Biopsychosocial Case Report, David F. Lo, Gaurav Kumar, Don D. Shamilov

Rowan-Virtua Research Day

Ms. R, a 32-year-old Hispanic female, suffers from severe anxiety exacerbated by a car accident and past struggles with depression and substance use. Evaluation reveals hypothyroidism, mild anemia, and GAD as the primary diagnosis. Factors contributing to her condition include genetic predispositions, medical issues, and social stressors. Treatment involves pharmacotherapy, psychotherapy, and monitoring her physiological health. Research on wearable data for GAD severity offers potential insights for her treatment. A holistic approach, considering biological, psychological, and social factors, guides her tailored treatment plan for overall well-being.

Alpha 7 Nicotinic Acetylcholine Receptor Expression In The Hippocampus Of Patients With Schizophrenia, Shruti Varshney, Ananya Nethikunta, Minjal Patel, Mary Kosciuk, Randel L. Swanson, Venkat Venkataraman, Robert Nagele, Eric Goldwaser, Nimish K. Acharya

Rowan-Virtua Research Day

Background: Schizophrenia (SZ) is a heterogenous psychiatric condition characterized by disruptions in cognition, social activity, affect, and perception often associated with a varied combination of positive and negative symptoms. The pathophysiology behind SZ remains poorly elucidated. Earlier reports have cited the importance of the alpha 7 nicotinic acetylcholine receptors (α7nAChR) in the hippocampus and the receptor’s association with auditory sensory gating and cognitive function. Specifically, variations in the expression and functionality of α7nAChR can be linked to auditory hallucinations experienced by patients with SZ and several therapies have been researched that target α7nAChRs. However, there are very few primary research …

Functional Stereotyping Of Women’S Self-Objectification As A Function Of Life History And Body Fat, Vienne Howay

Psychological Science Undergraduate Honors Theses

Individuals prioritize different goals as a function of stability in their environment, oftentimes leading people to prioritize reproduction in hostile ecologies. From this shift in priorities, perceivers could develop heuristics about how women may attempt to attract mates. Previous research suggests that higher levels of body fat are more attractive to men with a fast life history. With this awareness of men’s preferences in body fat, high-fat women from hostile ecologies could be expected to engage in more self-objectifying behavior in the service of mate attraction or attempting present themselves as objects of affection to men. This study tasked participants …

A Systematic Review Of Mental Health Of Women In Fragile And Humanitarian Settings Of The Eastern Mediterranean Region, Fauziah Rabbani, Aysha Zahidie, Amna Siddiqui, Sanam Shah, Zul Merali, Khalid Saeed, Mohamed Afifi

Brain and Mind Institute

Background: The increasing emergencies and humanitarian challenges have worsened the mental health condition of women in the Eastern Mediterranean Region.

Aim: To assess the prevalence, determinants and interventions to address mental health among women in fragile and humanitarian settings in the Eastern Mediterranean Region.

Methods: Using the Preferred Reporting Items for Systematic Review and Meta-analysis guidelines, we reviewed 59 peer-reviewed published studies (PubMed, IMEMR) and grey literature (WHO/IRIS) from January 2001 to February 2023, focusing on women's mental health in the Eastern Mediterranean Region. We then conducted a descriptive analysis of the sociodemographic characteristics.

Results: Among …

Validation Of A Novel Heritable Rodent Model Of Drug Abuse Vulnerability In Psychosis And Investigation Of Therapeutic Targets, Loren D. Peeters

Electronic Theses and Dissertations

Schizophrenia is a severe neuropsychiatric disorder of largely unknown etiology that is often accompanied by high rates of cigarette smoking, reduced quit success, and high relapse rates. Dysregulated dopamine signaling and aberrant synaptic plasticity in the mesocorticolimbic pathway are implicated in the pathophysiology of schizophrenia and conferred substance abuse disorder and relapse vulnerability. Genetic factors are presumed to play a significant role in the development of schizophrenia, with a 40-50% concordance rate for monozygotic twins, although genetic markers are inconsistent. As such, epigenetic factors have instead been implicated. Specifically, there is strong evidence to suggest DNA methylation at several candidate …

Comparative Analysis Of Acceptance And Commitment Therapy’S Effectiveness In An Intensive Outpatient Program Setting, Efrain Frank Ellin Iii

Electronic Theses and Dissertations

This thesis presents a comparative analysis of acceptance and commitment therapy (ACT) and treatment as usual (TAU) within an intensive outpatient program setting, evaluating their effectiveness in enhancing various dimensions of psychological well-being. Guided by two main research questions, the study investigates whether ACT demonstrates greater or equal effectiveness compared to TAU and if it provides more immediate effects on psychological well-being within three weeks. Utilizing a quasi-experimental design, the research incorporates a comprehensive array of measurement tools to assess outcomes related to anxiety, depression, stress, psychological flexibility, cognitive flexibility, emotion regulation, mindfulness self-efficacy, and life satisfaction among participants. The …

Single Case Experimental Design Examining Cognitive Behavioural Therapy For Post-Stroke Depression, Liam Alexander Mackenzie Myles, Emma Jones

Journal of Mind and Medical Sciences

Background. Post-stroke depression (PSD) is common in older-age adults and is typically treated with cognitive-behavioural therapy (CBT). However, research has ascertained mixed findings regarding the efficacy of CBT for PSD in older-age adults, with limited evidence in people from global majority backgrounds. Materials and Methods. This case study used single case experimental design methodology to examine the effectiveness of CBT for PSD in a black, older-age man. The effects of health conditions, cohort beliefs, transitions in role investments, socio-cultural context and early experiences on the client’s thoughts, emotions, physical sensations and behaviours were formulated, before behavioural activation was used to …

Syndrome Or Symptoms? Assessing Cothymia, Neuroticism And Lifetime Comorbidity In A Sample Of Psychiatric Patients, Fiammetta Iannuzzo, Fabiana Fiasca, Antonella Mattei, Carmela Mento, Maria Catena Silvestri, Fabrizio Turiaco, Rocco Antonio Zoccali, Maria Rosaria Anna Muscatello, Antonio Bruno

Journal of Mind and Medical Sciences

Background. Cross-sectional and longitudinal psychiatric comorbidity rates could represent a syndromic process rather than the co-occurrence of different disorders. ‘Cothymia’, the concomitant presence of depression and anxiety symptoms, and the ‘neuroticism’ dimension have been proposed as candidate vulnerability factors for psychiatric disorders trajectories. Based on this background, the present research was aimed at assessing the role of cothymia and neuroticism as syndromic processes in lifetime psychiatric disorders, and examining homotypic or heterotypic trends in the diagnostic continuum of comorbid mental disorders. Materials and methods. Data collection was carried out retrospectively through the consultation of medical records at the Psychiatry Unit …

Medication Assisted Therapy And First Episode Psychosis: Evaluating Treatment And Readmission Rates, Kayla Sherea Williams Bsn, Rn, Hannah Lee Brenner Bsn, Rn, Madison Makenzie Yount Bsn, Rn, Jacqueline Sharp Dnp, Aprn, Pmhp-Bc

Doctor of Nursing Practice Projects

Background The Centers for Disease Control and Prevention (CDC) found that each day more than 140 U.S. residents die from drug overdoses, specifically due to opioids. Due to this, alternatives were created to reduce overdoses and ensure safety. Medication assistance therapy (MAT) is an effective form of treatment for people with substance use disorders and is defined as the use of medication in conjunction with counseling or therapy for the treatment of substance use disorders. The efficacy of MAT is used adjunctively with psychotropic medications compared to using no MAT and using psychotropic medications alone with individuals who are experiencing …

The Effects Of Adverse Childhood Experiences On The Weight And Emotional Stability In Adolescents, Lauren Parayno

Nursing | Student Research Posters

Adverse childhood experiences (ACES)a r e traumatic events that can occur during an adolescent's life. Af e w example of ACES are: • parental divorce/ separation • having a parent or guardian that isaddicted to a substance. These events cause the adolescent tolive through a state of chronic stress. Furthermore, these experiences put adolescents at a greater risk for obesity and depression. With adequate screening, nurses would be able to identify adolescents going through these troubling times. Interventionssuch aseducation on a healthier lifestyle and providing counseling services, would be beneficial to the age group.

The Alexander Technique Applied To Dance And The Choreographic Process: Freeing Physical Expression From Trauma-Based Tension, Julia Johnston

Senior Honors Theses

Ballet, contemporary, and modern dancers have expressed incurring trauma during their training and professional dance experiences; in a 2020 survey, 41% of professional dancers and 30% of ballet students reported experiencing or witnessing sexually inappropriate behavior in their respective workplaces and schools (DDP). This is just one example of a potential source of trauma for dancers. The physiological effects of trauma cause physical effects, creating tension in a dancer’s body. Dance relies on physical expression, the expression of thought and feeling through movement, to connect with the audience. Trauma-based tension inhibits a dancer’s range of physical expression and connection to …

The Media’S Influence On Disordered Eating And Body Dysmorphia In Males And Females, Alexis Kotanidis, Jamie Vitrano

Molloy Multidisciplinary Undergraduate Research Conference

The media typically refers to various means of communication that reach or influence people widely. This includes television, radio, newspapers, magazines, social media platforms, websites, podcasts, and more. Essentially, it has many ways through which information is transmitted to a large audience. The media plays a significant role in shaping public opinion, especially with regard to disordered eating and body dysmorphia in both men and women. Disordered eating refers to a wide range of irregular eating behaviors that may or may not meet the criteria for a specific eating disorder diagnosis such as anorexia nervosa, bulimia nervosa, or binge-eating disorder. …

Implementing Universal Adult Depression Screening In A Rural Maine Free Medical Clinic, Karen Hussion

Doctor of Nursing Practice Scholarly Projects

Abstract

BACKGROUND: Depression in adults is a leading cause of disability, morbidity and mortality worldwide with an estimated prevalence of 20% in the US population. Despite estimates that one out of every five Americans suffers from depression, less than 50% of adult primary care patients with depression are identified, and less than 5% of all adult primary care patients are screened. To increase early detection and management of depression, the United States Protective Service Task Force (USPSTF) recommends routine depression screening for adults older than 18 years in primary care settings.

LOCAL PROBLEM: This project site was a rural, free, …

Depression And Other Risk Factors Of Suicide, Mckenna Newnam, Jaeyong Choi

Criminal Justice Student Work

Substance abuse, other mental disorders, and individual characteristics all play a role in the risk of suicide when concurrent with depression. Far more research exists on depression as it effects suicide alone. Future research needs to focus on depression as it effects suicide and explore the other possible factors that can impact the outcome. Understanding the different aspects of depression as it effects suicide will provide a template for scholars and individuals involved in the mental health system to enhance treatment.

Lai Antipsychotics Vs. Oral Antipsychotics: Treatment Adherence, Relapses, And Readmissions, Natalie N. Lewis Bsn, Rn, Mallory F. Johnson Bsn, Rn-Bc, Tyler N. Halle-Todd Bsn, Rn, Natalie N. Ragland Bsn, Rn, Sharon H. Little Dnp, Aprn, Fnp-Bc, Jacqueline Sharp Dnp, Aprn,Pmhnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background

Schizophrenia is a lifelong illness with recurrent and often debilitating symptoms that may impair daily functioning, cognition, behaviors, socialization, emotions, and expression. It is recognized as a global mental health burden that affects the individual, their family, and society. Medication nonadherence and resulting relapse detrimentally affect the patient’s physical and mental health and quality of life. They are associated with increased hospitalization and emergency room visits, substance use, suicide, and homelessness. Current guidelines endorse second-generation antipsychotics such as Risperidone and Aripiprazole as the first-line treatment for most cases of psychosis. However, long-acting injectable (LAIs) atypical antipsychotics are a promising …

Current Awareness And Tools Available For Stress-Induced Ibs In Children, Tripta Rughwani

Harrisburg University Dissertations and Theses

Introduction: Irritable Bowel Syndrome (IBS) is a gastrointestinal (GI) disorder that affects 13-38% of children (4-17 years) worldwide. Early life stresses like trauma, family pressure, abuse, and parenting factors may alter the HPA axis leading to GI sensitivity. IBS symptoms can impact an individual’s quality of life, affect school attendance, and can be emotionally and financially stressful for the caregivers. To date, there is no known cure for IBS. While antidepressants have shown some efficacy in treating moderate to severe IBS in adults, prescribing a universal antidepressant drug, especially to the pediatric population is challenging due to the variability …

The Dark Triad, Creativity And Morality, Erin Beers

Honors Theses

The Dark Triad of personality is the combination of narcissism, Machiavellianism, and psychopathy. The associative theory of creativity involves the default mode network of the brain, which is responsible for memory tasks, imagination, and thoughts of self. Since the Dark Triad traits involve inhibitory control and imagination, there is a high likelihood that observed alterations in these processes may be used to predict dark creativity patterns. Malevolent creativity involves using new ideas to complete tasks that will harm others. With creativity not being limited to positive outcomes, aspects of morality are also part of the creative decision-making processes. Morality is …

Interdisciplinary Treatment Approach To Youth With Intellectual Or Developmental Disabilities And Co-Occurring Mental Health Conditions, Ashley Greenwald, Erika Ryst, Diane D. Thorkildson, Lauren Brown

Developmental Disabilities Network Journal

Many individuals with Intellectual and/or Developmental Disabilities (IDD) have co-occurring mental health needs, yet service delivery options often do not allow for the integrated delivery of mental health treatment and social behavioral support services. Siloed treatment approaches often result in lack of collaboration between providers, increasing the difficulty in accessing comprehensive and coordinated treatments and reducing treatment potential and effective outcomes. Additionally, many service providers in behavioral support services are not trained to address significant mental health needs; similarly, providers of mental health services lack experience in modifying practices for differing cognitive needs. The lack of cross-training and cross-collaboration makes …

An Exploration Of Self-Reported Training Needs For Anxiety Interventions Among Primary Care Behavioral Health Consultants, Katherine Buckheit, Ryan Willard, Kyle Possemato, Robyn Shepardson, Abigail Lashinsky, Jen Funderburk

The Journal of Integrated Primary Care

Introduction: Despite the need for greater training in evidence-based interventions for the treatment of anxiety in primary care behavioral health (PCBH), there are limited data on which interventions are desired by behavioral healthcare consultants (BHCs). The objective of this study was to identify which interventions BHCs desired more training in when treating anxiety in PCBH practice, and to examine if this preference was associated with theoretical orientation. Method: We conducted an online survey of PCBH providers regarding their training preferences for treatment of anxiety symptoms. The final sample comprised 291 BHCs recruited from e-mail listservs of national professional organizations. Providers …

Implementation Of A Standardized Suicide Screening Process In A University Student Health Clinic: A Quality Improvement Project, Addie Grace Strong, Kathryn Dambrino, R. David Phillippi, Linda Wofford

DNP Projects

Background: Suicide is a leading cause of death among college age students, prompting the need for evidence-based screening tools like the Columbia Suicide Severity Rating Scale (C-SSRS) to enable early detection and timely intervention. Inconsistencies in suicide screening may pose a risk of missed intervention opportunities. This Doctor of Nursing Practice project specifically aimed to improve the quality and consistency of suicide screening in a university student health clinic by implementing the C-SSRS tool into the clinic workflow during mental health appointments. Methods: Employing a quality improvement framework, this scholarly project followed the Institute for Healthcare Improvement Model for Improvement …

Individual Differences In Cannabis Use Disorder With Implications For Endocannabinoid Modulation In Therapeutics Development, Erin L. Martin

MUSC Theses and Dissertations

Cannabis use disorder (CUD) is increasingly prevalent in the United States, but there is no effective pharmacological means to treat it. The endocannabinoid (eCB) system has emerged as a candidate therapeutic target demonstrating some evidence of efficacy in treating CUD. However, clinical trials evaluating eCB-modulating therapeutics have historically undervalued individual differences that could contribute to variation in treatment outcome (e.g. sex, comorbid psychiatric illness). To address this gap in the literature, the present set of studies (a) compared plasma eCB tone in groups underrepresented in treatment trials for CUD (females, individuals with comorbid major depressive disorder; MDD/CUD) with males or …

Prevalence And Severity Of Adhd Among Children With Second-Hand Smoke Exposure – A Us Population-Based Study, Saral R. Desai, Edward Lin

Tower Health Research Day

No abstract provided.

The Revolutionary St. Louis Insane Asylum, Julia Talbert

Undergraduate Research Symposium

Even with its grand structure on Arsenal Street towering over the city below, few residents of St. Louis and surrounding areas are aware of the grand history or even existence of the St. Louis Insane Asylum. The building is over 150 years old and was a place of hope, failure, strife, and empathy. The asylum had a large impact on St. Louis and provided revolutionary outlooks, unique perspectives, and curious therapies.

We Can Walk Together: Motivational Interviewing In Helping Professions, Nathan E. Purdue

SACAD: Scholarly Activities

Psychotherapists and researchers alike reasonably express ambivalence in the extant literature concerning its effectiveness. On one hand, psychotherapists can feel relief that the more than 500 theoretical paradigms that exist are statistically effective in their treatment. On the other hand, research consistently indicates that the existence of evidence-based treatments have not decreased the prevalence of common psychological problems such as major depressive disorder. Barriers to treatment abound, and motivation/adherence to treatment protocols may be a difficult process for a patient suffering through a psychosocial quandary. Additionally, psychological disorders inherently have perpetuating behaviors that may impede or attenuate treatment progress. Motivational …

Adolescent Marijuana Use And The Contribution To The Development Of Schizophrenia, Jocelyn Spandikow

Psychology Student Papers and Posters

Schizophrenia is an often debilitating mental condition that has become a popular topic of psychological research in recent years. Current research examines the correlation between drug use, genetics, and environment on the development of schizophrenia. Research looks at the structure of the brain in individuals with and without schizophrenia. However, research has failed to look at the specific correlation between marijuana use in adolescent youth and the developmental impact on the brain, including in the development of schizophrenia. The legalization of many recreational drugs, including marijuana, has come to fruition in recent years. This has raised concerns over adolescent access …

A Longitudinal Study Of The Development Of Social Anxiety In Young Autistic Children, Gillian K. Marshall

Senior Theses

Social anxiety is a prevalent anxiety disorder marked by fear and discomfort in social situations where scrutiny or evaluation by others is anticipated. This thesis investigates the interplay between social anxiety and autism spectrum disorder (ASD), a neurodevelopmental condition characterized by social and communication challenges. Individuals with ASD often face heightened levels of anxiety, intensifying their social difficulties and impeding their social development. Early identification of social anxiety symptoms, particularly in ASD children, is crucial for timely intervention and improved outcomes. However, diagnosing social anxiety in preschool-aged children, especially those with ASD, presents challenges due to the complexity of symptoms …

The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease, Noah Al-Hassan, Taha Al Hassan, Juan C. Lopez-Alvarenga, Maria Quinones, Seratna Guadarrama

Research Symposium

Background: Periodontal disease (PD), affecting 20-50% of the global population is marked by biofilm-induced inflammation in oral tissues. Chronic PD results in systemic complications such as heart disease, stroke, and Alzheimer's. The red complex microbes, Porphyromonas gingivalis and Treponema denticola, play a pivotal role, penetrating the blood-brain barrier and contributing to neurodegeneration. Alzheimer's disease (AD), an irreversible neurodegenerative disorder, is linked to abnormal protein cleavage and potentially involves microbiologic components, including gram-positive cocci. Research suggests the presence of bacteria such as Porphyromonas, Actinomyces, and Treponema in autopsied AD brains. Investigating the microbiologic connection between PD and AD is crucial, considering …

Emotional Support Animals And Mental Health, Kyla E. Barnett, Kaia Miller

SACAD: Scholarly Activities

Depression and anxiety disorders are a significant problem in adults and teenagers. These disorders continue to increase in prevalence year by year. One way to combat this is the use of emotional support animals (ESA’s), which have become increasingly popular. This study investigates the relationship between the use of emotional support animals and mental well-being of students with mental health disorders. This study is designed to illustrate the increase in sense of well-being in patients with mental health disorders who utilize ESA’s. This study applies both a qualitative and quantitative study design, the qualitative design of this study is phenomenological. …

Desolation, Kiara Adelina Hernandez Padron

UNO Student Research and Creative Activity Fair

Desolation was made in mind with my late aunt's mental illness, schizophrenia. Though I don't know what it's like having it, listening to her in the past and others about her hardships made me think about her mindset constantly throughout her whole life. This sculpture was made by digitally mapping out the composition, cutting out individual pieces of wood with each layer representing the depth of the many heads of emptiness.

Russians Fleeing Putin’S Country: Trauma, Daily Stressors, Anxiety, Depression, Post Traumatic Stress Disorder, Maria Mccready, David Witherington, Steven Verney, Dmitry Boltyanskiy

Brain & Behavioral Health Research Day

The turmoil unleashed by the Russian invasion of Ukraine in February 2022 triggered a mass migration of individuals from Russia to nearby countries like Armenia and Georgia. Amidst this upheaval, concerns have arisen regarding the mental well-being of Russian emigrants and their experiences during this turbulent period. To bridge this gap in knowledge, our study aims to examine the mental health status of adult Russian emigrants who departed from their homeland after the beginning of the conflict.

Drawing from a sample of 67 participants, comprising 30 females and 3 non-binary individuals, our research focuses on communities in Armenia and Georgia, …