Physical Sciences and Mathematics Commons^™

A Bayesian Mixture Model Relating Dose To Critical Organs And Functional Complication In 3d Conformal Radiation Therapy, Tim Johnson, Jeremy Taylor, Randall K. Ten Haken, Avraham Eisbruch

The University of Michigan Department of Biostatistics Working Paper Series

A goal of radiation therapy is to deliver maximum dose to the target tumor while minimizing complications due to irradiation of critical organs. Technological advances in 3D conformal radiation therapy has allowed great strides in realizing this goal, however complications may still arise. Critical organs may be adjacent to tumors or in the path of the radiation beam. Several mathematical models have been proposed that describe a relationship between dose and observed functional complication, however only a few published studies have successfully fit these models to data using modern statistical methods which make efficient use of the data. One complication …

Absorption, Distribution, And Excretion Of [14C]-3-Chloro-4 Methylaniline Hydrochloride In Two Species Of Birds Following A Single Oral Dose, David A. Goldade, John D. Tessari, John J. Johnston

United States Department of Agriculture Wildlife Services: Staff Publications

Ring-labeled [¹⁴C]-3-chloro-4-methylaniline hydrochloride (250 μg per bird) was delivered to 21 red-winged blackbirds (Agelaius phoeniceus) and 21 dark-eyed juncos (Junco hyemalis) via oral gavage, and the distribution and excretion of radioactivity were determined at 15 and 30 min and 1, 4, 8, 12, and 24 h (n = 3 per time point). Direct measurement of radioactivity as well as measurement following combustion was accomplished using a liquid scintillation counter. Elimination from most tissues followed a two-compartment model, with very rapid elimination occurring between time 0 and 4 h and a much slower elimination …

Automating The Extraction Of Domain-Specific Information From The Web-A Case Study For The Genealogical Domain, Troy L. Walker

Theses and Dissertations

Current ways of finding genealogical information within the millions of pages on the Web are inadequate. In an effort to help genealogical researchers find desired information more quickly, we have developed GeneTIQS, a Genealogy Target-based Information Query System. GeneTIQS builds on ontology-based methods of data extraction to allow database-style queries on the Web. This thesis makes two main contributions to GeneTIQS. (1) It builds a framework to do generic ontology-based data extraction. (2) It develops a hybrid record separator based on Vector Space Modeling that uses both formatting clues and data clues to split pages into component records. The record …

Measurements Of Transverse Energy Distributions In Au+Au Collisions At √SNn=200 Gev, Star Collaboration, T.D. Gutierrez

Physics

Transverse energy (E_T) distributions have been measured for Au+Au collisions at √s_NN=200GeV by the STAR Collaboration at RHIC. E_T is constructed from its hadronic and electromagnetic components, which have been measured separately. E_T production for the most central collisions is well described by several theoretical models whose common feature is large energy density achieved early in the fireball evolution. The magnitude and centrality dependence of E_T per charged particle agrees well with measurements at lower collision energy, indicating that the growth in E_T for larger collision energy results from the growth in …

Target-Dominant Chinese-English Machine Translation, Dan Su

Theses and Dissertations

Information exchange is increasing rapidly with the advent of globalization. As the language spoken by the most people in today's world, Chinese will play an important role in information exchange in the future. Therefore, we need an efficient and practical means to access the increasingly large volume of Chinese data. This thesis describes a target-dominant Chinese-English machine translation system, which can translate a given Chinese news sentence into English. We conjecture that we can improve the state of the art of MT using a TDMT approach. This system has participated in the NIST (National Institute of Standards and Technology) 2004 …

Simulation Of Ultrashort Electron Pulse Generation From Optical Injection Into Wake-Field Plasma Waves, D.S. Dodd, J.K. Kim, Donald P. Umstadter

Donald Umstadter Publications

A laser-plasma-based source of relativistic electrons is described in detail, and analyzed in two dimensions using theoretical and numeric techniques. Two laser beams are focused in a plasma, one exciting a wake-field electron plasma wave while another locally alters some electron trajectories in such a way that they can be trapped and accelerated by the wave. Previous analyses dealt only with one-dimensional models. In this paper two-dimensional particle-in-cell simulations and analysis of single particle trajectories show that the radial wake field plays an important role. The simulation results are interpreted to evaluate the accelerated electron beam's properties and compared with …

Local Optical Properties, Electron Densities, And London Dispersion Energies Of Atomically Structured Grain Boundaries, Roger H. French

Faculty Scholarship

Quantitative analysis of spatially resolved valence electron energy-loss spectra shows strong physical property contrasts for Σ5 and near Σ13 grain boundaries in Fe-doped SrTiO3, resulting in London dispersion interaction energies of 14 to 50mJ/m2 between the adjacent grains. The determination of local physical properties of grain boundary cores and the appreciable contribution of long-range London dispersion to interface energies provides new information on formation and control of interfaces in materials.

Electrical Properties And Raman Scattering Study Of Single Crystal Cs2nb4o11, Jianjun Liu, E. P. Kharitonova, Chun-Gang Duan, Wai-Ning Mei, Robert W. Smith, John R. Hardy

Chemistry Faculty Publications

We studied temperature dependence of complex capacitance, impedance, and polarized Raman spectra of single crystal Cs2Nb4O11. First, we observed a sharp-shaped peak at 165 ^oC in the complex capacitance, then found drastic changes in the Raman spectra in the same temperature range. Utilizing the pseudosymmetry search of structure space group, we attributed the observed anomalies to a structural change from the room temperature orthorhombic Pnn2 to another or- thorhombic Imm2. We also measured room temperature polarized Raman spectra in different symmetries of normal vibrations and assigned high wavenumber Raman bands to the internal vibrations of NbO6 octahedra and NbO4 …

The Structures Of C-C4F8 And C-C4F8¯ And The Adiabatic Electron Affinity Of C-C4F8, Gordon A. Gallup

Gordon Gallup Publications

Calculations at the 6311G(dps) level have been used to elucidate the structures of octafluorocyclobutane c-C₄F₈ and its negative ion c-C₄F₈^¯. With no empirical adjustments, we obtain 0.640 eV for the adiabatic electron affi nity of c-C₄F₈. This may be compared with an experimental value of 0.63 ± 0.05 eV from the FALP method. c-C₄F₈ has unusual features in that there is an increase in symmetry, D_2d to D_4h, in going from the neutral molecule to the negative ion, and …

Characterizing The Regulatory Environment Affecting The Forest Products Industry In California, Richard Thompson, Christopher Dicus

Natural Resources Management and Environmental Sciences

No abstract provided.

Mechanism And Control Of High-Intensity-Laser-Driven Proton Acceleration, T. Lin, K. Flippo, M. Rever, Anatoly Maksimchuk, Donald P. Umstadter

Donald Umstadter Publications

We discuss the optimization and control of laser-driven proton beams. Specifically, we report on the dependence of high-intensity laser accelerated proton beams on the material properties of various thin-film targets. Evidence of star-like filaments and beam hollowing (predicted from the electrothermal instability theory) is observed on Radiochromic Film (RCF) and CR-39 nuclear track detectors. The proton beam spatial profile is found to depend on initial target conductivity and target thickness. For resistive target materials, these structured profiles are explained by the inhibition of current, due to the lack of a return current. The conductors, however, can support large propagating currents …

Nonlinear Parallel And Perpendicular Diffusion Of Charged Cosmic Rays In Weak Turbulence, Andreas Schalchi, John William Bieber, William H. Matthaeus, Gang Qin

Aerospace, Physics, and Space Science Faculty Publications

The problem of particle transport perpendicular to a magnetic background field is well known in cosmic-ray astrophysics. Whereas it is widely accepted that quasi-linear theory (QLT) of particle transport does not provide the correct results for perpendicular diffusion, it was assumed for a long time that QLT is the correct theory for parallel diffusion. In the current paper we demonstrate that QLT is in general also incorrect for parallel particle transport if we consider composite turbulence geometry. Motivated through the recent success of the so-called nonlinear guiding center theory of perpendicular diffusion, we present a new theory for parallel and …

The Nuclear Reddening Curve For Active Galactic Nuclei And The Shape Of The Infrared To X-Ray Spectral Energy Distribution, C. Martin Gaskell, René W. Goosmann, Robert R. J. Antonucci, David H. Whysong

Department of Physics and Astronomy: Faculty Publications

We present extinction curves derived from the broad emission lines and continua of samples of 72 radio-loud and 1018 radio-quiet active galactic nuclei (AGNs). The curves are significantly flatter in the UV than curves for the local interstellar medium. The reddening curves for the radio-quiet Large Bright Quasar Survey quasars are slightly steeper than those of the radio-loud quasars in the UV, probably because of additional reddening by dust farther out in the host galaxies of the former. The UV extinction curves for the radio-loud AGNs are very flat. This is explicable with slight modifications to standard Mathis-Rumpl-Nordsieck dust models: …

Calcium Responses Of Chicken Trigeminal Ganglion Neurons To Methyl Anthranilate And Capsaicin, Michael L. Kirifides, Michael P. Kurnellas, Larry Clark, Bruce P. Bryant

United States Department of Agriculture Wildlife Services: Staff Publications

Using digital fluorescence imaging, we determined the effects of methyl anthranilate (MA), an avian irritant, and capsaicin (CAP), a mammalian irritant, on intracellular calcium ([Ca2+]i) in chicken trigeminal neurons. Concentration–response functions indicated that the threshold for inducing increases in [Ca2+]i was higher for CAP (30·mmol·l–1) than for MA (10·mmol·l–1). The maximum magnitudes of [Ca2+]i in response to MA and CAP were compared after normalization to 40·mmol·l–1 KCl. At equal concentrations (300·mmol·l–1), trigeminal neurons responded with a greater change in [Ca2+]i to MA (78% of KCl) than to CAP (43% of KCl). Furthermore, at 300·mmol·l–1, 48% of neurons responded to MA …

Bicistronic And Fused Monocistronic Transcripts Are Derived From Adjacent Loci In The Arabidopsis Genome, Jyothi Thimmapuram, Hui Duan, Lei Liu, Mary A. Schuler

Cyber Center Publications

Comparisons of full-length cDNAs and genomic DNAs available for Arabidopsis thaliana described here indicate that some adjacent loci are transcribed into extremely long RNAs spanning two annotated genes. Once expressed, some of these transcripts are post-transcriptionally spliced within their coding and intergenic sequences to generate bicistronic transcripts containing two complete open reading frames. Others are spliced to generate monocistronic transcripts coding for fusion proteins with sequences derived from both loci. RT-PCR of several P450 transcripts in this collection indicates that these extended transcripts exist side by side with shorter monocistronic transcripts derived from the individual loci in each pair. The …

Tandem Intramolecular Nicholas And Pauson-Khand Reactions For The Synthesis Of Tricyclic Oxygen-Containing Heterocycles, Miriam M. Quintal, Kristina D. Closser, Kevin M. Shea

Chemistry: Faculty Publications

Simple acyclic enynes can be easily converted into tricyclic ethers upon treatment with Co2(CO)8followed by Nicholas and Pauson−Khand reactions. Tricyclic [5,8,5]- and [5,7,5]-systems can be prepared in high overall yields in only seven synthetic steps.

Bell’S Inequalities For Particles Of Arbitrary Spin In Fixed Analyzers, Ronen Mukamel, John C. Howell

Mathematics, Physics, and Computer Science Faculty Articles and Research

We propose a new set of observables for experiments on entangled particles of arbitrarily large spin that produce significant Clauser-Horne-Shimony-Holt inequality violations for fixed analyzer settings over a wider range of spins than was previously possible. These observables are better suited for experiments where analyzer orientations must be chosen before the spin of the entangled particles is known, such as experiments using polarization entangled downconverted photons.

Combination Of Cdf And D0 Results On The W Boson Mass And Width, Darin Acosta, Kenneth A. Bloom, Collider Detector At Fermilab Collaboration

Kenneth Bloom Publications

The results based on 1992–95 data (Run 1) from the CDF and D0 experiments on the measurements of the W boson mass and width are presented, along with the combined results. We report a Tevatron collider average M_W =80.456±0.059 GeV. We also report the Tevatron collider average of the directly measured W boson width Γ_W=2.115±0.105 GeV. We describe a new joint analysis of the direct W mass and width measurements. Assuming the validity of the standard model, we combine the directly measured W boson width with the width extracted from the ratio of W and Z boson …

Fueling Loading And Potential Fire Behavior After Selective Harvest In Coast Redwood Stands, Christopher Dicus

Natural Resources Management and Environmental Sciences

No abstract provided.

Choice Of Monitoring Mechanism For Optimal Nonparametric Functional Estimation For Binary Data, Nicholas P. Jewell, Mark J. Van Der Laan, Stephen Shiboski

U.C. Berkeley Division of Biostatistics Working Paper Series

Optimal designs of dose levels in order to estimate parameters from a model for binary response data have a long and rich history. These designs are based on parametric models. Here we consider fully nonparametric models with interest focused on estimation of smooth functionals using plug-in estimators based on the nonparametric maximum likelihood estimator. An important application of the results is the derivation of the optimal choice of the monitoring time distribution function for current status observation of a survival distribution. The optimal choice depends in a simple way on the dose response function and the form of the functional. …

Red Rock Desert Learning Center Core Group Meeting: November 16, 2004, Red Rock Desert Learning Center

Reports (RRLC)

1. Introductions (5 min.)
2. Approval of Minutes from October 19 Meeting (5 minutes)
3. Presentation of Biology Curriculum Strands – Paul Buck (15 min.)
4. Discussion of Possible Advisory Board Structures – Michael Reiland (15 min.)
5. Update from Line and Space Architects – Les Wallach/Henry Tom (20 min.)
6. Discussion of Student Risk Analysis/Liability Issues (15 min.)
7. Standing Reports (10 minutes)
   A. UNLV/CESU Update – Nancy Flagg
   B. BLM Update – Michael Reiland
8. Committee Reports (5 min.)
   A. Building Committee – Angie Lara
9. Open Discussion / New Business (5 min.)
   A. January Meeting – Tuesday, January 18, 10:30 a.m., UNLV Paradise
   Campus
   B. Core …

Perceptual Evaluation Of Point-Based Object Representation, Paul Schwarz

Computer Science Honors Theses

Researchers have proposed several methods of representing three-dimensional objects in computer memory along with different methods of displaying these objects on two-dimensional computer displays. Using a polygon-based representation that linearly interpolates between a set of sample points is by far the most popular way of representing objects today, mostly because of its ability to display an object on a computer screen at a fast and consistent rate. However, as graphics hardware increases in speed, polygon-based models prove to be increasingly inefficient. Point-based representations have been proposed that consist of densely sampling some surface and using solely the samples to portray …

Does The Halting Necessary For Hardware Trace Collection Inordinately Perturb The Results?, Myles G. Watson

Theses and Dissertations

Processor address traces are invaluable for characterizing workloads and testing proposed memory hierarchies. Long traces are needed to exercise modern cache designs and produce meaningful results, but are difficult to collect with hardware monitors because microprocessors access memory too frequently for disks or other large storage to keep up. The small, fast buffers of the monitors fill quickly; in order to obtain long contiguous traces, the processor must be stopped while the buffer is emptied. This halting may perturb the traces collected, but this cannot be measured directly, since long uninterrupted traces cannot be collected. We make the case that …

Real-Time Image Enhancement Using Texture Synthesis, Matthew J. Sorensen

Theses and Dissertations

This thesis presents an approach to real-time image enhancement using texture synthesis. Traditional image enhancement techniques are typically time consuming, lack realistic detail, or do not scale well for large magnification factors.

Real-time Enhancement using Texture Synthesis (RETS) combines interpolation, classification, and patch-based texture synthesis to enhance low-resolution imagery, particularly aerial imagery. RETS uses as input a low-resolution source image and several high-resolution sample textures. The output of RETS is a high-resolution image with the structure of the source image, but with detail consistent with the high-resolution sample textures. We show that RETS can enhance large amounts of imagery in …

Additive-Assisted Cerium-Based Electrolytic Coating Process For Corrosion Protection Of Aluminum Alloys, James O. Stoffer, Thomas J. O'Keefe, Eric L. Morris, Scott Hayes, Paul Yu, Alex Williams, Xuan Lin

Chemistry Faculty Research & Creative Works

The corrosion resistance of an aluminum or aluminum alloy component is enhanced by immersing an aluminum alloy to act as a cathode and an oxygen-evolving anode in an electrolyte comprising water, cerium ions, and an additive selected from among animal gelatin, derivatives of animal gelatin, and amino acids, then passing an electrical current through the electrolyte to deposit a cerium-based coating onto the aluminum-based component.

Synthesizing Realistic Spine Motion Using Traditional Rig Controllers, Jabbar Raisani

Computer Science Honors Theses

This thesis presents a specific method for simulating realistic spine motion through the use of traditional rig control objects. The spine's motion and flexibility is based on a curve as opposed to the more traditional three bone spine. This allows for a more fluid animation more closely resembling that of a spinal column. However, this setup keeps the traditional three control rig setup in order to mimic the control system of a traditional three bone spine. Currently, three bone systems are well understood by animators and the motion is easy to control. The problem with this setup is that although …

1-Hyperbolic Projection For User Interfaces, Alexander Kolliopoulos

Computer Science Honors Theses

The problem of dealing with representations of information that does not fit conveniently within allotted screen space is pervasive in graphical interfaces. While there are techniques for dealing with this problem in various ways, some properties of such existing techniques are not satisfying. For example, global structure of information may be lost in favor of local focus, or information may not be mapped into a rectangular area. The 1-hyperbolic interface is proposed to deal with some of these deficiencies, and the mathematics involved in display and interaction are derived. The calculations necessary for this interface are easy to implement, and …

On Marginalized Multilevel Models And Their Computation, Michael E. Griswold, Scott L. Zeger

Johns Hopkins University, Dept. of Biostatistics Working Papers

Clustered data analysis is characterized by the need to describe both systematic variation in a mean model and cluster-dependent random variation in an association model. Marginalized multilevel models embrace the robustness and interpretations of a marginal mean model, while retaining the likelihood inference capabilities and flexible dependence structures of a conditional association model. Although there has been increasing recognition of the attractiveness of marginalized multilevel models, there has been a gap in their practical application arising from a lack of readily available estimation procedures. We extend the marginalized multilevel model to allow for nonlinear functions in both the mean and …

Substructure Dependence Of Jet Cross Sections At Hera And Determination Of ΑS, S. Chekanov, M. Derrick, J. H. Loizides, S. Magill, S. Miglioranzi, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, N. Pavel, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, A. Montanari, R. Nania, F. Palmonari, A. Pesci, L. Rinaldi

Faculty Publications

No abstract provided.

Azaadamantane Benzamide 5-Ht4 Agonists: Gastrointestinal Prokinetic Sc-54750, Daniel Becker, Daniel L. Flynn, Robert L. Shone, Gary Gullikson

Chemistry: Faculty Publications and Other Works

Azaadamantanone 1 was converted to a series of aminoazaadamantane benzamides 9a–d, which were profiled for serotonin receptor activity. Aminomethylazaadamantane SC-54750 is a potent 5-HT4 agonist and 5-HT3 antagonist with in vivo efficacy in gastroparesis models and also inhibits cisplatin-induced emesis.