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Articles 121 - 150 of 7728
Full-Text Articles in Physical Sciences and Mathematics
Toxicity Profiling Of Engineered Nanomaterials Via Multivariate Dose Response Surface Modeling, Trina Patel, Donatello Telesca, Saji George, Andre Nel
Toxicity Profiling Of Engineered Nanomaterials Via Multivariate Dose Response Surface Modeling, Trina Patel, Donatello Telesca, Saji George, Andre Nel
COBRA Preprint Series
New generation in-vitro high throughput screening (HTS) assays for the assessment of engineered nanomaterials provide an opportunity to learn how these particles interact at the cellular level, particularly in relation to injury pathways. These types of assays are often characterized by small sample sizes, high measurement error and high dimensionality as multiple cytotoxicity outcomes are measured across an array of doses and durations of exposure. In this article we propose a probability model for toxicity profiling of engineered nanomaterials. A hierarchical framework is used to account for the multivariate nature of the data by modeling dependence between outcomes and thereby …
Elliptic Operators And Maximal Regularity On Periodic Little-Hölder Spaces, Jeremy Lecrone
Elliptic Operators And Maximal Regularity On Periodic Little-Hölder Spaces, Jeremy Lecrone
Department of Math & Statistics Faculty Publications
We consider one-dimensional inhomogeneous parabolic equations with higher-order elliptic differential operators subject to periodic boundary conditions. In our main result we show that the property of continuous maximal regularity is satisfied in the setting of periodic little-Hölder spaces, provided the coefficients of the differential operator satisfy minimal regularity assumptions.We address parameter-dependent elliptic equations, deriving invertibility and resolvent bounds which lead to results on generation of analytic semigroups. We also demonstrate that the techniques and results of the paper hold for elliptic differential operators with operator-valued coefficients, in the setting of vector-valued functions.
The Acs Survey Of Galactic Globular Clusters. Xi. The Three-Dimensional Orientation Of The Sagittarius Dwarf Spheroidal Galaxy And Its Globular Clusters, Michael H. H. Siegel, Steven R. Majewski, David R. Law, Ata Sarajedini, Aaron Dotter, A Marín-Franch, Brian Chaboyer
The Acs Survey Of Galactic Globular Clusters. Xi. The Three-Dimensional Orientation Of The Sagittarius Dwarf Spheroidal Galaxy And Its Globular Clusters, Michael H. H. Siegel, Steven R. Majewski, David R. Law, Ata Sarajedini, Aaron Dotter, A Marín-Franch, Brian Chaboyer
Dartmouth Scholarship
We use observations from the Hubble Space Telescope Advanced Camera for Surveys (HST/ACS) study of Galactic globular clusters to investigate the spatial distribution of the inner regions of the disrupting Sagittarius dwarf spheroidal galaxy (Sgr). We combine previously published analyses of four Sgr member clusters located near or in the Sgr core (M54, Arp 2, Terzan 7, and Terzan 8) with a new analysis of diffuse Sgr material identified in the background of five low-latitude Galactic bulge clusters (NGC 6624, 6637, 6652, 6681, and 6809) observed as part of the ACS survey. By comparing the bulge cluster color-magnitude …
An Updated Gps Velocity Field For Puerto Rico And The Virgin Islands: Constraints On Tectonic Setting And Internal-Deformation, Desmond Kelvin Ihemedu
An Updated Gps Velocity Field For Puerto Rico And The Virgin Islands: Constraints On Tectonic Setting And Internal-Deformation, Desmond Kelvin Ihemedu
Earth & Environmental Sciences Theses - Archive
Puerto Rico and the northern Virgin Islands define the eastern end of the Greater Antilles, while the Puerto Rico trench and the Muertos Trough define the northern and the southern limits of the North American - Caribbean plate boundary zone. Three microplates have been defined: (1) Gonave, to the west; (2) Hispaniola, at the center; and (3) Puerto Rico and the northern Virgin Islands (PRVI) at the eastern end. Global Positioning System (GPS) geodesy was previously conducted in this region from 1994 to 2003. It was concluded that the locus of the highest permissible on-surface deformation in Puerto Rico and …
Structures, Energetics And Vibrational Frequency Shifts Of Hydrated Pyrimidine, J. Coleman Howard, Nathan I. Hammer, Gregory S. Tschumper
Structures, Energetics And Vibrational Frequency Shifts Of Hydrated Pyrimidine, J. Coleman Howard, Nathan I. Hammer, Gregory S. Tschumper
Chemistry Faculty Research & Creative Works
More than 70 unique micro-hydrated structures of pyrimidine, ranging in size from 1 to 7 water molecules, have been characterized with the B3LYP density functional and the 6-311++G(2df,2pd) triple-ζ split-valence basis set. Explicitly correlated MP2-F12 single-point computations were performed on each structure with a correlation consistent triple-ζ basis set to estimate the relative and dissociation energies at the MP2 complete basis set (CBS) limit. Many of these new structures have significantly lower energies than those previously reported (by as much as 12.66 kcal mol-1). For clusters with 1 and 2 water molecules, the MP2-F12 relative and dissociation energies are virtually …
Affinity Chromatography In Environmental Analysis And Drug-Protein Interaction Studies, Efthimia Papastavros
Affinity Chromatography In Environmental Analysis And Drug-Protein Interaction Studies, Efthimia Papastavros
Department of Chemistry: Dissertations, Theses, and Student Research
This dissertation will examine the use of novel affinity sorbents to extract emerging contaminants from water. These contaminants include carbamazepine, an anti-epileptic drug which is resistant to natural degradation in the environmental and to drinking water treatment procedures. This drug has been found in fish, drinking water, estuarine and coastal waters, and river sediment and has been used as a general marker of contaminants in wastewater. Carbamazepine was one of the most commonly detected compounds in surface-water and groundwater samples in a recent reconnaissance study of untreated drinking water sources in the U.S. Besides using this drug as a representative …
A New Mass Spectrometer For Upper Atmospheric Measurements In The Auroral Region, Addison E. Everett, James S. Dyer, Mike Watson, Wayne Sanderson, Scott Schicker, Dalon Work, Christopher J. Mertens, Scott M. Bailey, Erik A. Syrstad
A New Mass Spectrometer For Upper Atmospheric Measurements In The Auroral Region, Addison E. Everett, James S. Dyer, Mike Watson, Wayne Sanderson, Scott Schicker, Dalon Work, Christopher J. Mertens, Scott M. Bailey, Erik A. Syrstad
Graduate Student Posters
We have previously presented a new rocket-borne time-of-flight mass spectrometer (TOF-MS) for measurements in the mesosphere / lower thermosphere (MLT). Traditionally, mass spectrometry in the MLT has been difficult, mainly due to the elevated ambient pressures of the MLT and high speeds of a sounding rocket flight, which affect the direct sampling of the ambient atmosphere and spatial resolution. The TOF-MS is a versatile, inherently adaptable, axial-sampling instrument, capable of operating in a traditional TOF mode or in a multiplexing Hadamard-transform mode where high spatial resolution is desired. To minimize bow shock effects at low altitudes (~70-110km), the ram surface …
The Role Of Attached And Free-Living Bacteria In Biodegradation In Karst Aquifers, Roger Painter, Tom Byl, Lonnie Sharpe, Ahmad Kheder, Justin Harris
The Role Of Attached And Free-Living Bacteria In Biodegradation In Karst Aquifers, Roger Painter, Tom Byl, Lonnie Sharpe, Ahmad Kheder, Justin Harris
Civil and Architectural Engineering Faculty Research
Natural attenuation of groundwater contamination occurs at some level for all aquifers impacted with organic contaminants. The issues regarding natural attenuation are whether it takes place at a sufficient rate to be protective of human health and the environment. Implementation of a Monitored Natural Attenuation (MNA) remedial alternative for groundwater requires parties responsible for the contamination to demonstrate to regulators and the public that MNA is protective at a given site. Analysis of MNA for remediation of karst aquifers is hampered by a lack of understanding of biodegradation in karst environments. The lack of studies examining biodegradation in karst aquifers …
Viscoelastic Transition And Yield Strain Of The Folded Protein, Yong Wang, Giovanni Zocchi
Viscoelastic Transition And Yield Strain Of The Folded Protein, Yong Wang, Giovanni Zocchi
Physics Faculty Publications and Presentations
For proteins, the mechanical properties of the folded state are directly related to function, which generally entails conformational motion. Through sub-Angstrom resolution measurements of the AC mechanical susceptibility of a globular protein we describe a new fundamental materials property of the folded state. For increasing amplitude of the forcing, there is a reversible transition from elastic to viscoelastic response. At fixed frequency, the amplitude of the deformation is piecewise linear in the force, with different slopes in the elastic and viscoelastic regimes. Effectively, the protein softens beyond a yield point defined by this transition. We propose that ligand induced conformational …
A Hierarchical Image Processing Approach For Diagnostic Analysis Of Microcirculation Videos, Nazanin Mirshahi
A Hierarchical Image Processing Approach For Diagnostic Analysis Of Microcirculation Videos, Nazanin Mirshahi
Theses and Dissertations
Knowledge of the microcirculatory system has added significant value to the analysis of tissue oxygenation and perfusion. While developments in videomicroscopy technology have enabled medical researchers and physicians to observe the microvascular system, the available software tools are limited in their capabilities to determine quantitative features of microcirculation, either automatically or accurately. In particular, microvessel density has been a critical diagnostic measure in evaluating disease progression and a prognostic indicator in various clinical conditions. As a result, automated analysis of the microcirculatory system can be substantially beneficial in various real-time and off-line therapeutic medical applications, such as optimization of resuscitation. …
Synthesis And Characterization Of Highly Porous Borazine-Linked Polymers Via Dehydrogenation/Dehydrocoupling Of Borane-Amine Adducts And Their Applications To Gas Storage, Karl Jackson
Theses and Dissertations
A new class of porous polymers has been designed and successfully synthesized by thermal dehydrogenation of several polytopic arylamine-borane adducts and has been designated Borazine-Linked Polymers (BLPs). The polymers reported are constructed of linear, triangular, and tetrahedral amine building units to form 2D and 3D frameworks. The boron sites of the pores are aligned with hydrogen atoms contrasted with the recently reported halogenated BLPs which consist of pore channels aligned with bromine or chlorine atoms. One of the reported BLPs, BLP-2(H), was proven to be crystalline by PXRD, matching the experimental pattern to theoretical patterns calculated from modeled structures. BLPs …
An Integrated Geophysical And Geologic Study Of The Paleogene-Age Volcanic Body And Possible Landslide Deposit On The South Slope Of The Traverse Mountains, Utah, John C. Hoopes
Theses and Dissertations
Development of homes, roads, and commercial buildings in northern Utah has grown significantly during the last several decades. Construction has expanded from the valley floor to higher elevations of benches, foothills, and other elevated regions of the Wasatch Mountain Front. Construction in the higher elevation areas are a concern due to potential for landslides, both new and reactivated. Landslides have been identified in this region and are dated as Pleistocene to historical in age. A possible landslide of about 0.5 km2 on the south slope of Traverse Mountain has been mapped by the Utah Geological Survey in 2005. Its surface …
Screening Designs That Minimize Model Dependence, Kenneth P. Fairchild
Screening Designs That Minimize Model Dependence, Kenneth P. Fairchild
Theses and Dissertations
When approaching a new research problem, we often use screening designs to determine which factors are worth exploring in more detail. Before exploring a problem, we don't know which factors are important. When examining a large number of factors, it is likely that only a handful are significant and that even fewer two-factor interactions will be significant. If there are important interactions, it is likely that they are connected with the handful of significant main effects. Since we don't know beforehand which factors are significant, we want to choose a design that gives us the highest probability a priori of …
The Fierce Green Fire: Vol. 2 Issue 13, Wofford College Environmental Studies Program
The Fierce Green Fire: Vol. 2 Issue 13, Wofford College Environmental Studies Program
The Fierce Green Fire
No abstract provided.
A High-Eccentricity Component In The Double-Planet System Around Hd 163607 And A Planet Around Hd 164509*, Matthew J. Giguere, Debra A. Fischer, Andrew W. Howard, John A. Johnson, Gregory W. Henry, Jason T. Wright, Geoffrey W. Marcy, Howard Isaacson, Fengji Hou, Julien Spronck
A High-Eccentricity Component In The Double-Planet System Around Hd 163607 And A Planet Around Hd 164509*, Matthew J. Giguere, Debra A. Fischer, Andrew W. Howard, John A. Johnson, Gregory W. Henry, Jason T. Wright, Geoffrey W. Marcy, Howard Isaacson, Fengji Hou, Julien Spronck
Information Systems and Engineering Management Research Publications
We report the detection of three new exoplanets from Keck Observatory. HD 163607 is a metal-rich G5IV star with two planets. The inner planet has an observed orbital period of 75.29 ± 0.02 days, a semi-amplitude of 51.1 ± 1.4 m s−1, an eccentricity of 0.73 ± 0.02, and a derived minimum mass of MPsin i = 0.77 ± 0.02 MJup. This is the largest eccentricity of any known planet in a multi-planet system. The argument of periastron passage is 78.7 ± 2fdg0; consequently, the planet's closest approach to its parent star is very near the line of sight, leading …
Quantification Of Glacier Melt Volume In The Indus River Watershed, Maria Nicole Asay
Quantification Of Glacier Melt Volume In The Indus River Watershed, Maria Nicole Asay
Theses and Dissertations
Quantifying the contribution of glaciers to water resources is particularly important in locations where glaciers may provide a large percentage of total river discharge. In some remote locations, direct field measurements of melt rates are difficult to acquire, so alternate approaches are needed. Positive degree-day modeling (PDD) of glacier melt is a valuable tool to making first order approximations of the volume of melt coming from glaciers. In this study, a PDD-melt model is applied to glaciers in the Indus River watershed located in Afghanistan, China, India, and Pakistan. Here, millions of people rely on the water from the Indus …
Quality Selection For Dynamic Adaptive Streaming Over Http With Scalable Video Coding, Travis L. Andelin
Quality Selection For Dynamic Adaptive Streaming Over Http With Scalable Video Coding, Travis L. Andelin
Theses and Dissertations
Video streaming on the Internet is increasingly using Dynamic Adaptive Streaming over HTTP (DASH), in which the video is converted into various quality levels and divided into two-second segments. A client can then adjust its video quality over time by choosing to download the appropriate quality level for a given segment using standard HTTP. Scalable Video Coding (SVC) is a promising enhancement to the DASH protocol. With SVC, segments are divided into subset bitstream blocks. At playback, blocks received for a given segment are combined to additively increase the current quality. Unlike traditional DASH, which downloads segments serially, this encoding …
2011 Fall Engr333 Student Seminar Presentation, 2011 Fall Engr333
2011 Fall Engr333 Student Seminar Presentation, 2011 Fall Engr333
ENGR 333
File for student presentation, given by students in the Fall 2010 class of ENGR333.
Flexible Multitouch Electroluminescent Display, Michael E. Miller, John W. Harmer
Flexible Multitouch Electroluminescent Display, Michael E. Miller, John W. Harmer
AFIT Patents
A display device including a touch sensitive EL display having a flexible substrate; one or more power busses and one or more EL elements disposed over the flexible substrate; and a plurality of distributed chiplets arranged so that at least two chiplets are associated with each of a plurality of touch sensitive areas on the EL display and for sensing stress or strain associated with bending of the flexible substrate or the chiplet substrate to provide respective displacement signals corresponding to the touch sensitive areas; each chiplet connected to one or more of the power busses and one or more …
Do You Believe The Climate Is Changing? Answers From New Survey Research, Lawrence C. Hamilton
Do You Believe The Climate Is Changing? Answers From New Survey Research, Lawrence C. Hamilton
Carsey Publications
This brief explores how political views influence Americans’ understanding and perception of science. The research is based on a national version of the Community and Environment in Rural America survey called NCERA, and on New Hampshire’s statewide Granite State Poll. Author Lawrence Hamilton reports that most people on both surveys feel that they understand either a great deal or a moderate amount about global warming or climate change. However, deep partisan divisions affect both personal beliefs about climate change and perceptions of agreement among scientists. Democrats are much more likely to state they believe that climate change is happening, caused …
Partial Connectivity In Wireless Sensor Networks, Robert Andre Murphy
Partial Connectivity In Wireless Sensor Networks, Robert Andre Murphy
Dissertations
Given a bounded region of the 2-dimensional plane, a discrete set of nodes is distributed throughout according to a Poisson point process. Given some fixed, finite, real number, two nodes are said to connect and form an edge if their mutual distance is less than this number. Let G be the graph of all such edges over the set of generated nodes and let C be any set of mutually connected nodes. It is shown that there is a critical mutual distance such that at least half of all generated nodes are mutually connected to form a connected cluster. Now, …
Remote Analysis Of Grain Size Characteristic In Submarine Pyroclastic Deposits From Kolumbo Volcano, Greece, Clara Smart, D. P. Whitesell, Christopher N. Roman, Steven Carey
Remote Analysis Of Grain Size Characteristic In Submarine Pyroclastic Deposits From Kolumbo Volcano, Greece, Clara Smart, D. P. Whitesell, Christopher N. Roman, Steven Carey
Graduate School of Oceanography Faculty Publications
Grain size characteristics of pyroclastic deposits provide valuable information about source eruption energetics and depositional processes. Maximum size and sorting are often used to discriminate between fallout and sediment gravity flow processes during explosive eruptions. In the submarine environment the collection of such data in thick pyroclastic sequences is extremely challenging and potentially time consuming. A method has been developed to extract grain size information from stereo images collected by a remotely operated vehicle (ROV). In the summer of 2010 the ROV Hercules collected a suite of stereo images from a thick pumice sequence in the caldera walls of Kolumbo …
Analyzing Ecohydrology Of Subirrigated Meadow, Dry Valley And Upland Dune Ecosystems Using Remote Sensing And In-Situ Estimations In The Semiarid Sand Hills Region Of Nebraska, Usa, Nathan C. Healey
School of Natural Resources: Dissertations, Theses, and Student Research
Nebraska’s dependence upon the High Plains (Ogallala) Aquifer for agricultural production is vital to the state’s economy, ecology and hydrology. The Sand Hills region (58,000 km2) of Nebraska is a unique system of lakes, (~5%) wetlands, (~10%) subirrigated meadows, (~20%) dry valleys and (~65%) upland sand dune ecosystems. Understanding how each of these land cover types reacts to climate conditions of different water limitations is vital to regional water resource management. This research explores the ecohydrological behavior of different land cover types at the Gudmundsen Sand Hills Research Laboratory (GSRL) near Whitman, Nebraska in the heart of the …
Nanozeolites Doped Photopolymer Layers With Reduced Shrinkage, Mohesh Moothanchery, Izabela Naydenova, Svetlana Mintova, Vincent Toal
Nanozeolites Doped Photopolymer Layers With Reduced Shrinkage, Mohesh Moothanchery, Izabela Naydenova, Svetlana Mintova, Vincent Toal
Articles
An acrylamide based photopolymer doped with pure silica MFI-type zeolite (silicalite-1) nanoparticles has been characterized for holographic recording purposes. The concentrations of the silicalite-1 nanoparticles in the photopolymer layers were 1, 2.5, 5 and 7.5 wt.%. The inclusion of silicalite-1 nanoparticle in the photopolymer has resulted in an increase of the diffraction efficiency by up to 40%, and decrease of the shrinkage from 1.32% to 0.57%. The best results were obtained in layers doped with 5 wt.% silicalite-1 nanoparticles.
Dynamic Appointment Scheduling In Healthcare, Mckay N. Heasley
Dynamic Appointment Scheduling In Healthcare, Mckay N. Heasley
Theses and Dissertations
In recent years, healthcare management has become fertile ground for the scheduling theory community. In addition to an extensive academic literature on this subject, there has also been a proliferation of healthcare scheduling software companies in the marketplace. Typical scheduling systems use rule-based analytics that give schedulers advisory information from programmable heuristics such as the Bailey-Welch rule cite{B,BW}, which recommends overbooking early in the day to fill-in potential no-shows later on. We propose a dynamic programming problem formulation to the scheduling problem that maximizes revenue. We formulate the problem and discuss the effectiveness of 3 different algorithms that solve the …
Detection Of Diffuse Sea Floor Venting Using Structured Light Imaging, Gabrielle Inglis, Clara Smart, Christopher Roman, Steven Carey
Detection Of Diffuse Sea Floor Venting Using Structured Light Imaging, Gabrielle Inglis, Clara Smart, Christopher Roman, Steven Carey
Graduate School of Oceanography Faculty Publications
Efficiently identifying and localizing diffuse sea floor venting at hydrothermal and cold seep sites is often difficult. Actively venting fluids are usually identified by a temperature induced optical shimmering seen during direct visual inspections or in video data collected by vehicles working close to the sea floor. Relying on such direct methods complicates establishing spatial relations between areas within a survey covering a broad area. Our recent work with a structured light laser system has shown that venting can also be detected in the image data in an automated fashion. A structured light laser system consists of a camera and …
Acrb Trimer Stability And Efflux Activity, Insight From Mutagenesis Studies, Linliang Yu, Wei Lu, Yinan Wei
Acrb Trimer Stability And Efflux Activity, Insight From Mutagenesis Studies, Linliang Yu, Wei Lu, Yinan Wei
Chemistry Faculty Publications
The multidrug transporter AcrB in Escherichia coli exists and functions as a homo-trimer. The assembly process of obligate membrane protein oligomers, including AcrB, remains poorly understood. In a previous study, we have shown that individual AcrB subunit is capable of folding independently, suggesting that trimerization of AcrB follows a three-stage pathway in which monomers first fold, and then assemble. Here we destabilized the AcrB trimer through mutating a single Pro (P223) in the protruding loop of AcrB, which drastically reduced the protein activity. We replaced P223 separately with five residues, including Ala, Val, Tyr, Asn, and Gly, and found that …
The Laboca Survey Of The Extended Chandra Deep Field-South: Clustering Of Submillimetre Galaxies, Ryan C. Hickox, J. L. Wardlow, Ian Smail, A. D. Myers
The Laboca Survey Of The Extended Chandra Deep Field-South: Clustering Of Submillimetre Galaxies, Ryan C. Hickox, J. L. Wardlow, Ian Smail, A. D. Myers
Dartmouth Scholarship
We present a measurement of the spatial clustering of submillimetre galaxies (SMGs) at z = 1–3. Using data from the 870 μm LABOCA submillimetre survey of the Extended Chandra Deep Field South, we employ a novel technique to measure the cross-correlation between SMGs and galaxies, accounting for the full probability distributions for photometric redshifts of the galaxies. From the observed projected two-point cross-correlation function we derive the linear bias and characteristic dark matter halo masses for the SMGs. We detect clustering in the cross-correlation between SMGs and galaxies at the > 4σ level. Accounting for the clustering of galaxies from their …
User Choice Between Traditional And Computerized Methods: An Activity Perspective, Jun Sun
User Choice Between Traditional And Computerized Methods: An Activity Perspective, Jun Sun
Information Systems Faculty Publications
Numerous computerized methods emerge to replace traditional methods in people’s personal, work and social lives, but many are hesitant to make the transition. This study examines the factors that influence human choice between different methods. According to Activity Theory, traditional and computerized methods are both tools that a person uses for a certain task. The situated experiences with various methods shape people’s attitude toward using them later in terms of tool readiness. The understanding leads to hypothesized relationships between user-, method- and task-specific factors and the dependent variable. The results from an empirical study support that method experiences have strong …
A Search For The Transit Of Hd 168443b: Improved Orbital Parameters And Photometry, Genady Pilyavsky, Suvrath Mahadevan, Stephen R. Kane, Andrew W. Howard, David R. Ciardi, Chris De Pree, Diana Dragomir, Debra A. Fischer, Gregory W. Henry, Eric L. N. Jensen, Gregory Laughlin
A Search For The Transit Of Hd 168443b: Improved Orbital Parameters And Photometry, Genady Pilyavsky, Suvrath Mahadevan, Stephen R. Kane, Andrew W. Howard, David R. Ciardi, Chris De Pree, Diana Dragomir, Debra A. Fischer, Gregory W. Henry, Eric L. N. Jensen, Gregory Laughlin
Information Systems and Engineering Management Research Publications
The discovery of transiting planets around bright stars holds the potential to greatly enhance our understanding of planetary atmospheres. In this work we present the search for transits of HD 168443b, a massive planet orbiting the bright star HD 168443 (V = 6.92) with a period of 58.11 days. The high eccentricity of the planetary orbit (e = 0.53) significantly enhances the a priori transit probability beyond that expected for a circular orbit, making HD 168443 a candidate for our ongoing Transit Ephemeris Refinement and Monitoring Survey. Using additional radial velocities from Keck High Resolution Echelle Spectrometer, we refined the …