Physical Sciences and Mathematics Commons^™

Purification And Investigation Of Bromelain Enzyme From Pineapple, Elsie J. Dahnert, Leah O. Hanson, Regan E. Stafanoni, Reyna Olson, Eion D. Hinkle, Muaj-Infinite S. Yang

Research & Creative Achievement Day

Bromelain proteins are a group of digestive protease enzymes that act as a chemical defense to prevent grazing. Bromelain is often taken as a dietary supplement in an attempt to support digestion, and it is used as a meat tenderizer in the restaurant industry. Extracting Bromelain from pineapple, especially the skin, leaves, and stem of the plant, can create a value-added product from what is widely considered to be agricultural waste. In this research, we examined the difference in Bromelain concentrations between the flesh of the pineapple and the skin, leaves, and stem of the pineapple, and the efficacy of …

A Sticky Situation: Mannose Glycosides, Morgan Romanski, Scott Hasty

2026 Student Academic Showcase

Mannose chemistry is notoriously difficult due to the electronic structure of the molecule. The dipole moments on the molecule provide stability, meaning adding and removing substituents come with many obstacles. This results in numerous byproducts, prevents reactions from going quickly, or prevents the reaction from occurring at all. In this project, the issue of producing a mannose molecule with the desired leaving group for glycosylations is investigated using two different methods of synthesis of attaching 2-mercaptopyridimine to a benzylated mannose on carbon 1. These two methods investigate and aim to solve the issue of epoxide formation and the mannose molecule …

Complete Synthesis Of A Beta-Linked Disaccharide, Abby Dunn

2026 Student Academic Showcase

The continual need to develop strategies and methods for oligosaccharide synthesis drives carbohydrate chemists to discover new glycosides. This push has led to the discovery of an attractive 6-methylpyrid-2-yl leaving group for chemical glycosylation. Presented are three syntheses of the molecules 2-mercapto-6-methylpyridine, glycosyl donor 6-methylpyrid-2-yl-2,3,4,6-O-acetyl-1-thio-β-D-glucopyranoside, and glycosyl acceptor methyl-2,3,4-O-benzyl-α-D-glucopyranoside. The 2-mercapto-6-methylpyridine molecule was affixed to the requisite sugar to produce the glycosyl donor, 6-methylpyrid-2-yl-2,3,4,6-O-acetyl-1-thio-β-D-glucopyranoside. This sugar was then coupled with methyl-2,3,4-O-benzyl-α-D-glucopyranoside using silver triflate (AgOTf) to obtain the targeted disaccharide.

Synthesis, Structural Elucidation, In Vitro Antibacterial Activity Of Mononuclear Ag(I) Complex Derived From (E)-N-(4-Fluorophenyl)-1-(Pyridin-2-Yl) Methanimine And Triphenylphosphine Ancillary Ligand., Olufemi Stephen Odulaja, Saliu Alao Amolegbe, Muritala Adeniyi Olusola

Tanzania Journal of Science

Chemo-therapeutic application of metal complexes to remediation and subjugation of emerging infectious diseases with a view to improving potency and efficacy of a variety of drugs is gaining more momentum, especially in the 21st century. This research work designed a new biologically active complex [AgL(PPh3)2]NO3,C, obtained from the reaction of Ag(I) nitrate with bidentate pyridinyl Schiff base ligand (E)-N-(4-fluorophenyl)-1-(pyridin-2-yl) methanimine L, with triphenylphosphine (PPh3) as co-ligand. Characterisation was done by FT-IR, UV-Vis, NMR, (TGA/DTA), X-ray crystallography, and elemental analysis. The combined effects of pyridinyl Schiff base ligand and PPh3 on the antibacterial activities against Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, …

Investigating The Substrate Specificity Of Azo Bond Reduction In The Human Gut Microbiome, Najoude Claude, Annick Kenfack, Glorimar De Los Santos, Madeline Bormes

Chemistry & Biochemistry Student Scholarship

The bacteria of the human gut microbiome can metabolize drugs, often causing unintended side effects. The uniqueness and variability of each individual’s microbial composition, coupled with our limited understanding of specific enzyme functions, make the metabolic outcomes of these therapeutics difficult. Azoreductase enzymes are of particular interest due to their ability to reduce azo bonds, which are often found in drugs and food dyes. Azo dyes can also be reduced nonenzymatically by hydrogen sulfide, a bacterial metabolite produced during sulfate and cysteine metabolism. The goal of this study is to examine the specificity and relative kinetics of both enzymatic and …

Vanadium’S Journey From Essential Trace Metal To Emerging Environmental Pollutant In The Anthropocene Era, Tanu Arora, Nivedita Agnihotri, Mohammad Azam

Turkish Journal of Chemistry

Vanadium, previously considered a minor trace element, is gaining global environmental attention due to its expanding applications in metallurgy, energy storage, catalysis, and agriculture. With this rise in its industrial and technological uses, however, anthropogenic emissions of vanadium into the atmosphere, soils, and water bodies have also escalated. Unlike many heavy metals, vanadium exhibits complex redox behavior, primarily existing as V(IV) and V(V) species, which significantly impacts its environmental mobility, bioavailability, and toxicity. Vanadium exhibits complex behavior that necessitates an integrated research approach to better understand its various roles in scientific fields. This review summarizes the current knowledge on vanadium’s …

Computational And Experimental Analysis Of Oleanolic Acid As An Allosteric Activator Of Sirt1, Emrah Sariyer, Eda Dokumacioğlu, Hati̇ce İskender

Turkish Journal of Chemistry

Sirtuin 1 (SIRT1) is a member of the sirtuin protein family and the biological effects of SIRT1 encompass various areas such as the ageing process, metabolism regulation, and cellular stress response. SIRT1 activators are compounds that enhance the activity of SIRT1 enzyme. These activators can be natural or synthetic compounds and have the potential to provide health benefits by augmenting the biological effects of SIRT1. Oleanolic acid (OA) is a triterpenoid compound that has antiinflammatory, antioxidant, and glucose and lipid metabolism-regulating properties naturally found in many plants. The aim of the present study was to investigate the effect of OA …

Synthesis Of Werner- And Werner-Like-Type Clathrates, Their Characterization, And Theoretical Calculation Of Their Properties, Zari̇fe Si̇bel Şahi̇n, Zeki̇ Kartal

Turkish Journal of Chemistry

In this paper, the synthesis and structural characterization of three new coordination compounds in crystal structure consisting of a nickel atom, varying numbers of 3-aminopyridine molecules, and two isothiocyanate ion ligands are presented. The crystal structures of these compounds were determined by single crystal X-ray diffraction. Consequently, the explicit formulas and shorthand notations of the compounds are [Ni(NCS)2(C5H6N2)2(H2O)]·(H2O) (1), [Ni(NCS)2(C5H6N2)3]·(C2H6) (2), and [Ni(NCS)2(C5H6N2)4]·2(C5H6N2) (3). The consistency of the crystal structure data was confirmed by elemental analysis and infrared spectroscopy. These coordination compounds are Werner-like-type clathrates containing water, ethane, and 3-aminopyridine molecules as guest molecules in their structures, respectively. According to …

Influence Of Precursor Synthesis Temperature And Hydrothermal Alkaline Medium On Agglomeration And Crystal Phase Of Barium Titanate Nanoparticles, Murat Özen

Turkish Journal of Chemistry

Phase‑pure, cube‑like barium titanate (BaTiO3) nanoparticles were synthesized via hydrothermal treatment of a single‑source barium-titanium peroxo-hydroxide precursor. Precursor solutions prepared at room temperature, 0 °C, and –10 °C with various storage times exhibited Ba/Ti molar ratios ranging from 0.66 to 1.05 as determined by X-ray fluorescence. Cooling the precursor solution to –10 °C effectively suppressed the polymerization of Ti-O-Ti, yielding near‑ideal stoichiometry and finer precursor particles. Subsequent hydrothermal processing in NH4OH, KOH, and NaOH (0.5–10 M, 100–200 °C) revealed the strong dependence of agglomeration and morphology on the alkaline medium. While NH4OH and KOH resulted in severe agglomeration and the …

Sensitive Stripping Voltammetric Determination Of An Anthracene–Isatin Schiff Base In Biological Samples, Gökçe Öztürk, İrem Gökgöz, Emi̇ne Arslan, Eli̇f Şi̇şman, İnci̇ Seli̇n Doğan, Di̇lek Kul, Fatma Ağin

Turkish Journal of Chemistry

​In the present study, the electrochemical behavior and quantitative determination of the Schiff base 3-[(anthracen-2-yl)imino]-5-nitro-1,3-dihydro-2H-indol-2-one (ANT) were investigated for the first time using voltammetric techniques at a glassy carbon electrode. The effects of solvent composition, pH, and scan rate on the redox behavior of ANT were systematically evaluated. The compound exhibited an irreversible oxidation process governed by adsorption-controlled kinetics. Quantitative analysis was conducted using differential pulse stripping voltammetry (AdS-DPV) and square-wave stripping voltammetry (AdS-SWV) under optimized conditions. Both methods exhibited linear responses over the concentration range of 0.2–8.0 μM, with limits of detection of 0.0366 μM and 0.0433 μM for …

Investigation Of The Enzyme-Inhibitory, Antibacterial, And Anticancer Properties Of Metal Phthalocyanines, Meryem Topal, Fevzi̇ Topal, Firat Yilmaz, Esra Bulut Atalay, Ümi̇t Muhammet Koçyi̇ği̇t, Emre Güzel

Turkish Journal of Chemistry

In this study, the enzyme inhibitory, antibacterial, and anticancer activities of a phthalonitrile derivative and its metal phthalocyanines (Pcs; indium, zinc, copper, cobalt, and manganese; 1–6) were investigated. The cobalt and manganese Pcs were synthesized for the first time in this study. The inhibitory activities of the symmetric Pcs, which were expected to interact with acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) via their 4-(isopropylbenzyl)oxy substituents through host–guest interactions, were investigated. More selective inhibition of AChE than BChE was observed for these compounds. For AChE, CoPc was identified as the most potent inhibitor (IC50 = 14.81 nM), whereas for BChE, InPc was …

Templating Effect Of Neutral Dithiane Ligands On The Self-Assembly Of Cationic Au(I)-Phosphine Units, Farzane Osanlou, Abdollah Neshat, Mohammad Reza Yousefshahi, Vaclav Eigner, Michal Dusek, Shahram Seidi

Turkish Journal of Chemistry

The interactions between the dinuclear Au(I) precursor (dppm)Au2Cl2 and neutral sulfur-containing dithianes (specifically 1,3- and 1,4-dithiane) were examined in the presence of NH₄PF₆. Although these sulfur-based ligands were initially employed to facilitate the formation of mixed phosphine/sulfur Au(I) complexes, single-crystal X-ray diffraction analysis revealed the unexpected generation of multinuclear Au(I) assemblies exclusively coordinated by phosphine ligands. When 1,3-dithiane was present, a trinuclear Au(I) complex was isolated, characterized by a central four-coordinate Au(I) center exhibiting a distorted see-saw geometry, flanked by two terminal Au(I) centers with T-shaped coordination environments. Importantly, the dithiane ligand did not coordinate directly to the gold centers …

Nucleophilic Cyclization Of N-Propargylated Pyrazole-5-Carboxylates: Synthesis Of Pyrazolo[1,5-A]Pyrazin-4(5h)-One Derivatives, Meli̇k Firat Mengeş, Meltem Tan Uygun

Turkish Journal of Chemistry

Cyclization reactions are among the most important and widely used methods for synthesizing biologically active fused heterocyclic compounds. In the present study, pyrazolopyrazinone derivatives (10a–i) were synthesized from N-propargylated pyrazoles via nucleophilic cyclization with hydrazine hydrate under a nitrogen atmosphere. Nuclear magnetic resonance (NMR) spectral analyses confirmed that ring closure proceeded in a manner consistent with the formation of a six-membered pyrazinone moiety. In addition, the pyrazolotriazepinone derivative 15c was synthesized using an alternative approach. In this method, substitution with chloroacetone was first carried out, followed by ring closure with hydrazine hydrate, affording a seven-membered triazepinone system. Comparison of the …

The Synthesis And Evaluation Of Thioxothiazolidin-4-One Compounds As Pim Kinase Inhibitors, Kelly Malzewski

Master's Theses (2009 -)

The Proviral integration site for Moloney Murine Leukemia virus (PIM) kinases belongs to the family of serine/threonine kinases consisting of three isoforms; PIM1, PIM2, PIM3. PIM kinase is involved in multiple cellular processes through the phosphorylation of several proteins within the JAK/STAT pathway, leading to cell proliferation, apoptosis inhibition, cell migration, transcription, and energy metabolism. However, disruption or overexpression of PIM within the cycle can have negative, tumorigenesis effects with increased fatality rates. Currently, there are no FDA approved PIM kinase inhibitors available for specific cancer target therapies, despite the growing need and high demand research interests. It is widely …

Robust Thermodynamic Analysis Of Flexible Protein-Ligand Binding Using Statistical Mechanics, Mitchell Dulaney

Create@State

Understanding how proteins bind small molecules is essential for accurate computational modeling of biological systems. However, calculating binding free energy (delta G), enthalpy (delta H), and entropy (delta S) becomes unreliable when proteins are flexible, and ligands are between multiple binding positions. This motion causes traditional computational methods to produce inconsistent thermodynamic values.

A computational workflow was implemented that included docking to predict likely binding positions, molecular dynamics simulations to sample how the protein and ligand move over time, and statistical mechanics analysis to calculate thermodynamic quantities. A new theoretical framework was developed and implemented in a custom program to …

Synthesizing Fluorescent 3,4-Dihydropyrimidin-2(1h)-Ones Using A One-Pot Synthesis Reaction, John R. Griggs

Create@State

In medical and pharmaceutical practices, Biginelli (3,4-dihydropyrimidin-2(1H)-ones) products have a number of potential uses due to their anticancer and anti-inflammatory properties.  In addition, they are a possible treatment for acquired immunodeficiency syndrome (AIDS). These compounds can be further modified to exhibit fluorescent properties. However, before using them in medicinal studies, it is useful to establish a procedure that can easily be modified and is synthetically accessible to allow for further optimization. The experiment was performed using the Biginelli compounds as a substrate, along with a variety of aromatic aldehydes and acids. After obtaining the products and purifying them with vacuum …

Laser Ablation-Atomic Absorption Spectroscopy Of Yttrium Plasma, Dawn Gipson

Create@State

Laser ablation is a widely used sampling method for elemental chemical analysis. Laser-induced breakdown spectroscopy (LIBS) and laser ablation inductively-coupled mass spectrometry (LA-ICP-MS) are the two most common implementations. Application of these techniques is found throughout the sciences, including analysis in archaeological settings, geology, and medical analysis of hard tissue such as teeth or bone. Many applications benefit from the microdestructive nature of the technique. However, the relationship between the laser-ablation crater and the analytical signal is poorly understood. Laser ablation-atomic absorption spectroscopy (LA-AAS) is used in our laboratory to determine the mass of material incorporated into the plasmas in …

Synthesis And Characterization Of Thiazole Derivatives As Potential Antitumor Agents, Kaylee Leddy

Create@State

Melanoma is the 5th most common cancer in both men and women in the USA. It originates in melanocytes, which make the melanin pigment that gives skin its color. While treatable in early stages, melanoma becomes nearly incurable once metastasized. Thiazole derivatives have been recognized in many pharmaceutical classes including anticancer, antimicrobial, antimalarial, anti-tuberculosis, and diuretics. They have long been researched for their natural pharmacological properties and have shown potential to inhibit melanoma cell growth. In this study, catechol-substituted thiazole derivatives were synthesized using the Hantzsch-Thiazole synthesis. A total of 13 novel compounds were made using 2-chlorodihydroxyacetophenone with various catechol-substituted …

Uptake And Fate Of Silver And Zinc Engineered Nanoparticles In Maize Under Single And Binary Dosing Soil Ecosystems, Lei Xu, Qingbo Yang, Xingmao Ma, Honglan Shi, John Yang, Hu Yang, Samira Mahdi, Ying Wang, Young Shin Jun

Chemistry Faculty Research & Creative Works

Recent agricultural applications of engineered metallic nanoparticles (ENPs) have raised concerns about their uptake and fate in plants. To understand this critical issue, this study investigated the fate and uptake of silver (Ag) and zinc oxide (ZnO) ENPs in maize (Zea mays L.) after single or binary ENP exposure in soil. Results indicated that both Zn and Ag elemental concentrations in roots increased with increasing ENP dosage. Ag NPs in the tissues were detected, but not Zn NPs. Ag NP concentration was 3 times higher in the roots than in the shoots at low Ag NP dosing, while Ag NP …

Simulation And Projection Of Glaciers And Their Runoff In Xinjiang Based On Tgsgs, Zhongqin Li, Yefei Yang, Bowen Liu, Huilin Li, Zexin Zhan, Feiteng Wang, Chunhai Xu, Weibo Zhao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Glaciers are large flowing ice bodies formed from snowfall in cold regions. Due to the intrinsic physical properties of ice and the complexity of boundary conditions, physically based modelling of glacier change remains a global challenge. With support from the Chinese Academy of Sciences’ key science infrastructure program for the field station, the Tianshan Glaciological Station completed the Tianshan Glacier Station Glacier Simulator (TGSGS) in 2025. TGSGS features advanced representations of the physical mechanisms driving glacier change and multi-scale ensemble strategy, and is integrated with a reference glacier observation network based on terrestrial laser scanning (TLS), a low-temperature laboratory for …

Organic Synthesis Of A Hydrazine Functionalized Ammonium Compound For Improved Capture Of Aldehyde Metabolites From Exhaled Breath, Po'iu N. Burgo

Undergraduate Theses

Breath analysis has emerged as a non-invasive and inexpensive way to screen for respiratory diseases. This technique involves measuring concentrations of specific metabolites found in exhaled breath that serve as a biomarkers for disease. A subclass of volatile organic compounds called α,β-Unsaturated aldehydes, products of the lipid peroxidation mechanism, are underrepresented as biomarkers of lung cancer. These have been found to have relatively increased concentrations in the exhaled breath of lung cancer patients compared to a healthy patient. One of the reasons that these metabolites have been underreported is that the techniques used to measure and characterized exhaled metabolites do …

Techno-Enviro-Economic Analysis Of Precipitated Calcium Carbonate Production From Carbon Dioxide In Cement Industry Flue Gas And Calcium Hydroxide, Natalia Debora Panggabean, Widodo Wahyu Purwanto

Journal of Materials Exploration and Findings

CCUS is a technological solution to reduce emissions from the cement industry, which is the second largest CO2-intensive industry. This study aims to analyze technical, economic, and environmental performance of Precipitated Calcium Carbonate (PCC) synthesis in cement industry flue gas. The process simulation includes the CO2 capture system from cement plant, CO2 captured used as feedstock for PCC synthesis process through its reaction with calcium hydroxide. The simulation was carried out using ASPEN Plus software. Technical analysis was performed to determine the CO2 capture efficiency and PCC synthesis efficiency. Economic analysis was conducted to calculate CO2 capture cost and production …

Feasibility Analysis Of Thermal Oxidizer To Determine Remaining Life Using Fitness- For-Service Level 3 Method, Yudhi Yudistirawan, Donanta Dhaneswara, Wahyuaji Narottama Putra, Gama Widyaputra, Dewi Kurnia Suci, Agung Putra Mahardhika

Journal of Materials Exploration and Findings

An aged thermal oxidizer (TOX) in the oil and gas industry necessitates a comprehensive evaluation to ensure its continued safe operation. This study presents a Remaining Life Assessment (RLA) and a Fitness for Service (FFS) evaluation for the four main components of the TOX, in accordance with API 510, API 579/ASME FFS-1, and ASME BPVC Section VIII Div-1 standards. The investigation includes the determination of maximum stress and maximum temperature required to assess the operational viability of the reactor. The four components are radiant, convection, transition, and stack sections—were modeled using the finite element method (FEM). Following the geometric modeling, …

Assessing Passenger Electric Vehicle Growth Strategies And Their Impacts On Electricity Demand Load And Co2 Emissions In Aceh Province To Achieve Net Zero Emission Target By 2060, Taufik Hidayat, Widodo Wahyu Purwanto

Journal of Materials Exploration and Findings

The electrification of the transport sector is a crucial pathway for achieving Indonesia’s Net Zero Emissions (NZE) target by 2060. This study assesses the potential impact of passenger electric vehicle (EV) penetration on electricity demand and CO2 emissions in Aceh Province through a scenario-based modelling approach. Two policy-aligned scenarios are assessed: a low-penetration (LP) scenario and a high-penetration (HP) scenario. Using the Gompertz model and the ASIF framework, total CO2 emissions were projected from 2020 to 2060. Results show that although higher EV penetration reduces direct emissions from internal combustion engine (ICE) vehicles, total CO2 emissions increase more significantly under …

Czts Nanoparticles As Cost Efficient Catalysts For Producing Green Hydrogen, Aidan Hau

Undergraduate Research Symposium (2026- )

Hydrogen gas is produced to be used as feedstock, fertilizer, and fuel. Traditional hydrogen production produces “gray hydrogen” in a process that uses and releases fossil fuels into the atmosphere. One way to produce “green” hydrogen is with renewable energy technologies that produce hydrogen gas using electrolysis without emitting fossil fuels. In electrolysis, the hydrogen atoms bonded to oxygen in a water molecule are split to produce hydrogen. A typical catalyst for this process would be a precious metal like palladium, which can be costly. In order to make green hydrogen production more affordable, an alternative catalyst composed of CZTS …

Uhplc-Ms/Ms-Based Method Development And Validation For Multiclass Pesticide Residues In Food: Risk Assessment And Water Remediation, Muhammad Usman

Thesis/ Dissertation Defenses

The increasing use of pesticides in agriculture necessitates the development of sensitive and reliable analytical methods for accurate detection, risk assessment, and remediation. This dissertation focuses on the development and validation of advanced UHPLC-MS/MS-based methodologies for the determination of multiclass pesticide residues and their metabolites in complex food matrices, along with the remediation of organophosphorus pesticides in aqueous systems. Efficient sample preparation techniques, including liquid–liquid extraction (LLE) and QuEChERS-based dispersive solid-phase extraction, were optimized to reduce matrix interferences and enhance analytical performance. The developed methods were validated according to international guidelines (SANTE/11312/2021) and demonstrated excellent performance. Recoveries ranged between 70–120%, …

Quantum Scattering Of Hc5n And Para-H2 On A New Potential Energy Surface, Shan Gao, François Lique, Ernesto Quintas-Sánchez, Richard Dawes, Jérôme Loreau

Chemistry Faculty Research & Creative Works

In the interstellar medium (ISM), non-local thermodynamic equilibrium situations are common due to low density, and one needs to consider the effect of molecular collisions in order to interpret the observations. Among the species detected in the ISM, cyanopolyynes, with the general molecular formula HC_2n+1N (n = 1, 2, …), are characterized by large dipole moments and small rotational constants and constitute an indispensable class of candidates for the sensitive tracers of local density and temperature. We present a study of the collisional (de-) excitation of HC₅N by para-H₂ (p-H₂) in its ground …

Electroenzymatic Cascades For Nitrogen Upgrading: Beyond Ammonia Towards Value-Added Nitrogen Chemicals, Rohit G. Jadhav, Vamshi Krishna Kamaja, Wassim El Housseini, Monica Brachi, Shelley D. Minteer

Chemistry Faculty Research & Creative Works

The global transition toward sustainable chemical manufacturing demands technologies that leverage natural carbon and nitrogen cycles while minimizing reliance on sacrificial reagents and fossil resources. These biogeochemical cycles are fundamental to life, and enzymes catalyze many of their key transformations. Bio electrochemical, specifically electroenzymatic, systems offer a promising route to sustainable synthesis by enabling selective redox transformations powered by electricity. However, whereas carbon-cycle enzymes are now well established in bio electrochemical synthesis, enzymes from the nitrogen cycle remain comparatively underexplored. Moreover, the nitrogen cycle alone does not access many value-added nitrogen-containing products, which require additional C-N bond formation and organic …

The Impact Of An Interactive Open Education Textbook For An Undergraduate Introductory Chemistry Course For Nonmajors, Erin Avram

Chemistry Faculty Publications

Reading informational text is a critical skill across most professions. Unfortunately, students are less likely to purchase the required course materials now compared to 2010. A free, interactive text was developed for an introductory chemistry course for non-STEM majors. This involved remixing existing texts and incorporating interactive activities to engage students during the learning process and provide opportunities for them to gauge their learning. Based on the results of a student survey, 82% of students reported that it was very important to them that the text was free and 80% of students who responded reported that they used the eText …

The Efficacy Of Manganese Sulfate As A Negative Contrast Agent For Magnetic Resonance Cholangiopancreatography, Zainab Abdulla Mankhi

Karbala International Journal of Modern Science

The current study aims to find an alternate oral contrast media for use in magnetic resonance cholangiopancreatography (MRCP) that satisfies the following criteria, the greatest imaging quality safety, no or few side effects, and low cost. The present study created an oral contrast agent sample (solution) by dissolving a one tablet of manganese sulfate supplement (taken daily dose) in 200 ml of distilled water. Thirty-three volunteers assessed the sample using MRCP examine pre and post contrast. By evaluating the signal intensity to compute contrast (C), signal to noise ratios (SNR), and contrast to noise ratio (CNR), the resulting MR images …