Reproductive and Urinary Physiology Commons^™

Effects Of Increased Levels Of Relaxin Hormone In Women During Pregnancy In Relation To Spondylolisthesis: A Literature Review, Joselin R. Guerrero Rapalo

Honors Theses

No abstract provided.

The Impact Of Dietary Fiber On Breast Cancer Incidence, Peyton North

Epsilon Sigma at-Large Research Conference

Abstract

Introduction & Background

The role of dietary fiber in breast cancer etiology remains unclear. A negative correlation may be due to fiber’s ability to stave off obesity and aid in the extraction of serum estrogen, two known risk factors for the disease. Effects may differ by source, and type, of fiber. Most of the data available is from research with non-Hispanic white women. However, fiber intake may vary significantly across cultures.

Purpose Statement & Question

The research sought to investigate whether an increased intake of dietary fiber was associated with a corresponding decrease in the incidence of breast cancer. …

Urinary Incontinence: Understanding The Silent Plight Of Women, Yasmin Nadeem Parpio, Anmol Minaz, Sonia Ijaz Haider

School of Nursing & Midwifery

Urinary incontinence (UI) is defined as the complaint of involuntary loss of urine. UI affects both men and women but is more common in women. It has been identified as a World Health Organization priority. The burden related to UI at local, national, and global levels is huge and its impact in terms of physical, social, mental, and financial aspects makes it a concerning issue. However, there exist several barriers in terms of knowledge and attitude in seeking healthcare among women experiencing UI. This calls upon a multi-disciplinary approach involving professionals from different disciplines and tackling it with collaborative and …

Microplastics, The Environment, And Reproductive Health: How Is The Accumulation Of Microplastics In Our Environment And Bodies Impacting Reproductive Health?, Katherine Hayward

Independent Study Project (ISP) Collection

As global trends in both production and consumption of plastics continue to evolve, the bioaccumulation and biomagnification of microplastic particles in our everyday lives follow suit. This increasingly relevant problem has only recently been explored in the context of global health, and more specifically, reproductive health. Along with this steady increase in plastics and our exposure to them, researchers have separately observed adverse patterns in reproductive health. The chemicals involved throughout the microplastic life cycle may be playing a key role in these simultaneous patterns. With the aid of previous studies and publications on microplastics, exposure pathways, endocrine disruptors, and …

Exposure To Family Planning Messages And Teenage Pregnancy: Results From The 2017 Philippine National Demographic And Health Survey, Veincent Christian F. Pepito, Arianna Maever L. Amit, Clinton S. Tang, Luis Miguel B. Co, Neil Andrew K. Aliazas, Sarah J. De Los Reyes, Raymundo S. Baquiran, Lourdes Bernadette S. Tanchanco

Ateneo School of Medicine and Public Health Publications

Background

Teenage pregnancy is known to have physical, emotional, and psychosocial effects. Because of these risks, family planning and contraception messages have been disseminated in various forms of media, but their association with teenage pregnancy has not been studied previously in the Philippines. This study aims to examine the association between exposure to various family planning and contraception messages disseminated in various media channels and pregnancy among Filipino women aged 15–19. The study also intended to examine interactions between the different media channels where these family planning and contraception messages are being disseminated on their effect on teenage pregnancy.

Methods …

Ambiguous Genitalia: A Medical, Surgical, Psychiatric And Ethical Concern, Saachi M. Khanna, Anoush Sardesai Sadat, Ranjani Rammohan, Sundeep Payyanur Thotan

Manipal Journal of Medical Sciences

Disorders of Sexual Differentiation or DSDs are congenital anomalies which lead to the abnormal development of the internal and external genitalia. Our main objective in this review was to bring to light the psychiatric side of healthcare for a patient with ambiguous genitalia and DSD and create more awareness of the ethical aspects of the condition. The most important step in the management of DSD is the avoidance of prematurely designating sex or using gendered pronouns, as well as reassuring the family. Treatment is not singular, but a multidisciplinary approach. It involves medical management and surgical correction of the genitalia. …

Understanding One Dietary Supplement For Pcos, Eva Schofield

Capstone Showcase

Poly Cystic Ovarian Syndrome (PCOS) is the most common condition in women of reproductive age, yet nearly 70% of individuals with PCOS remain undiagnosed. For many women who do receive a diagnosis, it takes experiencing symptoms for two years or longer and receiving care from an average of 3 different providers before a diagnosis can be established. In an environment where prevalence is high, diagnosis rate is low and delayed, and dissatisfaction is prevalent regarding the health care women receive, many patients may turn to self-diagnosis and online resources to find their own therapeutic options. This CME article aims to …

Safety, Efficacy, And Reversibility Of Novel Male Contraceptives For Improved Pregnancy Prevention, Danielle Anton

Capstone Showcase

Unintended pregnancy is a global issue that can result from contraceptive failure or from a lack of contraceptive use. A literature search was conducted to explore novel methods of male contraceptives being developed for improved pregnancy prevention. Seven articles were selected, reporting on either oral contraceptive pills, transdermal gel, injectable hormonal, or bilateral intravas deferens polymer injection. The most common adverse events reported across all studies include changes in libido, mood, weight gain, acne, and headache. After reaching hormone and sperm concentration levels sufficient for pregnancy prevention, authors reported complete reversibility of contraceptive effects. Four studies described changes in various …

Does Administration Of Probiotics To Women Aiming To Get Pregnant Reduce The Risk Of Pregnancy Complications?, Olivia Kreider

Capstone Showcase

This paper aims to assess the role of the vaginal and uterine microbiota in pregnancy complications, specifically miscarriages. With 1% of women experiencing recurrent miscarriages, the need to further research risk factors for miscarriages is evident. The findings of this research revealed there may be a place for probiotics in the prevention of pregnancy complications. Studies have shown that there is an impact of various bacteria within the uterine and vaginal microbiota on conceiving and maintaining healthy, full-term pregnancies. Considering these findings, it is recommended that healthcare providers consider recommending probiotic supplements to anyone aiming to conceive, especially those who …

“It’S About Our Bodies… We Have The Right To Know This Stuff”: A Qualitative Focus Group Study On Australian Women’S Perspectives On Breast Density, Brooke Nickel, Hankiz Dolan, Stacy Carter, Nehmat Houssami, Meagan E. Brennan, Jolyn Hersch, Angela Verde, Lisa Vaccaro, Kirsten Mccaffery

Medical Papers and Journal Articles

Objective

This study aimed to explore Australian women’s current knowledge, perspectives and attitudes about breast density (BD); and information needs to inform effective evidence-based communication strategies.

Methods

Fourteen online focus group sessions with a total of 78 women in New South Wales and Queensland, Australia aged 40–74 years without a personal diagnosis of breast cancer were conducted. Audio-recorded data was transcribed and analysed thematically.

Results

Women had a very limited knowledge of BD. Overall, women expressed a preference for more frequent mammograms and/or supplemental screening should they be told they had dense breasts, despite being presented with information on potential …

Fertility Control Options For Management Of Free-Roaming Horse Populations, Ursula S. Bechert, John W. Turner Jr., Dan L. Baker, Douglas C. Eckery, Jason E. Bruemmer, Candace C. Lyman, Tulio M. Prado, Sarah R. B. King, Mark A. Fraker

Human–Wildlife Interactions

The management of free-roaming horses (Equus ferus) and burros (E. asinus) in the United States has been referred to as a “wicked problem” because, although there are population control options, societal values will ultimately determine what is acceptable and what is not. In the United States, free-roaming equids are managed by different types of organizations and agencies, and the landscapes that these animals inhabit vary widely in terms of access, size, topography, climate, natural resources, flora, and fauna. This landscape diversity, coupled with contemporary socioeconomic and political environments, means that adaptive management practices are needed to …

Gambaran Epidemiologi Hepatitis A Berdasarkan Data Kejadian Luar Biasa Dan Data Kasus Di Kabupaten Bogor Tahun 2019, Nurjannah Nurjannah, Asri Adisasmita Prof

Jurnal Epidemiologi Kesehatan Indonesia

Kejadian luar biasa (KLB) Hepatitis A Kabupaten Bogor terus meningkat setiap tahunnya. Pada tahun 2018 terdapat 29 kasusdan pada tahun 2019 meningkat hingga 495 kasus. Penelitian ini bertujuan untuk menggambarkan epidemiologi berdasarkan orang, tempat, waktu. Hasil penelitian ini diharapkan dapat digunakan sebagai dasar upaya intevensi yang lebih optimaldan tepat sasaran. Data penelitian diambil dari laporan KLB dandari data kasus Hepatitis A di Dinas Kesehatan Kabupaten Bogor dari Januari-Desember 2019 dan didokumentasikan ke dalam tabel observasi, pengambilan data dilakukan pada Bulan Februari2020 dengan desain penelitian case series. Hasil penelitian ini menunjukkan dari 495 kasus yang mengalami gejala klinis,11,3% terkonfimasi positif, sebagian …

Hubungan Antara Riwayat Kunjungan Antenatal Care (Anc) Dengan Kejadian Lahir Mati Di Indonesia, Lila Kesuma Hairani, Asri Adisasmita Prof

Jurnal Epidemiologi Kesehatan Indonesia

Pada tahun 2015, sebanyak 65% dari total kelahiran mati diseluruh dunia disumbang oleh sepuluh negara dengan jumlah kelahiran mati terbanyak. Indonesia menempati posisi ke-8 dengan total sebanyak 73.400 kejadian dengan angka lahir mati (stillbirth rate/SBR) sebesar 13 per 1.000 kelahiran. Rendahnya cakupan layanan antenatal diduga berhubungan secara kuatdengan rendahnya lahir mati antepartum. Studi ini dilakukan dengan tujuan untuk melihat hubungan riwayat kunjungan antenatal (antenatal care/ANC) dengan kejadian lahir mati diIndonesia menggunakan data sekunder yang bersumber dari IFLS 5 tahun 2014. Desain penelitian ini berupa studi potonglintang dengan total sampel yang digunakan adalah sebesar 6.314 kelahiran. Analisis data dilakukan hingga tingkat …

Hubungan Faktor Pejamu Dan Lingkungan Dengan Pneumonia Balita Di 5 Provinsi Di Pulau Sulawesi, Alfi Lailiyah, Nuning Maria Kiptiyah

Jurnal Epidemiologi Kesehatan Indonesia

Pneumonia merupakan penyakit menular yang menginfeksi paru-paru. Period prevalence pneumonia balita di 5 provinsi di Sulawesi lebih tinggi dibanding angka nasional. Penelitian ini bertujuan untuk mendapatkan gambaran dan faktor-faktor yang berhubungan dengan pneumonia balita di 5 Provinsi di Pulau Sulawesi. Data penelitian ini bersumber dari Survei Demografi dan Kesehatan Indonesia (SDKI) 2012. Desain dalam penelitian ini adalah cross-sectional dengan uji chi-square dan hasil ukur prevalence ratio (PR). Variabel pada penelitian ini adalah faktor pejamu (umur balita, jenis kelamin, berat badan lahir, pemberian vitamin A, status imunisasi campak dan DPT) dan faktor lingkungan (pendidikan ibu, tempat tinggal, bahan bakar memasak, keberadaan …

Hubungan Hipertensi Dengan Mortalitas Pasien Covid-19 Di Tangerang Selatan, Choirunnisa Choirunnisa, Helda Helda

Jurnal Epidemiologi Kesehatan Indonesia

Covid-19 (Coronavirus Disease-2019) adalah penyakit yang disebabkan oleh virus SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2). Usia tua (>65 tahun), jenis kelamin laki-laki, hipertensi, penyakit kardiovaskular, diabetes, PPOK dan kanker dapat meningkatkan risiko kematian akibat Covid-19. Kota Tangerang Selatan berpotensi mengalami kenaikan kasus Covid-19 karena berbatasan langsung dengan DKI Jakarta yang merupakan episentrum persebaran Covid-19, sehingga peneliti tertarik untuk melakukan penelitian ini. Desain penelitian ini adalah studi analitik kasus kontrol menggunakan data sekunder dari penelusuran epidemiologi (PE) Dinas Kesehatan Kota Tangerang Selatan bulan Maret 2020-Juli 2021. Data PE diperoleh dari portal New All Record (NAR) yang memuat data pasien Covid-19 termasuk …

Hubungan Status Gizi Dengan Prestasi Belajar Siswa Kelas 1-3 Sekolah Dasar, Muhammad Hidayat Sahid, Asri Adisasmita Prof, Ratna Djuwita

Jurnal Epidemiologi Kesehatan Indonesia

Status gizi merupakan ukuran keberhasilan dalam pemenuhan nutrisi anak yang diukur berdasarkan berat badan dan tinggi badan anak. Data status gizi pada anak usia umur 5-12 tahun di DKI Jakarta menunjukkan underweight 14,0%, stunting 22,7%, wasting 9,9%, dan overweight 6,8%. Data secara spesifik untuk wilayah Jakarta Selatan adalah underweight 7,4%, stunting 17,8%, wasting 6,3%, dan overweight 7,3%. Dari data tersebut didapatkan gambaran mengenai permasalahan gizi yang terjadi di DKI Jakarta. Permasalahan gizi memiliki dampak pada tumbuh kembang anak. Gizi merupakan salah satu faktor penting yang berpengaruh terhadap prestasi akademik siswa. Tujuan dari penelitian ini adalah untuk mengetahui hubungan status gizi …

Breakthroughs In Hormonal Male Contraception, Alexander Patton, Seth Vann

Physician Assistant Capstones, 2020-current

Objective: Assess the efficacy of a nestorone plus testosterone gel at suppressing progestin levels and spermatogenesis.

Design: Systematic literature review.

Methods: Searches were done in PubMed and Dartmouth library using the terms nestorone, randomized control trial, human, and male. Limits used while searching included published in the last 10 years, randomized control trials, and English.

Results: Using the search criteria the following three studies were found that met the inclusion/exclusion criteria of this study: Ilani et al, Zitzmann et al, and Anawalt et al. All three studies were found on PubMed and reference the Ilani et al study.

Conclusion: Nestorone …

Periaortic Venous Necklace And Renal Right Double Arteries; Case Report, Petru Bordei, Constantin Andrei Rusali, Constantin Ionescu, Dragos Serban, Valeriu Ardeleanu

Journal of Mind and Medical Sciences

The case was found on an organic sample consisting of the two kidneys with the renal pedicles and the corresponding segments of the abdominal aorta and inferior vena cava. From the inferior face of the left renal vein, on the lower side of the aorta, a venous branch with an upward path of 8.02 mm was detached, passing on the anterior face of the aorta, passing before its right side, in order to end on the left side of the inferior vena cava, 13.9 mm above the end of the left renal vein in the inferior vena cava, this branch …

The Onset Of Exercise-Associated Hyponatremia And Individual Differences In Inappropriate Arginine Vasopressin Excretion: A Review Of Proposed Mechanisms, Michelle Stehman, Stephen A. Maris

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 10, 2021. Exercise-associated hyponatremia (EAH) has been reported to develop during endurance events such as triathlons and marathons. As these events become more popular, the incidence of developing EAH also increases. The development of EAH is commonly associated with the overconsumption of hypotonic fluids such as water and tends to be more prevalent in females. There is also evidence to suggest the inappropriate secretion of arginine vasopressin (AVP) leading to water retention may predispose an individual for developing EAH, especially when coupled with the overconsumption of fluids. Recent research …

Hubungan Obesitas Dengan Kejadian Hipertensi Pada Lansia Di Posyandu Lansia Di Wilayah Kerja Puskesmas Pb Selayang Ii Kecamatan Medan Selayang, Medan, Hazella Rissa Valda Asari, Helda Helda

Jurnal Epidemiologi Kesehatan Indonesia

Populasi individu di seluruh dunia berusia 65 tahun dan lebih tua terus meningkat. Prevalensi hipertensi di Indonesia adalah 26,5%.Situasi hipertensi terus meningkat seiring dengan epidemiologinya yang meluas, yang berkontribusi terhadap meningkatnya beban global penyakit secara keseluruhan. Salah satu faktor hipertensi ialah obesitas. Studi Framingham menunjukkan bahwa baik pria maupun wanita mengalami peningkatan tekanan darah dengan peningkatan kelebihan berat badan. Mengetahui hubungan obesitas dengan hipertensi pada lansia. Desain potong lintang digunakan untuk penelitian yang dilaksanakan pada 9 posyandu lansia di wilayah kerja Puskesmas PB Selayang II pada bulan Agustus 2017. Populasi penelitian adalah lansia yang mengunjungi ke sembilan posyandu lansia di …

Determinan Konsistensi Penggunaan Kondom Pada Laki-Laki Seks Dengan Laki-Laki (Lsl) Non-Pekerja Seks: Studi Potong Lintang, Arum Zulaikhah, Sudarto Ronoatmodjo

Jurnal Epidemiologi Kesehatan Indonesia

Kasus baru HIV di Indonesia cenderung terus mengalami peningkatan. Sedangkan, tren kasus baru di dunia sudah mengalami penurunan. Laki-laki Seks dengan laki-laki (LSL) merupakan kelompok risiko tinggi HIV. Upaya pencegahan penularan HIV erat kaitannya dengan perilaku seks. Studi ini menggunakan 1.161 sampel Survei Terpadu Biologi dan Perilaku (STBP) 2015 pada kelompok LSL yang termasuk bukan pekerja seks. Studi cross sectional ini bertujuan untuk menganalisis determinan perilaku seks konsistensi penggunaan kondom dengan analisis hingga bivariat dengan menggunakan chi-square dan prevalence ratio. Data didapatkan dengan metode respondent driven sampling (RDS) yang kemudian mengeksklusi LSL pekerja seks. Hasil menunjukkan bahwa faktor-faktor yang berhubungan …

Hubungan Tingkat Pengetahuan Tentang Alat Kb Dengan Pemakaian Kontrasepsi Modern Pada Wanita Remaja Kawin Di Pulau Jawa (Analisis Sdki 2017), Priskatindea Priskatindea, Sudarto Ronoatmodjo

Jurnal Epidemiologi Kesehatan Indonesia

Prevalensi pemakaian metode KB modern pada wanita kawin usia remaja di Pulau Jawa tahun 2017 tergolong masih rendah, yakni 27,8%. Terbatasnya tingkat pengetahuan remaja mengenai pilihan kontrasepsi adalah salah satu hambatan pemakaian kontrasepsi pada remaja. Penelitian ini memiliki tujuan untuk mengetahui hubungan antara tingkat pengetahuan tentang alat/cara KB dengan pemakaian kontrasepsi modern pada wanita kawin usia remaja di Pulau Jawa. Penelitian ini menggunakan data sekunder dengan menganalisis hasil dari Survei Demografi dan Kesehatan Indonesia (SDKI) Tahun 2017. Sampel adalah 309 orang wanita berusia 15-19 tahun yang berdomisili di Pulau Jawa dengan status kawin. Pada hasil ditemukan sebanyak 62,4% responden memakai …

Berat Badan Lahir Rendah (Bblr) Sebagai Determinan Terjadinya Ispa Pada Balita Analisis Data Sdki Tahun 2017, Desinta Ayu Lestari, Asri Adisasmita Prof

Jurnal Epidemiologi Kesehatan Indonesia

No abstract provided.

Studi Endemisitas Dan Epidemiologi Deskriptif Malaria Di Kabupaten Purbalingga Tahun 2010-2019, Ghea Efranandhita Sukendar, Dwi Sarwani Sri Rejeki

Jurnal Epidemiologi Kesehatan Indonesia

Salah satu permasalahan kesehatan di Jawa Tengah adalah kejadian malaria. Kondisi lingkungan dan perilaku mempunyai peran dalam penyebaran malaria. Gambaran endemisitas dan upaya pengendalian yang diperlukan sebagai dasar perencanaan tindakan pengendalian malaria. Belum ada data yang menyajikan endemisitas malaria dari tahun 2010-2019 di Kabupaten Purbalingga. Penelitian ini bertujuan untuk mendeskripsikan endemisitas dan menggambarkan kejadian malaria berdasarkan variabel orang, tempat dan waktu dan upaya pengendalian yang sudah dilakukan periode tahun 2010-2019 di Kabupaten Purbalingga. Jenis penelitian yaitu deskriptif kuantitatif dengan populasi yaitu seluruh kasus malaria yang tercatat di dinas Kesehatan Kabupaten Purbalingga periode Januari 2010 sampai Desember 2019. Sampel merupakan total …

The Analysis Of Risk Factors Associated With Women's Urinary Incontinence; Literature Review, Denisa Oana Balalau, Octavian Gabriel Olaru, Nicolae Bacalbasa, Stana Paunica, Daniela Gabriela Balan, Anca Daniela Stanescu

Journal of Mind and Medical Sciences

Urinary incontinence (UI) is a common condition among women. Approximately 50% of them had an involuntary loss of urine at least once in their lifetime. It can be present during sexual activity, contributing to sexual dysfunction and often associated with anxiety or even depression, thus having a negative impact on the quality of life. The incidence of UI is related to the existence of predisposing factors. The best known are: age, weight, family history, race/ ethnicity, number of pregnancies and mode of birth, history of genitourinary interventions and factors related to ordinary habits: smoking, caffeine consumption, oral contraceptives. Studies on …

Methamphetamine Associated Cardiomyopathy In Pregnancy: The Distinctions And The Implications, Ashan Hatharasinghe, Hossein Akhondi

HCA Healthcare Journal of Medicine

Introduction

Methamphetamine associated cardiomyopathy (MAC) and peripartum cardiomyopathy (PPCM) are both rare obstetric conditions. Literature regarding methamphetamine associated cardiomyopathy in the obstetric population is limited, and it can be difficult to make the distinction between the two given the similarities in clinical presentation. However similar, there are significant distinctions in the pathophysiology of these two that can help clinicians with the management process.

Clinical Findings and Outcomes

This case involves a 35-year-old Hispanic G6P5005 at 37 weeks gestation presenting with acute respiratory failure secondary to acute decompensated heart failure with reduced ejection fraction and superimposed preeclampsia leading to urgent cesarean …

Chronic Use Of Non-Medical Abdominal Compressors: Medical And Psychological Implications, Sawsan Edriss, Bushra Azom, Manar Edriss, Mustafa Edriss, Ann-Cathrin Guertler, Eva Waineo Md, Diane L. Levine Md

Medical Student Research Symposium

The popularity of waist cinchers, shapewear, abdominal binders, corsets, and waist trainers has increased in the population. Although corsets have been part of western fashion since the 18th century, abdominal compressors remain in style even today. In 2018, sales for shapewear worldwide were estimated at 2.26 billion USD. 1 Despite its popularity, shapewear safety and medical effects have not been widely studied.

In 1968, “Pantygirdle Syndrome” was described, attributing vulvitis, urethritis, and urinary tract infections to materials used from the “pantygirdle”. 2 The article describes that the girdle caused gastrointestinal symptoms with diaphragmatic and stomach displacement causing gastro-esophageal reflux disease …

Targeting Epigenetic Mechanisms In Endometriosis, Sarah Elizabeth Brunty

Theses, Dissertations and Capstones

Endometriosis is a complex and elusive gynecological disease in which the inner lining of the uterus grows in locations outside of the uterus and forms lesions. It is known to affect 1 in 9 women of reproductive age worldwide. Symptoms of endometriosis include severe pain, heavy periods, and infertility. While multiple theories of origin exist, none fully encompass all aspects of the disease, although all theories agree that this is an inflammation-driven disease. Due to this, many researchers are turning towards epigenetics to explain the initiation and progression of endometriosis. However, what is causing these epigenetic changes is still a …

Efficacy And Safety Of Once-Daily Vibegron For Treatment Of Overactive Bladder In Patients Aged ≥65 And ≥75 Years: Subpopulation Analysis From The Empowur Randomized, International, Phase Iii Study, Susann Varano, David Staskin, Jeffrey Frankel, Denise Shortino, Rachel Jankowich, Paul N. Mudd

Physician Assistant Studies Faculty Publications

Background

Overactive bladder (OAB) is common among older adults. The efficacy and safety of vibegron for the treatment of OAB were demonstrated in the international, phase III EMPOWUR trial. This subpopulation analysis from EMPOWUR assessed the efficacy and safety of vibegron in patients aged ≥ 65 and ≥ 75 years.

Methods

In EMPOWUR, patients with OAB were randomly assigned 5:5:4 to receive once-daily vibegron 75 mg, placebo, or tolterodine 4 mg extended release, respectively, once daily for 12 weeks. Coprimary efficacy endpoints were change from baseline at week 12 in average daily number of micturitions and urge urinary incontinence (UUI) …

Routinely Collected Antenatal Data For Longitudinal Prediction Of Preeclampsia In Nulliparous Women: A Population‑Based Study, Anna Sandstrom, Jonathan Snowden, Matteo Bottai, Olof Stephansson, Anna-Karin Wikström

OHSU-PSU School of Public Health Faculty Publications and Presentations

The objective was to evaluate the sequentially updated predictive capacity for preeclampsia during pregnancy, using multivariable longitudinal models including data from antenatal care. This population-based cohort study in the Stockholm-Gotland Counties, Sweden, included 58,899 pregnancies of nulliparous women 2008–2013. Prospectively collected data from each antenatal care visit was used, including maternal characteristics, reproductive and medical history, and repeated measurements of blood pressure, weight, symphysis-fundal height, proteinuria, hemoglobin and blood glucose levels. We used a shared-effects joint longitudinal model including all available information up until a given gestational length (week 24, 28, 32, 34 and 36), to update preeclampsia prediction sequentially. …