cycles in directed graphs and alternating cycles in edge 2-colored graphs have a common generalization in the study of coherent cycles in bidirected graphs. There are classical theorems by Camion, Harary and Moser, Häggkvist and Manoussakis, and Saad which relate strong connectivity and Hamiltonicity in directed "complete" graphs and edge 2-colored "complete" graphs. We prove two analogues to these theorems for bidirected "complete" signed graphs.
Golay Codes And Quantum Contextuality, Mordecai Waegell, P. K. Aravind
Golay Codes And Quantum Contextuality, Mordecai Waegell, P. K. Aravind
Mathematics, Physics, and Computer Science Faculty Articles and Research
It is shown that the codewords of the binary and ternary Golay codes can be converted into rays in RP23 and RP11 that provide proofs of the Kochen-Specker theorem in real state spaces of dimensions 24 and 12, respectively. Some implications of these results are discussed.
Short-Range Magnetic Correlations, Spontaneous Magnetovolume Effect, And Local Distortion In Magnetic Semiconductor Mnte, Raju Baral
Theses and Dissertations
The antiferromagnetic semiconductor MnTe has recently attracted significant interest as a potential high-performance thermoelectric material. Its promising thermoelectric properties are due in large part to short-range magnetic correlations in the paramagnetic state, which enhance the thermopower through the paramagnon drag effect. Using magnetic pair distribution function (mPDF) analysis of neutron total scattering data, we present a detailed, real-space picture of the short-range magnetic correlation in MnTe, offering a deeper view into the paramagnon drag effect and the nature of the correlated paramagnetic state. We confirm the presence of nanometer-scale antiferromagnetic correlations far into the paramagnetic state, show the evolution of …
Association Of Chlorhexidine Use And Scaling And Root Planing With Birth Outcomes In Pregnant Individuals With Periodontitis: A Systematic Review And Meta-Analysis, Maxwell Akonde, Rajat Das Gupta, Maxwell Akonde, Mark Reynolds, Stephanie Smith-Warner, Jihong Liu Sc.D., Fouzia Tarannum, James Beck, Donald Mattison
Association Of Chlorhexidine Use And Scaling And Root Planing With Birth Outcomes In Pregnant Individuals With Periodontitis: A Systematic Review And Meta-Analysis, Maxwell Akonde, Rajat Das Gupta, Maxwell Akonde, Mark Reynolds, Stephanie Smith-Warner, Jihong Liu Sc.D., Fouzia Tarannum, James Beck, Donald Mattison
Faculty Publications
Importance Chlorhexidine mouthwash enhances treatment effects of conventional periodontal treatment, but data on chlorhexidine as a source of heterogeneity in meta-analyses assessing the treatment of maternal periodontitis in association with birth outcomes are lacking.
Objective To assess possible heterogeneity by chlorhexidine use in randomized clinical trials (RCTs) evaluating the effect of periodontal treatment (ie, scaling and root planing [SRP]) vs no treatment on birth outcomes.
Data Sources Cochrane Oral Health’s Trials Register, Cochrane Pregnancy and Childbirth’s Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE Ovid, Embase Ovid, LILACS BIREME Virtual Health Library (Latin American and Caribbean Health Science …
Association Of Chlorhexidine Use And Scaling And Root Planing With Birth Outcomes In Pregnant Individuals With Periodontitis: A Systematic Review And Meta-Analysis, Anwar T. Nerchant, Rajat Das Gupta, Maxwell Akonde, Mark Reynolds, Stephanie Smith-Warner, Jihong Liu, Fouzia Tarannum, James Beck, Donald Mattison
Association Of Chlorhexidine Use And Scaling And Root Planing With Birth Outcomes In Pregnant Individuals With Periodontitis: A Systematic Review And Meta-Analysis, Anwar T. Nerchant, Rajat Das Gupta, Maxwell Akonde, Mark Reynolds, Stephanie Smith-Warner, Jihong Liu, Fouzia Tarannum, James Beck, Donald Mattison
Faculty Publications
Importance Chlorhexidine mouthwash enhances treatment effects of conventional periodontal treatment, but data on chlorhexidine as a source of heterogeneity in meta-analyses assessing the treatment of maternal periodontitis in association with birth outcomes are lacking.
Objective To assess possible heterogeneity by chlorhexidine use in randomized clinical trials (RCTs) evaluating the effect of periodontal treatment (ie, scaling and root planing [SRP]) vs no treatment on birth outcomes.
Data Sources Cochrane Oral Health’s Trials Register, Cochrane Pregnancy and Childbirth’s Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE Ovid, Embase Ovid, LILACS BIREME Virtual Health Library (Latin American and Caribbean Health Science …
Hybrid Life Cycles In Software Development, Eric Vincent Schoenborn
Hybrid Life Cycles In Software Development, Eric Vincent Schoenborn
Masters Projects
This project applied software specification gathering, architecture, work planning, and development to a real-world development effort for a local business. This project began with a feasibility meeting with the owner of Zeal Aerial Fitness. After feasibility was assessed the intended users, needed functionality, and expected user restrictions were identified with the stakeholders. A hybrid software lifecycle was selected to allow a focus on base functionality up front followed by an iterative development of expectations of the stakeholders. I was able to create various specification diagrams that express the end projects goals to both developers and non-tech individuals using a standard …
Application Of Distributed Fiber-Optic Sensing For Pressure Predictions And Multiphase Flow Characterization, Gerald Kelechi Ekechukwu
Application Of Distributed Fiber-Optic Sensing For Pressure Predictions And Multiphase Flow Characterization, Gerald Kelechi Ekechukwu
LSU Doctoral Dissertations
In the oil and gas industry, distributed fiber optics sensing (DFOS) has the potential to revolutionize well and reservoir surveillance applications. Using fiber optic sensors is becoming increasingly common because of its chemically passive and non-magnetic interference properties, the possibility of flexible installations that could be behind the casing, on the tubing, or run on wireline, as well as the potential for densely distributed measurements along the entire length of the fiber. The main objectives of my research are to develop and demonstrate novel signal processing and machine learning computational techniques and workflows on DFOS data for a variety of …
Defining Traffic Scenarios For The Visually Impaired, Judith Jakob, Kordula Kugele, József Tick
Defining Traffic Scenarios For The Visually Impaired, Judith Jakob, Kordula Kugele, József Tick
The Qualitative Report
For the development of a transfer concept of camera-based object detections from Advanced Driver Assistance Systems to the assistance of the visually impaired, we define relevant traffic scenarios and vision use cases by means of problem-centered interviews with four experts and ten members of the target group. We identify the six traffic scenarios: general orientation, navigating to an address, crossing a road, obstacle avoidance, boarding a bus, and at the train station clustered into the three categories: Orientation, Pedestrian, and Public Transport. Based on the data, we describe each traffic scenario and derive a summarizing table adapted from software engineering …
Pariette Wetlands Water, Sediment And Plant Total Selenium Concentration, Colleen P. Jones, Paul R. Grossl, Astrid R. Jacobson
Pariette Wetlands Water, Sediment And Plant Total Selenium Concentration, Colleen P. Jones, Paul R. Grossl, Astrid R. Jacobson
Browse all Datasets
We measured total Selenium in plants from July through November of 2012 and in water, macroinvertebrates, plants, and sediments from July of 2014 from Pariette Wetlands, Utah, U.S.A. to test for spatial, temporal, plant species and plant tissue distribution of Selenium.
Metallacycle-Mediated Cross-Coupling As An Enabling Tool For Studies In Carbocycle Synthesis And Functionalization, Adam Barry Millham
Metallacycle-Mediated Cross-Coupling As An Enabling Tool For Studies In Carbocycle Synthesis And Functionalization, Adam Barry Millham
Dartmouth College Ph.D Dissertations
Natural products, specifically complex, carbocyclic natural products, have served as the inspiration for novel methods development for decades. Over that time, metallacycle-mediated cross-coupling has arisen as a powerful means for the synthesis of fused carbocycles. This work details three methods for the synthesis and functionalization of carbocyclic motifs that have been enabled by Ti-mediated cross-coupling reactions. The first of these studies include a complementary method to the Pauson–Khand reaction for the synthesis of highly substituted cyclopentenones via Ti-mediated alkyne–β-ketoester coupling. The second project, a modern approach to steroidal tetracycles, will be discussed that features: (1) an alkoxide-directed metallacycle-mediated [2+2+2] annulation …
Arginine Methylation Of The Pgc-1Α C‑Terminus Is Temperature- Dependent, Meryl Mendoz, Mariel Mendoza, Tiffany Lubrino, Sidney Briski, Immaculeta Osuji, Janielle Cuala, Brendan Ly, Ivan Ocegueda, Harvey Peralta, Benjamin A. Garcia, Cecilia Zurita-Lopez
Arginine Methylation Of The Pgc-1Α C‑Terminus Is Temperature- Dependent, Meryl Mendoz, Mariel Mendoza, Tiffany Lubrino, Sidney Briski, Immaculeta Osuji, Janielle Cuala, Brendan Ly, Ivan Ocegueda, Harvey Peralta, Benjamin A. Garcia, Cecilia Zurita-Lopez
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
We set out to determine whether the C-terminus (amino acids 481–798) of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α, UniProt Q9UBK2), a regulatory metabolic protein involved in mitochondrial biogenesis, and respiration, is an arginine methyltransferase substrate. Arginine methylation by protein arginine methyltransferases (PRMTs) alters protein function and thus contributes to various cellular processes. In addition to confirming methylation of the C-terminus by PRMT1 as described in the literature, we have identified methylation by another member of the PRMT family, PRMT7. We performed in vitro methylation reactions using recombinant mammalian PRMT7 and PRMT1 at 37, 30, 21, 18, and 4 °C. …
A Causal-Comparative Study Of The Impact Of Meaningful Watershed Environmental Experiences On The Academic Achievement Of Middle School Students, Gina R. Mason
Doctoral Dissertations and Projects
Meaningful watershed educational experiences (MWEE) are student-centered, problem solving-oriented environmental educational experiences in which students investigate local environmental issues leading to civic engagement and informed action. The four components of an MWEE include issue definition, outdoor field experience, synthesis and conclusion, and action projects. While multiple benefits have been shown to be gained through participation in environmental education, this study’s aim was to observe the impact MWEEs have on academic achievement in middle school students. This quantitative, ex post facto, causal-comparative study examined the impact MWEEs had on students’ achievement scores, as measured by Pennsylvania System of School Assessment (PSSA) …
Effect Of Temperature And Sodium Chloride Addition On The Conductivity Of Sodium (Polystyrene Sulfonate) Aqueous Solutions, Saida Asfour, Ahmed Ayyad, Fahed Takrori
Effect Of Temperature And Sodium Chloride Addition On The Conductivity Of Sodium (Polystyrene Sulfonate) Aqueous Solutions, Saida Asfour, Ahmed Ayyad, Fahed Takrori
Hebron University Research Journal-A (Natural Sciences) - (مجلة جامعة الخليل للبحوث- أ (العلوم الطبيعيه
The conductivity of sodium (polystyrene sulfonate) (NaPSS) aqueous solutions as a function of NaPSS concentration 0.15 g – 2.0 g NaPSS in 100 mL of distilled water, sodium chloride concentration (NaCl) in the range of 0.1 M - 0.4 M and in temperature range of 278 K – 328 K have been studied. The study found that conductivity increases with increasing NaPSS concentration both in pure water and in salt solution. It is also found that conductivity increases with increasing either NaCl concentration or temperature. The interesting finding here is that additivity rule, that the conductivity of the polyelectrolyte kps …
Post-Translational Modifications Of Cyclophilin D Fine-Tune Its Conformational Dynamics And Activity: Implications For Its Mitochondrial Function, Jacques Kumutima, Xin-Qiu Joe Yao, Donald Hamelberg
Post-Translational Modifications Of Cyclophilin D Fine-Tune Its Conformational Dynamics And Activity: Implications For Its Mitochondrial Function, Jacques Kumutima, Xin-Qiu Joe Yao, Donald Hamelberg
Chemistry Faculty Publications
Mitochondria are the powerhouse of a cell, whose disruption due to mitochondrial pore opening can cause cell death, leading to necrosis and many other diseases. The peptidyl-prolyl cis–trans isomerase cyclophilin D (CypD) is a key player in the regulation of the mitochondrial pore. The activity of CypD can be modulated by the post-translational modification (PTM). However, the detailed mechanism of this functional modulation is not well understood. Here, we investigate the catalytic mechanism of unmodified and modified CypD by calculating the reaction free energy profiles and characterizing the function-related conformational dynamics using molecular dynamics simulations and associated analyses. Our results …
A Hybrid Artificial Intelligence Model For Detecting Keratoconus, Zaid Abdi Alkareem Alyasseri, Ali H. Al-Timemy, Ammar Kamal Abasi, Alexandru Lavric, Husam Jasim Mohammed, Hidenori Takahashi, Jose Arthur Milhomens Filho, Mauro Campos, Rossen M. Hazarbassanov, Siamak Yousefi
A Hybrid Artificial Intelligence Model For Detecting Keratoconus, Zaid Abdi Alkareem Alyasseri, Ali H. Al-Timemy, Ammar Kamal Abasi, Alexandru Lavric, Husam Jasim Mohammed, Hidenori Takahashi, Jose Arthur Milhomens Filho, Mauro Campos, Rossen M. Hazarbassanov, Siamak Yousefi
Machine Learning Faculty Publications
Machine learning models have recently provided great promise in diagnosis of several ophthalmic disorders, including keratoconus (KCN). Keratoconus, a noninflammatory ectatic corneal disorder characterized by progressive cornea thinning, is challenging to detect as signs may be subtle. Several machine learning models have been proposed to detect KCN, however most of the models are supervised and thus require large well-annotated data. This paper proposes a new unsupervised model to detect KCN, based on adapted flower pollination algorithm (FPA) and the k-means algorithm. We will evaluate the proposed models using corneal data collected from 5430 eyes at different stages of KCN severity …
Potential Benefits Of The Campus Outdoor Built Environment On Student Stress, Leading To Improved Retention, Kevin Dilliard
Potential Benefits Of The Campus Outdoor Built Environment On Student Stress, Leading To Improved Retention, Kevin Dilliard
Graduate Liberal Studies Theses and Dissertations
University landscape managers often ask themselves, are they making a difference? Since what they do is not a revenue-generating department, how can they validate their true worth beyond making the campus beautiful, which is excellent, but what added value do they bring? As is common practice, when economic times get tough, the landscape department budget is one of the first to be cut, but is that the wisest thing to do? This research was intended to explore the concept that the services landscape managers provide have a return on investment by providing an environment in which students can thrive and …
Regression Modeling Of Complex Survival Data Based On Pseudo-Observations, Rong Rong
Regression Modeling Of Complex Survival Data Based On Pseudo-Observations, Rong Rong
Statistical Science Theses and Dissertations
The restricted mean survival time (RMST) is a clinically meaningful summary measure in studies with survival outcomes. Statistical methods have been developed for regression analysis of RMST to investigate impacts of covariates on RMST, which is a useful alternative to the Cox regression analysis. However, existing methods for regression modeling of RMST are not applicable to left-truncated right-censored data that arise frequently in prevalent cohort studies, for which the sampling bias due to left truncation and informative censoring induced by the prevalent sampling scheme must be properly addressed. Meanwhile, statistical methods have been developed for regression modeling of the cumulative …