Physical Sciences and Mathematics Commons^™

Exploratory Data-Driven Models For Water Quality: A Case Study For Tampa Bay Water, Sandra Sekyere

USF Tampa Graduate Theses and Dissertations

Water, a crucial resource for sustaining life, covers approximately 70% of the earth's surface. Nonetheless, the quality of water is deteriorating rapidly due to the rapid growth of urban areas and industries, which is a worrying trend causing harm to human health and the ecosystem. Water quality forecasting has a key role in water resources management by enabling effective pollution control, ecosystem monitoring, and decision-making.

Previously, traditional statistical models were used to forecast water quality, but they were unable to examine the non-linear relationships between water quality parameters, and they assumed that all datasets were distributed normally. This study uses …

Ultracold Neutral Plasma Evolution In An External Magnetic Field, Chanhyun Pak

Theses and Dissertations

We study the expansion velocity and ion temperature evolution of ultracold neutral plasmas (UNPs) of calcium atoms under the influence of a uniform magnetic field that ranges up to 200 G. In the experiments, we use a magneto-optical trap (MOT) to capture the neutral atoms and laser-induced fluorescence (LIF) to take images of the plasma. We vary the magnetic field strengths and the initial electron temperatures and observe the plasma evolution in time. We compare the ion temperature evolution to the theory introduced in the paper by Pohl et. al. [Phys. Rev. A 70, 033416 (2004)]. The evolution of the …

Acoustic Directivity: Advances In Acoustic Center Localization, Measurement Optimization, Directional Modeling, And Sound Power Spectral Estimation, Samuel David Bellows

Theses and Dissertations

Sound radiation from an acoustic source typically exhibits directional behavior, as is the case for the human voice, musical instruments, and loudspeakers, to name just a few. The necessity of directional data for many applications, such as sound source modeling, microphone placement, room acoustical design, and auralization, motivates directivity measurements. However, these measurements require careful understanding and implementation to produce the most meaningful results. Accordingly, this dissertation addresses several topics relevant to directivity theory, measurement, processing, and application. It first expands and amends previously published concepts of an acoustic source center and demonstrates the close relationship between the center and …

Investigating The Activity Of Alternative Warheads For Targeted Covalent Inhibition Of The Inhibitor Vertebrate Lysozyme Protein From Pseudomonas Aeruginosa, Katie Hambrick

Master of Science in Chemical Sciences Theses

Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative bacterium that causes blood and lung infections in hospital environments due to its ability to survive on improperly sterilized medical equipment. P. aeruginosa has developed several multi-drug resistance mechanisms that make it very difficult to treat with current antibiotics.¹ This presents the need for a new class of antibiotics that cannot be overcome by P. aeruginosa’s mechanisms of resistance.

The primary goal of this project was to develop a small library of inhibitors that could later be incorporated into lead compounds for novel antibiotic drug discovery. One of P. …

Deep Learning Enhancement And Privacy-Preserving Deep Learning: A Data-Centric Approach, Hung S. Nguyen

USF Tampa Graduate Theses and Dissertations

Deep Learning and its applications have become attractive to a lot of research recentlybecause of its capability to capture important information from large amounts of data. While most of the work focuses on finding the best model parameters, improving machine learning performance from data perspective still needs more attention. In this work, we propose techniques to enhance the robustness of deep learning classification by tackling data issue. Specifically, our data processing proposals aim to alleviate the impacts of class-imbalanced data and non- IID data in deep learning classification and federated learning scenarios. In addition, data pre-processing strategies such that dimensionality …

Applications In Opioid Analysis With Faims Through Control Of Vapor Phase Solvent Modifiers, Nathan Grimes

USF Tampa Graduate Theses and Dissertations

Field Asymmetric Ion Mobility Spectrometry (FAIMS), often coupled with mass spectrometry (MS), offers rapid analytical ion filtration, useful in reducing matrix interference and differentiating isomeric compounds. This study focuses on augmenting FAIMS-MS analyses through the incorporation of gas phase solvents, or "modifiers," inducing dynamic microsolvation, a particularly potent method of analysis enhancement.

Initially, the research utilized a bubbler-based system, incorporating a humidity sensor, improving modifier concentration control when using water. Our application in opioid detection and differentiation revealed considerable advancements. Notably, an increased peak capacity in an opioid mixture and successful separation of the isobaric opioid pair, alfentanil and ortho-isopropyl …

Analysis Of Ostds Failure Potential Due To Sea-Level Rise And Other Inundation Factors: An Integrated Geo-Spatial Analysis, Alec Colarusso

USF Tampa Graduate Theses and Dissertations

While many aspects of climate change are well-studied, the vulnerability of Onsite Sewage Treatment and Disposal Systems (OSTDS) to sea-level rise (SLR) has not been thoroughly examined despite the potentially significant environmental impacts, including nutrient and pathogen loading. Research gaps include the need to determine the suitability of models to predict groundwater inundation due to SLR and the consequent impact on OSTDS. As such, this study aims to compare Bathtub/hydrostatic and physics-based/MODFLOW/3D numerical modeling methods of simulating groundwater inundation from SLR to identify OSTDS vulnerability to failure due to a reduction in the height of the vadose zone (saturation or …

Synthesis, Characterization, And Separation Of Loaded Liposomes For Drug Delivery, Sandra Khalife

USF Tampa Graduate Theses and Dissertations

Liposomes are viable candidates for drug delivery vehicles due to their ability to protect loaded compounds, dampen side effects of drugs, and be delivered to target sites in the body. The amphipathic nature of these lipid vesicles makes them very customizable through careful selection of bilayer and aqueous core components as well as synthetic and downsizing methods. However, synthetic methods may result in unencapsulated compounds remaining present alongside loaded liposomes, which require removal before the liposome suspension can be used.

This work explores the use of model DOPC as well as DOPC and CHOL liposomes and the methods that were …

Environmental Chemical Analysis Method Optimization And Application To Northwest Cuban Marine Sediment, Thea R. Bartlett

USF Tampa Graduate Theses and Dissertations

A method for gas chromatography tandem mass spectrometry (GC-MS/MS) in selected reaction monitoring (SRM) mode has been optimized to quantify 250 compounds of a variety of compound classes such as polycyclic aromatic hydrocarbons (PAHs), oxidized PAHs, organochlorinated pesticides, polychlorinated biphenyls, biomarkers (hopanes, steranes, tri-aromatic steroids, and fecal sterols), aliphatic hydrocarbons, and plastic additives. This method was validated based on available QA/QC standards using several environmental samples, both sediment and biota, and standard reference materials. This contaminant-focused method can be used as a forensic geochemistry tool to evaluate oil contamination and other contaminant histories in future research studies. When applied to …

Stable Isotope Analysis Of Doryteuthis (Amerigo) Pealeii Eye Lenses To Determine Migratory Patterns In The Eastern Gulf Of Mexico Using Statoliths For Age Determination, Hannah M. Schwaiger

USF Tampa Graduate Theses and Dissertations

Doryteuthis (Amerigo) pealeii is a common fisheries squid that occurs in the Gulf of Mexico (GoM) and along the east coast of the United States. These squid are an important link in the food web, linking higher and lower trophic positions (Madsen et al., 2007), and they are also used for human consumption. The migration patterns of D. pealeii populations in the northwestern North Atlantic have been thoroughly studied when compared to those in the GoM. This research aims to combine statolith aging and stable isotope analysis to enhance the understanding of D. pealeii migration patterns throughout their short, sub-annual …

Characteristics And Hydraulic Behavior Of Adsorptive Media For Use In Permeable Reactive Barriers, Shelby Rocha

USF Tampa Graduate Theses and Dissertations

The Cargill ditch is located on the property of Se7en Wetlands, a 1600-ac treatment wetland system in Lakeland, Polk County, Florida. The Se7en Wetlands property was previously utilized for phosphate mining prior to the construction of the system. Nonpoint nutrient sources derived from remnants of abandoned phosphate mines – known as “legacy phosphorus” – become mobilized by stormwater runoff and impair surface water bodies by promoting harmful algal blooms (HABs). Thus, the Cargill ditch likely conveys nutrient rich flow resulting from legacy phosphorus and is thought to be one contributing factor in the occurrence of HABs within the treatment wetland …

Soft Contact Lens Tear Film Proteomics For Clinical Diagnostic Biomarker Discovery, Robert Kimball Roden

Theses and Dissertations

Human tear film is an accessible biospecimen rich with useful biological information. As tear protein biomarkers for both ocular and systemic diseases have been identified in tears, efforts are being made to create point-of-care tests useful for clinical diagnoses. However, there are significant obstacles to tear diagnostics, including inadequate sampling methods and biomarkers with insufficient sensitivity and specificity. Furthermore, tear film diagnostics are particularly challenging for dry eye disease (DED) patients, where low tear volume makes sampling more difficult and the multifactorial nature of DED makes identifying the exact pathological subtype very complex. As soft contact lenses (SCLs) are designed …

Reconstructing Historical Earthquake-Induced Tsunamis: Case Study Of 1852 Event Using The Adjoint Method Combined With Hmc, Chelsey Noorda

Theses and Dissertations

Seismic hazard analysis aims to estimate human risk due to natural disasters such as earthquakes. To improve seismic hazard analysis, our group is focused on earthquake induced tsunamis and the use of statistical models to reconstruct historical earthquakes. Based on the estimated wave heights given in anecdotal historical descriptions, we created observational probability distributions to model the historically recorded observations and constructed a prior distribution on the relevant earthquake parameters based on known seismicity of a given region. Then we used the software package GeoClaw, and a Metropolis-Hastings sampler to obtain a posterior distribution of earthquake parameters that most closely …

Investigating The Use Of Translational Methods To Characterize Therapeutic Interventions In Models Of Pulmonary Disease, Ashley Rae Chang

Theses and Dissertations

Idiopathic Pulmonary Fibrosis (IPF) is an interstitial lung disease with no known cause or cure. IPF has an incidence of 75/1,000,000 of the population, predominately in men over the age of 60. This relatively rare disease develops in a chronic and progressive way, ultimately leading to death within two to five years of diagnosis. Our use of translatable methodologies in the bleomycin mouse model of IPF led to the novel identification of the similarities between the average percent loss of lung function in previous human clinical trials to that of our mouse model data. There is no treatment for IPF …

Design, Synthesis And Immunological Testing Of Minimal Oligosaccharide Epitopes For Glycoconjugate Vaccines Targeting Capsular Polysaccharides Of Serotypes 3, 4, 7f And 9v Of Streptococcus Pneumoniae, Seth A. Taylor

Theses and Dissertations

The rise in antibiotic resistant strains of bacteria has led to the need for new methods of combatting bacterial infection. Since the surfaces of bacteria are covered in uniquely patterned capsular polysaccharides, vaccines targeting these polysaccharides have become a popular field of research for protection against pathogenic bacteria. Though licensed polysaccharide vaccines are commercially available, they lack the efficiency to protect patients that are immunocompromised or at high risk because they elicit T cell independent immune responses, resulting in low-affinity antibodies. To elicit a T cell dependent response and thereby recruit B cells that produce high-affinity antibodies, a vaccine was …

Investigation Of Challenging Transformations In Gold Catalysis, Qi Tang

USF Tampa Graduate Theses and Dissertations

This dissertation mainly contains three parts: 1) Divergent gold catalysis for alkyne trifunctionalization, encompassing three distinct modes to achieve the simultaneous formation of C-N, C-O, and C-C bonds in a single step 2) the study and development of a new method to synthesize azaborine derivatives; and 3) the construction of benzotriazole boranes (BTAB) as stable four-coordinate N-B heterocycles through gold-catalyzed alkyne hydroboration.

In the first part, alkyne trifunctionalization via divergent gold catalysis will be introduced. This novel approach involves a sequence of reactions that combine gold π-activation, vinyl gold nucleophilic addition, and gold (III) reductive elimination. By utilizing this methodology, …

Understanding The Flow Dynamics Of The Pearl River, Ms, Through Hydrodynamic Modeling, Nahruma Mehzabeen Pieu

Master's Theses

The Pearl River brings fresh water and nutrients into Lake Borgne regulating conditions for oyster growth in estuarine waters. However, there are no flow measurement stations installed on East Pearl or West Pearl either at the river outlets or after the upstream bifurcation of the Pearl. This study aims to model the Lower Pearl River to understand the flow dynamics in the major branches, and to determine the final outflow distribution into the Mississippi Sound, aiming to improve river forcing for ocean models studying estuarine dynamics of the Mississippi Sound.

Synthetic meandering bathymetry with updated banks is developed and applied …

Nutrient Optimization For Vegetable Production Under Decoupled Aquaponics Using Brackish Water, Salma Walid Hany Ahmed Abdelfattah

Theses and Dissertations

As the world moves to more sustainable agriculture methods in the agribusiness industry, decoupled aquaponics is recognized as one of the newest techniques currently being utilized to achieve more local food security. As the topic is still freshly new within the industry, a finite number of publications and studies have been made that address the topic hands-on with its many variables. Subsequently, in this paper, an experiment was conducted to assess the most optimized production conditions of both lacinato kale (Brassica oleracea var.palmifolia) and Swiss chard Bright Light (Beta vulgaris ssp. Cicla var. flavescens) plants through the utilization of a …

The Mobility Of Long-Lived Radioisotopes And Their Burial In The Marine Environment, Neil Redmond

Dissertations

Marine sediments record chemical signals that reflect past environmental conditions. It is important to establish how these signals are created and whether they may be altered over time so that they can be useful for reconstructing ocean history. Measurements of uranium isotopes are used as a novel proxy for sedimentary diagenetic processes (Chapter 2). Because ²³⁴U can be ejected from mineral lattice during the decay of ²³⁸U, it creates a pool of U in porewater that is potentially mobilized and then deposited elsewhere in the core. We found that alpha-recoiled ²³⁴U is sensitive to differences in sediment …

Exploring Surface Silanization And Characterization Of Thin Films: From Surface Passivation To Microstructural Characterization Of Porous Silicon/Silica, And Exploratory Data Analysis Of X-Ray Photoelectron Spectroscopy Images, Behnam Moeini

Theses and Dissertations

Surface chemistry plays a key role in science and technology because materials interact with their environments through their surfaces. Understanding surface chemistry can help alter/improve the properties of materials. However, surface characterization and modification often require multiple characterization and synthesis techniques. Silicon/silica-based materials are technologically important, so studying their surface properties can enable future advancements. In this dissertation, I explore surface modification and characterization of different types of Si/SiO2 thin films, including silicon wafers, fused silica capillary columns, and oblique angle sputtered Si/SiO2 thin films. In Chapters 2-5, I first present a method to rapidly silanize silica surfaces using a …

The Use Of Artificial Intelligence In Higher Education: A Study On Faculty Perspectives In Universities In Egypt, Farah S. Sharawy

Theses and Dissertations

Artificial Intelligence (AI) is an emerging technology that is transforming various aspects of society, including higher education. This paper examines faculty perspectives from five different institutions; The American University in Cairo (AUC), The German University in Cairo (GUC), The Arab Academy for Science and Technology (AAST), Ain Shams University, and Cairo University, on the use of AI in higher education in teaching and learning in Egypt, with all its challenges and resources available to support it, and how it can be used to achieve equity and accessibility. This research was conducted through a qualitative study using semi-structured one- on-one interviews …

Gold-Catalyzed Diyne-Ene Cyclization: Synthesis Of Hetero Polyaromatic Hydrocarbons And 1,2-Dihydropyridines, Jingwen Wei

USF Tampa Graduate Theses and Dissertations

Homogeneous gold catalysts are known as a powerful tool for selectively activating alkynes and are well-developed in the construction of C-C, C-N, and C-O bonds to form complex compounds that are widely used in pharmaceuticals, industries, agriculture, etc. The investigation of gold(I) catalysis on conjugated diyne (compounds having two acetylene groups) enriches the complexity of the bond construction and allows the building of interesting skeletons in organic synthesis. One typical kind of substrate, diyne-ene, has both a conjugated diyne part and a 1,6- enyne part. We developed a new methodology to allow its divergent synthesis to heterocycles.

This dissertation mainly …

Applications Of Seismic And Geodetic Data To Earthquake Hazard Research, Mahsa Afra

USF Tampa Graduate Theses and Dissertations

Being a part of a seismically active zone, including large and crowded cities such asTehran, Qazvin and Semnan, Central Alborz experiences many local earthquakes. Knowl- edge of crustal velocity structure in this area is thus necessary considering its economical and political importance, a large concentration of population, and relatively poor construc- tion practice which increases the earthquake risks in this region. In second chapter of this thesis, we aim at obtaining the 3D crustal velocity structure of the Central Alborz region in northern Iran using local earthquake tomography. We also validate anomalies inferred from our velocity model using an independent …

Microplastics Presence In Rhizophora Mangle Roots Throughout Fishponds And Open Coasts In Moloka'i, Hawaii, Mia Hackett

University Honors Theses

Microplastics (MP) are an emerging global contaminant that has drawn the attention of many researchers in the last few decades due to their growing environmental threats. Pieces of plastic smaller than 5 mm, they are specifically a high cause for concern in marine environments as their small size allows them to flow from inland into the ocean. Through this movement, MPs have been found in all marine ecosystems and ingested by hundreds of marine species often mistaking them for food. Labeled as one of the most threatened ecosystems, mangrove forests are already a large sink for a variety of contaminants …

The Effect Of Solution Parameters On The Interfacial Chemical Dynamics Of Early-Stage Corrosion, Brianna K. Rector

Electronic Thesis and Dissertation Repository

Corrosion is a key long-term degradation process for metallic components in nuclear industry infrastructure. Accurately predicting the corrosion rate of a component in its service environment is considered a grand challenge in the corrosion community. Corrosion is a multi-step electrochemical process, with elementary steps involving mass transfer across more than one stage. Due to the multi-step, multi-phase nature of corrosion systems, predicting corrosion behaviour over time is complex. Existing corrosion models can describe electron transfer and mass transport steps independently, under narrow sets of conditions or over a specified duration but cannot account for the changes that occur over time …

On Image Response Regression With High-Dimensional Data, Noah Fuerth

Major Papers

A recent issue in statistical analysis is modelling data when the effect variable

changes at different locations. This can be difficult to accomplish when the dimensions

of the covariates are very high, and when the domain of the varying coefficient

functions of predictors are not necessarily regular. This research paper will investigate

a method to overcome these challenges by approximating the varying coefficient

functions using bivariate splines. We do this by splitting the domain of the varying

coefficient functions into a number of triangles, and build the bivariate spline functions

based on this triangulation. This major paper will outline detailed …

On Maximum Likelihood Estimators For A Jump-Type Affine Diffusion Two-Factor Model, Jiaming Yin Mr.

Major Papers

We consider a jump-type two-factor affine diffusion model driven by a subordinator in the context of continuous time observations. We study the asymptotic properties of the maximum likelihood estimator (MLE) for the drift parameters. In particular, we prove the strong consistency and the asymptotic normality of MLE in the subcritical case. We also present some numerical illustrations to confirm the theoretical results. The main difficulty of this major paper consists in proving the ergodicity of the model in the subcritical case and deriving the limiting behavior of the process.

The Power Of (Virtual) Convergence: The Unrealized Potential Of Pair Programming And Remote Work, Mikayla Maki

University Honors Theses

Remote work is expensive. It can lead to isolation, miscommunications, and ossified organizations. These problems occur because of a synchronicity mismatch between how we need to communicate as humans, and what today's tools are capable of. This mismatch can be solved by the adoption of remote pair programming, as exemplified by the authors work at a startup (Zed). Pair programming provides the organic, synchronous, reciprocal interaction necessary to develop the sorts of relationships that remote firms currently lack.

Exploring The Relationship Between Green Space And Academic Performance, Audrey Demeaux

University Honors Theses

A growing body of literature is exploring the possibility that the presence of green spaces near schools can work to improve academic performance. Research to date on the relationship between green space and academic performance has shown mixed results. However, some see incorporating green spaces into school layouts as a key alternative strategy for improving academic achievement in the United States. This paper adds to the emerging discourse on the relationship between green space and academic achievement by using open-source data to conduct a regression analysis exploring the possible relationship between green space near K-12 schools and SAT scores in …

Addressing The Impact Of Time-Dependent Social Groupings On Animal Survival And Recapture Rates In Mark-Recapture Studies, Alexandru M. Draghici

Electronic Thesis and Dissertation Repository

Mark-recapture (MR) models typically assume that individuals under study have independent survival and recapture outcomes. One such model of interest is known as the Cormack-Jolly-Seber (CJS) model. In this dissertation, we conduct three major research projects focused on studying the impact of violating the independence assumption in MR models along with presenting extensions which relax the independence assumption. In the first project, we conduct a simulation study to address the impact of failing to account for pair-bonded animals having correlated recapture and survival fates on the CJS model. We examined the impact of correlation on the likelihood ratio test (LRT), …