Physical Sciences and Mathematics Commons^™

Is The Chesapeake Bay Browning?, Samantha Williamson, Jessie Turner

Knowledge and Creativity Expo

Brownification is when water bodies turn brown over time. It occurs due to high amounts of color-dissolved organic matter (CDOM). CDOM is organic material, such as decaying leaves and organisms, that leaches into the water column like tea. It absorbs ultraviolet and blue light more than red light, causing the water to appear brown. After comparing surveys from 1987 and 2018, scientists discovered the Adirondack lakes underwent brownification as they recovered from acid rain. However, while increased CDOM can signify an ecosystem’s recovery, it can also hinder seagrass growth. Although scientists have studied this phenomenon in lakes, estuaries have not …

Living Shorelines As A Solution To Saltwater Marsh Erosion, Elizjah Eddy, Richard Hale

Knowledge and Creativity Expo

In recent years, saltwater marshes fringing the Lafayette River, a tributary of the Elizabeth River, have experienced degradation in response to increased inundation and ocean energy . These marshes provide critical ecological and economic benefits to the City of Norfolk, and prioritizing their long term health and sustainability is an important challenge. An emerging restoration tactic involves enhancing marsh elevation through the application of dredge material that would otherwise require disposal offshore (known as thin-layer placement or TLP). An important first step in TLP projects is characterizing the textural and geochemical properties of the existing marsh sediment. The goal of …

How Much Does Shape Matter: Investigating The Impact Of Marine Particle Morphological Features On In-Situ Settling Velocities Using Pca And Various Ml Models, Huanqing Huang, Alexander B. Bochdansky

Knowledge and Creativity Expo

Particle settling velocity serves as an essential component in ocean biological pump, as it determines particle retention time in the water column. Stokes’ law has been widely used to predict particle settling velocities by particle size and excess density in aquatic environments. However, an increasing number of studies suggest that Stokes’ law fits poorly in the size-velocity relationship of observations on small oceanic particles. Here, we present a series of novel approaches to investigate the relative contribution of settling velocities by the particle shape and optical densities using machine learning (ML) models and principal component analysis (PCA), based on 3906 …

Human Subject Studies For The Alignment Of Llm-As-A-Judge Evaluation Metric For Science News, Gabriel Vega Osborne

Knowledge and Creativity Expo

Science news has become an important vehicle to disseminate scientific breakthroughs, discoveries, and technological innovations. With the advancement of large language models and related AI models, it is possible to automatically generate science news from scientific papers, extending the reader population from domain scientists to a broader scope. However, how to evaluate the quality of the generated news warrants research. Traditional token based metrics have been shown to fail to evaluate the semantics and nuances of science news. Inspired by the fact that a major goal of science news is to educate readers with new knowledge, we thus propose knowledge …

A. Vs. I In Ai: Is There A Threshold To "Engineered" Intelligence?, Joshit Mohanty

Engineering Management & Systems Engineering Faculty Publications

Despite artificial intelligence reshaping the world, its development generates uncertainties regarding future capabilities. AI simultaneously exists as an artifact of engineering design and as autonomous intelligence, creating an observer-participant feedback loop. This paper proposes that embodied AI faces a bandwidth-limited intelligence threshold T_h that it arises from B = min(C_sens,C_Act). However, Shannon capacity measures bits while intelligence operates on concepts, necessitating a dual-channel model separating physical bandwidth B_io from representational capacity B_rep. Intelligence emerges as multi-dimensional rather than scalar, with components exhibiting different bandwidth dependencies. Surpassing T_h requires either new sensing methods expanding B, enhanced representational frameworks, or reconceptualization within …

Aura: An Ai-Powered Multimodal Prototype For Adaptive Apraxia Of Speech Therapy And Communication Support, Omotayo Omoyemi, Rachel K. Johnson

Speech-Language Pathology Faculty Publications

Apraxia of Speech (AOS) is a motor speech disorder that significantly limits communication and requires intensive, long-term therapy. Access to consistent treatment is often constrained by shortages of speech-language pathologists, high costs, and limited opportunities for continuous monitoring outside clinical settings. Recent advances in Artificial Intelligence (AI) provide new opportunities to support scalable and personalized speech therapy.

This paper presents AURA (Adaptive Understanding and Relearning Assistant for Apraxia), a multimodal AI framework designed to support speech therapy, progress monitoring, and communication for individuals with AOS. The system integrates speech analysis, machine learning–based error detection, reinforcement learning for adaptive therapy, and …

Part Ii: Industrial Information Integration Review 2020-2025, Jinzhi Li

Information Technology & Decision Sciences Faculty Publications

Industrial Information Integration Engineering (IIIE) has become increasingly essential for improving operational efficiency and harmonizing heterogeneous industrial systems through advanced digital integration approaches. Fueled by rapid advancements in Industry 4.0 technologies—including digital twins, artificial intelligence, immersive interfaces, and IoT infrastructures—IIIE is substantially transforming traditional enterprise architecture and integration frameworks. This systematic review synthesizes recent developments and emerging trends, with particular attention to the accelerating adoption of digital twins and the deepening convergence between operational technologies (OT) and information technologies (IT) across multiple sectors. While notable progress has been made, significant challenges persist, especially in developing resilient integration architectures and fully …

Universe Without A Cause: A Reply To David Lu, Daniel Linford

Philosophy Faculty Publications

David Lu has recently argued that denying the Modified Causal Principle (MCP)—that if the universe began to exist, then it has a cause—leads to the conclusion that we likely inhabit an Omphalos universe, one that began recently with the appearance of age. Lu goes on to argue that if the universe is likely Omphalos, then independent measurements of the universe’s age are unlikely to agree. I offer three families of objections. First, Lu’s probabilistic reasoning faces technical challenges and, even if those challenges are overcome, cannot rule out an Omphalos universe. Second, I propose an alternative hypothesis that does so. …

Plastic Waste Imports & Coastal Litter: Evidence From Citizen Science Data, Rebecca L.C. Taylor, Hebe Williams, Shan Zhang

Economics Faculty Publications

Plastic waste is an internationally traded commodity, where importing countries recycle plastic waste into usable materials. However, there are concerns that the importation process creates plastic litter - a negative externality - in importing countries. While this concern has received much media and policy attention, quantifying the magnitude of this externality has been hindered by a lack of data on plastic litter across countries and over time. To this end, we use unconventional citizen science data on litter from Ocean Conservancy's International Coastal Cleanup, together with the United Nations Comtrade Database, to estimate the correlation between traded plastic waste and …

Eigenvalue Bound Preservation: Numerical Experiments On The 2d Q-Tensor Flow, Marcel C. Deguzman

Knowledge and Creativity Expo

We study the evolution of nematic liquid crystals in two dimensions using the Q-tensor model, a continuum framework that describes the orientational order of rod-like molecules via symmetric, traceless matrices. Focusing on the Landau-de Gennes energy and its associated gradient flow, we consider a reduced two-dimensional formulation in which the Q-tensor is fully described by two scalar functions. This reduction simplifies the system to a nonlinear, coupled PDE for the scalars, while preserving essential physical features. A key question is whether the eigenvalues of the Q-tensor remain within the physically admissible range under this flow. Building on a theoretical result …

A Macrocognitive Design Taxonomy For Simulation-Based Training Systems: Bridging Cognitive Theory And Human-Computer Interaction, Jessica M. Johnson

Virginia Digital Maritime Center (VDMC) Faculty Publications

Simulation-based training systems are increasingly deployed to prepare learners for complex, safety-critical, and dynamic work environments. While advances in computing have enabled immersive and data-rich simulations, many systems remain optimized for procedural accuracy and surface-level task performance rather than the macrocognitive processes that underpin adaptive expertise. Macrocognition encompasses higher-order cognitive processes that are essential for performance transfer beyond controlled training conditions. When these processes are insufficiently supported, training systems risk fostering brittle strategies and negative training effects. This paper introduces a macrocognitive design taxonomy for simulation-based training systems derived from a large-scale meta-analysis examining the transfer of macrocognitive skills from …

A Hybrid Response Surface Methodology And Machine Learning Framework For Quantifying Effects Of Physicochemical Parameters On Pfas Distribution, Harsh V. Patel, Jazmin Green, Hyoshin Park, Stephanie Luster-Teasley Pass, Renzun Zhao

Engineering Management & Systems Engineering Faculty Publications

Predicting PFAS adsorption across diverse adsorbents and environmental matrices remains challenging because adsorbent physicochemical properties, PFAS molecular descriptors, and operational conditions simultaneously influence adsorption. This study develops and evaluates a unified hybrid modeling framework that integrates Response Surface Model (RSM) with machine-learning algorithms to quantify how six key variables, surface area, Log K_ow, pH_pzc, pK_a, log dose, and log-initial concentration, affect PFAS distribution coefficients (Log K_d). A data set of more than 1000 adsorption observations spanning 15 PFAS compounds, multiple adsorbent types, and a broad operational range was compiled and preprocessed using …

Micro-Behavioral Analysis Of Online Shopping Patterns For Blind Users, Yash Prakash, Akshay Kolgar Nayak, Nithiya Venkatraman, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok

Computer Science Faculty Publications

While online shopping platforms provide convenience and autonomy to blind users, their non-visual interactions remain underexplored at a micro-behavioral level. Existing studies have primarily emphasized accessibility and usability challenges but have overlooked how fine-grained, screen reader-driven keystroke-level behaviors reflect users’ cognitive strategies. In this paper, we present the findings of a longitudinal study with 25 blind participants to examine their micro-behavioral patterns, using keyboard activity and screen reader logs on both familiar and unfamiliar e-commerce websites. We complemented this study with semi-structured interviews to contextualize the uncovered micro-behavioral patterns. Our results revealed patterns in how blind users draw upon cognitive …

Crossing The Theory Threshold: The Pedagogical Potential Of Generative Artificial Intelligence In Educational Research, Amanda Burbage, Jennifer L. Styron

EVMS School of Health Professions Faculty Publications

Purpose

This paper presents findings from an educational research graduate course in which generative artificial intelligence (AI) was incorporated to strengthen learners' understanding of threshold concepts related to theoretical frameworks. Medical and health professionals often struggle with the transition from a clinical role into the educational research role.

Methods

The study posits that the use of generative AI will help learners understand and apply theoretical frameworks beyond a superficial level, furthering their understanding, constructing new knowledge, and strengthening their ability to develop sound educational research studies. Journal and AI transcripts were analyzed for 37 participants.

Results

Open-ended codes were grouped …

First-Generation Medical School Applicants: A Quantitative Study Designed To Identify Areas Of Educational Support, Bethsabe Romero, Amanda K. Burbage

EVMS School of Health Professions Faculty Publications

First-generation (First Gen) students are unique medical school applicants. Due to their lived experience, they approach patient care by prioritizing trust, comfort and understanding. They have proven ability to overcome obstacles and were found to be more resilient than their continuing generation (Cont Gen) peers. Despite these notable attributes, they face unique challenges in gaining medical school acceptance. There are very few quantitative studies examining this student subpopulation, and our study identifies characteristics of first-generation medical school applicants while highlighting areas of needed support. This cross-sectional study used deidentified Application and Matriculating Student Questionnaire survey data that was obtained from …

Reply To: S. N. Katkuri Et Al. And H. Liu Et Al. On Early And Sustained Improvements In Sense Of Smell With Tezepelumab Treatment In Patients With Chronic Rhinosinusitis With Nasal Polyps (Waypoint), Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose

Department of Otolaryngology (ENT) Faculty Publications

[Introduction] We thank Dr. S. N. Katkuri, Dr. H. Liu, and their coauthors [1, 2] for their interest in our recent publication describing the improvements in loss of smell symptoms with tezepelumab versus placebo in patients with uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) in the WAYPOINT trial (NCT04851964) [3]. We are grateful for the authors' feedback on the clinical significance of the data presented and their appreciation of the consistency observed across a range of baseline clinical characteristic and demographic subgroups.

Use Of Tezepelumab For Chronic Rhinosinusitis With Nasal Polyps By Eosinophilic Endotype: Waypoint Post-Hoc Analysis, Shigeharu Fujieda, Nobuyoshi Otori, Joseph K. Han, Tadataka Yabuta, Claudia Chen, Claudio Marchese, Andrews Foster, Sandhia S. Ponnarambil, Yun Chan, Brian J. Lipworth

Department of Otolaryngology (ENT) Faculty Publications

Background

The phase 3 WAYPOINT study (NCT04851964) reported that tezepelumab improved outcomes in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), including nasal polyp size, nasal congestion, and sinonasal symptoms, and reduced the need for surgery and systemic corticosteroids (SCS).

Objective

To evaluate the efficacy and safety of tezepelumab across Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis-defined eosinophilic chronic rhinosinusitis (ECRS) subgroups.

Methods

Adults with severe CRSwNP were randomized to tezepelumab 210 mg or placebo every 4 weeks. Coprimary end points were the change from baseline to week 52 in total Nasal Polyp Score and the biweekly mean Nasal …

An Association Test For Ordinal Outcomes In Clustered Data With Informative Cluster Size, Hasika K. Wickrama Senevirathne, Sandipan Dutta

Mathematics & Statistics Faculty Publications

In cluster-correlated data, the number of observations in a cluster can be associated with the outcome from that cluster. This phenomenon is known as informative cluster size which can occur in cluster-randomized clinical trial data. Several studies have found that ignoring the issue of informative cluster size can produce biased results in the analysis of clustered data. Most of the existing methods for addressing informative cluster size are suited to continuous outcomes. However, ordinal outcomes and covariates are often encountered in clustered data obtained from large clinical studies. The existing methods for ordinal association testing in clustered data can produce …

Logistic-T Multinomial Mixture Model For Clustering For Microbiome Data, Wenshu Dai, Yuan Fang, Sanjeena Subedi

Mathematics & Statistics Faculty Publications

The logistic-normal multinomial distribution has been used for modelling microbiome data obtained from high-throughput sequencing technologies, which are compositional in nature. A logistic-normal multinomial distribution is a hierarchical multinomial distribution that assumes the latent variable which are the additive log-ratio (ALR) transformed proportions in a multinomial distribution follows a Gaussian distribution. Model-based clustering algorithms have also been developed for clustering microbiome data based on the logistic-normal models. However, the Gaussian assumption may violated when the ALR transformed variable exhibit heavy-tailed distributions or has outliers. Our study introduces a novel mixture of logistic-t multinomial models that effectively address these challenges. Utilizing …

Determining The Electric Field In A 10 Ns Pulsed Plasma In Fuel-Air Mixtures Using Efish, Md Ziaur Rahman, Christopher J. Kliewer, Brian D. Patterson, Chunqi Jiang

Bioelectrics Publications

Transient plasma ignition (TPI) utilizes non-equilibrium plasmas, produced by nanosecond high-voltage pulses, to improve lean-fuel combustion performance and reduce emission. It is known that the relatively high reduced electric field (E/N) in TPI plays an important role in generating energetic electrons and facilitating energy-efficient radical productions, resulting in reliable ignition for lean combustion. Determining the reduced electric field in the discharge is hence important for the understanding of the TPI process and ultimately allowing for the control of the plasma chemistry. This study reports spatiotemporally resolved measurements of the electric field (E) in a 10 ns pulsed plasma that is …

Ammonia Synthesis By Nanosecond Pulsed Atmospheric Pressure Plasma Jets Impinging On Water, Zach Caudell, Lynnet Rich, Olga Pakhomova, Chunqi Jiang

Bioelectrics Publications

Developing energy-efficient technologies for carbon-neutral ammonia (NH₃) synthesis is critical for decentralized fertilizer production and global decarbonization. This study investigates generating NH₃ from water using a nanosecond pulsed atmospheric pressure plasma jet (ns‑APPJ) operating in either N₂ or dry air. The plasma jet reactor employed approximately 250 ns, up-to-22 kV pulses at 500 Hz to sustain a nonequilibrium discharge impinging directly on static liquid water. The kinetics, energy efficiency, and product selectivity of NH3 formation were quantified as functions of the pulse voltage, repetition frequency (PRF), and gas flow rate. NH₃ production increased linearly with treatment time and scaled strongly …

Gaze Transition Entropy And Automation Trust In Multitasking Workspace, Yusuke Yamani, Austin Jackson, Tetsuya Sato, Feyishola Ashimi, Michael S. Politowicz, Eric T. Chancey, Makoto Itoh

Psychology Faculty Publications

Safe flight operation requires visual scanning across multiple displays in a cockpit, which collectively represent the state of the aircraft and supporting automation. Trust is a crucial factor that drives human-automation interaction, and recent work has suggested a relationship between an operator's visual attention and automation trust. One index that captures predictability of eye movements between different areas of interest is gaze transition entropy. The current work reanalyzed data from Sato et al., which examined eye movement patterns and trust in automation associated with the system monitoring task of the Multi-Attribute Task Battery. Results showed credible positive correlations between the …

Gradient-Based, Post-Optimality Sensitivity Analysis With Respect To Parameters Of State Equations, Gene Hou, Jonathan Degroff

Mechanical & Aerospace Engineering Faculty Publications

Design optimization is a computational tool that can enable a designer to investigate the effectiveness of a design concept in an organized format. However, this design process requires the design variables, constraints, and objective function to be properly defined and expressed in mathematical forms. Post-optimality analysis thus becomes a necessary step to investigate different variations in the problem formulation and parameters to ensure that optimization produces a stable and trustworthy outcome. One efficient way to achieve this aim is to compute the local derivative of the optimized objective function with respect to the optimization problem parameters, such as bounds on …

Uncertainty-Aware Estimation, Planning, And Control For Tracking Multiple Drifting Patches In Flow Fields, Daniel O. Akanji, Krishnanand N. Kaipa, Cong Wei

Mechanical & Aerospace Engineering Faculty Publications

In this study, we present a replay-based framework for uncertainty-aware persistent tracking of multiple advected surface patches using an autonomous marine vehicle operating in spatiotemporal-varying currents. The method combines three components: local flow estimation, covariance-aware patch-boundary propagation with intermittent boundary fusion, and mission-level scheduling over multiple patches. Each patch is represented by a polygonal boundary, whose vertices are propagated through the estimated flow field while carrying per-vertex covariance, thereby quantifying uncertainty growth during advection. A flow-aware gain-scheduled linear quadratic regulator (LQR) was designed to shape the desired surge speed to take advantage of favorable currents. When the vehicle services a …

Mechanical-Medical Convergence In Heart Failure: Artificial Intelligence, Finite-Element Modeling, And 3d Printing For Diagnosis And Prognosis, Quazi Noor E. Sabrina, Quazi Md Zobaer Shah, Quazi Noor E. Sohela, Md Mahabub Hasan Mousum, Md. Moyeen Uddin Chisty, Quazi Md. Akbar Shah

Mechanical & Aerospace Engineering Faculty Publications

Heart failure remains a leading cause of global morbidity and mortality, yet routine clinical indices often miss the regional biomechanical disturbances that drive progression and shape treatment response. This State-of-the-Art review examines how finite-element (FE) modeling, additive manufacturing, and artificial intelligence (AI) are converging to improve the diagnosis, phenotyping, procedural planning, and prognostic assessment of heart failure (HF). Although these technologies have matured in structural heart disease and transcatheter intervention research, their greatest translational potential may lie in HF, where patient-specific ventricular remodeling, myocardial stress–strain heterogeneity, valve-ventricular coupling, and device-tissue interaction are incompletely captured by conventional clinical indices. We synthesize …

Radical-Based Oxidative Pretreatment Enhances Biofuel Production From Lignocellulosic Biomass Via Hydrothermal Liquefaction, João Vitor Dos Santos, Louis C. Bondurant, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

The sustainable production of biofuels from lignocellulosic biomass is a central goal in the transition to low-carbon energy systems. However, hydrothermal liquefaction (HTL), a promising thermochemical conversion pathway, is constrained by the high oxygen content and complex aromatic structure of lignin, which lowers bio-oil quality. Here, we used a model system of brown-rot-degraded white oak (Quercus alba) to test whether radical-based oxidative pretreatment could enhance HTL performance by converting lignin into more aliphatic intermediates. Oxidation was performed under simulated Fenton conditions using fixed Fe(II) (60 ppm) and two hydrogen peroxide concentrations (3 and 8 M), resulting in extensive lignin depolymerization …

Twenty-One Years Of Global Atmospheric Chlorine Inventories From Atmospheric Chemistry Experiment Fourier Transform Spectrometer (Ace-Fts) Measurements, N. Raymond, P. Bernath, C. Boone, M. P. Chipperfield

Chemistry & Biochemistry Faculty Publications

We present atmospheric chlorine inventories over 21 years (2004-2024) and five latitude bands (82-60°N, 60-30°N, 30°N-30°S, 30-60°S, 60-82°S) across altitudes from the surface up to 61 km. These inventories were calculated using the Atmospheric Chemistry Experiment-Fourier Transform Spectrometer (ACE-FTS) version 5.3 retrievals of the volume mixing ratios (VMRs) of 13 chlorine-containing species. Of these, five are product gases: HCl, HOCl, ClONO₂, COClF, COCl₂, and eight are source gases: CCl₄, CH₃Cl, CFC-11 (CCl₃F), CFC-12 ( CCl₂F₂), CFC-113 (CClF₂CCl₂F}), HCFC-22 (CHF₂Cl), HCFC-141b ( C₂H₃Cl₂F), and HCFC-142b (C₂H₃}Cl₂F). Where necessary, ACE-FTS data were supplemented with data from the TOMCAT 3-D chemical transport model, …

Scanning Electron Microscopy As A Potential Tool For Distinguishing Charcoal From Dark, Oxidized, Biomass, João Vitor Dos Santos, Aleksandar I. Goranov, Lais Gomes Fregolente, Joao Marcos De Lima-Faria, Diego Stefani Teodoro Martinez, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

Condensed aromatic carbon (ConAC) is widely used as a proxy for organic materials derived from biomass burning. However, recent evidence shows that ConAC can be also formed through nonpyrogenic oxidative processes. This study presents a proof-of-concept investigation using scanning electron microscopy (SEM) to distinguish charcoal from dark, ConAC-rich materials produced by ambient oxidation of biomass. Pine wood exposed to long-term iron-mediated oxidation was compared with unaltered wood and a controlled laboratory-generated charcoal reference. Conventional geochemical analytical methods, including benzenepoly(carboxylic acid) (BPCA) analysis, Fourier transform–ion cyclotron resonance–mass spectrometry (FT-ICR-MS), solid-state 13C nuclear magnetic resonance (NMR) spectroscopy, and elemental analysis, confirmed substantial …

The Influence Of Scale In Modeling Social Vulnerability And Disaster Assistance, Sina Razzaghi Asl, Oronde Drakes, Eric Tate, Samuel Brody, Wesley Highfield, Kayode Atoba

Political Science & Geography Faculty Publications

Understanding how social vulnerability relates to disaster impacts is critical for addressing social equity, yet the role of spatial scale in this relationship is often overlooked. Most studies use aggregated data, risking ecological fallacy-misinterpreting individual outcomes from group-level data. This study examines how spatial scale influences the relationship between social vulnerability and federal disaster assistance after Hurricane Harvey. Using spatial econometric models at both household and census tract levels, we assessed the strength of key vulnerability indicators in explaining disaster assistance. Results show that disability, housing tenure, household size, and income predict assistance at the household level, but their influence …

Shaping The Future: Emerging Technologies And Their Role In Industry 4.0 And Beyond, Liuliu Qin

Information Technology & Decision Sciences Faculty Publications

This paper provides a comprehensive review of emerging technologies driving the transition from Industry 4.0 to Industry 5.0. It examines the foundational concepts and pillars of Industry 4.0 and explores the transformative roles of Artificial Intelligence (AI), Extended Reality (XR), Collaborative Cobots (Cobots), Brain–Computer Interfaces (BCIs), quantum technologies, and next-generation connectivity (5G/6G). By integrating technological, human-centric, and sustainability perspectives, the study outlines how these emerging technologies reshape industrial systems and enable intelligent, adaptive, and inclusive futures.