Physical Sciences and Mathematics Commons^™

Human Subject Studies For The Alignment Of Llm-As-A-Judge Evaluation Metric For Science News, Gabriel Vega Osborne

Knowledge and Creativity Expo

Science news has become an important vehicle to disseminate scientific breakthroughs, discoveries, and technological innovations. With the advancement of large language models and related AI models, it is possible to automatically generate science news from scientific papers, extending the reader population from domain scientists to a broader scope. However, how to evaluate the quality of the generated news warrants research. Traditional token based metrics have been shown to fail to evaluate the semantics and nuances of science news. Inspired by the fact that a major goal of science news is to educate readers with new knowledge, we thus propose knowledge …

The Ai Revolution In Virtual Try-Ons: A Means-End Chain Model Perspective, Ju-Young M. Kang, Ji Young Lee, Dooyoung Choi, Sumin Helen Koo, Jeehyun Song, Youngjin Bahng

Educational Leadership & Workforce Development Faculty Publications

Leading brands have begun to implement artificial intelligence-driven virtual try-on (AI VTO) technology, which helps reduce returns and increase conversion rates, repeat purchases, and customer loyalty. This research aimed to examine how retail user experience with specific perceived quality factors of AI VTOs influences users’ value equity and downstream loyalty and to investigate the moderating effects of clothing in relation to the self as structure and concern for physical appearance, based on a Means–End Chain model. Data were collected from 509 U.S. online apparel shoppers using a consumer panel. Structural equation modeling and multigroup analysis were used for data analysis. …

First-Generation Medical School Applicants: A Quantitative Study Designed To Identify Areas Of Educational Support, Bethsabe Romero, Amanda K. Burbage

EVMS School of Health Professions Faculty Publications

First-generation (First Gen) students are unique medical school applicants. Due to their lived experience, they approach patient care by prioritizing trust, comfort and understanding. They have proven ability to overcome obstacles and were found to be more resilient than their continuing generation (Cont Gen) peers. Despite these notable attributes, they face unique challenges in gaining medical school acceptance. There are very few quantitative studies examining this student subpopulation, and our study identifies characteristics of first-generation medical school applicants while highlighting areas of needed support. This cross-sectional study used deidentified Application and Matriculating Student Questionnaire survey data that was obtained from …

Multi-Grade Deep Learning, Yuesheng Xu

Mathematics & Statistics Faculty Publications

Deep learning requires solving a nonconvex optimization problem of a large size to learn a deep neural network (DNN). The current deep learning model is of a single-grade, that is, it trains a DNN end-to-end, by solving a single nonconvex optimization problem. When the layer number of the neural network is large, it is computationally challenging to carry out such a task efficiently. The complexity of the task comes from learning all weight matrices and bias vectors from one single nonconvex optimization problem of a large size. Inspired by the human education process which arranges learning in grades, we …

A New Functional Setting For Term Structure Modeling Using The Health-Jarrow-Morton Framework, Michael Pokojovy, Ebenezer Nkum, Thomas M. Fullerton Jr.

Mathematics & Statistics Faculty Publications

The well-known Heath–Jarrow–Morton (HJM) framework provides a universal and efficacious instrument for modeling the stochastic evolution of an entire yield curve by explaining the interest rate dynamics in continuous time under no-arbitrage conditions. Existing implementations involve exponentially weighted function spaces as theoretical settings for the former stochastic evolution. While the choice of weight can have a drastic effect on model calibration and subsequent forecasting, it cannot be estimated from market data and does not allow for any objective interpretation. The proposed approach does not have this shortcoming as it adopts a suitably designed unweighted function space. The HJM equation is …

Aura: An Ai-Powered Multimodal Prototype For Adaptive Apraxia Of Speech Therapy And Communication Support, Omotayo Omoyemi, Rachel K. Johnson

Speech-Language Pathology Faculty Publications

Apraxia of Speech (AOS) is a motor speech disorder that significantly limits communication and requires intensive, long-term therapy. Access to consistent treatment is often constrained by shortages of speech-language pathologists, high costs, and limited opportunities for continuous monitoring outside clinical settings. Recent advances in Artificial Intelligence (AI) provide new opportunities to support scalable and personalized speech therapy.

This paper presents AURA (Adaptive Understanding and Relearning Assistant for Apraxia), a multimodal AI framework designed to support speech therapy, progress monitoring, and communication for individuals with AOS. The system integrates speech analysis, machine learning–based error detection, reinforcement learning for adaptive therapy, and …

Part Ii: Industrial Information Integration Review 2020-2025, Jinzhi Li

Information Technology & Decision Sciences Faculty Publications

Industrial Information Integration Engineering (IIIE) has become increasingly essential for improving operational efficiency and harmonizing heterogeneous industrial systems through advanced digital integration approaches. Fueled by rapid advancements in Industry 4.0 technologies—including digital twins, artificial intelligence, immersive interfaces, and IoT infrastructures—IIIE is substantially transforming traditional enterprise architecture and integration frameworks. This systematic review synthesizes recent developments and emerging trends, with particular attention to the accelerating adoption of digital twins and the deepening convergence between operational technologies (OT) and information technologies (IT) across multiple sectors. While notable progress has been made, significant challenges persist, especially in developing resilient integration architectures and fully …

Supercharging Simulation-Based Inference For Bayesian Optimal Experimental Design, Samuel Klein, Willie Neiswanger, Daniel Ratner, Michael Kagan, Sean Gasiorowski

Physics Faculty Publications

Bayesian optimal experimental design (BOED) seeks to maximize the expected information gain (EIG) of experiments. This requires a likelihood estimate, which in many settings is intractable. Simulation-based inference (SBI) provides powerful tools for this regime. However, existing work explicitly connecting SBI and BOED is restricted to a single contrastive EIG bound. We show that the EIG admits multiple formulations which can directly leverage modern SBI density estimators, encompassing neural posterior, likelihood, and ratio estimation. Building on this perspective, we define a novel EIG estimator using neural likelihood estimation. Further, we identify optimization as a key bottleneck of gradient based EIG …

Identifying Relevant Covariates In Rna-Seq Analysis By Pseudo-Variable Augmentation, Yet Nguyen, Dan Nettleton

Mathematics & Statistics Faculty Publications

RNA-sequencing (RNA-seq) technology allows for the identification of differentially expressed genes, which are genes whose mean transcript abundance levels vary across conditions. In practice, RNA-seq datasets often include covariates that are of primary interest in addition to a set of covariates that are subject to selection. Some of these covariates may be relevant to gene expression levels, while others may be irrelevant. Ignoring relevant covariates or attempting to adjust for the effect of irrelevant covariates can compromise the identification of differentially expressed genes. To address this issue, we propose a variable selection method that uses pseudo-variables to control the expected …

Utilizing Machine Learning Techniques For Computer-Aided Covid-19 Screening Based On Clinical Data, Honglun Xu, Andrews T. Anum, Michael Pokojovy, Sreenath Chalil Madathil, Yuxin Wen, Md Fashiar Rahman, Tzu-Liang (Bill) Tseng, Scott Moen, Eric Walser

Mathematics & Statistics Faculty Publications

The COVID-19 pandemic has highlighted the importance of rapid clinical decision-making to facilitate the efficient usage of healthcare resources. Over the past decade, machine learning (ML) has caused a tectonic shift in healthcare, empowering data-driven prediction and decision-making. Recent research demonstrates how ML was used to respond to the COVID-19 pandemic. This paper puts forth new computer-aided COVID-19 disease screening techniques using six classes of ML algorithms (including penalized logistic regression, random forest, artificial neural networks, and support vector machines) and evaluates their performance when applied to a real-world clinical dataset containing patients’ demographic information and vital indices (such as …

A Macrocognitive Design Taxonomy For Simulation-Based Training Systems: Bridging Cognitive Theory And Human-Computer Interaction, Jessica M. Johnson

Virginia Digital Maritime Center (VDMC) Faculty Publications

Simulation-based training systems are increasingly deployed to prepare learners for complex, safety-critical, and dynamic work environments. While advances in computing have enabled immersive and data-rich simulations, many systems remain optimized for procedural accuracy and surface-level task performance rather than the macrocognitive processes that underpin adaptive expertise. Macrocognition encompasses higher-order cognitive processes that are essential for performance transfer beyond controlled training conditions. When these processes are insufficiently supported, training systems risk fostering brittle strategies and negative training effects. This paper introduces a macrocognitive design taxonomy for simulation-based training systems derived from a large-scale meta-analysis examining the transfer of macrocognitive skills from …

Advancing Food Equity Through Explainable Ai (Xai): Identifying Place-Based Factors And Conditions Of Food Security, Leslie Hoglund, Hyoshin Park

Health Behavior, Policy & Management Faculty Publications

Food behaviors, food security, and their association with socioeconomic factors constitute a critical area of study with implications for public health, economic stability, and social equity. Understanding these relationships are essential for developing effective policies and interventions that promote sustainable, healthy food systems and greater food equity. This paper employs explainable artificial intelligence (XAI) methods to identify key features influencing household food behaviors. The insights gained from the XAI analysis are further utilized in conjunction with inverse reinforcement learning (IRL) to examine expert behaviors related to eating habits satisfaction. The XAI results reveal that household health conditions, spending patterns, and …

Machine Learning: Thematic Feature Grouping, And The Magnificent Seven: A Forecasting Analysis, Mirarmia Jalali, Mohammad Najand, Andrew Cohen

Finance Faculty Publications

This study examines the predictability of monthly excess returns for the “Magnificent Seven” U.S. technology firms using machine learning and economically motivated thematic feature grouping. Framed as a focused study of the most systemically consequential equity panel in modern markets—seven firms representing over 30% of the S&P 500—the analysis confronts a small-N, large-P environment where economically structured dimensionality reduction is essential. Using 154 firm-level characteristics categorized into 13 economic themes, we evaluate linear, penalized, tree-based, and neural network models in a small-N, large-P setting. Unrestricted models suffer substantial overfitting and fail to outperform the historical average benchmark out-of-sample. In contrast, …

Natural Resource Rents And Energy Poverty Nexus In Next Eleven Economies, Muhammad Salah Uddin, Ayub Ali, Zobayer Ahmed, Md Nasir Uddin Sikdar, Ahsan Habib, Abdullah Elah Al-Mahde

Finance Faculty Publications

Energy poverty (EP) remains a persistent global challenge with important implications for economic development, public health, and social welfare. While natural resources, particularly oil and gas, are often viewed as key sources of energy access, their effectiveness in mitigating EP remains underexplored in emerging economies. This study examines the relationship between natural resource rents (NRR), specifically oil rents (OR) and natural gas rents (NGR), and energy poverty (EP) in the Next Eleven (N-11) countries from 2000 to 2020. The primary objective is to assess how NRR influences EP at various levels of poverty using the Method of Moments Quantile Regression …

A Hybrid Response Surface Methodology And Machine Learning Framework For Quantifying Effects Of Physicochemical Parameters On Pfas Distribution, Harsh V. Patel, Jazmin Green, Hyoshin Park, Stephanie Luster-Teasley Pass, Renzun Zhao

Engineering Management & Systems Engineering Faculty Publications

Predicting PFAS adsorption across diverse adsorbents and environmental matrices remains challenging because adsorbent physicochemical properties, PFAS molecular descriptors, and operational conditions simultaneously influence adsorption. This study develops and evaluates a unified hybrid modeling framework that integrates Response Surface Model (RSM) with machine-learning algorithms to quantify how six key variables, surface area, Log K_ow, pH_pzc, pK_a, log dose, and log-initial concentration, affect PFAS distribution coefficients (Log K_d). A data set of more than 1000 adsorption observations spanning 15 PFAS compounds, multiple adsorbent types, and a broad operational range was compiled and preprocessed using …

An Association Test For Ordinal Outcomes In Clustered Data With Informative Cluster Size, Hasika K. Wickrama Senevirathne, Sandipan Dutta

Mathematics & Statistics Faculty Publications

In cluster-correlated data, the number of observations in a cluster can be associated with the outcome from that cluster. This phenomenon is known as informative cluster size which can occur in cluster-randomized clinical trial data. Several studies have found that ignoring the issue of informative cluster size can produce biased results in the analysis of clustered data. Most of the existing methods for addressing informative cluster size are suited to continuous outcomes. However, ordinal outcomes and covariates are often encountered in clustered data obtained from large clinical studies. The existing methods for ordinal association testing in clustered data can produce …

Logistic-T Multinomial Mixture Model For Clustering For Microbiome Data, Wenshu Dai, Yuan Fang, Sanjeena Subedi

Mathematics & Statistics Faculty Publications

The logistic-normal multinomial distribution has been used for modelling microbiome data obtained from high-throughput sequencing technologies, which are compositional in nature. A logistic-normal multinomial distribution is a hierarchical multinomial distribution that assumes the latent variable which are the additive log-ratio (ALR) transformed proportions in a multinomial distribution follows a Gaussian distribution. Model-based clustering algorithms have also been developed for clustering microbiome data based on the logistic-normal models. However, the Gaussian assumption may violated when the ALR transformed variable exhibit heavy-tailed distributions or has outliers. Our study introduces a novel mixture of logistic-t multinomial models that effectively address these challenges. Utilizing …

Determining The Electric Field In A 10 Ns Pulsed Plasma In Fuel-Air Mixtures Using Efish, Md Ziaur Rahman, Christopher J. Kliewer, Brian D. Patterson, Chunqi Jiang

Bioelectrics Publications

Transient plasma ignition (TPI) utilizes non-equilibrium plasmas, produced by nanosecond high-voltage pulses, to improve lean-fuel combustion performance and reduce emission. It is known that the relatively high reduced electric field (E/N) in TPI plays an important role in generating energetic electrons and facilitating energy-efficient radical productions, resulting in reliable ignition for lean combustion. Determining the reduced electric field in the discharge is hence important for the understanding of the TPI process and ultimately allowing for the control of the plasma chemistry. This study reports spatiotemporally resolved measurements of the electric field (E) in a 10 ns pulsed plasma that is …

Ammonia Synthesis By Nanosecond Pulsed Atmospheric Pressure Plasma Jets Impinging On Water, Zach Caudell, Lynnet Rich, Olga Pakhomova, Chunqi Jiang

Bioelectrics Publications

Developing energy-efficient technologies for carbon-neutral ammonia (NH₃) synthesis is critical for decentralized fertilizer production and global decarbonization. This study investigates generating NH₃ from water using a nanosecond pulsed atmospheric pressure plasma jet (ns‑APPJ) operating in either N₂ or dry air. The plasma jet reactor employed approximately 250 ns, up-to-22 kV pulses at 500 Hz to sustain a nonequilibrium discharge impinging directly on static liquid water. The kinetics, energy efficiency, and product selectivity of NH3 formation were quantified as functions of the pulse voltage, repetition frequency (PRF), and gas flow rate. NH₃ production increased linearly with treatment time and scaled strongly …

Gradient-Based, Post-Optimality Sensitivity Analysis With Respect To Parameters Of State Equations, Gene Hou, Jonathan Degroff

Mechanical & Aerospace Engineering Faculty Publications

Design optimization is a computational tool that can enable a designer to investigate the effectiveness of a design concept in an organized format. However, this design process requires the design variables, constraints, and objective function to be properly defined and expressed in mathematical forms. Post-optimality analysis thus becomes a necessary step to investigate different variations in the problem formulation and parameters to ensure that optimization produces a stable and trustworthy outcome. One efficient way to achieve this aim is to compute the local derivative of the optimized objective function with respect to the optimization problem parameters, such as bounds on …

Uncertainty-Aware Estimation, Planning, And Control For Tracking Multiple Drifting Patches In Flow Fields, Daniel O. Akanji, Krishnanand N. Kaipa, Cong Wei

Mechanical & Aerospace Engineering Faculty Publications

In this study, we present a replay-based framework for uncertainty-aware persistent tracking of multiple advected surface patches using an autonomous marine vehicle operating in spatiotemporal-varying currents. The method combines three components: local flow estimation, covariance-aware patch-boundary propagation with intermittent boundary fusion, and mission-level scheduling over multiple patches. Each patch is represented by a polygonal boundary, whose vertices are propagated through the estimated flow field while carrying per-vertex covariance, thereby quantifying uncertainty growth during advection. A flow-aware gain-scheduled linear quadratic regulator (LQR) was designed to shape the desired surge speed to take advantage of favorable currents. When the vehicle services a …

Mechanical-Medical Convergence In Heart Failure: Artificial Intelligence, Finite-Element Modeling, And 3d Printing For Diagnosis And Prognosis, Quazi Noor E. Sabrina, Quazi Md Zobaer Shah, Quazi Noor E. Sohela, Md Mahabub Hasan Mousum, Md. Moyeen Uddin Chisty, Quazi Md. Akbar Shah

Mechanical & Aerospace Engineering Faculty Publications

Heart failure remains a leading cause of global morbidity and mortality, yet routine clinical indices often miss the regional biomechanical disturbances that drive progression and shape treatment response. This State-of-the-Art review examines how finite-element (FE) modeling, additive manufacturing, and artificial intelligence (AI) are converging to improve the diagnosis, phenotyping, procedural planning, and prognostic assessment of heart failure (HF). Although these technologies have matured in structural heart disease and transcatheter intervention research, their greatest translational potential may lie in HF, where patient-specific ventricular remodeling, myocardial stress–strain heterogeneity, valve-ventricular coupling, and device-tissue interaction are incompletely captured by conventional clinical indices. We synthesize …

Radical-Based Oxidative Pretreatment Enhances Biofuel Production From Lignocellulosic Biomass Via Hydrothermal Liquefaction, João Vitor Dos Santos, Louis C. Bondurant, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

The sustainable production of biofuels from lignocellulosic biomass is a central goal in the transition to low-carbon energy systems. However, hydrothermal liquefaction (HTL), a promising thermochemical conversion pathway, is constrained by the high oxygen content and complex aromatic structure of lignin, which lowers bio-oil quality. Here, we used a model system of brown-rot-degraded white oak (Quercus alba) to test whether radical-based oxidative pretreatment could enhance HTL performance by converting lignin into more aliphatic intermediates. Oxidation was performed under simulated Fenton conditions using fixed Fe(II) (60 ppm) and two hydrogen peroxide concentrations (3 and 8 M), resulting in extensive lignin depolymerization …

Twenty-One Years Of Global Atmospheric Chlorine Inventories From Atmospheric Chemistry Experiment Fourier Transform Spectrometer (Ace-Fts) Measurements, N. Raymond, P. Bernath, C. Boone, M. P. Chipperfield

Chemistry & Biochemistry Faculty Publications

We present atmospheric chlorine inventories over 21 years (2004-2024) and five latitude bands (82-60°N, 60-30°N, 30°N-30°S, 30-60°S, 60-82°S) across altitudes from the surface up to 61 km. These inventories were calculated using the Atmospheric Chemistry Experiment-Fourier Transform Spectrometer (ACE-FTS) version 5.3 retrievals of the volume mixing ratios (VMRs) of 13 chlorine-containing species. Of these, five are product gases: HCl, HOCl, ClONO₂, COClF, COCl₂, and eight are source gases: CCl₄, CH₃Cl, CFC-11 (CCl₃F), CFC-12 ( CCl₂F₂), CFC-113 (CClF₂CCl₂F}), HCFC-22 (CHF₂Cl), HCFC-141b ( C₂H₃Cl₂F), and HCFC-142b (C₂H₃}Cl₂F). Where necessary, ACE-FTS data were supplemented with data from the TOMCAT 3-D chemical transport model, …

Scanning Electron Microscopy As A Potential Tool For Distinguishing Charcoal From Dark, Oxidized, Biomass, João Vitor Dos Santos, Aleksandar I. Goranov, Lais Gomes Fregolente, Joao Marcos De Lima-Faria, Diego Stefani Teodoro Martinez, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

Condensed aromatic carbon (ConAC) is widely used as a proxy for organic materials derived from biomass burning. However, recent evidence shows that ConAC can be also formed through nonpyrogenic oxidative processes. This study presents a proof-of-concept investigation using scanning electron microscopy (SEM) to distinguish charcoal from dark, ConAC-rich materials produced by ambient oxidation of biomass. Pine wood exposed to long-term iron-mediated oxidation was compared with unaltered wood and a controlled laboratory-generated charcoal reference. Conventional geochemical analytical methods, including benzenepoly(carboxylic acid) (BPCA) analysis, Fourier transform–ion cyclotron resonance–mass spectrometry (FT-ICR-MS), solid-state 13C nuclear magnetic resonance (NMR) spectroscopy, and elemental analysis, confirmed substantial …

Shaping The Future: Emerging Technologies And Their Role In Industry 4.0 And Beyond, Liuliu Qin

Information Technology & Decision Sciences Faculty Publications

This paper provides a comprehensive review of emerging technologies driving the transition from Industry 4.0 to Industry 5.0. It examines the foundational concepts and pillars of Industry 4.0 and explores the transformative roles of Artificial Intelligence (AI), Extended Reality (XR), Collaborative Cobots (Cobots), Brain–Computer Interfaces (BCIs), quantum technologies, and next-generation connectivity (5G/6G). By integrating technological, human-centric, and sustainability perspectives, the study outlines how these emerging technologies reshape industrial systems and enable intelligent, adaptive, and inclusive futures.

Universe Without A Cause: A Reply To David Lu, Daniel Linford

Philosophy Faculty Publications

David Lu has recently argued that denying the Modified Causal Principle (MCP)—that if the universe began to exist, then it has a cause—leads to the conclusion that we likely inhabit an Omphalos universe, one that began recently with the appearance of age. Lu goes on to argue that if the universe is likely Omphalos, then independent measurements of the universe’s age are unlikely to agree. I offer three families of objections. First, Lu’s probabilistic reasoning faces technical challenges and, even if those challenges are overcome, cannot rule out an Omphalos universe. Second, I propose an alternative hypothesis that does so. …

How Should Ai Talk About Us? Llms And Social Generics, Tiffany A. Zhu

Philosophy Faculty Publications

How should AI-generated speech balance epistemic aims, such as precision and accuracy, with ethical and social considerations? This paper examines a subtle yet consequential aspect of LLM-driven communication: the use of generic generalizations that convey information about social groups (e.g., “immigrants work low-wage jobs”). While central to human epistemic and pedagogical practices, generics are theorized to reinforce stereotypes, essentialism, and injustice. Using ChatGPT-3.5 as a case study, I uncover tendencies for AI chatbots to inconsistently hedge and refuse generics, including those that reflect well-documented social structural patterns, such as “women are more likely to get attacked while walking alone at …

Improving Medical Diagnostics With Vision-Language Models: Convex Hull-Based Uncertainty Analysis, Ferhat Ozgur Catak, Murat Kuzlu, Taylor Patrick, Michel Audette

Engineering Technology Faculty Publications

In recent years, vision-language models (VLMs) have been applied to various fields, including healthcare, education, finance, and manufacturing, with remarkable performance. However, concerns remain regarding VLMs' consistency and uncertainty, particularly in critical applications such as healthcare, which demand a high level of trust and reliability. This paper proposes a novel approach to evaluate uncertainty in VLMs' responses using a convex hull approach on a healthcare application for visual question answering (VQA). For any VLM, temperature refers to a sampling parameter used in probabilistic generation, which controls the randomness of the model's output. The LLM-CXR model is selected as the medical …

Bridging The Knowledge-Practice Gap In Breast Cancer Awareness: A Nationwide Online Cross-Sectional Kap Study Among Adult Females In Nigeria, Madinat Hassan, Taofeek Tope Adegboyega, Bilkisu Usman Farouk, Sunday Zeal Bala, Rachael Olufunmilayo Oduyemi, Kazeem Owolabi, Munir Sani, Miracle Uwa Livinus, Hannatu Usman Ayuba, Sadiq Hassan, Ifeyinwa Maureen Okeke, Abednego Shekari, Murtala Jibril

Chemistry & Biochemistry Faculty Publications

Background and Aims

Breast cancer (BCa) is a major cause of cancer morbidity and mortality among women in Nigeria, with late presentation contributing to poor outcomes. This study assessed knowledge, attitudes, and willingness to perform breast self-examination (BSE) among adult females in Nigeria and examined associated factors.

Methods

We conducted a descriptive cross-sectional online survey between February 16 and April 30, 2024. A structured, pretested questionnaire was disseminated through digital platforms, yielding 711 consenting adult female respondents from all six geopolitical zones. Knowledge, attitude, and willingness-to-perform-BSE measures were analyzed using descriptive statistics, linear regression, and binary logistic regression. Associations were …